-
1
-
-
12344305124
-
Mitochondrial dysfunction and type 2 diabetes
-
Lowell, B. B., and Shulman, G. I. (2005) Mitochondrial dysfunction and type 2 diabetes. Science 307, 384-387
-
(2005)
Science
, vol.307
, pp. 384-387
-
-
Lowell, B.B.1
Shulman, G.I.2
-
2
-
-
23844558266
-
Amitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: A dawn for evolutionary medicine
-
Wallace, D. C. (2005) Amitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine. Annu. Rev. Genet. 39, 359-407
-
(2005)
Annu. Rev. Genet.
, vol.39
, pp. 359-407
-
-
Wallace, D.C.1
-
3
-
-
0034643340
-
Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage
-
Nishikawa, T., Edelstein, D., Du, X.L., Yamagishi, S., Matsumura, T., Kaneda, Y., Yorek, M. A., Beebe, D., Oates, P. J., Hammes, H. P., Giardino, I., and Brownlee, M. (2000) Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage. Nature 404, 787-790
-
(2000)
Nature
, vol.404
, pp. 787-790
-
-
Nishikawa, T.1
Edelstein, D.2
Du, X.L.3
Yamagishi, S.4
Matsumura, T.5
Kaneda, Y.6
Yorek, M.A.7
Beebe, D.8
Oates, P.J.9
Hammes, H.P.10
Giardino, I.11
Brownlee, M.12
-
4
-
-
84897529482
-
Targeting mitochondria as therapeutic strategy for metabolic disorders
-
Sorriento, D., Pascale, A.V., Finelli, R., Carillo, A.L., Annunziata, R., Trimarco, B., and Iaccarino, G. (2014) Targeting mitochondria as therapeutic strategy for metabolic disorders. Scientific World Journal 2014, 604685
-
(2014)
Scientific World Journal
, vol.2014
, pp. 604685
-
-
Sorriento, D.1
Pascale, A.V.2
Finelli, R.3
Carillo, A.L.4
Annunziata, R.5
Trimarco, B.6
Iaccarino, G.7
-
5
-
-
33746016268
-
Mitochondria: More than just a powerhouse
-
McBride, H.M., Neuspiel, M., and Wasiak, S. (2006) Mitochondria: more than just a powerhouse. Curr. Biol. 16, R551-R560
-
(2006)
Curr. Biol.
, vol.16
, pp. R551-R560
-
-
McBride, H.M.1
Neuspiel, M.2
Wasiak, S.3
-
6
-
-
84911406648
-
Mitochondrial protein import under kinase surveillance
-
Opalinska, M., and Meisinger, C. (2014) Mitochondrial protein import under kinase surveillance. Microb. Cell 1, 51-57
-
(2014)
Microb. Cell
, vol.1
, pp. 51-57
-
-
Opalinska, M.1
Meisinger, C.2
-
7
-
-
30944449043
-
Mitochondrial modulation: Reversible phosphorylation takes center stage?
-
Pagliarini, D. J., and Dixon, J. E. (2006) Mitochondrial modulation: reversible phosphorylation takes center stage? Trends Biochem. Sci. 31, 26-34
-
(2006)
Trends Biochem. Sci.
, vol.31
, pp. 26-34
-
-
Pagliarini, D.J.1
Dixon, J.E.2
-
8
-
-
84878531701
-
CAMP and mitochondria
-
Valsecchi, F., Ramos-Espiritu, L. S., Buck, J., Levin, L. R., and Manfredi, G. (2013) cAMP and mitochondria. Physiology (Bethesda) 28, 199-209
-
(2013)
Physiology (Bethesda)
, vol.28
, pp. 199-209
-
-
Valsecchi, F.1
Ramos-Espiritu, L.S.2
Buck, J.3
Levin, L.R.4
Manfredi, G.5
-
9
-
-
60649095658
-
Cyclic AMP produced inside mitochondria regulates oxidative phosphorylation
-
Acin-Perez, R., Salazar, E., Kamenetsky, M., Buck, J., Levin, L. R., and Manfredi, G. (2009) Cyclic AMP produced inside mitochondria regulates oxidative phosphorylation. Cell Metab. 9, 265-276
-
(2009)
Cell Metab.
, vol.9
, pp. 265-276
-
-
Acin-Perez, R.1
Salazar, E.2
Kamenetsky, M.3
Buck, J.4
Levin, L.R.5
Manfredi, G.6
-
10
-
-
76149121171
-
Control of oxidative phosphorylation by Vitamin A illuminates a fundamental role in mitochondrial energy homoeostasis
-
Acin-Perez, R., Hoyos, B., Zhao, F., Vinogradov, V., Fischman, D. A., Harris, R. A., Leitges, M., Wongsiriroy, N., Blaner, W. S., Manfredi, G., and Hammerling, U. (2010) Control of oxidative phosphorylation by vitamin A illuminates a fundamental role in mitochondrial energy homoeostasis. FASEB J. 24, 627-636
-
(2010)
FASEB J.
, vol.24
, pp. 627-636
-
-
Acin-Perez, R.1
Hoyos, B.2
Zhao, F.3
Vinogradov, V.4
Fischman, D.A.5
Harris, R.A.6
Leitges, M.7
Wongsiriroy, N.8
Blaner, W.S.9
Manfredi, G.10
Hammerling, U.11
-
11
-
-
78649734511
-
Regulation of intermediary metabolism by the PKCdelta signalosome in mitochondria
-
Acin-Perez, R., Hoyos, B., Gong, J., Vinogradov, V., Fischman, D. A., Leitges, M., Borhan, B., Starkov, A., Manfredi, G., and Hammerling, U. (2010) Regulation of intermediary metabolism by the PKCdelta signalosome in mitochondria. FASEB J. 24, 5033-5042
-
(2010)
FASEB J.
, vol.24
, pp. 5033-5042
-
-
Acin-Perez, R.1
Hoyos, B.2
Gong, J.3
Vinogradov, V.4
Fischman, D.A.5
Leitges, M.6
Borhan, B.7
Starkov, A.8
Manfredi, G.9
Hammerling, U.10
-
12
-
-
79551674547
-
Are zinc-finger domains of protein kinase C dynamic structures that unfold by lipid or redox activation?
-
Zhao, F., Ilbert, M., Varadan, R., Cremers, C. M., Hoyos, B., Acin-Perez, R., Vinogradov, V., Cowburn, D., Jakob, U., and Hammerling, U. (2011) Are zinc-finger domains of protein kinase C dynamic structures that unfold by lipid or redox activation? Antioxid. Redox Signal. 14, 757-766
-
(2011)
Antioxid. Redox Signal.
, vol.14
, pp. 757-766
-
-
Zhao, F.1
Ilbert, M.2
Varadan, R.3
Cremers, C.M.4
Hoyos, B.5
Acin-Perez, R.6
Vinogradov, V.7
Cowburn, D.8
Jakob, U.9
Hammerling, U.10
-
13
-
-
0030764985
-
Activation of proteinkinaseC by tyrosine phosphorylation in response to H2O2
-
Konishi, H., Tanaka, M., Takemura, Y., Matsuzaki, H., Ono, Y., Kikkawa, U., and Nishizuka, Y. (1997) Activation of proteinkinaseC by tyrosine phosphorylation in response to H2O2. Proc. Natl. Acad. Sci. USA 94, 11233-11237
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 11233-11237
-
-
Konishi, H.1
Tanaka, M.2
Takemura, Y.3
Matsuzaki, H.4
Ono, Y.5
Kikkawa, U.6
Nishizuka, Y.7
-
14
-
-
0037113925
-
Zinc release from protein kinase C as the common event during activation by lipid second messenger or reactive oxygen
-
Korichneva, I., Hoyos, B., Chua, R., Levi, E., and Hammerling, U. (2002) Zinc release from protein kinase C as the common event during activation by lipid second messenger or reactive oxygen. J. Biol. Chem. 277, 44327-44331
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 44327-44331
-
-
Korichneva, I.1
Hoyos, B.2
Chua, R.3
Levi, E.4
Hammerling, U.5
-
15
-
-
83255185121
-
Hiding in plain sight: Uncovering a new function of Vitamin A in redox signaling
-
Hoyos, B., Acin-Perez, R., Fischman, D. A., Manfredi, G., and Hammerling, U. (2012) Hiding in plain sight: uncovering a new function of vitamin A in redox signaling. Biochim. Biophys. Acta 1821, 241-247
-
(2012)
Biochim. Biophys. Acta
, vol.1821
, pp. 241-247
-
-
Hoyos, B.1
Acin-Perez, R.2
Fischman, D.A.3
Manfredi, G.4
Hammerling, U.5
-
16
-
-
84885100122
-
The centennial of Vitamin A: A century of research in retinoids and carotenoids
-
Hammerling, U. (2013) The centennial of vitamin A: a century of research in retinoids and carotenoids. FASEB J. 27, 3887-3890
-
(2013)
FASEB J.
, vol.27
, pp. 3887-3890
-
-
Hammerling, U.1
-
17
-
-
0025286082
-
Retinol is essential for growth of activated human B cells
-
Buck, J., Ritter, G., Dannecker, L., Katta, V., Cohen, S. L., Chait, B. T., and Hämmerling, U. (1990) Retinol is essential for growth of activated human B cells. J. Exp. Med. 171, 1613-1624
-
(1990)
J. Exp. Med.
, vol.171
, pp. 1613-1624
-
-
Buck, J.1
Ritter, G.2
Dannecker, L.3
Katta, V.4
Cohen, S.L.5
Chait, B.T.6
Hämmerling, U.7
-
18
-
-
0026357656
-
Intracellular signaling by 14-hydroxy-4,14-retro-retinol
-
Buck, J., Derguini, F., Levi, E., Nakanishi, K., and Hämmerling, U. (1991) Intracellular signaling by 14-hydroxy-4,14-retro-retinol. Science 254, 1654-1656
-
(1991)
Science
, vol.254
, pp. 1654-1656
-
-
Buck, J.1
Derguini, F.2
Levi, E.3
Nakanishi, K.4
Hämmerling, U.5
-
19
-
-
55549139488
-
Vitamin A depletion causes oxidative stress, mitochondrial dysfunction, and PARP-1-dependent energy deprivation
-
Chiu, H.-J., Fischman, D. A., and Hammerling, U. (2008) Vitamin A depletion causes oxidative stress, mitochondrial dysfunction, and PARP-1-dependent energy deprivation. FASEB J. 22, 3878-3887
-
(2008)
FASEB J.
, vol.22
, pp. 3878-3887
-
-
Chiu, H.-J.1
Fischman, D.A.2
Hammerling, U.3
-
20
-
-
79952047543
-
Vitamin A metabolism: An update
-
D'Ambrosio, D. N., Clugston, R. D., and Blaner, W. S. (2011) Vitamin A metabolism: an update. Nutrients 3, 63-103
-
(2011)
Nutrients
, vol.3
, pp. 63-103
-
-
D'Ambrosio, D.N.1
Clugston, R.D.2
Blaner, W.S.3
-
21
-
-
0037119413
-
Muscle expression of humanretinol-binding protein(RBP). Suppression of the visual defect of RBP knockoutmice
-
Quadro, L., Blaner, W. S., Hamberger, L., VanGelder, R. N., Vogel, S., Piantedosi, R., Gouras, P., Colantuoni, V., and Gottesman, M.E. (2002) Muscle expression of humanretinol-binding protein(RBP). Suppression of the visual defect of RBP knockoutmice. J. Biol. Chem. 277, 30191-30197
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 30191-30197
-
-
Quadro, L.1
Blaner, W.S.2
Hamberger, L.3
VanGelder, R.N.4
Vogel, S.5
Piantedosi, R.6
Gouras, P.7
Colantuoni, V.8
Gottesman, M.E.9
-
22
-
-
22944434929
-
Serumretinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes
-
Yang, Q., Graham, T. E., Mody, N., Preitner, F., Peroni, O. D., Zabolotny, J. M., Kotani, K., Quadro, L., and Kahn, B. B. (2005) Serumretinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes. Nature 436, 356-362
-
(2005)
Nature
, vol.436
, pp. 356-362
-
-
Yang, Q.1
Graham, T.E.2
Mody, N.3
Preitner, F.4
Peroni, O.D.5
Zabolotny, J.M.6
Kotani, K.7
Quadro, L.8
Kahn, B.B.9
-
23
-
-
84895741552
-
RBP4 activates antigen-presenting cells, leading to adipose tissue inflammation and systemic insulin resistance
-
Moraes-Vieira, P. M., Yore, M. M., Dwyer, P. M., Syed, I., Aryal, P., and Kahn, B. B. (2014) RBP4 activates antigen-presenting cells, leading to adipose tissue inflammation and systemic insulin resistance. Cell Metab. 19, 512-526
-
(2014)
Cell Metab.
, vol.19
, pp. 512-526
-
-
Moraes-Vieira, P.M.1
Yore, M.M.2
Dwyer, P.M.3
Syed, I.4
Aryal, P.5
Kahn, B.B.6
-
24
-
-
33750851422
-
Retinol-bindingprotein4 in human obesity
-
Janke, J., Engeli, S., Boschmann, M., Adams, F., Böhnke, J., Luft, F.C., Sharma, A.M., and Jordan, J. (2006) Retinol-bindingprotein4 in human obesity. Diabetes 55, 2805-2810
-
(2006)
Diabetes
, vol.55
, pp. 2805-2810
-
-
Janke, J.1
Engeli, S.2
Boschmann, M.3
Adams, F.4
Böhnke, J.5
Luft, F.C.6
Sharma, A.M.7
Jordan, J.8
-
25
-
-
34447130277
-
Editorial: Retinol binding protein 4 and pathogenesis of diabetes
-
McTernan, P. G., and Kumar, S. (2007) Editorial: Retinol binding protein 4 and pathogenesis of diabetes. J. Clin. Endocrinol. Metab. 92, 2430-2432
-
(2007)
J. Clin. Endocrinol. Metab.
, vol.92
, pp. 2430-2432
-
-
McTernan, P.G.1
Kumar, S.2
-
26
-
-
65549121651
-
Identification and characterization of a non-retinoid ligand for retinol-binding protein 4 which lowers serum retinol-binding protein 4 levels in vivo
-
Motani, A., Wang, Z., Conn, M., Siegler, K., Zhang, Y., Liu, Q., Johnstone, S., Xu, H., Thibault, S., Wang, Y., Fan, P., Connors, R., Le, H., Xu, G., Walker, N., Shan, B., and Coward, P. (2009) Identification and characterization of a non-retinoid ligand for retinol-binding protein 4 which lowers serum retinol-binding protein 4 levels in vivo. J. Biol. Chem. 284, 7673-7680
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 7673-7680
-
-
Motani, A.1
Wang, Z.2
Conn, M.3
Siegler, K.4
Zhang, Y.5
Liu, Q.6
Johnstone, S.7
Xu, H.8
Thibault, S.9
Wang, Y.10
Fan, P.11
Connors, R.12
Le, H.13
Xu, G.14
Walker, N.15
Shan, B.16
Coward, P.17
-
27
-
-
33845479911
-
Plasma retinol-binding protein-4 concentrations are elevated in human subjects with impaired glucose tolerance and type 2 diabetes
-
Cho, Y. M., Youn, B. S., Lee, H., Lee, N., Min, S. S., Kwak, S. H., Lee, H. K., and Park, K. S. (2006) Plasma retinol-binding protein-4 concentrations are elevated in human subjects with impaired glucose tolerance and type 2 diabetes. Diabetes Care 29, 2457-2461
-
(2006)
Diabetes Care
, vol.29
, pp. 2457-2461
-
-
Cho, Y.M.1
Youn, B.S.2
Lee, H.3
Lee, N.4
Min, S.S.5
Kwak, S.H.6
Lee, H.K.7
Park, K.S.8
-
28
-
-
33745095399
-
Retinol-binding protein 4 and insulin resistance in lean, obese, and diabetic subjects
-
Graham, T. E., Yang, Q., Blüher, M., Hammarstedt, A., Ciaraldi, T. P., Henry, R. R., Wason, C. J., Oberbach, A., Jansson, P. A., Smith, U., and Kahn, B. B. (2006) Retinol-binding protein 4 and insulin resistance in lean, obese, and diabetic subjects. N. Engl. J. Med. 354, 2552-2563
-
(2006)
N. Engl. J. Med.
, vol.354
, pp. 2552-2563
-
-
Graham, T.E.1
Yang, Q.2
Blüher, M.3
Hammarstedt, A.4
Ciaraldi, T.P.5
Henry, R.R.6
Wason, C.J.7
Oberbach, A.8
Jansson, P.A.9
Smith, U.10
Kahn, B.B.11
-
29
-
-
34249860936
-
Retinol-binding protein 4 is associated with insulin resistance and body fat distribution in nonobese subjects without type 2 diabetes
-
Gavi, S., Stuart, L. M., Kelly, P., Melendez, M. M., Mynarcik, D. C., Gelato, M. C., and McNurlan, M.A. (2007) Retinol-binding protein 4 is associated with insulin resistance and body fat distribution in nonobese subjects without type 2 diabetes. J. Clin. Endocrinol. Metab. 92, 1886-1890
-
(2007)
J. Clin. Endocrinol. Metab.
, vol.92
, pp. 1886-1890
-
-
Gavi, S.1
Stuart, L.M.2
Kelly, P.3
Melendez, M.M.4
Mynarcik, D.C.5
Gelato, M.C.6
McNurlan, M.A.7
-
30
-
-
34547787736
-
Association of serum retinol-binding protein 4 and visceral adiposity in Chinese subjects with and without type 2 diabetes
-
Jia, W., Wu, H., Bao, Y., Wang, C., Lu, J., Zhu, J., and Xiang, K. (2007) Association of serum retinol-binding protein 4 and visceral adiposity in Chinese subjects with and without type 2 diabetes. J. Clin. Endocrinol. Metab. 92, 3224-3229
-
(2007)
J. Clin. Endocrinol. Metab.
, vol.92
, pp. 3224-3229
-
-
Jia, W.1
Wu, H.2
Bao, Y.3
Wang, C.4
Lu, J.5
Zhu, J.6
Xiang, K.7
-
31
-
-
72249122097
-
Long-term Fenretinide treatment prevents high-fat dietinduced obesity, insulin resistance, and hepatic steatosis
-
Preitner, F., Mody, N., Graham, T. E., Peroni, O. D., and Kahn, B. B. (2009) Long-term Fenretinide treatment prevents high-fat dietinduced obesity, insulin resistance, and hepatic steatosis. Am. J. Physiol. Endocrinol. Metab. 297, E1420-E1429
-
(2009)
Am. J. Physiol. Endocrinol. Metab.
, vol.297
, pp. E1420-E1429
-
-
Preitner, F.1
Mody, N.2
Graham, T.E.3
Peroni, O.D.4
Kahn, B.B.5
-
32
-
-
74949100673
-
All-trans retinoic acid lowers serum retinol-binding protein 4 concentrations and increases insulin sensitivity in diabetic mice
-
Manolescu, D. C., Sima, A., and Bhat, P. V. (2010) All-trans retinoic acid lowers serum retinol-binding protein 4 concentrations and increases insulin sensitivity in diabetic mice. J. Nutr. 140, 311-316
-
(2010)
J. Nutr.
, vol.140
, pp. 311-316
-
-
Manolescu, D.C.1
Sima, A.2
Bhat, P.V.3
-
33
-
-
84861403641
-
Retinolbinding protein 4 inhibits insulin signaling in adipocytes by inducing proinflammatory cytokines inmacrophages througha c-Jun N-terminal kinase- and toll-like receptor 4-dependent and retinolindependent mechanism
-
Norseen, J., Hosooka, T., Hammarstedt, A., Yore, M. M., Kant, S., Aryal, P., Kiernan, U. A., Phillips, D. A., Maruyama, H., Kraus, B. J., Usheva, A., Davis, R. J., Smith, U., and Kahn, B. B. (2012) Retinolbinding protein 4 inhibits insulin signaling in adipocytes by inducing proinflammatory cytokines inmacrophages througha c-Jun N-terminal kinase- and toll-like receptor 4-dependent and retinolindependent mechanism. Mol. Cell. Biol. 32, 2010-2019
-
(2012)
Mol. Cell. Biol.
, vol.32
, pp. 2010-2019
-
-
Norseen, J.1
Hosooka, T.2
Hammarstedt, A.3
Yore, M.M.4
Kant, S.5
Aryal, P.6
Kiernan, U.A.7
Phillips, D.A.8
Maruyama, H.9
Kraus, B.J.10
Usheva, A.11
Davis, R.J.12
Smith, U.13
Kahn, B.B.14
-
34
-
-
79952734461
-
Signaling by Vitamin A and retinol-binding protein regulates gene expression to inhibit insulin responses
-
Berry, D. C., Jin, H., Majumdar, A., and Noy, N. (2011) Signaling by vitamin A and retinol-binding protein regulates gene expression to inhibit insulin responses. Proc. Natl. Acad. Sci. USA 108, 4340-4345
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 4340-4345
-
-
Berry, D.C.1
Jin, H.2
Majumdar, A.3
Noy, N.4
-
35
-
-
84883171546
-
The STRA6 receptor is essential for retinol-binding protein-induced insulin resistance but not for maintaining Vitamin A homeostasis in tissues other than the eye
-
Berry, D. C., Jacobs, H., Marwarha, G., Gely-Pernot, A., O'Byrne, S. M., DeSantis, D., Klopfenstein, M., Feret, B., Dennefeld, C., Blaner, W. S., Croniger, C. M., Mark, M., Noy, N., and Ghyselinck, N. B. (2013) The STRA6 receptor is essential for retinol-binding protein-induced insulin resistance but not for maintaining vitamin A homeostasis in tissues other than the eye. J. Biol. Chem. 288, 24528-24539
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 24528-24539
-
-
Berry, D.C.1
Jacobs, H.2
Marwarha, G.3
Gely-Pernot, A.4
O'Byrne, S.M.5
DeSantis, D.6
Klopfenstein, M.7
Feret, B.8
Dennefeld, C.9
Blaner, W.S.10
Croniger, C.M.11
Mark, M.12
Noy, N.13
Ghyselinck, N.B.14
-
36
-
-
48249089367
-
Protein kinase C function in muscle, liver, and beta-cells and its therapeutic implications for type 2 diabetes
-
Schmitz-Peiffer, C., and Biden, T. J. (2008) Protein kinase C function in muscle, liver, and beta-cells and its therapeutic implications for type 2 diabetes. Diabetes 57, 1774-1783
-
(2008)
Diabetes
, vol.57
, pp. 1774-1783
-
-
Schmitz-Peiffer, C.1
Biden, T.J.2
-
37
-
-
79957885392
-
PKCδ regulates hepatic insulin sensitivity and hepatosteatosis in mice and humans
-
Bezy, O., Tran, T. T., Pihlajamäki, J., Suzuki, R., Emanuelli, B., Winnay, J., Mori, M. A., Haas, J., Biddinger, S. B., Leitges, M., Goldfine, A. B., Patti, M. E., King, G. L., and Kahn, C. R. (2011) PKCδ regulates hepatic insulin sensitivity and hepatosteatosis in mice and humans. J. Clin. Invest. 121, 2504-2517
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 2504-2517
-
-
Bezy, O.1
Tran, T.T.2
Pihlajamäki, J.3
Suzuki, R.4
Emanuelli, B.5
Winnay, J.6
Mori, M.A.7
Haas, J.8
Biddinger, S.B.9
Leitges, M.10
Goldfine, A.B.11
Patti, M.E.12
King, G.L.13
Kahn, C.R.14
-
38
-
-
0035179086
-
Exacerbated vein graft arteriosclerosis in protein kinase Cdeltanull mice
-
Leitges, M., Mayr, M., Braun, U., Mayr, U., Li, C., Pfister, G., Ghaffari-Tabrizi, N., Baier, G., Hu, Y., and Xu, Q. (2001) Exacerbated vein graft arteriosclerosis in protein kinase Cdeltanull mice. J. Clin. Invest. 108, 1505-1512
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 1505-1512
-
-
Leitges, M.1
Mayr, M.2
Braun, U.3
Mayr, U.4
Li, C.5
Pfister, G.6
Ghaffari-Tabrizi, N.7
Baier, G.8
Hu, Y.9
Xu, Q.10
-
39
-
-
0033922371
-
Preparation of PCR-quality mouse genomic DNA with hot sodium hydroxide and tris (HotSHOT)
-
Truett, G. E., Heeger, P., Mynatt, R. L., Truett, A. A., Walker, J. A., and Warman, M. L. (2000) Preparation of PCR-quality mouse genomic DNA with hot sodium hydroxide and tris (HotSHOT). Biotechniques 29, 52
-
(2000)
Biotechniques
, vol.29
, pp. 52
-
-
Truett, G.E.1
Heeger, P.2
Mynatt, R.L.3
Truett, A.A.4
Walker, J.A.5
Warman, M.L.6
-
40
-
-
70449158340
-
A simple method for the isolation and purification of total lipides from animal tissues
-
Folch, J., Lees, M., and Sloane Stanley, G. H. (1957) A simple method for the isolation and purification of total lipides from animal tissues. J. Biol. Chem. 226, 497-509
-
(1957)
J. Biol. Chem.
, vol.226
, pp. 497-509
-
-
Folch, J.1
Lees, M.2
Sloane Stanley, G.H.3
-
41
-
-
3543028031
-
Abnormal cardiac development in the absence of heart glycogen
-
Pederson, B. A., Chen, H., Schroeder, J. M., Shou, W., DePaoli-Roach, A. A., and Roach, P. J. (2004) Abnormal cardiac development in the absence of heart glycogen. Mol. Cell. Biol. 24, 7179-7187
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 7179-7187
-
-
Pederson, B.A.1
Chen, H.2
Schroeder, J.M.3
Shou, W.4
DePaoli-Roach, A.A.5
Roach, P.J.6
-
42
-
-
0032190022
-
Recombinant human retinol-binding protein refolding, native disulfide formation, and characterization
-
Xie, Y., Lashuel, H.A., Miroy, G. J., Dikler, S., and Kelly, J.W. (1998) Recombinant human retinol-binding protein refolding, native disulfide formation, and characterization. Protein Expr. Purif. 14, 31-37
-
(1998)
Protein Expr. Purif.
, vol.14
, pp. 31-37
-
-
Xie, Y.1
Lashuel, H.A.2
Miroy, G.J.3
Dikler, S.4
Kelly, J.W.5
-
44
-
-
84976998771
-
The application of electronic computers to factor analysis
-
Kaiser, H. F. (1960) The application of electronic computers to factor analysis. Educ. Psychol. Meas. 20, 141-151
-
(1960)
Educ. Psychol. Meas.
, vol.20
, pp. 141-151
-
-
Kaiser, H.F.1
-
45
-
-
34047261439
-
Protein kinase Cdelta plays a non-redundant role in insulin secretion in pancreatic beta cells
-
Uchida, T., Iwashita, N., Ohara-Imaizumi, M., Ogihara, T., Nagai, S., Choi, J. B., Tamura, Y., Tada, N., Kawamori, R., Nakayama, K. I., Nagamatsu, S., and Watada, H. (2007) Protein kinase Cdelta plays a non-redundant role in insulin secretion in pancreatic beta cells. J. Biol. Chem. 282, 2707-2716
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 2707-2716
-
-
Uchida, T.1
Iwashita, N.2
Ohara-Imaizumi, M.3
Ogihara, T.4
Nagai, S.5
Choi, J.B.6
Tamura, Y.7
Tada, N.8
Kawamori, R.9
Nakayama, K.I.10
Nagamatsu, S.11
Watada, H.12
-
46
-
-
0016309270
-
Selection for growth rate, feed efficiency and body composition in mice
-
Sutherland, T.M., Biondini, P.E., and Ward, G.M. (1974) Selection for growth rate, feed efficiency and body composition in mice. Genetics 78, 525-540
-
(1974)
Genetics
, vol.78
, pp. 525-540
-
-
Sutherland, T.M.1
Biondini, P.E.2
Ward, G.M.3
-
47
-
-
0028338707
-
Tumor necrosis factor alpha is an autocrine growth factor for normal human B cells
-
Boussiotis, V.A., Nadler, L.M., Strominger, J. L., and Goldfeld, A. E. (1994) Tumor necrosis factor alpha is an autocrine growth factor for normal human B cells. Proc. Natl. Acad. Sci. USA 91, 7007-7011
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 7007-7011
-
-
Boussiotis, V.A.1
Nadler, L.M.2
Strominger, J.L.3
Goldfeld, A.E.4
-
48
-
-
0037171731
-
Increased proliferation of B cells and autoimmunity in mice lacking protein kinase Cdelta
-
Miyamoto, A., Nakayama, K., Imaki, H., Hirose, S., Jiang, Y., Abe, M., Tsukiyama, T., Nagahama, H., Ohno, S., Hatakeyama, S., and Nakayama, K. I. (2002) Increased proliferation of B cells and autoimmunity in mice lacking protein kinase Cdelta. Nature 416, 865-869
-
(2002)
Nature
, vol.416
, pp. 865-869
-
-
Miyamoto, A.1
Nakayama, K.2
Imaki, H.3
Hirose, S.4
Jiang, Y.5
Abe, M.6
Tsukiyama, T.7
Nagahama, H.8
Ohno, S.9
Hatakeyama, S.10
Nakayama, K.I.11
-
49
-
-
84879132077
-
Loss-of-function of the protein kinase C δ (PKCδ) causes a B-cell lymphoproliferative syndrome in humans
-
Kuehn, H. S., Niemela, J.E., Rangel-Santos, A., Zhang, M., Pittaluga, S., Stoddard, J. L., Hussey, A. A., Evbuomwan, M. O., Priel, D. A., Kuhns, D.B., Park, C. L., Fleisher, T. A., Uzel, G., and Oliveira, J.B. (2013) Loss-of-function of the protein kinase C δ (PKCδ) causes a B-cell lymphoproliferative syndrome in humans. Blood 121, 3117-3125
-
(2013)
Blood
, vol.121
, pp. 3117-3125
-
-
Kuehn, H.S.1
Niemela, J.E.2
Rangel-Santos, A.3
Zhang, M.4
Pittaluga, S.5
Stoddard, J.L.6
Hussey, A.A.7
Evbuomwan, M.O.8
Priel, D.A.9
Kuhns, D.B.10
Park, C.L.11
Fleisher, T.A.12
Uzel, G.13
Oliveira, J.B.14
-
50
-
-
3843117675
-
Retinoid X receptor gamma-deficient mice have increased skeletal muscle lipoprotein lipase activity and less weight gain when fed a high-fat diet
-
Haugen, B. R., Jensen, D. R., Sharma, V., Pulawa, L. K., Hays, W. R., Krezel, W., Chambon, P., and Eckel, R. H. (2004) Retinoid X receptor gamma-deficient mice have increased skeletal muscle lipoprotein lipase activity and less weight gain when fed a high-fat diet. Endocrinology 145, 3679-3685
-
(2004)
Endocrinology
, vol.145
, pp. 3679-3685
-
-
Haugen, B.R.1
Jensen, D.R.2
Sharma, V.3
Pulawa, L.K.4
Hays, W.R.5
Krezel, W.6
Chambon, P.7
Eckel, R.H.8
-
52
-
-
35348992350
-
Secrets of the lac operon. Glucose hysteresis as a mechanismin dietary restriction, aging and disease
-
Mobbs, C. V., Mastaitis, J. W., Zhang, M., Isoda, F., Cheng, H., and Yen, K. (2007) Secrets of the lac operon. Glucose hysteresis as a mechanismin dietary restriction, aging and disease. Interdiscip. Top. Gerontol. 35, 39-68
-
(2007)
Interdiscip. Top. Gerontol.
, vol.35
, pp. 39-68
-
-
Mobbs, C.V.1
Mastaitis, J.W.2
Zhang, M.3
Isoda, F.4
Cheng, H.5
Yen, K.6
-
53
-
-
84922709227
-
Hepatic acetyl CoA links adipose tissue inflammation to hepatic insulin resistance and type 2 diabetes
-
Perry, R. J., Camporez, J. P., Kursawe, R., Titchenell, P.M., Zhang, D., Perry, C. J., Jurczak, M. J., Abudukadier, A., Han, M. S., Zhang, X. M., Ruan, H. B., Yang, X., Caprio, S., Kaech, S. M., Sul, H. S., Birnbaum, M. J., Davis, R. J., Cline, G. W., Petersen, K. F., and Shulman, G. I. (2015) Hepatic acetyl CoA links adipose tissue inflammation to hepatic insulin resistance and type 2 diabetes. Cell 160, 745-758
-
(2015)
Cell
, vol.160
, pp. 745-758
-
-
Perry, R.J.1
Camporez, J.P.2
Kursawe, R.3
Titchenell, P.M.4
Zhang, D.5
Perry, C.J.6
Jurczak, M.J.7
Abudukadier, A.8
Han, M.S.9
Zhang, X.M.10
Ruan, H.B.11
Yang, X.12
Caprio, S.13
Kaech, S.M.14
Sul, H.S.15
Birnbaum, M.J.16
Davis, R.J.17
Cline, G.W.18
Petersen, K.F.19
Shulman, G.I.20
more..
-
54
-
-
38649116056
-
Selective versus total insulin resistance: A pathogenic paradox
-
Brown, M. S., and Goldstein, J. L. (2008) Selective versus total insulin resistance: a pathogenic paradox. Cell Metab. 7, 95-96
-
(2008)
Cell Metab.
, vol.7
, pp. 95-96
-
-
Brown, M.S.1
Goldstein, J.L.2
-
55
-
-
0035062765
-
Insulin induces specific interaction between insulin receptor and protein kinase C delta in primary cultured skeletal muscle
-
Braiman, L., Alt, A., Kuroki, T., Ohba, M., Bak, A., Tennenbaum, T., and Sampson, S. R. (2001) Insulin induces specific interaction between insulin receptor and protein kinase C delta in primary cultured skeletal muscle. Mol. Endocrinol. 15, 565-574
-
(2001)
Mol. Endocrinol.
, vol.15
, pp. 565-574
-
-
Braiman, L.1
Alt, A.2
Kuroki, T.3
Ohba, M.4
Bak, A.5
Tennenbaum, T.6
Sampson, S.R.7
-
56
-
-
33748617142
-
PKCdelta-mediated IRS-1 Ser24 phosphorylation negatively regulates IRS-1 function
-
Greene, M. W., Ruhoff, M. S., Roth, R. A., Kim, J.A., Quon, M. J., and Krause, J. A. (2006) PKCdelta-mediated IRS-1 Ser24 phosphorylation negatively regulates IRS-1 function. Biochem. Biophys. Res. Commun. 349, 976-986
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.349
, pp. 976-986
-
-
Greene, M.W.1
Ruhoff, M.S.2
Roth, R.A.3
Kim, J.A.4
Quon, M.J.5
Krause, J.A.6
-
57
-
-
0035085644
-
Control of glycogen synthesis by glucose, glycogen, and insulin in cultured human muscle cells
-
Halse, R., Bonavaud, S.M., Armstrong, J. L., McCormack, J.G., and Yeaman, S. J. (2001) Control of glycogen synthesis by glucose, glycogen, and insulin in cultured human muscle cells. Diabetes 50, 720-726
-
(2001)
Diabetes
, vol.50
, pp. 720-726
-
-
Halse, R.1
Bonavaud, S.M.2
Armstrong, J.L.3
McCormack, J.G.4
Yeaman, S.J.5
-
58
-
-
9444262473
-
Alterations in postprandial hepatic glycogen metabolism in type 2 diabetes
-
Krssak, M., Brehm, A., Bernroider, E., Anderwald, C., Nowotny, P., Dalla Man, C., Cobelli, C., Cline, G. W., Shulman, G. I., Waldhäusl, W., and Roden, M. (2004) Alterations in postprandial hepatic glycogen metabolism in type 2 diabetes. Diabetes 53, 3048-3056
-
(2004)
Diabetes
, vol.53
, pp. 3048-3056
-
-
Krssak, M.1
Brehm, A.2
Bernroider, E.3
Anderwald, C.4
Nowotny, P.5
Dalla Man, C.6
Cobelli, C.7
Cline, G.W.8
Shulman, G.I.9
Waldhäusl, W.10
Roden, M.11
-
59
-
-
0036083834
-
Gene expression profile of rat adipose tissue at the onset of high-fat-diet obesity
-
Li, J., Yu, X., Pan, W., and Unger, R. H. (2002) Gene expression profile of rat adipose tissue at the onset of high-fat-diet obesity. Am. J. Physiol. Endocrinol. Metab. 282, E1334-E1341
-
(2002)
Am. J. Physiol. Endocrinol. Metab.
, vol.282
, pp. E1334-E1341
-
-
Li, J.1
Yu, X.2
Pan, W.3
Unger, R.H.4
-
60
-
-
34047197114
-
Regulation of adiponectin and its receptors in response to development of diet-induced obesity in mice
-
Bullen, Jr., J. W., Bluher, S., Kelesidis, T., and Mantzoros, C. S. (2007) Regulation of adiponectin and its receptors in response to development of diet-induced obesity in mice. Am. J. Physiol. Endocrinol. Metab. 292, E1079-E1086
-
(2007)
Am. J. Physiol. Endocrinol. Metab.
, vol.292
, pp. E1079-E1086
-
-
Bullen, J.W.1
Bluher, S.2
Kelesidis, T.3
Mantzoros, C.S.4
-
61
-
-
0036263641
-
Differential effects of tumor necrosis factoralpha on protein kinase C isoforms alpha and delta mediate inhibition of insulin receptor signaling
-
Rosenzweig, T., Braiman, L., Bak, A., Alt, A., Kuroki, T., and Sampson, S. R. (2002) Differential effects of tumor necrosis factoralpha on protein kinase C isoforms alpha and delta mediate inhibition of insulin receptor signaling. Diabetes 51, 1921-1930
-
(2002)
Diabetes
, vol.51
, pp. 1921-1930
-
-
Rosenzweig, T.1
Braiman, L.2
Bak, A.3
Alt, A.4
Kuroki, T.5
Sampson, S.R.6
-
62
-
-
0033974348
-
The adipoinsular axis: Effects of leptin on pancreatic beta-cells
-
Kieffer, T. J., and Habener, J. F. (2000) The adipoinsular axis: effects of leptin on pancreatic beta-cells. Am. J. Physiol. Endocrinol. Metab. 278, E1-E14
-
(2000)
Am. J. Physiol. Endocrinol. Metab.
, vol.278
, pp. E1-E14
-
-
Kieffer, T.J.1
Habener, J.F.2
-
63
-
-
33645863768
-
Transcriptional regulation of metabolism
-
Desvergne, B., Michalik, L., and Wahli, W. (2006) Transcriptional regulation of metabolism. Physiol. Rev. 86, 465-514
-
(2006)
Physiol. Rev.
, vol.86
, pp. 465-514
-
-
Desvergne, B.1
Michalik, L.2
Wahli, W.3
-
64
-
-
0036317748
-
Increased fatty acid re-esterification by PEPCK overexpression in adipose tissue leads to obesity without insulin resistance
-
Franckhauser, S., Muñoz, S., Pujol, A., Casellas, A., Riu, E., Otaegui, P., Su, B., and Bosch, F. (2002) Increased fatty acid re-esterification by PEPCK overexpression in adipose tissue leads to obesity without insulin resistance. Diabetes 51, 624-630
-
(2002)
Diabetes
, vol.51
, pp. 624-630
-
-
Franckhauser, S.1
Muñoz, S.2
Pujol, A.3
Casellas, A.4
Riu, E.5
Otaegui, P.6
Su, B.7
Bosch, F.8
-
65
-
-
0037423268
-
Opposite effects of background genotype on muscle and liver insulin sensitivity of lipoatrophic mice. Role of triglyceride clearance
-
Colombo, C., Haluzik, M., Cutson, J. J., Dietz, K. R., Marcus-Samuels, B., Vinson, C., Gavrilova, O., and Reitman, M. L. (2003) Opposite effects of background genotype on muscle and liver insulin sensitivity of lipoatrophic mice. Role of triglyceride clearance. J. Biol. Chem. 278, 3992-3999
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 3992-3999
-
-
Colombo, C.1
Haluzik, M.2
Cutson, J.J.3
Dietz, K.R.4
Marcus-Samuels, B.5
Vinson, C.6
Gavrilova, O.7
Reitman, M.L.8
-
66
-
-
37349006913
-
TNF-alpha and adipocyte biology
-
Cawthorn, W. P., and Sethi, J. K. (2008) TNF-alpha and adipocyte biology. FEBS Lett. 582, 117-131
-
(2008)
FEBS Lett.
, vol.582
, pp. 117-131
-
-
Cawthorn, W.P.1
Sethi, J.K.2
-
67
-
-
28444483953
-
Insulin regulation of PEPCK gene expression: A model for rapid and reversible modulation
-
Quinn, P. G., and Yeagley, D. (2005) Insulin regulation of PEPCK gene expression: a model for rapid and reversible modulation. Curr. Drug Targets Immune Endocr. Metabol. Disord. 5, 423-437
-
(2005)
Curr. Drug Targets Immune Endocr. Metabol. Disord.
, vol.5
, pp. 423-437
-
-
Quinn, P.G.1
Yeagley, D.2
-
68
-
-
50649097541
-
Fat and beyond: The diverse biology of PPARgamma
-
Tontonoz, P., and Spiegelman, B. M. (2008) Fat and beyond: the diverse biology of PPARgamma. Annu. Rev. Biochem. 77, 289-312
-
(2008)
Annu. Rev. Biochem.
, vol.77
, pp. 289-312
-
-
Tontonoz, P.1
Spiegelman, B.M.2
-
69
-
-
76049086229
-
PPARgamma activation in adipocytes is sufficient for systemic insulin sensitization
-
Sugii, S., Olson, P., Sears, D. D., Saberi, M., Atkins, A. R., Barish, G.D., Hong, S.H., Castro, G.L., Yin, Y. Q., Nelson, M. C., Hsiao, G., Greaves, D.R., Downes, M., Yu, R.T., Olefsky, J.M., and Evans, R.M. (2009) PPARgamma activation in adipocytes is sufficient for systemic insulin sensitization. Proc. Natl. Acad. Sci. USA 106, 22504-22509
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 22504-22509
-
-
Sugii, S.1
Olson, P.2
Sears, D.D.3
Saberi, M.4
Atkins, A.R.5
Barish, G.D.6
Hong, S.H.7
Castro, G.L.8
Yin, Y.Q.9
Nelson, M.C.10
Hsiao, G.11
Greaves, D.R.12
Downes, M.13
Yu, R.T.14
Olefsky, J.M.15
Evans, R.M.16
-
70
-
-
42449147456
-
Homocysteine upregulates resistin production from adipocytes in vivo and in vitro
-
Li, Y., Jiang, C., Xu, G., Wang, N., Zhu, Y., Tang, C., and Wang, X. (2008) Homocysteine upregulates resistin production from adipocytes in vivo and in vitro. Diabetes 57, 817-827
-
(2008)
Diabetes
, vol.57
, pp. 817-827
-
-
Li, Y.1
Jiang, C.2
Xu, G.3
Wang, N.4
Zhu, Y.5
Tang, C.6
Wang, X.7
-
71
-
-
0037205499
-
Mechanisms regulating adipocyte expression of resistin
-
Hartman, H. B., Hu, X., Tyler, K.X., Dalal, C. K., and Lazar, M. A. (2002) Mechanisms regulating adipocyte expression of resistin. J. Biol. Chem. 277, 19754-19761
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 19754-19761
-
-
Hartman, H.B.1
Hu, X.2
Tyler, K.X.3
Dalal, C.K.4
Lazar, M.A.5
-
72
-
-
0037452139
-
Adiponectin and protection against type 2 diabetes mellitus
-
Spranger, J., Kroke, A., Möhlig, M., Bergmann, M. M., Ristow, M., Boeing, H., and Pfeiffer, A. F. (2003) Adiponectin and protection against type 2 diabetes mellitus. Lancet 361, 226-228
-
(2003)
Lancet
, vol.361
, pp. 226-228
-
-
Spranger, J.1
Kroke, A.2
Möhlig, M.3
Bergmann, M.M.4
Ristow, M.5
Boeing, H.6
Pfeiffer, A.F.7
-
73
-
-
17644387796
-
Factor analysis of clustered cardiovascular risks in adolescence: Obesity is the predominant correlate of risk among youth
-
Goodman, E., Dolan, L. M., Morrison, J. A., and Daniels, S. R. (2005) Factor analysis of clustered cardiovascular risks in adolescence: obesity is the predominant correlate of risk among youth. Circulation 111, 1970-1977
-
(2005)
Circulation
, vol.111
, pp. 1970-1977
-
-
Goodman, E.1
Dolan, L.M.2
Morrison, J.A.3
Daniels, S.R.4
-
74
-
-
0035856980
-
Biochemistry and molecular cell biology of diabetic complications
-
Brownlee, M. (2001) Biochemistry and molecular cell biology of diabetic complications. Nature 414, 813-820
-
(2001)
Nature
, vol.414
, pp. 813-820
-
-
Brownlee, M.1
-
75
-
-
0034794309
-
Targeting of protein kinase C delta to mitochondria in the oxidative stress response
-
Majumder, P. K., Mishra, N. C., Sun, X., Bharti, A., Kharbanda, S., Saxena, S., and Kufe, D. (2001) Targeting of protein kinase C delta to mitochondria in the oxidative stress response. Cell Growth Differ. 12, 465-470
-
(2001)
Cell Growth Differ.
, vol.12
, pp. 465-470
-
-
Majumder, P.K.1
Mishra, N.C.2
Sun, X.3
Bharti, A.4
Kharbanda, S.5
Saxena, S.6
Kufe, D.7
-
76
-
-
12144273607
-
PKC-delta-dependent activation of oxidative stress in adipocytes of obese and insulin-resistant mice: Role for NADPH oxidase
-
Talior, I., Tennenbaum, T., Kuroki, T., and Eldar-Finkelman, H. (2005) PKC-delta-dependent activation of oxidative stress in adipocytes of obese and insulin-resistant mice: role for NADPH oxidase. Am. J. Physiol. Endocrinol. Metab. 288, E405-E411
-
(2005)
Am. J. Physiol. Endocrinol. Metab.
, vol.288
, pp. E405-E411
-
-
Talior, I.1
Tennenbaum, T.2
Kuroki, T.3
Eldar-Finkelman, H.4
-
77
-
-
0033233463
-
Protein kinase Cdeltamediates insulin-induced glucose transport inprimary cultures of rat skeletalmuscle
-
Braiman, L., Alt, A., Kuroki, T., Ohba, M., Bak, A., Tennenbaum, T., and Sampson, S. R. (1999) Protein kinase Cdeltamediates insulin-induced glucose transport inprimary cultures of rat skeletalmuscle. Mol. Endocrinol. 13, 2002-2012
-
(1999)
Mol. Endocrinol.
, vol.13
, pp. 2002-2012
-
-
Braiman, L.1
Alt, A.2
Kuroki, T.3
Ohba, M.4
Bak, A.5
Tennenbaum, T.6
Sampson, S.R.7
-
78
-
-
77449139439
-
Overexpression of kinasenegative protein kinase Cdelta in pancreatic beta-cells protects mice from diet-induced glucose intolerance and beta-cell dysfunction
-
Hennige, A.M., Ranta, F., Heinzelmann, I., Düfer, M., Michael, D., Braumüller, H., Lutz, S. Z., Lammers, R., Drews, G., Bosch, F., Häring, H. U., and Ullrich, S. (2010) Overexpression of kinasenegative protein kinase Cdelta in pancreatic beta-cells protects mice from diet-induced glucose intolerance and beta-cell dysfunction. Diabetes 59, 119-127
-
(2010)
Diabetes
, vol.59
, pp. 119-127
-
-
Hennige, A.M.1
Ranta, F.2
Heinzelmann, I.3
Düfer, M.4
Michael, D.5
Braumüller, H.6
Lutz, S.Z.7
Lammers, R.8
Drews, G.9
Bosch, F.10
Häring, H.U.11
Ullrich, S.12
-
79
-
-
9644260361
-
Genetic determinants of energy expenditure and insulin resistance in diet-induced obesity inmice
-
Almind, K., and Kahn, C.R. (2004) Genetic determinants of energy expenditure and insulin resistance in diet-induced obesity inmice. Diabetes 53, 3274-3285
-
(2004)
Diabetes
, vol.53
, pp. 3274-3285
-
-
Almind, K.1
Kahn, C.R.2
-
80
-
-
57749091893
-
P66Shcgenerated oxidative signal promotes fat accumulation
-
Berniakovich, I., Trinei, M., Stendardo, M., Migliaccio, E., Minucci, S., Bernardi, P., Pelicci, P. G., and Giorgio, M. (2008) p66Shcgenerated oxidative signal promotes fat accumulation. J. Biol. Chem. 283, 34283-34293
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 34283-34293
-
-
Berniakovich, I.1
Trinei, M.2
Stendardo, M.3
Migliaccio, E.4
Minucci, S.5
Bernardi, P.6
Pelicci, P.G.7
Giorgio, M.8
-
81
-
-
77955798757
-
Mammalian life-span determinant p66shcA mediates obesity-induced insulin resistance
-
Ranieri, S. C., Fusco, S., Panieri, E., Labate, V., Mele, M., Tesori, V., Ferrara, A. M., Maulucci, G., De Spirito, M., Martorana, G. E., Galeotti, T., and Pani, G. (2010) Mammalian life-span determinant p66shcA mediates obesity-induced insulin resistance. Proc. Natl. Acad. Sci. USA 107, 13420-13425
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 13420-13425
-
-
Ranieri, S.C.1
Fusco, S.2
Panieri, E.3
Labate, V.4
Mele, M.5
Tesori, V.6
Ferrara, A.M.7
Maulucci, G.8
De Spirito, M.9
Martorana, G.E.10
Galeotti, T.11
Pani, G.12
-
82
-
-
22744447211
-
Electron transfer between cytochrome c and p66Shc generates reactive oxygen species that trigger mitochondrial apoptosis
-
Giorgio, M., Migliaccio, E., Orsini, F., Paolucci, D., Moroni, M., Contursi, C., Pelliccia, G., Luzi, L., Minucci, S., Marcaccio, M., Pinton, P., Rizzuto, R., Bernardi, P., Paolucci, F., and Pelicci, P. G. (2005) Electron transfer between cytochrome c and p66Shc generates reactive oxygen species that trigger mitochondrial apoptosis. Cell 122, 221-233
-
(2005)
Cell
, vol.122
, pp. 221-233
-
-
Giorgio, M.1
Migliaccio, E.2
Orsini, F.3
Paolucci, D.4
Moroni, M.5
Contursi, C.6
Pelliccia, G.7
Luzi, L.8
Minucci, S.9
Marcaccio, M.10
Pinton, P.11
Rizzuto, R.12
Bernardi, P.13
Paolucci, F.14
Pelicci, P.G.15
-
83
-
-
17044450243
-
Loss of PKC-delta alters cardiac metabolism
-
Mayr, M., Chung, Y. L., Mayr, U., McGregor, E., Troy, H., Baier, G., Leitges, M., Dunn, M. J., Griffiths, J. R., and Xu, Q. (2004) Loss of PKC-delta alters cardiac metabolism. Am. J. Physiol. Heart Circ. Physiol. 287, H937-H945
-
(2004)
Am. J. Physiol. Heart Circ. Physiol.
, vol.287
, pp. H937-H945
-
-
Mayr, M.1
Chung, Y.L.2
Mayr, U.3
McGregor, E.4
Troy, H.5
Baier, G.6
Leitges, M.7
Dunn, M.J.8
Griffiths, J.R.9
Xu, Q.10
-
84
-
-
14044254273
-
Diabetes induces p66shc gene expression in human peripheral blood mononuclear cells: Relationship to oxidative stress
-
Pagnin, E., Fadini, G., deToni, R., Tiengo, A., Calò, L., and Avogaro, A. (2005) Diabetes induces p66shc gene expression in human peripheral blood mononuclear cells: relationship to oxidative stress. J. Clin. Endocrinol. Metab. 90, 1130-1136
-
(2005)
J. Clin. Endocrinol. Metab.
, vol.90
, pp. 1130-1136
-
-
Pagnin, E.1
Fadini, G.2
DeToni, R.3
Tiengo, A.4
Calò, L.5
Avogaro, A.6
-
85
-
-
84891465462
-
The endothelium abridges insulin resistance to premature aging
-
Avogaro, A., de Kreutzenberg, S. V., Federici, M., and Fadini, G. P. (2013) The endothelium abridges insulin resistance to premature aging. J. Am. Heart Assoc. 2, e000262
-
(2013)
J. Am. Heart Assoc.
, vol.2
, pp. e000262
-
-
Avogaro, A.1
De Kreutzenberg, S.V.2
Federici, M.3
Fadini, G.P.4
-
86
-
-
84857687489
-
Linking mitochondrial bioenergetics to insulin resistance via redox biology
-
Fisher-Wellman, K. H., and Neufer, P. D. (2012) Linking mitochondrial bioenergetics to insulin resistance via redox biology. Trends Endocrinol. Metab. 23, 142-153
-
(2012)
Trends Endocrinol. Metab.
, vol.23
, pp. 142-153
-
-
Fisher-Wellman, K.H.1
Neufer, P.D.2
-
87
-
-
84885012414
-
Mitochondrial glutathione depletion reveals a novel role for the pyruvate dehydrogenase complex as a key H2O2-emitting source under conditions of nutrient overload
-
Fisher-Wellman, K. H., Gilliam, L. A., Lin, C. T., Cathey, B. L., Lark, D. S., and Neufer, P. D. (2013) Mitochondrial glutathione depletion reveals a novel role for the pyruvate dehydrogenase complex as a key H2O2-emitting source under conditions of nutrient overload. Free Radic. Biol. Med. 65, 1201-1208
-
(2013)
Free Radic. Biol. Med.
, vol.65
, pp. 1201-1208
-
-
Fisher-Wellman, K.H.1
Gilliam, L.A.2
Lin, C.T.3
Cathey, B.L.4
Lark, D.S.5
Neufer, P.D.6
-
88
-
-
84919469789
-
Genetic activation of pyruvate dehydrogenase alters oxidative substrate selection to induce skeletal muscle insulin resistance
-
Rahimi, Y., Camporez, J. P., Petersen, M. C., Pesta, D., Perry, R. J., Jurczak, M. J., Cline, G. W., and Shulman, G. I. (2014) Genetic activation of pyruvate dehydrogenase alters oxidative substrate selection to induce skeletal muscle insulin resistance. Proc. Natl. Acad. Sci. USA 111, 16508-16513
-
(2014)
Proc. Natl. Acad. Sci. USA
, vol.111
, pp. 16508-16513
-
-
Rahimi, Y.1
Camporez, J.P.2
Petersen, M.C.3
Pesta, D.4
Perry, R.J.5
Jurczak, M.J.6
Cline, G.W.7
Shulman, G.I.8
-
89
-
-
84875412120
-
Mitochondrial deficiency is associated with insulin resistance
-
Goodpaster, B. H. (2013) Mitochondrial deficiency is associated with insulin resistance. Diabetes 62, 1032-1035
-
(2013)
Diabetes
, vol.62
, pp. 1032-1035
-
-
Goodpaster, B.H.1
-
90
-
-
84876452139
-
Retinoids: Potent regulators of metabolism
-
Brun, P. J., Yang, K. J., Lee, S. A., Yuen, J. J., and Blaner, W. S. (2013) Retinoids: potent regulators of metabolism. Biofactors 39, 151-163
-
(2013)
Biofactors
, vol.39
, pp. 151-163
-
-
Brun, P.J.1
Yang, K.J.2
Lee, S.A.3
Yuen, J.J.4
Blaner, W.S.5
-
91
-
-
84930958553
-
Vitamin A and retinoids asmitochondrial toxicants
-
DeOliveira, M. R. (2015) Vitamin A and retinoids asmitochondrial toxicants. Oxid. Med. Cell. Longev. 2015, 140267
-
(2015)
Oxid. Med. Cell. Longev.
, vol.2015
, pp. 140267
-
-
DeOliveira, M.R.1
-
92
-
-
0003298802
-
Infectiousmorbidity
-
Oxford University Press, New York
-
Sommer, A., and West, K. P. (1996) Infectiousmorbidity. In Vitamin AD eficiency:Health, Survival and Vision, pp. 62-83, Oxford University Press, New York
-
(1996)
Vitamin AD Eficiency: Health, Survival and Vision
, pp. 62-83
-
-
Sommer, A.1
West, K.P.2
-
93
-
-
0036712422
-
Extent of Vitamin A deficiency among preschool children and women of reproductive age
-
West, Jr., K. P. (2002) Extent of vitamin A deficiency among preschool children and women of reproductive age. J. Nutr. 132 (9, Suppl), 2857S-2866S
-
(2002)
J. Nutr.
, vol.132
, Issue.9
, pp. 2857S-2866S
-
-
West, K.P.1
-
94
-
-
33644856918
-
The acute and chronic toxic effects of Vitamin A
-
Penniston, K. L., and Tanumihardjo, S. A. (2006) The acute and chronic toxic effects of vitamin A. Am. J. Clin. Nutr. 83, 191-201
-
(2006)
Am. J. Clin. Nutr.
, vol.83
, pp. 191-201
-
-
Penniston, K.L.1
Tanumihardjo, S.A.2
-
95
-
-
84902665688
-
Effects of diet and strainonmouse serumandtissue retinoid concentrations
-
Obrochta, K.M., Kane, M.A., and Napoli, J. L. (2014) Effects of diet and strainonmouse serumandtissue retinoid concentrations. PLoS One 9, e99435
-
(2014)
PLoS One
, vol.9
, pp. e99435
-
-
Obrochta, K.M.1
Kane, M.A.2
Napoli, J.L.3
-
96
-
-
0025917013
-
Interactions of retinol with binding proteins: Studies with rat cellular retinol-binding protein and with rat retinol-binding protein
-
Noy, N., and Blaner, W. S. (1991) Interactions of retinol with binding proteins: studies with rat cellular retinol-binding protein and with rat retinol-binding protein. Biochemistry 30, 6380-6386
-
(1991)
Biochemistry
, vol.30
, pp. 6380-6386
-
-
Noy, N.1
Blaner, W.S.2
-
97
-
-
0034660094
-
Retinoid-binding proteins: Mediators of retinoid action
-
Noy, N. (2000) Retinoid-binding proteins: mediators of retinoid action. Biochem. J. 348, 481-495
-
(2000)
Biochem. J.
, vol.348
, pp. 481-495
-
-
Noy, N.1
-
98
-
-
0035847091
-
Characterization of a new member of the fatty acid-binding protein family that binds all-trans-retinol
-
Vogel, S., Mendelsohn, C. L., Mertz, J. R., Piantedosi, R., Waldburger, C., Gottesman, M. E., and Blaner, W. S. (2001) Characterization of a new member of the fatty acid-binding protein family that binds all-trans-retinol. J. Biol. Chem. 276, 1353-1360
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 1353-1360
-
-
Vogel, S.1
Mendelsohn, C.L.2
Mertz, J.R.3
Piantedosi, R.4
Waldburger, C.5
Gottesman, M.E.6
Blaner, W.S.7
-
99
-
-
0035233948
-
Retinoids as ligands and coactivators of protein kinase C alpha
-
Imam, A., Hoyos, B., Swenson, C., Levi, E., Chua, R., Viriya, E., and Hammerling, U. (2001) Retinoids as ligands and coactivators of protein kinase C alpha. FASEB J. 15, 28-30
-
(2001)
FASEB J.
, vol.15
, pp. 28-30
-
-
Imam, A.1
Hoyos, B.2
Swenson, C.3
Levi, E.4
Chua, R.5
Viriya, E.6
Hammerling, U.7
-
100
-
-
0034194467
-
Why cytoplasmic signalling proteins should be recruited to cell membranes
-
Kholodenko, B. N., Hoek, J. B., and Westerhoff, H. V. (2000) Why cytoplasmic signalling proteins should be recruited to cell membranes. Trends Cell Biol. 10, 173-178
-
(2000)
Trends Cell Biol.
, vol.10
, pp. 173-178
-
-
Kholodenko, B.N.1
Hoek, J.B.2
Westerhoff, H.V.3
-
101
-
-
0026496318
-
Effects of insulin and phorbol esters on subcellular distribution of protein kinase C isoforms in rat adipocytes
-
Farese, R.V., Standaert, M.L., Francois, A. J., Ways, K., Arnold, T. P., Hernandez, H., and Cooper, D. R. (1992) Effects of insulin and phorbol esters on subcellular distribution of protein kinase C isoforms in rat adipocytes. Biochem. J. 288, 319-323
-
(1992)
Biochem. J.
, vol.288
, pp. 319-323
-
-
Farese, R.V.1
Standaert, M.L.2
Francois, A.J.3
Ways, K.4
Arnold, T.P.5
Hernandez, H.6
Cooper, D.R.7
-
102
-
-
38049098727
-
Effect of RBP4 gene variants on circulating RBP4 concentration and type 2 diabetes in a Chinese population
-
Hu, C., Jia, W., Zhang, R., Wang, C., Lu, J., Wu, H., Fang, Q., Ma, X., and Xiang, K. (2008) Effect of RBP4 gene variants on circulating RBP4 concentration and type 2 diabetes in a Chinese population. Diabet. Med. 25, 11-18
-
(2008)
Diabet. Med.
, vol.25
, pp. 11-18
-
-
Hu, C.1
Jia, W.2
Zhang, R.3
Wang, C.4
Lu, J.5
Wu, H.6
Fang, Q.7
Ma, X.8
Xiang, K.9
-
103
-
-
33846380268
-
Identification of a regulatory SNP intheretinol bindingprotein4 gene associated with type 2 diabetes in Mongolia
-
Munkhtulga, L., Nakayama, K., Utsumi, N., Yanagisawa, Y., Gotoh, T., Omi, T., Kumada, M., Erdenebulgan, B., Zolzaya, K., Lkhagvasuren, T., and Iwamoto, S. (2007) Identification of a regulatory SNP intheretinol bindingprotein4 gene associated with type 2 diabetes in Mongolia. Hum. Genet. 120, 879-888
-
(2007)
Hum. Genet.
, vol.120
, pp. 879-888
-
-
Munkhtulga, L.1
Nakayama, K.2
Utsumi, N.3
Yanagisawa, Y.4
Gotoh, T.5
Omi, T.6
Kumada, M.7
Erdenebulgan, B.8
Zolzaya, K.9
Lkhagvasuren, T.10
Iwamoto, S.11
-
104
-
-
56449104497
-
Effect of fenretinide and low-dose tamoxifen on insulin sensitivity in premenopausal women at high risk for breast cancer
-
Johansson, H., Gandini, S., Guerrieri-Gonzaga, A., Iodice, S., Ruscica, M., Bonanni, B., Gulisano, M., Magni, P., Formelli, F., and Decensi, A. (2008) Effect of fenretinide and low-dose tamoxifen on insulin sensitivity in premenopausal women at high risk for breast cancer. Cancer Res. 68, 9512-9518
-
(2008)
Cancer Res.
, vol.68
, pp. 9512-9518
-
-
Johansson, H.1
Gandini, S.2
Guerrieri-Gonzaga, A.3
Iodice, S.4
Ruscica, M.5
Bonanni, B.6
Gulisano, M.7
Magni, P.8
Formelli, F.9
Decensi, A.10
-
105
-
-
84964694383
-
Transthyretin antisense oligonucleotides lower circulating RBP4 levels and improve insulin sensitivity in obese mice
-
Zemany, L., Bhanot, S., Peroni, O. D., Murray, S. F., Moraes-Vieira, P.M., Castoldi, A., Manchem, P., Guo, S., Monia, B. P., and Kahn, B. B. (2015) Transthyretin antisense oligonucleotides lower circulating RBP4 levels and improve insulin sensitivity in obese mice. Diabetes 64, 1603-1614
-
(2015)
Diabetes
, vol.64
, pp. 1603-1614
-
-
Zemany, L.1
Bhanot, S.2
Peroni, O.D.3
Murray, S.F.4
Moraes-Vieira, P.M.5
Castoldi, A.6
Manchem, P.7
Guo, S.8
Monia, B.P.9
Kahn, B.B.10
-
106
-
-
30044446067
-
RBP4, an unexpected adipokine
-
discussion 31
-
Tamori, Y., Sakaue, H., and Kasuga, M. (2006) RBP4, an unexpected adipokine. Nat. Med. 12, 30-31, discussion 31
-
(2006)
Nat. Med.
, vol.12
, pp. 30-31
-
-
Tamori, Y.1
Sakaue, H.2
Kasuga, M.3
-
107
-
-
83255185195
-
Signaling by Vitamin A and retinolbinding protein in regulation of insulin responses and lipid homeostasis
-
Berry, D. C., and Noy, N. (2012) Signaling by vitamin A and retinolbinding protein in regulation of insulin responses and lipid homeostasis. Biochim. Biophys. Acta 1821, 168-176
-
(2012)
Biochim. Biophys. Acta
, vol.1821
, pp. 168-176
-
-
Berry, D.C.1
Noy, N.2
-
108
-
-
84864754109
-
Two protein kinase C isoforms, δ and e, regulate energy homeostasis in mitochondria by transmitting opposing signals to the pyruvate dehydrogenase complex
-
Gong, J., Hoyos, B., Acin-Perez, R., Vinogradov, V., Shabrova, E., Zhao, F., Leitges, M., Fischman, D., Manfredi, G., and Hammerling, U. (2012) Two protein kinase C isoforms, δ and e, regulate energy homeostasis in mitochondria by transmitting opposing signals to the pyruvate dehydrogenase complex. FASEB J. 26, 3537-3549
-
(2012)
FASEB J.
, vol.26
, pp. 3537-3549
-
-
Gong, J.1
Hoyos, B.2
Acin-Perez, R.3
Vinogradov, V.4
Shabrova, E.5
Zhao, F.6
Leitges, M.7
Fischman, D.8
Manfredi, G.9
Hammerling, U.10
|