Altitude can alter the mtDNA copy number and nDNA integrity in sperm

Journal of Assisted Reproduction and Genetics

Volumn 28, Issue 10, 2011, Pages 951-956

  Luo, Yongjun ^a   Liao, Weigong ^a   Chen, Yu ^a   Cui, Jianhua ^b   Liu, Fuyu ^a   Jiang, Chunhua ^a   Gao, Wenxiang ^a   Gao, Yuqi ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b The 18th Hospital of PLA   (China)

Author keywords

Copy number; High altitude; Integrity; mtDNA; nDNA; Sperm

Indexed keywords

CELL NUCLEUS DNA; MITOCHONDRIAL DNA;

ADULT; ALTITUDE; ARTICLE; ASTHENOSPERMIA; DNA EXTRACTION; ENERGY YIELD; FLOW CYTOMETRY; GENE AMPLIFICATION; HUMAN; MALE; MALE INFERTILITY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SPERM; SPERMATOZOON; SPERMATOZOON MOTILITY;

ADOLESCENT; ADULT; ALTITUDE; DNA; DNA COPY NUMBER VARIATIONS; DNA DAMAGE; DNA, MITOCHONDRIAL; HUMANS; MALE; SEMEN ANALYSIS; SPERMATOZOA;

EID: 84355161716     PISSN: 10580468     EISSN: 15737330     Source Type: Journal    
DOI: 10.1007/s10815-011-9620-y     Document Type: Article

References (26)

1. E Ruiz-Pesini C Diez AC Lapena A Perez-Martos J Montoya E Alvarez, et al. 1998 Correlation of sperm motility with mitochondrial enzymatic activities Clin Chem 44 1616 1620 9702947 1:CAS:528:DyaK1cXltleltLg%3D (Pubitemid 28381202)
2. ML Pascual JA Cebrian-Perez MJ Lopez-Perez T Muino-Blanco 1996 Short-term inhibition of the energy metabolism affects motility but not surface properties of sperm cells Biosci Rep 16 35 40 8861538 10.1007/BF01200999 1:CAS:528:DyaK28XivV2ns7k%3D (Pubitemid 26160695)
3. K Nakada A Sato K Yoshida T Morita H Tanaka S Inoue, et al. 2006 Mitochondria-related male infertility Proc Natl Acad Sci U S A 103 15148 15153 17005726 10.1073/pnas.0604641103 1:CAS:528:DC%2BD28XhtFais7jP (Pubitemid 44583179)
4. C Diez-Sanchez E Ruiz-Pesini AC Lapena J Montoya A Perez-Martos JA Enriquez, et al. 2003 Mitochondrial DNA content of human spermatozoa Biol Reprod 68 180 185 12493711 10.1095/biolreprod.102.005140 1:CAS:528:DC%2BD3sXjtFSh (Pubitemid 36076334)
5. J Poulton K Morten C Freeman-Emmerson C Potter C Sewry V Dubowitz, et al. 1994 Deficiency of the human mitochondrial transcription factor h-mtTFA in infantile mitochondrial myopathy is associated with mtDNA depletion Hum Mol Genet 3 1763 1769 7849699 10.1093/hmg/3.10.1763 1:CAS:528:DyaK2cXmslersb0%3D (Pubitemid 24310468)
6. NG Larsson A Oldfors E Holme DA Clayton 1994 Low levels of mitochondrial transcription factor A in mitochondrial DNA depletion Biochem Biophys Res Commun 200 1374 1381 8185589 10.1006/bbrc.1994.1603 1:CAS:528:DyaK2cXkt1ynsb4%3D (Pubitemid 24181804)
7. CS Liu WL Cheng CF Lee YS Ma CY Lin CC Huang, et al. 2006 Alteration in the copy number of mitochondrial DNA in leukocytes of patients with mitochondrial encephalomyopathies Acta Neurol Scand 113 334 341 16629770 1:CAS:528:DC%2BD28Xkslensro%3D
8. GJ Song V Lewis 2008 Mitochondrial DNA integrity and copy number in sperm from infertile men Fertil Steril 90 2238 2244 18249386 10.1016/j.fertnstert. 2007.10.059 1:CAS:528:DC%2BD1MXmtlyjsg%3D%3D
9. S Kao HT Chao YH Wei 1995 Mitochondrial deoxyribonucleic acid 4977-bp deletion is associated with diminished fertility and motility of human sperm Biol Reprod 52 729 736 7779994 10.1095/biolreprod52.4.729 1:CAS:528: DyaK2MXksFWhtrc%3D
10. SH Kao HT Chao YH Wei 1998 Multiple deletions of mitochondrial DNA are associated with the decline of motility and fertility of human spermatozoa Mol Hum Reprod 4 657 666 9701788 10.1093/molehr/4.7.657 1:CAS:528:DyaK1cXlsVCgsb4%3D (Pubitemid 28372393)
11. AJ Holyoake P McHugh M Wu S O'Carroll P Benny IL Sin, et al. 2001 High incidence of single nucleotide substitutions in the mitochondrial genome is associated with poor semen parameters in men Int J Androl 24 175 182 11380706 10.1046/j.1365-2605.2001.00292.x 1:CAS:528:DC%2BD3MXktlyisLc%3D (Pubitemid 32476952)
12. J Spiropoulos DM Turnbull PF Chinnery 2002 Can mitochondrial DNA mutations cause sperm dysfunction? Mol Hum Reprod 8 719 721 12149402 10.1093/molehr/8.8.719 1:CAS:528:DC%2BD38XmvFOrsbw%3D
13. J Wang YY Lu 2009 Mitochondrial DNA 4977-bp deletion correlated with reactive oxygen species production and manganese superoxidedismutase expression in gastric tumor cells Chin Med J (Engl) 122 431 436 1:CAS:528: DC%2BD1MXjslOisb8%3D
14. JR Gosney 1984 Effects of hypobaric hypoxia on the Leydig cell population of the testis of the rat J Endocrinol 103 59 62 6481294 10.1677/joe.0.1030059 1:CAS:528:DyaL2cXls1yiu7o%3D (Pubitemid 14029044)
15. DK Saxena 1995 Effect of hypoxia by intermittent altitude exposure on semen characteristics and testicular morphology of male rhesus monkeys Int J Biometeorol 38 137 140 7744528 10.1007/BF01208490 1:STN:280:DyaK2M3mtlWqsA%3D%3D
16. A Okumura H Fuse Y Kawauchi I Mizuno T Akashi 2003 Changes in male reproductive function after high altitude mountaineering High Alt Med Biol 4 349 353 14561240 10.1089/152702903769192304 (Pubitemid 37259239)
17. V Verratti F Berardinelli C Di Giulio G Bosco M Cacchio M Pellicciotta, et al. 2008 Evidence that chronic hypoxia causes reversible impairment on male fertility Asian J Androl 10 602 606 18097511 10.1111/j.1745-7262.2008.00346.x (Pubitemid 351865766)
18. AT Rovio DR Marchington S Donat HC Schuppe J Abel E Fritsche, et al. 2001 Mutations at the mitochondrial DNA polymerase (POLG) locus associated with male infertility Nat Genet 29 261 262 11687794 10.1038/ng759 1:CAS:528: DC%2BD3MXotlWhsLo%3D (Pubitemid 33096448)
19. HC Lee YH Wei 2000 Mitochondrial role in life and death of the cell J Biomed Sci 7 2 15 10644884 10.1007/BF02255913 1:STN:280:DC%2BD3c7htlWhtg%3D%3D
20. EW Askew 2002 Work at high altitude and oxidative stress: antioxidant nutrients Toxicology 180 107 119 12324188 10.1016/S0300-483X(02)00385-2 1:CAS:528:DC%2BD38Xnt1Gjtbk%3D (Pubitemid 35254068)
21. A Hori M Yoshida T Shibata F Ling 2009 Reactive oxygen species regulate DNA copy number in isolated yeast mitochondria by triggering recombination-mediated replication Nucleic Acids Res 37 749 761 19074198 10.1093/nar/gkn993 1:CAS:528:DC%2BD1MXisFekt74%3D
22. MN Gadaleta G Rainaldi AM Lezza F Milella F Fracasso P Cantatore 1992 Mitochondrial DNA copy number and mitochondrial DNA deletion in adult and senescent rats Mutat Res 275 181 193 1383760 1:CAS:528:DyaK38XmsV2jtL8%3D
23. V Pesce A Cormio F Fracasso J Vecchiet G Felzani AM Lezza, et al. 2001 Age-related mitochondrial genotypic and phenotypic alterations in human skeletal muscle Free Radic Biol Med 30 1223 1233 11368920 10.1016/S0891-5849(01)00517-2 1:CAS:528:DC%2BD3MXjsFegt7s%3D (Pubitemid 32463933)
24. P May-Panloup MF Chretien F Savagner C Vasseur M Jean Y Malthiery, et al. 2003 Increased sperm mitochondrial DNA content in male infertility Hum Reprod 18 550 556 12615823 10.1093/humrep/deg096 1:CAS:528:DC%2BD3sXit1yrtb4%3D (Pubitemid 36329323)
25. A Zini MA Fischer S Sharir B Shayegan D Phang K Jarvi 2002 Prevalence of abnormal sperm DNA denaturation in fertile and infertile men Urology 60 1069 1072 12475672 10.1016/S0090-4295(02)01975-1 (Pubitemid 35447569)
26. LE Bennetts RJ Aitken 2005 A comparative study of oxidative DNA damage in mammalian spermatozoa Mol Reprod Dev 71 77 87 15736137 10.1002/mrd.20285 1:CAS:528:DC%2BD2MXjtVOqsrk%3D (Pubitemid 40471808)