Two protein kinase C isoforms, δ and ε, regulate energy homeostasis in mitochondria by transmitting opposing signals to the pyruvate dehydrogenase complex

FASEB Journal

Volumn 26, Issue 8, 2012, Pages 3537-3549

  Gong, Jianli ^a,d   Hoyos, Beatrice ^a   Acin Perez, Rebeca ^b   Vinogradov, Valerie ^a   Shabrova, Elena ^a   Zhao, Feng ^a   Leitges, Michael ^c   Fischman, Donald ^b   Manfredi, Giovanni ^b   Hammerling, Ulrich ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

^c UNIVERSITY OF OSLO   (Norway)

^d Columbia University ^*  (United States)

Author keywords

Mitochondrial energy metabolism; Redox biology; Respiration; Retinoids; Signal transduction; Vitamin A physiology

Indexed keywords

CYTOCHROME C; FENRETINIDE; ISOENZYME; PROTEIN KINASE C DELTA; PROTEIN KINASE C EPSILON; PYRUVATE DEHYDROGENASE COMPLEX; RETINOL;

ANIMAL TISSUE; ARTICLE; CITRIC ACID CYCLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; ENERGY METABOLISM; ENERGY YIELD; ENZYME ACTIVATION; ENZYME INHIBITION; GENE REPRESSION; HOMEOSTASIS; MITOCHONDRIAL ENERGY TRANSFER; MITOCHONDRION; MOUSE; NONHUMAN; OBESITY; OXIDATION REDUCTION STATE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TUMOR CELL;

ANIMALS; CELL LINE; CITRIC ACID CYCLE; ENERGY METABOLISM; ENZYME ACTIVATION; FENRETINIDE; HOMEOSTASIS; MICE; MITOCHONDRIA, LIVER; OXIDATIVE PHOSPHORYLATION; PHOSPHORYLATION; PROTEIN KINASE C-DELTA; PROTEIN KINASE C-EPSILON; PYRUVATE DEHYDROGENASE COMPLEX; SIGNAL TRANSDUCTION; VITAMIN A; ZINC FINGERS;

ANIMALIA;

EID: 84864754109     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.11-197376     Document Type: Article

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