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Volumn 15, Issue 6, 2016, Pages 513-528

Cannabinoids and autoimmune diseases: A systematic review

Author keywords

Autoimmune diseases; Cannabinoids; Endocannabinoid system; Fibromyalgia; Immunosuppression; Inflammatory bowel disease; Multiple sclerosis; Neuropathic pain; Rheumatoid arthritis; Scleroderma; Tetrahydrocannabinol (THC); Type 1 Diabetes

Indexed keywords

CANNABINOID 1 RECEPTOR; CANNABINOID 2 RECEPTOR; CANNABINOID DERIVATIVE; CANNABINOID RECEPTOR AGONIST; ENDOCANNABINOID; NEUROTRANSMITTER; CANNABINOID;

EID: 84963775522     PISSN: 15689972     EISSN: 18730183     Source Type: Journal    
DOI: 10.1016/j.autrev.2016.02.008     Document Type: Review
Times cited : (117)

References (270)
  • 1
    • 84884474728 scopus 로고    scopus 로고
    • School of Medical Sciences Institute of Medical Sciences, University of Aberdeen, HEP
    • Pertwee R.G. Pharmacological actions of cannabinoids 2005, 168:1-51. School of Medical Sciences Institute of Medical Sciences, University of Aberdeen, HEP.
    • (2005) Pharmacological actions of cannabinoids , vol.168 , pp. 1-51
    • Pertwee, R.G.1
  • 2
    • 18444376760 scopus 로고    scopus 로고
    • International Union of Pharmacology. XXVII. Classification of cannabinoid receptors
    • Howlett C., Barth F., Bonner T.I., Cabral G., Casellas P., Devane W.A., et al. International Union of Pharmacology. XXVII. Classification of cannabinoid receptors. Pharmacol Rev 2002, 54:161-202.
    • (2002) Pharmacol Rev , vol.54 , pp. 161-202
    • Howlett, C.1    Barth, F.2    Bonner, T.I.3    Cabral, G.4    Casellas, P.5    Devane, W.A.6
  • 3
    • 30444457225 scopus 로고    scopus 로고
    • Cannabinoid pharmacology: the first 66 years
    • Pertwee R.G. Cannabinoid pharmacology: the first 66 years. Br J Pharmacol 2006, 147(S1):S163-S171.
    • (2006) Br J Pharmacol , vol.147 , pp. S163-S171
    • Pertwee, R.G.1
  • 4
    • 55849117700 scopus 로고    scopus 로고
    • CB1 receptor antagonism: biological basis for metabolic effects
    • Di Marzo V. CB1 receptor antagonism: biological basis for metabolic effects. Drug Discov Today 2008, 1-16.
    • (2008) Drug Discov Today
    • Di Marzo, V.1
  • 5
    • 32444440208 scopus 로고    scopus 로고
    • The emerging role of the endocannabinoid system in endocrine regulation and energy balance
    • Feb
    • Pagotto U., Marsicano G., Cota D., Lutz B., Pasquali R. The emerging role of the endocannabinoid system in endocrine regulation and energy balance. Endocr Rev Feb 2006, 27(1):73-100.
    • (2006) Endocr Rev , vol.27 , Issue.1 , pp. 73-100
    • Pagotto, U.1    Marsicano, G.2    Cota, D.3    Lutz, B.4    Pasquali, R.5
  • 6
    • 33645796477 scopus 로고    scopus 로고
    • Cannabinoid receptor signaling
    • Howlett A.C. Cannabinoid receptor signaling. Handb Exp Pharmacol 2005, 53-79.
    • (2005) Handb Exp Pharmacol , pp. 53-79
    • Howlett, A.C.1
  • 7
    • 0031834745 scopus 로고    scopus 로고
    • 'Endocannabinoids'and other fatty acid derivatives with cannabimimetic properties: biochemistry and possible physiopathological relevance
    • Di Marzo V. 'Endocannabinoids'and other fatty acid derivatives with cannabimimetic properties: biochemistry and possible physiopathological relevance. Biochim Biophys Acta 1998, 1392:153-175.
    • (1998) Biochim Biophys Acta , vol.1392 , pp. 153-175
    • Di Marzo, V.1
  • 8
    • 0034978249 scopus 로고    scopus 로고
    • Mechanisms of endocannabinoid inactivation: biochemistry and pharmacology
    • Giuffrida A., Beltramo M., Piomelli D. Mechanisms of endocannabinoid inactivation: biochemistry and pharmacology. J Pharmacol Exp Ther 2001, 298:7-14.
    • (2001) J Pharmacol Exp Ther , vol.298 , pp. 7-14
    • Giuffrida, A.1    Beltramo, M.2    Piomelli, D.3
  • 9
    • 0037207088 scopus 로고    scopus 로고
    • A role for monoglyceride lipase in 2-arachidonoylglycerol inactivation
    • Dinh T.P., Freund T.F., Piomelli D. A role for monoglyceride lipase in 2-arachidonoylglycerol inactivation. Chem Phys Lipids 2002, 121:149-158.
    • (2002) Chem Phys Lipids , vol.121 , pp. 149-158
    • Dinh, T.P.1    Freund, T.F.2    Piomelli, D.3
  • 10
    • 0030611978 scopus 로고    scopus 로고
    • Pharmacology of cannabinoid CB1 and CB2 receptors
    • Pertwee R.G. Pharmacology of cannabinoid CB1 and CB2 receptors. Pharmacol Ther 1997, 74:129-180.
    • (1997) Pharmacol Ther , vol.74 , pp. 129-180
    • Pertwee, R.G.1
  • 11
    • 0034004184 scopus 로고    scopus 로고
    • O-1057, a potent water-soluble cannabinoid receptor agonist with antinociceptive properties
    • Pertwee R.G., Gibson T.M., Stevenson L.A., Ross R.A., Banner W.K., Saha B., et al. O-1057, a potent water-soluble cannabinoid receptor agonist with antinociceptive properties. Br J Pharmacol 2000, 129:1577-1584.
    • (2000) Br J Pharmacol , vol.129 , pp. 1577-1584
    • Pertwee, R.G.1    Gibson, T.M.2    Stevenson, L.A.3    Ross, R.A.4    Banner, W.K.5    Saha, B.6
  • 12
    • 0038692066 scopus 로고    scopus 로고
    • Cannabis and the brain
    • Iversen L. Cannabis and the brain. Brain 2003, 126:1252-1270.
    • (2003) Brain , vol.126 , pp. 1252-1270
    • Iversen, L.1
  • 13
    • 0036488182 scopus 로고    scopus 로고
    • Neuroprotective properties of cannabinoids against oxidative stress: role of the cannabinoid receptor CB1
    • Marsicano G., Moosmann B., Hermann H., Lutz B., Behl C. Neuroprotective properties of cannabinoids against oxidative stress: role of the cannabinoid receptor CB1. J Neurochem 2002, 80:448-456.
    • (2002) J Neurochem , vol.80 , pp. 448-456
    • Marsicano, G.1    Moosmann, B.2    Hermann, H.3    Lutz, B.4    Behl, C.5
  • 14
    • 0027078685 scopus 로고
    • Isolation and structure of a brain constituent that binds to the cannabinoid receptor
    • Devane W.A., Hanus L., Breuer A., Pertwee R.G., Stevenson L.A., Griffin G., et al. Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science 1992, 258:1946-1949.
    • (1992) Science , vol.258 , pp. 1946-1949
    • Devane, W.A.1    Hanus, L.2    Breuer, A.3    Pertwee, R.G.4    Stevenson, L.A.5    Griffin, G.6
  • 15
    • 33947128224 scopus 로고    scopus 로고
    • Endocannabinoids and the regulation of their levels in health and disease
    • Di Marzo V., Petrosino S. Endocannabinoids and the regulation of their levels in health and disease. Curr Opin Lipidol 2007, 18:129-140.
    • (2007) Curr Opin Lipidol , vol.18 , pp. 129-140
    • Di Marzo, V.1    Petrosino, S.2
  • 16
    • 0004906771 scopus 로고    scopus 로고
    • Direct activation of capsaicin receptors by products of lipoxygenases: endogenous capsaicin-like substances
    • Hwang S.W., Cho H., Kwak J., Lee S.Y., Kang C.J., Jung J., et al. Direct activation of capsaicin receptors by products of lipoxygenases: endogenous capsaicin-like substances. Proc Natl Acad Sci U S A 2000, 97:6155-6160.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 6155-6160
    • Hwang, S.W.1    Cho, H.2    Kwak, J.3    Lee, S.Y.4    Kang, C.J.5    Jung, J.6
  • 17
    • 0038007619 scopus 로고    scopus 로고
    • Anandamide regulates neuropeptide release from capsaicin-sensitive primary sensory neurons by activating both the cannabinoid 1 receptor and the vanilloid receptor 1 in vitro
    • Ahluwalia J., Urban L., Bevan S., Nagy I. Anandamide regulates neuropeptide release from capsaicin-sensitive primary sensory neurons by activating both the cannabinoid 1 receptor and the vanilloid receptor 1 in vitro. Eur J Neurosci 2003, 17:2611-2618.
    • (2003) Eur J Neurosci , vol.17 , pp. 2611-2618
    • Ahluwalia, J.1    Urban, L.2    Bevan, S.3    Nagy, I.4
  • 18
    • 2342626531 scopus 로고    scopus 로고
    • Modulation of trigeminal sensory neuron activity by the dual cannabinoidvanilloid agonists anandamide, N-arachidonoyl-dopamine and arachidonyl-2-chloroethylamide
    • Price T.J., Patwardhan A., Akopian A.N., Hargreaves K.M., Flores C.M. Modulation of trigeminal sensory neuron activity by the dual cannabinoidvanilloid agonists anandamide, N-arachidonoyl-dopamine and arachidonyl-2-chloroethylamide. Br J Pharmacol 2004, 141:1118-1130.
    • (2004) Br J Pharmacol , vol.141 , pp. 1118-1130
    • Price, T.J.1    Patwardhan, A.2    Akopian, A.N.3    Hargreaves, K.M.4    Flores, C.M.5
  • 19
    • 0033614984 scopus 로고    scopus 로고
    • Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide
    • Zygmunt P.M., Petersson J., Andersson D.A., Chuang H., Sshrgyerd M., Di Marzo V., et al. Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide. Nature 1999, 400:452-457.
    • (1999) Nature , vol.400 , pp. 452-457
    • Zygmunt, P.M.1    Petersson, J.2    Andersson, D.A.3    Chuang, H.4    Sshrgyerd, M.5    Di Marzo, V.6
  • 20
    • 0035866048 scopus 로고    scopus 로고
    • Anandamide excites central terminals of dorsal root ganglion neurons via vanilloid receptor-1 activation
    • Tognetto M., Amadesi S., Harrison S., Creminon S., Trevisani M., Carreras M., et al. Anandamide excites central terminals of dorsal root ganglion neurons via vanilloid receptor-1 activation. J Neurosci 2001, 21:1104-1109.
    • (2001) J Neurosci , vol.21 , pp. 1104-1109
    • Tognetto, M.1    Amadesi, S.2    Harrison, S.3    Creminon, S.4    Trevisani, M.5    Carreras, M.6
  • 21
    • 0037162482 scopus 로고    scopus 로고
    • Bradykinin-12-lipoxygenase-VR1 signaling pathway for inflammatory hyperalgesia
    • Shin J., Cho H., Hwang S.W., Jung J., Shin C.Y., Lee S.Y., et al. Bradykinin-12-lipoxygenase-VR1 signaling pathway for inflammatory hyperalgesia. Proc Natl Acad Sci U S A 2002, 99:10150-10155.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 10150-10155
    • Shin, J.1    Cho, H.2    Hwang, S.W.3    Jung, J.4    Shin, C.Y.5    Lee, S.Y.6
  • 22
    • 1842611872 scopus 로고    scopus 로고
    • Characterisation of the vasorelaxant properties of the novel endocannabinoid N-arachidonoyl-dopamine (NADA)
    • O'Sullivan S.E., Kendall D.A., Randall M.D. Characterisation of the vasorelaxant properties of the novel endocannabinoid N-arachidonoyl-dopamine (NADA). Br J Pharmacol 2004, 141:803-812.
    • (2004) Br J Pharmacol , vol.141 , pp. 803-812
    • O'Sullivan, S.E.1    Kendall, D.A.2    Randall, M.D.3
  • 23
    • 18844400058 scopus 로고    scopus 로고
    • Cannabinoid-based drugs as anti-inflammatory therapeutics
    • Klein T.W. Cannabinoid-based drugs as anti-inflammatory therapeutics. Nat Rev Immunol 2005, 5:400-411.
    • (2005) Nat Rev Immunol , vol.5 , pp. 400-411
    • Klein, T.W.1
  • 24
    • 84862575210 scopus 로고    scopus 로고
    • Adenosine A2A receptor activation stimulates collagen production in sclerodermic dermal fibroblasts either directly and through a cross-talk with the cannabinoid system
    • Lazzerini P.E., Natale M., Gianchecchi E., et al. Adenosine A2A receptor activation stimulates collagen production in sclerodermic dermal fibroblasts either directly and through a cross-talk with the cannabinoid system. J Mol Med (Berl) 2012, 90:331-342.
    • (2012) J Mol Med (Berl) , vol.90 , pp. 331-342
    • Lazzerini, P.E.1    Natale, M.2    Gianchecchi, E.3
  • 25
    • 21044460152 scopus 로고    scopus 로고
    • Inverse agonism at cannabinoid receptors
    • Elsevier, Amsterdam, A.P. IJzerman (Ed.)
    • Pertwee R.G. Inverse agonism at cannabinoid receptors. Inverse Agonism 2003, 75-86. Elsevier, Amsterdam. A.P. IJzerman (Ed.).
    • (2003) Inverse Agonism , pp. 75-86
    • Pertwee, R.G.1
  • 26
    • 2342587090 scopus 로고    scopus 로고
    • Novel pharmacological targets for cannabinoids
    • Pertwee R.G. Novel pharmacological targets for cannabinoids. Curr Neuropharmacol 2004, 2:9-29.
    • (2004) Curr Neuropharmacol , vol.2 , pp. 9-29
    • Pertwee, R.G.1
  • 27
    • 0032586854 scopus 로고    scopus 로고
    • Modification of 5-HT2 receptor mediated behaviour in the rat by oleamide and the role of cannabinoid receptors
    • Cheer J.F., Cadogan A.-K., Marsden C.A., Fone K.C.F., Kendall D.A. Modification of 5-HT2 receptor mediated behaviour in the rat by oleamide and the role of cannabinoid receptors. Neuropharmacology 1999, 38:533-541.
    • (1999) Neuropharmacology , vol.38 , pp. 533-541
    • Cheer, J.F.1    Cadogan, A.-K.2    Marsden, C.A.3    Fone, K.C.F.4    Kendall, D.A.5
  • 28
    • 0036850272 scopus 로고    scopus 로고
    • Direct inhibition by cannabinoids of human 5-HT3A receptors: probable involvement of an allosteric modulatory site
    • Barann M., Molderings G., Brss M., Btsnisch H., Urban B.W., Gtsthert M. Direct inhibition by cannabinoids of human 5-HT3A receptors: probable involvement of an allosteric modulatory site. Br J Pharmacol 2002, 137:589-596.
    • (2002) Br J Pharmacol , vol.137 , pp. 589-596
    • Barann, M.1    Molderings, G.2    Brss, M.3    Btsnisch, H.4    Urban, B.W.5    Gtsthert, M.6
  • 29
    • 0028954055 scopus 로고
    • Cannabinoid agonists inhibit the activation of 5-HT3 receptors in rat nodose ganglion neurons
    • Fan P. Cannabinoid agonists inhibit the activation of 5-HT3 receptors in rat nodose ganglion neurons. J Neurophysiol 1995, 73:907-910.
    • (1995) J Neurophysiol , vol.73 , pp. 907-910
    • Fan, P.1
  • 30
    • 0037351831 scopus 로고    scopus 로고
    • Cannabinoid receptor-independent inhibition by cannabinoid agonists of the peripheral 5-HT3 receptor-mediated von Bezold- Jarisch reflex
    • Godlewski G., Gtsthert M., Malinowska B. Cannabinoid receptor-independent inhibition by cannabinoid agonists of the peripheral 5-HT3 receptor-mediated von Bezold- Jarisch reflex. Br J Pharmacol 2003, 138:767-774.
    • (2003) Br J Pharmacol , vol.138 , pp. 767-774
    • Godlewski, G.1    Gtsthert, M.2    Malinowska, B.3
  • 31
    • 0036887679 scopus 로고    scopus 로고
    • Endogenous cannabinoid, anandamide, acts as a noncompetitive inhibitor on 5-HT3 receptor-mediated responses in Xenopus oocytes
    • Oz M., Zhang L., Morales M. Endogenous cannabinoid, anandamide, acts as a noncompetitive inhibitor on 5-HT3 receptor-mediated responses in Xenopus oocytes. Synapse 2002, 46:150-156.
    • (2002) Synapse , vol.46 , pp. 150-156
    • Oz, M.1    Zhang, L.2    Morales, M.3
  • 32
    • 0035812920 scopus 로고    scopus 로고
    • Interaction of anandamide with the M1 and M4 muscarinic acetylcholine receptors
    • Christopoulos A., Wilson K. Interaction of anandamide with the M1 and M4 muscarinic acetylcholine receptors. Brain Res 2001, 915:70-78.
    • (2001) Brain Res , vol.915 , pp. 70-78
    • Christopoulos, A.1    Wilson, K.2
  • 34
    • 0032837241 scopus 로고    scopus 로고
    • Anandamide inhibition of recombinant AMPA receptor subunits in Xenopus oocytes is increased by forskolin and 8-bromo-cyclic AMP
    • Akinshola B.E., Taylor R.E., Ogunseitan A.B., Onaivi E.S. Anandamide inhibition of recombinant AMPA receptor subunits in Xenopus oocytes is increased by forskolin and 8-bromo-cyclic AMP. Naunyn Schmiedebergs Arch Pharmacol 1999, 360:242-248.
    • (1999) Naunyn Schmiedebergs Arch Pharmacol , vol.360 , pp. 242-248
    • Akinshola, B.E.1    Taylor, R.E.2    Ogunseitan, A.B.3    Onaivi, E.S.4
  • 35
    • 67349203919 scopus 로고    scopus 로고
    • Review role of endocannabinoids and endovanilloids in Ca2+ signaling
    • De Petrocellis L., Di Marzo V. Review role of endocannabinoids and endovanilloids in Ca2+ signaling. Cell Calcium 2009, 45:611-624.
    • (2009) Cell Calcium , vol.45 , pp. 611-624
    • De Petrocellis, L.1    Di Marzo, V.2
  • 36
    • 3242756915 scopus 로고    scopus 로고
    • Pharmacology of cannabinoids
    • Nos.1/2, Feb-Apr
    • Grotenhermen F. Pharmacology of cannabinoids. Neuroendocrinol Lett 2004, 25(1/2):14-23. Nos.1/2, Feb-Apr.
    • (2004) Neuroendocrinol Lett , vol.25 , Issue.1-2 , pp. 14-23
    • Grotenhermen, F.1
  • 37
    • 0022509199 scopus 로고
    • Cannabinoid pharmacology
    • Dewey W.L. Cannabinoid pharmacology. Pharmacol Rev 1986, 38:151-178.
    • (1986) Pharmacol Rev , vol.38 , pp. 151-178
    • Dewey, W.L.1
  • 38
    • 0001823980 scopus 로고
    • In vivo interactions between psychotropic cannabinoids and other drugs involving central and peripheral neurochemical mediators
    • CRC Press
    • Pertwee R. In vivo interactions between psychotropic cannabinoids and other drugs involving central and peripheral neurochemical mediators. Marijuana/cannabinoids: neurobiology and neurophysiology 1992, 165-218. CRC Press.
    • (1992) Marijuana/cannabinoids: neurobiology and neurophysiology , pp. 165-218
    • Pertwee, R.1
  • 41
    • 0028294964 scopus 로고
    • Effects of cannabinoids (marijuana) on taste intensity and hedonic ratings and salivary flow of adults
    • Mattes R.D., Shaw L.M., Engelman K. Effects of cannabinoids (marijuana) on taste intensity and hedonic ratings and salivary flow of adults. Chem Senses 1994, 19:125-140.
    • (1994) Chem Senses , vol.19 , pp. 125-140
    • Mattes, R.D.1    Shaw, L.M.2    Engelman, K.3
  • 42
    • 0028954055 scopus 로고
    • Cannabinoid agonists inhibit the activation of 5-HT3 receptors in rat nodose ganglion neurons
    • Fan P. Cannabinoid agonists inhibit the activation of 5-HT3 receptors in rat nodose ganglion neurons. J Neurophysiol 1995, 73:907-910.
    • (1995) J Neurophysiol , vol.73 , pp. 907-910
    • Fan, P.1
  • 45
    • 0036798247 scopus 로고    scopus 로고
    • The therapeutic potential of the cannabinoids in neuroprotection
    • Grundy R.I. The therapeutic potential of the cannabinoids in neuroprotection. Expert Opin Investig Drugs 2002, 11:1365-1374.
    • (2002) Expert Opin Investig Drugs , vol.11 , pp. 1365-1374
    • Grundy, R.I.1
  • 46
    • 85071752428 scopus 로고    scopus 로고
    • Cannabinoids as neuroprotectants against ischemia. Cannabis and cannabinoids
    • Haworth Press
    • A.Hampson Cannabinoids as neuroprotectants against ischemia. Cannabis and cannabinoids. Pharmacology, toxicology, and therapeutic potential 2002, 101-110. Haworth Press.
    • (2002) Pharmacology, toxicology, and therapeutic potential , pp. 101-110
    • Hampson, A.1
  • 48
    • 0002864824 scopus 로고    scopus 로고
    • The psychologic and physiologic effects of active cannabinoids
    • Humana Press
    • Perez-Reyes M. The psychologic and physiologic effects of active cannabinoids. Marihuana and medicine 1999, 245-252. Humana Press.
    • (1999) Marihuana and medicine , pp. 245-252
    • Perez-Reyes, M.1
  • 49
    • 0017652307 scopus 로고
    • Shortterm effects of smoked marihuana on left ventricular function in man
    • Tashkin D.P., Levisman J.A., Abbasi A.S., Shapiro B.J., Ellis N.M. Shortterm effects of smoked marihuana on left ventricular function in man. Chest 1977, 72:20-26.
    • (1977) Chest , vol.72 , pp. 20-26
    • Tashkin, D.P.1    Levisman, J.A.2    Abbasi, A.S.3    Shapiro, B.J.4    Ellis, N.M.5
  • 50
    • 0016769009 scopus 로고
    • Cardiovascular effects of prolonged delta-9-tetrahydrocannabinol ingestion
    • Benowitz N.L., Jones R.T. Cardiovascular effects of prolonged delta-9-tetrahydrocannabinol ingestion. Clin Pharmacol Ther 1975, 18:287-297.
    • (1975) Clin Pharmacol Ther , vol.18 , pp. 287-297
    • Benowitz, N.L.1    Jones, R.T.2
  • 51
    • 0022472739 scopus 로고
    • Health aspects of cannabis
    • Hollister L.E. Health aspects of cannabis. Pharmacol Rev 1986, 38:1-20.
    • (1986) Pharmacol Rev , vol.38 , pp. 1-20
    • Hollister, L.E.1
  • 52
    • 0031773354 scopus 로고    scopus 로고
    • Cardiovascular actions of cannabinoids and their generation during shock
    • Wagner J.A., Varga K., Kunos G. Cardiovascular actions of cannabinoids and their generation during shock. J Mol Med 1998, 76:824-836.
    • (1998) J Mol Med , vol.76 , pp. 824-836
    • Wagner, J.A.1    Varga, K.2    Kunos, G.3
  • 53
    • 0035816432 scopus 로고    scopus 로고
    • Hemodynamic effects of cannabinoids: coronary and cerebral vasodilation mediated by cannabinoid CB1 receptors
    • Wagner J.A., Jarai Z., Batkai S., Kunos G. Hemodynamic effects of cannabinoids: coronary and cerebral vasodilation mediated by cannabinoid CB1 receptors. Eur J Pharmacol 2001, 423:203-210.
    • (2001) Eur J Pharmacol , vol.423 , pp. 203-210
    • Wagner, J.A.1    Jarai, Z.2    Batkai, S.3    Kunos, G.4
  • 54
    • 0030925426 scopus 로고    scopus 로고
    • Cannabinoid induced hypotension and bradycardia in rats is mediated by CB1-like cannabinoid receptors
    • Lake K.D., Compton D.R., Varga K., Martin B.R., Kunos G. Cannabinoid induced hypotension and bradycardia in rats is mediated by CB1-like cannabinoid receptors. J Pharmacol Exp Ther 1997, 281:1030-1037.
    • (1997) J Pharmacol Exp Ther , vol.281 , pp. 1030-1037
    • Lake, K.D.1    Compton, D.R.2    Varga, K.3    Martin, B.R.4    Kunos, G.5
  • 55
    • 0035848818 scopus 로고    scopus 로고
    • Leptin-regulated endocannabinoids are involved in maintaining food intake
    • Di Marzo V., Goparaju S.K., Wang L., Liu J., Batkai S., Jarai Z., et al. Leptin-regulated endocannabinoids are involved in maintaining food intake. Nature 2001, 410:822-825.
    • (2001) Nature , vol.410 , pp. 822-825
    • Di Marzo, V.1    Goparaju, S.K.2    Wang, L.3    Liu, J.4    Batkai, S.5    Jarai, Z.6
  • 57
    • 0024370916 scopus 로고
    • Psychoactive cannabinoids reduce gastrointestinal propulsion and motility in rodents
    • Shook J.E., Burks T.F. Psychoactive cannabinoids reduce gastrointestinal propulsion and motility in rodents. J Pharmacol Exp Ther 1989, 249:444-449.
    • (1989) J Pharmacol Exp Ther , vol.249 , pp. 444-449
    • Shook, J.E.1    Burks, T.F.2
  • 58
    • 0032940913 scopus 로고    scopus 로고
    • Delta-9-tetrahydrocannabinol delays the gastric emptying of solid food in humans: a double-blind, randomized study
    • McCallum R.W., Soykan I., Sridhar K.R., Ricci D.A., Lange R.C., Plankey M.W. Delta-9-tetrahydrocannabinol delays the gastric emptying of solid food in humans: a double-blind, randomized study. Aliment Pharmacol Ther 1999, 13:77-80.
    • (1999) Aliment Pharmacol Ther , vol.13 , pp. 77-80
    • McCallum, R.W.1    Soykan, I.2    Sridhar, K.R.3    Ricci, D.A.4    Lange, R.C.5    Plankey, M.W.6
  • 59
    • 85071764804 scopus 로고    scopus 로고
    • Hormonal system and reproduction. Cannabis and cannabinoids
    • Haworth Press
    • Murphy L. Hormonal system and reproduction. Cannabis and cannabinoids. Pharmacology, toxicology, and therapeutic potential 2002, 289-298. Haworth Press.
    • (2002) Pharmacology, toxicology, and therapeutic potential , pp. 289-298
    • Murphy, L.1
  • 60
    • 85071743204 scopus 로고    scopus 로고
    • Glaucoma and cannabinoids. Cannabis and cannabinoids
    • Haworth Press, (101)
    • Pate D. Glaucoma and cannabinoids. Cannabis and cannabinoids. Pharmacology, toxicology, and therapeutic potential 2002, 215-224. Haworth Press, (101).
    • (2002) Pharmacology, toxicology, and therapeutic potential , pp. 215-224
    • Pate, D.1
  • 61
    • 0037414741 scopus 로고    scopus 로고
    • Topically administered CB(2)-receptor agonist, JWH-133, does not decrease intraocular pressure (IOP) in normotensive rabbits
    • Laine K., Jarvinen K., Jarvinen T. Topically administered CB(2)-receptor agonist, JWH-133, does not decrease intraocular pressure (IOP) in normotensive rabbits. Life Sci 2003, 72:837-842.
    • (2003) Life Sci , vol.72 , pp. 837-842
    • Laine, K.1    Jarvinen, K.2    Jarvinen, T.3
  • 62
    • 67649450077 scopus 로고    scopus 로고
    • Acute administration of the cannabinoid CB1 antagonist rimonabant impairs positive affective memory in healthy volunteers
    • Jul
    • Horder J., Cowen P.J., Di Simplicio M., Browning M., Harmer C.J. Acute administration of the cannabinoid CB1 antagonist rimonabant impairs positive affective memory in healthy volunteers. Psychopharmacology Jul 2009, 205(1):85-91.
    • (2009) Psychopharmacology , vol.205 , Issue.1 , pp. 85-91
    • Horder, J.1    Cowen, P.J.2    Di Simplicio, M.3    Browning, M.4    Harmer, C.J.5
  • 63
    • 0032586373 scopus 로고    scopus 로고
    • SR 141716 A, a cannabinoid receptor antagonist, reverses the behavioural effects of anandamide-treated rats
    • Costa B., Vailati S., Colleoni M. SR 141716 A, a cannabinoid receptor antagonist, reverses the behavioural effects of anandamide-treated rats. Behav Pharmacol 1999, 10:327-331.
    • (1999) Behav Pharmacol , vol.10 , pp. 327-331
    • Costa, B.1    Vailati, S.2    Colleoni, M.3
  • 64
    • 0030738512 scopus 로고    scopus 로고
    • Selective inhibition of sucrose and ethanol intake by SR 141716, an antagonist of central cannabinoid (CB1) receptors
    • Arnone M., Maruani J., Chaperon F., Thiebot M.H., Poncelet M., Soubrie P., et al. Selective inhibition of sucrose and ethanol intake by SR 141716, an antagonist of central cannabinoid (CB1) receptors. Psychopharmacol 1997, 132:104-106.
    • (1997) Psychopharmacol , vol.132 , pp. 104-106
    • Arnone, M.1    Maruani, J.2    Chaperon, F.3    Thiebot, M.H.4    Poncelet, M.5    Soubrie, P.6
  • 65
    • 0032541111 scopus 로고    scopus 로고
    • Appetite suppression and weight loss after the cannabinoid antagonist SR 141716
    • Colombo G., Agabio R., Diaz G., Lobina C., Reali R., Gessa G.L. Appetite suppression and weight loss after the cannabinoid antagonist SR 141716. Life Sci 1998, 63:113-117.
    • (1998) Life Sci , vol.63 , pp. 113-117
    • Colombo, G.1    Agabio, R.2    Diaz, G.3    Lobina, C.4    Reali, R.5    Gessa, G.L.6
  • 66
    • 0031902759 scopus 로고    scopus 로고
    • SR 141716, a CB1 cannabinoid receptor antagonist, selectively reduces sweet food intake in marmoset
    • Simiand J., Keane M., Keane P.-E., Soubrie P. SR 141716, a CB1 cannabinoid receptor antagonist, selectively reduces sweet food intake in marmoset. Behav Pharmacol 1998, 9:179-181.
    • (1998) Behav Pharmacol , vol.9 , pp. 179-181
    • Simiand, J.1    Keane, M.2    Keane, P.-E.3    Soubrie, P.4
  • 67
    • 0036669295 scopus 로고    scopus 로고
    • Tetrahydrocannabinol and endocannabinoids in feeding and appetite
    • Berry E.M., Mechoulam R. Tetrahydrocannabinol and endocannabinoids in feeding and appetite. Pharmacol Ther 2002, 95:185-190.
    • (2002) Pharmacol Ther , vol.95 , pp. 185-190
    • Berry, E.M.1    Mechoulam, R.2
  • 70
    • 0033661798 scopus 로고    scopus 로고
    • Cannabinoid receptors and the regulation of immune response
    • Berdyshev E.V. Cannabinoid receptors and the regulation of immune response. Chem Phys Lipids 2000, 108:169-190.
    • (2000) Chem Phys Lipids , vol.108 , pp. 169-190
    • Berdyshev, E.V.1
  • 72
    • 0031732250 scopus 로고    scopus 로고
    • Anandamide synthesis is induced by arachidonate mobilizing agonists in cells of the immune system
    • Pestonjamasp V.K., Burstein S.H. Anandamide synthesis is induced by arachidonate mobilizing agonists in cells of the immune system. Biochim Biophys Acta 1998, 1394:249-260.
    • (1998) Biochim Biophys Acta , vol.1394 , pp. 249-260
    • Pestonjamasp, V.K.1    Burstein, S.H.2
  • 73
    • 0031031557 scopus 로고    scopus 로고
    • Biosynthesis, uptake, and degradation of anandamide and palmitoylethanolamide in leukocytes
    • Bisogno T., Maurelli S., Melck D., De Petrocellis L., Di Marzo V. Biosynthesis, uptake, and degradation of anandamide and palmitoylethanolamide in leukocytes. J Biol Chem 1997, 272:3315-3323.
    • (1997) J Biol Chem , vol.272 , pp. 3315-3323
    • Bisogno, T.1    Maurelli, S.2    Melck, D.3    De Petrocellis, L.4    Di Marzo, V.5
  • 74
    • 0035816415 scopus 로고    scopus 로고
    • Differential expression of cannabinoid cb(2) receptor mrna in mouse immune cell subpopulations and following b cell stimulation
    • Lee S.F., Newton C., Widen R., Friedman H., Klein T.W. Differential expression of cannabinoid cb(2) receptor mrna in mouse immune cell subpopulations and following b cell stimulation. Eur J Pharmacol 2001, 423(2-3):235-241.
    • (2001) Eur J Pharmacol , vol.423 , Issue.2-3 , pp. 235-241
    • Lee, S.F.1    Newton, C.2    Widen, R.3    Friedman, H.4    Klein, T.W.5
  • 75
    • 33745506297 scopus 로고    scopus 로고
    • Endocannabinoids and the gastrointestinal tract
    • Massa F., Monory K. Endocannabinoids and the gastrointestinal tract. J Endocrinol Invest 2006, 29:47-57.
    • (2006) J Endocrinol Invest , vol.29 , pp. 47-57
    • Massa, F.1    Monory, K.2
  • 76
    • 34250209535 scopus 로고    scopus 로고
    • Attenuation of allergic contact dermatitis through the endocannabinoid system
    • Karsak M., Gaffal E., Date R., Wang-Eckhardt L., Rehnelt J., Petrosino S., et al. Attenuation of allergic contact dermatitis through the endocannabinoid system. Science 2007, 316:1494-1497.
    • (2007) Science , vol.316 , pp. 1494-1497
    • Karsak, M.1    Gaffal, E.2    Date, R.3    Wang-Eckhardt, L.4    Rehnelt, J.5    Petrosino, S.6
  • 77
    • 28544450602 scopus 로고    scopus 로고
    • The endocannabinoid system in the physiology and pathophysiology of the gastrointestinal tract
    • Massa F., Storr M., Lutz B. The endocannabinoid system in the physiology and pathophysiology of the gastrointestinal tract. J Mol Med 2005, 83:944-954.
    • (2005) J Mol Med , vol.83 , pp. 944-954
    • Massa, F.1    Storr, M.2    Lutz, B.3
  • 78
    • 0034766553 scopus 로고    scopus 로고
    • Pharmacological actions and therapeutic uses of cannabis and cannabinoids
    • Kumar R.N., Chambers W.A., Pertwee R.G. Pharmacological actions and therapeutic uses of cannabis and cannabinoids. Anaesthesia 2001, 56:1059-1068.
    • (2001) Anaesthesia , vol.56 , pp. 1059-1068
    • Kumar, R.N.1    Chambers, W.A.2    Pertwee, R.G.3
  • 80
    • 0033661798 scopus 로고    scopus 로고
    • Cannabinoid receptors and the regulation of immune response
    • Berdyshev E.V. Cannabinoid receptors and the regulation of immune response. Chem Phys Lipids 2000, 108:169-190.
    • (2000) Chem Phys Lipids , vol.108 , pp. 169-190
    • Berdyshev, E.V.1
  • 81
    • 0028065110 scopus 로고
    • Secondary immunity to Legionella pneumophila and Th1 activity are suppressed by delta-9-tetrahydrocannabinol injection
    • Newton C.A., Klein T.W., Friedman H. Secondary immunity to Legionella pneumophila and Th1 activity are suppressed by delta-9-tetrahydrocannabinol injection. Infect Immun 1994, 62:4015-4020.
    • (1994) Infect Immun , vol.62 , pp. 4015-4020
    • Newton, C.A.1    Klein, T.W.2    Friedman, H.3
  • 82
    • 0034660138 scopus 로고    scopus 로고
    • Delta 9-tetrahydrocannabinol treatment suppresses immunity and early IFN-g, IL-12, and IL-12 receptor beta 2 responses to Legionella pneumophila infection
    • Klein T.W., Newton C.A., Nakachi N., Friedman H. Delta 9-tetrahydrocannabinol treatment suppresses immunity and early IFN-g, IL-12, and IL-12 receptor beta 2 responses to Legionella pneumophila infection. J Immunol 2000, 164:6461-6466.
    • (2000) J Immunol , vol.164 , pp. 6461-6466
    • Klein, T.W.1    Newton, C.A.2    Nakachi, N.3    Friedman, H.4
  • 83
    • 0034235808 scopus 로고    scopus 로고
    • Delta-9-tetrahydrocan-nabinol inhibits antitumor immunity by a CB2 receptor-mediated, cytokine-dependent pathway
    • Zhu L.X., Sharma S., Stolina M., et al. Delta-9-tetrahydrocan-nabinol inhibits antitumor immunity by a CB2 receptor-mediated, cytokine-dependent pathway. J Immunol 2000, 165:373-380.
    • (2000) J Immunol , vol.165 , pp. 373-380
    • Zhu, L.X.1    Sharma, S.2    Stolina, M.3
  • 84
    • 0036889699 scopus 로고    scopus 로고
    • Delta 9-tetrahydrocannabinol regulates Th1/Th2 cytokine balance in activated human T-cells
    • Yuan M., Kiertscher S.M., Cheng Q., Zoumalan R., Tashkin D.P., Roth M.D. Delta 9-tetrahydrocannabinol regulates Th1/Th2 cytokine balance in activated human T-cells. J Neuroimmunol 2002, 133:124-131.
    • (2002) J Neuroimmunol , vol.133 , pp. 124-131
    • Yuan, M.1    Kiertscher, S.M.2    Cheng, Q.3    Zoumalan, R.4    Tashkin, D.P.5    Roth, M.D.6
  • 85
    • 0027515373 scopus 로고
    • Molecular characterization of a peripheral receptor for cannabinoids
    • Munro S., Thomas K.L., Abu-Shaar M. Molecular characterization of a peripheral receptor for cannabinoids. Nature 1993, 365:61-65.
    • (1993) Nature , vol.365 , pp. 61-65
    • Munro, S.1    Thomas, K.L.2    Abu-Shaar, M.3
  • 87
    • 0018947105 scopus 로고
    • Chronic administration of cannabidiol to healthy volunteers and epileptic patients
    • Cunha J.M., Carlini E.A., Pereira A.E., et al. Chronic administration of cannabidiol to healthy volunteers and epileptic patients. Pharmacology 1980, 21:175-185.
    • (1980) Pharmacology , vol.21 , pp. 175-185
    • Cunha, J.M.1    Carlini, E.A.2    Pereira, A.E.3
  • 88
    • 0025837207 scopus 로고
    • Controlled clinical trial of cannabidiol in Huntington's disease
    • Consroe P., Laguna J., Allender J., et al. Controlled clinical trial of cannabidiol in Huntington's disease. Pharmacol Biochem Behav 1991, 40:701-708.
    • (1991) Pharmacol Biochem Behav , vol.40 , pp. 701-708
    • Consroe, P.1    Laguna, J.2    Allender, J.3
  • 89
    • 77954175124 scopus 로고    scopus 로고
    • Cannabinoid-induced apoptosis in immune cells as a pathway to immunosuppression
    • August
    • Rieder S.A., Chauhan A., Singh U., Nagarkatti M., Nagarkatti P. Cannabinoid-induced apoptosis in immune cells as a pathway to immunosuppression. Immunobiology August 2010, 215(8):598-605.
    • (2010) Immunobiology , vol.215 , Issue.8 , pp. 598-605
    • Rieder, S.A.1    Chauhan, A.2    Singh, U.3    Nagarkatti, M.4    Nagarkatti, P.5
  • 90
    • 0027999501 scopus 로고
    • Anandamide, an endogenous cannabinoid receptor agonist inhibits lymphocyte proliferation and induces apoptosis
    • Schwarz H., Blanco F.J., Lotz M. Anandamide, an endogenous cannabinoid receptor agonist inhibits lymphocyte proliferation and induces apoptosis. J Neuroimmunol 1994, 55(1):107-115.
    • (1994) J Neuroimmunol , vol.55 , Issue.1 , pp. 107-115
    • Schwarz, H.1    Blanco, F.J.2    Lotz, M.3
  • 91
    • 0034644769 scopus 로고    scopus 로고
    • Anandamide induces apoptosis in human cells via vanilloid receptors. Evidence for a protective role of cannabinoid receptors
    • Maccarrone M., Lorenzon T., Bari M., Melino G., Finazzi-Agro A. Anandamide induces apoptosis in human cells via vanilloid receptors. Evidence for a protective role of cannabinoid receptors. J Biol Chem 2000, 275(41):31938-31945.
    • (2000) J Biol Chem , vol.275 , Issue.41 , pp. 31938-31945
    • Maccarrone, M.1    Lorenzon, T.2    Bari, M.3    Melino, G.4    Finazzi-Agro, A.5
  • 92
    • 0032219623 scopus 로고    scopus 로고
    • Delta9-tetrahydrocannabinol induces apoptosis in macrophages and lymphocytes: involvement of bcl-2 and caspase-1
    • Zhu W., Friedman H., Klein T.W. Delta9-tetrahydrocannabinol induces apoptosis in macrophages and lymphocytes: involvement of bcl-2 and caspase-1. J Pharmacol Exp Ther 1998, 286(2):1103-1109.
    • (1998) J Pharmacol Exp Ther , vol.286 , Issue.2 , pp. 1103-1109
    • Zhu, W.1    Friedman, H.2    Klein, T.W.3
  • 93
    • 0036074054 scopus 로고    scopus 로고
    • Delta(9)-tetrahydrocannabinol-induced apoptosis in the thymus and spleen as a mechanism of immunosuppression in vitro and in vivo
    • McKallip R.J., Lombard C., Martin B.R., Nagarkatti M., Nagarkatti P.S. Delta(9)-tetrahydrocannabinol-induced apoptosis in the thymus and spleen as a mechanism of immunosuppression in vitro and in vivo. J Pharmacol Exp Ther 2002, 302(2):451-465.
    • (2002) J Pharmacol Exp Ther , vol.302 , Issue.2 , pp. 451-465
    • McKallip, R.J.1    Lombard, C.2    Martin, B.R.3    Nagarkatti, M.4    Nagarkatti, P.S.5
  • 94
    • 41149153235 scopus 로고    scopus 로고
    • A comparative study on cannabidiol-induced apoptosis in murine thymocytes and el-4 thymoma cells
    • Lee C.Y., Wey S.P., Liao M.H., Hsu W.L., Wu H.Y., Jan T.R. A comparative study on cannabidiol-induced apoptosis in murine thymocytes and el-4 thymoma cells. Int Immunopharmacol 2008, 8(5):732-740.
    • (2008) Int Immunopharmacol , vol.8 , Issue.5 , pp. 732-740
    • Lee, C.Y.1    Wey, S.P.2    Liao, M.H.3    Hsu, W.L.4    Wu, H.Y.5    Jan, T.R.6
  • 95
    • 0028979232 scopus 로고
    • Delta 9-tetrahydrocannabinol, cytokines, and immunity to Legionella pneumophila
    • Klein T.W., Newton C., Zhu W., Daaka Y., Friedman H. Delta 9-tetrahydrocannabinol, cytokines, and immunity to Legionella pneumophila. Proc Soc Exp Biol Med 1995, 209(3):205-212.
    • (1995) Proc Soc Exp Biol Med , vol.209 , Issue.3 , pp. 205-212
    • Klein, T.W.1    Newton, C.2    Zhu, W.3    Daaka, Y.4    Friedman, H.5
  • 96
    • 0029127449 scopus 로고
    • Cannabinoids enhance human b-cell growth at low nanomolar concentrations
    • Derocq J.M., Segui M., Marchand J., Le Fur G., Casellas P. Cannabinoids enhance human b-cell growth at low nanomolar concentrations. FEBS Lett 1995, 369(2-3):177-182.
    • (1995) FEBS Lett , vol.369 , Issue.2-3 , pp. 177-182
    • Derocq, J.M.1    Segui, M.2    Marchand, J.3    Le Fur, G.4    Casellas, P.5
  • 97
    • 0029127449 scopus 로고
    • Cannabinoids enhance human b-cell growth at low nanomolar concentrations
    • Derocq J.M., Segui M., Marchand J., Le Fur G., Casellas P. Cannabinoids enhance human b-cell growth at low nanomolar concentrations. FEBS Lett 1995, 369(2-3):177-182.
    • (1995) FEBS Lett , vol.369 , Issue.2-3 , pp. 177-182
    • Derocq, J.M.1    Segui, M.2    Marchand, J.3    Le Fur, G.4    Casellas, P.5
  • 98
    • 0026611540 scopus 로고
    • Delta 9-tetrahydrocannabinol suppresses concanavalin A induced increase in cytoplasmic free calcium in mouse thymocytes
    • Yebra M., Klein T.W., Friedman H. Delta 9-tetrahydrocannabinol suppresses concanavalin A induced increase in cytoplasmic free calcium in mouse thymocytes. Life Sci 1992, 51(2):151-160.
    • (1992) Life Sci , vol.51 , Issue.2 , pp. 151-160
    • Yebra, M.1    Klein, T.W.2    Friedman, H.3
  • 99
    • 33646404921 scopus 로고    scopus 로고
    • Cannabidiol lowers incidence of diabetes in non-obese diabetic mice
    • Weiss L., Zeira M., Reich S., Har-Noy M., Mechoulam R., Slavin S., et al. Cannabidiol lowers incidence of diabetes in non-obese diabetic mice. Autoimmunity 2006, 39(2):143-151.
    • (2006) Autoimmunity , vol.39 , Issue.2 , pp. 143-151
    • Weiss, L.1    Zeira, M.2    Reich, S.3    Har-Noy, M.4    Mechoulam, R.5    Slavin, S.6
  • 100
    • 0026046348 scopus 로고
    • Influence of marijuana components (THC and CBD) on human mononuclear cell cytokine secretion in vitro
    • Watzl B., Scuderi P., Watson R.R. Influence of marijuana components (THC and CBD) on human mononuclear cell cytokine secretion in vitro. Adv Exp Med Biol 1991, 288:63-70.
    • (1991) Adv Exp Med Biol , vol.288 , pp. 63-70
    • Watzl, B.1    Scuderi, P.2    Watson, R.R.3
  • 101
  • 102
    • 0037441460 scopus 로고    scopus 로고
    • Prospects for cannabinoids as anti-inflammatory agents
    • Zurier R.B. Prospects for cannabinoids as anti-inflammatory agents. J Cell Biochem 2003, 88:462-466.
    • (2003) J Cell Biochem , vol.88 , pp. 462-466
    • Zurier, R.B.1
  • 103
    • 0344505201 scopus 로고    scopus 로고
    • Drugs and immunity: cannabinoids and their role in decreased resistance to infectious disease
    • Cabral G.A., Dove Pettit D.A. Drugs and immunity: cannabinoids and their role in decreased resistance to infectious disease. J Neuroimmunol 1998, 83:116-123.
    • (1998) J Neuroimmunol , vol.83 , pp. 116-123
    • Cabral, G.A.1    Dove Pettit, D.A.2
  • 104
    • 42349104678 scopus 로고    scopus 로고
    • Cannabinomimetic control of mast cell mediator release: new perspective in chronic inflammation
    • De Filippis D., D'Amico A., Iuvone T. Cannabinomimetic control of mast cell mediator release: new perspective in chronic inflammation. J Neuroendocrinol 2008, 20(1):20-25.
    • (2008) J Neuroendocrinol , vol.20 , Issue.1 , pp. 20-25
    • De Filippis, D.1    D'Amico, A.2    Iuvone, T.3
  • 105
    • 41549162387 scopus 로고    scopus 로고
    • CB2 cannabinoid receptor agonist JWH-015 modulates human monocyte migration through defined intracellular signaling pathways
    • Montecucco F., Burger F., Mach F., Steffens S. CB2 cannabinoid receptor agonist JWH-015 modulates human monocyte migration through defined intracellular signaling pathways. Am J Physiol Heart Circ Physiol 2008, 294:H1145-H1155.
    • (2008) Am J Physiol Heart Circ Physiol , vol.294 , pp. H1145-H1155
    • Montecucco, F.1    Burger, F.2    Mach, F.3    Steffens, S.4
  • 106
    • 0037207092 scopus 로고    scopus 로고
    • Effects of delta-9-tetrahydrocannabinol on human immune function and host defense
    • Roth M.D., Baldwin G.C., Tashkin D.P. Effects of delta-9-tetrahydrocannabinol on human immune function and host defense. Chem Phys Lipids 2002, 121:229-239.
    • (2002) Chem Phys Lipids , vol.121 , pp. 229-239
    • Roth, M.D.1    Baldwin, G.C.2    Tashkin, D.P.3
  • 107
    • 33747373548 scopus 로고    scopus 로고
    • Cannabinoid-induced immune suppression and modulation of antigen-presenting cells
    • Klein T.W., Cabral G.A. Cannabinoid-induced immune suppression and modulation of antigen-presenting cells. J Neuroimmune Pharmacol 2006, 1:50-64.
    • (2006) J Neuroimmune Pharmacol , vol.1 , pp. 50-64
    • Klein, T.W.1    Cabral, G.A.2
  • 108
    • 77949690098 scopus 로고    scopus 로고
    • Cannabinoid inhibition of macrophage migration to the trans-activating (Tat) protein of HIV-1 is linked to the CB(2) cannabinoid receptor
    • Raborn E.S., Cabral G.A. Cannabinoid inhibition of macrophage migration to the trans-activating (Tat) protein of HIV-1 is linked to the CB(2) cannabinoid receptor. J Pharmacol Exp Ther 2010, 333:319-327.
    • (2010) J Pharmacol Exp Ther , vol.333 , pp. 319-327
    • Raborn, E.S.1    Cabral, G.A.2
  • 109
    • 52049093883 scopus 로고    scopus 로고
    • Endocannabinoids as positive or negative factors in hematopoietic cell migration and differentiation
    • Patinkin D., Milman G., Breuer A., Fride E., Mechoulam R. Endocannabinoids as positive or negative factors in hematopoietic cell migration and differentiation. Eur J Pharmacol 2008, 595:1-6.
    • (2008) Eur J Pharmacol , vol.595 , pp. 1-6
    • Patinkin, D.1    Milman, G.2    Breuer, A.3    Fride, E.4    Mechoulam, R.5
  • 110
    • 43449130045 scopus 로고    scopus 로고
    • The cannabinoid delta-9-tetrahydrocannabinol mediates inhibition of macrophage chemotaxis to RANTES/CCL5: linkage to the CB2 receptor
    • Raborn E.S., Marciano-Cabral F., Buckley N.E., Martin B.R., Cabral G.A. The cannabinoid delta-9-tetrahydrocannabinol mediates inhibition of macrophage chemotaxis to RANTES/CCL5: linkage to the CB2 receptor. J Neuroimmune Pharmacol 2008, 3:117-129.
    • (2008) J Neuroimmune Pharmacol , vol.3 , pp. 117-129
    • Raborn, E.S.1    Marciano-Cabral, F.2    Buckley, N.E.3    Martin, B.R.4    Cabral, G.A.5
  • 111
    • 38349086382 scopus 로고    scopus 로고
    • CB2 receptor-mediated migration of immune cells: it can go either way
    • Miller A.M., Stella N. CB2 receptor-mediated migration of immune cells: it can go either way. Br J Pharmacol 2008, 153:299-308.
    • (2008) Br J Pharmacol , vol.153 , pp. 299-308
    • Miller, A.M.1    Stella, N.2
  • 112
    • 0037442829 scopus 로고    scopus 로고
    • Nonpsychotropic cannabinoid receptors regulate microglial cell migration
    • Walter L., Franklin A., Witting A., Wade C., Xie Y., Kunos G., et al. Nonpsychotropic cannabinoid receptors regulate microglial cell migration. J Neurosci 2003, 23:1398-1405.
    • (2003) J Neurosci , vol.23 , pp. 1398-1405
    • Walter, L.1    Franklin, A.2    Witting, A.3    Wade, C.4    Xie, Y.5    Kunos, G.6
  • 113
    • 84878980801 scopus 로고    scopus 로고
    • Differential migratory properties of monocytes isolated from human subjects naïve and non-naïve to cannabis
    • June
    • Sexton M., Silvestroni A., Moller T., Stella N. Differential migratory properties of monocytes isolated from human subjects naïve and non-naïve to cannabis. Inflammopharmacology June 2013, 21(3):253-259.
    • (2013) Inflammopharmacology , vol.21 , Issue.3 , pp. 253-259
    • Sexton, M.1    Silvestroni, A.2    Moller, T.3    Stella, N.4
  • 114
    • 33749014963 scopus 로고    scopus 로고
    • Cannabinoid treatment suppresses the t-helper cell-polarizing function of mouse dendritic cells stimulated with Legionella pneumophila infection
    • Lu T., Newton C., Perkins I., Friedman H., Klein T.W. Cannabinoid treatment suppresses the t-helper cell-polarizing function of mouse dendritic cells stimulated with Legionella pneumophila infection. J Pharmacol Exp Ther 2006, 319(1):269-276.
    • (2006) J Pharmacol Exp Ther , vol.319 , Issue.1 , pp. 269-276
    • Lu, T.1    Newton, C.2    Perkins, I.3    Friedman, H.4    Klein, T.W.5
  • 115
    • 45749086074 scopus 로고    scopus 로고
    • Attenuation of experimental autoimmune hepatitis by exogenous and endogenous cannabinoids: involvement of regulatory t cells
    • Hegde V.L., Hegde S., Cravatt B.F., Hofseth L.J., Nagarkatti M., Nagarkatti P.S. Attenuation of experimental autoimmune hepatitis by exogenous and endogenous cannabinoids: involvement of regulatory t cells. Mol Pharmacol 2008, 74(1):20-33.
    • (2008) Mol Pharmacol , vol.74 , Issue.1 , pp. 20-33
    • Hegde, V.L.1    Hegde, S.2    Cravatt, B.F.3    Hofseth, L.J.4    Nagarkatti, M.5    Nagarkatti, P.S.6
  • 116
    • 8444244202 scopus 로고    scopus 로고
    • Effect of cannabinoid ingestion (in the form of bhang) on the immune system of high school and university students
    • El-Gohary M., Eid M.A. Effect of cannabinoid ingestion (in the form of bhang) on the immune system of high school and university students. Hum Exp Toxicol 2004, 23:149-156.
    • (2004) Hum Exp Toxicol , vol.23 , pp. 149-156
    • El-Gohary, M.1    Eid, M.A.2
  • 118
    • 0035191240 scopus 로고    scopus 로고
    • Differential expression of the CB2 cannabinoid receptor by rodent macrophages and macrophage-like cells in relation to cell activation
    • Carlisle S.J., Marciano-Cabral F., Staab A., Ludwick C., Cabral G.A. Differential expression of the CB2 cannabinoid receptor by rodent macrophages and macrophage-like cells in relation to cell activation. Int Immunopharmacol 2002, 2:69-82.
    • (2002) Int Immunopharmacol , vol.2 , pp. 69-82
    • Carlisle, S.J.1    Marciano-Cabral, F.2    Staab, A.3    Ludwick, C.4    Cabral, G.A.5
  • 119
    • 22044449933 scopus 로고    scopus 로고
    • Activation of cannabinoid CB2 receptor negatively regulates IL-12p40 production in murine macrophages: role of IL-10 and ERK1/2 kinase signaling
    • Correa F., Mestre L., Docagne F., Guaza C. Activation of cannabinoid CB2 receptor negatively regulates IL-12p40 production in murine macrophages: role of IL-10 and ERK1/2 kinase signaling. Br J Pharmacol 2005, 145:441-448.
    • (2005) Br J Pharmacol , vol.145 , pp. 441-448
    • Correa, F.1    Mestre, L.2    Docagne, F.3    Guaza, C.4
  • 120
    • 27744493300 scopus 로고    scopus 로고
    • 2-Arachidonoylglycerol, an endogenous cannabinoid receptor ligand, enhances the adhesion of HL-60 cells differentiated into macrophage-like cells and human peripheral blood monocytes
    • Gokoh M., Kishimoto S., Oka S., Metani Y., Sugiura T. 2-Arachidonoylglycerol, an endogenous cannabinoid receptor ligand, enhances the adhesion of HL-60 cells differentiated into macrophage-like cells and human peripheral blood monocytes. FEBS Lett 2005, 579:6473-6478.
    • (2005) FEBS Lett , vol.579 , pp. 6473-6478
    • Gokoh, M.1    Kishimoto, S.2    Oka, S.3    Metani, Y.4    Sugiura, T.5
  • 121
    • 26844448746 scopus 로고    scopus 로고
    • Modulation of the cannabinoid CB2 receptor in microglial cells in response to inflammatory stimuli
    • Maresz K., Carrier E.J., Ponomarev E.D., Hillard C.J., Dittel B.N. Modulation of the cannabinoid CB2 receptor in microglial cells in response to inflammatory stimuli. J Neurochem 2005, 95:437-445.
    • (2005) J Neurochem , vol.95 , pp. 437-445
    • Maresz, K.1    Carrier, E.J.2    Ponomarev, E.D.3    Hillard, C.J.4    Dittel, B.N.5
  • 122
    • 0024563469 scopus 로고
    • Delta-9-tetrahydrocannabinol inhibits macrophage protein expression in response to bacterial immunomodulators
    • Cabral G.A., Mishkin E.M. Delta-9-tetrahydrocannabinol inhibits macrophage protein expression in response to bacterial immunomodulators. J Toxicol Environ Health 1989, 26(2):175-182.
    • (1989) J Toxicol Environ Health , vol.26 , Issue.2 , pp. 175-182
    • Cabral, G.A.1    Mishkin, E.M.2
  • 123
    • 0022495566 scopus 로고
    • Tetrahydrocannabinol-induced suppression of macrophage spreading and phagocytic activity in vitro
    • Lopez-Cepero M., Friedman M., Klein T., Friedman H. Tetrahydrocannabinol-induced suppression of macrophage spreading and phagocytic activity in vitro. J Leukoc Biol 1986, 39(6):679-686.
    • (1986) J Leukoc Biol , vol.39 , Issue.6 , pp. 679-686
    • Lopez-Cepero, M.1    Friedman, M.2    Klein, T.3    Friedman, H.4
  • 124
    • 0028979327 scopus 로고
    • Delta 9-tetrahydrocannabinol modulates antigen processing by macrophages
    • McCoy K.L., Gainey D., Cabral G.A. Delta 9-tetrahydrocannabinol modulates antigen processing by macrophages. J Pharmacol Exp Ther 1995, 273(3):1216-1223.
    • (1995) J Pharmacol Exp Ther , vol.273 , Issue.3 , pp. 1216-1223
    • McCoy, K.L.1    Gainey, D.2    Cabral, G.A.3
  • 125
    • 0025914817 scopus 로고
    • Selective inhibition of natural killer but not natural cytotoxic activity in a cloned cell line by delta-9-tetrahydrocannabinol
    • Wang M., Richards A.L., Friedman H., Djeu J.Y. Selective inhibition of natural killer but not natural cytotoxic activity in a cloned cell line by delta-9-tetrahydrocannabinol. J Leukoc Biol 1991, 50:192-197.
    • (1991) J Leukoc Biol , vol.50 , pp. 192-197
    • Wang, M.1    Richards, A.L.2    Friedman, H.3    Djeu, J.Y.4
  • 126
    • 0026516862 scopus 로고
    • Suppressive effect of tetrahydrocannabinol on specific T cell subpopulations in the thymus
    • Pross S., Nakano Y., Smith J., Widen R., Rodriguez A., Newton C., et al. Suppressive effect of tetrahydrocannabinol on specific T cell subpopulations in the thymus. Thymus 1992, 19:97-104.
    • (1992) Thymus , vol.19 , pp. 97-104
    • Pross, S.1    Nakano, Y.2    Smith, J.3    Widen, R.4    Rodriguez, A.5    Newton, C.6
  • 127
    • 0026623545 scopus 로고
    • Delta 9-tetrahydrocannabinol decreases cytotoxic T lymphocyte activity to herpes simplex virus type 1-infected cells
    • Fischer-Stenger K., Updegrove A.W., Cabral G.A. Delta 9-tetrahydrocannabinol decreases cytotoxic T lymphocyte activity to herpes simplex virus type 1-infected cells. Proc Soc Exp Biol Med 1992, 200:422-430.
    • (1992) Proc Soc Exp Biol Med , vol.200 , pp. 422-430
    • Fischer-Stenger, K.1    Updegrove, A.W.2    Cabral, G.A.3
  • 129
    • 77950501675 scopus 로고    scopus 로고
    • Anti-inflammatory potential of CB1-mediated cAMP elevation in mast cells
    • Small-Howard A.L., Shimoda L.M., Adra C.N., Turner H. Anti-inflammatory potential of CB1-mediated cAMP elevation in mast cells. Biochem J 2005, 25:25.
    • (2005) Biochem J , vol.25 , pp. 25
    • Small-Howard, A.L.1    Shimoda, L.M.2    Adra, C.N.3    Turner, H.4
  • 130
    • 33845811458 scopus 로고    scopus 로고
    • Involvement of cannabinoid CB2 receptors in the IgE-mediated triphasic cutaneous reaction in mice
    • Ueda Y., Miyagawa N., Wakitani K. Involvement of cannabinoid CB2 receptors in the IgE-mediated triphasic cutaneous reaction in mice. Life Sci 2007, 80:414-419.
    • (2007) Life Sci , vol.80 , pp. 414-419
    • Ueda, Y.1    Miyagawa, N.2    Wakitani, K.3
  • 131
    • 0242304878 scopus 로고    scopus 로고
    • Cannabinoids inhibit neurodegeneration in models of multiple sclerosis
    • Pryce G., Ahmed Z., Hankey D.J., Jackson S.J., Croxford J.L., Pocock J.M., et al. Cannabinoids inhibit neurodegeneration in models of multiple sclerosis. Brain 2003, 126(Pt10):2191-2202.
    • (2003) Brain , vol.126 , pp. 2191-2202
    • Pryce, G.1    Ahmed, Z.2    Hankey, D.J.3    Jackson, S.J.4    Croxford, J.L.5    Pocock, J.M.6
  • 132
    • 12444273710 scopus 로고    scopus 로고
    • New perspectives in the studies on endocannabinoid and cannabis: abnormal behaviors associate with CB1 cannabinoid receptor and development of therapeutic application
    • Fujiwara M., Egashira N. New perspectives in the studies on endocannabinoid and cannabis: abnormal behaviors associate with CB1 cannabinoid receptor and development of therapeutic application. J Pharmacol Sci 2004, 96(4):362-366.
    • (2004) J Pharmacol Sci , vol.96 , Issue.4 , pp. 362-366
    • Fujiwara, M.1    Egashira, N.2
  • 133
    • 21744455710 scopus 로고    scopus 로고
    • Cannabinoid-receptor 1 null mice are susceptible to neurofilament damage and caspase 3 activation
    • Jackson S.J., Pryce G., Diemel L.T., Cuzner M.L., Baker D. Cannabinoid-receptor 1 null mice are susceptible to neurofilament damage and caspase 3 activation. Neuroscience 2005, 134(1):261-268.
    • (2005) Neuroscience , vol.134 , Issue.1 , pp. 261-268
    • Jackson, S.J.1    Pryce, G.2    Diemel, L.T.3    Cuzner, M.L.4    Baker, D.5
  • 134
    • 33847119449 scopus 로고    scopus 로고
    • Control of spasticity in a multiple sclerosis model is mediated by CB1, not CB2, cannabinoid receptors
    • Pryce G., Baker D. Control of spasticity in a multiple sclerosis model is mediated by CB1, not CB2, cannabinoid receptors. Br J Pharmacol 2007, 150(4):519-525.
    • (2007) Br J Pharmacol , vol.150 , Issue.4 , pp. 519-525
    • Pryce, G.1    Baker, D.2
  • 135
    • 26944483132 scopus 로고    scopus 로고
    • Decreased endocannabinoid levels in the brain and beneficial effects of agents activating cannabinoid and/or vanilloid receptors in a rat model of multiple sclerosis
    • Cabranes A., Venderova K., de Lago E., Fezza F., Sanchez A., Mestre L., et al. Decreased endocannabinoid levels in the brain and beneficial effects of agents activating cannabinoid and/or vanilloid receptors in a rat model of multiple sclerosis. J Neurobiol Dis 2005, 20(2):207-217.
    • (2005) J Neurobiol Dis , vol.20 , Issue.2 , pp. 207-217
    • Cabranes, A.1    Venderova, K.2    de Lago, E.3    Fezza, F.4    Sanchez, A.5    Mestre, L.6
  • 136
    • 17144462251 scopus 로고    scopus 로고
    • Therapeutic action of cannabinoids in a murine model of multiple sclerosis
    • Arevalo-Martin A., Vela J.M., Molina-Holgado E., Borrell J., Guaza C. Therapeutic action of cannabinoids in a murine model of multiple sclerosis. J Neurosci 2003, 23(7):2511-2516.
    • (2003) J Neurosci , vol.23 , Issue.7 , pp. 2511-2516
    • Arevalo-Martin, A.1    Vela, J.M.2    Molina-Holgado, E.3    Borrell, J.4    Guaza, C.5
  • 137
    • 29544446576 scopus 로고    scopus 로고
    • The endocannabinoid anandamide protects neurons during CNS inflammation by induction of MKP-1 in microglial cells
    • Eljaschewitsch E., Witting A., Mawrin C., Lee T., Schmidt P.M., Wolf S., et al. The endocannabinoid anandamide protects neurons during CNS inflammation by induction of MKP-1 in microglial cells. Neuron 2006, 49(1):67-79.
    • (2006) Neuron , vol.49 , Issue.1 , pp. 67-79
    • Eljaschewitsch, E.1    Witting, A.2    Mawrin, C.3    Lee, T.4    Schmidt, P.M.5    Wolf, S.6
  • 138
    • 84923138341 scopus 로고    scopus 로고
    • The Cannabinoid Use in Progressive Inflammatory brain Disease (CUPID) trial: a randomised double-blind placebo-controlled parallel-group multicentre trial and economic evaluation of cannabinoids to slow progression in multiple sclerosis
    • Ball S., Vickery J., Hobart J., Wright D., Green C., Shearer J., et al. The Cannabinoid Use in Progressive Inflammatory brain Disease (CUPID) trial: a randomised double-blind placebo-controlled parallel-group multicentre trial and economic evaluation of cannabinoids to slow progression in multiple sclerosis. Health Technol Assess 2015, 19. (ISSN 1366-5278).
    • (2015) Health Technol Assess , vol.19
    • Ball, S.1    Vickery, J.2    Hobart, J.3    Wright, D.4    Green, C.5    Shearer, J.6
  • 140
    • 63549096654 scopus 로고    scopus 로고
    • Cannabinoid-induced effects on the nociceptive system: a neurophysiological study in patients with secondary progressive multiple sclerosis
    • May
    • Conte A., CM Bettolo, Onesti E., Frasca V., Iacovelli E., Gilio F., et al. Cannabinoid-induced effects on the nociceptive system: a neurophysiological study in patients with secondary progressive multiple sclerosis. Eur J Pain May 2009, 13(5). (472-7).
    • (2009) Eur J Pain , vol.13 , Issue.5 , pp. 472-477
    • Conte, A.1    Bettolo, C.M.2    Onesti, E.3    Frasca, V.4    Iacovelli, E.5    Gilio, F.6
  • 141
    • 33847766180 scopus 로고    scopus 로고
    • Sativex spasticity in MS Study Group. randomized controlled trial of cannabis-based medicine in spasticity caused by multiple sclerosis
    • Collin C., Davies P., Mutiboko I.K., Ratcliffe S. Sativex spasticity in MS Study Group. randomized controlled trial of cannabis-based medicine in spasticity caused by multiple sclerosis. Eur J Neurol 2007 Mar, 14(3):290-296.
    • (2007) Eur J Neurol , vol.14 , Issue.3 , pp. 290-296
    • Collin, C.1    Davies, P.2    Mutiboko, I.K.3    Ratcliffe, S.4
  • 142
    • 80052032038 scopus 로고    scopus 로고
    • Inflammation in osteoarthritis
    • Goldring M.B., Otero M. Inflammation in osteoarthritis. Curr Rheumatol 2011, 23:471-478.
    • (2011) Curr Rheumatol , vol.23 , pp. 471-478
    • Goldring, M.B.1    Otero, M.2
  • 143
    • 1542283741 scopus 로고    scopus 로고
    • A novel synthetic, nonpsychoactive cannabinoid acid (HU-320) with antiinflammatory properties in murine collagen-induced arthritis
    • Sumariwalla P.F., Gallily R., Tchilibon S., Fride E., Mechoulam R., Feldmann M. A novel synthetic, nonpsychoactive cannabinoid acid (HU-320) with antiinflammatory properties in murine collagen-induced arthritis. Arthritis Rheum 2004, 50:985-998.
    • (2004) Arthritis Rheum , vol.50 , pp. 985-998
    • Sumariwalla, P.F.1    Gallily, R.2    Tchilibon, S.3    Fride, E.4    Mechoulam, R.5    Feldmann, M.6
  • 144
    • 0031962165 scopus 로고    scopus 로고
    • Dimethylheptyl-THC-11 oic acid: a nonpsychoactive antiinflammatory agent with a cannabinoid template structure
    • Zurier R.B., Rossetti R.G., Lane J.H., Goldberg J.M., Hunter S.A., Burstein S.H. Dimethylheptyl-THC-11 oic acid: a nonpsychoactive antiinflammatory agent with a cannabinoid template structure. Arthritis Rheum 1998, 41:163-170.
    • (1998) Arthritis Rheum , vol.41 , pp. 163-170
    • Zurier, R.B.1    Rossetti, R.G.2    Lane, J.H.3    Goldberg, J.M.4    Hunter, S.A.5    Burstein, S.H.6
  • 145
    • 0034662868 scopus 로고    scopus 로고
    • The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis
    • Malfait A.M., Gallily R., Sumariwalla P.F., Malik A.S., Andreakos E., Mechoulam R., et al. The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis. Proc Natl Acad Sci U S A 2000, 97:9561-9566.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 9561-9566
    • Malfait, A.M.1    Gallily, R.2    Sumariwalla, P.F.3    Malik, A.S.4    Andreakos, E.5    Mechoulam, R.6
  • 146
    • 0037441413 scopus 로고    scopus 로고
    • Suppression of human monocyte interleukin-1beta production by ajulemic acid, a nonpsychoactive cannabinoid
    • Zurier R.B., Rossetti R.G., Burstein S.H., Bidinger B. Suppression of human monocyte interleukin-1beta production by ajulemic acid, a nonpsychoactive cannabinoid. Biochem Pharmacol 2003, 65:649-655.
    • (2003) Biochem Pharmacol , vol.65 , pp. 649-655
    • Zurier, R.B.1    Rossetti, R.G.2    Burstein, S.H.3    Bidinger, B.4
  • 147
    • 52649089192 scopus 로고    scopus 로고
    • Inhibitory effect of synthetic cannabinoids on cytokine production in rheumatoid fibroblast-like synoviocytes
    • Selvi E., Lorenzini S., Garcia-Gonzalez E., Maggio R., Lazzerini P.E., Capecchi P.L., et al. Inhibitory effect of synthetic cannabinoids on cytokine production in rheumatoid fibroblast-like synoviocytes. Clin Exp Rheumatol 2008, 26:574-581.
    • (2008) Clin Exp Rheumatol , vol.26 , pp. 574-581
    • Selvi, E.1    Lorenzini, S.2    Garcia-Gonzalez, E.3    Maggio, R.4    Lazzerini, P.E.5    Capecchi, P.L.6
  • 148
    • 33845632330 scopus 로고    scopus 로고
    • Suppression of fibroblast metalloproteinases by ajulemic acid, a nonpsychoactive cannabinoid acid
    • Johnson D.R., Stebulis J.A., Rossetti R.G., Burstein S.H., Zurier R.B. Suppression of fibroblast metalloproteinases by ajulemic acid, a nonpsychoactive cannabinoid acid. J Cell Biochem 2007, 100:184-190.
    • (2007) J Cell Biochem , vol.100 , pp. 184-190
    • Johnson, D.R.1    Stebulis, J.A.2    Rossetti, R.G.3    Burstein, S.H.4    Zurier, R.B.5
  • 149
    • 33644766857 scopus 로고    scopus 로고
    • Arthritis and cannabinoids: HU-210 and Win-55,212-2 prevent IL-1alphainduced matrix degradation in bovine articular chondrocytes in-vitro
    • Mbvundula E.C., Bunning R.A., Rainsford K.D. Arthritis and cannabinoids: HU-210 and Win-55,212-2 prevent IL-1alphainduced matrix degradation in bovine articular chondrocytes in-vitro. J Pharm Pharmacol 2006, 58:351-358.
    • (2006) J Pharm Pharmacol , vol.58 , pp. 351-358
    • Mbvundula, E.C.1    Bunning, R.A.2    Rainsford, K.D.3
  • 152
    • 77954175115 scopus 로고    scopus 로고
    • Cannabinoid activation of peroxisome proliferator-activated receptors: potential for modulation of inflammatory disease
    • O'Sullivan S.E., Kendall D.A. Cannabinoid activation of peroxisome proliferator-activated receptors: potential for modulation of inflammatory disease. Immunobiology 2010, 215:611e6.
    • (2010) Immunobiology , vol.215
    • O'Sullivan, S.E.1    Kendall, D.A.2
  • 153
    • 1542283741 scopus 로고    scopus 로고
    • Ester; a novel synthetic, nonpsychoactive cannabinoid acid (HU-320) with antiinflammatory properties in murine collagen-induced arthritis
    • March
    • Sumariwalla, Percy F., Gallily Ruth, Tchilibon Susanna Ester; a novel synthetic, nonpsychoactive cannabinoid acid (HU-320) with antiinflammatory properties in murine collagen-induced arthritis. Arthritis Rheum March 2004, 50(3):985-998.
    • (2004) Arthritis Rheum , vol.50 , Issue.3 , pp. 985-998
    • Sumariwalla, P.F.1    Gallily, R.2    Tchilibon, S.3
  • 154
    • 34347342722 scopus 로고    scopus 로고
    • Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors
    • Agarwal N., Pacher P., Tegeder I., Amaya F., Constantin C.E., Brenner G.J., et al. Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors. Nat Neurosci 2007, 10:870-879.
    • (2007) Nat Neurosci , vol.10 , pp. 870-879
    • Agarwal, N.1    Pacher, P.2    Tegeder, I.3    Amaya, F.4    Constantin, C.E.5    Brenner, G.J.6
  • 155
    • 78651430475 scopus 로고    scopus 로고
    • A double-blind, randomized, placebocontrolled study of the efficacy and safety of duloxetine for the treatment of chronic pain due to osteoarthritis of the knee
    • Chappell A.S., Desaiah D., Liu-Seifert H., Zhang S., Skljarevski V., Belenkov Y., et al. A double-blind, randomized, placebocontrolled study of the efficacy and safety of duloxetine for the treatment of chronic pain due to osteoarthritis of the knee. Pain Pract 2001, 11:33-41.
    • (2001) Pain Pract , vol.11 , pp. 33-41
    • Chappell, A.S.1    Desaiah, D.2    Liu-Seifert, H.3    Zhang, S.4    Skljarevski, V.5    Belenkov, Y.6
  • 156
    • 0035081251 scopus 로고    scopus 로고
    • Cannabinoid inhibition of the capsaicin-induced calcium response in rat dorsal root ganglion neurones
    • Millns P.J., Chapman V., Kendall D.A. Cannabinoid inhibition of the capsaicin-induced calcium response in rat dorsal root ganglion neurones. Brit J Pharmacol 2001, 132:969-971.
    • (2001) Brit J Pharmacol , vol.132 , pp. 969-971
    • Millns, P.J.1    Chapman, V.2    Kendall, D.A.3
  • 157
    • 50349097911 scopus 로고    scopus 로고
    • Cannabinoid receptor CB2 localisation and agonist-mediated inhibition of capsaicin responses in human sensory neurons
    • Anand U., Otto W.R., Sanchez-Herrera D., Facer P., Yiangou Y., Korchev Y., et al. Cannabinoid receptor CB2 localisation and agonist-mediated inhibition of capsaicin responses in human sensory neurons. Pain 2008, 138:667-680.
    • (2008) Pain , vol.138 , pp. 667-680
    • Anand, U.1    Otto, W.R.2    Sanchez-Herrera, D.3    Facer, P.4    Yiangou, Y.5    Korchev, Y.6
  • 158
    • 0032563792 scopus 로고    scopus 로고
    • An analgesia circuit activated by cannabinoids
    • Meng I.D., Manning B.H., Martin W.J., Fields H.L. An analgesia circuit activated by cannabinoids. Nature 1998, 395:381-383.
    • (1998) Nature , vol.395 , pp. 381-383
    • Meng, I.D.1    Manning, B.H.2    Martin, W.J.3    Fields, H.L.4
  • 159
    • 38149076483 scopus 로고    scopus 로고
    • Cannabinoid-mediated antinociception is enhanced in rat osteoarthritic knees
    • Schuelert N., McDougall J.J. Cannabinoid-mediated antinociception is enhanced in rat osteoarthritic knees. Arthritis Rheum 2008, 58:145-153.
    • (2008) Arthritis Rheum , vol.58 , pp. 145-153
    • Schuelert, N.1    McDougall, J.J.2
  • 160
    • 43249115359 scopus 로고    scopus 로고
    • Characterisation of the cannabinoid receptor system in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis
    • Richardson D., Pearson R.G., Kurian N., Latif M.L., Garle M.J., Barrett D.A., et al. Characterisation of the cannabinoid receptor system in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis. Arthritis Res Ther 2008, 10:R43.
    • (2008) Arthritis Res Ther , vol.10 , pp. R43
    • Richardson, D.1    Pearson, R.G.2    Kurian, N.3    Latif, M.L.4    Garle, M.J.5    Barrett, D.A.6
  • 161
    • 78649878693 scopus 로고    scopus 로고
    • Tonic modulation of spinal hyperexcitability by the endocannabinoid receptor system in a rat model of osteoarthritis pain
    • Sagar D.R., Staniaszek L.E., Okine B.N., Woodhams S., Norris L.M., Pearson R.G., et al. Tonic modulation of spinal hyperexcitability by the endocannabinoid receptor system in a rat model of osteoarthritis pain. Arthritis Rheum 2010, 62:3666-3676.
    • (2010) Arthritis Rheum , vol.62 , pp. 3666-3676
    • Sagar, D.R.1    Staniaszek, L.E.2    Okine, B.N.3    Woodhams, S.4    Norris, L.M.5    Pearson, R.G.6
  • 162
    • 29844435136 scopus 로고    scopus 로고
    • Preliminary assessment of the efficacy, tolerability and safety of a cannabis based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis
    • Blake D.R., et al. Preliminary assessment of the efficacy, tolerability and safety of a cannabis based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis. Rheumatology 2006, 45(1):50-52.
    • (2006) Rheumatology , vol.45 , Issue.1 , pp. 50-52
    • Blake, D.R.1
  • 163
    • 79960288214 scopus 로고    scopus 로고
    • Cannabinoids for treatment of chronic non-cancer pain; a systematic review of randomized trials
    • Lynch M.E., Campbell F. Cannabinoids for treatment of chronic non-cancer pain; a systematic review of randomized trials. Br J Clin Pharmacol 2011 Nov, 72(5):735-744.
    • (2011) Br J Clin Pharmacol , vol.72 , Issue.5 , pp. 735-744
    • Lynch, M.E.1    Campbell, F.2
  • 164
    • 2342459078 scopus 로고    scopus 로고
    • Serological assessment of type I collagen burden in scleroderma spectrum disorders: a systematic review
    • Dziadzio M., Smith E., Abraham D.J., et al. Serological assessment of type I collagen burden in scleroderma spectrum disorders: a systematic review. Clin Exp Rheumatol 2004, 22:356-367.
    • (2004) Clin Exp Rheumatol , vol.22 , pp. 356-367
    • Dziadzio, M.1    Smith, E.2    Abraham, D.J.3
  • 165
    • 0025989368 scopus 로고
    • Stimulation of collagen and glycosaminoglycan production in cultured human adult dermal fibroblasts by recombinant human interleukin 6
    • Duncan M.R., Berman B. Stimulation of collagen and glycosaminoglycan production in cultured human adult dermal fibroblasts by recombinant human interleukin 6. J Invest Dermatol 1991, 97:686-692.
    • (1991) J Invest Dermatol , vol.97 , pp. 686-692
    • Duncan, M.R.1    Berman, B.2
  • 166
    • 4644226099 scopus 로고    scopus 로고
    • Cannabinoids down-regulate PI3K/akt and Erk signalling pathways and activate proapoptotic function of bad protein
    • Ellert-Miklaszewska A., Kaminska B., Konarska L. Cannabinoids down-regulate PI3K/akt and Erk signalling pathways and activate proapoptotic function of bad protein. Cell Signal 2005, 17:25-37.
    • (2005) Cell Signal , vol.17 , pp. 25-37
    • Ellert-Miklaszewska, A.1    Kaminska, B.2    Konarska, L.3
  • 168
    • 18844400058 scopus 로고    scopus 로고
    • Cannabinoid-based drugs as anti-inflammatory therapeutics
    • Klein T.W. Cannabinoid-based drugs as anti-inflammatory therapeutics. Nat Rev Immunol 2005, 5:400-411.
    • (2005) Nat Rev Immunol , vol.5 , pp. 400-411
    • Klein, T.W.1
  • 169
    • 84862575210 scopus 로고    scopus 로고
    • Adenosine A2A receptor activation stimulates Collagen production in sclerodermic dermal fibroblasts either directly and through a cross-talk with the cannabinoid system
    • Lazzerini P.E., Natale M., Gianchecchi E., et al. Adenosine A2A receptor activation stimulates Collagen production in sclerodermic dermal fibroblasts either directly and through a cross-talk with the cannabinoid system. J Mol Med (Berl) 2012, 90:331-342.
    • (2012) J Mol Med (Berl) , vol.90 , pp. 331-342
    • Lazzerini, P.E.1    Natale, M.2    Gianchecchi, E.3
  • 170
    • 84864869606 scopus 로고    scopus 로고
    • Synthetic cannabinoid ajulemic acid exerts potent antifibrotic effects in experimental models of systemic sclerosis
    • Gonzalez E.G., Selvi E., Balistreri E., et al. Synthetic cannabinoid ajulemic acid exerts potent antifibrotic effects in experimental models of systemic sclerosis. Ann Rheum Dis 2012, 71:1545-1551.
    • (2012) Ann Rheum Dis , vol.71 , pp. 1545-1551
    • Gonzalez, E.G.1    Selvi, E.2    Balistreri, E.3
  • 171
    • 0033001488 scopus 로고    scopus 로고
    • The NOD mouse model of type 1 diabetes: as good as it gets?
    • Atkinson M.A., Leiter E.H. The NOD mouse model of type 1 diabetes: as good as it gets?. Nat Med 1999, 5:601-604.
    • (1999) Nat Med , vol.5 , pp. 601-604
    • Atkinson, M.A.1    Leiter, E.H.2
  • 172
    • 1842470094 scopus 로고    scopus 로고
    • Beta cell death and protection
    • Mandrup-Poulsen T. Beta cell death and protection. Ann N Y Acad Sci 2003, 1005:32-42.
    • (2003) Ann N Y Acad Sci , vol.1005 , pp. 32-42
    • Mandrup-Poulsen, T.1
  • 173
    • 79955632246 scopus 로고    scopus 로고
    • Cannabinoids and endocannabinoids in metabolic disorders with focus on diabetes
    • Di Marzo V., Piscitelli F., Mechoulam R. Cannabinoids and endocannabinoids in metabolic disorders with focus on diabetes. Handb Exp Pharmacol 2011, 203:75-104.
    • (2011) Handb Exp Pharmacol , vol.203 , pp. 75-104
    • Di Marzo, V.1    Piscitelli, F.2    Mechoulam, R.3
  • 174
    • 37349096614 scopus 로고    scopus 로고
    • Cannabidiol arrests onset of autoimmune diabetes in NOD mice
    • Weiss L., Zeira M., Reich S., et al. Cannabidiol arrests onset of autoimmune diabetes in NOD mice. Neuropharmacol 2008, 54:244-249.
    • (2008) Neuropharmacol , vol.54 , pp. 244-249
    • Weiss, L.1    Zeira, M.2    Reich, S.3
  • 175
    • 0033088881 scopus 로고    scopus 로고
    • Current concept of the pathogenesis of autoimmune type 1 diabetes mellitus
    • Satoh J., Takahashi K., Nakazawa T., Sakata Y., Toyota T. Current concept of the pathogenesis of autoimmune type 1 diabetes mellitus. Nippon Rinsho 1999, 57:528-533.
    • (1999) Nippon Rinsho , vol.57 , pp. 528-533
    • Satoh, J.1    Takahashi, K.2    Nakazawa, T.3    Sakata, Y.4    Toyota, T.5
  • 176
    • 0029351113 scopus 로고
    • T-cell subsets. Who does the polarizing?
    • Swain S.L. T-cell subsets. Who does the polarizing?. Curr Biol 1995, 5:849-851.
    • (1995) Curr Biol , vol.5 , pp. 849-851
    • Swain, S.L.1
  • 177
    • 0032960249 scopus 로고    scopus 로고
    • Absolute requirement of macrophages for the development and activation of beta-cell cytotoxic CD8+T-cells in T-cell receptor transgenic NOD mice
    • Jun H.S., Santamaria P., Lim H.W., Zhang M.L., Yoon J.W. Absolute requirement of macrophages for the development and activation of beta-cell cytotoxic CD8+T-cells in T-cell receptor transgenic NOD mice. Diabetes 1999, 48:34-42.
    • (1999) Diabetes , vol.48 , pp. 34-42
    • Jun, H.S.1    Santamaria, P.2    Lim, H.W.3    Zhang, M.L.4    Yoon, J.W.5
  • 178
    • 0037313578 scopus 로고    scopus 로고
    • Interleukin-12 and the regulation of innate resistance and adaptive immunity
    • Trinchieri G. Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nat Rev Immunol 2003, 3:133-146.
    • (2003) Nat Rev Immunol , vol.3 , pp. 133-146
    • Trinchieri, G.1
  • 179
    • 0030051658 scopus 로고    scopus 로고
    • Regulation of murine macrophage IL-12 production. Activation of macrophages in vivo, restimulation in vitro, and modulation by other cytokines
    • Skeen M.J., Miller M.A., Shinnick T.M., Ziegler H.K. Regulation of murine macrophage IL-12 production. Activation of macrophages in vivo, restimulation in vitro, and modulation by other cytokines. J Immunol 1996, 156:1196-1206.
    • (1996) J Immunol , vol.156 , pp. 1196-1206
    • Skeen, M.J.1    Miller, M.A.2    Shinnick, T.M.3    Ziegler, H.K.4
  • 180
    • 0027369747 scopus 로고
    • In vitro production of interleukin-1, interleukin-6, and tumor necrosis factor-alpha in insulin-dependent diabetes mellitus
    • Ohno Y., Aoki N., Nishimura A. In vitro production of interleukin-1, interleukin-6, and tumor necrosis factor-alpha in insulin-dependent diabetes mellitus. J Clin Endocrinol Metab 1993, 77:1072-1077.
    • (1993) J Clin Endocrinol Metab , vol.77 , pp. 1072-1077
    • Ohno, Y.1    Aoki, N.2    Nishimura, A.3
  • 181
    • 84896131810 scopus 로고    scopus 로고
    • Cannabis finds its way into treatment of Crohn's disease
    • Schicho R., Storr M. Cannabis finds its way into treatment of Crohn's disease. Pharmacology 2014, 93(0):1-3.
    • (2014) Pharmacology , vol.93 , pp. 1-3
    • Schicho, R.1    Storr, M.2
  • 182
  • 183
    • 11144355734 scopus 로고    scopus 로고
    • The endogenous cannabinoid system protects against colonic inflammation
    • Massa F., Marsicano G., Hermann H., Cannich A., et al. The endogenous cannabinoid system protects against colonic inflammation. J Clin Invest 2004, 113:1202-1209.
    • (2004) J Clin Invest , vol.113 , pp. 1202-1209
    • Massa, F.1    Marsicano, G.2    Hermann, H.3    Cannich, A.4
  • 184
    • 77954274726 scopus 로고    scopus 로고
    • Mice lacking cannabinoid CB1-, CB2-receptors or both receptors show increased susceptibility to trinitrobenzene sulfonic acid (TNBS)-induced colitis
    • Engel M.A., Kellermann C.A., Burnat G., Hahn E.G., et al. Mice lacking cannabinoid CB1-, CB2-receptors or both receptors show increased susceptibility to trinitrobenzene sulfonic acid (TNBS)-induced colitis. J Physiol Pharmacol 2010, 61:89-97.
    • (2010) J Physiol Pharmacol , vol.61 , pp. 89-97
    • Engel, M.A.1    Kellermann, C.A.2    Burnat, G.3    Hahn, E.G.4
  • 185
    • 70449522049 scopus 로고    scopus 로고
    • Cannabidiol, a safe and non-psychotropic ingredient of the marijuana plant Cannabis sativa, is protective in a murine model of colitis
    • Borrelli F., Aviello G., Romano B., Orlando P., et al. Cannabidiol, a safe and non-psychotropic ingredient of the marijuana plant Cannabis sativa, is protective in a murine model of colitis. J Mol Med (Berl) 2009, 87:1111-1121.
    • (2009) J Mol Med (Berl) , vol.87 , pp. 1111-1121
    • Borrelli, F.1    Aviello, G.2    Romano, B.3    Orlando, P.4
  • 186
    • 84857931127 scopus 로고    scopus 로고
    • Topical and systemic cannabidiol improves trinitrobenzene sulfonic acid colitis in mice
    • Schicho R., Storr M. Topical and systemic cannabidiol improves trinitrobenzene sulfonic acid colitis in mice. Pharmacology 2012, 89:149-155.
    • (2012) Pharmacology , vol.89 , pp. 149-155
    • Schicho, R.1    Storr, M.2
  • 187
    • 77952593814 scopus 로고    scopus 로고
    • The effects of delta-tetrahydrocan-nabinol and cannabidiol alone and in combination on damage, inflammation and in vitro motility disturbances in rat colitis
    • Jamontt J.M., Molleman A., Pertwee R.G., Parsons M.E. The effects of delta-tetrahydrocan-nabinol and cannabidiol alone and in combination on damage, inflammation and in vitro motility disturbances in rat colitis. Br J Pharmacol 2010, 160:712-723.
    • (2010) Br J Pharmacol , vol.160 , pp. 712-723
    • Jamontt, J.M.1    Molleman, A.2    Pertwee, R.G.3    Parsons, M.E.4
  • 188
    • 33745783119 scopus 로고    scopus 로고
    • Agonists of cannabinoid receptor 1 and 2 inhibit experimental colitis induced by oil of mustard and by dextran sulfate sodium
    • Kimball E.S., Schneider C.R., Wallace N.H., Hornby P.J. Agonists of cannabinoid receptor 1 and 2 inhibit experimental colitis induced by oil of mustard and by dextran sulfate sodium. Am J Physiol Gastrointest Liver Physiol 2006, 291:G364-G371.
    • (2006) Am J Physiol Gastrointest Liver Physiol , vol.291 , pp. G364-G371
    • Kimball, E.S.1    Schneider, C.R.2    Wallace, N.H.3    Hornby, P.J.4
  • 189
    • 80051695834 scopus 로고    scopus 로고
    • Increasing endogenous 2-ara-chidonoylglycerol levels counteracts colitis and related systemic inflammation
    • Alhouayek M., Lambert D.M., Delzenne N.M., Cani P.D., et al. Increasing endogenous 2-ara-chidonoylglycerol levels counteracts colitis and related systemic inflammation. FASEB J 2011, 25:2711-2721.
    • (2011) FASEB J , vol.25 , pp. 2711-2721
    • Alhouayek, M.1    Lambert, D.M.2    Delzenne, N.M.3    Cani, P.D.4
  • 191
    • 0037234919 scopus 로고    scopus 로고
    • Cannabinoids for gastrointestinal diseases: potential therapeutic applications
    • Di Carlo G., Izzo A.A. Cannabinoids for gastrointestinal diseases: potential therapeutic applications. Expert Opin Investig Drugs 2003, 12(1):39-49.
    • (2003) Expert Opin Investig Drugs , vol.12 , Issue.1 , pp. 39-49
    • Di Carlo, G.1    Izzo, A.A.2
  • 192
  • 194
    • 23244457833 scopus 로고    scopus 로고
    • Differential expression of cannabinoid receptors in the human colon: cannabinoids promote epithelial wound healing
    • Wright K., Rooney N., Feeney M., Tate J., Robertson D., Welham M., et al. Differential expression of cannabinoid receptors in the human colon: cannabinoids promote epithelial wound healing. Gastroenterology 2005, 129:437-453.
    • (2005) Gastroenterology , vol.129 , pp. 437-453
    • Wright, K.1    Rooney, N.2    Feeney, M.3    Tate, J.4    Robertson, D.5    Welham, M.6
  • 195
    • 84855765207 scopus 로고    scopus 로고
    • Cannabinoid receptor-2 (CB2) agonist ameliorates colitis in IL-10(-/-) mice by attenuating the activation of T cells and promoting their apoptosis
    • Singh U.P., Singh N.P., Singh B., Price R.L., Nagarkatti M., Nagarkatti P.S. Cannabinoid receptor-2 (CB2) agonist ameliorates colitis in IL-10(-/-) mice by attenuating the activation of T cells and promoting their apoptosis. Toxicol Appl Pharmacol. 2012, 258(2):256-267.
    • (2012) Toxicol Appl Pharmacol. , vol.258 , Issue.2 , pp. 256-267
    • Singh, U.P.1    Singh, N.P.2    Singh, B.3    Price, R.L.4    Nagarkatti, M.5    Nagarkatti, P.S.6
  • 196
    • 77649275461 scopus 로고    scopus 로고
    • Cannabinoids and the gut: new developments and emerging concepts
    • Izzo A.A., Sharkey K.A. Cannabinoids and the gut: new developments and emerging concepts. Pharmacol Ther 2010, 126:21-38.
    • (2010) Pharmacol Ther , vol.126 , pp. 21-38
    • Izzo, A.A.1    Sharkey, K.A.2
  • 197
    • 84866926742 scopus 로고    scopus 로고
    • The endocannabinoid system in inflammatory bowel diseases: from pathophysiology to therapeutic opportunity
    • Alhouayek M., Muccioli G.G. The endocannabinoid system in inflammatory bowel diseases: from pathophysiology to therapeutic opportunity. Trends Mol Med 2012, 18:615-625.
    • (2012) Trends Mol Med , vol.18 , pp. 615-625
    • Alhouayek, M.1    Muccioli, G.G.2
  • 198
    • 48249136051 scopus 로고    scopus 로고
    • Emerging role of cannabinoids in gastrointestinal and liver diseases: basic and clinical aspects
    • Izzo A.A., Camilleri M. Emerging role of cannabinoids in gastrointestinal and liver diseases: basic and clinical aspects. Gut 2008, 57:1140-1155.
    • (2008) Gut , vol.57 , pp. 1140-1155
    • Izzo, A.A.1    Camilleri, M.2
  • 199
    • 77956260156 scopus 로고    scopus 로고
    • Naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl) methanone (SAB378), a peripherally restricted cannabinoid CB1/CB2 receptors agonist, inhibits gastrointestinal motility but has no effect on experimental colitis in mice
    • Cluny N.L., Keenan C.M., Duncan M., Fox A., Lutz B., Sharkey K.A. Naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl) methanone (SAB378), a peripherally restricted cannabinoid CB1/CB2 receptors agonist, inhibits gastrointestinal motility but has no effect on experimental colitis in mice. J Pharmacol Exp Ther 2010, 334:973-980.
    • (2010) J Pharmacol Exp Ther , vol.334 , pp. 973-980
    • Cluny, N.L.1    Keenan, C.M.2    Duncan, M.3    Fox, A.4    Lutz, B.5    Sharkey, K.A.6
  • 203
    • 0021877203 scopus 로고
    • Recurrence after surgery in Crohn's disease. relationship to location of disease (clinical pattern) and surgical indication
    • Whelan G., Farmer R.G., Fazio V.W., et al. Recurrence after surgery in Crohn's disease. relationship to location of disease (clinical pattern) and surgical indication. Gastroenterology 1985, 88:1826-1833.
    • (1985) Gastroenterology , vol.88 , pp. 1826-1833
    • Whelan, G.1    Farmer, R.G.2    Fazio, V.W.3
  • 204
    • 80052519916 scopus 로고    scopus 로고
    • Treatment of Crohn's disease with cannabis: an observational study
    • Naftali T., Lev L.B., Yablekovitz D., Half E., Konikoff F.M. Treatment of Crohn's disease with cannabis: an observational study. IMAJ 2011, 13:455-458.
    • (2011) IMAJ , vol.13 , pp. 455-458
    • Naftali, T.1    Lev, L.B.2    Yablekovitz, D.3    Half, E.4    Konikoff, F.M.5
  • 206
    • 81155125103 scopus 로고    scopus 로고
    • Impact of cannabis treatment on the quality of life, weight and clinical disease activity in inflammatory bowel disease patients: a pilot prospective study
    • Lahat A., Lang A., Ben-Horin S. Impact of cannabis treatment on the quality of life, weight and clinical disease activity in inflammatory bowel disease patients: a pilot prospective study. Digestion 2012, 85:1-8.
    • (2012) Digestion , vol.85 , pp. 1-8
    • Lahat, A.1    Lang, A.2    Ben-Horin, S.3
  • 207
    • 84873287705 scopus 로고    scopus 로고
    • Low dose vaporized cannabis significantly improves neuropathic pain
    • Wilsey B., Marcotte T.D., Deutsch R., Gouaux B., Sakai S., Donaghe H. Low dose vaporized cannabis significantly improves neuropathic pain. J Pain 2013 February, 14(2):136-148.
    • (2013) J Pain , vol.14 , Issue.2 , pp. 136-148
    • Wilsey, B.1    Marcotte, T.D.2    Deutsch, R.3    Gouaux, B.4    Sakai, S.5    Donaghe, H.6
  • 208
    • 77950367410 scopus 로고    scopus 로고
    • Recommendations for the pharmacological management of neuropathic pain: an overview and literature update
    • Dworkin R.H., Turk D.C., Walco G.A., Wells C.D., O'Connor A.B., Audette J., et al. Recommendations for the pharmacological management of neuropathic pain: an overview and literature update. Mayo Clin Proc 2010, 85:S3-14.
    • (2010) Mayo Clin Proc , vol.85 , pp. S3-14
    • Dworkin, R.H.1    Turk, D.C.2    Walco, G.A.3    Wells, C.D.4    O'Connor, A.B.5    Audette, J.6
  • 209
    • 70349333074 scopus 로고    scopus 로고
    • Cannabinoids as pharmacotherapies for neuropathic pain: from the bench to the bedside
    • Rahn E.J., Hohmann A.G. Cannabinoids as pharmacotherapies for neuropathic pain: from the bench to the bedside. Neurotherapeutics 2009, 6:713-737.
    • (2009) Neurotherapeutics , vol.6 , pp. 713-737
    • Rahn, E.J.1    Hohmann, A.G.2
  • 210
    • 79959794466 scopus 로고    scopus 로고
    • The need for a Canadian pain strategy
    • Lynch M.E. The need for a Canadian pain strategy. Pain Res Manag 2011, 16:77-80.
    • (2011) Pain Res Manag , vol.16 , pp. 77-80
    • Lynch, M.E.1
  • 211
    • 33645736058 scopus 로고    scopus 로고
    • Suicidality in chronic pain: review of the prevalence, risk factors and psychological links
    • Tang N., Crane C. Suicidality in chronic pain: review of the prevalence, risk factors and psychological links. Psychol Med 2006, 36:575-586.
    • (2006) Psychol Med , vol.36 , pp. 575-586
    • Tang, N.1    Crane, C.2
  • 213
    • 0011205319 scopus 로고    scopus 로고
    • Are cannabinoids an effective and safe treatment option in the management of pain?
    • Campbell F.A., Tramèr M.R., Carroll D., et al. Are cannabinoids an effective and safe treatment option in the management of pain?. BMJ 2001, 323:1-6.
    • (2001) BMJ , vol.323 , pp. 1-6
    • Campbell, F.A.1    Tramèr, M.R.2    Carroll, D.3
  • 214
    • 0033856751 scopus 로고    scopus 로고
    • Ajulemic acid (CT3): a potent analog of the acid metabolites of THC
    • Burstein S.H. Ajulemic acid (CT3): a potent analog of the acid metabolites of THC. Curr Pharm Des 2000, 6:1339-1345.
    • (2000) Curr Pharm Des , vol.6 , pp. 1339-1345
    • Burstein, S.H.1
  • 215
    • 0038745585 scopus 로고    scopus 로고
    • Activation and binding of peroxisome proliferator-activated receptor γ by synthetic cannabinoid ajulemic acid
    • Liu J., Li H., Burstein S.H., et al. Activation and binding of peroxisome proliferator-activated receptor γ by synthetic cannabinoid ajulemic acid. Mol Pharmacol 2003, 63:983-992.
    • (2003) Mol Pharmacol , vol.63 , pp. 983-992
    • Liu, J.1    Li, H.2    Burstein, S.H.3
  • 216
    • 0032511059 scopus 로고    scopus 로고
    • Analgesic effects of 1',1'dimethylheptyl-delta8-THC-11-oic acid (CT3) in mice
    • Burstein S.H., Friderichs E., Kögel B., et al. Analgesic effects of 1',1'dimethylheptyl-delta8-THC-11-oic acid (CT3) in mice. Life Sci 1998, 63:161-168.
    • (1998) Life Sci , vol.63 , pp. 161-168
    • Burstein, S.H.1    Friderichs, E.2    Kögel, B.3
  • 218
    • 33847013770 scopus 로고    scopus 로고
    • Cannabis in painful HIV-associated sensory neuropathy: a randomized placebo-controlled trial
    • Abrams D.I., Jay C.A., Shade S.B., Vizoso H., Reda H., Press S., et al. Cannabis in painful HIV-associated sensory neuropathy: a randomized placebo-controlled trial. Neurology 2007, 68:515-521.
    • (2007) Neurology , vol.68 , pp. 515-521
    • Abrams, D.I.1    Jay, C.A.2    Shade, S.B.3    Vizoso, H.4    Reda, H.5    Press, S.6
  • 221
    • 38449103007 scopus 로고    scopus 로고
    • Dose-dependent effects of smoked cannabis on capsaicin-induced pain and hyperalgesia in healthy volunteers
    • Wallace M., Schulteis G., Atkinson J.H., Wolfson T., Lazzaretto D., Bentley H., et al. Dose-dependent effects of smoked cannabis on capsaicin-induced pain and hyperalgesia in healthy volunteers. Anesthesiology 2007, 107:785-796.
    • (2007) Anesthesiology , vol.107 , pp. 785-796
    • Wallace, M.1    Schulteis, G.2    Atkinson, J.H.3    Wolfson, T.4    Lazzaretto, D.5    Bentley, H.6
  • 222
    • 77958035149 scopus 로고    scopus 로고
    • Smoked cannabis for chronic neuropathic pain: a randomized controlled trial
    • Ware M.A., Wang T., Shapiro S., Robinson A., Ducruet T., Huynh T., et al. Smoked cannabis for chronic neuropathic pain: a randomized controlled trial. CMAJ 2010, 182(14).
    • (2010) CMAJ , vol.182 , Issue.14
    • Ware, M.A.1    Wang, T.2    Shapiro, S.3    Robinson, A.4    Ducruet, T.5    Huynh, T.6
  • 223
    • 0024534999 scopus 로고
    • Fibromyalgia: the clinical syndrome
    • February
    • Wolfe F. Fibromyalgia: the clinical syndrome. Rheum Dis Clin North Am February 1989, 15(1):1-18.
    • (1989) Rheum Dis Clin North Am , vol.15 , Issue.1 , pp. 1-18
    • Wolfe, F.1
  • 224
    • 84963606505 scopus 로고    scopus 로고
    • Common and unique associated factors for medically unexplained chronic widespread pain and chronic fatigue
    • McBeth J., Tomenson B., Chew-Graham C.A., Macfarlane G.J., Jackson J., Littlewood A., et al. Common and unique associated factors for medically unexplained chronic widespread pain and chronic fatigue. J Psychosom Res 2011, 79(6):484-491.
    • (2011) J Psychosom Res , vol.79 , Issue.6 , pp. 484-491
    • McBeth, J.1    Tomenson, B.2    Chew-Graham, C.A.3    Macfarlane, G.J.4    Jackson, J.5    Littlewood, A.6
  • 225
    • 80053571291 scopus 로고    scopus 로고
    • Unraveling the complexities of cannabinoid receptor 2 (CB2) immune regulation in health and disease
    • 5Z, Basu S., Dittel B.H. Unraveling the complexities of cannabinoid receptor 2 (CB2) immune regulation in health and disease. Immunologic Research 2011, 51(1):26-38.
    • (2011) Immunologic Research , vol.51 , Issue.1 , pp. 26-38
    • 5Z1    Basu, S.2    Dittel, B.H.3
  • 226
    • 0030096650 scopus 로고    scopus 로고
    • Problems with myofascial pain syndrome and fibromyalgia syndrome
    • Bohr T. Problems with myofascial pain syndrome and fibromyalgia syndrome. Neurology 1996, 46(3):593-597.
    • (1996) Neurology , vol.46 , Issue.3 , pp. 593-597
    • Bohr, T.1
  • 227
    • 0031032872 scopus 로고    scopus 로고
    • SR 141716 A, a cannabinoid receptor antagonist, produces hyperalgesia in untreated mice
    • Richardson J.D., Aanonsen L., Hargreaves K.M. SR 141716 A, a cannabinoid receptor antagonist, produces hyperalgesia in untreated mice. Eur J Pharmacol 1997, 319(2-3):R3-R4.
    • (1997) Eur J Pharmacol , vol.319 , Issue.2-3 , pp. R3-R4
    • Richardson, J.D.1    Aanonsen, L.2    Hargreaves, K.M.3
  • 228
    • 79955385056 scopus 로고    scopus 로고
    • Cannabis use in patients with fibromyalgia: effect on symptoms relief and health-related quality of life
    • Fiz V.J., Duran M., Capella D., Carbonell J., Farre M. Cannabis use in patients with fibromyalgia: effect on symptoms relief and health-related quality of life. PLoS ONE 2011, 6(4):18440.
    • (2011) PLoS ONE , vol.6 , Issue.4 , pp. 18440
    • Fiz, V.J.1    Duran, M.2    Capella, D.3    Carbonell, J.4    Farre, M.5
  • 229
    • 76249123626 scopus 로고    scopus 로고
    • The effects of nabilone on sleep in fibromyalgia: results of a randomized controlled trial
    • Ware M.A., Fitzcharles M.A., Joseph L., Shir Y. The effects of nabilone on sleep in fibromyalgia: results of a randomized controlled trial. Anesth Analg 2010 Feb 1, 110(2):604-610.
    • (2010) Anesth Analg , vol.110 , Issue.2 , pp. 604-610
    • Ware, M.A.1    Fitzcharles, M.A.2    Joseph, L.3    Shir, Y.4
  • 230
    • 46049119745 scopus 로고    scopus 로고
    • Adverse effects of medical cannabinoids: a systematic review
    • Wang T., Collet J.-P., Shapiro S., Ware M.A. Adverse effects of medical cannabinoids: a systematic review. Can Med Assoc J 2008, 178(13):1669-1678.
    • (2008) Can Med Assoc J , vol.178 , Issue.13 , pp. 1669-1678
    • Wang, T.1    Collet, J.-P.2    Shapiro, S.3    Ware, M.A.4
  • 231
    • 0016425051 scopus 로고
    • Analgesic effect of delta-9-tetrahydrocannabinol
    • Noyes R., Brunk S.F., Baram D.A., Canter A. Analgesic effect of delta-9-tetrahydrocannabinol. J Clin Pharmacol 1975, 15(2-3):139-143.
    • (1975) J Clin Pharmacol , vol.15 , Issue.2-3 , pp. 139-143
    • Noyes, R.1    Brunk, S.F.2    Baram, D.A.3    Canter, A.4
  • 232
    • 0016527783 scopus 로고
    • The analgesic properties of delta-9-tetrahydrocannabinol and codeine
    • Noyes R., Brunk S.F., Avery D.H., Canter A. The analgesic properties of delta-9-tetrahydrocannabinol and codeine. Clin Pharmacol Ther 1975, 18:84-89.
    • (1975) Clin Pharmacol Ther , vol.18 , pp. 84-89
    • Noyes, R.1    Brunk, S.F.2    Avery, D.H.3    Canter, A.4
  • 233
    • 0019605641 scopus 로고
    • Evaluation of intramuscular levonantradol and plecebo in acute postoperative pain
    • Jain A.K., Ryan J.R., McMahon F.G., Smith G. Evaluation of intramuscular levonantradol and plecebo in acute postoperative pain. J Clin Pharmacol 1981, 21:320S-3236.
    • (1981) J Clin Pharmacol , vol.21 , pp. 320S-3236
    • Jain, A.K.1    Ryan, J.R.2    McMahon, F.G.3    Smith, G.4
  • 234
    • 0019460943 scopus 로고
    • A prospective evaluation of delta-9-tetrahydrocannabinol as an antiemetic in patients receiving adriamycin and cytoxan chemotherapy
    • Chang A.E., Shiling D.J., Stillman R.C., et al. A prospective evaluation of delta-9-tetrahydrocannabinol as an antiemetic in patients receiving adriamycin and cytoxan chemotherapy. Cancer 1981, 47:1746-1751.
    • (1981) Cancer , vol.47 , pp. 1746-1751
    • Chang, A.E.1    Shiling, D.J.2    Stillman, R.C.3
  • 235
    • 0023803116 scopus 로고
    • Inhalation marijuana as an antiemetic for cancer chemotherapy
    • Vinciguerra V., Moore T., Brennan E. Inhalation marijuana as an antiemetic for cancer chemotherapy. N Y State J Med 1988, 88(10):525-527.
    • (1988) N Y State J Med , vol.88 , Issue.10 , pp. 525-527
    • Vinciguerra, V.1    Moore, T.2    Brennan, E.3
  • 236
    • 0018969807 scopus 로고
    • Antiemetic effect of tetrahydrocannabinol. Compared with placebo and prochlorperazine in chemotherapy-associated nausea and emesis
    • Orr L.E., McKernan J.F., Bloome B. Antiemetic effect of tetrahydrocannabinol. Compared with placebo and prochlorperazine in chemotherapy-associated nausea and emesis. Arch Intern Med 1980, 140:1431-1433.
    • (1980) Arch Intern Med , vol.140 , pp. 1431-1433
    • Orr, L.E.1    McKernan, J.F.2    Bloome, B.3
  • 237
    • 0018922982 scopus 로고
    • Antiemetics in patients receiving chemotherapy for cancer: a randomized comparison of delta-9-tetrahydrocannabinol and prochlorperazine
    • Sallan S.E., Cronin C., Zelen M., Zinberg N.E. Antiemetics in patients receiving chemotherapy for cancer: a randomized comparison of delta-9-tetrahydrocannabinol and prochlorperazine. N Engl J Med 1980, 302(3):135-138.
    • (1980) N Engl J Med , vol.302 , Issue.3 , pp. 135-138
    • Sallan, S.E.1    Cronin, C.2    Zelen, M.3    Zinberg, N.E.4
  • 238
    • 0018899177 scopus 로고
    • Double-blind comparison of the antiemetic effects of nabilone and prochlorperazine on chemotherapy-induced emesis
    • Steele N., Gralla R.J., Braun D.W., Young C.W. Double-blind comparison of the antiemetic effects of nabilone and prochlorperazine on chemotherapy-induced emesis. Cancer Treat Rep 1980, 64(2-3):219-224.
    • (1980) Cancer Treat Rep , vol.64 , Issue.2-3 , pp. 219-224
    • Steele, N.1    Gralla, R.J.2    Braun, D.W.3    Young, C.W.4
  • 240
    • 0026000974 scopus 로고
    • Management of anorexia-cachexia associated with cancer and HIV infection
    • Gorter R. Management of anorexia-cachexia associated with cancer and HIV infection. Oncol Suppl 1991, 5:13-17.
    • (1991) Oncol Suppl , vol.5 , pp. 13-17
    • Gorter, R.1
  • 241
    • 0027200985 scopus 로고
    • Effect of dronabinol on nutritional status in HIV infection
    • Struwe M., Kaempfer S.H., Geiger C.J., et al. Effect of dronabinol on nutritional status in HIV infection. Ann Pharmacother 1993, 27(7-8):827-831.
    • (1993) Ann Pharmacother , vol.27 , Issue.7-8 , pp. 827-831
    • Struwe, M.1    Kaempfer, S.H.2    Geiger, C.J.3
  • 242
    • 0028935579 scopus 로고
    • Dronabinol as a treatment for anorexia associated with weight loss in patients with AIDS
    • Beal J.E., Olson R.L.L., Morales J.O., et al. Dronabinol as a treatment for anorexia associated with weight loss in patients with AIDS. J Pain Symptom Manage 1995, 10:89-97.
    • (1995) J Pain Symptom Manage , vol.10 , pp. 89-97
    • Beal, J.E.1    Olson, R.L.L.2    Morales, J.O.3
  • 243
    • 8544278893 scopus 로고    scopus 로고
    • Long-term efficacy and safety of dronabinol for acquired immunodeficiency syndrome-associated anorexia
    • Beal J.E., Olson R., Lefkowitz L., et al. Long-term efficacy and safety of dronabinol for acquired immunodeficiency syndrome-associated anorexia. J Pain Symptom Manage 1997, 14:7-14.
    • (1997) J Pain Symptom Manage , vol.14 , pp. 7-14
    • Beal, J.E.1    Olson, R.2    Lefkowitz, L.3
  • 244
    • 84963763745 scopus 로고    scopus 로고
    • The medical value of marijuana and related substances. Marijuana and Medicine
    • National Academy Press
    • National Academy of Science, Institute of Medicine The medical value of marijuana and related substances. Marijuana and Medicine. Assessing the Science Base 1999, National Academy Press.
    • (1999) Assessing the Science Base
  • 246
    • 4344585483 scopus 로고    scopus 로고
    • An open-label pilot study of cannabis-based extracts for bladder dysfunction in advanced multiple sclerosis
    • Brady C.M., DasGupta R., Dalton C., Wiseman O.J., Berkley K.J., Fowler C.J. An open-label pilot study of cannabis-based extracts for bladder dysfunction in advanced multiple sclerosis. Mult Scler 2004, 10(4):425-433.
    • (2004) Mult Scler , vol.10 , Issue.4 , pp. 425-433
    • Brady, C.M.1    DasGupta, R.2    Dalton, C.3    Wiseman, O.J.4    Berkley, K.J.5    Fowler, C.J.6
  • 247
    • 3142737160 scopus 로고    scopus 로고
    • Cannabinoids cool the intestine
    • Kunos G., Pacher P. Cannabinoids cool the intestine. Nat Med 2004, 10(7):678-679.
    • (2004) Nat Med , vol.10 , Issue.7 , pp. 678-679
    • Kunos, G.1    Pacher, P.2
  • 249
    • 0035831179 scopus 로고    scopus 로고
    • Cannabinoid CB1 receptor upregulation in a rat model of chronic neuropathic pain
    • Siegling A., Hofmann H.A., Denzer D. Cannabinoid CB1 receptor upregulation in a rat model of chronic neuropathic pain. Eur J Pharmacol 2001, 415:5-7.
    • (2001) Eur J Pharmacol , vol.415 , pp. 5-7
    • Siegling, A.1    Hofmann, H.A.2    Denzer, D.3
  • 251
    • 0034883101 scopus 로고    scopus 로고
    • Medicinal use of cannabis: history and current status
    • Kalant H. Medicinal use of cannabis: history and current status. Pain Res Manag 2001, 6:80-91.
    • (2001) Pain Res Manag , vol.6 , pp. 80-91
    • Kalant, H.1
  • 254
    • 61649089261 scopus 로고    scopus 로고
    • Central side-effects of therapies based on CB1 cannabinoid receptor agonists and antagonists: focus on anxiety and depression
    • Moreira F.A., Grieb M., Lutz B. Central side-effects of therapies based on CB1 cannabinoid receptor agonists and antagonists: focus on anxiety and depression. Best Pract Res Clin Endocrinol Metab 2009, 23:133-144.
    • (2009) Best Pract Res Clin Endocrinol Metab , vol.23 , pp. 133-144
    • Moreira, F.A.1    Grieb, M.2    Lutz, B.3
  • 255
    • 0022481918 scopus 로고
    • Cannabis psychosis
    • Ghodse A.H. Cannabis psychosis. Br J Addict 1986, 81:473-478.
    • (1986) Br J Addict , vol.81 , pp. 473-478
    • Ghodse, A.H.1
  • 256
    • 57049112166 scopus 로고    scopus 로고
    • Cannabis use and the risk of developing a psychotic disorder
    • Hall W., Degenhardt L. Cannabis use and the risk of developing a psychotic disorder. World Psychiatry 2008, 7:68-71.
    • (2008) World Psychiatry , vol.7 , pp. 68-71
    • Hall, W.1    Degenhardt, L.2
  • 257
    • 4243057291 scopus 로고    scopus 로고
    • Marijuana-induced transient global amnesia
    • Shukla P.C., Moore U.B. Marijuana-induced transient global amnesia. South Med J 2004, 97:782-784.
    • (2004) South Med J , vol.97 , pp. 782-784
    • Shukla, P.C.1    Moore, U.B.2
  • 258
    • 84904513857 scopus 로고    scopus 로고
    • Long-term effects of cannabis on brain structure
    • Battistella G., Fornari E., Annoni J.-M., et al. Long-term effects of cannabis on brain structure. Neuropsychopharmacology 2014, 39(9):2041-2048.
    • (2014) Neuropsychopharmacology , vol.39 , Issue.9 , pp. 2041-2048
    • Battistella, G.1    Fornari, E.2    Annoni, J.-M.3
  • 261
    • 84949008811 scopus 로고    scopus 로고
    • Evaluating the relationship between cannabis use and IQ in youth and young adults at clinical high risk of psychosis
    • Dec 30
    • Buchy L., Seidman L.J., Cadenhead K.S., Cannon T.D., Cornblatt B.A., McGlashan T.H., et al. Evaluating the relationship between cannabis use and IQ in youth and young adults at clinical high risk of psychosis. Psychiatry Res Dec 30, 2015, 230(3):878-884.
    • (2015) Psychiatry Res , vol.230 , Issue.3 , pp. 878-884
    • Buchy, L.1    Seidman, L.J.2    Cadenhead, K.S.3    Cannon, T.D.4    Cornblatt, B.A.5    McGlashan, T.H.6
  • 262
    • 27944440482 scopus 로고    scopus 로고
    • Cannabis and endocannabinoid modulators: therapeutic promises and challenges
    • Grant I., Cahn B.R. Cannabis and endocannabinoid modulators: therapeutic promises and challenges. Clin Neurosci Res 2005, 5(2-4):185-199.
    • (2005) Clin Neurosci Res , vol.5 , Issue.2-4 , pp. 185-199
    • Grant, I.1    Cahn, B.R.2
  • 263
    • 8444244202 scopus 로고    scopus 로고
    • Effect of cannabinoid ingestion (in the form of bhang) on the immune system of high school and university students
    • El-Gohary M., Eid M.A. Effect of cannabinoid ingestion (in the form of bhang) on the immune system of high school and university students. Hum Exp Toxicol 2004, 23:149-156.
    • (2004) Hum Exp Toxicol , vol.23 , pp. 149-156
    • El-Gohary, M.1    Eid, M.A.2
  • 264
    • 46049102056 scopus 로고    scopus 로고
    • The adverse effects of cannabinoids: implications for use of medical marijuana
    • Degenhardt L., Hall W.D. The adverse effects of cannabinoids: implications for use of medical marijuana. CMAJ 2008, 178:1685-1686.
    • (2008) CMAJ , vol.178 , pp. 1685-1686
    • Degenhardt, L.1    Hall, W.D.2
  • 265
    • 39149123169 scopus 로고    scopus 로고
    • Recreational drug toxicity
    • Hill S., Thomas S.H. Recreational drug toxicity. Clin Med 2008, 8:99-103.
    • (2008) Clin Med , vol.8 , pp. 99-103
    • Hill, S.1    Thomas, S.H.2
  • 266
    • 42249114663 scopus 로고    scopus 로고
    • Long lasting consequences of cannabis exposure in adolescence
    • Rubino T., Parolaro D. Long lasting consequences of cannabis exposure in adolescence. Mol Cell Endocrinol 2008, 286:S108-S113.
    • (2008) Mol Cell Endocrinol , vol.286 , pp. S108-S113
    • Rubino, T.1    Parolaro, D.2
  • 267
    • 23844510064 scopus 로고    scopus 로고
    • Smoked marijuana as a cause of lung injury
    • Tashkin D.P. Smoked marijuana as a cause of lung injury. Monaldi Arch Chest Dis 2005, 63:93-100.
    • (2005) Monaldi Arch Chest Dis , vol.63 , pp. 93-100
    • Tashkin, D.P.1
  • 268
    • 0032520649 scopus 로고    scopus 로고
    • Regulation of the cAMP cascade, gene expression and immune function by cannabinoid receptors
    • Kaminski N.E. Regulation of the cAMP cascade, gene expression and immune function by cannabinoid receptors. J Neuroimmunol 1998, 83:124-132.
    • (1998) J Neuroimmunol , vol.83 , pp. 124-132
    • Kaminski, N.E.1
  • 269
    • 0021824944 scopus 로고
    • Health consequences of acute and chronic marihuana use
    • Maykut M.O. Health consequences of acute and chronic marihuana use. Prog Neuropsychopharmacol Biol Psychiatry 1985, 9:209-238.
    • (1985) Prog Neuropsychopharmacol Biol Psychiatry , vol.9 , pp. 209-238
    • Maykut, M.O.1


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