Phenylbutyrate induces cathelicidin expression via the vitamin D receptor: Linkage to inflammatory and growth factor cytokines pathways

Molecular Immunology

Volumn 63, Issue 2, 2015, Pages 530-539

  Kulkarni, Nikhil N ^a   Yi, Zhiqian ^a   Huehnken, Carolin ^a   Agerberth, Birgitta ^b   Gudmundsson, Gudmundur H ^a  

^a UNIVERSITY OF ICELAND   (Iceland)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Antimicrobial peptides; CAMP gene; LL 37, hBD 1, Pseudomonas aeruginosa

Indexed keywords

4 PHENYLBUTYRIC ACID; CATHELICIDIN ANTIMICROBIAL PEPTIDE LL 37; CD14 ANTIGEN; COLECALCIFEROL; CYCLIC AMP; CYTOKINE; EPIDERMAL GROWTH FACTOR RECEPTOR; FLAGELLIN; INTERLEUKIN 8; SMALL INTERFERING RNA; TOLL LIKE RECEPTOR 5; TRANSFORMING GROWTH FACTOR ALPHA; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2; TUMOR NECROSIS FACTOR ALPHA; VITAMIN D RECEPTOR; 4-PHENYLBUTYRIC ACID; ANTIMICROBIAL CATIONIC PEPTIDE; ARYLBUTYRIC ACID DERIVATIVE; BETA DEFENSIN; CALCITRIOL RECEPTOR; CAP18 LIPOPOLYSACCHARIDE-BINDING PROTEIN; COLECALCIFEROL 24 HYDROXYLASE; DEFB1 PROTEIN, HUMAN; LIGAND; MESSENGER RNA; SIGNAL PEPTIDE;

ARTICLE; EPITHELIUM CELL; GENE EXPRESSION; GENE INDUCTION; HUMAN; HUMAN CELL; INNATE IMMUNITY; NUCLEOTIDE SEQUENCE; PSEUDOMONAS AERUGINOSA; UPREGULATION; CELL LINE; DRUG EFFECTS; GENE SILENCING; GENETICS; GROWTH, DEVELOPMENT AND AGING; INFLAMMATION; METABOLISM; MICROBIAL SENSITIVITY TEST; PATHOLOGY; SIGNAL TRANSDUCTION;

PSEUDOMONAS AERUGINOSA;

ANTIMICROBIAL CATIONIC PEPTIDES; BETA-DEFENSINS; CELL LINE; CHOLECALCIFEROL; CYTOKINES; FLAGELLIN; GENE SILENCING; HUMANS; INFLAMMATION; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LIGANDS; MICROBIAL SENSITIVITY TESTS; PHENYLBUTYRATES; PSEUDOMONAS AERUGINOSA; RECEPTORS, CALCITRIOL; RNA, MESSENGER; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 5; UP-REGULATION; VITAMIN D3 24-HYDROXYLASE;

EID: 84912051287     PISSN: 01615890     EISSN: 18729142     Source Type: Journal    
DOI: 10.1016/j.molimm.2014.10.007     Document Type: Article

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