Modification of 5-HT2 receptor mediated behaviour in the rat by oleamide and the role of cannabinoid receptors

Neuropharmacology

Volumn 38, Issue 4, 1999, Pages 533-541

  Cheer, J F ^a   Cadogan, A K ^a   Marsden, C A ^a   Fone, K C F ^a   Kendall, D A ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

5 HT2 receptors; Cannabinoids; Cis 9,10 octadecenoamide; Oleamide

Indexed keywords

4 (1,1 DIMETHYLHEPTYL) 1',2',3',4',5',6' HEXAHYDRO 2,3' DIHYDROXY 6' (3 HYDROXYPROPYL)BIPHENYL; 4 IODO 2,5 DIMETHOXYAMPHETAMINE; CANNABINOID RECEPTOR; CANNABINOID RECEPTOR AGONIST; DEXANABINOL; OLEAMIDE; PHOSPHATIDYLINOSITIDE; RIMONABANT; SEROTONIN 2 RECEPTOR; SEROTONIN AGONIST; 4-IODO-2,5-DIMETHOXYPHENYLISOPROPYLAMINE; AMINO ACID RECEPTOR BLOCKING AGENT; AMPHETAMINE DERIVATIVE; CANNABINOID; CYCLOHEXANOL DERIVATIVE; DRUG DERIVATIVE; DRUG RECEPTOR; HYPNOTIC SEDATIVE AGENT; OLEIC ACID; OLEYLAMIDE; PHOSPHATIDYLINOSITOL; SEROTONIN; SEROTONIN 2A RECEPTOR; SEROTONIN RECEPTOR; TETRAHYDROCANNABINOL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BEHAVIOR; CONTROLLED STUDY; DRUG RECEPTOR BINDING; INTRAPERITONEAL DRUG ADMINISTRATION; LOCOMOTION; MALE; MUSCLE CONTRACTION; NONHUMAN; PRIORITY JOURNAL; RAT; WET DOG SHAKES; ANIMAL; ANIMAL BEHAVIOR; BRAIN CORTEX; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; MOTOR ACTIVITY; REFLEX; WISTAR RAT;

AMPHETAMINES; ANIMALS; BEHAVIOR, ANIMAL; CANNABINOIDS; CEREBRAL CORTEX; CYCLOHEXANOLS; EXCITATORY AMINO ACID ANTAGONISTS; HYPNOTICS AND SEDATIVES; MALE; MOTOR ACTIVITY; MUSCLE CONTRACTION; OLEIC ACIDS; PHOSPHATIDYLINOSITOLS; RATS; RATS, WISTAR; RECEPTOR, SEROTONIN, 5-HT2A; RECEPTORS, CANNABINOID; RECEPTORS, DRUG; RECEPTORS, SEROTONIN; REFLEX; SEROTONIN; SEROTONIN AGONISTS; TETRAHYDROCANNABINOL;

EID: 0032586854     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(98)00208-1     Document Type: Article

References (30)

1. Bedard P., Pycock C.J. 'Wet-Dog' shake behaviour in the rat: a possible quantitative model of central 5-hydroxytryptamine activity. Neuropharmacology. 16:1977;663-670.
2. Bisogno T., Sepe N., De Petrocellis L., Mechoulam R., Di Marzo V. The sleep-inducing factor oleamide is produced by mouse neuroblastoma cells. Biochem. Biophys. Res. Commun. 239:1997;473-479.
3. Boring D.L., Berglund B.A., Howlett A.C. Cerebrodiene, arachidonyl-ethanolamide and hybrid structures: potential for interaction with brain cannabinoid receptors. Prostaglandins Leukot. Essent. Fatty Acids. 55:1996;207-210.
4. Brown E., Kendall D.A., Nahorski S.R. Inositol phospholipid hydrolysis in rat cerebral cortical slices: I. receptor characterisation. J. Neurochem. 42:1984;1379-1387.
5. Cadogan A.-K., Fletcher C., Debank P., Marsden C.A., Kendall D.A. Differences in the in vivo effects of the endogenous sleep-inducing agent oleamide on 5-HT2 receptor function. Br. J. Pharmacol. 123:1998;247P.
6. Childers S.R., Sexton T., Roy M.B. Effects of anandamide on cannabinoid receptors in rat brain membranes. Biochem. Pharmacol. 47:1994;711-715.
7. 2B receptor signalling in the rat stomach fundus: dependence on calcium influx, calcium release and protein kinase C. Behav. Brain Res. 73:1996;289-292.
8. Cravatt B.F., Giang D.K., Mayfield S.P., Boger D.L., Lerner R.A., Gilula N.B. Molecular characterisation of an enzyme that degrades neuromodulatory fatty acid amides. Nature. 384:1996;83-87.
9. Cravatt B.F., Prospero-Garcia O., Siuzdak G., Gilula N.B., Henrikson S.J., Boger D.L., Lerner R.A. Chemical characterisation of a family of brain lipids that induce sleep. Science. 268:1995;1506-1509.
10. Devane W.A., Dysarz F.A., Johnson M.R., Melvin L.S., Howlett A.C. Determination and characterisation of a cannabinoid receptor in rat brain. Mol. Pharmacol. 34:1988;605-613.
11. 2 receptors in the behaviours produced by intrathecal administration of selected 5-HT agonists and the TRH analogue (CG 3509) to rats. Br. J. Pharmacol. 96:1989;599-608.
12. Fone K.C.F., Robinson A.J., Marsden C.A. Characterisation of the 5-HT receptor subtypes involved in the motor behaviours produced by intrathecal administration of 5-HT agonists in rats. Br. J. Pharmacol. 103:1991;1547-1555.
13. Giang D.K., Cravatt B.F. Molecular characterisation of human and mouse fatty acid amide hydrolases. Proc. Natl. Acad. Sci. USA. 94:1997;2238-2242.
14. Huidobro-Toro J.P., Harris R.A. Brain lipids that induce sleep are novel modulators of 5-hydroxytryptamine receptors. Proc. Natl. Acad. Sci. USA. 93:1996;8078-8082.
15. Kendall D.A., Nahorski S.R. 5-HT-stimulated inositol phospholipid hydrolysis in rat cerebral cortex slices: pharmacological characterisation and effects of antidepressants. J. Pharmacol. Exp. Therap. 233:1985;473-479.
16. 35S]thio)-triphosphate binding assay in rat cerebellar membranes. J. Pharmacol. Exp. Therap. 285:1998;553-560.
17. Hoyer D., Clarke D.E., Fozard J.R., Hartig P.R., Mylecharane E.J., Saxena P.R., Humphrey P.P.A. VII International union of pharmacology classification of receptors for 5-hydroxytryptamine. Pharmacol. Rev. 46:1994;157-203.
18. Langstein J., Hofstadter F., Schwarz H. Cis-9,10-octadecenoamide an endogenous sleep-inducing CNS compound inhibits lymphocyte proliferation. Res. Immunol. 147:1996;389-396.
19. A receptors and inhibitory synaptic currents by the endogenous CNS sleep regulator cis-9,10-octadecenoamide (cOA). Br. J. Pharmacol. 124:1998;873-882.
20. Maurelli S., Bisogno T., De Petrocellis L., Di Luccia A., Marino G., Di Marzo V. Two novel classes of neuroactive fatty acid amides are substrates for mouse neuroblastoma anandamide amidohydrolase. FEBS Lett. 377:1995;82-86.
21. Mechoulam R., Fride E., Hanus L., Sheskin T., Bisogno T., Di Marzo V., Bayewitch M., Vogel Z. Anandamide may mediate sleep induction. Nature. 389:1997;25-26.
22. Mechoulam R., Feigenbaum J.J., Lander N., Segal M., Jarbe T.U.C., Hiltunen A.J., Consroe P. Enantiomeric cannabinoids: stereospecificity of psychotropic activity. Experientia. 44:1988;762-764.
23. Merkler D.J., Merkler K.A., Stern W., Fleming F.F. Fatty acid amide biosynthesis:a possible role for peptidylglycine α-amidating enzyme and acyl-coenzyme A: glycine N-acyltransferase. Arch. Biochem. Biophys. 330:1996;430-434.
24. 2 receptor-mediated head shakes but not brain c-fos induction. Neuropharmacology. 35:1996;303-313.
25. Petitet F., Jeantaud B., Capet M., Doble A. Interaction of brain cannabinoid receptors with guanine nucleotide binding protein, a radioligand binding study. Biochem. Pharmacol. 54:1997;1267-1270.
26. Rinaldi-Carmona M., Barth F., Heauleme M. et al. SR141716A a potent and selective antagonist of the brain cannabinoid receptor. FEBS Lett. 350:1994;240-244.
27. 2B serotonin receptor. FEBS Lett. 342:1994;85-90.
28. Sugiura T., Kondo S., Kodaka T., Tonegawa T., Nakane S., Yamashita A., Ishima Y., Waku K. Enzymatic synthesis of oleamide (cis-9,10-octadecenoamide), sleep inducing lipid, by rat brain microsomes. Biochem. Molec. Biol. Int. 40:1996;931-938.
29. Thomas E.A., Carson M.J., Neal M.J., Sutcliffe J.G. Unique allosteric regulation of 5-hydroxytryptamine receptor-mediated signal transduction by oleamide. Proc. Natl. Acad. Sci. USA. 94:1997;14115-14119.
30. 2B receptor mediated calcium release from ryanodine sensitive intracellular stores in human pulmonary artery endothelial cells. Br. J. Pharmacol. 117:1996;993-994.