Cannabinoids down-regulate PI3K/Akt and Erk signalling pathways and activate proapoptotic function of Bad protein

Cellular Signalling

Volumn 17, Issue 1, 2005, Pages 25-37

  Ellert Miklaszewska, Aleksandra ^a   Kaminska, Bozena ^b   Konarska, Liliana ^a  

^a MEDICAL UNIVERSITY OF WARSAW   (Poland)

^b NENCKI INSTITUTE OF EXPERIMENTAL BIOLOGY   (Poland)

Author keywords

Apoptosis; Bad; Cannabinoids; Glioma; Mitochondria

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; 2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; CANNABINOID; CASPASE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BAD; PROTEIN BCL 2; PROTEIN KINASE B;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL MEMBRANE DEPOLARIZATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; EXPOSURE; GENE CONTROL; GLIOMA CELL; HYPOTHESIS; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; SURVIVAL; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; APOPTOSIS; BCL-ASSOCIATED DEATH PROTEIN; CANNABINOIDS; CARRIER PROTEINS; CELL CYCLE; CELL LINE, TUMOR; CELL SURVIVAL; GENE EXPRESSION REGULATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLIOMA; KINETICS; MAP KINASE SIGNALING SYSTEM; MORPHOLINES; NAPHTHALENES; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RATS;

EID: 4644226099     PISSN: 08986568     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellsig.2004.05.011     Document Type: Article

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