PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

Nature

Volumn 443, Issue 7109, 2006, Pages 350-354

  Day, Cheryl L ^a,b,c   Kaufmann, Daniel E ^b   Kiepiela, Photini ^a   Brown, Julia A ^d   Moodley, Eshia S ^a   Reddy, Sharon ^a   Mackey, Elizabeth W ^b   Miller, Joseph D ^e   Leslie, Alasdair J ^c   DePierres, Chantal ^a   Mncube, Zenele ^a   Duraiswamy, Jaikumar ^e   Zhu, Baogong ^d   Eichbaum, Quentin ^b   Altfeld, Marcus ^b   Wherry, E John ^f   Coovadia, Hoosen M ^a   Goulder, Philip J R ^a,b,c   Klenerman, Paul ^c   Ahmed, Rafi ^e   Freeman, Gordon J ^d   Walker, Bruce D ^a,b,g   more..

^a UNIVERSITY OF KWAZULU NATAL   (South Africa)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d HARVARD MEDICAL SCHOOL   (United States)

^e EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f WISTAR INSTITUTE   (United States)

^g HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIODIVERSITY; CELLS; DATA ACQUISITION; ENZYME INHIBITION; IMMUNOLOGY; VIRUSES;

HUMAN IMMUNODEFICIENCY VIRUS (HIV); MAJOR HISTOCOMPATIBILITY COMPLEX (MHC); PROGRAMMED DEATH 1 (PD-1);

CELL CULTURE;

ANTIBODY; CD8 ANTIGEN; CYTOKINE; INHIBITORY RECEPTOR PROGRAMMED DEATH 1; INHIBITORY RECEPTOR PROGRAMMED DEATH 1 LIGAND 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; TETRAMER; UNCLASSIFIED DRUG;

ANTIBODY; DISEASE; GENE EXPRESSION; HUMAN IMMUNODEFICIENCY VIRUS; MAJOR HISTOCOMPATIBILITY COMPLEX; VIRAL DISEASE;

ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL SURFACE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE COURSE; DRUG TARGETING; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOREGULATION; LYMPHOCYTE FUNCTION; NONHUMAN; PERSISTENT INFECTION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; VIRUS LOAD;

HUMAN IMMUNODEFICIENCY VIRUS;

EID: 33748947326     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature05115     Document Type: Article

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