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Volumn 16, Issue 4, 2016, Pages e47-e63

Host-directed therapies for infectious diseases: Current status, recent progress, and future prospects

(13)  Zumla, Alimuddin a,b   Rao, Martin c,d   Wallis, Robert S e   Kaufmann, Stefan H E f   Rustomjee, Roxana g   Mwaba, Peter h,i   Vilaplana, Cris j   Yeboah Manu, Dorothy k   Chakaya, Jeremiah l   Ippolito, Giuseppe m   Azhar, Esam n   Hoelscher, Michael o,p   Maeurer, Markus c,d  


Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; BIOLOGICAL PRODUCT; IMMUNOMODULATING AGENT; CYTOKINE; MONOCLONAL ANTIBODY; VITAMIN;

EID: 84962538329     PISSN: 14733099     EISSN: 14744457     Source Type: Journal    
DOI: 10.1016/S1473-3099(16)00078-5     Document Type: Review
Times cited : (265)

References (174)
  • 1
    • 84920703518 scopus 로고    scopus 로고
    • Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013
    • GBD 2013 Mortality and Causes of Death Collaborators
    • Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet 2015, 385:117-171. GBD 2013 Mortality and Causes of Death Collaborators.
    • (2015) Lancet , vol.385 , pp. 117-171
  • 2
    • 84858381864 scopus 로고    scopus 로고
    • Modulating immunity as a therapy for bacterial infections
    • Hancock RE, Nijnik A, Philpott DJ Modulating immunity as a therapy for bacterial infections. Nat Rev Microbiol 2012, 10:243-254.
    • (2012) Nat Rev Microbiol , vol.10 , pp. 243-254
    • Hancock, R.E.1    Nijnik, A.2    Philpott, D.J.3
  • 3
    • 84928423838 scopus 로고    scopus 로고
    • Adjunct prednisone therapy for patients with community-acquired pneumonia: a multicentre, double-blind, randomised, placebo-controlled trial
    • Blum CA, Nigro N, Briel M, et al. Adjunct prednisone therapy for patients with community-acquired pneumonia: a multicentre, double-blind, randomised, placebo-controlled trial. Lancet 2015, 385:1511-1518.
    • (2015) Lancet , vol.385 , pp. 1511-1518
    • Blum, C.A.1    Nigro, N.2    Briel, M.3
  • 4
    • 34249304464 scopus 로고    scopus 로고
    • Combination antibiotic therapy improves survival in patients with community-acquired pneumonia and shock
    • the CAPUCI Study Group
    • Rodríguez A, Mendia A, Sirvent JM, et al. Combination antibiotic therapy improves survival in patients with community-acquired pneumonia and shock. Crit Care Med 2007, 35:1493-1498. the CAPUCI Study Group.
    • (2007) Crit Care Med , vol.35 , pp. 1493-1498
    • Rodríguez, A.1    Mendia, A.2    Sirvent, J.M.3
  • 5
    • 0023127708 scopus 로고
    • Effect of indomethacin on arterial oxygenation in critically ill patients with severe bacterial pneumonia
    • Hanly PJ, Roberts D, Dobson K, Light RB Effect of indomethacin on arterial oxygenation in critically ill patients with severe bacterial pneumonia. Lancet 1987, 1:351-354.
    • (1987) Lancet , vol.1 , pp. 351-354
    • Hanly, P.J.1    Roberts, D.2    Dobson, K.3    Light, R.B.4
  • 6
    • 0030899316 scopus 로고    scopus 로고
    • Effect of acetylsalicylic acid on pulmonary gas exchange in patients with severe pneumonia: a pilot study
    • Ferrer M, Torres A, Baer R, Hernández C, Roca J, Rodriguez-Roisin R Effect of acetylsalicylic acid on pulmonary gas exchange in patients with severe pneumonia: a pilot study. Chest 1997, 111:1094-1100.
    • (1997) Chest , vol.111 , pp. 1094-1100
    • Ferrer, M.1    Torres, A.2    Baer, R.3    Hernández, C.4    Roca, J.5    Rodriguez-Roisin, R.6
  • 7
    • 8044246571 scopus 로고    scopus 로고
    • The effects of ibuprofen on the physiology and survival of patients with sepsis
    • the Ibuprofen in Sepsis Study Group
    • Bernard GR, Wheeler AP, Russell JA, et al. The effects of ibuprofen on the physiology and survival of patients with sepsis. N Engl J Med 1997, 336:912-918. the Ibuprofen in Sepsis Study Group.
    • (1997) N Engl J Med , vol.336 , pp. 912-918
    • Bernard, G.R.1    Wheeler, A.P.2    Russell, J.A.3
  • 8
    • 33750958903 scopus 로고    scopus 로고
    • Statins and outcomes in patients admitted to hospital with community acquired pneumonia: population based prospective cohort study
    • Majumdar SR, McAlister FA, Eurich DT, Padwal RS, Marrie TJ Statins and outcomes in patients admitted to hospital with community acquired pneumonia: population based prospective cohort study. BMJ 2006, 333:999.
    • (2006) BMJ , vol.333 , pp. 999
    • Majumdar, S.R.1    McAlister, F.A.2    Eurich, D.T.3    Padwal, R.S.4    Marrie, T.J.5
  • 9
    • 42949123466 scopus 로고    scopus 로고
    • Impact of statins and angiotensin-converting enzyme inhibitors on mortality of subjects hospitalised with pneumonia
    • Mortensen EM, Pugh MJ, Copeland LA, et al. Impact of statins and angiotensin-converting enzyme inhibitors on mortality of subjects hospitalised with pneumonia. Eur Respir J 2008, 31:611-617.
    • (2008) Eur Respir J , vol.31 , pp. 611-617
    • Mortensen, E.M.1    Pugh, M.J.2    Copeland, L.A.3
  • 10
    • 33847321185 scopus 로고    scopus 로고
    • Statins and the risk of pneumonia: a population-based, nested case-control study
    • Schlienger RG, Fedson DS, Jick SS, Jick H, Meier CR Statins and the risk of pneumonia: a population-based, nested case-control study. Pharmacotherapy 2007, 27:325-332.
    • (2007) Pharmacotherapy , vol.27 , pp. 325-332
    • Schlienger, R.G.1    Fedson, D.S.2    Jick, S.S.3    Jick, H.4    Meier, C.R.5
  • 11
    • 26244441019 scopus 로고    scopus 로고
    • The effect of prior statin use on 30-day mortality for patients hospitalized with community-acquired pneumonia
    • Mortensen EM, Restrepo MI, Anzueto A, Pugh J The effect of prior statin use on 30-day mortality for patients hospitalized with community-acquired pneumonia. Respir Res 2005, 6:82.
    • (2005) Respir Res , vol.6 , pp. 82
    • Mortensen, E.M.1    Restrepo, M.I.2    Anzueto, A.3    Pugh, J.4
  • 12
    • 34247209763 scopus 로고    scopus 로고
    • Influenza and COPD mortality protection as pleiotropic, dose-dependent effects of statins
    • Frost FJ, Petersen H, Tollestrup K, Skipper B Influenza and COPD mortality protection as pleiotropic, dose-dependent effects of statins. Chest 2007, 131:1006-1012.
    • (2007) Chest , vol.131 , pp. 1006-1012
    • Frost, F.J.1    Petersen, H.2    Tollestrup, K.3    Skipper, B.4
  • 13
    • 54349122201 scopus 로고    scopus 로고
    • Prior statin use is associated with improved outcomes in community-acquired pneumonia
    • 07.e1
    • Chalmers JD, Singanayagam A, Murray MP, Hill AT Prior statin use is associated with improved outcomes in community-acquired pneumonia. Am J Med 2008, 121:1002. 07.e1.
    • (2008) Am J Med , vol.121 , pp. 1002
    • Chalmers, J.D.1    Singanayagam, A.2    Murray, M.P.3    Hill, A.T.4
  • 14
    • 54949095097 scopus 로고    scopus 로고
    • Preadmission use of statins and outcomes after hospitalization with pneumonia: population-based cohort study of 29900 patients
    • Thomsen RW, Riis A, Kornum JB, Christensen S, Johnsen SP, Sørensen HT Preadmission use of statins and outcomes after hospitalization with pneumonia: population-based cohort study of 29900 patients. Arch Intern Med 2008, 168:2081-2087.
    • (2008) Arch Intern Med , vol.168 , pp. 2081-2087
    • Thomsen, R.W.1    Riis, A.2    Kornum, J.B.3    Christensen, S.4    Johnsen, S.P.5    Sørensen, H.T.6
  • 15
  • 16
    • 33645826944 scopus 로고    scopus 로고
    • Statin use and mortality within 180 days after bacteremia: a population-based cohort study
    • Thomsen RW, Hundborg HH, Johnsen SP, et al. Statin use and mortality within 180 days after bacteremia: a population-based cohort study. Crit Care Med 2006, 34:1080-1086.
    • (2006) Crit Care Med , vol.34 , pp. 1080-1086
    • Thomsen, R.W.1    Hundborg, H.H.2    Johnsen, S.P.3
  • 17
    • 65449189768 scopus 로고    scopus 로고
    • Risk of community-acquired pneumonia and the use of statins, ace inhibitors and gastric acid suppressants: a population-based case-control study
    • Myles PR, Hubbard RB, McKeever TM, Pogson Z, Smith CJ, Gibson JE Risk of community-acquired pneumonia and the use of statins, ace inhibitors and gastric acid suppressants: a population-based case-control study. Pharmacoepidemiol Drug Saf 2009, 18:269-275.
    • (2009) Pharmacoepidemiol Drug Saf , vol.18 , pp. 269-275
    • Myles, P.R.1    Hubbard, R.B.2    McKeever, T.M.3    Pogson, Z.4    Smith, C.J.5    Gibson, J.E.6
  • 18
    • 79953905093 scopus 로고    scopus 로고
    • Effect of statin treatment on short term mortality after pneumonia episode: cohort study
    • Douglas I, Evans S, Smeeth L Effect of statin treatment on short term mortality after pneumonia episode: cohort study. BMJ 2011, 342:d1642.
    • (2011) BMJ , vol.342 , pp. d1642
    • Douglas, I.1    Evans, S.2    Smeeth, L.3
  • 19
    • 79961024148 scopus 로고    scopus 로고
    • Understanding the potential role of statins in pneumonia and sepsis
    • Yende S, Milbrandt EB, Kellum JA, et al. Understanding the potential role of statins in pneumonia and sepsis. Crit Care Med 2011, 39:1871-1878.
    • (2011) Crit Care Med , vol.39 , pp. 1871-1878
    • Yende, S.1    Milbrandt, E.B.2    Kellum, J.A.3
  • 20
    • 84887306849 scopus 로고    scopus 로고
    • Glyburide reduces bacterial dissemination in a mouse model of melioidosis
    • Koh GC, Weehuizen TA, Breitbach K, et al. Glyburide reduces bacterial dissemination in a mouse model of melioidosis. PLoS Negl Trop Dis 2013, 7:e2500.
    • (2013) PLoS Negl Trop Dis , vol.7 , pp. e2500
    • Koh, G.C.1    Weehuizen, T.A.2    Breitbach, K.3
  • 21
    • 80053428072 scopus 로고    scopus 로고
    • Toll-like receptor 2 mediates fatal immunopathology in mice during treatment of secondary pneumococcal pneumonia following influenza
    • Karlström A, Heston SM, Boyd KL, Tuomanen EI, McCullers JA Toll-like receptor 2 mediates fatal immunopathology in mice during treatment of secondary pneumococcal pneumonia following influenza. J Infect Dis 2011, 204:1358-1366.
    • (2011) J Infect Dis , vol.204 , pp. 1358-1366
    • Karlström, A.1    Heston, S.M.2    Boyd, K.L.3    Tuomanen, E.I.4    McCullers, J.A.5
  • 22
    • 0034890569 scopus 로고    scopus 로고
    • Monotherapy may be suboptimal for severe bacteremic pneumococcal pneumonia
    • Waterer GW, Somes GW, Wunderink RG Monotherapy may be suboptimal for severe bacteremic pneumococcal pneumonia. Arch Intern Med 2001, 161:1837-1842.
    • (2001) Arch Intern Med , vol.161 , pp. 1837-1842
    • Waterer, G.W.1    Somes, G.W.2    Wunderink, R.G.3
  • 23
    • 19944429796 scopus 로고    scopus 로고
    • Clinical characteristics at initial presentation and impact of dual therapy on the outcome of bacteremic Streptococcus pneumoniae pneumonia in adults
    • Weiss K, Low DE, Cortes L, et al. Clinical characteristics at initial presentation and impact of dual therapy on the outcome of bacteremic Streptococcus pneumoniae pneumonia in adults. Can Respir J 2004, 11:589-593.
    • (2004) Can Respir J , vol.11 , pp. 589-593
    • Weiss, K.1    Low, D.E.2    Cortes, L.3
  • 25
    • 0033606799 scopus 로고    scopus 로고
    • Bacteremic pneumococcal pneumonia in one American City: a 20-year longitudinal study, 1978-1997
    • Mufson MA, Stanek RJ Bacteremic pneumococcal pneumonia in one American City: a 20-year longitudinal study, 1978-1997. Am J Med 1999, 107:34S-43S.
    • (1999) Am J Med , vol.107 , pp. 34S-43S
    • Mufson, M.A.1    Stanek, R.J.2
  • 26
    • 0037442372 scopus 로고    scopus 로고
    • Addition of a macrolide to a β-lactam-based empirical antibiotic regimen is associated with lower in-hospital mortality for patients with bacteremic pneumococcal pneumonia
    • Martinez JA, Horcajada JP, Almela M, et al. Addition of a macrolide to a β-lactam-based empirical antibiotic regimen is associated with lower in-hospital mortality for patients with bacteremic pneumococcal pneumonia. Clin Infect Dis 2003, 36:389-395.
    • (2003) Clin Infect Dis , vol.36 , pp. 389-395
    • Martinez, J.A.1    Horcajada, J.P.2    Almela, M.3
  • 27
    • 4544244010 scopus 로고    scopus 로고
    • Combination antibiotic therapy lowers mortality among severely ill patients with pneumococcal bacteremia
    • the International Pneumococcal Study Group
    • Baddour LM, Yu VL, Klugman KP, et al. Combination antibiotic therapy lowers mortality among severely ill patients with pneumococcal bacteremia. Am J Respir Crit Care Med 2004, 170:440-444. the International Pneumococcal Study Group.
    • (2004) Am J Respir Crit Care Med , vol.170 , pp. 440-444
    • Baddour, L.M.1    Yu, V.L.2    Klugman, K.P.3
  • 28
    • 33751039945 scopus 로고    scopus 로고
    • Impact of initial antibiotic choice on mortality from pneumococcal pneumonia
    • the Pneumococcal Pneumonia in Spain Study Group
    • Aspa J, Rajas O, Rodriguez de Castro F, et al. Impact of initial antibiotic choice on mortality from pneumococcal pneumonia. Eur Respir J 2006, 27:1010-1019. the Pneumococcal Pneumonia in Spain Study Group.
    • (2006) Eur Respir J , vol.27 , pp. 1010-1019
    • Aspa, J.1    Rajas, O.2    Rodriguez de Castro, F.3
  • 29
    • 27944446850 scopus 로고    scopus 로고
    • Lack of effect of combination antibiotic therapy on mortality in patients with pneumococcal sepsis
    • Harbarth S, Garbino J, Pugin J, Romand JA, Pittet D Lack of effect of combination antibiotic therapy on mortality in patients with pneumococcal sepsis. Eur J Clin Microbiol Infect Dis 2005, 24:688-690.
    • (2005) Eur J Clin Microbiol Infect Dis , vol.24 , pp. 688-690
    • Harbarth, S.1    Garbino, J.2    Pugin, J.3    Romand, J.A.4    Pittet, D.5
  • 30
    • 33747346508 scopus 로고    scopus 로고
    • Addition of a macrolide to an β-lactam in bacteremic pneumococcal pneumonia
    • Dwyer R, Ortqvist A, Aufwerber E, et al. Addition of a macrolide to an β-lactam in bacteremic pneumococcal pneumonia. Eur J Clin Microbiol Infect Dis 2006, 25:518-521.
    • (2006) Eur J Clin Microbiol Infect Dis , vol.25 , pp. 518-521
    • Dwyer, R.1    Ortqvist, A.2    Aufwerber, E.3
  • 31
    • 0037541094 scopus 로고    scopus 로고
    • Impact of initial antibiotic choice on clinical outcomes in community-acquired pneumonia: analysis of a hospital claims-made database
    • Brown RB, Iannini P, Gross P, Kunkel M Impact of initial antibiotic choice on clinical outcomes in community-acquired pneumonia: analysis of a hospital claims-made database. Chest 2003, 123:1503-1511.
    • (2003) Chest , vol.123 , pp. 1503-1511
    • Brown, R.B.1    Iannini, P.2    Gross, P.3    Kunkel, M.4
  • 32
    • 33847173420 scopus 로고    scopus 로고
    • Antibiotics for bacteremic pneumonia: improved outcomes with macrolides but not fluoroquinolones
    • Metersky ML, Ma A, Houck PM, Bratzler DW Antibiotics for bacteremic pneumonia: improved outcomes with macrolides but not fluoroquinolones. Chest 2007, 131:466-473.
    • (2007) Chest , vol.131 , pp. 466-473
    • Metersky, M.L.1    Ma, A.2    Houck, P.M.3    Bratzler, D.W.4
  • 33
    • 78049354889 scopus 로고    scopus 로고
    • Helicobacter pylori and gastric cancer: factors that modulate disease risk
    • Wroblewski LE, Peek RM, Wilson KT Helicobacter pylori and gastric cancer: factors that modulate disease risk. Clin Microbiol Rev 2010, 23:713-739.
    • (2010) Clin Microbiol Rev , vol.23 , pp. 713-739
    • Wroblewski, L.E.1    Peek, R.M.2    Wilson, K.T.3
  • 34
    • 84890883299 scopus 로고    scopus 로고
    • Helicobacter pylori induces increased expression of the vitamin D receptor in immune responses
    • Guo L, Chen W, Zhu H, et al. Helicobacter pylori induces increased expression of the vitamin D receptor in immune responses. Helicobacter 2014, 19:37-47.
    • (2014) Helicobacter , vol.19 , pp. 37-47
    • Guo, L.1    Chen, W.2    Zhu, H.3
  • 35
    • 84930339698 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate receptor agonism reduces Bordetella pertussis-mediated-lung pathology
    • Skerry C, Scanlon K, Rosen H, Carbonetti NH Sphingosine-1-phosphate receptor agonism reduces Bordetella pertussis-mediated-lung pathology. J Infect Dis 2015, 211:1883-1886.
    • (2015) J Infect Dis , vol.211 , pp. 1883-1886
    • Skerry, C.1    Scanlon, K.2    Rosen, H.3    Carbonetti, N.H.4
  • 36
    • 33845982233 scopus 로고    scopus 로고
    • Is pertussis immune globulin efficacious for the treatment of hospitalized infants with pertussis? No answer yet
    • the Pediatric Investigators Collaborative Network on Infections in Canada
    • Halperin SA, Vaudry W, Boucher FD, Mackintosh K, Waggener TB, Smith B Is pertussis immune globulin efficacious for the treatment of hospitalized infants with pertussis? No answer yet. Pediatr Infect Dis J 2007, 26:79-81. the Pediatric Investigators Collaborative Network on Infections in Canada.
    • (2007) Pediatr Infect Dis J , vol.26 , pp. 79-81
    • Halperin, S.A.1    Vaudry, W.2    Boucher, F.D.3    Mackintosh, K.4    Waggener, T.B.5    Smith, B.6
  • 37
    • 84966468439 scopus 로고    scopus 로고
    • Novel therapies for the treatment of pertussis disease
    • ftv074
    • Scanlon KM, Skerry C, Carbonetti NH Novel therapies for the treatment of pertussis disease. Pathog Dis 2015, 73:ftv074.
    • (2015) Pathog Dis , vol.73
    • Scanlon, K.M.1    Skerry, C.2    Carbonetti, N.H.3
  • 38
    • 0032810796 scopus 로고    scopus 로고
    • Protective effects of pertussis immunoglobulin (P-IGIV) in the aerosol challenge model
    • Bruss JB, Siber GR Protective effects of pertussis immunoglobulin (P-IGIV) in the aerosol challenge model. Clin Diagn Lab Immunol 1999, 6:464-470.
    • (1999) Clin Diagn Lab Immunol , vol.6 , pp. 464-470
    • Bruss, J.B.1    Siber, G.R.2
  • 39
    • 84962580998 scopus 로고    scopus 로고
    • Augmentation of cationic antimicrobial peptide production with histone deacetylase inhibitors as a novel epigenetic therapy for bacterial infections
    • Yedery R, Jerse A Augmentation of cationic antimicrobial peptide production with histone deacetylase inhibitors as a novel epigenetic therapy for bacterial infections. Antibiotics 2015, 4:44-61.
    • (2015) Antibiotics , vol.4 , pp. 44-61
    • Yedery, R.1    Jerse, A.2
  • 40
    • 84962529619 scopus 로고    scopus 로고
    • Host-directed therapeutics as adjunctive therapy for antibiotic-resistant Neisseria gonorrhoeae
    • asbtr 38.
    • Leduc I, Jerse A Host-directed therapeutics as adjunctive therapy for antibiotic-resistant Neisseria gonorrhoeae. Sex Transm Infect 2015, 91(suppl 2). asbtr 38.
    • (2015) Sex Transm Infect , vol.91
    • Leduc, I.1    Jerse, A.2
  • 41
    • 2942586974 scopus 로고    scopus 로고
    • Coaxing HIV-1 from resting CD4 T cells: histone deacetylase inhibition allows latent viral expression
    • Ylisastigui L, Archin NM, Lehrman G, Bosch RJ, Margolis DM Coaxing HIV-1 from resting CD4 T cells: histone deacetylase inhibition allows latent viral expression. AIDS 2004, 18:1101-1108.
    • (2004) AIDS , vol.18 , pp. 1101-1108
    • Ylisastigui, L.1    Archin, N.M.2    Lehrman, G.3    Bosch, R.J.4    Margolis, D.M.5
  • 42
    • 84978328043 scopus 로고    scopus 로고
    • Activation of latent human immunodeficiency virus by the histone deacetylase inhibitor panobinostat: a pilot study to assess effects on the central nervous system
    • ofv037
    • Rasmussen TA, Tolstrup M, Moller HJ, et al. Activation of latent human immunodeficiency virus by the histone deacetylase inhibitor panobinostat: a pilot study to assess effects on the central nervous system. Open Forum Infect Dis 2015, 2:ofv037.
    • (2015) Open Forum Infect Dis , vol.2
    • Rasmussen, T.A.1    Tolstrup, M.2    Moller, H.J.3
  • 43
    • 79957934393 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors for purging HIV-1 from the latent reservoir
    • Matalon S, Rasmussen TA, Dinarello CA Histone deacetylase inhibitors for purging HIV-1 from the latent reservoir. Mol Med 2011, 17:466-472.
    • (2011) Mol Med , vol.17 , pp. 466-472
    • Matalon, S.1    Rasmussen, T.A.2    Dinarello, C.A.3
  • 44
    • 33748947326 scopus 로고    scopus 로고
    • PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression
    • Day CL, Kaufmann DE, Kiepiela P, et al. PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression. Nature 2006, 443:350-354.
    • (2006) Nature , vol.443 , pp. 350-354
    • Day, C.L.1    Kaufmann, D.E.2    Kiepiela, P.3
  • 45
    • 84924101732 scopus 로고    scopus 로고
    • Role of PD-1 co-inhibitory pathway in HIV infection and potential therapeutic options
    • Velu V, Shetty RD, Larsson M, Shankar EM Role of PD-1 co-inhibitory pathway in HIV infection and potential therapeutic options. Retrovirology 2015, 12:14.
    • (2015) Retrovirology , vol.12 , pp. 14
    • Velu, V.1    Shetty, R.D.2    Larsson, M.3    Shankar, E.M.4
  • 46
    • 33749338938 scopus 로고    scopus 로고
    • PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infection
    • Petrovas C, Casazza JP, Brenchley JM, et al. PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infection. J Exp Med 2006, 203:2281-2292.
    • (2006) J Exp Med , vol.203 , pp. 2281-2292
    • Petrovas, C.1    Casazza, J.P.2    Brenchley, J.M.3
  • 47
    • 84879105636 scopus 로고    scopus 로고
    • Safety and immunological responses to human mesenchymal stem cell therapy in difficult-to-treat HIV-1-infected patients
    • Zhang Z, Fu J, Xu X, et al. Safety and immunological responses to human mesenchymal stem cell therapy in difficult-to-treat HIV-1-infected patients. AIDS 2013, 27:1283-1293.
    • (2013) AIDS , vol.27 , pp. 1283-1293
    • Zhang, Z.1    Fu, J.2    Xu, X.3
  • 48
    • 84887821770 scopus 로고    scopus 로고
    • Infusion of donor-derived CD19-redirected virus-specific T cells for B-cell malignancies relapsed after allogeneic stem cell transplant: a phase 1 study
    • Cruz CR, Micklethwaite KP, Savoldo B, et al. Infusion of donor-derived CD19-redirected virus-specific T cells for B-cell malignancies relapsed after allogeneic stem cell transplant: a phase 1 study. Blood 2013, 122:2965-2973.
    • (2013) Blood , vol.122 , pp. 2965-2973
    • Cruz, C.R.1    Micklethwaite, K.P.2    Savoldo, B.3
  • 49
    • 84887501471 scopus 로고    scopus 로고
    • Safety and clinical efficacy of rapidly-generated trivirus-directed T cells as treatment for adenovirus, EBV, and CMV infections after allogeneic hematopoietic stem cell transplant
    • Gerdemann U, Katari UL, Papadopoulou A, et al. Safety and clinical efficacy of rapidly-generated trivirus-directed T cells as treatment for adenovirus, EBV, and CMV infections after allogeneic hematopoietic stem cell transplant. Mol Ther 2013, 21:2113-2121.
    • (2013) Mol Ther , vol.21 , pp. 2113-2121
    • Gerdemann, U.1    Katari, U.L.2    Papadopoulou, A.3
  • 50
    • 84866645392 scopus 로고    scopus 로고
    • Rapid salvage treatment with virus-specific T cells for therapy-resistant disease
    • Uhlin M, Gertow J, Uzunel M, et al. Rapid salvage treatment with virus-specific T cells for therapy-resistant disease. Clin Infect Dis 2012, 55:1064-1073.
    • (2012) Clin Infect Dis , vol.55 , pp. 1064-1073
    • Uhlin, M.1    Gertow, J.2    Uzunel, M.3
  • 51
    • 84943409072 scopus 로고    scopus 로고
    • T-cell therapy: options for infectious diseases
    • Parida SK, Poiret T, Zhenjiang L, et al. T-cell therapy: options for infectious diseases. Clin Infect Dis 2015, 61(suppl 3):S217-S224.
    • (2015) Clin Infect Dis , vol.61 , pp. S217-S224
    • Parida, S.K.1    Poiret, T.2    Zhenjiang, L.3
  • 52
    • 77952946091 scopus 로고    scopus 로고
    • Use of cytomegalovirus intravenous immune globulin for the adjunctive treatment of cytomegalovirus in hematopoietic stem cell transplant recipients
    • Alexander BT, Hladnik LM, Augustin KM, et al. Use of cytomegalovirus intravenous immune globulin for the adjunctive treatment of cytomegalovirus in hematopoietic stem cell transplant recipients. Pharmacotherapy 2010, 30:554-561.
    • (2010) Pharmacotherapy , vol.30 , pp. 554-561
    • Alexander, B.T.1    Hladnik, L.M.2    Augustin, K.M.3
  • 53
    • 84887606007 scopus 로고    scopus 로고
    • Cytomegalovirus diseases after hematopoietic stem cell transplantation: a mini-review
    • Ariza-Heredia EJ, Nesher L, Chemaly RF Cytomegalovirus diseases after hematopoietic stem cell transplantation: a mini-review. Cancer Lett 2014, 342:1-8.
    • (2014) Cancer Lett , vol.342 , pp. 1-8
    • Ariza-Heredia, E.J.1    Nesher, L.2    Chemaly, R.F.3
  • 54
    • 70350560649 scopus 로고    scopus 로고
    • Generation of HCMV-specific T-cell lines from seropositive solid-organ-transplant recipients for adoptive T-cell therapy
    • Brestrich G, Zwinger S, Roemhild A, et al. Generation of HCMV-specific T-cell lines from seropositive solid-organ-transplant recipients for adoptive T-cell therapy. J Immunother 2009, 32:932-940.
    • (2009) J Immunother , vol.32 , pp. 932-940
    • Brestrich, G.1    Zwinger, S.2    Roemhild, A.3
  • 55
    • 4544261298 scopus 로고    scopus 로고
    • Treatment of adenovirus infections in the immunocompromised host
    • Ljungman P Treatment of adenovirus infections in the immunocompromised host. Eur J Clin Microbiol Infect Dis 2004, 23:583-588.
    • (2004) Eur J Clin Microbiol Infect Dis , vol.23 , pp. 583-588
    • Ljungman, P.1
  • 56
    • 84961171885 scopus 로고    scopus 로고
    • Oliveira KG, Malta FM, Nastri AC, et al. Increased hepatic expression of miRNA-122 in patients infected with HCV genotype 3. Med Microbiol Immunol 2015, published online Aug 14. 10.1007/S00430-015-0431-0.
  • 57
    • 84920116302 scopus 로고    scopus 로고
    • In vitro antiviral activity and preclinical and clinical resistance profile of miravirsen, a novel anti-hepatitis C virus therapeutic targeting the human factor miR-122
    • Ottosen S, Parsley TB, Yang L, et al. In vitro antiviral activity and preclinical and clinical resistance profile of miravirsen, a novel anti-hepatitis C virus therapeutic targeting the human factor miR-122. Antimicrob Agents Chemother 2015, 59:599-608.
    • (2015) Antimicrob Agents Chemother , vol.59 , pp. 599-608
    • Ottosen, S.1    Parsley, T.B.2    Yang, L.3
  • 59
    • 84941877077 scopus 로고    scopus 로고
    • Management of patients with familial hypercholesterolaemia
    • Reiner Ž Management of patients with familial hypercholesterolaemia. Nat Rev Cardiol 2015, 12:565-575.
    • (2015) Nat Rev Cardiol , vol.12 , pp. 565-575
    • Reiner, Ž.1
  • 60
    • 84878089612 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled assessment of BMS-936558, a fully human monoclonal antibody to programmed death-1 (PD-1), in patients with chronic hepatitis C virus infection
    • Gardiner D, Lalezari J, Lawitz E, et al. A randomized, double-blind, placebo-controlled assessment of BMS-936558, a fully human monoclonal antibody to programmed death-1 (PD-1), in patients with chronic hepatitis C virus infection. PLoS One 2013, 8:e63818.
    • (2013) PLoS One , vol.8 , pp. e63818
    • Gardiner, D.1    Lalezari, J.2    Lawitz, E.3
  • 61
    • 75749146715 scopus 로고    scopus 로고
    • Pegylated interferons for the treatment of chronic hepatitis C: pharmacological and clinical differences between peginterferon-alpha-2a and peginterferon-alpha-2b
    • Foster GR Pegylated interferons for the treatment of chronic hepatitis C: pharmacological and clinical differences between peginterferon-alpha-2a and peginterferon-alpha-2b. Drugs 2010, 70:147-165.
    • (2010) Drugs , vol.70 , pp. 147-165
    • Foster, G.R.1
  • 62
    • 84882370432 scopus 로고    scopus 로고
    • Treating influenza with statins and other immunomodulatory agents
    • Fedson DS Treating influenza with statins and other immunomodulatory agents. Antiviral Res 2013, 99:417-435.
    • (2013) Antiviral Res , vol.99 , pp. 417-435
    • Fedson, D.S.1
  • 63
    • 67649126476 scopus 로고    scopus 로고
    • Confronting the next influenza pandemic with anti-inflammatory and immunomodulatory agents: why they are needed and how they might work
    • Fedson DS Confronting the next influenza pandemic with anti-inflammatory and immunomodulatory agents: why they are needed and how they might work. Influenza Other Respi Viruses 2009, 3:129-142.
    • (2009) Influenza Other Respi Viruses , vol.3 , pp. 129-142
    • Fedson, D.S.1
  • 64
    • 84555195641 scopus 로고    scopus 로고
    • Association between use of statins and mortality among patients hospitalized with laboratory-confirmed influenza virus infections: a multistate study
    • Vandermeer ML, Thomas AR, Kamimoto L, et al. Association between use of statins and mortality among patients hospitalized with laboratory-confirmed influenza virus infections: a multistate study. J Infect Dis 2012, 205:13-19.
    • (2012) J Infect Dis , vol.205 , pp. 13-19
    • Vandermeer, M.L.1    Thomas, A.R.2    Kamimoto, L.3
  • 65
    • 84891810978 scopus 로고    scopus 로고
    • How will physicians respond to the next influenza pandemic?
    • Fedson DS How will physicians respond to the next influenza pandemic?. Clin Infect Dis 2014, 58:233-237.
    • (2014) Clin Infect Dis , vol.58 , pp. 233-237
    • Fedson, D.S.1
  • 66
    • 84893835937 scopus 로고    scopus 로고
    • DAS181 treatment of hematopoietic stem cell transplant patients with parainfluenza virus lung disease requiring mechanical ventilation
    • Chalkias S, Mackenzie MR, Gay C, et al. DAS181 treatment of hematopoietic stem cell transplant patients with parainfluenza virus lung disease requiring mechanical ventilation. Transpl Infect Dis 2014, 16:141-144.
    • (2014) Transpl Infect Dis , vol.16 , pp. 141-144
    • Chalkias, S.1    Mackenzie, M.R.2    Gay, C.3
  • 67
    • 84870226652 scopus 로고    scopus 로고
    • A phase II study of DAS181, a novel host directed antiviral for the treatment of influenza infection
    • Moss RB, Hansen C, Sanders RL, Hawley S, Li T, Steigbigel RT A phase II study of DAS181, a novel host directed antiviral for the treatment of influenza infection. J Infect Dis 2012, 206:1844-1851.
    • (2012) J Infect Dis , vol.206 , pp. 1844-1851
    • Moss, R.B.1    Hansen, C.2    Sanders, R.L.3    Hawley, S.4    Li, T.5    Steigbigel, R.T.6
  • 68
    • 84936951142 scopus 로고    scopus 로고
    • Treating the host response to Ebola virus disease with generic statins and angiotensin receptor blockers
    • Fedson DS, Jacobson JR, Rordam OM, Opal SM Treating the host response to Ebola virus disease with generic statins and angiotensin receptor blockers. MBio 2015, 6:e00716.
    • (2015) MBio , vol.6 , pp. e00716
    • Fedson, D.S.1    Jacobson, J.R.2    Rordam, O.M.3    Opal, S.M.4
  • 69
    • 84934300285 scopus 로고    scopus 로고
    • Treating Ebola patients: a 'bottom up' approach using generic statins and angiotensin receptor blockers
    • Fedson DS, Rordam OM Treating Ebola patients: a 'bottom up' approach using generic statins and angiotensin receptor blockers. Int J Infect Dis 2015, 36:80-84.
    • (2015) Int J Infect Dis , vol.36 , pp. 80-84
    • Fedson, D.S.1    Rordam, O.M.2
  • 70
    • 85045802748 scopus 로고    scopus 로고
    • Categorization and prioritization of drugs for consideration for testing or use in patients infected with Ebola WHO, (accessed Feb 10, 2016). http://www.who.int/medicines/ebola-treatment/2015-0218_tables_of_ebola_drugs_updated.pdf.
  • 71
    • 84889562469 scopus 로고    scopus 로고
    • Sustained protection against Ebola virus infection following treatment of infected nonhuman primates with ZMAb
    • Qiu X, Audet J, Wong G, et al. Sustained protection against Ebola virus infection following treatment of infected nonhuman primates with ZMAb. Sci Rep 2013, 3:3365.
    • (2013) Sci Rep , vol.3 , pp. 3365
    • Qiu, X.1    Audet, J.2    Wong, G.3
  • 72
    • 10744222633 scopus 로고    scopus 로고
    • Treatment of Ebola virus infection with a recombinant inhibitor of factor VIIa/tissue factor: a study in rhesus monkeys
    • Geisbert TW, Hensley LE, Jahrling PB, et al. Treatment of Ebola virus infection with a recombinant inhibitor of factor VIIa/tissue factor: a study in rhesus monkeys. Lancet 2003, 362:1953-1958.
    • (2003) Lancet , vol.362 , pp. 1953-1958
    • Geisbert, T.W.1    Hensley, L.E.2    Jahrling, P.B.3
  • 73
    • 67349187399 scopus 로고    scopus 로고
    • Cholesterol biosynthesis modulation regulates dengue viral replication
    • Rothwell C, Lebreton A, Young Ng C, et al. Cholesterol biosynthesis modulation regulates dengue viral replication. Virology 2009, 389:8-19.
    • (2009) Virology , vol.389 , pp. 8-19
    • Rothwell, C.1    Lebreton, A.2    Young Ng, C.3
  • 74
    • 84880385563 scopus 로고    scopus 로고
    • The small molecules AZD0530 and dasatinib inhibit dengue virus RNA replication via Fyn kinase
    • de Wispelaere M, LaCroix AJ, Yang PL The small molecules AZD0530 and dasatinib inhibit dengue virus RNA replication via Fyn kinase. J Virol 2013, 87:7367-7381.
    • (2013) J Virol , vol.87 , pp. 7367-7381
    • de Wispelaere, M.1    LaCroix, A.J.2    Yang, P.L.3
  • 75
    • 84893952668 scopus 로고    scopus 로고
    • Targeting host factors to treat West Nile and dengue viral infections
    • Krishnan MN, Garcia-Blanco MA Targeting host factors to treat West Nile and dengue viral infections. Viruses 2014, 6:683-708.
    • (2014) Viruses , vol.6 , pp. 683-708
    • Krishnan, M.N.1    Garcia-Blanco, M.A.2
  • 76
    • 84959851955 scopus 로고    scopus 로고
    • Middle East respiratory syndrome coronavirus: another zoonotic betacoronavirus causing SARS-like disease
    • Chan JF, Lau SK, To KK, Cheng VC, Woo PC, Yuen KY Middle East respiratory syndrome coronavirus: another zoonotic betacoronavirus causing SARS-like disease. Clin Microbiol Rev 2015, 28:465-522.
    • (2015) Clin Microbiol Rev , vol.28 , pp. 465-522
    • Chan, J.F.1    Lau, S.K.2    To, K.K.3    Cheng, V.C.4    Woo, P.C.5    Yuen, K.Y.6
  • 78
    • 84957818744 scopus 로고    scopus 로고
    • Zumla A, Chan JF, Azhar EI, Hui DS, Yuen KY Coronaviruses-drug discovery and therapeutic options. Nat Rev Drug Discov 2016, published online Feb 12. 10.1038/nrd.2015.37.
  • 79
    • 84922145857 scopus 로고    scopus 로고
    • Red cells from ferrochelatase-deficient erythropoietic protoporphyria patients are resistant to growth of malarial parasites
    • Smith CM, Jerkovic A, Puy H, et al. Red cells from ferrochelatase-deficient erythropoietic protoporphyria patients are resistant to growth of malarial parasites. Blood 2015, 125:534-541.
    • (2015) Blood , vol.125 , pp. 534-541
    • Smith, C.M.1    Jerkovic, A.2    Puy, H.3
  • 80
    • 84928802858 scopus 로고    scopus 로고
    • Peptide IDR-1018: modulating the immune system and targeting bacterial biofilms to treat antibiotic-resistant bacterial infections
    • Mansour SC, de la Fuente-Nunez C, Hancock RE Peptide IDR-1018: modulating the immune system and targeting bacterial biofilms to treat antibiotic-resistant bacterial infections. J Pept Sci 2015, 21:323-329.
    • (2015) J Pept Sci , vol.21 , pp. 323-329
    • Mansour, S.C.1    de la Fuente-Nunez, C.2    Hancock, R.E.3
  • 81
    • 84861477057 scopus 로고    scopus 로고
    • Effective adjunctive therapy by an innate defense regulatory peptide in a preclinical model of severe malaria
    • 135ra64
    • Achtman AH, Pilat S, Law CW, et al. Effective adjunctive therapy by an innate defense regulatory peptide in a preclinical model of severe malaria. Sci Transl Med 2012, 4:135ra64.
    • (2012) Sci Transl Med , vol.4
    • Achtman, A.H.1    Pilat, S.2    Law, C.W.3
  • 82
    • 84888358662 scopus 로고    scopus 로고
    • Delivery of host cell-directed therapeutics for intracellular pathogen clearance
    • Collier MA, Gallovic MD, Peine KJ, et al. Delivery of host cell-directed therapeutics for intracellular pathogen clearance. Expert Rev Anti Infect Ther 2013, 11:1225-1235.
    • (2013) Expert Rev Anti Infect Ther , vol.11 , pp. 1225-1235
    • Collier, M.A.1    Gallovic, M.D.2    Peine, K.J.3
  • 83
    • 84929463379 scopus 로고    scopus 로고
    • Chondroitin nanocapsules enhanced doxorubicin induced apoptosis against leishmaniasis via Th1 immune response
    • Chaurasia M, Pawar VK, Jaiswal AK, Dube A, Paliwal SK, Chourasia MK Chondroitin nanocapsules enhanced doxorubicin induced apoptosis against leishmaniasis via Th1 immune response. Int J Biol Macromol 2015, 79:27-36.
    • (2015) Int J Biol Macromol , vol.79 , pp. 27-36
    • Chaurasia, M.1    Pawar, V.K.2    Jaiswal, A.K.3    Dube, A.4    Paliwal, S.K.5    Chourasia, M.K.6
  • 84
    • 77950849328 scopus 로고    scopus 로고
    • Current diagnosis and treatment of cutaneous and mucocutaneous leishmaniasis
    • Goto H, Lindoso JA Current diagnosis and treatment of cutaneous and mucocutaneous leishmaniasis. Expert Rev Anti Infect Ther 2010, 8:419-433.
    • (2010) Expert Rev Anti Infect Ther , vol.8 , pp. 419-433
    • Goto, H.1    Lindoso, J.A.2
  • 85
    • 79960408016 scopus 로고    scopus 로고
    • Human host determinants influencing the outcome of Trypanosoma brucei gambiense infections
    • Bucheton B, MacLeod A, Jamonneau V Human host determinants influencing the outcome of Trypanosoma brucei gambiense infections. Parasite Immunol 2011, 33:438-447.
    • (2011) Parasite Immunol , vol.33 , pp. 438-447
    • Bucheton, B.1    MacLeod, A.2    Jamonneau, V.3
  • 86
    • 84908132425 scopus 로고    scopus 로고
    • Plasticity of mesenchymal stem cells in immunomodulation: pathological and therapeutic implications
    • Wang Y, Chen X, Cao W, Shi Y Plasticity of mesenchymal stem cells in immunomodulation: pathological and therapeutic implications. Nat Immunol 2014, 15:1009-1016.
    • (2014) Nat Immunol , vol.15 , pp. 1009-1016
    • Wang, Y.1    Chen, X.2    Cao, W.3    Shi, Y.4
  • 87
    • 84881666717 scopus 로고    scopus 로고
    • Novel therapeutic and prevention approaches for schistosomiasis: review
    • El Ridi RA, Tallima HA Novel therapeutic and prevention approaches for schistosomiasis: review. J Adv Res 2013, 4:467-478.
    • (2013) J Adv Res , vol.4 , pp. 467-478
    • El Ridi, R.A.1    Tallima, H.A.2
  • 88
    • 84876704528 scopus 로고    scopus 로고
    • Vaccine-induced protection against murine schistosomiasis mansoni with larval excretory-secretory antigens and papain or type-2 cytokines
    • El Ridi R, Tallima H Vaccine-induced protection against murine schistosomiasis mansoni with larval excretory-secretory antigens and papain or type-2 cytokines. J Parasitol 2013, 99:194-202.
    • (2013) J Parasitol , vol.99 , pp. 194-202
    • El Ridi, R.1    Tallima, H.2
  • 89
    • 85045802990 scopus 로고    scopus 로고
    • Global tuberculosis report 2015 2015, WHO, World Health Organization, Geneva, (accessed Feb 10, 2016). http://www.who.int/tb/publications/global_report/en/.
  • 91
    • 84925365327 scopus 로고    scopus 로고
    • Inflammation and tuberculosis: host-directed therapies
    • Zumla A, Rao M, Parida SK, et al. Inflammation and tuberculosis: host-directed therapies. J Intern Med 2015, 277:373-387.
    • (2015) J Intern Med , vol.277 , pp. 373-387
    • Zumla, A.1    Rao, M.2    Parida, S.K.3
  • 92
    • 84911883683 scopus 로고    scopus 로고
    • Metformin as adjunct antituberculosis therapy
    • 263ra159
    • Singhal A, Jie L, Kumar P, et al. Metformin as adjunct antituberculosis therapy. Sci Transl Med 2014, 6:263ra159.
    • (2014) Sci Transl Med , vol.6
    • Singhal, A.1    Jie, L.2    Kumar, P.3
  • 93
    • 67650096912 scopus 로고    scopus 로고
    • Enhancing CD8 T-cell memory by modulating fatty acid metabolism
    • Pearce EL, Walsh MC, Cejas PJ, et al. Enhancing CD8 T-cell memory by modulating fatty acid metabolism. Nature 2009, 460:103-107.
    • (2009) Nature , vol.460 , pp. 103-107
    • Pearce, E.L.1    Walsh, M.C.2    Cejas, P.J.3
  • 94
    • 77954177589 scopus 로고    scopus 로고
    • A high-throughput respirometric assay for mitochondrial biogenesis and toxicity
    • Beeson CC, Beeson GC, Schnellmann RG A high-throughput respirometric assay for mitochondrial biogenesis and toxicity. Anal Biochem 2010, 404:75-81.
    • (2010) Anal Biochem , vol.404 , pp. 75-81
    • Beeson, C.C.1    Beeson, G.C.2    Schnellmann, R.G.3
  • 95
    • 84902270555 scopus 로고    scopus 로고
    • Pharmacological Inhibition of poly(ADP-ribose) polymerases improves fitness and mitochondrial function in skeletal muscle
    • Pirinen E, Cantó C, Jo YS, et al. Pharmacological Inhibition of poly(ADP-ribose) polymerases improves fitness and mitochondrial function in skeletal muscle. Cell Metab 2014, 19:1034-1041.
    • (2014) Cell Metab , vol.19 , pp. 1034-1041
    • Pirinen, E.1    Cantó, C.2    Jo, Y.S.3
  • 96
    • 84856183120 scopus 로고    scopus 로고
    • Mitochondrial respiratory capacity is a critical regulator of CD8+ T cell memory development
    • van der Windt GJ, Everts B, Chang CH, et al. Mitochondrial respiratory capacity is a critical regulator of CD8+ T cell memory development. Immunity 2012, 36:68-78.
    • (2012) Immunity , vol.36 , pp. 68-78
    • van der Windt, G.J.1    Everts, B.2    Chang, C.H.3
  • 97
    • 84907412761 scopus 로고    scopus 로고
    • IL-32 is a molecular marker of a host defense network in human tuberculosis
    • 250ra114
    • Montoya D, Inkeles MS, Liu PT, et al. IL-32 is a molecular marker of a host defense network in human tuberculosis. Sci Transl Med 2014, 6:250ra114.
    • (2014) Sci Transl Med , vol.6
    • Montoya, D.1    Inkeles, M.S.2    Liu, P.T.3
  • 98
    • 84880055561 scopus 로고    scopus 로고
    • An enzyme that inactivates the inflammatory mediator leukotriene b4 restricts mycobacterial infection
    • Tobin DM, Roca FJ, Ray JP, Ko DC, Ramakrishnan L An enzyme that inactivates the inflammatory mediator leukotriene b4 restricts mycobacterial infection. PLoS One 2013, 8:e67828.
    • (2013) PLoS One , vol.8 , pp. e67828
    • Tobin, D.M.1    Roca, F.J.2    Ray, J.P.3    Ko, D.C.4    Ramakrishnan, L.5
  • 99
    • 84903750131 scopus 로고    scopus 로고
    • Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk
    • Mayer-Barber KD, Andrade BB, Oland SD, et al. Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk. Nature 2014, 511:99-103.
    • (2014) Nature , vol.511 , pp. 99-103
    • Mayer-Barber, K.D.1    Andrade, B.B.2    Oland, S.D.3
  • 100
    • 84879405292 scopus 로고    scopus 로고
    • Ibuprofen therapy resulted in significantly decreased tissue bacillary loads and increased survival in a new murine experimental model of active tuberculosis
    • Vilaplana C, Marzo E, Tapia G, Diaz J, Garcia V, Cardona PJ Ibuprofen therapy resulted in significantly decreased tissue bacillary loads and increased survival in a new murine experimental model of active tuberculosis. J Infect Dis 2013, 208:199-202.
    • (2013) J Infect Dis , vol.208 , pp. 199-202
    • Vilaplana, C.1    Marzo, E.2    Tapia, G.3    Diaz, J.4    Garcia, V.5    Cardona, P.J.6
  • 101
    • 84879392633 scopus 로고    scopus 로고
    • Nonsteroidal antiinflammatory drugs for adjunctive tuberculosis treatment
    • Ivanyi J, Zumla A Nonsteroidal antiinflammatory drugs for adjunctive tuberculosis treatment. J Infect Dis 2013, 208:185-188.
    • (2013) J Infect Dis , vol.208 , pp. 185-188
    • Ivanyi, J.1    Zumla, A.2
  • 102
    • 84874229114 scopus 로고    scopus 로고
    • Corticosteroids for prevention of mortality in people with tuberculosis: a systematic review and meta-analysis
    • Critchley JA, Young F, Orton L, Garner P Corticosteroids for prevention of mortality in people with tuberculosis: a systematic review and meta-analysis. Lancet Infect Dis 2013, 13:223-237.
    • (2013) Lancet Infect Dis , vol.13 , pp. 223-237
    • Critchley, J.A.1    Young, F.2    Orton, L.3    Garner, P.4
  • 103
    • 84863337769 scopus 로고    scopus 로고
    • Stimulation of HIV-1-specific cytolytic T lymphocytes facilitates elimination of latent viral reservoir after virus reactivation
    • Shan L, Deng K, Shroff NS, et al. Stimulation of HIV-1-specific cytolytic T lymphocytes facilitates elimination of latent viral reservoir after virus reactivation. Immunity 2012, 36:491-501.
    • (2012) Immunity , vol.36 , pp. 491-501
    • Shan, L.1    Deng, K.2    Shroff, N.S.3
  • 104
    • 84938800599 scopus 로고    scopus 로고
    • Phenylbutyrate is bacteriostatic against Mycobacterium tuberculosis and regulates the macrophage response to infection, synergistically with 25-hydroxy-vitamin D3
    • Coussens AK, Wilkinson RJ, Martineau AR Phenylbutyrate is bacteriostatic against Mycobacterium tuberculosis and regulates the macrophage response to infection, synergistically with 25-hydroxy-vitamin D3. PLoS Pathog 2015, 11:e1005007.
    • (2015) PLoS Pathog , vol.11
    • Coussens, A.K.1    Wilkinson, R.J.2    Martineau, A.R.3
  • 105
    • 84912051287 scopus 로고    scopus 로고
    • Phenylbutyrate induces cathelicidin expression via the vitamin D receptor: linkage to inflammatory and growth factor cytokines pathways
    • Kulkarni NN, Yi Z, Huehnken C, Agerberth B, Gudmundsson GH Phenylbutyrate induces cathelicidin expression via the vitamin D receptor: linkage to inflammatory and growth factor cytokines pathways. Mol Immunol 2015, 63:530-539.
    • (2015) Mol Immunol , vol.63 , pp. 530-539
    • Kulkarni, N.N.1    Yi, Z.2    Huehnken, C.3    Agerberth, B.4    Gudmundsson, G.H.5
  • 106
    • 0026723149 scopus 로고
    • Mechanisms of action of, and modes of resistance to, alkylating agents used in the treatment of haematological malignancies
    • Hall AG, Tilby MJ Mechanisms of action of, and modes of resistance to, alkylating agents used in the treatment of haematological malignancies. Blood Rev 1992, 6:163-173.
    • (1992) Blood Rev , vol.6 , pp. 163-173
    • Hall, A.G.1    Tilby, M.J.2
  • 107
    • 84864662070 scopus 로고    scopus 로고
    • Multipeptide immune response to cancer vaccine IMA901 after single-dose cyclophosphamide associates with longer patient survival
    • Walter S, Weinschenk T, Stenzl A, et al. Multipeptide immune response to cancer vaccine IMA901 after single-dose cyclophosphamide associates with longer patient survival. Nat Med 2012, 18:1254-1261.
    • (2012) Nat Med , vol.18 , pp. 1254-1261
    • Walter, S.1    Weinschenk, T.2    Stenzl, A.3
  • 108
    • 33644848507 scopus 로고    scopus 로고
    • Cytotoxic therapy for severe avian influenza A (H5N1) infection
    • Henter JI, Chow CB, Leung CW, Lau YL Cytotoxic therapy for severe avian influenza A (H5N1) infection. Lancet 2006, 367:870-873.
    • (2006) Lancet , vol.367 , pp. 870-873
    • Henter, J.I.1    Chow, C.B.2    Leung, C.W.3    Lau, Y.L.4
  • 110
    • 84920107783 scopus 로고    scopus 로고
    • Verapamil increases the bactericidal activity of bedaquiline against Mycobacterium tuberculosis in a mouse model
    • Gupta S, Tyagi S, Bishai WR Verapamil increases the bactericidal activity of bedaquiline against Mycobacterium tuberculosis in a mouse model. Antimicrob Agents Chemother 2015, 59:673-676.
    • (2015) Antimicrob Agents Chemother , vol.59 , pp. 673-676
    • Gupta, S.1    Tyagi, S.2    Bishai, W.R.3
  • 111
    • 84922062811 scopus 로고    scopus 로고
    • Functional drug screening reveals anticonvulsants as enhancers of mTOR-independent autophagic killing of Mycobacterium tuberculosis through inositol depletion
    • Schiebler M, Brown K, Hegyi K, et al. Functional drug screening reveals anticonvulsants as enhancers of mTOR-independent autophagic killing of Mycobacterium tuberculosis through inositol depletion. EMBO Mol Med 2015, 7:127-139.
    • (2015) EMBO Mol Med , vol.7 , pp. 127-139
    • Schiebler, M.1    Brown, K.2    Hegyi, K.3
  • 112
    • 84894226758 scopus 로고    scopus 로고
    • Statin therapy reduces the Mycobacterium tuberculosis burden in human macrophages and in mice by enhancing autophagy and phagosome maturation
    • Parihar SP, Guler R, Khutlang R, et al. Statin therapy reduces the Mycobacterium tuberculosis burden in human macrophages and in mice by enhancing autophagy and phagosome maturation. J Infect Dis 2014, 209:754-763.
    • (2014) J Infect Dis , vol.209 , pp. 754-763
    • Parihar, S.P.1    Guler, R.2    Khutlang, R.3
  • 113
    • 0842283056 scopus 로고    scopus 로고
    • Salmonella enterica serovar Typhimurium requires nonsterol precursors of the cholesterol biosynthetic pathway for intracellular proliferation
    • Catron DM, Lange Y, Borensztajn J, Sylvester MD, Jones BD, Haldar K Salmonella enterica serovar Typhimurium requires nonsterol precursors of the cholesterol biosynthetic pathway for intracellular proliferation. Infect Immun 2004, 72:1036-1042.
    • (2004) Infect Immun , vol.72 , pp. 1036-1042
    • Catron, D.M.1    Lange, Y.2    Borensztajn, J.3    Sylvester, M.D.4    Jones, B.D.5    Haldar, K.6
  • 114
    • 84926466672 scopus 로고    scopus 로고
    • Low doses of imatinib induce myelopoiesis and enhance host anti-microbial immunity
    • Napier RJ, Norris BA, Swimm A, et al. Low doses of imatinib induce myelopoiesis and enhance host anti-microbial immunity. PLoS Pathog 2015, 11:e1004770.
    • (2015) PLoS Pathog , vol.11
    • Napier, R.J.1    Norris, B.A.2    Swimm, A.3
  • 115
    • 84928209680 scopus 로고    scopus 로고
    • Adjunctive vitamin D for treatment of active tuberculosis in India: a randomised, double-blind, placebo-controlled trial
    • Daley P, Jagannathan V, John KR, et al. Adjunctive vitamin D for treatment of active tuberculosis in India: a randomised, double-blind, placebo-controlled trial. Lancet Infect Dis 2015, 15:528-534.
    • (2015) Lancet Infect Dis , vol.15 , pp. 528-534
    • Daley, P.1    Jagannathan, V.2    John, K.R.3
  • 116
    • 84919897426 scopus 로고    scopus 로고
    • Pulmonary tuberculosis patients with a vitamin D deficiency demonstrate low local expression of the antimicrobial peptide LL-37 but enhanced FoxP3+ regulatory T cells and IgG-secreting cells
    • Rahman S, Rehn A, Rahman J, Andersson J, Svensson M, Brighenti S Pulmonary tuberculosis patients with a vitamin D deficiency demonstrate low local expression of the antimicrobial peptide LL-37 but enhanced FoxP3+ regulatory T cells and IgG-secreting cells. Clin Immunol 2015, 156:85-97.
    • (2015) Clin Immunol , vol.156 , pp. 85-97
    • Rahman, S.1    Rehn, A.2    Rahman, J.3    Andersson, J.4    Svensson, M.5    Brighenti, S.6
  • 117
    • 84897959389 scopus 로고    scopus 로고
    • Progress in tuberculosis vaccine development and host-directed therapies-a state of the art review
    • Kaufmann SH, Lange C, Rao M, et al. Progress in tuberculosis vaccine development and host-directed therapies-a state of the art review. Lancet Respir Med 2014, 2:301-320.
    • (2014) Lancet Respir Med , vol.2 , pp. 301-320
    • Kaufmann, S.H.1    Lange, C.2    Rao, M.3
  • 118
    • 84937852364 scopus 로고    scopus 로고
    • The CD28-B7 family in anti-tumor immunity: emerging concepts in cancer immunotherapy
    • Leung J, Suh WK The CD28-B7 family in anti-tumor immunity: emerging concepts in cancer immunotherapy. Immune Netw 2014, 14:265-276.
    • (2014) Immune Netw , vol.14 , pp. 265-276
    • Leung, J.1    Suh, W.K.2
  • 119
    • 84858766182 scopus 로고    scopus 로고
    • The blockade of immune checkpoints in cancer immunotherapy
    • Pardoll DM The blockade of immune checkpoints in cancer immunotherapy. Nat Rev Cancer 2012, 12:252-264.
    • (2012) Nat Rev Cancer , vol.12 , pp. 252-264
    • Pardoll, D.M.1
  • 120
    • 84880944556 scopus 로고    scopus 로고
    • Inhibiting the programmed death 1 pathway rescues Mycobacterium tuberculosis-specific interferon γ-producing T cells from apoptosis in patients with pulmonary tuberculosis
    • Singh A, Mohan A, Dey AB, Mitra DK Inhibiting the programmed death 1 pathway rescues Mycobacterium tuberculosis-specific interferon γ-producing T cells from apoptosis in patients with pulmonary tuberculosis. J Infect Dis 2013, 208:603-615.
    • (2013) J Infect Dis , vol.208 , pp. 603-615
    • Singh, A.1    Mohan, A.2    Dey, A.B.3    Mitra, D.K.4
  • 121
    • 47949107182 scopus 로고    scopus 로고
    • Programmed death (PD)-1:PD-ligand 1/PD-ligand 2 pathway inhibits T cell effector functions during human tuberculosis
    • Jurado JO, Alvarez IB, Pasquinelli V, et al. Programmed death (PD)-1:PD-ligand 1/PD-ligand 2 pathway inhibits T cell effector functions during human tuberculosis. J Immunol 2008, 181:116-125.
    • (2008) J Immunol , vol.181 , pp. 116-125
    • Jurado, J.O.1    Alvarez, I.B.2    Pasquinelli, V.3
  • 122
    • 84945120679 scopus 로고    scopus 로고
    • PD-1, PD-L1 and PD-L2 gene expression on T-cells and natural killer cells declines in conjunction with a reduction in PD-1 protein during the intensive phase of tuberculosis treatment
    • Hassan SS, Akram M, King EC, Dockrell HM, Cliff JM PD-1, PD-L1 and PD-L2 gene expression on T-cells and natural killer cells declines in conjunction with a reduction in PD-1 protein during the intensive phase of tuberculosis treatment. PLoS One 2015, 10:e0137646.
    • (2015) PLoS One , vol.10
    • Hassan, S.S.1    Akram, M.2    King, E.C.3    Dockrell, H.M.4    Cliff, J.M.5
  • 123
    • 80155127321 scopus 로고    scopus 로고
    • Prospects for TIM3-targeted antitumor immunotherapy
    • Ngiow SF, Teng MW, Smyth MJ Prospects for TIM3-targeted antitumor immunotherapy. Cancer Res 2011, 71:6567-6571.
    • (2011) Cancer Res , vol.71 , pp. 6567-6571
    • Ngiow, S.F.1    Teng, M.W.2    Smyth, M.J.3
  • 124
    • 84871105902 scopus 로고    scopus 로고
    • The Tim3-galectin 9 pathway induces antibacterial activity in human macrophages infected with Mycobacterium tuberculosis
    • Sada-Ovalle I, Chávez-Galán L, Torre-Bouscoulet L, et al. The Tim3-galectin 9 pathway induces antibacterial activity in human macrophages infected with Mycobacterium tuberculosis. J Immunol 2012, 189:5896-5902.
    • (2012) J Immunol , vol.189 , pp. 5896-5902
    • Sada-Ovalle, I.1    Chávez-Galán, L.2    Torre-Bouscoulet, L.3
  • 126
    • 84925545111 scopus 로고    scopus 로고
    • Clinical blockade of PD1 and LAG3-potential mechanisms of action
    • Nguyen LT, Ohashi PS Clinical blockade of PD1 and LAG3-potential mechanisms of action. Nat Rev Immunol 2015, 15:45-56.
    • (2015) Nat Rev Immunol , vol.15 , pp. 45-56
    • Nguyen, L.T.1    Ohashi, P.S.2
  • 127
    • 65549150749 scopus 로고    scopus 로고
    • Adalimumab treatment of life-threatening tuberculosis
    • Wallis RS, van Vuuren C, Potgieter S Adalimumab treatment of life-threatening tuberculosis. Clin Infect Dis 2009, 48:1429-1432.
    • (2009) Clin Infect Dis , vol.48 , pp. 1429-1432
    • Wallis, R.S.1    van Vuuren, C.2    Potgieter, S.3
  • 129
    • 84925365657 scopus 로고    scopus 로고
    • Immunological profiling of tuberculosis-associated immune reconstitution inflammatory syndrome and non-immune reconstitution inflammatory syndrome death in HIV-infected adults with pulmonary tuberculosis starting antiretroviral therapy: a prospective observational cohort study
    • Ravimohan S, Tamuhla N, Steenhoff AP, et al. Immunological profiling of tuberculosis-associated immune reconstitution inflammatory syndrome and non-immune reconstitution inflammatory syndrome death in HIV-infected adults with pulmonary tuberculosis starting antiretroviral therapy: a prospective observational cohort study. Lancet Infect Dis 2015, 15:429-438.
    • (2015) Lancet Infect Dis , vol.15 , pp. 429-438
    • Ravimohan, S.1    Tamuhla, N.2    Steenhoff, A.P.3
  • 130
    • 84922593368 scopus 로고    scopus 로고
    • Anti-vascular endothelial growth factor treatment normalizes tuberculosis granuloma vasculature and improves small molecule delivery
    • Datta M, Via LE, Kamoun WS, et al. Anti-vascular endothelial growth factor treatment normalizes tuberculosis granuloma vasculature and improves small molecule delivery. Proc Natl Acad Sci USA 2015, 112:1827-1832.
    • (2015) Proc Natl Acad Sci USA , vol.112 , pp. 1827-1832
    • Datta, M.1    Via, L.E.2    Kamoun, W.S.3
  • 131
    • 84925537336 scopus 로고    scopus 로고
    • Interception of host angiogenic signalling limits mycobacterial growth
    • Oehlers SH, Cronan MR, Scott NR, et al. Interception of host angiogenic signalling limits mycobacterial growth. Nature 2015, 517:612-615.
    • (2015) Nature , vol.517 , pp. 612-615
    • Oehlers, S.H.1    Cronan, M.R.2    Scott, N.R.3
  • 132
    • 84895074569 scopus 로고    scopus 로고
    • Autologous mesenchymal stromal cell infusion as adjunct treatment in patients with multidrug and extensively drug-resistant tuberculosis: an open-label phase 1 safety trial
    • Skrahin A, Ahmed RK, Ferrara G, et al. Autologous mesenchymal stromal cell infusion as adjunct treatment in patients with multidrug and extensively drug-resistant tuberculosis: an open-label phase 1 safety trial. Lancet Respir Med 2014, 2:108-122.
    • (2014) Lancet Respir Med , vol.2 , pp. 108-122
    • Skrahin, A.1    Ahmed, R.K.2    Ferrara, G.3
  • 133
    • 84938418174 scopus 로고    scopus 로고
    • Towards host-directed therapies for tuberculosis
    • the Host-Directed Therapies Network
    • Zumla A, Maeurer M, Chakaya J, et al. Towards host-directed therapies for tuberculosis. Nat Rev Drug Discov 2015, 14:511-512. the Host-Directed Therapies Network.
    • (2015) Nat Rev Drug Discov , vol.14 , pp. 511-512
    • Zumla, A.1    Maeurer, M.2    Chakaya, J.3
  • 134
    • 69949111769 scopus 로고    scopus 로고
    • Burden of disease caused by Streptococcus pneumoniae in children younger than 5 years: global estimates
    • the Hib and Pneumococcal Global Burden of Disease Study Team
    • O'Brien KL, Wolfson LJ, Watt JP, et al. Burden of disease caused by Streptococcus pneumoniae in children younger than 5 years: global estimates. Lancet 2009, 374:893-902. the Hib and Pneumococcal Global Burden of Disease Study Team.
    • (2009) Lancet , vol.374 , pp. 893-902
    • O'Brien, K.L.1    Wolfson, L.J.2    Watt, J.P.3
  • 135
    • 0034030433 scopus 로고    scopus 로고
    • Ten-year review of invasive pneumococcal diseases in children and adults from Uruguay: clinical spectrum, serotypes, and antimicrobial resistance
    • Hortal M, Camou T, Palacio R, Dibarboure H, Garcia A Ten-year review of invasive pneumococcal diseases in children and adults from Uruguay: clinical spectrum, serotypes, and antimicrobial resistance. Int J Infect Dis 2000, 4:91-95.
    • (2000) Int J Infect Dis , vol.4 , pp. 91-95
    • Hortal, M.1    Camou, T.2    Palacio, R.3    Dibarboure, H.4    Garcia, A.5
  • 136
    • 84939541833 scopus 로고    scopus 로고
    • Humoral immune responses to Streptococcus pneumoniae in the setting of HIV-1 infection
    • Zhang L, Li Z, Wan Z, Kilby A, Kilby JM, Jiang W Humoral immune responses to Streptococcus pneumoniae in the setting of HIV-1 infection. Vaccine 2015, 33:4430-4436.
    • (2015) Vaccine , vol.33 , pp. 4430-4436
    • Zhang, L.1    Li, Z.2    Wan, Z.3    Kilby, A.4    Kilby, J.M.5    Jiang, W.6
  • 137
    • 84907045288 scopus 로고    scopus 로고
    • Immunomodulatory adjuvant therapy in severe community-acquired pneumonia
    • Morton B, Pennington SH, Gordon SB Immunomodulatory adjuvant therapy in severe community-acquired pneumonia. Expert Rev Respir Med 2014, 8:587-596.
    • (2014) Expert Rev Respir Med , vol.8 , pp. 587-596
    • Morton, B.1    Pennington, S.H.2    Gordon, S.B.3
  • 139
    • 79551589611 scopus 로고    scopus 로고
    • Nonsteroidal antiinflammatory drugs may affect the presentation and course of community-acquired pneumonia
    • Voiriot G, Dury S, Parrot A, Mayaud C, Fartoukh M Nonsteroidal antiinflammatory drugs may affect the presentation and course of community-acquired pneumonia. Chest 2011, 139:387-394.
    • (2011) Chest , vol.139 , pp. 387-394
    • Voiriot, G.1    Dury, S.2    Parrot, A.3    Mayaud, C.4    Fartoukh, M.5
  • 140
    • 79953764920 scopus 로고    scopus 로고
    • Glyburide is anti-inflammatory and associated with reduced mortality in melioidosis
    • Koh GC, Maude RR, Schreiber MF, et al. Glyburide is anti-inflammatory and associated with reduced mortality in melioidosis. Clin Infect Dis 2011, 52:717-725.
    • (2011) Clin Infect Dis , vol.52 , pp. 717-725
    • Koh, G.C.1    Maude, R.R.2    Schreiber, M.F.3
  • 142
    • 33847201150 scopus 로고    scopus 로고
    • An African origin for the intimate association between humans and Helicobacter pylori
    • Linz B, Balloux F, Moodley Y, et al. An African origin for the intimate association between humans and Helicobacter pylori. Nature 2007, 445:915-918.
    • (2007) Nature , vol.445 , pp. 915-918
    • Linz, B.1    Balloux, F.2    Moodley, Y.3
  • 143
  • 144
    • 17644388063 scopus 로고    scopus 로고
    • Annulling a dangerous liaison: vaccination strategies against AIDS and tuberculosis
    • Kaufmann SH, McMichael AJ Annulling a dangerous liaison: vaccination strategies against AIDS and tuberculosis. Nat Med 2005, 11(suppl):S33-S44.
    • (2005) Nat Med , vol.11 , pp. S33-S44
    • Kaufmann, S.H.1    McMichael, A.J.2
  • 145
    • 0036237573 scopus 로고    scopus 로고
    • Prospects for immune reconstitution in HIV-1 infection
    • Imami N, Gotch F Prospects for immune reconstitution in HIV-1 infection. Clin Exp Immunol 2002, 127:402-411.
    • (2002) Clin Exp Immunol , vol.127 , pp. 402-411
    • Imami, N.1    Gotch, F.2
  • 146
    • 84959490878 scopus 로고    scopus 로고
    • Lai RP, Meintjes G, Wilkinson RJ HIV-1 tuberculosis-associated immune reconstitution inflammatory syndrome. Semin Immunopathol 2015, published online Sept 30. 10.1007/S00281-015-0532-2.
  • 147
    • 84896732012 scopus 로고    scopus 로고
    • LPS-binding protein and IL-6 mark paradoxical tuberculosis immune reconstitution inflammatory syndrome in HIV patients
    • the TB-IRIS Study Group
    • Goovaerts O, Jennes W, Massinga-Loembé M, et al. LPS-binding protein and IL-6 mark paradoxical tuberculosis immune reconstitution inflammatory syndrome in HIV patients. PLoS One 2013, 8:e81856. the TB-IRIS Study Group.
    • (2013) PLoS One , vol.8 , pp. e81856
    • Goovaerts, O.1    Jennes, W.2    Massinga-Loembé, M.3
  • 149
    • 33749009709 scopus 로고    scopus 로고
    • Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction
    • Trautmann L, Janbazian L, Chomont N, et al. Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction. Nat Med 2006, 12:1198-1202.
    • (2006) Nat Med , vol.12 , pp. 1198-1202
    • Trautmann, L.1    Janbazian, L.2    Chomont, N.3
  • 150
    • 79955418828 scopus 로고    scopus 로고
    • Harnessing the biology of IL-7 for therapeutic application
    • Mackall CL, Fry TJ, Gress RE Harnessing the biology of IL-7 for therapeutic application. Nat Rev Immunol 2011, 11:330-342.
    • (2011) Nat Rev Immunol , vol.11 , pp. 330-342
    • Mackall, C.L.1    Fry, T.J.2    Gress, R.E.3
  • 151
    • 41649104652 scopus 로고    scopus 로고
    • Interleukin-21 regulates expression of key Epstein-Barr virus oncoproteins, EBNA2 and LMP1, in infected human B cells
    • Konforte D, Simard N, Paige CJ Interleukin-21 regulates expression of key Epstein-Barr virus oncoproteins, EBNA2 and LMP1, in infected human B cells. Virology 2008, 374:100-113.
    • (2008) Virology , vol.374 , pp. 100-113
    • Konforte, D.1    Simard, N.2    Paige, C.J.3
  • 152
    • 84947425793 scopus 로고    scopus 로고
    • Progress in the development of vaccines for hepatitis C virus infection
    • Ghasemi F, Rostami S, Meshkat Z Progress in the development of vaccines for hepatitis C virus infection. World J Gastroenterol 2015, 21:11984-12002.
    • (2015) World J Gastroenterol , vol.21 , pp. 11984-12002
    • Ghasemi, F.1    Rostami, S.2    Meshkat, Z.3
  • 153
    • 40149094779 scopus 로고    scopus 로고
    • High level of PD-1 expression on hepatitis C virus (HCV)-specific CD8+ and CD4+ T cells during acute HCV infection, irrespective of clinical outcome
    • Kasprowicz V, Schulze Zur Wiesch J, Kuntzen T, et al. High level of PD-1 expression on hepatitis C virus (HCV)-specific CD8+ and CD4+ T cells during acute HCV infection, irrespective of clinical outcome. J Virol 2008, 82:3154-3160.
    • (2008) J Virol , vol.82 , pp. 3154-3160
    • Kasprowicz, V.1    Schulze Zur Wiesch, J.2    Kuntzen, T.3
  • 154
    • 61449181280 scopus 로고    scopus 로고
    • Synergistic reversal of intrahepatic HCV-specific CD8 T cell exhaustion by combined PD-1/CTLA-4 blockade
    • Nakamoto N, Cho H, Shaked A, et al. Synergistic reversal of intrahepatic HCV-specific CD8 T cell exhaustion by combined PD-1/CTLA-4 blockade. PLoS Pathog 2009, 5:e1000313.
    • (2009) PLoS Pathog , vol.5
    • Nakamoto, N.1    Cho, H.2    Shaked, A.3
  • 155
    • 84939653819 scopus 로고    scopus 로고
    • Hepatitis C guidance: AASLD-IDSA recommendations for testing, managing, and treating adults infected with hepatitis C virus
    • the AASLD/IDSA HCV Guidance Panel
    • Panel AIHG Hepatitis C guidance: AASLD-IDSA recommendations for testing, managing, and treating adults infected with hepatitis C virus. Hepatology 2015, 62:932-954. the AASLD/IDSA HCV Guidance Panel.
    • (2015) Hepatology , vol.62 , pp. 932-954
    • Panel, A.I.H.G.1
  • 156
    • 84930730522 scopus 로고    scopus 로고
    • Current state of anti-PD-L1 and anti-PD-1 agents in cancer therapy
    • Swaika A, Hammond WA, Joseph RW Current state of anti-PD-L1 and anti-PD-1 agents in cancer therapy. Mol Immunol 2015, 67(2 pt A):4-17.
    • (2015) Mol Immunol , vol.67 , Issue.2 , pp. 4-17
    • Swaika, A.1    Hammond, W.A.2    Joseph, R.W.3
  • 157
    • 43949087893 scopus 로고    scopus 로고
    • Apolipoprotein B-dependent hepatitis C virus secretion is inhibited by the grapefruit flavonoid naringenin
    • Nahmias Y, Goldwasser J, Casali M, et al. Apolipoprotein B-dependent hepatitis C virus secretion is inhibited by the grapefruit flavonoid naringenin. Hepatology 2008, 47:1437-1445.
    • (2008) Hepatology , vol.47 , pp. 1437-1445
    • Nahmias, Y.1    Goldwasser, J.2    Casali, M.3
  • 158
    • 84869020353 scopus 로고    scopus 로고
    • Population-based study of statins, angiotensin II receptor blockers, and angiotensin-converting enzyme inhibitors on pneumonia-related outcomes
    • Mortensen EM, Nakashima B, Cornell J, et al. Population-based study of statins, angiotensin II receptor blockers, and angiotensin-converting enzyme inhibitors on pneumonia-related outcomes. Clin Infect Dis 2012, 55:1466-1473.
    • (2012) Clin Infect Dis , vol.55 , pp. 1466-1473
    • Mortensen, E.M.1    Nakashima, B.2    Cornell, J.3
  • 159
    • 85045802911 scopus 로고    scopus 로고
    • Ebola situation report WHO, (accessed Feb 26, 2016). http://apps.who.int/ebola/current-situation/ebola-situation-report-17-february-2016.
  • 160
    • 84944074721 scopus 로고    scopus 로고
    • The use of convalescent plasma to treat emerging infectious diseases: focus on Ebola virus disease
    • Winkler AM, Koepsell SA The use of convalescent plasma to treat emerging infectious diseases: focus on Ebola virus disease. Curr Opin Hematol 2015, 22:521-526.
    • (2015) Curr Opin Hematol , vol.22 , pp. 521-526
    • Winkler, A.M.1    Koepsell, S.A.2
  • 161
    • 84928951064 scopus 로고    scopus 로고
    • Insect-specific flaviviruses: a systematic review of their discovery, host range, mode of transmission, superinfection exclusion potential and genomic organization
    • Blitvich BJ, Firth AE Insect-specific flaviviruses: a systematic review of their discovery, host range, mode of transmission, superinfection exclusion potential and genomic organization. Viruses 2015, 7:1927-1959.
    • (2015) Viruses , vol.7 , pp. 1927-1959
    • Blitvich, B.J.1    Firth, A.E.2
  • 162
    • 84938090712 scopus 로고    scopus 로고
    • Why are people with dengue dying? A scoping review of determinants for dengue mortality
    • Carabali M, Hernandez LM, Arauz MJ, Villar LA, Ridde V Why are people with dengue dying? A scoping review of determinants for dengue mortality. BMC Infect Dis 2015, 15:301.
    • (2015) BMC Infect Dis , vol.15 , pp. 301
    • Carabali, M.1    Hernandez, L.M.2    Arauz, M.J.3    Villar, L.A.4    Ridde, V.5
  • 163
    • 85045802750 scopus 로고    scopus 로고
    • WHO World malaria report 2014 2014, World Health Organization, Geneva, (accessed Feb 10, 2016). http://www.who.int/malaria/publications/world_malaria_report_2014/en/.
  • 164
    • 84965083897 scopus 로고    scopus 로고
    • Antimalarial drug resistance: literature review and activities and findings of the ICEMR Network
    • Cui L, Mharakurwa S, Ndiaye D, Rathod PK, Rosenthal PJ Antimalarial drug resistance: literature review and activities and findings of the ICEMR Network. Am J Trop Med Hyg 2015, 93(suppl):57-68.
    • (2015) Am J Trop Med Hyg , vol.93 , pp. 57-68
    • Cui, L.1    Mharakurwa, S.2    Ndiaye, D.3    Rathod, P.K.4    Rosenthal, P.J.5
  • 165
    • 84990475398 scopus 로고
    • Iron chelation therapy for iron loaded patients
    • Jacobs A Iron chelation therapy for iron loaded patients. Br J Haematol 1979, 43:1-5.
    • (1979) Br J Haematol , vol.43 , pp. 1-5
    • Jacobs, A.1
  • 166
    • 84891467222 scopus 로고    scopus 로고
    • Serum TNF alpha levels: a prognostic marker for assessment of severity of malaria
    • Kinra P, Dutta V Serum TNF alpha levels: a prognostic marker for assessment of severity of malaria. Trop Biomed 2013, 30:645-653.
    • (2013) Trop Biomed , vol.30 , pp. 645-653
    • Kinra, P.1    Dutta, V.2
  • 167
    • 0027221836 scopus 로고
    • Anti-TNF therapy inhibits fever in cerebral malaria
    • Kwiatkowski D, Molyneux ME, Stephens S, et al. Anti-TNF therapy inhibits fever in cerebral malaria. Q J Med 1993, 86:91-98.
    • (1993) Q J Med , vol.86 , pp. 91-98
    • Kwiatkowski, D.1    Molyneux, M.E.2    Stephens, S.3
  • 168
    • 84940435295 scopus 로고    scopus 로고
    • Innate immunity against Leishmania infections
    • Gurung P, Kanneganti TD Innate immunity against Leishmania infections. Cell Microbiol 2015, 17:1286-1294.
    • (2015) Cell Microbiol , vol.17 , pp. 1286-1294
    • Gurung, P.1    Kanneganti, T.D.2
  • 169
    • 84940914561 scopus 로고    scopus 로고
    • Sequential chemoimmunotherapy of experimental visceral leishmaniasis using a single low dose of liposomal amphotericin B and a novel DNA vaccine candidate
    • Seifert K, Juhls C, Salguero FJ, Croft SL Sequential chemoimmunotherapy of experimental visceral leishmaniasis using a single low dose of liposomal amphotericin B and a novel DNA vaccine candidate. Antimicrob Agents Chemother 2015, 59:5819-5823.
    • (2015) Antimicrob Agents Chemother , vol.59 , pp. 5819-5823
    • Seifert, K.1    Juhls, C.2    Salguero, F.J.3    Croft, S.L.4
  • 170
    • 84959171712 scopus 로고    scopus 로고
    • Pathogen- and host-directed antileishmanial effects mediated by polyhexanide (PHMB)
    • Firdessa R, Good L, Amstalden MC, et al. Pathogen- and host-directed antileishmanial effects mediated by polyhexanide (PHMB). PLoS Negl Trop Dis 2015, 9:e0004041.
    • (2015) PLoS Negl Trop Dis , vol.9
    • Firdessa, R.1    Good, L.2    Amstalden, M.C.3
  • 171
    • 84946543514 scopus 로고    scopus 로고
    • Chagas' disease
    • Bern C Chagas' disease. N Engl J Med 2015, 373:456-466.
    • (2015) N Engl J Med , vol.373 , pp. 456-466
    • Bern, C.1
  • 174
    • 84925358239 scopus 로고    scopus 로고
    • CD4+ T cell hyporesponsiveness after repeated exposure to Schistosoma mansoni larvae is dependent upon interleukin-10
    • Prendergast CT, Sanin DE, Cook PC, Mountford AP CD4+ T cell hyporesponsiveness after repeated exposure to Schistosoma mansoni larvae is dependent upon interleukin-10. Infect Immun 2015, 83:1418-1430.
    • (2015) Infect Immun , vol.83 , pp. 1418-1430
    • Prendergast, C.T.1    Sanin, D.E.2    Cook, P.C.3    Mountford, A.P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.