-
1
-
-
17144462251
-
Therapeutic action of cannabinoids in a murine model of multiple sclerosis
-
Arevalo-Martin A, Vela JM, Molina-Holgado E, Borrell J, Guaza C (2003) Therapeutic action of cannabinoids in a murine model of multiple sclerosis. J Neurosci 23:2511-2516
-
(2003)
J Neurosci
, vol.23
, pp. 2511-2516
-
-
Arevalo-Martin, A.1
Vela, J.M.2
Molina-Holgado, E.3
Borrell, J.4
Guaza, C.5
-
2
-
-
0034594905
-
Cannabinoids control spasticity and tremor in a multiple sclerosis model
-
Baker D, Pryce G, Croxford JL, Brown P, Pertwee RG, Huffman JW, Layward L (2000) Cannabinoids control spasticity and tremor in a multiple sclerosis model. Nature 404:84-87
-
(2000)
Nature
, vol.404
, pp. 84-87
-
-
Baker, D.1
Pryce, G.2
Croxford, J.L.3
Brown, P.4
Pertwee, R.G.5
Huffman, J.W.6
Layward, L.7
-
3
-
-
0035256557
-
Endocannabinoids control spasticity in a multiple sclerosis model
-
Baker D, Pryce G, Croxford JL, Brown P, Pertwee RG, Makriyannis A, Khanolkar A, Layward L, Fezza F, Bisogno T, Di Marzo V (2001) Endocannabinoids control spasticity in a multiple sclerosis model. FASEB J 15:300-302
-
(2001)
FASEB J
, vol.15
, pp. 300-302
-
-
Baker, D.1
Pryce, G.2
Croxford, J.L.3
Brown, P.4
Pertwee, R.G.5
Makriyannis, A.6
Khanolkar, A.7
Layward, L.8
Fezza, F.9
Bisogno, T.10
Di Marzo, V.11
-
6
-
-
0034751335
-
Molecular targets for cannabidiol and its synthetic analogues: Effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide
-
Bisogno T, Hanus L, De Petrocellis L, Tchilibon S, Ponde DE, Brandi I, Moriello AS, Davis JB, Mechoulam R, Di Marzo V (2001) Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide. Br J Pharmacol 134:845-852
-
(2001)
Br J Pharmacol
, vol.134
, pp. 845-852
-
-
Bisogno, T.1
Hanus, L.2
De Petrocellis, L.3
Tchilibon, S.4
Ponde, D.E.5
Brandi, I.6
Moriello, A.S.7
Davis, J.B.8
Mechoulam, R.9
Di Marzo, V.10
-
7
-
-
10744229235
-
Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain
-
Bisogno T, Howell F, Williams G, Minassi A, Cascio MG, Ligresti A, Matias I, Schiano-Moriello A, Paul P, Williams EJ, Gangadharan U, Hobbs C, Di Marzo V, Doherty P (2003) Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain. J Cell Biol 163:463-468
-
(2003)
J Cell Biol
, vol.163
, pp. 463-468
-
-
Bisogno, T.1
Howell, F.2
Williams, G.3
Minassi, A.4
Cascio, M.G.5
Ligresti, A.6
Matias, I.7
Schiano-Moriello, A.8
Paul, P.9
Williams, E.J.10
Gangadharan, U.11
Hobbs, C.12
Di Marzo, V.13
Doherty, P.14
-
8
-
-
0022485445
-
In vitro and in vivo suppressive effects of delta-9-tetrahydrocannabinol on interferon production by murine spleen cells
-
Blanchard DK, Newton C, Klein TW, Stewart WE III, Friedman H (1986) In vitro and in vivo suppressive effects of delta-9-tetrahydrocannabinol on interferon production by murine spleen cells. Int J Immunopharmacol 8:819-824
-
(1986)
Int J Immunopharmacol
, vol.8
, pp. 819-824
-
-
Blanchard, D.K.1
Newton, C.2
Klein, T.W.3
Stewart III, W.E.4
Friedman, H.5
-
9
-
-
0027215426
-
Cannabinoid-receptor expression in human leukocytes
-
Bouaboula M, Rinaldi M, Carayon P, Carillon C, Delpech B, Shire D, LeFur G, Casellas P (1993) Cannabinoid-receptor expression in human leukocytes. Eur J Biochem 214:173-180
-
(1993)
Eur J Biochem
, vol.214
, pp. 173-180
-
-
Bouaboula, M.1
Rinaldi, M.2
Carayon, P.3
Carillon, C.4
Delpech, B.5
Shire, D.6
LeFur, G.7
Casellas, P.8
-
10
-
-
4344585483
-
An open-label pilot study of cannabis-based extracts for bladder dysfunction in advanced multiple sclerosis
-
Brady CM, DasGupta R, Dalton C, Wiseman OJ, Berkley KJ, Fowler CJ (2004) An open-label pilot study of cannabis-based extracts for bladder dysfunction in advanced multiple sclerosis. Mult Scler 10:425-433
-
(2004)
Mult Scler
, vol.10
, pp. 425-433
-
-
Brady, C.M.1
DasGupta, R.2
Dalton, C.3
Wiseman, O.J.4
Berkley, K.J.5
Fowler, C.J.6
-
11
-
-
0034948614
-
Evidence for a new G protein-coupled cannabinoid receptor in mouse brain
-
Breivogel CS, Griffin G, Di Marzo V, Martin BR (2001) Evidence for a new G protein-coupled cannabinoid receptor in mouse brain. Mol Pharmacol 60:155-163
-
(2001)
Mol Pharmacol
, vol.60
, pp. 155-163
-
-
Breivogel, C.S.1
Griffin, G.2
Di Marzo, V.3
Martin, B.R.4
-
12
-
-
0034685707
-
Immunomodulation by cannabinoids is absent in mice deficient for the cannabinoid CB2 receptor
-
Buckley NE, McCoy KL, Mezey E, Bonner T, Zimmer A, Felder CC, Glass M, Zimmer A (2000) Immunomodulation by cannabinoids is absent in mice deficient for the cannabinoid CB2 receptor. Eur J Pharmacol 396:141-149
-
(2000)
Eur J Pharmacol
, vol.396
, pp. 141-149
-
-
Buckley, N.E.1
McCoy, K.L.2
Mezey, E.3
Bonner, T.4
Zimmer, A.5
Felder, C.C.6
Glass, M.7
Zimmer, A.8
-
14
-
-
0027168261
-
Delta-9-tetrahydrocannabinol inhibits cell contact-dependent cytotoxicity of Bacillus Calmette-Guerin-activated macrophages
-
Burnette-Curley D, Marciano-Cabral F, Fischer-Stenger K, Cabral GA (1993) Delta-9-tetrahydrocannabinol inhibits cell contact-dependent cytotoxicity of Bacillus Calmette-Guerin-activated macrophages. Int J Immunopharmacol 15:371-382
-
(1993)
Int J Immunopharmacol
, vol.15
, pp. 371-382
-
-
Burnette-Curley, D.1
Marciano-Cabral, F.2
Fischer-Stenger, K.3
Cabral, G.A.4
-
15
-
-
0026671288
-
Synthetic nonpsychotropic cannabinoids with potent antiinflammatory, analgesic, and leukocyte antiadhesion activities
-
Burstein SH, Audette CA, Breuer A, Devane WA, Colodner S, Doyle SA, Mechoulam R (1992) Synthetic nonpsychotropic cannabinoids with potent antiinflammatory, analgesic, and leukocyte antiadhesion activities. J Med Chem 35:3135-3141
-
(1992)
J Med Chem
, vol.35
, pp. 3135-3141
-
-
Burstein, S.H.1
Audette, C.A.2
Breuer, A.3
Devane, W.A.4
Colodner, S.5
Doyle, S.A.6
Mechoulam, R.7
-
16
-
-
3042701554
-
Ajulemic acid: A novel cannabinoid produces analgesia without a "high"
-
Burstein SH, Karst M, Schneider U, Zurier RB (2004) Ajulemic acid: a novel cannabinoid produces analgesia without a "high". Life Sci 75:1513-1522
-
(2004)
Life Sci
, vol.75
, pp. 1513-1522
-
-
Burstein, S.H.1
Karst, M.2
Schneider, U.3
Zurier, R.B.4
-
17
-
-
0024563469
-
Delta-9-tetrahydrocannabinol inhibits macrophage protein expression in response to bacterial immunomodulators
-
Cabral GA, Mishkin EM (1989) Delta-9-tetrahydrocannabinol inhibits macrophage protein expression in response to bacterial immunomodulators. J Toxicol Environ Health 26:175-182
-
(1989)
J Toxicol Environ Health
, vol.26
, pp. 175-182
-
-
Cabral, G.A.1
Mishkin, E.M.2
-
18
-
-
0026503706
-
9-Tetrahydrocannabinol suppresses macrophage extrinsic antiherpesvirus activity
-
9-Tetrahydrocannabinol suppresses macrophage extrinsic antiherpesvirus activity. Proc Soc Exp Biol Med 199:255-263
-
(1992)
Proc Soc Exp Biol Med
, vol.199
, pp. 255-263
-
-
Cabral, G.A.1
Vasquez, R.2
-
19
-
-
0344505201
-
Drugs and immunity: Cannabinoids and their role in decreased resistance to infectious diseases
-
Cabral G, Dove Pettit D (1998) Drugs and immunity: cannabinoids and their role in decreased resistance to infectious diseases. J Neuroimmunol 83:116-123
-
(1998)
J Neuroimmunol
, vol.83
, pp. 116-123
-
-
Cabral, G.1
Dove Pettit, D.2
-
20
-
-
1642493025
-
Cannabinoid-mediated exacerbation of brain infection by opportunistic amebae
-
Cabral GA, Marciano-Cabral F (2004) Cannabinoid-mediated exacerbation of brain infection by opportunistic amebae. J Neuroimmunol 147:127-130
-
(2004)
J Neuroimmunol
, vol.147
, pp. 127-130
-
-
Cabral, G.A.1
Marciano-Cabral, F.2
-
21
-
-
84859047666
-
Effects on the immune system
-
R Pertwee (ed) Springer-Verlag, Heidelberg
-
Cabral GA, Staab A (2005) Effects on the immune system. In: R Pertwee (ed) Handbook of Experimental Pharmacology, Springer-Verlag, Heidelberg, pp 385-423.
-
(2005)
Handbook of Experimental Pharmacology
, pp. 385-423
-
-
Cabral, G.A.1
Staab, A.2
-
22
-
-
0022618369
-
9-Tetrahydrocannabinol decreases alpha/beta interferon response to herpes simplex virus type 2 in the B6C3F1 mouse
-
9- Tetrahydrocannabinol decreases alpha/beta interferon response to herpes simplex virus type 2 in the B6C3F1 mouse. Proc Soc Exp Biol Med 181:305-311
-
(1986)
Proc Soc Exp Biol Med
, vol.181
, pp. 305-311
-
-
Cabral, G.A.1
Lockmuller, J.C.2
Mishkin, E.M.3
-
23
-
-
0029058904
-
Anandamide inhibits macrophage-mediated killing of tumor necrosis factor-sensitive cells
-
Cabral GA, Toney DM, Fischer-Stenger K, Harrison MP, Marciano-Cabral F (1995) Anandamide inhibits macrophage-mediated killing of tumor necrosis factor-sensitive cells. Life Sci 56:2065-2072
-
(1995)
Life Sci
, vol.56
, pp. 2065-2072
-
-
Cabral, G.A.1
Toney, D.M.2
Fischer-Stenger, K.3
Harrison, M.P.4
Marciano-Cabral, F.5
-
25
-
-
0032533247
-
Modulation and functional involvement of CB2 peripheral cannabinoid receptors during B-cell differentiation
-
Carayon P, Marchand J, Dussossoy D, Derocq JM, Jbilo O, Bord A, Bouaboula M, Galiegue S, Mondiere P, Penarier G, LeFur G, Defrance T, Casellas P (1998) Modulation and functional involvement of CB2 peripheral cannabinoid receptors during B-cell differentiation. Blood 92:3605-3615
-
(1998)
Blood
, vol.92
, pp. 3605-3615
-
-
Carayon, P.1
Marchand, J.2
Dussossoy, D.3
Derocq, J.M.4
Jbilo, O.5
Bord, A.6
Bouaboula, M.7
Galiegue, S.8
Mondiere, P.9
Penarier, G.10
LeFur, G.11
Defrance, T.12
Casellas, P.13
-
26
-
-
0035191240
-
Differential expression of the CB2 cannabinoid receptor by rodent macrophages and macrophage-like cells in relation to cell activation
-
Carlisle S, Marciano-Cabral F, Staab A, Ludwick C, Cabral G (2002) Differential expression of the CB2 cannabinoid receptor by rodent macrophages and macrophage-like cells in relation to cell activation. Int Immunopharmacol 2:69-82
-
(2002)
Int Immunopharmacol
, vol.2
, pp. 69-82
-
-
Carlisle, S.1
Marciano-Cabral, F.2
Staab, A.3
Ludwick, C.4
Cabral, G.5
-
27
-
-
1842428537
-
Cultured rat microglial cells synthesize the endocannabinoid 2-arachidonylglycerol, which increases proliferation via a CB2 receptor-dependent mechanism
-
Carrier EJ, Kearn CS, Barkmeier AJ, Breese NM, Yang W, Nithipatikom K, Pfister SL, Campbell WB, Hillard CJ (2004) Cultured rat microglial cells synthesize the endocannabinoid 2-arachidonylglycerol, which increases proliferation via a CB2 receptor-dependent mechanism. Mol Pharmacol 65:999-1007
-
(2004)
Mol Pharmacol
, vol.65
, pp. 999-1007
-
-
Carrier, E.J.1
Kearn, C.S.2
Barkmeier, A.J.3
Breese, N.M.4
Yang, W.5
Nithipatikom, K.6
Pfister, S.L.7
Campbell, W.B.8
Hillard, C.J.9
-
28
-
-
1542272558
-
Role of cannabinoid receptors in inhibiting macrophage costimulatory activity
-
Chuchawankul S, Shima M, Buckley NE, Hartmann CB, McCoy KL (2004) Role of cannabinoid receptors in inhibiting macrophage costimulatory activity. Int Immunopharmacol 4:265-278
-
(2004)
Int Immunopharmacol
, vol.4
, pp. 265-278
-
-
Chuchawankul, S.1
Shima, M.2
Buckley, N.E.3
Hartmann, C.B.4
McCoy, K.L.5
-
29
-
-
0030582449
-
Tetrahydrocannabinol inhibition of macrophage nitric oxide production
-
Coffey RG, Yamamoto Y, Snella E, Pross S (1996) Tetrahydrocannabinol inhibition of macrophage nitric oxide production. Biochem Pharmacol 52:743-751
-
(1996)
Biochem Pharmacol
, vol.52
, pp. 743-751
-
-
Coffey, R.G.1
Yamamoto, Y.2
Snella, E.3
Pross, S.4
-
30
-
-
17544371574
-
Cannabinoid induction of adenylate cyclase-mediated signal transduction and interleukin 2 (IL-2) expression in the murine T-cell line, EL4.IL-2
-
Condie R, Herring A, Koh WS, Lee M, Kaminski NE (1996) Cannabinoid induction of adenylate cyclase-mediated signal transduction and interleukin 2 (IL-2) expression in the murine T-cell line, EL4.IL-2. J Biol Chem 271:13175-13183
-
(1996)
J Biol Chem
, vol.271
, pp. 13175-13183
-
-
Condie, R.1
Herring, A.2
Koh, W.S.3
Lee, M.4
Kaminski, N.E.5
-
31
-
-
0037397037
-
Immunoregulation of a viral model of multiple sclerosis using the synthetic cannabinoid R+WIN55,212
-
Croxford JL, Miller SD (2003) Immunoregulation of a viral model of multiple sclerosis using the synthetic cannabinoid R+WIN55,212. J Clin Invest 111:1231-1240
-
(2003)
J Clin Invest
, vol.111
, pp. 1231-1240
-
-
Croxford, J.L.1
Miller, S.D.2
-
32
-
-
0030890230
-
9- tetrahydrocannabinol is mediated by nuclear factor kB and CB1 cannabinoid receptor
-
9-tetrahydrocannabinol is mediated by nuclear factor kB and CB1 cannabinoid receptor. DNA Cell Biol 16:301-309
-
(1997)
DNA Cell Biol
, vol.16
, pp. 301-309
-
-
Daaka, Y.1
Zhu, W.2
Friedman, H.3
Klein, T.W.4
-
33
-
-
0032821731
-
1′,1′-Dimethylheptyl-delta-8-tetrahydrocannabinol-11-oic acid: A novel, orally effective cannabinoid with analgesic and anti-inflammatory properties
-
Dajani EZ, Larsen KR, Taylor J, Dajani NE, Shahwan TG, Neeleman SD, Taylor MS, Dayton MT, Mir GN (1999) 1′,1′-Dimethylheptyl-delta-8- tetrahydrocannabinol-11-oic acid: a novel, orally effective cannabinoid with analgesic and anti-inflammatory properties. J Pharmacol Exp Ther 291:31-38
-
(1999)
J Pharmacol Exp Ther
, vol.291
, pp. 31-38
-
-
Dajani, E.Z.1
Larsen, K.R.2
Taylor, J.3
Dajani, N.E.4
Shahwan, T.G.5
Neeleman, S.D.6
Taylor, M.S.7
Dayton, M.T.8
Mir, G.N.9
-
34
-
-
0029127449
-
Cannabinoids enhance human B-cell growth at low nanomolar concentrations
-
Derocq J, Segui M, Marchand J, LeFur G, Casellas P (1995) Cannabinoids enhance human B-cell growth at low nanomolar concentrations. FEBS Lett 369:177-182
-
(1995)
FEBS Lett
, vol.369
, pp. 177-182
-
-
Derocq, J.1
Segui, M.2
Marchand, J.3
LeFur, G.4
Casellas, P.5
-
36
-
-
0024263922
-
Determination and characterization of a cannabinoid receptor in rat brain
-
Devane WA, Dysarz FA III, Johnson MR, Melvin LS, Howlett AC (1988) Determination and characterization of a cannabinoid receptor in rat brain. Mol Pharmacol 34:605-613
-
(1988)
Mol Pharmacol
, vol.34
, pp. 605-613
-
-
Devane, W.A.1
Dysarz III, F.A.2
Johnson, M.R.3
Melvin, L.S.4
Howlett, A.C.5
-
37
-
-
0027078685
-
Isolation and structure of a brain constituent that binds to the cannabinoid receptor
-
Devane WA, Hanus L, Breuer A, Pertwee RG, Stevenson LA, Griffin G, Gibson D, Mandelbaum A, Etinger A, Mechoulam R (1992) Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science 258:1946-1949
-
(1992)
Science
, vol.258
, pp. 1946-1949
-
-
Devane, W.A.1
Hanus, L.2
Breuer, A.3
Pertwee, R.G.4
Stevenson, L.A.5
Griffin, G.6
Gibson, D.7
Mandelbaum, A.8
Etinger, A.9
Mechoulam, R.10
-
38
-
-
1542283728
-
Cannabinoid CB2 receptor activation reduces mouse myocardial ischemia-reperfusion injury: Involvement of cytokine/chemokines and PMN
-
Di Filippo C, Rossi F, Rossi S, D'Amico M (2004) Cannabinoid CB2 receptor activation reduces mouse myocardial ischemia-reperfusion injury: involvement of cytokine/chemokines and PMN. J Leukoc Biol 75:453-459
-
(2004)
J Leukoc Biol
, vol.75
, pp. 453-459
-
-
Di Filippo, C.1
Rossi, F.2
Rossi, S.3
D'Amico, M.4
-
40
-
-
0026623545
-
9-tetrahydrocannabinol decreases cytotoxic T lymphocyte activity to herpes simplex virus type 1-infected cells
-
9- tetrahydrocannabinol decreases cytotoxic T lymphocyte activity to herpes simplex virus type 1-infected cells. Proc Soc Exp Biol Med 200:422-430
-
(1992)
Proc Soc Exp Biol Med
, vol.200
, pp. 422-430
-
-
Fischer-Stenger, K.1
Updegrove, A.W.2
Cabral, G.A.3
-
41
-
-
20444458379
-
The endocannabinoid signaling system: Pharmacological and therapeutic aspects
-
Fowler CJ, Holt S, Nilsson O, Jonsson KO, Tiger G, Jacobsson SO (2005) The endocannabinoid signaling system: pharmacological and therapeutic aspects. Pharmacol Biochem Behav 81:248-262
-
(2005)
Pharmacol Biochem Behav
, vol.81
, pp. 248-262
-
-
Fowler, C.J.1
Holt, S.2
Nilsson, O.3
Jonsson, K.O.4
Tiger, G.5
Jacobsson, S.O.6
-
42
-
-
0006425928
-
Immunosuppression by marijuana components
-
R Ader, DL Felten, N Cohen (eds) Academic, San Diego
-
Friedman H, Klein T, Specter S (1991) Immunosuppression by marijuana components. In: R Ader, DL Felten, N Cohen (eds) Psychoneuroimmunology, Academic, San Diego, pp 931-953.
-
(1991)
Psychoneuroimmunology
, pp. 931-953
-
-
Friedman, H.1
Klein, T.2
Specter, S.3
-
43
-
-
0029094470
-
Expression of central and peripheral cannabinoid receptors in human immune tissues and leukocyte subpopulations
-
Galieque S, Mary S, Marchand J, Dussossoy D, Carriere D, Carayon P, Bouaboula M, Shire D, Le Fur G, Casellas P (1995) Expression of central and peripheral cannabinoid receptors in human immune tissues and leukocyte subpopulations. Eur J Biochem 232:54-61
-
(1995)
Eur J Biochem
, vol.232
, pp. 54-61
-
-
Galieque, S.1
Mary, S.2
Marchand, J.3
Dussossoy, D.4
Carriere, D.5
Carayon, P.6
Bouaboula, M.7
Shire, D.8
Le Fur, G.9
Casellas, P.10
-
44
-
-
0030730585
-
Protection against septic shock and suppression of tumor necrosis factor alpha and nitric oxide production by dexanabinol (HU-211), a nonpsychotropic cannabinoid
-
Gallily R, Yamin A, Waksmann Y, Ovadia H, Weidenfeld J, Bar-Joseph A, Biegon A, Mechoulam R, Shohami E (1997) Protection against septic shock and suppression of tumor necrosis factor alpha and nitric oxide production by dexanabinol (HU-211), a nonpsychotropic cannabinoid. J Pharmacol Exp Ther 283:918-924
-
(1997)
J Pharmacol Exp Ther
, vol.283
, pp. 918-924
-
-
Gallily, R.1
Yamin, A.2
Waksmann, Y.3
Ovadia, H.4
Weidenfeld, J.5
Bar-Joseph, A.6
Biegon, A.7
Mechoulam, R.8
Shohami, E.9
-
45
-
-
33947489961
-
Isolation, structure, and partial synthesis of an active constituent of hashish
-
Gaoni Y, Mechoulam R (1964) Isolation, structure, and partial synthesis of an active constituent of hashish. J Am Chem Soc 86:1646-1647
-
(1964)
J Am Chem Soc
, vol.86
, pp. 1646-1647
-
-
Gaoni, Y.1
Mechoulam, R.2
-
46
-
-
0025878961
-
Molecular cloning of a human cannabinoid receptor which is also expressed in testis
-
Gerard CM, Mollereau C, Vassart G, Parmentier M (1991) Molecular cloning of a human cannabinoid receptor which is also expressed in testis. Biochem J 279:129-134
-
(1991)
Biochem J
, vol.279
, pp. 129-134
-
-
Gerard, C.M.1
Mollereau, C.2
Vassart, G.3
Parmentier, M.4
-
47
-
-
0030857066
-
Concurrent stimulation of cannabinoid CB1 and dopamine D2 receptors augments cAMP accumulation in striatal neurons: Evidence for a Gs linkage to the CB1 receptor
-
Glass M, Felder CC (1997) Concurrent stimulation of cannabinoid CB1 and dopamine D2 receptors augments cAMP accumulation in striatal neurons: evidence for a Gs linkage to the CB1 receptor. J Neurosci 17:5327-5333
-
(1997)
J Neurosci
, vol.17
, pp. 5327-5333
-
-
Glass, M.1
Felder, C.C.2
-
48
-
-
0035957425
-
2-Arachidonyl glyceryl ether, an endogenous agonist of the cannabinoid CB1 receptor
-
U S A
-
Hanus L, Abu-Lafi S, Fride E, Breuer A, Vogel Z, Shalev DE, Kustanovich I, Mechoulam R (2001) 2-Arachidonyl glyceryl ether, an endogenous agonist of the cannabinoid CB1 receptor. Proc Natl Acad Sci U S A 98:3662-3665
-
(2001)
Proc Natl Acad Sci
, vol.98
, pp. 3662-3665
-
-
Hanus, L.1
Abu-Lafi, S.2
Fride, E.3
Breuer, A.4
Vogel, Z.5
Shalev, D.E.6
Kustanovich, I.7
Mechoulam, R.8
-
49
-
-
3042818259
-
Vasorelaxant activities of the putative endocannabinoid virodhamine in rat isolated small mesenteric artery
-
Ho WS, Hiley CR (2004) Vasorelaxant activities of the putative endocannabinoid virodhamine in rat isolated small mesenteric artery. J Pharm Pharmacol 56:869-875
-
(2004)
J Pharm Pharmacol
, vol.56
, pp. 869-875
-
-
Ho, W.S.1
Hiley, C.R.2
-
50
-
-
0023914862
-
Nonclassical cannabinoid analgetics inhibit adenylate cyclase: Development of a cannabinoid receptor model
-
Howlett AC, Johnson MR, Melvin LS, Milne GM (1988) Nonclassical cannabinoid analgetics inhibit adenylate cyclase: development of a cannabinoid receptor model. Mol Pharmacol 33:297-302
-
(1988)
Mol Pharmacol
, vol.33
, pp. 297-302
-
-
Howlett, A.C.1
Johnson, M.R.2
Melvin, L.S.3
Milne, G.M.4
-
51
-
-
18444376760
-
International Union of Pharmacology. XXVII. Classification of cannabinoid receptors
-
Howlett AC, Barth F, Bonner TI, Cabral G, Casellas P, Devane WA, Felder CC, Herkenham M, Mackie K, Martin BR, Mechoulam R, Pertwee RG (2002) International Union of Pharmacology. XXVII. Classification of cannabinoid receptors. Pharmacol Rev 54:161-202
-
(2002)
Pharmacol Rev
, vol.54
, pp. 161-202
-
-
Howlett, A.C.1
Barth, F.2
Bonner, T.I.3
Cabral, G.4
Casellas, P.5
Devane, W.A.6
Felder, C.C.7
Herkenham, M.8
Mackie, K.9
Martin, B.R.10
Mechoulam, R.11
Pertwee, R.G.12
-
52
-
-
4644331847
-
Cannabinoid physiology and pharmacology: 30 Years of progress
-
Howlett AC, Breivogel CS, Childers SR, Deadwyler SA, Hampson RE, Porrino LJ (2004) Cannabinoid physiology and pharmacology: 30 years of progress. Neuropharmacology 47:345-358
-
(2004)
Neuropharmacology
, vol.47
, pp. 345-358
-
-
Howlett, A.C.1
Breivogel, C.S.2
Childers, S.R.3
Deadwyler, S.A.4
Hampson, R.E.5
Porrino, L.J.6
-
53
-
-
0041836218
-
Activation of CB2 cannabinoid receptors by AM1241 inhibits experimental neuropathic pain: Pain inhibition by receptors not present in the CNS
-
U S A
-
Ibrahim MM, Deng H, Zvonok A, Cockayne DA, Kwan J, Mata HP, Vanderah TW, Lai J, Porreca F, Makriyannis A, Malan TP, Jr (2003) Activation of CB2 cannabinoid receptors by AM1241 inhibits experimental neuropathic pain: pain inhibition by receptors not present in the CNS. Proc Natl Acad Sci U S A 100:10529-10533
-
(2003)
Proc Natl Acad Sci
, vol.100
, pp. 10529-10533
-
-
Ibrahim, M.M.1
Deng, H.2
Zvonok, A.3
Cockayne, D.A.4
Kwan, J.5
Mata, H.P.6
Vanderah, T.W.7
Lai, J.8
Porreca, F.9
Makriyannis, A.10
Malan Jr., T.P.11
-
54
-
-
0038845604
-
Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors
-
U S A
-
Jarai Z, Wagner JA, Varga K, Lake KD, Compton DR, Martin BR, Zimmer AM, Bonner TI, Buckley NE, Mezey E, Razdan RK, Zimmer A, Kunos G (1999) Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors. Proc Natl Acad Sci U S A 96:14136-14141
-
(1999)
Proc Natl Acad Sci
, vol.96
, pp. 14136-14141
-
-
Jarai, Z.1
Wagner, J.A.2
Varga, K.3
Lake, K.D.4
Compton, D.R.5
Martin, B.R.6
Zimmer, A.M.7
Bonner, T.I.8
Buckley, N.E.9
Mezey, E.10
Razdan, R.K.11
Zimmer, A.12
Kunos, G.13
-
55
-
-
0029790065
-
Attenuation of inducible nitric oxide synthase gene expression by D9-tetrahydrocannabinol is mediated through the inhibition of nuclear factor-kB/Rel activation
-
Jeon YJ, Yang K, Pulaski JT, Kaminski NE (1996) Attenuation of inducible nitric oxide synthase gene expression by D9-tetrahydrocannabinol is mediated through the inhibition of nuclear factor-kB/Rel activation. Mol Pharmacol 50:334-341
-
(1996)
Mol Pharmacol
, vol.50
, pp. 334-341
-
-
Jeon, Y.J.1
Yang, K.2
Pulaski, J.T.3
Kaminski, N.E.4
-
56
-
-
0037089221
-
Hematopoietic cells expressing the peripheral cannabinoid receptor migrate in response to the endocannabinoid 2-arachidonoylglycerol
-
Jorda MA, Verbakel SE, Valk PJ, Vankan-Berkhoudt YV, Maccarrone M, Finazzi-Agro A, Lowenberg B, Delwel R (2002) Hematopoietic cells expressing the peripheral cannabinoid receptor migrate in response to the endocannabinoid 2-arachidonoylglycerol. Blood 99:2786-2793
-
(2002)
Blood
, vol.99
, pp. 2786-2793
-
-
Jorda, M.A.1
Verbakel, S.E.2
Valk, P.J.3
Vankan-Berkhoudt, Y.V.4
Maccarrone, M.5
Finazzi-Agro, A.6
Lowenberg, B.7
Delwel, R.8
-
58
-
-
0027103851
-
Identification of a functionally relevant cannabinoid receptor on mouse spleen cells that is involved in cannabinoid-mediated immune modulation
-
Kaminski NE, Abood ME, Kessler FK, Martin BR, Schatz AR (1992) Identification of a functionally relevant cannabinoid receptor on mouse spleen cells that is involved in cannabinoid-mediated immune modulation. Mol Pharmacol 42:736-742
-
(1992)
Mol Pharmacol
, vol.42
, pp. 736-742
-
-
Kaminski, N.E.1
Abood, M.E.2
Kessler, F.K.3
Martin, B.R.4
Schatz, A.R.5
-
59
-
-
0027998221
-
Suppression of the humoral immune response by cannabinoids is partially mediated through inhibition of adenylate cyclase by a pertussis toxin-sensitive G-protein coupled mechanism
-
Kaminski N, Koh WS, Yang KH, Lee M, Kessler FK (1994) Suppression of the humoral immune response by cannabinoids is partially mediated through inhibition of adenylate cyclase by a pertussis toxin-sensitive G-protein coupled mechanism. Biochem Pharmacol 48:1899-1908
-
(1994)
Biochem Pharmacol
, vol.48
, pp. 1899-1908
-
-
Kaminski, N.1
Koh, W.S.2
Yang, K.H.3
Lee, M.4
Kessler, F.K.5
-
60
-
-
0042934012
-
Evidence for cannabinoid receptor-dependent and -independent mechanisms of action in leukocytes
-
Kaplan BL, Rockwell CE, Kaminski NE (2003) Evidence for cannabinoid receptor-dependent and -independent mechanisms of action in leukocytes. J Pharmacol Exp Ther 306:1077-1085
-
(2003)
J Pharmacol Exp Ther
, vol.306
, pp. 1077-1085
-
-
Kaplan, B.L.1
Rockwell, C.E.2
Kaminski, N.E.3
-
61
-
-
0023838835
-
Suppression by cannabinoids of a cloned cell line with natural killer cell activity
-
Kawakami Y, Klein TW, Newton C, McCarthy CA, Djeu J, Dennert G, Specter S, Friedman H (1988) Suppression by cannabinoids of a cloned cell line with natural killer cell activity. Proc Soc Exp Biol Med 187:355-359
-
(1988)
Proc Soc Exp Biol Med
, vol.187
, pp. 355-359
-
-
Kawakami, Y.1
Klein, T.W.2
Newton, C.3
McCarthy, C.A.4
Djeu, J.5
Dennert, G.6
Specter, S.7
Friedman, H.8
-
62
-
-
0042591269
-
2-Arachidonoylglycerol induces the migration of HL-60 cells differentiated into macrophage-like cells and human peripheral blood monocytes through the cannabinoid CB2 receptor-dependent mechanism
-
Kishimoto S, Gokoh M, Oka S, Muramatsu M, Kajiwara T, Waku K, Sugiura T (2003) 2-Arachidonoylglycerol induces the migration of HL-60 cells differentiated into macrophage-like cells and human peripheral blood monocytes through the cannabinoid CB2 receptor-dependent mechanism. J Biol Chem 278:24469-24475
-
(2003)
J Biol Chem
, vol.278
, pp. 24469-24475
-
-
Kishimoto, S.1
Gokoh, M.2
Oka, S.3
Muramatsu, M.4
Kajiwara, T.5
Waku, K.6
Sugiura, T.7
-
63
-
-
2442706289
-
2-Arachidonoylglycerol, an endogenous cannabinoid receptor ligand, induces accelerated production of chemokines in HL-60 cells
-
Tokyo
-
Kishimoto S, Kobayashi Y, Oka S, Gokoh M, Waku K, Sugiura T (2004) 2-Arachidonoylglycerol, an endogenous cannabinoid receptor ligand, induces accelerated production of chemokines in HL-60 cells. J Biochem (Tokyo) 135:517-524
-
(2004)
J Biochem
, vol.135
, pp. 517-524
-
-
Kishimoto, S.1
Kobayashi, Y.2
Oka, S.3
Gokoh, M.4
Waku, K.5
Sugiura, T.6
-
64
-
-
18844400058
-
Cannabinoid-based drugs as anti-inflammatory therapeutics
-
Klein TW (2005) Cannabinoid-based drugs as anti-inflammatory therapeutics. Nat Rev Immunol 5:400-411
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 400-411
-
-
Klein, T.W.1
-
65
-
-
0002741491
-
Modulation of murine immune cell function by marijuana components
-
R Watson (ed) Boca Raton, FL, CRC Press
-
Klein TW, Friedman H (1990) Modulation of murine immune cell function by marijuana components. In: R Watson (ed) Drugs of Abuse and Immune Function, Boca Raton, FL, CRC Press, pp 87-111
-
(1990)
Drugs of Abuse and Immune Function
, pp. 87-111
-
-
Klein, T.W.1
Friedman, H.2
-
66
-
-
84907112385
-
The effect of delta-9-tetrahydrocannabinol and 11-hydroxy-delta-9- tetrahydrocannabinol on T lymphocyte and B lymphocyte mitogen responses
-
Klein TW, Newton CA, Widen R, Friedman H (1985) The effect of delta-9-tetrahydrocannabinol and 11-hydroxy-delta-9-tetrahydrocannabinol on T lymphocyte and B lymphocyte mitogen responses. J Immunopharmacol 7:451-466
-
(1985)
J Immunopharmacol
, vol.7
, pp. 451-466
-
-
Klein, T.W.1
Newton, C.A.2
Widen, R.3
Friedman, H.4
-
67
-
-
0025865796
-
Marijuana components suppress induction and cytolytic function of murine cytotoxic T cells in vitro and in vivo
-
Klein TW, Kawakami Y, Newton C, Friedman H (1991) Marijuana components suppress induction and cytolytic function of murine cytotoxic T cells in vitro and in vivo. J Toxicol Environ Health 32:465-477
-
(1991)
J Toxicol Environ Health
, vol.32
, pp. 465-477
-
-
Klein, T.W.1
Kawakami, Y.2
Newton, C.3
Friedman, H.4
-
68
-
-
0028016088
-
Resistance to Legionella pneumophila suppressed by the marijuana component, tetrahydrocannabinol
-
Klein TW, Newton C, Friedman H (1994) Resistance to Legionella pneumophila suppressed by the marijuana component, tetrahydrocannabinol. J Infect Dis 169:1177-1179
-
(1994)
J Infect Dis
, vol.169
, pp. 1177-1179
-
-
Klein, T.W.1
Newton, C.2
Friedman, H.3
-
69
-
-
0034660138
-
D9-tetrahydrocannabinol treatment suppresses immunity and early IFNγ, IL-12, and IL-12 receptor β2 responses to Legionella pneumophila infection
-
Klein TW, Newton CA, Nakachi N, Friedman H (2000) D9-tetrahydrocannabinol treatment suppresses immunity and early IFNγ, IL-12, and IL-12 receptor β2 responses to Legionella pneumophila infection. J Immunol 164:6461-6466
-
(2000)
J Immunol
, vol.164
, pp. 6461-6466
-
-
Klein, T.W.1
Newton, C.A.2
Nakachi, N.3
Friedman, H.4
-
72
-
-
0346350327
-
The cannabinoid system and immune modulation
-
Klein TW, Newton C, Larsen K, Lu L, Perkins I, Nong L, Friedman H (2003) The cannabinoid system and immune modulation. J Leukoc Biol 74:486-496
-
(2003)
J Leukoc Biol
, vol.74
, pp. 486-496
-
-
Klein, T.W.1
Newton, C.2
Larsen, K.3
Lu, L.4
Perkins, I.5
Nong, L.6
Friedman, H.7
-
73
-
-
0036192049
-
Dexanabinol (HU-211) in the treatment of severe closed head injury: A randomized, placebo-controlled, phase II clinical trial
-
Knoller N, Levi L, Shoshan I, Reichenthal E, Razon N, Rappaport ZH, Biegon A (2002) Dexanabinol (HU-211) in the treatment of severe closed head injury: a randomized, placebo-controlled, phase II clinical trial. Crit Care Med 30:548-554
-
(2002)
Crit Care Med
, vol.30
, pp. 548-554
-
-
Knoller, N.1
Levi, L.2
Shoshan, I.3
Reichenthal, E.4
Razon, N.5
Rappaport, Z.H.6
Biegon, A.7
-
74
-
-
2442425261
-
Further evidence for the existence of a specific process for the membrane transport of anandamide
-
Ligresti A, Morera E, van der Stelt M, Monory K, Lutz B, Ortar G, Di Marzo V (2004) Further evidence for the existence of a specific process for the membrane transport of anandamide. Biochem J 380:265-272
-
(2004)
Biochem J
, vol.380
, pp. 265-272
-
-
Ligresti, A.1
Morera, E.2
Van Der Stelt, M.3
Monory, K.4
Lutz, B.5
Ortar, G.6
Di Marzo, V.7
-
75
-
-
0038745585
-
Activation and binding of peroxisome proliferator-activated receptor gamma by synthetic cannabinoid ajulemic acid
-
Liu J, Li H, Burstein SH, Zurier RB, Chen JD (2003) Activation and binding of peroxisome proliferator-activated receptor gamma by synthetic cannabinoid ajulemic acid. Mol Pharmacol 63:983-992
-
(2003)
Mol Pharmacol
, vol.63
, pp. 983-992
-
-
Liu, J.1
Li, H.2
Burstein, S.H.3
Zurier, R.B.4
Chen, J.D.5
-
77
-
-
0035877059
-
Progesterone up-regulates anandamide hydrolase in human lymphocytes: Role of cytokines and implications for fertility
-
Maccarrone M, Valensise H, Bari M, Lazzarin N, Romanini C, Finazzi-Agro A (2001) Progesterone up-regulates anandamide hydrolase in human lymphocytes: role of cytokines and implications for fertility. J Immunol 166:7183-7189
-
(2001)
J Immunol
, vol.166
, pp. 7183-7189
-
-
Maccarrone, M.1
Valensise, H.2
Bari, M.3
Lazzarin, N.4
Romanini, C.5
Finazzi-Agro, A.6
-
78
-
-
0034662868
-
The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis
-
U S A
-
Malfait AM, Gallily R, Sumariwalla PF, Malik AS, Andreakos E, Mechoulam R, Feldmann M (2000) The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis [see comments]. Proc Natl Acad Sci U S A 97:9561-9566
-
(2000)
Proc Natl Acad Sci
, vol.97
, pp. 9561-9566
-
-
Malfait, A.M.1
Gallily, R.2
Sumariwalla, P.F.3
Malik, A.S.4
Andreakos, E.5
Mechoulam, R.6
Feldmann, M.7
-
79
-
-
0023850652
-
Biology of Naegleria spp.
-
Marciano-Cabral F (1988) Biology of Naegleria spp. Microbiol Rev 52:114-133
-
(1988)
Microbiol Rev
, vol.52
, pp. 114-133
-
-
Marciano-Cabral, F.1
-
80
-
-
0033985356
-
Relative involvement of cannabinoid CB(1) and CB(2) receptors in the Delta(9)-tetrahydrocannabinol-induced inhibition of natural killer activity
-
Massi P, Fuzio D, Vigano D, Sacerdote P, Parolaro D (2000) Relative involvement of cannabinoid CB(1) and CB(2) receptors in the Delta(9)- tetrahydrocannabinol-induced inhibition of natural killer activity. Eur J Pharmacol 387:343-347
-
(2000)
Eur J Pharmacol
, vol.387
, pp. 343-347
-
-
Massi, P.1
Fuzio, D.2
Vigano, D.3
Sacerdote, P.4
Parolaro, D.5
-
81
-
-
0025325535
-
Structure of cannabinoid receptor and functional expression of the cloned cDNA
-
Matsuda LA, Lolait SJ, Brownstein MJ, Young AC, Bonner TI (1990) Structure of cannabinoid receptor and functional expression of the cloned cDNA. Nature 346:561-564
-
(1990)
Nature
, vol.346
, pp. 561-564
-
-
Matsuda, L.A.1
Lolait, S.J.2
Brownstein, M.J.3
Young, A.C.4
Bonner, T.I.5
-
83
-
-
0033057247
-
Cannabinoid inhibition of the processing of intact lysozyme by macrophages: Evidence for CB2 receptor participation
-
McCoy KL, Matveyeva M, Carlisle SJ, Cabral GA (1999) Cannabinoid inhibition of the processing of intact lysozyme by macrophages: evidence for CB2 receptor participation. J Pharmacol Exp Ther 289:1620-1625
-
(1999)
J Pharmacol Exp Ther
, vol.289
, pp. 1620-1625
-
-
McCoy, K.L.1
Matveyeva, M.2
Carlisle, S.J.3
Cabral, G.A.4
-
84
-
-
0029012014
-
Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors
-
Mechoulam R, Ben-Shabat S, Hanus L, Ligumsky M, Kaminski NE, Schatz AR, Gopher A, Almog S, Martin BR, Compton DR, Pertwee RG, Griffin G, Bayewitch M, Barg J, Vogel Z (1995) Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors. Biochem Pharmacol 50:83-90
-
(1995)
Biochem Pharmacol
, vol.50
, pp. 83-90
-
-
Mechoulam, R.1
Ben-Shabat, S.2
Hanus, L.3
Ligumsky, M.4
Kaminski, N.E.5
Schatz, A.R.6
Gopher, A.7
Almog, S.8
Martin, B.R.9
Compton, D.R.10
Pertwee, R.G.11
Griffin, G.12
Bayewitch, M.13
Barg, J.14
Vogel, Z.15
-
86
-
-
0022348142
-
Delta-9-tetrahydrocannabinol decreases host resistance to herpes simplex virus type 2 vaginal infection in the B6C3F1 mouse
-
Mishkin EM, Cabral GA (1985) Delta-9-tetrahydrocannabinol decreases host resistance to herpes simplex virus type 2 vaginal infection in the B6C3F1 mouse. J Gen Virol 66:2539-2549
-
(1985)
J Gen Virol
, vol.66
, pp. 2539-2549
-
-
Mishkin, E.M.1
Cabral, G.A.2
-
87
-
-
19544391242
-
Effect of the cannabinoid ajulemic acid on rat models of neuropathic and inflammatory pain
-
Mitchell VA, Aslan S, Safaei R, Vaughan CW (2005) Effect of the cannabinoid ajulemic acid on rat models of neuropathic and inflammatory pain. Neurosci Lett 382:231-235
-
(2005)
Neurosci Lett
, vol.382
, pp. 231-235
-
-
Mitchell, V.A.1
Aslan, S.2
Safaei, R.3
Vaughan, C.W.4
-
88
-
-
0031866598
-
The endogenous cannabinoid anandamide potentiates interleukin-6 production by astrocytes infected with Theiler's murine encephalomyelitis virus by a receptor-mediated pathway
-
Molina-Holgado F, Molina-Holgado E, Guaza C (1998) The endogenous cannabinoid anandamide potentiates interleukin-6 production by astrocytes infected with Theiler's murine encephalomyelitis virus by a receptor-mediated pathway. FEBS Lett 433:139-142
-
(1998)
FEBS Lett
, vol.433
, pp. 139-142
-
-
Molina-Holgado, F.1
Molina-Holgado, E.2
Guaza, C.3
-
89
-
-
0041842648
-
Endogenous interleukin-1 receptor antagonist mediates anti-inflammatory and neuroprotective actions of cannabinoids in neurons and glia
-
Molina-Holgado F, Pinteaux E, Moore JD, Molina-Holgado E, Guaza C, Gibson RM, Rothwell NJ (2003) Endogenous interleukin-1 receptor antagonist mediates anti-inflammatory and neuroprotective actions of cannabinoids in neurons and glia. J Neurosci 23:6470-6474
-
(2003)
J Neurosci
, vol.23
, pp. 6470-6474
-
-
Molina-Holgado, F.1
Pinteaux, E.2
Moore, J.D.3
Molina-Holgado, E.4
Guaza, C.5
Gibson, R.M.6
Rothwell, N.J.7
-
90
-
-
0018411107
-
Effects of cannabinoids on host resistance to Listeria monocytogenes and herpes simplex virus
-
Morahan PS, Klykken PC, Smith SH, Harris LS, Munson AE (1979) Effects of cannabinoids on host resistance to Listeria monocytogenes and herpes simplex virus. Infect Immun 23:670-674
-
(1979)
Infect Immun
, vol.23
, pp. 670-674
-
-
Morahan, P.S.1
Klykken, P.C.2
Smith, S.H.3
Harris, L.S.4
Munson, A.E.5
-
91
-
-
0027515373
-
Molecular characterization of a peripheral receptor for cannabinoids
-
Munro S, Thomas KL, Abu-Shaar M (1993) Molecular characterization of a peripheral receptor for cannabinoids. Nature 365:61-65
-
(1993)
Nature
, vol.365
, pp. 61-65
-
-
Munro, S.1
Thomas, K.L.2
Abu-Shaar, M.3
-
92
-
-
0026715103
-
9- tetrahydrocannabinol after stimulation with concanavalin A, phytohemagglutinin, or anti-CD3 antibody
-
9-tetrahydrocannabinol after stimulation with concanavalin A, phytohemagglutinin, or anti-CD3 antibody. Proc Soc Exp Biol Med 201:165-168
-
(1992)
Proc Soc Exp Biol Med
, vol.201
, pp. 165-168
-
-
Nakano, Y.1
Pross, S.H.2
Friedman, H.3
-
93
-
-
0242584643
-
Selective ligands and cellular effectors of a G protein-coupled endothelial cannabinoid receptor
-
Offertaler L, Mo FM, Batkai S, Liu J, Begg M, Razdan RK, Martin BR, Bukoski RD, Kunos G (2003) Selective ligands and cellular effectors of a G protein-coupled endothelial cannabinoid receptor. Mol Pharmacol 63:699-705
-
(2003)
Mol Pharmacol
, vol.63
, pp. 699-705
-
-
Offertaler, L.1
Mo, F.M.2
Batkai, S.3
Liu, J.4
Begg, M.5
Razdan, R.K.6
Martin, B.R.7
Bukoski, R.D.8
Kunos, G.9
-
94
-
-
1242294480
-
Molecular characterization of a phospholipase D generating anandamide and its congeners
-
Okamoto Y, Morishita J, Tsuboi K, Tonai T, Ueda N (2004) Molecular characterization of a phospholipase D generating anandamide and its congeners. J Biol Chem 279:5298-5305
-
(2004)
J Biol Chem
, vol.279
, pp. 5298-5305
-
-
Okamoto, Y.1
Morishita, J.2
Tsuboi, K.3
Tonai, T.4
Ueda, N.5
-
95
-
-
0035807380
-
An endogenous cannabinoid (2-AG) is neuroprotective after brain injury
-
Panikashvili D, Simeonidou C, Ben-Shabat S, Hanus L, Breuer A, Mechoulam R, Shohami E (2001) An endogenous cannabinoid (2-AG) is neuroprotective after brain injury. Nature 413:527-531
-
(2001)
Nature
, vol.413
, pp. 527-531
-
-
Panikashvili, D.1
Simeonidou, C.2
Ben-Shabat, S.3
Hanus, L.4
Breuer, A.5
Mechoulam, R.6
Shohami, E.7
-
96
-
-
0036669791
-
Cannabinoids and multiple sclerosis
-
Pertwee RG (2002) Cannabinoids and multiple sclerosis. Pharmacol Ther 95:165-174
-
(2002)
Pharmacol Ther
, vol.95
, pp. 165-174
-
-
Pertwee, R.G.1
-
97
-
-
0036260823
-
Characterization of a novel endocannabinoid, virodhamine, with antagonist activity at the CB1 receptor
-
Porter AC, Sauer JM, Knierman MD, Becker GW, Berna MJ, Bao J, Nomikos GG, Carter P, Bymaster FP, Leese AB, Felder CC (2002) Characterization of a novel endocannabinoid, virodhamine, with antagonist activity at the CB1 receptor. J Pharmacol Exp Ther 301:1020-1024
-
(2002)
J Pharmacol Exp Ther
, vol.301
, pp. 1020-1024
-
-
Porter, A.C.1
Sauer, J.M.2
Knierman, M.D.3
Becker, G.W.4
Berna, M.J.5
Bao, J.6
Nomikos, G.G.7
Carter, P.8
Bymaster, F.P.9
Leese, A.B.10
Felder, C.C.11
-
98
-
-
0033986604
-
Cannabinoids inhibit LPS-inducible cytokine mRNA expression in rat microglial cells
-
Puffenbarger RA, Boothe AC, Cabral GA (2000) Cannabinoids inhibit LPS-inducible cytokine mRNA expression in rat microglial cells. Glia 29:58-69
-
(2000)
Glia
, vol.29
, pp. 58-69
-
-
Puffenbarger, R.A.1
Boothe, A.C.2
Cabral, G.A.3
-
99
-
-
14244264502
-
Prevention of Alzheimer's disease pathology by cannabinoids: Neuroprotection mediated by blockade of microglial activation
-
Ramirez BG, Blazquez C, Gomez del Pulgar T, Guzman M, Ceballos MLde (2005) Prevention of Alzheimer's disease pathology by cannabinoids: neuroprotection mediated by blockade of microglial activation. J Neurosci 25:1904-1913
-
(2005)
J Neurosci
, vol.25
, pp. 1904-1913
-
-
Ramirez, B.G.1
Blazquez, C.2
Gomez Del Pulgar, T.3
Guzman, M.4
Ceballos, M.L.D.5
-
100
-
-
0842321791
-
Distinct expression profiles of the peripheral cannabinoid receptor in lymphoid tissues depending on receptor activation status
-
Rayman N, Lam KH, Laman JD, Simons PJ, Lowenberg B, Sonneveld P, Delwel R (2004) Distinct expression profiles of the peripheral cannabinoid receptor in lymphoid tissues depending on receptor activation status. J Immunol 172:2111-2117
-
(2004)
J Immunol
, vol.172
, pp. 2111-2117
-
-
Rayman, N.1
Lam, K.H.2
Laman, J.D.3
Simons, P.J.4
Lowenberg, B.5
Sonneveld, P.6
Delwel, R.7
-
101
-
-
0030756533
-
Cannabinol derivatives: Binding to cannabinoid receptors and inhibition of adenylylcyclase
-
Rhee MH, Vogel Z, Barg J, Bayewitch M, Levy R, Hanus L, Breuer A, Mechoulam R (1997) Cannabinol derivatives: binding to cannabinoid receptors and inhibition of adenylylcyclase. J Med Chem 40:3228-3233
-
(1997)
J Med Chem
, vol.40
, pp. 3228-3233
-
-
Rhee, M.H.1
Vogel, Z.2
Barg, J.3
Bayewitch, M.4
Levy, R.5
Hanus, L.6
Breuer, A.7
Mechoulam, R.8
-
102
-
-
25444530723
-
Randomized, controlled trial of cannabis-based medicine in central pain in multiple sclerosis
-
Rog DJ, Nurmikko TJ, Friede T, Young CA (2005) Randomized, controlled trial of cannabis-based medicine in central pain in multiple sclerosis. Neurology 65:812-819
-
(2005)
Neurology
, vol.65
, pp. 812-819
-
-
Rog, D.J.1
Nurmikko, T.J.2
Friede, T.3
Young, C.A.4
-
103
-
-
1542346866
-
Monoglyceride lipase-like enzymatic activity is responsible for hydrolysis of 2-arachidonoylglycerol in rat cerebellar membranes
-
Saario SM, Savinainen JR, Laitinen JT, Jarvinen T, Niemi R (2004) Monoglyceride lipase-like enzymatic activity is responsible for hydrolysis of 2-arachidonoylglycerol in rat cerebellar membranes. Biochem Pharmacol 67:1381-1387
-
(2004)
Biochem Pharmacol
, vol.67
, pp. 1381-1387
-
-
Saario, S.M.1
Savinainen, J.R.2
Laitinen, J.T.3
Jarvinen, T.4
Niemi, R.5
-
104
-
-
0034703186
-
In vivo and in vitro treatment with the synthetic cannabinoid CP55, 940 decreases the in vitro migration of macrophages in the rat: Involvement of both CB1 and CB2 receptors
-
Sacerdote P, Massi P, Panerai AE, Parolaro D (2000) In vivo and in vitro treatment with the synthetic cannabinoid CP55, 940 decreases the in vitro migration of macrophages in the rat: involvement of both CB1 and CB2 receptors. J Neuroimmunol 109:155-163
-
(2000)
J Neuroimmunol
, vol.109
, pp. 155-163
-
-
Sacerdote, P.1
Massi, P.2
Panerai, A.E.3
Parolaro, D.4
-
105
-
-
0027999501
-
Anandamide, an endogenous cannabinoid receptor agonist inhibits lymphocyte proliferation and induces apoptosis
-
Schwarz H, Blanco FJ, Lotz M (1994) Anandamide, an endogenous cannabinoid receptor agonist inhibits lymphocyte proliferation and induces apoptosis. J Neuroimmunol 55:107-115
-
(1994)
J Neuroimmunol
, vol.55
, pp. 107-115
-
-
Schwarz, H.1
Blanco, F.J.2
Lotz, M.3
-
106
-
-
0031047431
-
Cytokine production in the brain following closed head injury: Dexanabinol (HU-211) is a novel TNF-alpha inhibitor and an effective neuroprotectant
-
Shohami E, Gallily R, Mechoulam R, Bass R, Ben-Hur T (1997) Cytokine production in the brain following closed head injury: dexanabinol (HU-211) is a novel TNF-alpha inhibitor and an effective neuroprotectant. J Neuroimmunol 72:169-177
-
(1997)
J Neuroimmunol
, vol.72
, pp. 169-177
-
-
Shohami, E.1
Gallily, R.2
Mechoulam, R.3
Bass, R.4
Ben-Hur, T.5
-
107
-
-
0034069673
-
Effects of cannabinoid receptor agonist and antagonist ligands on production of inflammatory cytokines and anti-inflammatory interleukin-10 in endotoxemic mice
-
Smith SR, Terminelli C, Denhardt G (2000) Effects of cannabinoid receptor agonist and antagonist ligands on production of inflammatory cytokines and anti-inflammatory interleukin-10 in endotoxemic mice. J Pharmacol Exp Ther 293:136-150
-
(2000)
J Pharmacol Exp Ther
, vol.293
, pp. 136-150
-
-
Smith, S.R.1
Terminelli, C.2
Denhardt, G.3
-
109
-
-
0033801063
-
2-Arachidonyl-glycerol stimulates nitric oxide release from human immune and vascular tissues and invertebrate immunocytes by cannabinoid receptor 1
-
Stefano GB, Bilfinger TV, Rialas CM, Deutsch DG (2000) 2-Arachidonyl-glycerol stimulates nitric oxide release from human immune and vascular tissues and invertebrate immunocytes by cannabinoid receptor 1. Pharmacol Res 42:317-322
-
(2000)
Pharmacol Res
, vol.42
, pp. 317-322
-
-
Stefano, G.B.1
Bilfinger, T.V.2
Rialas, C.M.3
Deutsch, D.G.4
-
110
-
-
0030066244
-
Enzymatic synthesis of anandamide, an endogenous cannabinoid receptor ligand, through N-acylphosphatidylethanolamine pathway in testis: Involvement of Ca(2+)-dependent transacylase and phosphodiesterase activities
-
Sugiura T, Kondo S, Sukagawa A, Tonegawa T, Nakane S, Yamashita A, Waku K (1996) Enzymatic synthesis of anandamide, an endogenous cannabinoid receptor ligand, through N-acylphosphatidylethanolamine pathway in testis: involvement of Ca(2+)-dependent transacylase and phosphodiesterase activities. Biochem Biophys Res Commun 218:113-117
-
(1996)
Biochem Biophys Res Commun
, vol.218
, pp. 113-117
-
-
Sugiura, T.1
Kondo, S.2
Sukagawa, A.3
Tonegawa, T.4
Nakane, S.5
Yamashita, A.6
Waku, K.7
-
111
-
-
0036019386
-
Biosynthesis and degradation of anandamide and 2-arachidonoylglycerol and their possible physiological significance
-
Sugiura T, Kobayashi Y, Oka S, Waku K (2002) Biosynthesis and degradation of anandamide and 2-arachidonoylglycerol and their possible physiological significance. Prostaglandins Leukot Essent Fat Acids 66:173-192
-
(2002)
Prostaglandins Leukot Essent Fat Acids
, vol.66
, pp. 173-192
-
-
Sugiura, T.1
Kobayashi, Y.2
Oka, S.3
Waku, K.4
-
112
-
-
4043096916
-
Does the cannabinoid dronabinol reduce central pain in multiple sclerosis? Randomised double blind placebo controlled crossover trial
-
Svendsen KB, Jensen TS, Bach FW (2004) Does the cannabinoid dronabinol reduce central pain in multiple sclerosis? Randomised double blind placebo controlled crossover trial. BMJ 329:253,
-
(2004)
BMJ
, vol.329
, pp. 253
-
-
Svendsen, K.B.1
Jensen, T.S.2
Bach, F.W.3
-
114
-
-
0030753167
-
Anandamide, a natural ligand for the peripheral cannabinoid receptor is a novel synergistic growth factor for hematopoietic cells
-
Valk P, Verbakel S, Vankan Y, Hol S, Mancham S, Ploemacher R, Mayen A, Lowenberg B, Delwel R (1997) Anandamide, a natural ligand for the peripheral cannabinoid receptor is a novel synergistic growth factor for hematopoietic cells. Blood 90:1448-1457
-
(1997)
Blood
, vol.90
, pp. 1448-1457
-
-
Valk, P.1
Verbakel, S.2
Vankan, Y.3
Hol, S.4
Mancham, S.5
Ploemacher, R.6
Mayen, A.7
Lowenberg, B.8
Delwel, R.9
-
115
-
-
4344571664
-
Efficacy, safety and tolerability of an orally administered cannabis extract in the treatment of spasticity in patients with multiple sclerosis: A randomized, double-blind, placebo-controlled, crossover study
-
Vaney C, Heinzel-Gutenbrunner M, Jobin P, Tschopp F, Gattlen B, Hagen U, Schnelle M, Reif M (2004) Efficacy, safety and tolerability of an orally administered cannabis extract in the treatment of spasticity in patients with multiple sclerosis: a randomized, double-blind, placebo-controlled, crossover study. Mult Scler 10:417-424
-
(2004)
Mult Scler
, vol.10
, pp. 417-424
-
-
Vaney, C.1
Heinzel-Gutenbrunner, M.2
Jobin, P.3
Tschopp, F.4
Gattlen, B.5
Hagen, U.6
Schnelle, M.7
Reif, M.8
-
116
-
-
0031823187
-
Platelet- and macrophage-derived endogenous cannabinoids are involved in endotoxin-induced hypotension
-
Varga K, Wagner JA, Bridgen DT, Kunos G (1998) Platelet- and macrophage-derived endogenous cannabinoids are involved in endotoxin-induced hypotension. FASEB J 12:1035-1044
-
(1998)
FASEB J
, vol.12
, pp. 1035-1044
-
-
Varga, K.1
Wagner, J.A.2
Bridgen, D.T.3
Kunos, G.4
-
117
-
-
0037704448
-
Neuroprotection by the endogenous cannabinoid anandamide and arvanil against in vivo excitotoxicity in the rat: Role of vanilloid receptors and lipoxygenases
-
Veldhuis WB, van der Stelt M, Wadman MW, van Zadelhoff G, Maccarrone M, Fezza F, Veldink GA, Vliegenthart JF, Bar PR, Nicolay K, Di Marzo V (2003) Neuroprotection by the endogenous cannabinoid anandamide and arvanil against in vivo excitotoxicity in the rat: role of vanilloid receptors and lipoxygenases. J Neurosci 23:4127-4133
-
(2003)
J Neurosci
, vol.23
, pp. 4127-4133
-
-
Veldhuis, W.B.1
Van Der Stelt, M.2
Wadman, M.W.3
Van Zadelhoff, G.4
Maccarrone, M.5
Fezza, F.6
Veldink, G.A.7
Vliegenthart, J.F.8
Bar, P.R.9
Nicolay, K.10
Di Marzo, V.11
-
118
-
-
4344582253
-
Do cannabis-based medicinal extracts have general or specific effects on symptoms in multiple sclerosis? A double-blind, randomized, placebo-controlled study on 160 patients
-
Wade DT, Makela P, Robson P, House H, Bateman C (2004) Do cannabis-based medicinal extracts have general or specific effects on symptoms in multiple sclerosis? A double-blind, randomized, placebo-controlled study on 160 patients. Mult Scler 10:434-441
-
(2004)
Mult Scler
, vol.10
, pp. 434-441
-
-
Wade, D.T.1
Makela, P.2
Robson, P.3
House, H.4
Bateman, C.5
-
119
-
-
0031773354
-
Cardiovascular actions of cannabinoids and their generation during shock platelet- and macrophage-derived endogenous cannabinoids are involved in endotoxin-induced hypotension
-
Wagner JA, Varga K, Kunos G, Bridgen DT (1998) Cardiovascular actions of cannabinoids and their generation during shock platelet- and macrophage-derived endogenous cannabinoids are involved in endotoxin-induced hypotension. J Mol Med 76:824-836
-
(1998)
J Mol Med
, vol.76
, pp. 824-836
-
-
Wagner, J.A.1
Varga, K.2
Kunos, G.3
Bridgen, D.T.4
-
120
-
-
0035816432
-
Hemodynamic effects of cannabinoids: Coronary and cerebral vasodilation mediated by cannabinoid CB(1) receptors
-
Wagner JA, Jarai Z, Batkai S, Kunos G (2001) Hemodynamic effects of cannabinoids: coronary and cerebral vasodilation mediated by cannabinoid CB(1) receptors. Eur J Pharmacol 423:203-210
-
(2001)
Eur J Pharmacol
, vol.423
, pp. 203-210
-
-
Wagner, J.A.1
Jarai, Z.2
Batkai, S.3
Kunos, G.4
-
121
-
-
0032982520
-
The central cannabinoid receptor (CB1) mediates inhibition of nitric oxide production by rat microglial cells
-
Waksman Y, Olson JM, Carlisle SJ, Cabral GA (1999) The central cannabinoid receptor (CB1) mediates inhibition of nitric oxide production by rat microglial cells. J Pharmacol Exp Ther 288:1357-1366
-
(1999)
J Pharmacol Exp Ther
, vol.288
, pp. 1357-1366
-
-
Waksman, Y.1
Olson, J.M.2
Carlisle, S.J.3
Cabral, G.A.4
-
122
-
-
0035399346
-
Simultaneous measurement of anandamide and 2-arachidonoylglycerol by polymyxin B-selective adsorption and subsequent high-performance liquid chromatography analysis: Increase in endogenous cannabinoids in the sera of patients with endotoxic shock
-
Wang Y, Liu Y, Ito Y, Hashiguchi T, Kitajima I, Yamakuchi M, Shimizu H, Matsuo S, Imaizumi H, Maruyama I (2001) Simultaneous measurement of anandamide and 2-arachidonoylglycerol by polymyxin B-selective adsorption and subsequent high-performance liquid chromatography analysis: increase in endogenous cannabinoids in the sera of patients with endotoxic shock. Anal Biochem 294:73-82
-
(2001)
Anal Biochem
, vol.294
, pp. 73-82
-
-
Wang, Y.1
Liu, Y.2
Ito, Y.3
Hashiguchi, T.4
Kitajima, I.5
Yamakuchi, M.6
Shimizu, H.7
Matsuo, S.8
Imaizumi, H.9
Maruyama, I.10
-
123
-
-
0026046348
-
Influence of marijuana components (THC and CBD) on human mononuclear cell cytokine secretion in vitro
-
H Friedman, S Specter, TW Klein (eds) Plenum, New York
-
Watzl B, Scuderi P, Watson RR (1991) Influence of marijuana components (THC and CBD) on human mononuclear cell cytokine secretion in vitro. In: H Friedman, S Specter, TW Klein (eds) Advances in Experimental Medicine and Biology, Plenum, New York, pp 63-70.
-
(1991)
Advances in Experimental Medicine and Biology
, pp. 63-70
-
-
Watzl, B.1
Scuderi, P.2
Watson, R.R.3
-
124
-
-
0032160418
-
Differential blockade of the antinociceptive effects of centrally administered cannabinoids by SR141716A
-
Welch SP, Huffman JW, Lowe J (1998) Differential blockade of the antinociceptive effects of centrally administered cannabinoids by SR141716A. J Pharmacol Exp Ther 286:1301-1308
-
(1998)
J Pharmacol Exp Ther
, vol.286
, pp. 1301-1308
-
-
Welch, S.P.1
Huffman, J.W.2
Lowe, J.3
-
125
-
-
0028080884
-
Suppression of experimental autoimmune encephalomyelitis by cannabinoids
-
Wirguin I, Mechoulam R, Breuer A, Schezen E, Weidenfeld J, Brenner T (1994) Suppression of experimental autoimmune encephalomyelitis by cannabinoids. Immunopharmacology 28:209-214
-
(1994)
Immunopharmacology
, vol.28
, pp. 209-214
-
-
Wirguin, I.1
Mechoulam, R.2
Breuer, A.3
Schezen, E.4
Weidenfeld, J.5
Brenner, T.6
-
126
-
-
0026611540
-
9-Tetrahydrocannabinol suppresses concanavalin A induced increase in cytoplasmic free calcium in mouse thymocytes
-
9- Tetrahydrocannabinol suppresses concanavalin A induced increase in cytoplasmic free calcium in mouse thymocytes. Life Sci 51:151-160
-
(1992)
Life Sci
, vol.51
, pp. 151-160
-
-
Yebra, M.1
Klein, T.W.2
Friedman, H.3
-
128
-
-
0034235808
-
Δ-9-tetrahydrocannabinol inhibits antitumor immunity by a CB2 receptor-mediated, cytokine-dependent pathway
-
Zhu LX, Sharma S, Stolina M, Gardner B, Roth MD, Tashkin DP, Dubinett SM (2000) Δ-9-tetrahydrocannabinol inhibits antitumor immunity by a CB2 receptor-mediated, cytokine-dependent pathway. J Immunol 165:373-380
-
(2000)
J Immunol
, vol.165
, pp. 373-380
-
-
Zhu, L.X.1
Sharma, S.2
Stolina, M.3
Gardner, B.4
Roth, M.D.5
Tashkin, D.P.6
Dubinett, S.M.7
-
129
-
-
0031962165
-
Dimethylheptyl-THC-11 oic acid. A nonpsychoactive antiinflammatory agent with a cannabinoid template structure
-
Zurier RB, Rossetti RG, Lane JH, Goldberg JM, Hunter SA, Burstein SH (1998) Dimethylheptyl-THC-11 oic acid. A nonpsychoactive antiinflammatory agent with a cannabinoid template structure. Arthritis Rheum 41:163-170
-
(1998)
Arthritis Rheum
, vol.41
, pp. 163-170
-
-
Zurier, R.B.1
Rossetti, R.G.2
Lane, J.H.3
Goldberg, J.M.4
Hunter, S.A.5
Burstein, S.H.6
-
130
-
-
0037441413
-
Suppression of human monocyte interleukin-1beta production by ajulemic acid, a nonpsychoactive cannabinoid
-
Zurier RB, Rossetti RG, Burstein SH, Bidinger B (2003) Suppression of human monocyte interleukin-1beta production by ajulemic acid, a nonpsychoactive cannabinoid. Biochem Pharmacol 65:649-655
-
(2003)
Biochem Pharmacol
, vol.65
, pp. 649-655
-
-
Zurier, R.B.1
Rossetti, R.G.2
Burstein, S.H.3
Bidinger, B.4
-
131
-
-
0033614984
-
Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide
-
Zygmunt PM, Petersson J, Andersson DA, Chuang H, Sorgard M, Di Marzo V, Julius D, Hogestatt ED (1999) Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide. Nature 400:452-457
-
(1999)
Nature
, vol.400
, pp. 452-457
-
-
Zygmunt, P.M.1
Petersson, J.2
Andersson, D.A.3
Chuang, H.4
Sorgard, M.5
Di Marzo, V.6
Julius, D.7
Hogestatt, E.D.8
|