-
1
-
-
84885902720
-
-
U.S. Food and Drug Administration, Silver Spring, MD
-
U.S. Food and Drug Administration. 2013. FDA news release. U.S. Food and Drug Administration, Silver Spring, MD. www.fda.gov/NewsEvents /Newsroom/PressAnnouncements/ucm333695.htm.
-
(2013)
FDA News Release
-
-
U.S. Food and Drug Administration1
-
2
-
-
19944429772
-
A diarylquinoline drug active on the ATP synthase of Mycobacterium tuberculosis
-
Andries K, Verhasselt P, Guillemont J, Göhlmann HW, Neefs JM, Winkler H, Van Gestel J, Timmerman P, Zhu M, Lee E, Williams P, de Chaffoy D, Huitric E, Hoffner S, Cambau E, Truffot-Pernot C, Lounis N, Jarlier V. 2005. A diarylquinoline drug active on the ATP synthase of Mycobacterium tuberculosis. Science 307:223-227. http://dx.doi.org/10 .1126/science.1106753.
-
(2005)
Science
, vol.307
, pp. 223-227
-
-
Andries, K.1
Verhasselt, P.2
Guillemont, J.3
Göhlmann, H.W.4
Neefs, J.M.5
Winkler, H.6
Van Gestel, J.7
Timmerman, P.8
Zhu, M.9
Lee, E.10
Williams, P.11
De Chaffoy, D.12
Huitric, E.13
Hoffner, S.14
Cambau, E.15
Truffot-Pernot, C.16
Lounis, N.17
Jarlier, V.18
-
3
-
-
84920163201
-
Sirturo product information for health care providers
-
Titusville, NJ
-
Janssen Therapeutics. 2013. Sirturo product information for health care providers. Janssen Therapeutics, Titusville, NJ.
-
(2013)
Janssen Therapeutics
-
-
Janssen Therapeutics1
-
4
-
-
84941182040
-
The use of bedaquiline in regimens to treat drugresistant and drug-susceptible tuberculosis: A perspective from tuber-culosis-affected communities
-
in press
-
Mingote LR, Namutamba D, Apina F, Barnabas N, Contreras C, Elnour T, Frick MW, Lee C, Seaworth B, Shelly D, Skipper N, Dos Santos Filho ET. The use of bedaquiline in regimens to treat drugresistant and drug-susceptible tuberculosis: a perspective from tuber-culosis-affected communities. Lancet, in press. http://dx.doi.org/10 .1016/S0140-6736(14)60523-7.
-
Lancet
-
-
Mingote, L.R.1
Namutamba, D.2
Apina, F.3
Barnabas, N.4
Contreras, C.5
Elnour, T.6
Frick, M.W.7
Lee, C.8
Seaworth, B.9
Shelly, D.10
Skipper, N.11
Dos Santos Filho, E.T.12
-
5
-
-
66649090346
-
The diarylquinoline TMC207 for multidrug-resistant tuberculosis
-
Diacon AH, Pym A, Grobusch M, Patientia R, Rustomjee R, Page-Shipp L, Pistorius C, Krause R, Bogoshi M, Churchyard G, Venter A, Allen J, Palomino JC, De Marez T, van Heeswijk RP, Lounis N, Meyvisch P, Verbeeck J, Parys W, de Beule K, Andries K, Mc Neeley DF. 2009. The diarylquinoline TMC207 for multidrug-resistant tuberculosis. N Engl J Med 360:2397-2405. http://dx.doi.org/10.1056/NEJMoa0808427.
-
(2009)
N Engl J Med
, vol.360
, pp. 2397-2405
-
-
Diacon, A.H.1
Pym, A.2
Grobusch, M.3
Patientia, R.4
Rustomjee, R.5
Page-Shipp, L.6
Pistorius, C.7
Krause, R.8
Bogoshi, M.9
Churchyard, G.10
Venter, A.11
Allen, J.12
Palomino, J.C.13
De Marez, T.14
Van Heeswijk, R.P.15
Lounis, N.16
Meyvisch, P.17
Verbeeck, J.18
Parys, W.19
De Beule, K.20
Andries, K.21
Mc Neeley, D.F.22
more..
-
6
-
-
80052580674
-
Efflux as a mechanism for drug resistance in Mycobacterium tuberculosis
-
da Silva PE, Von Groll A, Martin A, Palomino JC. 2011. Efflux as a mechanism for drug resistance in Mycobacterium tuberculosis. FEMS Immunol Med Microbiol 63:1-9. http://dx.doi.org/10.1111/j.1574-695X .2011.00831.x.
-
(2011)
FEMS Immunol Med Microbiol
, vol.63
, pp. 1-9
-
-
Da Silva, P.E.1
Von Groll, A.2
Martin, A.3
Palomino, J.C.4
-
7
-
-
80051572614
-
Rifampicin reduces susceptibility to ofloxacin in rifampicin-resistant Mycobacterium tuberculosis through efflux
-
Louw GE, Warren RM, Gey van Pittius NC, Leon R, Jimenez A, Hernandez-Pando R, McEvoy CR, Grobbelaar M, Murray M, van Helden PD, Victor TC. 2011. Rifampicin reduces susceptibility to ofloxacin in rifampicin-resistant Mycobacterium tuberculosis through efflux.Am J Respir Crit Care Med 184:269-276. http://dx.doi.org/10.1164/rccm .201011-1924OC.
-
(2011)
Am J Respir Crit Care Med
, vol.184
, pp. 269-276
-
-
Louw, G.E.1
Warren, R.M.2
Gey Van Pittius, N.C.3
Leon, R.4
Jimenez, A.5
Hernandez-Pando, R.6
McEvoy, C.R.7
Grobbelaar, M.8
Murray, M.9
Van Helden, P.D.10
Victor, T.C.11
-
8
-
-
79953279193
-
Drug tolerance in replicating mycobacteria mediated by a macrophage-induced efflux mechanism
-
Adams KN, Takaki K, Connolly LE, Wiedenhoft H, Winglee K, Humbert O, Edelstein PH, Cosma CL, Ramakrishnan L. 2011. Drug tolerance in replicating mycobacteria mediated by a macrophage-induced efflux mechanism. Cell 145:39-53. http://dx.doi.org/10.1016/j.cell.2011.02.022.
-
(2011)
Cell
, vol.145
, pp. 39-53
-
-
Adams, K.N.1
Takaki, K.2
Connolly, L.E.3
Wiedenhoft, H.4
Winglee, K.5
Humbert, O.6
Edelstein, P.H.7
Cosma, C.L.8
Ramakrishnan, L.9
-
9
-
-
84883514966
-
Acceleration of tuberculosis treatment by adjunctive therapy with verapamil as an efflux inhibitor
-
Gupta S, Tyagi S, Almeida DV, Maiga MC, Ammerman NC, Bishai WR. 2013. Acceleration of tuberculosis treatment by adjunctive therapy with verapamil as an efflux inhibitor.AmJ Respir Crit Care Med 188:600-607. http://dx.doi.org/10.1164/rccm.201304-0650OC.
-
(2013)
Amj Respir Crit Care Med
, vol.188
, pp. 600-607
-
-
Gupta, S.1
Tyagi, S.2
Almeida, D.V.3
Maiga, M.C.4
Ammerman, N.C.5
Bishai, W.R.6
-
10
-
-
84891543452
-
Efflux inhibition with verapamil potentiates bedaquiline in Mycobacterium tuberculosis
-
Gupta S, Cohen KA, Winglee K, Maiga M, Diarra B, Bishai WR. 2014. Efflux inhibition with verapamil potentiates bedaquiline in Mycobacterium tuberculosis. Antimicrob Agents Chemother 58:574-576. http://dx .doi.org/10.1128/AAC.01462-13.
-
(2014)
Antimicrob Agents Chemother
, vol.58
, pp. 574-576
-
-
Gupta, S.1
Cohen, K.A.2
Winglee, K.3
Maiga, M.4
Diarra, B.5
Bishai, W.R.6
-
11
-
-
84904255286
-
Acquired resistance of Mycobacterium tuberculosis to bedaquiline
-
Andries K, Villellas C, Coeck N, Thys K, Gevers T, Vranckx L, Lounis N, de Jong BC, Koul A. 2014. Acquired resistance of Mycobacterium tuberculosis to bedaquiline. PLoS One 9:e102135. http://dx.doi.org/10 .1371/journal.pone.0102135.
-
(2014)
PLoS One
, vol.9
, pp. e102135
-
-
Andries, K.1
Villellas, C.2
Coeck, N.3
Thys, K.4
Gevers, T.5
Vranckx, L.6
Lounis, N.7
De Jong, B.C.8
Koul, A.9
-
12
-
-
84876269304
-
Randomized dose-ranging study of the 14-day early bactericidal activity of bedaquiline (TMC207) in patients with sputum microscopy smear-positive pulmonary tuberculosis
-
Diacon AH, Dawson R, Von Groote-Bidlingmaier F, Symons G, Venter A, Donald PR, Conradie A, Erondu N, Ginsberg AM, Egizi E, Winter H, Becker P, Mendel CM. 2013. Randomized dose-ranging study of the 14-day early bactericidal activity of bedaquiline (TMC207) in patients with sputum microscopy smear-positive pulmonary tuberculosis. Antimicrob Agents Chemother 57:2199-2203. http://dx.doi.org/10.1128 /AAC.02243-12.
-
(2013)
Antimicrob Agents Chemother
, vol.57
, pp. 2199-2203
-
-
Diacon, A.H.1
Dawson, R.2
Von Groote-Bidlingmaier, F.3
Symons, G.4
Venter, A.5
Donald, P.R.6
Conradie, A.7
Erondu, N.8
Ginsberg, A.M.9
Egizi, E.10
Winter, H.11
Becker, P.12
Mendel, C.M.13
-
13
-
-
0024385229
-
Reversal of drug resistance in Trypanosoma cruzi and Leishmania donovani by verapamil
-
Neal RA, van Bueren J, McCoy NG, Iwobi M. 1989. Reversal of drug resistance in Trypanosoma cruzi and Leishmania donovani by verapamil. Trans R Soc Trop Med Hyg 83:197-198. http://dx.doi.org/10.1016/0035 -9203(89)90642-1.
-
(1989)
Trans R Soc Trop Med Hyg
, vol.83
, pp. 197-198
-
-
Neal, R.A.1
Van Bueren, J.2
McCoy, N.G.3
Iwobi, M.4
-
14
-
-
0023137728
-
Reversal of chloroquine resistance in Plasmodium falciparum by verapamil
-
Martin SK, Oduola AM, Milhous WK. 1987. Reversal of chloroquine resistance in Plasmodium falciparum by verapamil. Science 235:899-901. http://dx.doi.org/10.1126/science.3544220.
-
(1987)
Science
, vol.235
, pp. 899-901
-
-
Martin, S.K.1
Oduola, A.M.2
Milhous, W.K.3
-
15
-
-
84861140844
-
Randomized pilot trial of eight weeks of bedaquiline (TMC207) treatment for multidrugresistant tuberculosis: Long-term outcome, tolerability, and effect on emergence of drug resistance
-
Diacon AH, Donald PR, Pym A, Grobusch M, Patientia RF, Mahanyele R, Bantubani N, Narasimooloo R, De Marez T, van Heeswijk R, Lounis N, Meyvisch P, Andries K, McNeeley DF. 2012. Randomized pilot trial of eight weeks of bedaquiline (TMC207) treatment for multidrugresistant tuberculosis: long-term outcome, tolerability, and effect on emergence of drug resistance. Antimicrob Agents Chemother 56:3271-3276. http://dx.doi.org/10.1128/AAC.06126-11.
-
(2012)
Antimicrob Agents Chemother
, vol.56
, pp. 3271-3276
-
-
Diacon, A.H.1
Donald, P.R.2
Pym, A.3
Grobusch, M.4
Patientia, R.F.5
Mahanyele, R.6
Bantubani, N.7
Narasimooloo, R.8
De Marez, T.9
Van Heeswijk, R.10
Lounis, N.11
Meyvisch, P.12
Andries, K.13
McNeeley, D.F.14
-
16
-
-
0019401163
-
Systemic availability of oral verapamil and effect on PR interval in man
-
Johnston A, Burgess CD, Hamer J. 1981. Systemic availability of oral verapamil and effect on PR interval in man. Br J Clin Pharmacol 12:397-400. http://dx.doi.org/10.1111/j.1365-2125.1981.tb01233.x.
-
(1981)
Br J Clin Pharmacol
, vol.12
, pp. 397-400
-
-
Johnston, A.1
Burgess, C.D.2
Hamer, J.3
-
17
-
-
77955839656
-
Robust anti-arrhythmic efficacy of verapamil and flunarizine against dofetilide-induced TdP arrhythmias is based upon a shared and a different mode of action
-
Oros A, Houtman MJ, Neco P, Gomez AM, Rajamani S, Oosterhoff P, Attevelt NJ, Beekman JD, van der Heyden MA, Ver Donck L, Belardinelli L, Richard S, Antoons G, Vos MA, CONTICA Investigators. 2010. Robust anti-arrhythmic efficacy of verapamil and flunarizine against dofetilide-induced TdP arrhythmias is based upon a shared and a different mode of action. Br J Pharmacol 161:162-175. http://dx.doi.org /10.1111/j.1476-5381.2010.00883.x.
-
(2010)
Br J Pharmacol
, vol.161
, pp. 162-175
-
-
CONTICA Investigators1
Oros, A.2
Houtman, M.J.3
Neco, P.4
Gomez, A.M.5
Rajamani, S.6
Oosterhoff, P.7
Attevelt, N.J.8
Beekman, J.D.9
Van Der Heyden, M.A.10
Ver Donck, L.11
Belardinelli, L.12
Richard, S.13
Antoons, G.14
Vos, M.A.15
-
18
-
-
0030466312
-
Anticholinergic overdose induced torsade de pointes successfully treated with verapamil
-
Liao WB, Bullard MJ, Kuo CT, Hsiao CT, Chu PH, Chiang CW. 1996. Anticholinergic overdose induced torsade de pointes successfully treated with verapamil. Jpn Heart J 37:925-931. http://dx.doi.org/10 .1536/ihj.37.925.
-
(1996)
Jpn Heart J
, vol.37
, pp. 925-931
-
-
Liao, W.B.1
Bullard, M.J.2
Kuo, C.T.3
Hsiao, C.T.4
Chu, P.H.5
Chiang, C.W.6
-
19
-
-
0028839535
-
Effects of verapamil and propranolol on early afterdepolarizations and ventricular arrhythmias induced by epinephrine in congenital long QT syndrome
-
Shimizu W, Ohe T, Kurita T, Kawade M, Arakaki Y, Aihara N, Kamakura S, Kamiya T, Shimomura K. 1995. Effects of verapamil and propranolol on early afterdepolarizations and ventricular arrhythmias induced by epinephrine in congenital long QT syndrome. JAmColl Cardiol 26:1299-1309. http://dx.doi.org/10.1016/0735-1097(95)00313-4.
-
(1995)
JAmColl Cardiol
, vol.26
, pp. 1299-1309
-
-
Shimizu, W.1
Ohe, T.2
Kurita, T.3
Kawade, M.4
Arakaki, Y.5
Aihara, N.6
Kamakura, S.7
Kamiya, T.8
Shimomura, K.9
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