Exacerbated vein graft arteriosclerosis in protein kinase Cδ-null mice

Journal of Clinical Investigation

Volumn 108, Issue 10, 2001, Pages 1505-1512

  Leitges, Michael ^a   Mayr, Manuel ^b   Braun, Ursula ^a   Mayr, Ursula ^c   Li, Chaohong ^b   Pfister, Gerald ^b   Ghaffari Tabrizi, Nassim ^c   Baier, Gottfried ^c   Hu, Yanhua ^c   Xu, Qingbo ^b,d  

^a MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

^b ERICH SCHMID INSTITUTE OF MATERIALS SCIENCE   (Austria)

^c INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^d ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CYTOCHROME C; PROTEIN KINASE C;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTERIOSCLEROSIS; ARTICLE; ATHEROSCLEROSIS; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME DENATURATION; ENZYME RELEASE; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SMOOTH MUSCLE FIBER; VEIN GRAFT;

ANIMALS; ARTERIOSCLEROSIS; BLOOD VESSEL PROSTHESIS; ISOENZYMES; MICE; MICE, KNOCKOUT; PROTEIN KINASE C; PROTEIN KINASE C-DELTA; PROTEIN TRANSPORT; VEINS;

EID: 0035179086     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI200112902     Document Type: Article

References (41)

1. The molecular heterogeneity of protein kinase C and its implications for cellular regulation
2. New insights into the regulation of protein kinase C and novel phorbol ester receptors
3. Protein kinase C isozymes and the regulation of diverse cell responses
4. Protein kinase C delta inhibits the proliferation of vascular smooth muscle cells by suppressing G1 cyclin expression
5. Protein kinase C-delta is an important signaling molecule in insulin-like growth factor I receptor-mediated cell transformation
6. Requirement for protein kinase C in reactive oxygen species-induced apoptosis of vascular smooth muscle cells
7. Mitochondrial translocation of protein kinase C delta in phorbol ester-induced cytochrome c release and apoptosis
8. PKC-theta is required for TCR-induced NF-kappaB activation in mature but not immature T lymphocytes
9. Aortocoronary saphenous vein graft disease: Pathogenesis, predisposition, and prevention
10. The pathogenesis of atherosclerosis: A perspective for the 1990s
11. Biomechanical-stress-induced signaling and gene expression in the development of arteriosclerosis
12. Cell surface trafficking of Fas: A rapid mechanism of p53-mediated apoptosis
13. Smooth muscle cell apoptosis in arteriosclerosis
14. Proteolytic activation of protein kinase C delta by an ICE/CED 3-like protease induces characteristics of apoptosis
15. Targeted correction of a mutant HPRT gene in mouse embryonic stem cells
16. Mouse model of venous bypass graft arteriosclerosis
17. Rapid development of vein graft atheroma in ApoE-deficient mice
18. Reduced neointima hyperplasia of vein bypass grafts in intercellular adhesion molecule-1-deficient mice
19. Biomechanical stress-induced apoptosis in vein grafts involves p38 mitogen-activated protein kinases
20. Inhibition of neointima hyperplasia of mouse vein grafts by locally applied suramin
21. Cyclic strain stress-induced mitogen-activated protein kinase (MAPK) phosphatase 1 expression in vascular smooth muscle cells is regulated by Ras/Rac-MAPK pathways
22. Mitochondrial proliferation and paradoxical membrane depolarization during terminal differentiation and apoptosis in a human colon carcinoma cell line
23. Superoxide production in vascular smooth muscle contributes to oxidative stress and impaired relaxation in atherosclerosis
24. Anoxia/reoxygenation-induced tolerance with respect to polymorphonuclear leukocyte adhesion to cultured endothelial cells. A nuclear factor-kappaB-mediated phenomenon
25. The mammalian UV response. c-Jun induction is required for exit from p53-imposed growth arrest
26. Direct evidence that initial oxidative stress triggered by preconditioning contributes to second window of protection by endogenous antioxidant enzyme in myocytes
27. Differential localization of protein kinase C delta by phorbol esters and related compounds using a fusion protein with green fluorescent protein
28. Phosphorylation of the respiratory burst oxidase subunit p47 as determined by two-dimensional phosphopeptide mapping
29. Evidence for apoptosis in advanced human atheroma. Colocalization with interleukin-1 beta-converting enzyme
30. Apoptosis of human vascular smooth muscle cells derived from normal vessels and coronary atherosclerotic plaques
31. Apoptosis in human atherosclerosis and restenosis
32. Evidence for apoptosis in human atherogenesis and in a rat vascular injury model
33. Defect in insulin-like growth factor-1 survival mechanism in atherosclerotic plaque-derived vascular smooth muscle cells is mediated by reduced surface binding and signaling
34. Apoptosis of smooth muscle cells is not silent: Fas/FADD initiates a program of inflammatory gene expression
35. Current perspective on the role of apoptosis in atherothrombotic disease
36. Wild-type p53 gene transfer inhibits neointima formation in human saphenous vein by modulation of smooth muscle cell migration and induction of apoptosis
37. Genetic locus in mice that blocks development of atherosclerosis despite extreme hyperlipidemia
38. Protein kinase Cdelta targets mitochondria, alters mitochondrial membrane potential, and induces apoptosis in normal and neoplastic keratinocytes when overexpressed by an adenoviral vector
39. Proteolytic activation of protein kinase C delta by an ICE-like protease in apoptotic cells
40. Protein kinase C delta is essential for etoposide-induced apoptosis in salivary gland acinar cells
41. Ras/rac-dependent activation of p38 mitogen-activated protein kinases in smooth muscle cells stimulated by cyclic strain stress