Why cytoplasmic signalling proteins should be recruited to cell membranes

Trends in Cell Biology

Volumn 10, Issue 5, 2000, Pages 173-178

  Kholodenko, Boris N ^a   Hoek, Jan B ^a   Westerhoff, Hans V ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; MEMBRANE PROTEIN;

CELL MEMBRANE; CELLULAR DISTRIBUTION; CYTOPLASM; DIFFUSION; HYPOTHESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN TRANSPORT; RECEPTOR BINDING; SHORT SURVEY; SIGNAL TRANSDUCTION;

ANIMALS; CELL MEMBRANE; CYTOPLASM; HUMANS; KINETICS; MEMBRANE PROTEINS; MODELS, CHEMICAL; PROTEIN BINDING; RECEPTOR PROTEIN-TYROSINE KINASES; SIGNAL TRANSDUCTION;

EID: 0034194467     PISSN: 09628924     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0962-8924(00)01741-4     Document Type: Note

References (30)

1. 1 Mochly-Rosen, D. (1995) Localization of protein kinases by anchoring proteins: a theme in signal transduction. Science 268, 247-251
2. 2 McLaughlin, S. and Aderem, A. (1995) The myristoyl-electrostatic switch: a modulator of reversible protein membrane interactions. Trends Biochem. Sci. 20, 272-276
3. 3 Carraway, K.L. and Carraway, C.A. (1995) Signalling, mitogenesis and the cytoskeleton: where the action is. BioEssays 17, 171-175
4. 4 Egan, S.E. et al. (1993) Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation. Nature 363, 45-51
5. 5 Buday, L. and Downward, J. (1993) Epidermal growth factor regulates p21 ras through the formation of a complex of receptor, Grb2 adaptor protein, and Sos nucleotide exchange factor. Cell 73, 611-620
6. 6 McCormick, F. (1993) Signal transduction. How receptors turn Ras on. Nature 363, 15-16
7. 7 Aronheim, A. et al. (1994) Membrane targeting of the nucleotide exchange factor Sos is sufficient for activating the Ras signalling pathway. Cell 78, 949-961
8. 8 Joneson, T. and Bar-Sagi, D. (1997) Ras effectors and their role in mitogenesis and oncogenesis. J. Mol. Med. 75, 587-593
9. 9 Adam, G. and Delbrück, M. (1968) Reduction of dimensionality in biological diffusion processes. Struct. Chem. Mol. Biol. 198-215
10. 10 Berg, H.C. and Purcell, E.M. (1977) Physics of chemoreception. Biophys. J. 20, 193-219
11. 11 Wang, D. et al. (1992) Reaction rate enhancement by surface diffusion of adsorbates. Biophys. Chem. 43, 117-137
12. 12 Axelrod, D. and Wang, M.D. (1994) Reduction-of-dimensionality kinetics at reaction-limited cell surface receptors. Biophys. J. 66, 588-600
13. 13 Westerhoff, H.V. and Welch, G.R. (1992) Enzyme organization and the direction of metabolic flow: physicochemical considerations. Curr. Top. Cell. Regul. 33, 361-390
14. 14 Cherry, R.J. (1979) Rotational and lateral diffusion of membrane proteins. Biochim. Biophys. Acta 559, 289-327
15. 15 Kusumi, A. et al. (1993) Confined lateral diffusion of membrane receptors as studied by single particle tracking (nanovid microscopy). Effects of calcium-induced differentiation in cultured epithelial cells. Biophys. J. 65, 2021-2040
16. 16 Brown, G.C. and Kholodenko, B.N. (1999) Spatial gradients of cellular phospho-proteins. FEBS Lett. 457, 452-454
17. 17 Bray, D. (1998) Signalling complexes: biophysical constraints on intracellular communication. Annu. Rev. Biophys. Biomol. Struct. 27, 59-75
18. 18 Torney, D.C. and McConnell, H.M. (1983) Diffusion-limited reaction rate theory for two-dimensional systems. Proc. R. Soc. London Ser. A 387, 147-170
19. 19 Lamb, T.D. and Pugh, E.N., Jr. (1992) A quantitative account of the activation steps involved in phototransduction in amphibian photoreceptors. J. Physiol. 449, 719-758
20. 20 Haugh, J.M. and Lauffenburger, D.A. (1997) Physical modulation of intracellular signalling processes by locational regulation. Biophys. J. 72, 2014-2031
21. 21 Rietveld, A. and Simons, K. (1998) The differential miscibility of lipids as the basis for the formation of functional membrane rafts. Biochim. Biophys. Acta 1376, 467-479
22. 22 Rohwer, J.M. et al. (1998) Implications of molecular crowding for signal transduction and metabolite channeling. Proc. Natl. Acad. Sei. U. S. A. 95, 10547-10552
23. 23 Kholodenko, B.N. et al. (1999) Quantification of short term signalling by the epidermal growth factor receptor. J. Biol. Chem. 274, 30169-30181
24. 24 Panayotou, G. et al. (1993) Interactions between SH2 domains and tyrosine-phosphorylated platelet-derived growth factor beta-receptor sequences: analysis of kinetic parameters by a novel biosensor-based approach. Mol. Cell. Biol. 13, 3567-3576
25. 25 Ladbury, J.E. et al. (1995) Measurement of the binding of tyrosyl phosphopeptides to SH2 domains: a reappraisal. Proc. Natl. Acad. Sci. U. S. A. 92, 3199-3203
26. 26 Ferrell, J.E., Jr. (1998) How responses get more switch-like as you move down a protein kinase cascade. Trends Biochem. Sci. 22, 288-289
27. 27 Kholodenko, B.N. et al. (1997) Quantification of information transfer via cellular signal transduction pathways. FEBS Lett. 414, 430-434
28. 28 Ferrell, J.E., Jr. (1998) How regulated protein translocation can produce switch-like responses. Trends Biochem. Sci. 23, 461-465
29. 29 Cox, A.D. and Der, C.J. (1997) Farnesyltransferase inhibitors and cancer treatment: targeting simply Ras? Biochim. Biophys. Acta 1333, F51-F71
30. 30 Kouhara, H. et al. (1997) A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signalling pathway. Cell 89, 693-702