Transient hypoxia stimulates mitochondrial biogenesis in brain subcortex by a neuronal nitric oxide synthase-dependent mechanism

Journal of Neuroscience

Volumn 28, Issue 9, 2008, Pages 2015-2024

  Gutsaeva, Diana R ^a,b   Carraway, Martha Sue ^a   Suliman, Hagir B ^a   Demchenko, Ivan T ^a,b   Shitara, Hiroshi ^c   Yonekawa, Hiromichi ^c   Piantadosi, Claude A ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b SECHENOV INSTITUTE OF EVOLUTIONARY PHYSIOLOGY AND BIOCHEMISTRY   (Russian Federation)

^c TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

Author keywords

Brain metabolism; Energy metabolism; Hypoxia; Mitochondria; Mitochondrial biogenesis; Nitric oxide

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GENOMIC DNA; MITOCHONDRIAL DNA; NITRIC OXIDE SYNTHASE; NUCLEAR PROTEIN; NUCLEAR RESPIRATORY FACTOR 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; TRANSCRIPTION FACTOR NRF1; TRANSCRIPTION FACTOR NRF2;

ANIMAL EXPERIMENT; ARTICLE; BIOGENESIS; BRAIN CIRCULATION; BRAIN HYPOXIA; BRAIN METABOLISM; CONTROLLED STUDY; DNA EXTRACTION; ENERGY METABOLISM; IMMUNOHISTOCHEMISTRY; MITOCHONDRION; MOUSE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; TRANSCRIPTION REGULATION; WESTERN BLOTTING;

ANALYSIS OF VARIANCE; ANIMALS; ANOXIA; BRAIN; CREB-BINDING PROTEIN; DNA, MITOCHONDRIAL; ENZYME INHIBITORS; GENE EXPRESSION REGULATION; GREEN FLUORESCENT PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOCHONDRIA; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE TYPE I; NITRIC OXIDE SYNTHASE TYPE II; NUCLEAR PROTEINS; TIME FACTORS; TRANS-ACTIVATORS;

EID: 39849094082     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5654-07.2008     Document Type: Article

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