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Volumn 38, Issue 4, 2009, Pages

Analysis of differential DNA damage in the mitochondrial genome employing a semi-long run real-time PCR approach

Author keywords

[No Author keywords available]

Indexed keywords

HYDROGEN PEROXIDE; MITOCHONDRIAL DNA; MONOPHENOL MONOOXYGENASE; REACTIVE OXYGEN METABOLITE;

EID: 77951186338     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkp1082     Document Type: Article
Times cited : (127)

References (48)
  • 2
    • 0142028110 scopus 로고    scopus 로고
    • Mitochondrial oxidative stress and mitochondrial DNA
    • Kang, D. and Hamasaki, N. (2003) Mitochondrial oxidative stress and mitochondrial DNA. Clin. Chem. Lab. Med., 41, 1281-1288.
    • (2003) Clin. Chem. Lab. Med. , vol.41 , pp. 1281-1288
    • Kang, D.1    Hamasaki, N.2
  • 4
    • 0031032817 scopus 로고    scopus 로고
    • Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress
    • USA
    • Yakes, F.M. and Van Houten, B. (1997) Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress. Proc. Natl Acad. Sci. USA, 94, 514-519.
    • (1997) Proc. Natl Acad. Sci. , vol.94 , pp. 514-519
    • Yakes, F.M.1    Van Houten, B.2
  • 5
    • 44949213717 scopus 로고    scopus 로고
    • Mitochondrial DNA damage and repair in neurodegenerative disorders
    • Yang, J.L., Weissman, L., Bohr, V.A. and Mattson, M.P. (2008) Mitochondrial DNA damage and repair in neurodegenerative disorders. DNA Repair, 7, 1110-1120.
    • (2008) DNA Repair , vol.7 , pp. 1110-1120
    • Yang, J.L.1    Weissman, L.2    Bohr, V.A.3    Mattson, M.P.4
  • 7
    • 0024541837 scopus 로고
    • Mitochondrial DNA mutations as an important contributor to ageing and degenerative diseases
    • Linnane, A.W., Marzuki, S., Ozawa, T. and Tanaka, M. (1989) Mitochondrial DNA mutations as an important contributor to ageing and degenerative diseases. Lancet, 1, 642-645.
    • (1989) Lancet , vol.1 , pp. 642-645
    • Linnane, A.W.1    Marzuki, S.2    Ozawa, T.3    Tanaka, M.4
  • 9
    • 3042517030 scopus 로고    scopus 로고
    • Mitochondrial mutagenesis and oxidative stress in human prostate cancer
    • Chen, J.Z. and Kadlubar, F.F. (2004) Mitochondrial mutagenesis and oxidative stress in human prostate cancer. J. Environ. Sci. Health, 22, 1-12.
    • (2004) J. Environ. Sci. Health , vol.22 , pp. 1-12
    • Chen, J.Z.1    Kadlubar, F.F.2
  • 10
    • 45449088101 scopus 로고    scopus 로고
    • Mitochondrial DNA repair in aging and disease
    • Druzhyna, N.M., Wilson, G.L. and Ledoux, S.P. (2008) Mitochondrial DNA repair in aging and disease. Mech. Ageing Dev., 129, 383-390.
    • (2008) Mech. Ageing Dev. , vol.129 , pp. 383-390
    • Druzhyna, N.M.1    Wilson, G.L.2    Ledoux, S.P.3
  • 11
    • 48949119268 scopus 로고    scopus 로고
    • Age related mitochondrial degenerative disorders in humans
    • Reeve, A.K., Krishnan, K.J. and Turnbull, D.M. (2008) Age related mitochondrial degenerative disorders in humans. Biotechnol. J., 3, 750-756.
    • (2008) Biotechnol. J. , vol.3 , pp. 750-756
    • Reeve, A.K.1    Krishnan, K.J.2    Turnbull, D.M.3
  • 12
    • 0028152717 scopus 로고
    • Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease
    • Mecocci, P., MacGarvey, U. and Beal, M.F. (1994) Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease. Ann. Neurol., 36, 747-751.
    • (1994) Ann. Neurol. , vol.36 , pp. 747-751
    • Mecocci, P.1    MacGarvey, U.2    Beal, M.F.3
  • 13
    • 18844462415 scopus 로고    scopus 로고
    • Increased oxidative damage in nuclear and mitochondrial DNA in Alzheimer's disease
    • Wang, J., Xiong, S., Xie, C., Markesbery, W.R. and Lovell, M.A. (2005) Increased oxidative damage in nuclear and mitochondrial DNA in Alzheimer's disease. J. Neurochem., 93, 953-962.
    • (2005) J. Neurochem. , vol.93 , pp. 953-962
    • Wang, J.1    Xiong, S.2    Xie, C.3    Markesbery, W.R.4    Lovell, M.A.5
  • 14
    • 38049010515 scopus 로고    scopus 로고
    • Oxidative DNA damage in mild cognitive impairment and late-stage Alzheimer's disease
    • Lovell, M.A. and Markesbery, W.R. (2007) Oxidative DNA damage in mild cognitive impairment and late-stage Alzheimer's disease. Nucleic Acids Res., 35, 7497-7504.
    • (2007) Nucleic Acids Res. , vol.35 , pp. 7497-7504
    • Lovell, M.A.1    Markesbery, W.R.2
  • 15
    • 33750347347 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
    • Lin, M.T. and Beal, M.F. (2006) Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. Nature, 443, 787-795.
    • (2006) Nature , vol.443 , pp. 787-795
    • Lin, M.T.1    Beal, M.F.2
  • 16
    • 37049004489 scopus 로고    scopus 로고
    • Mitochondria in the aetiology and pathogenesis of Parkinson's disease
    • Schapira, A.H. (2008) Mitochondria in the aetiology and pathogenesis of Parkinson's disease. Lancet Neurol., 7, 97-109.
    • (2008) Lancet Neurol , vol.7 , pp. 97-109
    • Schapira, A.H.1
  • 17
    • 0035668684 scopus 로고    scopus 로고
    • Increased oxidative damage to DNA in a transgenic mouse model of Huntington's disease
    • Bogdanov, M.B., Andreassen, O.A., Dedeoglu, A., Ferrante, R.J. and Beal, M.F. (2001) Increased oxidative damage to DNA in a transgenic mouse model of Huntington's disease. J. Neurochem., 79, 1246-1249.
    • (2001) J. Neurochem. , vol.79 , pp. 1246-1249
    • Bogdanov, M.B.1    Andreassen, O.A.2    Dedeoglu, A.3    Ferrante, R.J.4    Beal, M.F.5
  • 18
    • 0033520166 scopus 로고    scopus 로고
    • Oxidative damage to mitochondrial DNA in Huntington's disease parietal cortex
    • Polidori, M.C., Mecocci, P., Browne, S.E., Senin, U. and Beal, M.F. (1999) Oxidative damage to mitochondrial DNA in Huntington's disease parietal cortex. Neurosci. Lett., 272, 53-56.
    • (1999) Neurosci. Lett. , vol.272 , pp. 53-56
    • Polidori, M.C.1    Mecocci, P.2    Browne, S.E.3    Senin, U.4    Beal, M.F.5
  • 20
    • 0035906260 scopus 로고    scopus 로고
    • Oxidative damage to mitochondrial DNA in spinal motoneurons of transgenic ALS mice
    • Warita, H., Hayashi, T., Murakami, T., Manabe, Y. and Abe, K. (2001) Oxidative damage to mitochondrial DNA in spinal motoneurons of transgenic ALS mice. Brain Res., 89, 147-152.
    • (2001) Brain Res. , vol.89 , pp. 147-152
    • Warita, H.1    Hayashi, T.2    Murakami, T.3    Manabe, Y.4    Abe, K.5
  • 21
    • 30344432706 scopus 로고    scopus 로고
    • Role of mitochondrial DNA in toxic responses to oxidative stress
    • Van Houten, B., Woshner, V. and Santos, J.H. (2006) Role of mitochondrial DNA in toxic responses to oxidative stress. DNA Repair, 5, 145-152.
    • (2006) DNA Repair , vol.5 , pp. 145-152
    • Van Houten, B.1    Woshner, V.2    Santos, J.H.3
  • 22
    • 33744721699 scopus 로고    scopus 로고
    • Quantitative PCR-based measurement of nuclear and mitochondrial DNA damage and repair in mammalian cells
    • Santos, J.H., Meyer, J.N., Mandavilli, B.S. and Van Houten, B. (2006) Quantitative PCR-based measurement of nuclear and mitochondrial DNA damage and repair in mammalian cells. Methods Mol. Biol., 314, 183-199.
    • (2006) Methods Mol. Biol. , vol.314 , pp. 183-199
    • Santos, J.H.1    Meyer, J.N.2    Mandavilli, B.S.3    Van Houten, B.4
  • 23
    • 60249085506 scopus 로고    scopus 로고
    • Quantification of mitochondrial DNA (mtDNA) damage and error rates by real-time QPCR
    • Edwards, J.G. (2009) Quantification of mitochondrial DNA (mtDNA) damage and error rates by real-time QPCR. Mitochondrion, 9, 31-35.
    • (2009) Mitochondrion , vol.9 , pp. 31-35
    • Edwards, J.G.1
  • 26
    • 43549122572 scopus 로고    scopus 로고
    • Parkin protects against tyrosinase-mediated dopamine neurotoxicity by suppressing stress-activated protein kinase pathways
    • Hasegawa, T., Treis, A., Patenge, N., Fiesel, F.C., Springer, W. and Kahle, P.J. (2008) Parkin protects against tyrosinase-mediated dopamine neurotoxicity by suppressing stress-activated protein kinase pathways. J. Neurochem., 105, 1700-1715.
    • (2008) J. Neurochem. , vol.105 , pp. 1700-1715
    • Hasegawa, T.1    Treis, A.2    Patenge, N.3    Fiesel, F.C.4    Springer, W.5    Kahle, P.J.6
  • 27
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • Livak, K.J. and Schmittgen, T.D. (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods, 25, 402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 28
    • 0034431467 scopus 로고    scopus 로고
    • Analysis of gene-specific DNA damage and repair using quantitative polymerase chain reaction
    • Ayala-Torres, S., Chen, Y., Svoboda, T., Rosenblatt, J. and Van Houten, B. (2000) Analysis of gene-specific DNA damage and repair using quantitative polymerase chain reaction. Methods, 22, 135-147.
    • (2000) Methods , vol.22 , pp. 135-147
    • Ayala-Torres, S.1    Chen, Y.2    Svoboda, T.3    Rosenblatt, J.4    Van Houten, B.5
  • 29
    • 34548495323 scopus 로고    scopus 로고
    • The mitochondrial transcription factor TFAM coordinates the assembly of multiple DNA molecules into nucleoid-like structures
    • Kaufman, B.A., Durisic, N., Mativetsky, J.M., Costantino, S., Hancock, M.A., Grutter, P. and Shoubridge, E.A. (2007) The mitochondrial transcription factor TFAM coordinates the assembly of multiple DNA molecules into nucleoid-like structures. Mol. Biol. Cell, 18, 3225-3236.
    • (2007) Mol. Biol. Cell , vol.18 , pp. 3225-3236
    • Kaufman, B.A.1    Durisic, N.2    Mativetsky, J.M.3    Costantino, S.4    Hancock, M.A.5    Grutter, P.6    Shoubridge, E.A.7
  • 30
    • 0035984909 scopus 로고    scopus 로고
    • Regulation of mitochondrial D-loops by transcription factor A and single-stranded DNA-binding protein
    • Takamatsu, C., Umeda, S., Ohsato, T., Ohno, T., Abe, Y., Fukuoh, A., Shinagawa, H., Hamasaki, N. and Kang, D. (2002) Regulation of mitochondrial D-loops by transcription factor A and single-stranded DNA-binding protein. EMBO Rep., 3, 451-456.
    • (2002) EMBO Rep. , vol.3 , pp. 451-456
    • Takamatsu, C.1    Umeda, S.2    Ohsato, T.3    Ohno, T.4    Abe, Y.5    Fukuoh, A.6    Shinagawa, H.7    Hamasaki, N.8    Kang, D.9
  • 32
    • 0016700864 scopus 로고
    • Detection of specific sequences among DNA fragments separated by gel electrophoresis
    • Southern, E.M. (1975) Detection of specific sequences among DNA fragments separated by gel electrophoresis. J. Mol. Biol., 98, 503-517.
    • (1975) J. Mol. Biol. , vol.98 , pp. 503-517
    • Southern, E.M.1
  • 33
    • 0242574363 scopus 로고    scopus 로고
    • Induced genomic instability in irradiated germ cells and in the offspring; reconciling discrepancies among the human and animal studies
    • Niwa, O. (2003) Induced genomic instability in irradiated germ cells and in the offspring; reconciling discrepancies among the human and animal studies. Oncogene, 22, 7078-7086.
    • (2003) Oncogene , vol.22 , pp. 7078-7086
    • Niwa, O.1
  • 35
    • 0023919963 scopus 로고
    • A simple technique for quantitation of low levels of DNA damage in individual cells
    • Singh, N.P., McCoy, M.T., Tice, R.R. and Schneider, E.L. (1988) A simple technique for quantitation of low levels of DNA damage in individual cells. Exp. cell Res., 175, 184-191.
    • (1988) Exp. cell Res. , vol.175 , pp. 184-191
    • Singh, N.P.1    McCoy, M.T.2    Tice, R.R.3    Schneider, E.L.4
  • 36
    • 0025606745 scopus 로고
    • Cigarette smoking induces formation of 8-hydroxydeoxyguanosine, one of the oxidative DNA damages in human peripheral leukocytes
    • Kiyosawa, H., Suko, M., Okudaira, H., Murata, K., Miyamoto, T., Chung, M.H., Kasai, H. and Nishimura, S. (1990) Cigarette smoking induces formation of 8-hydroxydeoxyguanosine, one of the oxidative DNA damages in human peripheral leukocytes. Free Radical Res. Commun., 11, 23-27.
    • (1990) Free Radical Res. Commun. , vol.11 , pp. 23-27
    • Kiyosawa, H.1    Suko, M.2    Okudaira, H.3    Murata, K.4    Miyamoto, T.5    Chung, M.H.6    Kasai, H.7    Nishimura, S.8
  • 37
    • 50349091399 scopus 로고    scopus 로고
    • Quantification of DNA damage products resulting from deamination, oxidation and reaction with products of lipid peroxidation by liquid chromatography isotope dilution tandem mass spectrometry
    • Taghizadeh, K., McFaline, J.L., Pang, B., Sullivan, M., Dong, M., Plummer, E. and Dedon, P.C. (2008) Quantification of DNA damage products resulting from deamination, oxidation and reaction with products of lipid peroxidation by liquid chromatography isotope dilution tandem mass spectrometry. Nat. Protocols, 3, 1287-1298.
    • (2008) Nat. Protocols , vol.3 , pp. 1287-1298
    • Taghizadeh, K.1    McFaline, J.L.2    Pang, B.3    Sullivan, M.4    Dong, M.5    Plummer, E.6    Dedon, P.C.7
  • 38
    • 0034732995 scopus 로고    scopus 로고
    • Hydroperoxide-induced DNA damage and mutations
    • Termini, J. (2000) Hydroperoxide-induced DNA damage and mutations. Mut. Res., 450, 107-124.
    • (2000) Mut. Res. , vol.450 , pp. 107-124
    • Termini, J.1
  • 39
    • 0037452679 scopus 로고    scopus 로고
    • Electrophile and oxidant damage of mitochondrial DNA leading to rapid evolution of homoplasmic mutations
    • USA
    • Mambo, E., Gao, X., Cohen, Y., Guo, Z., Talalay, P. and Sidransky, D. (2003) Electrophile and oxidant damage of mitochondrial DNA leading to rapid evolution of homoplasmic mutations. Proc. Natl Acad. Sci. USA, 100, 1838-1843.
    • (2003) Proc. Natl Acad. Sci. , vol.100 , pp. 1838-1843
    • Mambo, E.1    Gao, X.2    Cohen, Y.3    Guo, Z.4    Talalay, P.5    Sidransky, D.6
  • 40
    • 61449091362 scopus 로고    scopus 로고
    • Mitochondrial DNA instability and metabolic shift in human cancers
    • Lee, H.C. and Wei, Y.H. (2009) Mitochondrial DNA instability and metabolic shift in human cancers. Int. J. Mol. Sci., 10, 674-701.
    • (2009) Int. J. Mol. Sci. , vol.10 , pp. 674-701
    • Lee, H.C.1    Wei, Y.H.2
  • 41
    • 0037314215 scopus 로고    scopus 로고
    • Neuronal degeneration and mitochondrial dysfunction
    • Schon, E.A. and Manfredi, G. (2003) Neuronal degeneration and mitochondrial dysfunction. J. Clin. Invest., 111, 303-312.
    • (2003) J. Clin. Invest. , vol.111 , pp. 303-312
    • Schon, E.A.1    Manfredi, G.2
  • 42
    • 0032247061 scopus 로고    scopus 로고
    • Smoking-associated mitochondrial DNA mutations and lipid peroxidation in human lung tissues
    • Fahn, H.J., Wang, L.S., Kao, S.H., Chang, S.C., Huang, M.H. and Wei, Y.H. (1998) Smoking-associated mitochondrial DNA mutations and lipid peroxidation in human lung tissues. Am. J. Resp. Cell Mol. Biol., 19, 901-909.
    • (1998) Am. J. Resp. Cell Mol. Biol. , vol.19 , pp. 901-909
    • Fahn, H.J.1    Wang, L.S.2    Kao, S.H.3    Chang, S.C.4    Huang, M.H.5    Wei, Y.H.6
  • 44
    • 0029121602 scopus 로고
    • Photoageing-associated mitochondrial DNA length mutations in human skin
    • Yang, J.H., Lee, H.C. and Wei, Y.H. (1995) Photoageing-associated mitochondrial DNA length mutations in human skin. Arch. Dermatol. Res., 287, 641-648.
    • (1995) Arch. Dermatol. Res. , vol.287 , pp. 641-648
    • Yang, J.H.1    Lee, H.C.2    Wei, Y.H.3
  • 45
    • 0036790385 scopus 로고    scopus 로고
    • Oxidative stress, mitochondrial DNA mutation, and impairment of antioxidant enzymes in aging
    • Wei, Y.H. and Lee, H.C. (2002) Oxidative stress, mitochondrial DNA mutation, and impairment of antioxidant enzymes in aging. Exp. Biol. Med., 227, 671-682.
    • (2002) Exp. Biol. Med. , vol.227 , pp. 671-682
    • Wei, Y.H.1    Lee, H.C.2
  • 46
    • 0033970827 scopus 로고    scopus 로고
    • The D-loop structure of human mtDNA is destabilized directly by 1-methyl-4-phenylpyridinium ion (MPP+), a parkinsonism-causing toxin
    • Umeda, S., Muta, T., Ohsato, T., Takamatsu, C., Hamasaki, N. and Kang, D. (2000) The D-loop structure of human mtDNA is destabilized directly by 1-methyl-4-phenylpyridinium ion (MPP+), a parkinsonism-causing toxin. Eur. J. Biochem./FEBS, 267, 200-206.
    • (2000) Eur. J. Biochem./FEBS , vol.267 , pp. 200-206
    • Umeda, S.1    Muta, T.2    Ohsato, T.3    Takamatsu, C.4    Hamasaki, N.5    Kang, D.6
  • 47


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