Differential expression of the CB2 cannabinoid receptor by rodent macrophages and macrophage-like cells in relation to cell activation

International Immunopharmacology

Volumn 2, Issue 1, 2002, Pages 69-82

  Carlisle, S J ^a   Marciano Cabral, F ^a   Staab, A ^a   Ludwick, C ^a   Cabral, G A ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cannabinoid receptors; CB1; CB2; Macrophage activation; Murine macrophage like cells; Murine peritoneal macrophages; Neonatal rat microglia

Indexed keywords

CANNABINOID; CANNABINOID 2 RECEPTOR; CANNABINOID RECEPTOR; CANNABINOID RECEPTOR CB2, RAT; DRUG RECEPTOR; DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS; MESSENGER RNA; BACTERIUM LIPOPOLYSACCHARIDE; CANNABINOID 1 RECEPTOR; GAMMA INTERFERON; THIOGLYCOLIC ACID;

ANIMAL; ARTICLE; BIOSYNTHESIS; BRAIN CORTEX; CELL CULTURE; CELL LINE; CYTOLOGY; DRUG EFFECT; IMMUNOLOGY; INFLAMMATION; MACROPHAGE; MACROPHAGE ACTIVATION; METABOLISM; MICROGLIA; MOUSE; NEWBORN; NUCLEASE PROTECTION ASSAY; PATHOLOGY; PERITONEUM MACROPHAGE; PHYSIOLOGY; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCANNING ELECTRON MICROSCOPY; SPRAGUE DAWLEY RAT; WESTERN BLOTTING; ANIMAL CELL; BRAIN CELL; CELL LINEAGE; CONTROLLED STUDY; IMMUNOMODULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; SPECIES DIFFERENCE;

ANIMALS; ANIMALS, NEWBORN; BLOTTING, WESTERN; CANNABINOIDS; CELL LINE; CELLS, CULTURED; CEREBRAL CORTEX; INDICATORS AND REAGENTS; INFLAMMATION; MACROPHAGE ACTIVATION; MACROPHAGES; MACROPHAGES, PERITONEAL; MICE; MICROGLIA; MICROSCOPY, ELECTRON, SCANNING; NUCLEASE PROTECTION ASSAYS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, CANNABINOID, CB2; RECEPTORS, CANNABINOID; RECEPTORS, DRUG; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 0035191240     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1567-5769(01)00147-3     Document Type: Article

References (41)

1. Drugs and immunity: Cannabinoids and their role in decreased resistance to infectious disease
2. Cannabinoid receptors and the cytokine network
3. 1) mediates inhibition of nitric oxide release from activated rat microglial cells
4. Cannabinoid inhibition of the processing of intact lysozyme by macrophages: Evidence for CB2 receptor participation
5. Structure of a cannabinoid receptor and functional expression of the cloned cDNA
6. Molecular cloning of a human cannabinoid receptor which is also expressed in testis
7. Expression of central and peripheral cannabinoid receptors in human immune tissues and leukocyte subpopulations
8. Molecular characterization of a peripheral receptor for cannabinoids
9. Expression of the CB1 and CB2 receptor messenger RNAs during embryonic development in the rat
10. Expression of CB2 cannabinoid receptor mRNA in adult rat retina
11. Involvement of Gi in the inhibition of adenylate cyclase by cannabimimetic drugs
12. Identification of a functionally relevant cannabinoid receptor on mouse spleen cells that is involved in cannabinoid-mediated immune modulation
13. 2 receptors
14. 2: A characterization of expression and adenylate cyclase modulation within the immune system
15. The endogenous cannabinoid anandamide potentiates interleukin-6 production by astrocytes infected with Theiler's murine encephalomyelitis virus by a receptor-mediated pathway
16. Oxidative stress produced by marijuana smoke. An adverse effect enhanced by cannabinoids
17. Delta 9-tetrahydrocannabinol modulates antigen processing by macrophages
18. Tetrahydrocannabinol inhibition of macrophage nitric oxide production
19. 1 cannabinoid receptor in macrophage-like cells from brain tissue: Immunochemical characterization by fusion protein antibodies
20. Cannabinoids inhibit LPS-inducible cytokine mRNA expression in rat microglial cells
21. Differentiation and activation of macrophages and microglia in the nervous system
22. The origin and nature of ramified and amoeboid microglia: A historical review and current concepts
23. Amoeboid and ramified microglia: Their interrelationship and response to brain injury
24. IL-1 of the central nervous system is produced by ameboid microglia
25. Detection of interleukin-1 and interleukin-6 in adult rat brain following mechanical injury by in vivo microdialysis: Evidence of a role for microglia in cytokine production
26. Production of tumor necrosis factor-alpha by microglia and astrocytes in culture
27. Mechanisms of target recognition and destruction in macrophage-mediated cytotoxicity
28. Effects of bacterial lipopolysaccharide on protein synthesis in murine peritoneal macrophages: Relationship to activation for macrophage tumoricidal function
29. Biology of cultured nerve and muscle
30. Monoclonal antibodies specific for glial fibrillary acidic (GFA) protein and for each of the neurofilament triplet polypeptides
31. 2 cannabinoid receptor
32. Cannabinoid receptor localization in brain
33. Immunohistochemical localization of the neural cannabinoid receptor in rat brain
34. 1 receptors on rat neuronal cell cultures: Binding and functional studies using the selective receptor antagonist SR 141716A
35. Attenuation of inducible nitric oxide synthase gene expression by Δ9-tetrahydrocannabinol is mediated through the inhibition of nuclear factor-κB/Rel activation
36. Cannabinoid receptor proteins are increased in a Jurkat human T-cell line after mitogen activation
37. 2 peripheral cannabinoid receptors during B-cell differentiation
38. Differential expression of the melatonin receptor in human monocytes
39. Transcription factor nuclear κB regulates the inducible expression of the human B1 receptor gene in inflammation
40. Regulation of CCR2 chemokine receptor mRNA stability
41. High level expression of the human CB2 cannabinoid receptor using a baculovirus system