-
1
-
-
0014013130
-
Apparent co-operative effect of acetyl-CoA on sheep kidney pyruvate carboxylase
-
G.J. Barritt, D.B. Keech, and A.M. Ling Apparent co-operative effect of acetyl-CoA on sheep kidney pyruvate carboxylase Biochem. Biophys. Res. Commun. 24 1966 476 481
-
(1966)
Biochem. Biophys. Res. Commun.
, vol.24
, pp. 476-481
-
-
Barritt, G.J.1
Keech, D.B.2
Ling, A.M.3
-
2
-
-
0027337194
-
Determination of the 13C-labeling pattern of glutamate by gas chromatography-mass spectrometry
-
M. Beylot, F. David, and H. Brunengraber Determination of the 13C-labeling pattern of glutamate by gas chromatography-mass spectrometry Anal. Biochem. 212 1993 532 536
-
(1993)
Anal. Biochem.
, vol.212
, pp. 532-536
-
-
Beylot, M.1
David, F.2
Brunengraber, H.3
-
3
-
-
78149373656
-
Projection of the year 2050 burden of diabetes in the US adult population: Dynamic modeling of incidence, mortality, and prediabetes prevalence
-
J.P. Boyle, T.J. Thompson, E.W. Gregg, L.E. Barker, and D.F. Williamson Projection of the year 2050 burden of diabetes in the US adult population: dynamic modeling of incidence, mortality, and prediabetes prevalence Popul. Health Metr. 8 2010 29
-
(2010)
Popul. Health Metr.
, vol.8
, pp. 29
-
-
Boyle, J.P.1
Thompson, T.J.2
Gregg, E.W.3
Barker, L.E.4
Williamson, D.F.5
-
4
-
-
0029044581
-
Growth hormone reduces glucose transport but not GLUT-1 or GLUT-4 in adult and old rats
-
G.D. Cartee, and E.E. Bohn Growth hormone reduces glucose transport but not GLUT-1 or GLUT-4 in adult and old rats Am. J. Physiol. 268 1995 E902 E909
-
(1995)
Am. J. Physiol.
, vol.268
, pp. E902-E909
-
-
Cartee, G.D.1
Bohn, E.E.2
-
5
-
-
0014424641
-
The regulation of yeast pyruvate carboxylase by acetyl-coenzyme A and L-aspartate
-
J.J. Cazzulo, and A.O. Stoppani The regulation of yeast pyruvate carboxylase by acetyl-coenzyme A and L-aspartate Arch. Biochem. Biophys. 127 1968 563 567
-
(1968)
Arch. Biochem. Biophys.
, vol.127
, pp. 563-567
-
-
Cazzulo, J.J.1
Stoppani, A.O.2
-
6
-
-
41549123672
-
Adipose-specific disruption of signal transducer and activator of transcription 3 increases body weight and adiposity
-
E.R. Cernkovich, J. Deng, M.C. Bond, T.P. Combs, and J.B. Harp Adipose-specific disruption of signal transducer and activator of transcription 3 increases body weight and adiposity Endocrinology 149 2008 1581 1590
-
(2008)
Endocrinology
, vol.149
, pp. 1581-1590
-
-
Cernkovich, E.R.1
Deng, J.2
Bond, M.C.3
Combs, T.P.4
Harp, J.B.5
-
7
-
-
0020554505
-
Regulation of mitochondrial pyruvate carboxylation in isolated hepatocytes by acute insulin treatment
-
A.B. Chisholm, E.H. Allan, and M.A. Titheradge Regulation of mitochondrial pyruvate carboxylation in isolated hepatocytes by acute insulin treatment Biochem. J. 214 1983 451 458
-
(1983)
Biochem. J.
, vol.214
, pp. 451-458
-
-
Chisholm, A.B.1
Allan, E.H.2
Titheradge, M.A.3
-
8
-
-
0014004651
-
The participation of acetyl-CoA in pyruvate carboxylase
-
T.G. Cooper, and C.R. Benedict The participation of acetyl-CoA in pyruvate carboxylase Biochem. Biophys. Res. Commun. 22 1966 285 290
-
(1966)
Biochem. Biophys. Res. Commun.
, vol.22
, pp. 285-290
-
-
Cooper, T.G.1
Benedict, C.R.2
-
9
-
-
85005717647
-
A method for the extraction of glycogen and metabolites from a single muscle sample
-
R.H. Dalrymple, and D. Hamm A method for the extraction of glycogen and metabolites from a single muscle sample Int. J. Food Sci. Technol. 8 1973 439 444
-
(1973)
Int. J. Food Sci. Technol.
, vol.8
, pp. 439-444
-
-
Dalrymple, R.H.1
Hamm, D.2
-
10
-
-
73249136971
-
Effects of insulin on the metabolic control of hepatic gluconeogenesis in vivo
-
D.S. Edgerton, C.J. Ramnanan, C.A. Grueter, K.M. Johnson, M. Lautz, D.W. Neal, P.E. Williams, and A.D. Cherrington Effects of insulin on the metabolic control of hepatic gluconeogenesis in vivo Diabetes 58 2009 2766 2775
-
(2009)
Diabetes
, vol.58
, pp. 2766-2775
-
-
Edgerton, D.S.1
Ramnanan, C.J.2
Grueter, C.A.3
Johnson, K.M.4
Lautz, M.5
Neal, D.W.6
Williams, P.E.7
Cherrington, A.D.8
-
11
-
-
0035049305
-
Circulating interleukin 6 levels, blood pressure, and insulin sensitivity in apparently healthy men and women
-
J.M. Fernandez-Real, M. Vayreda, C. Richart, C. Gutierrez, M. Broch, J. Vendrell, and W. Ricart Circulating interleukin 6 levels, blood pressure, and insulin sensitivity in apparently healthy men and women J. Clin. Endocrinol. Metab. 86 2001 1154 1159
-
(2001)
J. Clin. Endocrinol. Metab.
, vol.86
, pp. 1154-1159
-
-
Fernandez-Real, J.M.1
Vayreda, M.2
Richart, C.3
Gutierrez, C.4
Broch, M.5
Vendrell, J.6
Ricart, W.7
-
13
-
-
34249682779
-
Interleukin-6 directly increases glucose metabolism in resting human skeletal muscle
-
S. Glund, A. Deshmukh, Y.C. Long, T. Moller, H.A. Koistinen, K. Caidahl, J.R. Zierath, and A. Krook Interleukin-6 directly increases glucose metabolism in resting human skeletal muscle Diabetes 56 2007 1630 1637
-
(2007)
Diabetes
, vol.56
, pp. 1630-1637
-
-
Glund, S.1
Deshmukh, A.2
Long, Y.C.3
Moller, T.4
Koistinen, H.A.5
Caidahl, K.6
Zierath, J.R.7
Krook, A.8
-
14
-
-
0028922433
-
A major role for the protein tyrosine kinase JAK1 in the JAK/STAT signal transduction pathway in response to interleukin-6
-
D. Guschin, N. Rogers, J. Briscoe, B. Witthuhn, D. Watling, F. Horn, S. Pellegrini, K. Yasukawa, P. Heinrich, and G.R. Stark A major role for the protein tyrosine kinase JAK1 in the JAK/STAT signal transduction pathway in response to interleukin-6 EMBO J. 14 1995 1421 1429
-
(1995)
EMBO J.
, vol.14
, pp. 1421-1429
-
-
Guschin, D.1
Rogers, N.2
Briscoe, J.3
Witthuhn, B.4
Watling, D.5
Horn, F.6
Pellegrini, S.7
Yasukawa, K.8
Heinrich, P.9
Stark, G.R.10
-
15
-
-
84922754155
-
Integrated control of hepatic lipogenesis versus glucose production requires FoxO transcription factors
-
R.A. Haeusler, K. Hartil, B. Vaitheesvaran, I. Arrieta-Cruz, C.M. Knight, J.R. Cook, H.L. Kammoun, M.A. Febbraio, R. Gutierrez-Juarez, I.J. Kurland, and D. Accili Integrated control of hepatic lipogenesis versus glucose production requires FoxO transcription factors Nat. Commun. 5 2014 5190
-
(2014)
Nat. Commun.
, vol.5
, pp. 5190
-
-
Haeusler, R.A.1
Hartil, K.2
Vaitheesvaran, B.3
Arrieta-Cruz, I.4
Knight, C.M.5
Cook, J.R.6
Kammoun, H.L.7
Febbraio, M.A.8
Gutierrez-Juarez, R.9
Kurland, I.J.10
Accili, D.11
-
16
-
-
84872142459
-
JNK expression by macrophages promotes obesity-induced insulin resistance and inflammation
-
M.S. Han, D.Y. Jung, C. Morel, S.A. Lakhani, J.K. Kim, R.A. Flavell, and R.J. Davis JNK expression by macrophages promotes obesity-induced insulin resistance and inflammation Science 339 2013 218 222
-
(2013)
Science
, vol.339
, pp. 218-222
-
-
Han, M.S.1
Jung, D.Y.2
Morel, C.3
Lakhani, S.A.4
Kim, J.K.5
Flavell, R.A.6
Davis, R.J.7
-
17
-
-
0017755794
-
Studies on the mechanism of insulin action: Basic concepts and clinical implications
-
K.D. Hepp Studies on the mechanism of insulin action: basic concepts and clinical implications Diabetologia 13 1977 177 186
-
(1977)
Diabetologia
, vol.13
, pp. 177-186
-
-
Hepp, K.D.1
-
18
-
-
77950264425
-
Direct insulin and leptin action on pro-opiomelanocortin neurons is required for normal glucose homeostasis and fertility
-
J.W. Hill, C.F. Elias, M. Fukuda, K.W. Williams, E.D. Berglund, W.L. Holland, Y.R. Cho, J.C. Chuang, Y. Xu, and M. Choi Direct insulin and leptin action on pro-opiomelanocortin neurons is required for normal glucose homeostasis and fertility Cell Metab. 11 2010 286 297
-
(2010)
Cell Metab.
, vol.11
, pp. 286-297
-
-
Hill, J.W.1
Elias, C.F.2
Fukuda, M.3
Williams, K.W.4
Berglund, E.D.5
Holland, W.L.6
Cho, Y.R.7
Chuang, J.C.8
Xu, Y.9
Choi, M.10
-
19
-
-
77956772446
-
Sensing the fuels: Glucose and lipid signaling in the CNS controlling energy homeostasis
-
S.D. Jordan, A.C. Könner, and J.C. Brüning Sensing the fuels: glucose and lipid signaling in the CNS controlling energy homeostasis Cell. Mol. Life Sci. 67 2010 3255 3273
-
(2010)
Cell. Mol. Life Sci.
, vol.67
, pp. 3255-3273
-
-
Jordan, S.D.1
Könner, A.C.2
Brüning, J.C.3
-
20
-
-
0033139237
-
Circulating levels of interleukin-6, its soluble receptor and interleukin-6/interleukin-6 receptor complexes in patients with type 2 diabetes mellitus
-
S. Kado, T. Nagase, and N. Nagata Circulating levels of interleukin-6, its soluble receptor and interleukin-6/interleukin-6 receptor complexes in patients with type 2 diabetes mellitus Acta Diabetol. 36 1999 67 72
-
(1999)
Acta Diabetol.
, vol.36
, pp. 67-72
-
-
Kado, S.1
Nagase, T.2
Nagata, N.3
-
21
-
-
84896495719
-
Pathophysiology and treatment of type 2 diabetes: Perspectives on the past, present, and future
-
S.E. Kahn, M.E. Cooper, and S. Del Prato Pathophysiology and treatment of type 2 diabetes: perspectives on the past, present, and future Lancet 383 2014 1068 1083
-
(2014)
Lancet
, vol.383
, pp. 1068-1083
-
-
Kahn, S.E.1
Cooper, M.E.2
Del Prato, S.3
-
22
-
-
78651126425
-
Pyruvate Carboxylase. Ii. Properties
-
D.B. Keech, and M.F. Utter Pyruvate Carboxylase. Ii. Properties J. Biol. Chem. 238 1963 2609 2614
-
(1963)
J. Biol. Chem.
, vol.238
, pp. 2609-2614
-
-
Keech, D.B.1
Utter, M.F.2
-
23
-
-
0000635987
-
Acceleration of Renal Gluconeogenesis by Ketone Bodies and Fatty Acids
-
H.A. Krebs, R.N. Speake, and R. Hems Acceleration of Renal Gluconeogenesis by Ketone Bodies and Fatty Acids Biochem. J. 94 1965 712 720
-
(1965)
Biochem. J.
, vol.94
, pp. 712-720
-
-
Krebs, H.A.1
Speake, R.N.2
Hems, R.3
-
24
-
-
80053627289
-
Cellular mechanism of insulin resistance in nonalcoholic fatty liver disease
-
N. Kumashiro, D.M. Erion, D. Zhang, M. Kahn, S.A. Beddow, X. Chu, C.D. Still, G.S. Gerhard, X. Han, and J. Dziura Cellular mechanism of insulin resistance in nonalcoholic fatty liver disease Proc. Natl. Acad. Sci. USA 108 2011 16381 16385
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 16381-16385
-
-
Kumashiro, N.1
Erion, D.M.2
Zhang, D.3
Kahn, M.4
Beddow, S.A.5
Chu, X.6
Still, C.D.7
Gerhard, G.S.8
Han, X.9
Dziura, J.10
-
25
-
-
77956383646
-
Cellularity and adipogenic profile of the abdominal subcutaneous adipose tissue from obese adolescents: Association with insulin resistance and hepatic steatosis
-
R. Kursawe, M. Eszlinger, D. Narayan, T. Liu, M. Bazuine, A.M. Cali, E. D'Adamo, M. Shaw, B. Pierpont, and G.I. Shulman Cellularity and adipogenic profile of the abdominal subcutaneous adipose tissue from obese adolescents: association with insulin resistance and hepatic steatosis Diabetes 59 2010 2288 2296
-
(2010)
Diabetes
, vol.59
, pp. 2288-2296
-
-
Kursawe, R.1
Eszlinger, M.2
Narayan, D.3
Liu, T.4
Bazuine, M.5
Cali, A.M.6
D'Adamo, E.7
Shaw, M.8
Pierpont, B.9
Shulman, G.I.10
-
26
-
-
0029936779
-
Hepatic glucose production is regulated both by direct hepatic and extrahepatic effects of insulin in humans
-
G.F. Lewis, B. Zinman, Y. Groenewoud, M. Vranic, and A. Giacca Hepatic glucose production is regulated both by direct hepatic and extrahepatic effects of insulin in humans Diabetes 45 1996 454 462
-
(1996)
Diabetes
, vol.45
, pp. 454-462
-
-
Lewis, G.F.1
Zinman, B.2
Groenewoud, Y.3
Vranic, M.4
Giacca, A.5
-
27
-
-
77449144768
-
Divergent regulation of energy expenditure and hepatic glucose production by insulin receptor in agouti-related protein and POMC neurons
-
H.V. Lin, L. Plum, H. Ono, R. Gutiérrez-Juárez, M. Shanabrough, E. Borok, T.L. Horvath, L. Rossetti, and D. Accili Divergent regulation of energy expenditure and hepatic glucose production by insulin receptor in agouti-related protein and POMC neurons Diabetes 59 2010 337 346
-
(2010)
Diabetes
, vol.59
, pp. 337-346
-
-
Lin, H.V.1
Plum, L.2
Ono, H.3
Gutiérrez-Juárez, R.4
Shanabrough, M.5
Borok, E.6
Horvath, T.L.7
Rossetti, L.8
Accili, D.9
-
28
-
-
84857934301
-
Insulin regulates liver metabolism in vivo in the absence of hepatic Akt and Foxo1
-
M. Lu, M. Wan, K.F. Leavens, Q. Chu, B.R. Monks, S. Fernandez, R.S. Ahima, K. Ueki, C.R. Kahn, and M.J. Birnbaum Insulin regulates liver metabolism in vivo in the absence of hepatic Akt and Foxo1 Nat. Med. 18 2012 388 395
-
(2012)
Nat. Med.
, vol.18
, pp. 388-395
-
-
Lu, M.1
Wan, M.2
Leavens, K.F.3
Chu, Q.4
Monks, B.R.5
Fernandez, S.6
Ahima, R.S.7
Ueki, K.8
Kahn, C.R.9
Birnbaum, M.J.10
-
29
-
-
0028296179
-
Association of transcription factor APRF and protein kinase Jak1 with the interleukin-6 signal transducer gp130
-
C. Lütticken, U.M. Wegenka, J. Yuan, J. Buschmann, C. Schindler, A. Ziemiecki, A.G. Harpur, A.F. Wilks, K. Yasukawa, and T. Taga Association of transcription factor APRF and protein kinase Jak1 with the interleukin-6 signal transducer gp130 Science 263 1994 89 92
-
(1994)
Science
, vol.263
, pp. 89-92
-
-
Lütticken, C.1
Wegenka, U.M.2
Yuan, J.3
Buschmann, J.4
Schindler, C.5
Ziemiecki, A.6
Harpur, A.G.7
Wilks, A.F.8
Yasukawa, K.9
Taga, T.10
-
30
-
-
84879299547
-
Systems biology of adipose tissue metabolism: Regulation of growth, signaling and inflammation
-
S. Manteiga, K. Choi, A. Jayaraman, and K. Lee Systems biology of adipose tissue metabolism: regulation of growth, signaling and inflammation Wiley Interdiscip Rev Syst Biol Med 5 2013 425 447
-
(2013)
Wiley Interdiscip Rev Syst Biol Med
, vol.5
, pp. 425-447
-
-
Manteiga, S.1
Choi, K.2
Jayaraman, A.3
Lee, K.4
-
31
-
-
0030735542
-
Subcutaneous adipose tissue releases interleukin-6, but not tumor necrosis factor-alpha, in vivo
-
V. Mohamed-Ali, S. Goodrick, A. Rawesh, D.R. Katz, J.M. Miles, J.S. Yudkin, S. Klein, and S.W. Coppack Subcutaneous adipose tissue releases interleukin-6, but not tumor necrosis factor-alpha, in vivo J. Clin. Endocrinol. Metab. 82 1997 4196 4200
-
(1997)
J. Clin. Endocrinol. Metab.
, vol.82
, pp. 4196-4200
-
-
Mohamed-Ali, V.1
Goodrick, S.2
Rawesh, A.3
Katz, D.R.4
Miles, J.M.5
Yudkin, J.S.6
Klein, S.7
Coppack, S.W.8
-
32
-
-
0036913187
-
Hypothalamic insulin signaling is required for inhibition of glucose production
-
S. Obici, B.B. Zhang, G. Karkanias, and L. Rossetti Hypothalamic insulin signaling is required for inhibition of glucose production Nat. Med. 8 2002 1376 1382
-
(2002)
Nat. Med.
, vol.8
, pp. 1376-1382
-
-
Obici, S.1
Zhang, B.B.2
Karkanias, G.3
Rossetti, L.4
-
33
-
-
77951918926
-
Macrophages, inflammation, and insulin resistance
-
J.M. Olefsky, and C.K. Glass Macrophages, inflammation, and insulin resistance Annu. Rev. Physiol. 72 2010 219 246
-
(2010)
Annu. Rev. Physiol.
, vol.72
, pp. 219-246
-
-
Olefsky, J.M.1
Glass, C.K.2
-
34
-
-
84887432240
-
Reversal of hypertriglyceridemia, fatty liver disease, and insulin resistance by a liver-targeted mitochondrial uncoupler
-
R.J. Perry, T. Kim, X.M. Zhang, H.Y. Lee, D. Pesta, V.B. Popov, D. Zhang, Y. Rahimi, M.J. Jurczak, and G.W. Cline Reversal of hypertriglyceridemia, fatty liver disease, and insulin resistance by a liver-targeted mitochondrial uncoupler Cell Metab. 18 2013 740 748
-
(2013)
Cell Metab.
, vol.18
, pp. 740-748
-
-
Perry, R.J.1
Kim, T.2
Zhang, X.M.3
Lee, H.Y.4
Pesta, D.5
Popov, V.B.6
Zhang, D.7
Rahimi, Y.8
Jurczak, M.J.9
Cline, G.W.10
-
35
-
-
84904000735
-
Leptin reverses diabetes by suppression of the hypothalamic-pituitary-adrenal axis
-
R.J. Perry, X.M. Zhang, D. Zhang, N. Kumashiro, J.P. Camporez, G.W. Cline, D.L. Rothman, and G.I. Shulman Leptin reverses diabetes by suppression of the hypothalamic-pituitary-adrenal axis Nat. Med. 20 2014 759 763
-
(2014)
Nat. Med.
, vol.20
, pp. 759-763
-
-
Perry, R.J.1
Zhang, X.M.2
Zhang, D.3
Kumashiro, N.4
Camporez, J.P.5
Cline, G.W.6
Rothman, D.L.7
Shulman, G.I.8
-
36
-
-
33845315534
-
Increased prevalence of insulin resistance and nonalcoholic fatty liver disease in Asian-Indian men
-
K.F. Petersen, S. Dufour, J. Feng, D. Befroy, J. Dziura, C. Dalla Man, C. Cobelli, and G.I. Shulman Increased prevalence of insulin resistance and nonalcoholic fatty liver disease in Asian-Indian men Proc. Natl. Acad. Sci. USA 103 2006 18273 18277
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 18273-18277
-
-
Petersen, K.F.1
Dufour, S.2
Feng, J.3
Befroy, D.4
Dziura, J.5
Dalla Man, C.6
Cobelli, C.7
Shulman, G.I.8
-
37
-
-
0030731621
-
NIDDM as a disease of the innate immune system: Association of acute-phase reactants and interleukin-6 with metabolic syndrome X
-
J.C. Pickup, M.B. Mattock, G.D. Chusney, and D. Burt NIDDM as a disease of the innate immune system: association of acute-phase reactants and interleukin-6 with metabolic syndrome X Diabetologia 40 1997 1286 1292
-
(1997)
Diabetologia
, vol.40
, pp. 1286-1292
-
-
Pickup, J.C.1
Mattock, M.B.2
Chusney, G.D.3
Burt, D.4
-
38
-
-
0026520193
-
Molecular physiology of the regulation of hepatic gluconeogenesis and glycolysis
-
S.J. Pilkis, and D.K. Granner Molecular physiology of the regulation of hepatic gluconeogenesis and glycolysis Annu. Rev. Physiol. 54 1992 885 909
-
(1992)
Annu. Rev. Physiol.
, vol.54
, pp. 885-909
-
-
Pilkis, S.J.1
Granner, D.K.2
-
39
-
-
0032810949
-
A critical evaluation of mass isotopomer distribution analysis of gluconeogenesis in vivo
-
S.F. Previs, G.W. Cline, and G.I. Shulman A critical evaluation of mass isotopomer distribution analysis of gluconeogenesis in vivo Am. J. Physiol. 277 1999 E154 E160
-
(1999)
Am. J. Physiol.
, vol.277
, pp. E154-E160
-
-
Previs, S.F.1
Cline, G.W.2
Shulman, G.I.3
-
40
-
-
0029861999
-
Causal linkage between insulin suppression of lipolysis and suppression of liver glucose output in dogs
-
K. Rebrin, G.M. Steil, S.D. Mittelman, and R.N. Bergman Causal linkage between insulin suppression of lipolysis and suppression of liver glucose output in dogs J. Clin. Invest. 98 1996 741 749
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 741-749
-
-
Rebrin, K.1
Steil, G.M.2
Mittelman, S.D.3
Bergman, R.N.4
-
41
-
-
84899140315
-
Inflammasomes and metabolic disorders: Old genes in modern diseases
-
G.R. Robbins, H. Wen, and J.P. Ting Inflammasomes and metabolic disorders: old genes in modern diseases Mol. Cell 54 2014 297 308
-
(2014)
Mol. Cell
, vol.54
, pp. 297-308
-
-
Robbins, G.R.1
Wen, H.2
Ting, J.P.3
-
42
-
-
84857861919
-
Mechanisms for insulin resistance: Common threads and missing links
-
V.T. Samuel, and G.I. Shulman Mechanisms for insulin resistance: common threads and missing links Cell 148 2012 852 871
-
(2012)
Cell
, vol.148
, pp. 852-871
-
-
Samuel, V.T.1
Shulman, G.I.2
-
43
-
-
18244372432
-
Mechanisms of insulin resistance in humans and possible links with inflammation
-
D.B. Savage, K.F. Petersen, and G.I. Shulman Mechanisms of insulin resistance in humans and possible links with inflammation Hypertension 45 2005 828 833
-
(2005)
Hypertension
, vol.45
, pp. 828-833
-
-
Savage, D.B.1
Petersen, K.F.2
Shulman, G.I.3
-
44
-
-
84887347937
-
Cooperation between brain and islet in glucose homeostasis and diabetes
-
M.W. Schwartz, R.J. Seeley, M.H. Tschöp, S.C. Woods, G.J. Morton, M.G. Myers, and D. D'Alessio Cooperation between brain and islet in glucose homeostasis and diabetes Nature 503 2013 59 66
-
(2013)
Nature
, vol.503
, pp. 59-66
-
-
Schwartz, M.W.1
Seeley, R.J.2
Tschöp, M.H.3
Woods, S.C.4
Morton, G.J.5
Myers, M.G.6
D'Alessio, D.7
-
45
-
-
84918819322
-
Ectopic fat in insulin resistance, dyslipidemia, and cardiometabolic disease
-
G.I. Shulman Ectopic fat in insulin resistance, dyslipidemia, and cardiometabolic disease N. Engl. J. Med. 371 2014 1131 1141
-
(2014)
N. Engl. J. Med.
, vol.371
, pp. 1131-1141
-
-
Shulman, G.I.1
-
46
-
-
0028281794
-
Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components
-
N. Stahl, T.G. Boulton, T. Farruggella, N.Y. Ip, S. Davis, B.A. Witthuhn, F.W. Quelle, O. Silvennoinen, G. Barbieri, and S. Pellegrini Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components Science 263 1994 92 95
-
(1994)
Science
, vol.263
, pp. 92-95
-
-
Stahl, N.1
Boulton, T.G.2
Farruggella, T.3
Ip, N.Y.4
Davis, S.5
Witthuhn, B.A.6
Quelle, F.W.7
Silvennoinen, O.8
Barbieri, G.9
Pellegrini, S.10
-
47
-
-
0000648085
-
Influences of glucose loading and of injected insulin on hepatic glucose output
-
R. Steele Influences of glucose loading and of injected insulin on hepatic glucose output Ann. N Y Acad. Sci. 82 1959 420 430
-
(1959)
Ann. N y Acad. Sci.
, vol.82
, pp. 420-430
-
-
Steele, R.1
-
48
-
-
84914706611
-
Disruption of multisystem responses to stress in type 2 diabetes: Investigating the dynamics of allostatic load
-
A. Steptoe, R.A. Hackett, A.I. Lazzarino, S. Bostock, R. La Marca, L.A. Carvalho, and M. Hamer Disruption of multisystem responses to stress in type 2 diabetes: investigating the dynamics of allostatic load Proc. Natl. Acad. Sci. USA 111 2014 15693 15698
-
(2014)
Proc. Natl. Acad. Sci. USA
, vol.111
, pp. 15693-15698
-
-
Steptoe, A.1
Hackett, R.A.2
Lazzarino, A.I.3
Bostock, S.4
La Marca, R.5
Carvalho, L.A.6
Hamer, M.7
-
49
-
-
0034454417
-
Hormone replacement therapy and interrelation between serum interleukin-6 and body mass index in postmenopausal women: A population-based study
-
R.H. Straub, H.W. Hense, T. Andus, J. Schölmerich, G.A. Riegger, and H. Schunkert Hormone replacement therapy and interrelation between serum interleukin-6 and body mass index in postmenopausal women: a population-based study J. Clin. Endocrinol. Metab. 85 2000 1340 1344
-
(2000)
J. Clin. Endocrinol. Metab.
, vol.85
, pp. 1340-1344
-
-
Straub, R.H.1
Hense, H.W.2
Andus, T.3
Schölmerich, J.4
Riegger, G.A.5
Schunkert, H.6
-
50
-
-
77954672503
-
Adipose tissue macrophages: Their role in adipose tissue remodeling
-
T. Suganami, and Y. Ogawa Adipose tissue macrophages: their role in adipose tissue remodeling J. Leukoc. Biol. 88 2010 33 39
-
(2010)
J. Leukoc. Biol.
, vol.88
, pp. 33-39
-
-
Suganami, T.1
Ogawa, Y.2
-
51
-
-
84879596112
-
Thyroid hormone receptor-β agonists prevent hepatic steatosis in fat-fed rats but impair insulin sensitivity via discrete pathways
-
D.F. Vatner, D. Weismann, S.A. Beddow, N. Kumashiro, D.M. Erion, X.H. Liao, G.J. Grover, P. Webb, K.J. Phillips, and R.E. Weiss Thyroid hormone receptor-β agonists prevent hepatic steatosis in fat-fed rats but impair insulin sensitivity via discrete pathways Am. J. Physiol. Endocrinol. Metab. 305 2013 E89 E100
-
(2013)
Am. J. Physiol. Endocrinol. Metab.
, vol.305
, pp. E89-E100
-
-
Vatner, D.F.1
Weismann, D.2
Beddow, S.A.3
Kumashiro, N.4
Erion, D.M.5
Liao, X.H.6
Grover, G.J.7
Webb, P.8
Phillips, K.J.9
Weiss, R.E.10
-
52
-
-
3142738035
-
CGI-58 interacts with perilipin and is localized to lipid droplets. Possible involvement of CGI-58 mislocalization in Chanarin-Dorfman syndrome
-
T. Yamaguchi, N. Omatsu, S. Matsushita, and T. Osumi CGI-58 interacts with perilipin and is localized to lipid droplets. Possible involvement of CGI-58 mislocalization in Chanarin-Dorfman syndrome J. Biol. Chem. 279 2004 30490 30497
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 30490-30497
-
-
Yamaguchi, T.1
Omatsu, N.2
Matsushita, S.3
Osumi, T.4
-
53
-
-
34248189053
-
CGI-58 facilitates lipolysis on lipid droplets but is not involved in the vesiculation of lipid droplets caused by hormonal stimulation
-
T. Yamaguchi, N. Omatsu, E. Morimoto, H. Nakashima, K. Ueno, T. Tanaka, K. Satouchi, F. Hirose, and T. Osumi CGI-58 facilitates lipolysis on lipid droplets but is not involved in the vesiculation of lipid droplets caused by hormonal stimulation J. Lipid Res. 48 2007 1078 1089
-
(2007)
J. Lipid Res.
, vol.48
, pp. 1078-1089
-
-
Yamaguchi, T.1
Omatsu, N.2
Morimoto, E.3
Nakashima, H.4
Ueno, K.5
Tanaka, T.6
Satouchi, K.7
Hirose, F.8
Osumi, T.9
-
54
-
-
65549128076
-
Interleukin-6 attenuates insulin-mediated increases in endothelial cell signaling but augments skeletal muscle insulin action via differential effects on tumor necrosis factor-alpha expression
-
D.Y. Yuen, R.M. Dwyer, V.B. Matthews, L. Zhang, B.G. Drew, B. Neill, B.A. Kingwell, M.G. Clark, S. Rattigan, and M.A. Febbraio Interleukin-6 attenuates insulin-mediated increases in endothelial cell signaling but augments skeletal muscle insulin action via differential effects on tumor necrosis factor-alpha expression Diabetes 58 2009 1086 1095
-
(2009)
Diabetes
, vol.58
, pp. 1086-1095
-
-
Yuen, D.Y.1
Dwyer, R.M.2
Matthews, V.B.3
Zhang, L.4
Drew, B.G.5
Neill, B.6
Kingwell, B.A.7
Clark, M.G.8
Rattigan, S.9
Febbraio, M.A.10
-
55
-
-
79958047295
-
Desnutrin/ATGL is regulated by AMPK and is required for a brown adipose phenotype
-
M. Ahmadian, M.J. Abbott, T. Tang, C.S. Hudak, Y. Kim, M. Bruss, M.K. Hellerstein, H.Y. Lee, V.T. Samuel, and G.I. Shulman Desnutrin/ATGL is regulated by AMPK and is required for a brown adipose phenotype Cell Metab. 13 2011 739 748
-
(2011)
Cell Metab.
, vol.13
, pp. 739-748
-
-
Ahmadian, M.1
Abbott, M.J.2
Tang, T.3
Hudak, C.S.4
Kim, Y.5
Bruss, M.6
Hellerstein, M.K.7
Lee, H.Y.8
Samuel, V.T.9
Shulman, G.I.10
-
56
-
-
68949136755
-
Glucose dysregulation and hepatic steatosis in obese adolescents: Is there a link?
-
A.M. Cali, A.M. De Oliveira, H. Kim, S. Chen, M. Reyes-Mugica, S. Escalera, J. Dziura, S.E. Taksali, R. Kursawe, and M. Shaw Glucose dysregulation and hepatic steatosis in obese adolescents: is there a link? Hepatology 49 2009 1896 1903
-
(2009)
Hepatology
, vol.49
, pp. 1896-1903
-
-
Cali, A.M.1
De Oliveira, A.M.2
Kim, H.3
Chen, S.4
Reyes-Mugica, M.5
Escalera, S.6
Dziura, J.7
Taksali, S.E.8
Kursawe, R.9
Shaw, M.10
-
57
-
-
33646462136
-
Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase
-
G. Haemmerle, A. Lass, R. Zimmermann, G. Gorkiewicz, C. Meyer, J. Rozman, G. Heldmaier, R. Maier, C. Theussl, and S. Eder Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase Science 312 2006 734 737
-
(2006)
Science
, vol.312
, pp. 734-737
-
-
Haemmerle, G.1
Lass, A.2
Zimmermann, R.3
Gorkiewicz, G.4
Meyer, C.5
Rozman, J.6
Heldmaier, G.7
Maier, R.8
Theussl, C.9
Eder, S.10
-
58
-
-
84862908245
-
Dissociation of inositol-requiring enzyme (IRE1α)-mediated c-Jun N-terminal kinase activation from hepatic insulin resistance in conditional X-box-binding protein-1 (XBP1) knock-out mice
-
M.J. Jurczak, A.H. Lee, F.R. Jornayvaz, H.Y. Lee, A.L. Birkenfeld, B.A. Guigni, M. Kahn, V.T. Samuel, L.H. Glimcher, and G.I. Shulman Dissociation of inositol-requiring enzyme (IRE1α)-mediated c-Jun N-terminal kinase activation from hepatic insulin resistance in conditional X-box-binding protein-1 (XBP1) knock-out mice J. Biol. Chem. 287 2012 2558 2567
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 2558-2567
-
-
Jurczak, M.J.1
Lee, A.H.2
Jornayvaz, F.R.3
Lee, H.Y.4
Birkenfeld, A.L.5
Guigni, B.A.6
Kahn, M.7
Samuel, V.T.8
Glimcher, L.H.9
Shulman, G.I.10
-
59
-
-
0038025371
-
Mitochondrial dysfunction in the elderly: Possible role in insulin resistance
-
K.F. Petersen, D. Befroy, S. Dufour, J. Dziura, C. Ariyan, D.L. Rothman, L. DiPietro, G.W. Cline, and G.I. Shulman Mitochondrial dysfunction in the elderly: possible role in insulin resistance Science 300 2003 1140 1142
-
(2003)
Science
, vol.300
, pp. 1140-1142
-
-
Petersen, K.F.1
Befroy, D.2
Dufour, S.3
Dziura, J.4
Ariyan, C.5
Rothman, D.L.6
Dipietro, L.7
Cline, G.W.8
Shulman, G.I.9
|