메뉴 건너뛰기




Volumn 62, Issue 4, 2013, Pages 1032-1035

Mitochondrial deficiency is associated with insulin resistance

Author keywords

[No Author keywords available]

Indexed keywords

6 PHOSPHOFRUCTOKINASE; ACETYL COENZYME A; LIPOPROTEIN LIPASE; PYRUVATE DEHYDROGENASE; REACTIVE OXYGEN METABOLITE; THIOREDOXIN;

EID: 84875412120     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db12-1612     Document Type: Article
Times cited : (105)

References (41)
  • 1
    • 0036788293 scopus 로고    scopus 로고
    • Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes
    • Kelley DE, He J, Menshikova EV, Ritov VB. Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes. Diabetes 2002;51:2944-2950
    • (2002) Diabetes , vol.51 , pp. 2944-2950
    • Kelley, D.E.1    He, J.2    Menshikova, E.V.3    Ritov, V.B.4
  • 2
    • 3042821172 scopus 로고    scopus 로고
    • Muscle fat oxidative capacity is not impaired by age but by physical inactivity: Association with insulin sensitivity
    • Rimbert V, Boirie Y, Bedu M, Hocquette J-F, Ritz P, Morio B. Muscle fat oxidative capacity is not impaired by age but by physical inactivity: association with insulin sensitivity. FASEB J 2004;18:737-739
    • (2004) FASEB J , vol.18 , pp. 737-739
    • Rimbert, V.1    Boirie, Y.2    Bedu, M.3    Hocquette, J.-F.4    Ritz, P.5    Morio, B.6
  • 4
    • 42649127400 scopus 로고    scopus 로고
    • IRS1-independent defects define major nodes of insulin resistance
    • Hoehn KL, Hohnen-Behrens C, Cederberg A, et al. IRS1-independent defects define major nodes of insulin resistance. Cell Metab 2008;7:421-433
    • (2008) Cell Metab , vol.7 , pp. 421-433
    • Hoehn, K.L.1    Hohnen-Behrens, C.2    Cederberg, A.3
  • 5
    • 58149379936 scopus 로고    scopus 로고
    • Skeletal Muscle "mitochondrial deficiency" does not mediate insulin resistance
    • Holloszy JO. Skeletal muscle "mitochondrial deficiency" does not mediate insulin resistance. Am J Clin Nutr 2009;89:463S-466S
    • (2009) Am J Clin Nutr , vol.89
    • Holloszy, J.O.1
  • 6
    • 84860430699 scopus 로고    scopus 로고
    • Lipid-induced mitochondrial stress and insulin action in muscle
    • Muoio DM, Neufer PD. Lipid-induced mitochondrial stress and insulin action in muscle. Cell Metab 2012;15:595-605
    • (2012) Cell Metab , vol.15 , pp. 595-605
    • Muoio, D.M.1    Neufer, P.D.2
  • 7
    • 50549202600 scopus 로고
    • The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus
    • Randle PJ, Garland PB, Hales CN, Newsholme EA. The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus. Lancet 1963;1:785-789
    • (1963) Lancet , vol.1 , pp. 785-789
    • Randle, P.J.1    Garland, P.B.2    Hales, C.N.3    Newsholme, E.A.4
  • 8
    • 0017776141 scopus 로고
    • Inhibition of glucose uptake and glycogenolysis by availability of oleate in well-oxygenated perfused skeletal muscle
    • Rennie MJ, Holloszy JO. Inhibition of glucose uptake and glycogenolysis by availability of oleate in well-oxygenated perfused skeletal muscle. Biochem J 1977;168:161-170
    • (1977) Biochem J , vol.168 , pp. 161-170
    • Rennie, M.J.1    Holloszy, J.O.2
  • 9
    • 0025695163 scopus 로고
    • Hyperglycemia normalizes insulin-stimulated skeletal muscle glucose oxidation and storage in noninsulin-dependent diabetes mellitus
    • Kelley DE, Mandarino LJ. Hyperglycemia normalizes insulin-stimulated skeletal muscle glucose oxidation and storage in noninsulin-dependent diabetes mellitus. J Clin Invest 1990;86:1999-2007
    • (1990) J Clin Invest , vol.86 , pp. 1999-2007
    • Kelley, D.E.1    Mandarino, L.J.2
  • 10
    • 0027218865 scopus 로고
    • Interaction between glucose and free fatty acid metabolism in human skeletal muscle
    • Kelley DE, Mokan M, Simoneau JA, Mandarino LJ. Interaction between glucose and free fatty acid metabolism in human skeletal muscle. J Clin Invest 1993;92:91-98
    • (1993) J Clin Invest , vol.92 , pp. 91-98
    • Kelley, D.E.1    Mokan, M.2    Simoneau, J.A.3    Mandarino, L.J.4
  • 11
    • 0029980383 scopus 로고    scopus 로고
    • Interaction of carbohydrate and fat fuels in human skeletal muscle: Impact of obesity and NIDDM
    • Mandarino LJ, Consoli A, Jain A, Kelley DE. Interaction of carbohydrate and fat fuels in human skeletal muscle: impact of obesity and NIDDM. Am J Physiol 1996;270:E463-E470
    • (1996) Am J Physiol , vol.270
    • Mandarino, L.J.1    Consoli, A.2    Jain, A.3    Kelley, D.E.4
  • 12
    • 0029991872 scopus 로고    scopus 로고
    • Glucose and insulin-induced inhibition of fatty acid oxidation: The glucose-fatty acid cycle reversed
    • Sidossis LS, Wolfe RR. Glucose and insulin-induced inhibition of fatty acid oxidation: the glucose-fatty acid cycle reversed. Am J Physiol 1996;270: E733-E738
    • (1996) Am J Physiol , vol.270
    • Sidossis, L.S.1    Wolfe, R.R.2
  • 13
    • 0024998320 scopus 로고
    • Time course of exerciseinduced decline in malonyl-CoA in different muscle types
    • Winder WW, Arogyasami J, Elayan IM, Cartmill D. Time course of exerciseinduced decline in malonyl-CoA in different muscle types. Am J Physiol 1990;259:E266-E271
    • (1990) Am J Physiol , vol.259
    • Winder, W.W.1    Arogyasami, J.2    Elayan, I.M.3    Cartmill, D.4
  • 14
    • 0029067962 scopus 로고
    • The mitochondrial carnitine palmitoyltransferase system: Its broadening role in fuel homoeostasis and new insights into its molecular features
    • McGarry JD. The mitochondrial carnitine palmitoyltransferase system: its broadening role in fuel homoeostasis and new insights into its molecular features. Biochem Soc Trans 1995;23:321-324
    • (1995) Biochem Soc Trans , vol.23 , pp. 321-324
    • McGarry, J.D.1
  • 15
    • 84864293537 scopus 로고    scopus 로고
    • Role of intramyocelluar lipids in human health
    • Coen PM, Goodpaster BH. Role of intramyocelluar lipids in human health. Trends Endocrinol Metab 2012;23:391-398
    • (2012) Trends Endocrinol Metab , vol.23 , pp. 391-398
    • Coen, P.M.1    Goodpaster, B.H.2
  • 16
    • 0025249970 scopus 로고
    • Endurance training decreases plasma glucose turnover and oxidation during moderateintensity exercise in men
    • Coggan AR, Kohrt WM, Spina RJ, Bier DM, Holloszy JO. Endurance training decreases plasma glucose turnover and oxidation during moderateintensity exercise in men. J Appl Physiol 1990;68:990-996
    • (1990) J Appl Physiol , vol.68 , pp. 990-996
    • Coggan, A.R.1    Kohrt, W.M.2    Spina, R.J.3    Bier, D.M.4    Holloszy, J.O.5
  • 17
    • 0033400310 scopus 로고    scopus 로고
    • Skeletal muscle fatty acid metabolism in association with insulin resistance, obesity, and weight loss
    • Kelley DE, Goodpaster B, Wing RR, Simoneau JA. Skeletal muscle fatty acid metabolism in association with insulin resistance, obesity, and weight loss. Am J Physiol 1999;277:E1130-E1141
    • (1999) Am J Physiol , vol.277
    • Kelley, D.E.1    Goodpaster, B.2    Wing, R.R.3    Simoneau, J.A.4
  • 18
    • 78649508058 scopus 로고    scopus 로고
    • Total skeletal muscle PGC-1 deficiency uncouples mitochondrial derangements from fiber type determination and insulin sensitivity
    • Zechner C, Lai L, Zechner JF, et al. Total skeletal muscle PGC-1 deficiency uncouples mitochondrial derangements from fiber type determination and insulin sensitivity. Cell Metab 2010;12:633-642
    • (2010) Cell Metab , vol.12 , pp. 633-642
    • Zechner, C.1    Lai, L.2    Zechner, J.F.3
  • 19
    • 0042337449 scopus 로고    scopus 로고
    • Acetyl-CoA carboxylase 2 mutant mice are protected against obesity and diabetes induced by high-fat/high-carbohydrate diets
    • Abu-Elheiga L, Oh W, Kordari P, Wakil SJ. Acetyl-CoA carboxylase 2 mutant mice are protected against obesity and diabetes induced by high-fat/high- carbohydrate diets. Proc Natl Acad Sci USA 2003;100:10207-10212
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 10207-10212
    • Abu-Elheiga, L.1    Oh, W.2    Kordari, P.3    Wakil, S.J.4
  • 20
    • 72649089588 scopus 로고    scopus 로고
    • Acute or chronic upregulation of mitochondrial fatty acid oxidation has no net effect on whole-body energy expenditure or adiposity
    • Hoehn KL, Turner N, Swarbrick MM, et al. Acute or chronic upregulation of mitochondrial fatty acid oxidation has no net effect on whole-body energy expenditure or adiposity. Cell Metab 2010;11:70-76
    • (2010) Cell Metab , vol.11 , pp. 70-76
    • Hoehn, K.L.1    Turner, N.2    Swarbrick, M.M.3
  • 21
    • 3042551249 scopus 로고    scopus 로고
    • Increased beta-oxidation in muscle cells enhances insulin-stimulated glucose metabolism and protects against fatty acid-induced insulin resistance despite intramyocellular lipid accumulation
    • Perdomo G, Commerford SR, Richard AM, et al. Increased beta-oxidation in muscle cells enhances insulin-stimulated glucose metabolism and protects against fatty acid-induced insulin resistance despite intramyocellular lipid accumulation. J Biol Chem 2004;279:27177-27186
    • (2004) J Biol Chem , vol.279 , pp. 27177-27186
    • Perdomo, G.1    Commerford, S.R.2    Richard, A.M.3
  • 22
    • 34547588219 scopus 로고    scopus 로고
    • Excess lipid availability increases mitochondrial fatty acid oxidative capacity in muscle: Evidence against a role for reduced fatty acid oxidation in lipid-induced insulin resistance in rodents
    • Turner N, Bruce CR, Beale SM, et al. Excess lipid availability increases mitochondrial fatty acid oxidative capacity in muscle: evidence against a role for reduced fatty acid oxidation in lipid-induced insulin resistance in rodents. Diabetes 2007;56:2085-2092
    • (2007) Diabetes , vol.56 , pp. 2085-2092
    • Turner, N.1    Bruce, C.R.2    Beale, S.M.3
  • 23
    • 0029142737 scopus 로고
    • Muscle-specific overexpression of lipoprotein lipase causes a severe myopathy characterized by proliferation of mitochondria and peroxisomes in transgenic mice
    • Levak-Frank S, Radner H, Walsh A, et al. Muscle-specific overexpression of lipoprotein lipase causes a severe myopathy characterized by proliferation of mitochondria and peroxisomes in transgenic mice. J Clin Invest 1995;96:976-986
    • (1995) J Clin Invest , vol.96 , pp. 976-986
    • Levak-Frank, S.1    Radner, H.2    Walsh, A.3
  • 24
    • 21344444333 scopus 로고    scopus 로고
    • A high-fat diet coordinately downregulates genes required for mitochondrial oxidative phosphorylation in skeletal muscle
    • Sparks LM, Xie H, Koza RA, et al. A high-fat diet coordinately downregulates genes required for mitochondrial oxidative phosphorylation in skeletal muscle. Diabetes 2005;54:1926-1933
    • (2005) Diabetes , vol.54 , pp. 1926-1933
    • Sparks, L.M.1    Xie, H.2    Koza, R.A.3
  • 25
    • 0032752951 scopus 로고    scopus 로고
    • Markers of capacity to utilize fatty acids in human skeletal muscle: Relation to insulin resistance and obesity and effects of weight loss
    • Simoneau JA, Veerkamp JH, Turcotte LP, Kelley DE. Markers of capacity to utilize fatty acids in human skeletal muscle: relation to insulin resistance and obesity and effects of weight loss. FASEB J 1999;13:2051-2060
    • (1999) FASEB J , vol.13 , pp. 2051-2060
    • Simoneau, J.A.1    Veerkamp, J.H.2    Turcotte, L.P.3    Kelley, D.E.4
  • 26
    • 84859544293 scopus 로고    scopus 로고
    • Regulation of mitochondrial biogenesis by lipoprotein lipase in muscle of insulin-resistant offspring of parents with type 2 diabetes
    • Morino K, Petersen KF, Sono S, et al. Regulation of mitochondrial biogenesis by lipoprotein lipase in muscle of insulin-resistant offspring of parents with type 2 diabetes. Diabetes 2012;61:877-887
    • (2012) Diabetes , vol.61 , pp. 877-887
    • Morino, K.1    Petersen, K.F.2    Sono, S.3
  • 27
    • 43449097093 scopus 로고    scopus 로고
    • Asian Indians have enhanced skeletal muscle mitochondrial capacity to produce ATP in association with severe insulin resistance
    • Nair KS, Bigelow ML, Asmann YW, et al. Asian Indians have enhanced skeletal muscle mitochondrial capacity to produce ATP in association with severe insulin resistance. Diabetes 2008;57:1166-1175
    • (2008) Diabetes , vol.57 , pp. 1166-1175
    • Nair, K.S.1    Bigelow, M.L.2    Asmann, Y.W.3
  • 28
    • 79954632229 scopus 로고    scopus 로고
    • Effects of weight loss and exercise on insulin resistance, and intramyocellular triacylglycerol, diacylglycerol and ceramide
    • Dubé JJ, Amati F, Toledo FG, et al. Effects of weight loss and exercise on insulin resistance, and intramyocellular triacylglycerol, diacylglycerol and ceramide. Diabetologia 2011;54:1147-1156
    • (2011) Diabetologia , vol.54 , pp. 1147-1156
    • Dubé, J.J.1    Amati, F.2    Toledo, F.G.3
  • 29
    • 42449094965 scopus 로고    scopus 로고
    • Mitochondrial capacity in skeletal muscle is not stimulated by weight loss despite increases in insulin action and decreases in intramyocellular lipid content
    • Toledo FG, Menshikova EV, Azuma K, et al. Mitochondrial capacity in skeletal muscle is not stimulated by weight loss despite increases in insulin action and decreases in intramyocellular lipid content. Diabetes 2008;57: 987-994
    • (2008) Diabetes , vol.57 , pp. 987-994
    • Toledo, F.G.1    Menshikova, E.V.2    Azuma, K.3
  • 31
    • 37449020075 scopus 로고    scopus 로고
    • Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance
    • Koves TR, Ussher JR, Noland RC, et al. Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance. Cell Metab 2008;7:45-56
    • (2008) Cell Metab , vol.7 , pp. 45-56
    • Koves, T.R.1    Ussher, J.R.2    Noland, R.C.3
  • 32
    • 0033927667 scopus 로고    scopus 로고
    • Cellular mechanisms of insulin resistance
    • Shulman GI. Cellular mechanisms of insulin resistance. J Clin Invest 2000; 106:171-176
    • (2000) J Clin Invest , vol.106 , pp. 171-176
    • Shulman, G.I.1
  • 33
    • 17844391785 scopus 로고    scopus 로고
    • Interaction of physiological mechanisms in control of muscle glucose uptake
    • Wasserman DH, Ayala JE. Interaction of physiological mechanisms in control of muscle glucose uptake. Clin Exp Pharmacol Physiol 2005;32: 319-323
    • (2005) Clin Exp Pharmacol Physiol , vol.32 , pp. 319-323
    • Wasserman, D.H.1    Ayala, J.E.2
  • 34
    • 4544355934 scopus 로고    scopus 로고
    • Mitochondrial bound hexokinase activity as a preventive antioxidant defense: Steadystate ADP formation as a regulatory mechanism of membrane potential and reactive oxygen species generation in mitochondria
    • da-Silva WS, Gómez-Puyou A, de Gómez-Puyou MT, et al. Mitochondrial bound hexokinase activity as a preventive antioxidant defense: steadystate ADP formation as a regulatory mechanism of membrane potential and reactive oxygen species generation in mitochondria. J Biol Chem 2004; 279:39846-39855
    • (2004) J Biol Chem , vol.279 , pp. 39846-39855
    • Da-Silva, W.S.1    Gómez-Puyou, A.2    De Gómez-Puyou, M.T.3
  • 35
    • 34249660144 scopus 로고    scopus 로고
    • TXNIP regulates peripheral glucose metabolism in humans
    • Parikh H, Carlsson E, Chutkow WA, et al. TXNIP regulates peripheral glucose metabolism in humans. PLoS Med 2007;4:e158
    • (2007) PLoS Med , vol.4
    • Parikh, H.1    Carlsson, E.2    Chutkow, W.A.3
  • 36
    • 34648813720 scopus 로고    scopus 로고
    • ROS as signalling molecules: Mechanisms that generate specificity in ROS homeostasis
    • D'Autréaux B, Toledano MB. ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis. Nat Rev Mol Cell Biol 2007;8: 813-824
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 813-824
    • D'Autréaux, B.1    Toledano, M.B.2
  • 37
    • 67650815430 scopus 로고    scopus 로고
    • Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans
    • Anderson EJ, Lustig ME, Boyle KE, et al. Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans. J Clin Invest 2009;119:573-581
    • (2009) J Clin Invest , vol.119 , pp. 573-581
    • Anderson, E.J.1    Lustig, M.E.2    Boyle, K.E.3
  • 38
    • 78649497300 scopus 로고    scopus 로고
    • Targeted expression of catalase to mitochondria prevents age-associated reductions in mitochondrial function and insulin resistance
    • Lee HY, Choi CS, Birkenfeld AL, et al. Targeted expression of catalase to mitochondria prevents age-associated reductions in mitochondrial function and insulin resistance. Cell Metab 2010;12:668-674
    • (2010) Cell Metab , vol.12 , pp. 668-674
    • Lee, H.Y.1    Choi, C.S.2    Birkenfeld, A.L.3
  • 39
    • 28844461131 scopus 로고    scopus 로고
    • Proposed mechanisms for the induction of insulin resistance by oxidative stress
    • Bloch-Damti A, Bashan N. Proposed mechanisms for the induction of insulin resistance by oxidative stress. Antioxid Redox Signal 2005;7:1553-1567
    • (2005) Antioxid Redox Signal , vol.7 , pp. 1553-1567
    • Bloch-Damti, A.1    Bashan, N.2
  • 40
    • 78049407128 scopus 로고    scopus 로고
    • Cardiolipin remodeling by ALCAT1 links oxidative stress and mitochondrial dysfunction to obesity
    • Li J, Romestaing C, Han X, et al. Cardiolipin remodeling by ALCAT1 links oxidative stress and mitochondrial dysfunction to obesity. Cell Metab 2010;12:154-165
    • (2010) Cell Metab , vol.12 , pp. 154-165
    • Li, J.1    Romestaing, C.2    Han, X.3
  • 41
    • 78651393239 scopus 로고    scopus 로고
    • A role for mitochondria in NLRP3 inflammasome activation
    • Zhou R, Yazdi AS, Menu P, Tschopp J. A role for mitochondria in NLRP3 inflammasome activation. Nature 2011;469:221-225
    • (2011) Nature , vol.469 , pp. 221-225
    • Zhou, R.1    Yazdi, A.S.2    Menu, P.3    Tschopp, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.