메뉴 건너뛰기




Volumn 21, Issue 42, 2015, Pages 11984-12002

Progress in the development of vaccines for hepatitis C virus infection

Author keywords

Hepatitis C virus; Hepatitis C virus infection; Preventive vaccine; Therapeutic vaccine

Indexed keywords

DNA VACCINE; HEPATITIS C VACCINE; PEPTIDE VACCINE; RECOMBINANT PROTEIN; RECOMBINANT VACCINE; VIRUS VECTOR; HEPATITIS VACCINE;

EID: 84947425793     PISSN: 10079327     EISSN: 22192840     Source Type: Journal    
DOI: 10.3748/wjg.v21.i42.11984     Document Type: Article
Times cited : (30)

References (227)
  • 2
    • 33644875265 scopus 로고    scopus 로고
    • Spontaneous viral clearance following acute hepatitis C infection: A systematic review of longitudinal studies
    • PMID: 16364080
    • Micallef JM, Kaldor JM, Dore GJ. Spontaneous viral clearance following acute hepatitis C infection: a systematic review of longitudinal studies. J Viral Hepat 2006; 13: 34-41 [PMID: 16364080]
    • (2006) J Viral Hepat , vol.13 , pp. 34-41
    • Micallef, J.M.1    Kaldor, J.M.2    Dore, G.J.3
  • 5
    • 0343527271 scopus 로고    scopus 로고
    • HCV: Epidemiology, modes of transmission and prevention of spread
    • PMID: 10890316
    • Pradat P, Trépo C. HCV: epidemiology, modes of transmission and prevention of spread. Baillieres Best Pract Res Clin Gastroenterol 2000; 14: 201-210 [PMID: 10890316]
    • (2000) Baillieres Best Pract Res Clin Gastroenterol , vol.14 , pp. 201-210
    • Pradat, P.1    Trépo, C.2
  • 6
    • 77954682191 scopus 로고    scopus 로고
    • Mother-to-infant HCV transmission. Can we influence the frequency and the course of the infection?
    • PMID: 20509564
    • Aniszewska M, Kowalik-Mikołajewska B, Pokorska-Lis M, Kalinowska M, Marczyńskai M. [Mother-to-infant HCV transmission. Can we influence the frequency and the course of the infection?]. Przegl Lek 2010; 67: 9-12 [PMID: 20509564]
    • (2010) Przegl Lek , vol.67 , pp. 9-12
    • Aniszewska, M.1    Kowalik-Mikołajewska, B.2    Pokorska-Lis, M.3    Kalinowska, M.4    Marczyńskai, M.5
  • 7
    • 0036264488 scopus 로고    scopus 로고
    • Isolation of a cDNA clone derived from a bloodborne non-A, non-B viral hepatitis genome [Science 1989; 244: 359-362]
    • PMID: 11983439
    • Farci P. Choo QL, Kuo G, Weiner AJ, Overby LR, Bradley DW, Houghton M. Isolation of a cDNA clone derived from a bloodborne non-A, non-B viral hepatitis genome [Science 1989; 244: 359-362]. J Hepatol 2002; 36: 582-585 [PMID: 11983439]
    • (2002) J Hepatol , vol.36 , pp. 582-585
    • Farci, P.1    Choo, Q.L.2    Kuo, G.3    Weiner, A.J.4    Overby, L.R.5    Bradley, D.W.6    Houghton, M.7
  • 8
    • 84867308646 scopus 로고    scopus 로고
    • Global burden of hepatitis C: Considerations for healthcare providers in the United States
    • PMID: 22715208
    • Averhoff FM, Glass N, Holtzman D. Global burden of hepatitis C: considerations for healthcare providers in the United States. Clin Infect Dis 2012; 55 Suppl 1: S10-S15 [PMID: 22715208]
    • (2012) Clin Infect Dis , vol.55 , pp. S10-S15
    • Averhoff, F.M.1    Glass, N.2    Holtzman, D.3
  • 9
    • 23944506014 scopus 로고    scopus 로고
    • Global epidemiology of hepatitis C virus infection
    • PMID: 16122679
    • Shepard CW, Finelli L, Alter MJ. Global epidemiology of hepatitis C virus infection. Lancet Infect Dis 2005; 5: 558-567 [PMID: 16122679]
    • (2005) Lancet Infect Dis , vol.5 , pp. 558-567
    • Shepard, C.W.1    Finelli, L.2    Alter, M.J.3
  • 10
    • 84876149257 scopus 로고    scopus 로고
    • Global epidemiology of hepatitis C virus infection: New estimates of agespecific antibody to HCV seroprevalence
    • PMID: 23172780
    • Mohd Hanafiah K, Groeger J, Flaxman AD, Wiersma ST. Global epidemiology of hepatitis C virus infection: new estimates of agespecific antibody to HCV seroprevalence. Hepatology 2013; 57: 1333-1342 [PMID: 23172780]
    • (2013) Hepatology , vol.57 , pp. 1333-1342
    • Mohd Hanafiah, K.1    Groeger, J.2    Flaxman, A.D.3    Wiersma, S.T.4
  • 11
    • 0033060563 scopus 로고    scopus 로고
    • Global surveillance and control of hepatitis C. Report of a WHO Consultation organized in collaboration with the Viral Hepatitis Prevention Board, Antwerp, Belgium
    • PMID: 10847128
    • Global surveillance and control of hepatitis C. Report of a WHO Consultation organized in collaboration with the Viral Hepatitis Prevention Board, Antwerp, Belgium. J Viral Hepat 1999; 6: 35-47 [PMID: 10847128 DOI: 10.1186/1743-422X-4-104]
    • (1999) J Viral Hepat , vol.6 , pp. 35-47
  • 12
    • 84879113095 scopus 로고    scopus 로고
    • Chronic hepatitis C virus (HCV) disease burden and cost in the United States
    • PMID: 23280550
    • Razavi H, Elkhoury AC, Elbasha E, Estes C, Pasini K, Poynard T, Kumar R. Chronic hepatitis C virus (HCV) disease burden and cost in the United States. Hepatology 2013; 57: 2164-2170 [PMID: 23280550]
    • (2013) Hepatology , vol.57 , pp. 2164-2170
    • Razavi, H.1    Elkhoury, A.C.2    Elbasha, E.3    Estes, C.4    Pasini, K.5    Poynard, T.6    Kumar, R.7
  • 13
    • 84914150658 scopus 로고    scopus 로고
    • Global epidemiology and genotype distribution of the hepatitis C virus infection
    • PMID: 25086286
    • Gower E, Estes C, Blach S, Razavi-Shearer K, Razavi H. Global epidemiology and genotype distribution of the hepatitis C virus infection. J Hepatol 2014; 61: S45-S57 [PMID: 25086286]
    • (2014) J Hepatol , vol.61 , pp. S45-S57
    • Gower, E.1    Estes, C.2    Blach, S.3    Razavi-Shearer, K.4    Razavi, H.5
  • 16
    • 0033406372 scopus 로고    scopus 로고
    • Hepatitis C: The clinical spectrum of the disease
    • PMID: 10622554
    • Marcellin P. Hepatitis C: the clinical spectrum of the disease. J Hepatol 1999; 31 Suppl 1: 9-16 [PMID: 10622554]
    • (1999) J Hepatol , vol.31 , pp. 9-16
    • Marcellin, P.1
  • 18
    • 79961216296 scopus 로고    scopus 로고
    • Hepatitis C virus E1 envelope glycoprotein interacts with apolipoproteins in facilitating entry into hepatocytes
    • PMID: 21735466
    • Mazumdar B, Banerjee A, Meyer K, Ray R. Hepatitis C virus E1 envelope glycoprotein interacts with apolipoproteins in facilitating entry into hepatocytes. Hepatology 2011; 54: 1149-1156 [PMID: 21735466]
    • (2011) Hepatology , vol.54 , pp. 1149-1156
    • Mazumdar, B.1    Banerjee, A.2    Meyer, K.3    Ray, R.4
  • 19
    • 84936932847 scopus 로고    scopus 로고
    • A novel small-molecule inhibitor of hepatitis C virus replication acts by suppressing signal transducer and activator of transcription 3
    • PMID: 25858355
    • Niu Y, Si Y, Li Y, Chi X, Li X, Liu X, Li D, Cheng M, Fan J, Si S, Yang W. A novel small-molecule inhibitor of hepatitis C virus replication acts by suppressing signal transducer and activator of transcription 3. J Antimicrob Chemother 2015; 70: 2013-2023 [PMID: 25858355]
    • (2015) J Antimicrob Chemother , vol.70 , pp. 2013-2023
    • Niu, Y.1    Si, Y.2    Li, Y.3    Chi, X.4    Li, X.5    Liu, X.6    Li, D.7    Cheng, M.8    Fan, J.9    Si, S.10    Yang, W.11
  • 21
    • 0026513651 scopus 로고
    • Internal ribosome entry site within hepatitis C virus RNA
    • PMID: 1310759
    • Tsukiyama-Kohara K, Iizuka N, Kohara M, Nomoto A. Internal ribosome entry site within hepatitis C virus RNA. J Virol 1992; 66: 1476-1483 [PMID: 1310759]
    • (1992) J Virol , vol.66 , pp. 1476-1483
    • Tsukiyama-Kohara, K.1    Iizuka, N.2    Kohara, M.3    Nomoto, A.4
  • 22
    • 0027153210 scopus 로고
    • Translation of human hepatitis C virus RNA in cultured cells is mediated by an internal ribosomebinding mechanism
    • PMID: 8388503
    • Wang C, Sarnow P, Siddiqui A. Translation of human hepatitis C virus RNA in cultured cells is mediated by an internal ribosomebinding mechanism. J Virol 1993; 67: 3338-3344 [PMID: 8388503]
    • (1993) J Virol , vol.67 , pp. 3338-3344
    • Wang, C.1    Sarnow, P.2    Siddiqui, A.3
  • 23
    • 0033920795 scopus 로고    scopus 로고
    • Replication of hepatitis C virus
    • PMID: 10859368
    • Bartenschlager R, Lohmann V. Replication of hepatitis C virus. J Gen Virol 2000; 81: 1631-1648 [PMID: 10859368]
    • (2000) J Gen Virol , vol.81 , pp. 1631-1648
    • Bartenschlager, R.1    Lohmann, V.2
  • 24
    • 0029938477 scopus 로고    scopus 로고
    • Identification of a highly conserved sequence element at the 3' terminus of hepatitis C virus genome RNA
    • PMID: 8648666
    • Kolykhalov AA, Feinstone SM, Rice CM. Identification of a highly conserved sequence element at the 3' terminus of hepatitis C virus genome RNA. J Virol 1996; 70: 3363-3371 [PMID: 8648666]
    • (1996) J Virol , vol.70 , pp. 3363-3371
    • Kolykhalov, A.A.1    Feinstone, S.M.2    Rice, C.M.3
  • 25
    • 0029927642 scopus 로고    scopus 로고
    • Structure of the 3' terminus of the hepatitis C virus genome
    • PMID: 8627816
    • Tanaka T, Kato N, Cho MJ, Sugiyama K, Shimotohno K. Structure of the 3' terminus of the hepatitis C virus genome. J Virol 1996; 70: 3307-3312 [PMID: 8627816]
    • (1996) J Virol , vol.70 , pp. 3307-3312
    • Tanaka, T.1    Kato, N.2    Cho, M.J.3    Sugiyama, K.4    Shimotohno, K.5
  • 26
    • 0033515094 scopus 로고    scopus 로고
    • In vivo analysis of the 3' untranslated region of the hepatitis C virus after in vitro mutagenesis of an infectious cDNA clone
    • PMID: 10051634
    • Yanagi M, St Claire M, Emerson SU, Purcell RH, Bukh J. In vivo analysis of the 3' untranslated region of the hepatitis C virus after in vitro mutagenesis of an infectious cDNA clone. Proc Natl Acad Sci USA 1999; 96: 2291-2295 [PMID: 10051634]
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 2291-2295
    • Yanagi, M.1    St Claire, M.2    Emerson, S.U.3    Purcell, R.H.4    Bukh, J.5
  • 27
    • 84880309916 scopus 로고    scopus 로고
    • Understanding the hepatitis C virus life cycle paves the way for highly effective therapies
    • PMID: 23836234
    • Scheel TK, Rice CM. Understanding the hepatitis C virus life cycle paves the way for highly effective therapies. Nat Med 2013; 19: 837-849 [PMID: 23836234]
    • (2013) Nat Med , vol.19 , pp. 837-849
    • Scheel, T.K.1    Rice, C.M.2
  • 28
    • 34249024924 scopus 로고    scopus 로고
    • Replication of hepatitis C virus
    • PMID: 17487147
    • Moradpour D, Penin F, Rice CM. Replication of hepatitis C virus. Nat Rev Microbiol 2007; 5: 453-463 [PMID: 17487147]
    • (2007) Nat Rev Microbiol , vol.5 , pp. 453-463
    • Moradpour, D.1    Penin, F.2    Rice, C.M.3
  • 30
    • 0034053296 scopus 로고    scopus 로고
    • Properties of the hepatitis C virus core protein: A structural protein that modulates cellular processes
    • PMID: 10718937
    • McLauchlan J. Properties of the hepatitis C virus core protein: a structural protein that modulates cellular processes. J Viral Hepat 2000; 7: 2-14 [PMID: 10718937]
    • (2000) J Viral Hepat , vol.7 , pp. 2-14
    • McLauchlan, J.1
  • 31
    • 81855190655 scopus 로고    scopus 로고
    • Advances in hepatitis C virus vaccines, Part one: Advances in basic knowledge for hepatitis C virus vaccine design
    • PMID: 22022980
    • Roohvand F, Kossari N. Advances in hepatitis C virus vaccines, Part one: Advances in basic knowledge for hepatitis C virus vaccine design. Expert Opin Ther Pat 2011; 21: 1811-1830 [PMID: 22022980]
    • (2011) Expert Opin Ther Pat , vol.21 , pp. 1811-1830
    • Roohvand, F.1    Kossari, N.2
  • 32
    • 79951803564 scopus 로고    scopus 로고
    • Characterization of antibodymediated neutralization directed against the hypervariable region 1 of hepatitis C virus E2 glycoprotein
    • PMID: 21084495
    • Vieyres G, Dubuisson J, Patel AH. Characterization of antibodymediated neutralization directed against the hypervariable region 1 of hepatitis C virus E2 glycoprotein. J Gen Virol 2011; 92: 494-506 [PMID: 21084495]
    • (2011) J Gen Virol , vol.92 , pp. 494-506
    • Vieyres, G.1    Dubuisson, J.2    Patel, A.H.3
  • 33
    • 0037593310 scopus 로고    scopus 로고
    • The proteins of the Hepatitis C virus: Their features and interactions with intracellular protein phosphorylation
    • PMID: 12827459
    • Schulze zur Wiesch J, Schmitz H, Borowski E, Borowski P. The proteins of the Hepatitis C virus: their features and interactions with intracellular protein phosphorylation. Arch Virol 2003; 148: 1247-1267 [PMID: 12827459]
    • (2003) Arch Virol , vol.148 , pp. 1247-1267
    • Schulzezur Wiesch, J.1    Schmitz, H.2    Borowski, E.3    Borowski, P.4
  • 34
    • 46749154594 scopus 로고    scopus 로고
    • Immune responses during acute and chronic infection with hepatitis C virus
    • PMID: 18514579
    • Ishii S, Koziel MJ. Immune responses during acute and chronic infection with hepatitis C virus. Clin Immunol 2008; 128: 133-147 [PMID: 18514579]
    • (2008) Clin Immunol , vol.128 , pp. 133-147
    • Ishii, S.1    Koziel, M.J.2
  • 35
    • 70350461709 scopus 로고    scopus 로고
    • Characterization of the cellular immune response in hepatitis C virus infection
    • PMID: 19378287
    • Zhang X, Dou J, Germann MW. Characterization of the cellular immune response in hepatitis C virus infection. Med Res Rev 2009; 29: 843-866 [PMID: 19378287]
    • (2009) Med Res Rev , vol.29 , pp. 843-866
    • Zhang, X.1    Dou, J.2    Germann, M.W.3
  • 36
    • 34249792383 scopus 로고    scopus 로고
    • Allelic variation in the hepatitis C virus NS4B protein dramatically influences RNA replication
    • PMID: 17360748
    • Blight KJ. Allelic variation in the hepatitis C virus NS4B protein dramatically influences RNA replication. J Virol 2007; 81: 5724-5736 [PMID: 17360748]
    • (2007) J Virol , vol.81 , pp. 5724-5736
    • Blight, K.J.1
  • 37
    • 42949145532 scopus 로고    scopus 로고
    • Regulation of hepatitis C virion production via phosphorylation of the NS5A protein
    • PMID: 18369478
    • Tellinghuisen TL, Foss KL, Treadaway J. Regulation of hepatitis C virion production via phosphorylation of the NS5A protein. PLoS Pathog 2008; 4: e1000032 [PMID: 18369478]
    • (2008) PLoS Pathog , vol.4 , pp. e1000032
    • Tellinghuisen, T.L.1    Foss, K.L.2    Treadaway, J.3
  • 38
    • 0028945033 scopus 로고
    • Genetic heterogeneity of hepatitis C virus: Quasispecies and genotypes
    • PMID: 7597443
    • Bukh J, Miller RH, Purcell RH. Genetic heterogeneity of hepatitis C virus: quasispecies and genotypes. Semin Liver Dis 1995; 15: 41-63 [PMID: 7597443]
    • (1995) Semin Liver Dis , vol.15 , pp. 41-63
    • Bukh, J.1    Miller, R.H.2    Purcell, R.H.3
  • 39
    • 84873706272 scopus 로고    scopus 로고
    • Immunity and hepatitis C: A review
    • PMID: 23180007
    • Terilli RR, Cox AL. Immunity and hepatitis C: a review. Curr HIV/AIDS Rep 2013; 10: 51-58 [PMID: 23180007]
    • (2013) Curr HIV/AIDS Rep , vol.10 , pp. 51-58
    • Terilli, R.R.1    Cox, A.L.2
  • 40
    • 77249132637 scopus 로고    scopus 로고
    • Recognition of viruses by cytoplasmic sensors
    • PMID: 20061127
    • Wilkins C, Gale M. Recognition of viruses by cytoplasmic sensors. Curr Opin Immunol 2010; 22: 41-47 [PMID: 20061127]
    • (2010) Curr Opin Immunol , vol.22 , pp. 41-47
    • Wilkins, C.1    Gale, M.2
  • 41
    • 84896690188 scopus 로고    scopus 로고
    • Activation and evasion of antiviral innate immunity by hepatitis C virus
    • PMID: 24184198
    • Horner SM. Activation and evasion of antiviral innate immunity by hepatitis C virus. J Mol Biol 2014; 426: 1198-1209 [PMID: 24184198]
    • (2014) J Mol Biol , vol.426 , pp. 1198-1209
    • Horner, S.M.1
  • 42
    • 47149105036 scopus 로고    scopus 로고
    • Toll-like receptors and adaptor molecules in liver disease: Update
    • PMID: 18506843
    • Seki E, Brenner DA. Toll-like receptors and adaptor molecules in liver disease: update. Hepatology 2008; 48: 322-335 [PMID: 18506843]
    • (2008) Hepatology , vol.48 , pp. 322-335
    • Seki, E.1    Brenner, D.A.2
  • 43
    • 84863393834 scopus 로고    scopus 로고
    • Activation of chemokine and inflammatory cytokine response in hepatitis C virus-infected hepatocytes depends on Toll-like receptor 3 sensing of hepatitis C virus double-stranded RNA intermediates
    • PMID: 22030901
    • Li K, Li NL, Wei D, Pfeffer SR, Fan M, Pfeffer LM. Activation of chemokine and inflammatory cytokine response in hepatitis C virus-infected hepatocytes depends on Toll-like receptor 3 sensing of hepatitis C virus double-stranded RNA intermediates. Hepatology 2012; 55: 666-675 [PMID: 22030901]
    • (2012) Hepatology , vol.55 , pp. 666-675
    • Li, K.1    Li, N.L.2    Wei, D.3    Pfeffer, S.R.4    Fan, M.5    Pfeffer, L.M.6
  • 44
    • 70349278409 scopus 로고    scopus 로고
    • Tolllike receptor 3 mediates establishment of an antiviral state against hepatitis C virus in hepatoma cells
    • PMID: 19625408
    • Wang N, Liang Y, Devaraj S, Wang J, Lemon SM, Li K. Tolllike receptor 3 mediates establishment of an antiviral state against hepatitis C virus in hepatoma cells. J Virol 2009; 83: 9824-9834 [PMID: 19625408]
    • (2009) J Virol , vol.83 , pp. 9824-9834
    • Wang, N.1    Liang, Y.2    Devaraj, S.3    Wang, J.4    Lemon, S.M.5    Li, K.6
  • 45
    • 77952127743 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells sense hepatitis C virus-infected cells, produce interferon, and inhibit infection
    • PMID: 20231459
    • Takahashi K, Asabe S, Wieland S, Garaigorta U, Gastaminza P, Isogawa M, Chisari FV. Plasmacytoid dendritic cells sense hepatitis C virus-infected cells, produce interferon, and inhibit infection. Proc Natl Acad Sci USA 2010; 107: 7431-7436 [PMID: 20231459]
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 7431-7436
    • Takahashi, K.1    Asabe, S.2    Wieland, S.3    Garaigorta, U.4    Gastaminza, P.5    Isogawa, M.6    Chisari, F.V.7
  • 46
  • 47
    • 84878237993 scopus 로고    scopus 로고
    • Activation and regulation of the inflammasomes
    • PMID: 23702978
    • Latz E, Xiao TS, Stutz A. Activation and regulation of the inflammasomes. Nat Rev Immunol 2013; 13: 397-411 [PMID: 23702978]
    • (2013) Nat Rev Immunol , vol.13 , pp. 397-411
    • Latz, E.1    Xiao, T.S.2    Stutz, A.3
  • 48
    • 84880412360 scopus 로고    scopus 로고
    • Hepatic stellate cells, liver innate immunity, and hepatitis C virus
    • PMID: 23855305
    • Wang Y, Li J, Wang X, Sang M, Ho W. Hepatic stellate cells, liver innate immunity, and hepatitis C virus. J Gastroenterol Hepatol 2013; 28 Suppl 1: 112-115 [PMID: 23855305]
    • (2013) J Gastroenterol Hepatol , vol.28 , pp. 112-115
    • Wang, Y.1    Li, J.2    Wang, X.3    Sang, M.4    Ho, W.5
  • 49
    • 84872396542 scopus 로고    scopus 로고
    • Innate immune responses in hepatitis C virus infection
    • PMID: 22868377
    • Li K, Lemon SM. Innate immune responses in hepatitis C virus infection. Semin Immunopathol 2013; 35: 53-72 [PMID: 22868377]
    • (2013) Semin Immunopathol , vol.35 , pp. 53-72
    • Li, K.1    Lemon, S.M.2
  • 50
    • 78649708165 scopus 로고    scopus 로고
    • IL28B and the control of hepatitis C virus infection
    • PMID: 20950615
    • Balagopal A, Thomas DL, Thio CL. IL28B and the control of hepatitis C virus infection. Gastroenterology 2010; 139: 1865-1876 [PMID: 20950615]
    • (2010) Gastroenterology , vol.139 , pp. 1865-1876
    • Balagopal, A.1    Thomas, D.L.2    Thio, C.L.3
  • 54
    • 54749149734 scopus 로고    scopus 로고
    • Regulatory polymorphisms in the interleukin-18 promoter are associated with hepatitis C virus clearance
    • PMID: 18781864
    • An P, Thio CL, Kirk GD, Donfield S, Goedert JJ, Winkler CA. Regulatory polymorphisms in the interleukin-18 promoter are associated with hepatitis C virus clearance. J Infect Dis 2008; 198: 1159-1165 [PMID: 18781864]
    • (2008) J Infect Dis , vol.198 , pp. 1159-1165
    • An, P.1    Thio, C.L.2    Kirk, G.D.3    Donfield, S.4    Goedert, J.J.5    Winkler, C.A.6
  • 57
    • 0029882401 scopus 로고    scopus 로고
    • Transmission of hepatitis C via both erythrocyte and platelet transfusions from a single donor in serological window-phase of hepatitis C
    • PMID: 8837359
    • Widell A, Elmud H, Persson MH, Jonsson M. Transmission of hepatitis C via both erythrocyte and platelet transfusions from a single donor in serological window-phase of hepatitis C. Vox Sang 1996; 71: 55-57 [PMID: 8837359]
    • (1996) Vox Sang , vol.71 , pp. 55-57
    • Widell, A.1    Elmud, H.2    Persson, M.H.3    Jonsson, M.4
  • 58
    • 83755183801 scopus 로고    scopus 로고
    • The role of neutralizing antibodies in hepatitis C virus infection
    • PMID: 22049091
    • Edwards VC, Tarr AW, Urbanowicz RA, Ball JK. The role of neutralizing antibodies in hepatitis C virus infection. J Gen Virol 2012; 93: 1-19 [PMID: 22049091]
    • (2012) J Gen Virol , vol.93 , pp. 1-19
    • Edwards, V.C.1    Tarr, A.W.2    Urbanowicz, R.A.3    Ball, J.K.4
  • 60
    • 0028114164 scopus 로고
    • Hepatitis C infection in patients with primary hypogammaglobulinemia after treatment with contaminated immune globulin
    • PMID: 7526215
    • Bjøro K, Frøland SS, Yun Z, Samdal HH, Haaland T. Hepatitis C infection in patients with primary hypogammaglobulinemia after treatment with contaminated immune globulin. N Engl J Med 1994; 331: 1607-1611 [PMID: 7526215]
    • (1994) N Engl J Med , vol.331 , pp. 1607-1611
    • Bjøro, K.1    Frøland, S.S.2    Yun, Z.3    Samdal, H.H.4    Haaland, T.5
  • 63
    • 0035206957 scopus 로고    scopus 로고
    • Outcome of intravenous immunoglobulin-transmitted hepatitis C virus infection in primary immunodeficiency
    • PMID: 11726220
    • Razvi S, Schneider L, Jonas MM, Cunningham-Rundles C. Outcome of intravenous immunoglobulin-transmitted hepatitis C virus infection in primary immunodeficiency. Clin Immunol 2001; 101: 284-288 [PMID: 11726220]
    • (2001) Clin Immunol , vol.101 , pp. 284-288
    • Razvi, S.1    Schneider, L.2    Jonas, M.M.3    Cunningham-Rundles, C.4
  • 64
    • 84868207639 scopus 로고    scopus 로고
    • B cell homeostasis in chronic hepatitis C virusrelated mixed cryoglobulinemia is maintained through naïve B cell apoptosis
    • PMID: 22556016
    • Holz LE, Yoon JC, Raghuraman S, Moir S, Sneller MC, Rehermann B. B cell homeostasis in chronic hepatitis C virusrelated mixed cryoglobulinemia is maintained through naïve B cell apoptosis. Hepatology 2012; 56: 1602-1610 [PMID: 22556016]
    • (2012) Hepatology , vol.56 , pp. 1602-1610
    • Holz, L.E.1    Yoon, J.C.2    Raghuraman, S.3    Moir, S.4    Sneller, M.C.5    Rehermann, B.6
  • 66
    • 68849111675 scopus 로고    scopus 로고
    • Hepatitis C virus versus innate and adaptive immune responses: A tale of coevolution and coexistence
    • PMID: 19587449
    • Rehermann B. Hepatitis C virus versus innate and adaptive immune responses: a tale of coevolution and coexistence. J Clin Invest 2009; 119: 1745-1754 [PMID: 19587449]
    • (2009) J Clin Invest , vol.119 , pp. 1745-1754
    • Rehermann, B.1
  • 67
    • 33645729182 scopus 로고    scopus 로고
    • Immunobiology and pathogenesis of viral hepatitis
    • PMID: 18039107
    • Guidotti LG, Chisari FV. Immunobiology and pathogenesis of viral hepatitis. Annu Rev Pathol 2006; 1: 23-61 [PMID: 18039107]
    • (2006) Annu Rev Pathol , vol.1 , pp. 23-61
    • Guidotti, L.G.1    Chisari, F.V.2
  • 68
    • 0034651580 scopus 로고    scopus 로고
    • Pathogenesis, natural history, treatment, and prevention of hepatitis C
    • PMID: 10681285
    • Liang TJ, Rehermann B, Seeff LB, Hoofnagle JH. Pathogenesis, natural history, treatment, and prevention of hepatitis C. Ann Intern Med 2000; 132: 296-305 [PMID: 10681285]
    • (2000) Ann Intern Med , vol.132 , pp. 296-305
    • Liang, T.J.1    Rehermann, B.2    Seeff, L.B.3    Hoofnagle, J.H.4
  • 69
    • 38849095275 scopus 로고    scopus 로고
    • Spontaneous recovery in acute human hepatitis C virus infection: Functional T-cell thresholds and relative importance of CD4 help
    • PMID: 18045940
    • Smyk-Pearson S, Tester IA, Klarquist J, Palmer BE, Pawlotsky JM, Golden-Mason L, Rosen HR. Spontaneous recovery in acute human hepatitis C virus infection: functional T-cell thresholds and relative importance of CD4 help. J Virol 2008; 82: 1827-1837 [PMID: 18045940]
    • (2008) J Virol , vol.82 , pp. 1827-1837
    • Smyk-Pearson, S.1    Tester, I.A.2    Klarquist, J.3    Palmer, B.E.4    Pawlotsky, J.M.5    Golden-Mason, L.6    Rosen, H.R.7
  • 70
    • 33745876557 scopus 로고    scopus 로고
    • Outcome of acute hepatitis C is related to virus-specific CD4 function and maturation of antiviral memory CD8 responses
    • PMID: 16799989
    • Urbani S, Amadei B, Fisicaro P, Tola D, Orlandini A, Sacchelli L, Mori C, Missale G, Ferrari C. Outcome of acute hepatitis C is related to virus-specific CD4 function and maturation of antiviral memory CD8 responses. Hepatology 2006; 44: 126-139 [PMID: 16799989]
    • (2006) Hepatology , vol.44 , pp. 126-139
    • Urbani, S.1    Amadei, B.2    Fisicaro, P.3    Tola, D.4    Orlandini, A.5    Sacchelli, L.6    Mori, C.7    Missale, G.8    Ferrari, C.9
  • 76
    • 0033429088 scopus 로고    scopus 로고
    • Viral heterogeneity of the hepatitis C virus
    • PMID: 10622561
    • Simmonds P. Viral heterogeneity of the hepatitis C virus. J Hepatol 1999; 31 Suppl 1: 54-60 [PMID: 10622561]
    • (1999) J Hepatol , vol.31 , pp. 54-60
    • Simmonds, P.1
  • 77
    • 79957622306 scopus 로고    scopus 로고
    • Vaccination for hepatitis C virus: Closing in on an evasive target
    • PMID: 21604986
    • Halliday J, Klenerman P, Barnes E. Vaccination for hepatitis C virus: closing in on an evasive target. Expert Rev Vaccines 2011; 10: 659-672 [PMID: 21604986]
    • (2011) Expert Rev Vaccines , vol.10 , pp. 659-672
    • Halliday, J.1    Klenerman, P.2    Barnes, E.3
  • 79
    • 0028968636 scopus 로고
    • Persistent hepatitis C virus infection in a chimpanzee is associated with emergence of a cytotoxic T lymphocyte escape variant
    • PMID: 7708719
    • Weiner A, Erickson AL, Kansopon J, Crawford K, Muchmore E, Hughes AL, Houghton M, Walker CM. Persistent hepatitis C virus infection in a chimpanzee is associated with emergence of a cytotoxic T lymphocyte escape variant. Proc Natl Acad Sci USA 1995; 92: 2755-2759 [PMID: 7708719]
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 2755-2759
    • Weiner, A.1    Erickson, A.L.2    Kansopon, J.3    Crawford, K.4    Muchmore, E.5    Hughes, A.L.6    Houghton, M.7    Walker, C.M.8
  • 80
    • 22344448015 scopus 로고    scopus 로고
    • Mutational escape from CD8+ T cell immunity: HCV evolution, from chimpanzees to man
    • PMID: 15939787
    • Bowen DG, Walker CM. Mutational escape from CD8+ T cell immunity: HCV evolution, from chimpanzees to man. J Exp Med 2005; 201: 1709-1714 [PMID: 15939787]
    • (2005) J Exp Med , vol.201 , pp. 1709-1714
    • Bowen, D.G.1    Walker, C.M.2
  • 82
    • 84859432807 scopus 로고    scopus 로고
    • Failure of innate and adaptive immune responses in controlling hepatitis C virus infection
    • PMID: 22142141
    • Thimme R, Binder M, Bartenschlager R. Failure of innate and adaptive immune responses in controlling hepatitis C virus infection. FEMS Microbiol Rev 2012; 36: 663-683 [PMID: 22142141]
    • (2012) FEMS Microbiol Rev , vol.36 , pp. 663-683
    • Thimme, R.1    Binder, M.2    Bartenschlager, R.3
  • 83
    • 14544280209 scopus 로고    scopus 로고
    • Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF
    • PMID: 15710891
    • Li K, Foy E, Ferreon JC, Nakamura M, Ferreon AC, Ikeda M, Ray SC, Gale M, Lemon SM. Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF. Proc Natl Acad Sci USA 2005; 102: 2992-2997 [PMID: 15710891]
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 2992-2997
    • Li, K.1    Foy, E.2    Ferreon, J.C.3    Nakamura, M.4    Ferreon, A.C.5    Ikeda, M.6    Ray, S.C.7    Gale, M.8    Lemon, S.M.9
  • 84
    • 20144379712 scopus 로고    scopus 로고
    • Molecular determinants of TRIF proteolysis mediated by the hepatitis C virus NS3/4A protease
    • PMID: 15767257
    • Ferreon JC, Ferreon AC, Li K, Lemon SM. Molecular determinants of TRIF proteolysis mediated by the hepatitis C virus NS3/4A protease. J Biol Chem 2005; 280: 20483-20492 [PMID: 15767257]
    • (2005) J Biol Chem , vol.280 , pp. 20483-20492
    • Ferreon, J.C.1    Ferreon, A.C.2    Li, K.3    Lemon, S.M.4
  • 85
    • 27144440476 scopus 로고    scopus 로고
    • Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
    • PMID: 16177806
    • Meylan E, Curran J, Hofmann K, Moradpour D, Binder M, Bartenschlager R, Tschopp J. Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus. Nature 2005; 437: 1167-1172 [PMID: 16177806]
    • (2005) Nature , vol.437 , pp. 1167-1172
    • Meylan, E.1    Curran, J.2    Hofmann, K.3    Moradpour, D.4    Binder, M.5    Bartenschlager, R.6    Tschopp, J.7
  • 87
    • 48249137638 scopus 로고    scopus 로고
    • Altered natural killer cell subset distributions in resolved and persistent hepatitis C virus infection following single source exposure
    • PMID: 18372499
    • Golden-Mason L, Madrigal-Estebas L, McGrath E, Conroy MJ, Ryan EJ, Hegarty JE, O'Farrelly C, Doherty DG. Altered natural killer cell subset distributions in resolved and persistent hepatitis C virus infection following single source exposure. Gut 2008; 57: 1121-1128 [PMID: 18372499]
    • (2008) Gut , vol.57 , pp. 1121-1128
    • Golden-Mason, L.1    Madrigal-Estebas, L.2    McGrath, E.3    Conroy, M.J.4    Ryan, E.J.5    Hegarty, J.E.6    O'Farrelly, C.7    Doherty, D.G.8
  • 89
    • 80054987354 scopus 로고    scopus 로고
    • The hepatitis C virus glycan shield and evasion of the humoral immune response
    • PMID: 22069522
    • Helle F, Duverlie G, Dubuisson J. The hepatitis C virus glycan shield and evasion of the humoral immune response. Viruses 2011; 3: 1909-1932 [PMID: 22069522]
    • (2011) Viruses , vol.3 , pp. 1909-1932
    • Helle, F.1    Duverlie, G.2    Dubuisson, J.3
  • 90
    • 84885060120 scopus 로고    scopus 로고
    • Emerging concepts in immunity to hepatitis C virus infection
    • PMID: 24084744
    • Rosen HR. Emerging concepts in immunity to hepatitis C virus infection. J Clin Invest 2013; 123: 4121-4130 [PMID: 24084744]
    • (2013) J Clin Invest , vol.123 , pp. 4121-4130
    • Rosen, H.R.1
  • 91
    • 0034969251 scopus 로고    scopus 로고
    • Hepatitis C virus nonstructural 5A protein induces interleukin-8, leading to partial inhibition of the interferon-induced antiviral response
    • PMID: 11390611
    • Polyak SJ, Khabar KS, Paschal DM, Ezelle HJ, Duverlie G, Barber GN, Levy DE, Mukaida N, Gretch DR. Hepatitis C virus nonstructural 5A protein induces interleukin-8, leading to partial inhibition of the interferon-induced antiviral response. J Virol 2001; 75: 6095-6106 [PMID: 11390611]
    • (2001) J Virol , vol.75 , pp. 6095-6106
    • Polyak, S.J.1    Khabar, K.S.2    Paschal, D.M.3    Ezelle, H.J.4    Duverlie, G.5    Barber, G.N.6    Levy, D.E.7    Mukaida, N.8    Gretch, D.R.9
  • 92
    • 0037362931 scopus 로고    scopus 로고
    • IFN-alpha antagonistic activity of HCV core protein involves induction of suppressor of cytokine signaling-3
    • PMID: 12551851
    • Bode JG, Ludwig S, Ehrhardt C, Albrecht U, Erhardt A, Schaper F, Heinrich PC, Häussinger D. IFN-alpha antagonistic activity of HCV core protein involves induction of suppressor of cytokine signaling-3. FASEB J 2003; 17: 488-490 [PMID: 12551851]
    • (2003) FASEB J , vol.17 , pp. 488-490
    • Bode, J.G.1    Ludwig, S.2    Ehrhardt, C.3    Albrecht, U.4    Erhardt, A.5    Schaper, F.6    Heinrich, P.C.7    Häussinger, D.8
  • 93
    • 33748488244 scopus 로고    scopus 로고
    • Hepatitis C virus core protein blocks interferon signaling by interaction with the STAT1 SH2 domain
    • PMID: 16940534
    • Lin W, Kim SS, Yeung E, Kamegaya Y, Blackard JT, Kim KA, Holtzman MJ, Chung RT. Hepatitis C virus core protein blocks interferon signaling by interaction with the STAT1 SH2 domain. J Virol 2006; 80: 9226-9235 [PMID: 16940534]
    • (2006) J Virol , vol.80 , pp. 9226-9235
    • Lin, W.1    Kim, S.S.2    Yeung, E.3    Kamegaya, Y.4    Blackard, J.T.5    Kim, K.A.6    Holtzman, M.J.7    Chung, R.T.8
  • 94
    • 84874116578 scopus 로고    scopus 로고
    • Innate immunity and HCV
    • PMID: 23063572
    • Heim MH. Innate immunity and HCV. J Hepatol 2013; 58: 564-574 [PMID: 23063572]
    • (2013) J Hepatol , vol.58 , pp. 564-574
    • Heim, M.H.1
  • 96
    • 4744352571 scopus 로고    scopus 로고
    • Role of NK and NKT cells in the immunopathogenesis of HCV-induced hepatitis
    • PMID: 15218054
    • Ahmad A, Alvarez F. Role of NK and NKT cells in the immunopathogenesis of HCV-induced hepatitis. J Leukoc Biol 2004; 76: 743-759 [PMID: 15218054]
    • (2004) J Leukoc Biol , vol.76 , pp. 743-759
    • Ahmad, A.1    Alvarez, F.2
  • 97
    • 33646255673 scopus 로고    scopus 로고
    • The interaction of natural hepatitis C virus with human scavenger receptor SR-BI/Cla1 is mediated by ApoBcontaining lipoproteins
    • PMID: 16476701
    • Maillard P, Huby T, Andréo U, Moreau M, Chapman J, Budkowska A. The interaction of natural hepatitis C virus with human scavenger receptor SR-BI/Cla1 is mediated by ApoBcontaining lipoproteins. FASEB J 2006; 20: 735-737 [PMID: 16476701]
    • (2006) FASEB J , vol.20 , pp. 735-737
    • Maillard, P.1    Huby, T.2    Andréo, U.3    Moreau, M.4    Chapman, J.5    Budkowska, A.6
  • 98
    • 34547098102 scopus 로고    scopus 로고
    • The neutralizing activity of anti-hepatitis C virus antibodies is modulated by specific glycans on the E2 envelope protein
    • PMID: 17522218
    • Helle F, Goffard A, Morel V, Duverlie G, McKeating J, Keck ZY, Foung S, Penin F, Dubuisson J, Voisset C. The neutralizing activity of anti-hepatitis C virus antibodies is modulated by specific glycans on the E2 envelope protein. J Virol 2007; 81: 8101-8111 [PMID: 17522218]
    • (2007) J Virol , vol.81 , pp. 8101-8111
    • Helle, F.1    Goffard, A.2    Morel, V.3    Duverlie, G.4    McKeating, J.5    Keck, Z.Y.6    Foung, S.7    Penin, F.8    Dubuisson, J.9    Voisset, C.10
  • 100
    • 77955659499 scopus 로고    scopus 로고
    • Depletion of interfering antibodies in chronic hepatitis C patients and vaccinated chimpanzees reveals broad cross-genotype neutralizing activity
    • Zhang P, Zhong L, Struble EB. Depletion of interfering antibodies in chronic hepatitis C patients and vaccinated chimpanzees reveals broad cross-genotype neutralizing activity. J Infect Dis 2010; 202: 862-866 [DOI: 10.1086/655902]
    • (2010) J Infect Dis , vol.202 , pp. 862-866
    • Zhang, P.1    Zhong, L.2    Struble, E.B.3
  • 102
    • 34249787349 scopus 로고    scopus 로고
    • Hepatitis C virus (HCV)-specific CD8+ cells produce transforming growth factor beta that can suppress HCVspecific T-cell responses
    • PMID: 17376924
    • Alatrakchi N, Graham CS, van der Vliet HJ, Sherman KE, Exley MA, Koziel MJ. Hepatitis C virus (HCV)-specific CD8+ cells produce transforming growth factor beta that can suppress HCVspecific T-cell responses. J Virol 2007; 81: 5882-5892 [PMID: 17376924]
    • (2007) J Virol , vol.81 , pp. 5882-5892
    • Alatrakchi, N.1    Graham, C.S.2    Van Der Vliet, H.J.3    Sherman, K.E.4    Exley, M.A.5    Koziel, M.J.6
  • 103
    • 33947421722 scopus 로고    scopus 로고
    • Dysfunction and functional restoration of HCV-specific CD8 responses in chronic hepatitis C virus infection
    • PMID: 17326153
    • Penna A, Pilli M, Zerbini A, Orlandini A, Mezzadri S, Sacchelli L, Missale G, Ferrari C. Dysfunction and functional restoration of HCV-specific CD8 responses in chronic hepatitis C virus infection. Hepatology 2007; 45: 588-601 [PMID: 17326153]
    • (2007) Hepatology , vol.45 , pp. 588-601
    • Penna, A.1    Pilli, M.2    Zerbini, A.3    Orlandini, A.4    Mezzadri, S.5    Sacchelli, L.6    Missale, G.7    Ferrari, C.8
  • 104
    • 85027929950 scopus 로고    scopus 로고
    • Persistent hepatitis C virus (HCV) infection impairs HCV-specific cytotoxic T cell reactivity through Mcl-1/Bim imbalance due to CD127 down-regulation
    • PMID: 23301543
    • Larrubia JR, Lokhande MU, García-Garzón S, Miquel J, González-Praetorius A, Parra-Cid T, Sanz-de-Villalobos E. Persistent hepatitis C virus (HCV) infection impairs HCV-specific cytotoxic T cell reactivity through Mcl-1/Bim imbalance due to CD127 down-regulation. J Viral Hepat 2013; 20: 85-94 [PMID: 23301543]
    • (2013) J Viral Hepat , vol.20 , pp. 85-94
    • Larrubia, J.R.1    Lokhande, M.U.2    García-Garzón, S.3    Miquel, J.4    González-Praetorius, A.5    Parra-Cid, T.6    Sanz-De-Villalobos, E.7
  • 105
    • 0345017746 scopus 로고    scopus 로고
    • Suppression of HCV-specific T cells without differential hierarchy demonstrated ex vivo in persistent HCV infection
    • PMID: 14647055
    • Sugimoto K, Ikeda F, Stadanlick J, Nunes FA, Alter HJ, Chang KM. Suppression of HCV-specific T cells without differential hierarchy demonstrated ex vivo in persistent HCV infection. Hepatology 2003; 38: 1437-1448 [PMID: 14647055]
    • (2003) Hepatology , vol.38 , pp. 1437-1448
    • Sugimoto, K.1    Ikeda, F.2    Stadanlick, J.3    Nunes, F.A.4    Alter, H.J.5    Chang, K.M.6
  • 107
    • 0030671121 scopus 로고    scopus 로고
    • Immunological significance of cytotoxic T lymphocyte epitope variants in patients chronically infected by the hepatitis C virus
    • PMID: 9410918
    • Chang KM, Rehermann B, McHutchison JG, Pasquinelli C, Southwood S, Sette A, Chisari FV. Immunological significance of cytotoxic T lymphocyte epitope variants in patients chronically infected by the hepatitis C virus. J Clin Invest 1997; 100: 2376-2385 [PMID: 9410918]
    • (1997) J Clin Invest , vol.100 , pp. 2376-2385
    • Chang, K.M.1    Rehermann, B.2    McHutchison, J.G.3    Pasquinelli, C.4    Southwood, S.5    Sette, A.6    Chisari, F.V.7
  • 108
    • 22344447485 scopus 로고    scopus 로고
    • Divergent and convergent evolution after a commonsource outbreak of hepatitis C virus
    • PMID: 15939791
    • Ray SC, Fanning L, Wang XH, Netski DM, Kenny-Walsh E, Thomas DL. Divergent and convergent evolution after a commonsource outbreak of hepatitis C virus. J Exp Med 2005; 201: 1753-1759 [PMID: 15939791]
    • (2005) J Exp Med , vol.201 , pp. 1753-1759
    • Ray, S.C.1    Fanning, L.2    Wang, X.H.3    Netski, D.M.4    Kenny-Walsh, E.5    Thomas, D.L.6
  • 109
    • 19944428565 scopus 로고    scopus 로고
    • Schulze zur Wiesch J, Gandhi RT, Chung RT, Bhardwaj N, Klenerman P, Walker BD, Allen TM. CD8 epitope escape and reversion in acute HCV infection
    • PMID: 15611288
    • Timm J, Lauer GM, Kavanagh DG, Sheridan I, Kim AY, Lucas M, Pillay T, Ouchi K, Reyor LL, Schulze zur Wiesch J, Gandhi RT, Chung RT, Bhardwaj N, Klenerman P, Walker BD, Allen TM. CD8 epitope escape and reversion in acute HCV infection. J Exp Med 2004; 200: 1593-1604 [PMID: 15611288]
    • (2004) J Exp Med , vol.200 , pp. 1593-1604
    • Timm, J.1    Lauer, G.M.2    Kavanagh, D.G.3    Sheridan, I.4    Kim, A.Y.5    Lucas, M.6    Pillay, T.7    Ouchi, K.8    Reyor, L.L.9
  • 110
    • 34047172640 scopus 로고    scopus 로고
    • IL-10, T cell exhaustion and viral persistence
    • PMID: 17336072
    • Blackburn SD, Wherry EJ. IL-10, T cell exhaustion and viral persistence. Trends Microbiol 2007; 15: 143-146 [PMID: 17336072]
    • (2007) Trends Microbiol , vol.15 , pp. 143-146
    • Blackburn, S.D.1    Wherry, E.J.2
  • 111
    • 79956077563 scopus 로고    scopus 로고
    • T cell exhaustion
    • PMID: 21739672
    • Wherry EJ. T cell exhaustion. Nat Immunol 2011; 12: 492-499 [PMID: 21739672]
    • (2011) Nat Immunol , vol.12 , pp. 492-499
    • Wherry, E.J.1
  • 113
    • 34548191951 scopus 로고    scopus 로고
    • Upregulation of PD-1 expression on circulating and intrahepatic hepatitis C virus-specific CD8+ T cells associated with reversible immune dysfunction
    • PMID: 17567698
    • Golden-Mason L, Palmer B, Klarquist J, Mengshol JA, Castelblanco N, Rosen HR. Upregulation of PD-1 expression on circulating and intrahepatic hepatitis C virus-specific CD8+ T cells associated with reversible immune dysfunction. J Virol 2007; 81: 9249-9258 [PMID: 17567698]
    • (2007) J Virol , vol.81 , pp. 9249-9258
    • Golden-Mason, L.1    Palmer, B.2    Klarquist, J.3    Mengshol, J.A.4    Castelblanco, N.5    Rosen, H.R.6
  • 116
    • 65549136983 scopus 로고    scopus 로고
    • Mechanisms of foxp3+ T regulatory cell-mediated suppression
    • PMID: 19464986
    • Shevach EM. Mechanisms of foxp3+ T regulatory cell-mediated suppression. Immunity 2009; 30: 636-645 [PMID: 19464986]
    • (2009) Immunity , vol.30 , pp. 636-645
    • Shevach, E.M.1
  • 117
    • 19944370822 scopus 로고    scopus 로고
    • T cells with a CD4+CD25+ regulatory phenotype suppress in vitro proliferation of virus-specific CD8+ T cells during chronic hepatitis C virus infection
    • PMID: 15919940
    • Boettler T, Spangenberg HC, Neumann-Haefelin C, Panther E, Urbani S, Ferrari C, Blum HE, von Weizsäcker F, Thimme R. T cells with a CD4+CD25+ regulatory phenotype suppress in vitro proliferation of virus-specific CD8+ T cells during chronic hepatitis C virus infection. J Virol 2005; 79: 7860-7867 [PMID: 15919940]
    • (2005) J Virol , vol.79 , pp. 7860-7867
    • Boettler, T.1    Spangenberg, H.C.2    Neumann-Haefelin, C.3    Panther, E.4    Urbani, S.5    Ferrari, C.6    Blum, H.E.7    Von Weizsäcker, F.8    Thimme, R.9
  • 118
    • 7044247947 scopus 로고    scopus 로고
    • An immunomodulatory role for CD4(+)CD25(+) regulatory T lymphocytes in hepatitis C virus infection
    • PMID: 15486925
    • Cabrera R, Tu Z, Xu Y, Firpi RJ, Rosen HR, Liu C, Nelson DR. An immunomodulatory role for CD4(+)CD25(+) regulatory T lymphocytes in hepatitis C virus infection. Hepatology 2004; 40: 1062-1071 [PMID: 15486925]
    • (2004) Hepatology , vol.40 , pp. 1062-1071
    • Cabrera, R.1    Tu, Z.2    Xu, Y.3    Firpi, R.J.4    Rosen, H.R.5    Liu, C.6    Nelson, D.R.7
  • 119
    • 19944366276 scopus 로고    scopus 로고
    • Regulatory T cells suppress in vitro proliferation of virus-specific CD8+ T cells during persistent hepatitis C virus infection
    • PMID: 15919939
    • Rushbrook SM, Ward SM, Unitt E, Vowler SL, Lucas M, Klenerman P, Alexander GJ. Regulatory T cells suppress in vitro proliferation of virus-specific CD8+ T cells during persistent hepatitis C virus infection. J Virol 2005; 79: 7852-7859 [PMID: 15919939]
    • (2005) J Virol , vol.79 , pp. 7852-7859
    • Rushbrook, S.M.1    Ward, S.M.2    Unitt, E.3    Vowler, S.L.4    Lucas, M.5    Klenerman, P.6    Alexander, G.J.7
  • 120
    • 33744460201 scopus 로고    scopus 로고
    • Foxp3+CD4+CD25+ T cells control virus-specific memory T cells in chimpanzees that recovered from hepatitis C
    • PMID: 16478885
    • Manigold T, Shin EC, Mizukoshi E, Mihalik K, Murthy KK, Rice CM, Piccirillo CA, Rehermann B. Foxp3+CD4+CD25+ T cells control virus-specific memory T cells in chimpanzees that recovered from hepatitis C. Blood 2006; 107: 4424-4432 [PMID: 16478885]
    • (2006) Blood , vol.107 , pp. 4424-4432
    • Manigold, T.1    Shin, E.C.2    Mizukoshi, E.3    Mihalik, K.4    Murthy, K.K.5    Rice, C.M.6    Piccirillo, C.A.7    Rehermann, B.8
  • 121
    • 0033180064 scopus 로고    scopus 로고
    • Hepatocellular mitochondrial alterations in patients with chronic hepatitis C: Ultrastructural and biochemical findings
    • PMID: 10445550
    • Barbaro G, Di Lorenzo G, Asti A, Ribersani M, Belloni G, Grisorio B, Filice G, Barbarini G. Hepatocellular mitochondrial alterations in patients with chronic hepatitis C: ultrastructural and biochemical findings. Am J Gastroenterol 1999; 94: 2198-2205 [PMID: 10445550]
    • (1999) Am J Gastroenterol , vol.94 , pp. 2198-2205
    • Barbaro, G.1    Di Lorenzo, G.2    Asti, A.3    Ribersani, M.4    Belloni, G.5    Grisorio, B.6    Filice, G.7    Barbarini, G.8
  • 122
    • 0034113670 scopus 로고    scopus 로고
    • Successful interferon therapy reverses enhanced hepatic iron accumulation and lipid peroxidation in chronic hepatitis C
    • PMID: 10763957
    • Kageyama F, Kobayashi Y, Kawasaki T, Toyokuni S, Uchida K, Nakamura H. Successful interferon therapy reverses enhanced hepatic iron accumulation and lipid peroxidation in chronic hepatitis C. Am J Gastroenterol 2000; 95: 1041-1050 [PMID: 10763957]
    • (2000) Am J Gastroenterol , vol.95 , pp. 1041-1050
    • Kageyama, F.1    Kobayashi, Y.2    Kawasaki, T.3    Toyokuni, S.4    Uchida, K.5    Nakamura, H.6
  • 123
    • 0031011220 scopus 로고    scopus 로고
    • In situ detection of lipid peroxidation by-products in chronic liver diseases
    • PMID: 9214462
    • Paradis V, Kollinger M, Fabre M, Holstege A, Poynard T, Bedossa P. In situ detection of lipid peroxidation by-products in chronic liver diseases. Hepatology 1997; 26: 135-142 [PMID: 9214462]
    • (1997) Hepatology , vol.26 , pp. 135-142
    • Paradis, V.1    Kollinger, M.2    Fabre, M.3    Holstege, A.4    Poynard, T.5    Bedossa, P.6
  • 125
    • 80052166468 scopus 로고    scopus 로고
    • Impact of the autophagy machinery on hepatitis C virus infection
    • PMID: 21994783
    • Dreux M, Chisari FV. Impact of the autophagy machinery on hepatitis C virus infection. Viruses 2011; 3: 1342-1357 [PMID: 21994783]
    • (2011) Viruses , vol.3 , pp. 1342-1357
    • Dreux, M.1    Chisari, F.V.2
  • 126
    • 69549135689 scopus 로고    scopus 로고
    • The autophagy machinery is required to initiate hepatitis C virus replication
    • PMID: 19666601
    • Dreux M, Gastaminza P, Wieland SF, Chisari FV. The autophagy machinery is required to initiate hepatitis C virus replication. Proc Natl Acad Sci USA 2009; 106: 14046-14051 [PMID: 19666601]
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 14046-14051
    • Dreux, M.1    Gastaminza, P.2    Wieland, S.F.3    Chisari, F.V.4
  • 127
    • 84875993938 scopus 로고    scopus 로고
    • Hepatitis C virus induces the mitochondrial translocation of Parkin and subsequent mitophagy
    • PMID: 23555273
    • Kim SJ, Syed GH, Siddiqui A. Hepatitis C virus induces the mitochondrial translocation of Parkin and subsequent mitophagy. PLoS Pathog 2013; 9: e1003285 [PMID: 23555273]
    • (2013) PLoS Pathog , vol.9 , pp. e1003285
    • Kim, S.J.1    Syed, G.H.2    Siddiqui, A.3
  • 132
    • 34250634419 scopus 로고    scopus 로고
    • New animal models for hepatitis C viral infection and pathogenesis studies
    • PMID: 17552025
    • Kremsdorf D, Brezillon N. New animal models for hepatitis C viral infection and pathogenesis studies. World J Gastroenterol 2007; 13: 2427-2435 [PMID: 17552025]
    • (2007) World J Gastroenterol , vol.13 , pp. 2427-2435
    • Kremsdorf, D.1    Brezillon, N.2
  • 133
    • 84885335829 scopus 로고    scopus 로고
    • Hepatitis C virus infection and related liver disease: The quest for the best animal model
    • PMID: 23898329
    • Mailly L, Robinet E, Meuleman P, Baumert TF, Zeisel MB. Hepatitis C virus infection and related liver disease: the quest for the best animal model. Front Microbiol 2013; 4: 213 [PMID: 23898329]
    • (2013) Front Microbiol , vol.4 , pp. 213
    • Mailly, L.1    Robinet, E.2    Meuleman, P.3    Baumert, T.F.4    Zeisel, M.B.5
  • 134
    • 0035235411 scopus 로고    scopus 로고
    • The chimpanzee model of hepatitis C virus infections
    • PMID: 11406714
    • Lanford RE, Bigger C, Bassett S, Klimpel G. The chimpanzee model of hepatitis C virus infections. ILAR J 2001; 42: 117-126 [PMID: 11406714]
    • (2001) ILAR J , vol.42 , pp. 117-126
    • Lanford, R.E.1    Bigger, C.2    Bassett, S.3    Klimpel, G.4
  • 135
    • 34548277125 scopus 로고    scopus 로고
    • Efficient infection of tree shrew (Tupaia belangeri) with hepatitis C virus grown in cell culture or from patient plasma
    • PMID: 17698660
    • Xu X, Chen H, Cao X, Ben K. Efficient infection of tree shrew (Tupaia belangeri) with hepatitis C virus grown in cell culture or from patient plasma. J Gen Virol 2007; 88: 2504-2512 [PMID: 17698660]
    • (2007) J Gen Virol , vol.88 , pp. 2504-2512
    • Xu, X.1    Chen, H.2    Cao, X.3    Ben, K.4
  • 138
    • 0037416146 scopus 로고    scopus 로고
    • Infectious hepatitis C virus pseudo-particles containing functional E1-E2 envelope protein complexes
    • PMID: 12615904
    • Bartosch B, Dubuisson J, Cosset FL. Infectious hepatitis C virus pseudo-particles containing functional E1-E2 envelope protein complexes. J Exp Med 2003; 197: 633-642 [PMID: 12615904]
    • (2003) J Exp Med , vol.197 , pp. 633-642
    • Bartosch, B.1    Dubuisson, J.2    Cosset, F.L.3
  • 139
    • 84919382829 scopus 로고    scopus 로고
    • The Humoral Immune Response to HCV: Understanding is Key to Vaccine Development
    • PMID: 25426115
    • Cashman SB, Marsden BD, Dustin LB. The Humoral Immune Response to HCV: Understanding is Key to Vaccine Development. Front Immunol 2014; 5: 550 [PMID: 25426115]
    • (2014) Front Immunol , vol.5 , pp. 550
    • Cashman, S.B.1    Marsden, B.D.2    Dustin, L.B.3
  • 141
    • 33144471074 scopus 로고    scopus 로고
    • Production of infectious genotype 1a hepatitis C virus (Hutchinson strain) in cultured human hepatoma cells
    • PMID: 16461899
    • Yi M, Villanueva RA, Thomas DL, Wakita T, Lemon SM. Production of infectious genotype 1a hepatitis C virus (Hutchinson strain) in cultured human hepatoma cells. Proc Natl Acad Sci USA 2006; 103: 2310-2315 [PMID: 16461899]
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 2310-2315
    • Yi, M.1    Villanueva, R.A.2    Thomas, D.L.3    Wakita, T.4    Lemon, S.M.5
  • 142
    • 84859646587 scopus 로고    scopus 로고
    • Advances in hepatitis C virus vaccines, part two: Advances in hepatitis C virus vaccine formulations and modalities
    • PMID: 22455502
    • Roohvand F, Kossari N. Advances in hepatitis C virus vaccines, part two: advances in hepatitis C virus vaccine formulations and modalities. Expert Opin Ther Pat 2012; 22: 391-415 [PMID: 22455502]
    • (2012) Expert Opin Ther Pat , vol.22 , pp. 391-415
    • Roohvand, F.1    Kossari, N.2
  • 143
    • 72249087933 scopus 로고    scopus 로고
    • Spontaneous control of primary hepatitis C virus infection and immunity against persistent reinfection
    • PMID: 19782080
    • Osburn WO, Fisher BE, Dowd KA, Urban G, Liu L, Ray SC, Thomas DL, Cox AL. Spontaneous control of primary hepatitis C virus infection and immunity against persistent reinfection. Gastroenterology 2010; 138: 315-324 [PMID: 19782080]
    • (2010) Gastroenterology , vol.138 , pp. 315-324
    • Osburn, W.O.1    Fisher, B.E.2    Dowd, K.A.3    Urban, G.4    Liu, L.5    Ray, S.C.6    Thomas, D.L.7    Cox, A.L.8
  • 144
    • 77956168246 scopus 로고    scopus 로고
    • Meta-analysis of hepatitis C virus vaccine efficacy in chimpanzees indicates an importance for structural proteins
    • PMID: 20621699
    • Dahari H, Feinstone SM, Major ME. Meta-analysis of hepatitis C virus vaccine efficacy in chimpanzees indicates an importance for structural proteins. Gastroenterology 2010; 139: 965-974 [PMID: 20621699]
    • (2010) Gastroenterology , vol.139 , pp. 965-974
    • Dahari, H.1    Feinstone, S.M.2    Major, M.E.3
  • 145
    • 34748815771 scopus 로고    scopus 로고
    • Phase i clinical study of a personalized peptide vaccination for patients infected with hepatitis C virus (HCV) 1b who failed to respond to interferon-based therapy
    • PMID: 17845828
    • Yutani S, Yamada A, Yoshida K, Takao Y, Tamura M, Komatsu N, Ide T, Tanaka M, Sata M, Itoh K. Phase I clinical study of a personalized peptide vaccination for patients infected with hepatitis C virus (HCV) 1b who failed to respond to interferon-based therapy. Vaccine 2007; 25: 7429-7435 [PMID: 17845828]
    • (2007) Vaccine , vol.25 , pp. 7429-7435
    • Yutani, S.1    Yamada, A.2    Yoshida, K.3    Takao, Y.4    Tamura, M.5    Komatsu, N.6    Ide, T.7    Tanaka, M.8    Sata, M.9    Itoh, K.10
  • 148
    • 0030761598 scopus 로고    scopus 로고
    • Impaired induction of cytotoxic T lymphocytes by antagonism of a weak agonist borne by a variant hepatitis C virus epitope
    • PMID: 9247592
    • Kaneko T, Moriyama T, Udaka K, Hiroishi K, Kita H, Okamoto H, Yagita H, Okumura K, Imawari M. Impaired induction of cytotoxic T lymphocytes by antagonism of a weak agonist borne by a variant hepatitis C virus epitope. Eur J Immunol 1997; 27: 1782-1787 [PMID: 9247592]
    • (1997) Eur J Immunol , vol.27 , pp. 1782-1787
    • Kaneko, T.1    Moriyama, T.2    Udaka, K.3    Hiroishi, K.4    Kita, H.5    Okamoto, H.6    Yagita, H.7    Okumura, K.8    Imawari, M.9
  • 149
    • 33646144429 scopus 로고    scopus 로고
    • Immunogenicity and safety of a novel therapeutic hepatitis C virus (HCV) peptide vaccine: A randomized, placebo controlled trial for dose optimization in 128 healthy subjects
    • PMID: 16581161
    • Firbas C, Jilma B, Tauber E, Buerger V, Jelovcan S, Lingnau K, Buschle M, Frisch J, Klade CS. Immunogenicity and safety of a novel therapeutic hepatitis C virus (HCV) peptide vaccine: a randomized, placebo controlled trial for dose optimization in 128 healthy subjects. Vaccine 2006; 24: 4343-4353 [PMID: 16581161]
    • (2006) Vaccine , vol.24 , pp. 4343-4353
    • Firbas, C.1    Jilma, B.2    Tauber, E.3    Buerger, V.4    Jelovcan, S.5    Lingnau, K.6    Buschle, M.7    Frisch, J.8    Klade, C.S.9
  • 150
    • 77549085401 scopus 로고    scopus 로고
    • Immunogenicity and safety of different injection routes and schedules of IC41, a Hepatitis C virus (HCV) peptide vaccine
    • PMID: 20060945
    • Firbas C, Boehm T, Buerger V, Schuller E, Sabarth N, Jilma B, Klade CS. Immunogenicity and safety of different injection routes and schedules of IC41, a Hepatitis C virus (HCV) peptide vaccine. Vaccine 2010; 28: 2397-2407 [PMID: 20060945]
    • (2010) Vaccine , vol.28 , pp. 2397-2407
    • Firbas, C.1    Boehm, T.2    Buerger, V.3    Schuller, E.4    Sabarth, N.5    Jilma, B.6    Klade, C.S.7
  • 151
    • 84859436059 scopus 로고    scopus 로고
    • Sustained viral load reduction in treatment-naive HCV genotype 1 infected patients after therapeutic peptide vaccination
    • PMID: 22401867
    • Klade CS, Schuller E, Boehm T, von Gabain A, Manns MP. Sustained viral load reduction in treatment-naive HCV genotype 1 infected patients after therapeutic peptide vaccination. Vaccine 2012; 30: 2943-2950 [PMID: 22401867]
    • (2012) Vaccine , vol.30 , pp. 2943-2950
    • Klade, C.S.1    Schuller, E.2    Boehm, T.3    Von Gabain, A.4    Manns, M.P.5
  • 152
    • 70349596123 scopus 로고    scopus 로고
    • Phase i clinical study of a peptide vaccination for hepatitis C virus-infected patients with different human leukocyte antigen-class I-A alleles
    • PMID: 19604246
    • Yutani S, Komatsu N, Shichijo S, Yoshida K, Takedatsu H, Itou M, Kuromatu R, Ide T, Tanaka M, Sata M, Yamada A, Itoh K. Phase I clinical study of a peptide vaccination for hepatitis C virus-infected patients with different human leukocyte antigen-class I-A alleles. Cancer Sci 2009; 100: 1935-1942 [PMID: 19604246]
    • (2009) Cancer Sci , vol.100 , pp. 1935-1942
    • Yutani, S.1    Komatsu, N.2    Shichijo, S.3    Yoshida, K.4    Takedatsu, H.5    Itou, M.6    Kuromatu, R.7    Ide, T.8    Tanaka, M.9    Sata, M.10    Yamada, A.11    Itoh, K.12
  • 154
    • 23944452579 scopus 로고    scopus 로고
    • Prospects for a vaccine against the hepatitis C virus
    • PMID: 16107836
    • Houghton M, Abrignani S. Prospects for a vaccine against the hepatitis C virus. Nature 2005; 436: 961-966 [PMID: 16107836]
    • (2005) Nature , vol.436 , pp. 961-966
    • Houghton, M.1    Abrignani, S.2
  • 155
    • 1242293129 scopus 로고    scopus 로고
    • Immunization of chimpanzees with an envelope protein-based vaccine enhances specific humoral and cellular immune responses that delay hepatitis C virus infection
    • PMID: 15161076
    • Puig M, Major ME, Mihalik K, Feinstone SM. Immunization of chimpanzees with an envelope protein-based vaccine enhances specific humoral and cellular immune responses that delay hepatitis C virus infection. Vaccine 2004; 22: 991-1000 [PMID: 15161076]
    • (2004) Vaccine , vol.22 , pp. 991-1000
    • Puig, M.1    Major, M.E.2    Mihalik, K.3    Feinstone, S.M.4
  • 158
    • 33748951719 scopus 로고    scopus 로고
    • CD4+ immune escape and subsequent T-cell failure following chimpanzee immunization against hepatitis C virus
    • PMID: 16941702
    • Puig M, Mihalik K, Tilton JC, Williams O, Merchlinsky M, Connors M, Feinstone SM, Major ME. CD4+ immune escape and subsequent T-cell failure following chimpanzee immunization against hepatitis C virus. Hepatology 2006; 44: 736-745 [PMID: 16941702]
    • (2006) Hepatology , vol.44 , pp. 736-745
    • Puig, M.1    Mihalik, K.2    Tilton, J.C.3    Williams, O.4    Merchlinsky, M.5    Connors, M.6    Feinstone, S.M.7    Major, M.E.8
  • 160
    • 3843137346 scopus 로고    scopus 로고
    • A candidate vaccine based on the hepatitis C E1 protein: Tolerability and immunogenicity in healthy volunteers
    • PMID: 15297058
    • Leroux-Roels G, Depla E, Hulstaert F, Tobback L, Dincq S, Desmet J, Desombere I, Maertens G. A candidate vaccine based on the hepatitis C E1 protein: tolerability and immunogenicity in healthy volunteers. Vaccine 2004; 22: 3080-3086 [PMID: 15297058]
    • (2004) Vaccine , vol.22 , pp. 3080-3086
    • Leroux-Roels, G.1    Depla, E.2    Hulstaert, F.3    Tobback, L.4    Dincq, S.5    Desmet, J.6    Desombere, I.7    Maertens, G.8
  • 166
    • 84947444806 scopus 로고    scopus 로고
    • Recent advances in clinical trials of HCV vaccines
    • Luo Y, Jiang L, Mao Z. Recent Advances in Clinical Trials of HCV Vaccines. J Applied Virol 2014; 3: 10-24
    • (2014) J Applied Virol , vol.3 , pp. 10-24
    • Luo, Y.1    Jiang, L.2    Mao, Z.3
  • 167
    • 68649126284 scopus 로고    scopus 로고
    • GI-5005, a yeast vector vaccine expressing an NS3-core fusion protein for chronic HCV infection
    • PMID: 19649991
    • Habersetzer F, Baumert TF, Stoll-Keller F. GI-5005, a yeast vector vaccine expressing an NS3-core fusion protein for chronic HCV infection. Curr Opin Mol Ther 2009; 11: 456-462 [PMID: 19649991]
    • (2009) Curr Opin Mol Ther , vol.11 , pp. 456-462
    • Habersetzer, F.1    Baumert, T.F.2    Stoll-Keller, F.3
  • 168
    • 80051936839 scopus 로고    scopus 로고
    • GI-5005 therapeutic vaccine plus pegIFN/ribavirin improves sustained virologic response versus pegIFN/ribavirin in prior non-responders with genotype 1 chronic HCV infection
    • Pockros P, Jacobson I, Boyer TD. GI-5005 therapeutic vaccine plus pegIFN/ribavirin improves sustained virologic response versus pegIFN/ribavirin in prior non-responders with genotype 1 chronic HCV infection. Hepatology 2010; 52: 107A
    • (2010) Hepatology , vol.52 , pp. 107A
    • Pockros, P.1    Jacobson, I.2    Boyer, T.D.3
  • 169
    • 0035051928 scopus 로고    scopus 로고
    • West Nile virus recombinant DNA vaccine protects mouse and horse from virus challenge and expresses in vitro a noninfectious recombinant antigen that can be used in enzyme-linked immunosorbent assays
    • PMID: 11287553
    • Davis BS, Chang GJ, Cropp B, Roehrig JT, Martin DA, Mitchell CJ, Bowen R, Bunning ML. West Nile virus recombinant DNA vaccine protects mouse and horse from virus challenge and expresses in vitro a noninfectious recombinant antigen that can be used in enzyme-linked immunosorbent assays. J Virol 2001; 75: 4040-4047 [PMID: 11287553]
    • (2001) J Virol , vol.75 , pp. 4040-4047
    • Davis, B.S.1    Chang, G.J.2    Cropp, B.3    Roehrig, J.T.4    Martin, D.A.5    Mitchell, C.J.6    Bowen, R.7    Bunning, M.L.8
  • 173
    • 0027713245 scopus 로고
    • DNA inoculation induces neutralizing immune responses against human immunodeficiency virus type 1 in mice and nonhuman primates
    • PMID: 8216851
    • Wang B, Boyer J, Srikantan V, Coney L, Carrano R, Phan C, Merva M, Dang K, Agadjanan M, Gilbert L. DNA inoculation induces neutralizing immune responses against human immunodeficiency virus type 1 in mice and nonhuman primates. DNA Cell Biol 1993; 12: 799-805 [PMID: 8216851]
    • (1993) DNA Cell Biol , vol.12 , pp. 799-805
    • Wang, B.1    Boyer, J.2    Srikantan, V.3    Coney, L.4    Carrano, R.5    Phan, C.6    Merva, M.7    Dang, K.8    Agadjanan, M.9    Gilbert, L.10
  • 174
    • 0027283418 scopus 로고
    • Direct gene transfer into skeletal muscle in vivo: Factors affecting efficiency of transfer and stability of expression
    • PMID: 8494924
    • Davis HL, Whalen RG, Demeneix BA. Direct gene transfer into skeletal muscle in vivo: factors affecting efficiency of transfer and stability of expression. Hum Gene Ther 1993; 4: 151-159 [PMID: 8494924]
    • (1993) Hum Gene Ther , vol.4 , pp. 151-159
    • Davis, H.L.1    Whalen, R.G.2    Demeneix, B.A.3
  • 177
    • 28844440938 scopus 로고    scopus 로고
    • In vivo clearance of hepatitis C virus nonstructural 3/4A-expressing hepatocytes by DNA vaccine-primed cytotoxic T lymphocytes
    • PMID: 16288375
    • Ahlen G, Nystrom J, Pult I, Frelin L, Hultgren C, Sallberg M. In vivo clearance of hepatitis C virus nonstructural 3/4A-expressing hepatocytes by DNA vaccine-primed cytotoxic T lymphocytes. J Infect Dis 2005; 192: 2112-2116 [PMID: 16288375]
    • (2005) J Infect Dis , vol.192 , pp. 2112-2116
    • Ahlen, G.1    Nystrom, J.2    Pult, I.3    Frelin, L.4    Hultgren, C.5    Sallberg, M.6
  • 178
    • 1842581995 scopus 로고    scopus 로고
    • Codon optimization and mRNA amplification effectively enhances the immunogenicity of the hepatitis C virus nonstructural 3/4A gene
    • PMID: 14999224
    • Frelin L, Ahlén G, Alheim M, Weiland O, Barnfield C, Liljeström P, Sällberg M. Codon optimization and mRNA amplification effectively enhances the immunogenicity of the hepatitis C virus nonstructural 3/4A gene. Gene Ther 2004; 11: 522-533 [PMID: 14999224]
    • (2004) Gene Ther , vol.11 , pp. 522-533
    • Frelin, L.1    Ahlén, G.2    Alheim, M.3    Weiland, O.4    Barnfield, C.5    Liljeström, P.6    Sällberg, M.7
  • 179
    • 67650558335 scopus 로고    scopus 로고
    • A first clinical trial of therapeutic vaccination using naked DNA delivered by in vivo electroporation shows antiviral effects in patients with chronic hepatitis C
    • Sallberg MM, Frelin L, Diepolder H. A first clinical trial of therapeutic vaccination using naked DNA delivered by in vivo electroporation shows antiviral effects in patients with chronic hepatitis C. J Hepatol 2009; 50: S18-S19
    • (2009) J Hepatol , vol.50 , pp. S18-S19
    • Sallberg, M.M.1    Frelin, L.2    Diepolder, H.3
  • 180
    • 23944485662 scopus 로고    scopus 로고
    • Evasion of intracellular host defence by hepatitis C virus
    • PMID: 16107833
    • Gale M, Foy EM. Evasion of intracellular host defence by hepatitis C virus. Nature 2005; 436: 939-945 [PMID: 16107833]
    • (2005) Nature , vol.436 , pp. 939-945
    • Gale, M.1    Foy, E.M.2
  • 182
    • 33748741785 scopus 로고    scopus 로고
    • Hepatitis C virus NS2 and NS3/4A proteins are potent inhibitors of host cell cytokine/chemokine gene expression
    • PMID: 16945160
    • Kaukinen P, Sillanpää M, Kotenko S, Lin R, Hiscott J, Melén K, Julkunen I. Hepatitis C virus NS2 and NS3/4A proteins are potent inhibitors of host cell cytokine/chemokine gene expression. Virol J 2006; 3: 66 [PMID: 16945160]
    • (2006) Virol J , vol.3 , pp. 66
    • Kaukinen, P.1    Sillanpää, M.2    Kotenko, S.3    Lin, R.4    Hiscott, J.5    Melén, K.6    Julkunen, I.7
  • 184
    • 84879169584 scopus 로고    scopus 로고
    • Perturbations of RNA helicases in cancer
    • PMID: 23658027
    • Robert F, Pelletier J. Perturbations of RNA helicases in cancer. Wiley Interdiscip Rev RNA 2013; 4: 333-349 [PMID: 23658027]
    • (2013) Wiley Interdiscip Rev RNA , vol.4 , pp. 333-349
    • Robert, F.1    Pelletier, J.2
  • 185
    • 84902436687 scopus 로고    scopus 로고
    • Induction of cell-mediated immune responses in mice by DNA vaccines that express hepatitis C virus NS3 mutants lacking serine protease and NTPase/RNA helicase activities
    • PMID: 24901478
    • Ratnoglik SL, Jiang DP, Aoki C, Sudarmono P, Shoji I, Deng L, Hotta H. Induction of cell-mediated immune responses in mice by DNA vaccines that express hepatitis C virus NS3 mutants lacking serine protease and NTPase/RNA helicase activities. PLoS One 2014; 9: e98877 [PMID: 24901478]
    • (2014) PLoS One , vol.9 , pp. e98877
    • Ratnoglik, S.L.1    Jiang, D.P.2    Aoki, C.3    Sudarmono, P.4    Shoji, I.5    Deng, L.6    Hotta, H.7
  • 186
    • 33847218598 scopus 로고    scopus 로고
    • Vaccine delivery methods using viral vectors
    • PMID: 17274663
    • Bråve A, Ljungberg K, Wahren B, Liu MA. Vaccine delivery methods using viral vectors. Mol Pharm 2007; 4: 18-32 [PMID: 17274663]
    • (2007) Mol Pharm , vol.4 , pp. 18-32
    • Bråve, A.1    Ljungberg, K.2    Wahren, B.3    Liu, M.A.4
  • 189
    • 4644318756 scopus 로고    scopus 로고
    • Adenoviruses as vaccine vectors
    • PMID: 15451446
    • Tatsis N, Ertl HC. Adenoviruses as vaccine vectors. Mol Ther 2004; 10: 616-629 [PMID: 15451446]
    • (2004) Mol Ther , vol.10 , pp. 616-629
    • Tatsis, N.1    Ertl, H.C.2
  • 198
    • 33745223435 scopus 로고    scopus 로고
    • Vaccination of colorectal cancer patients with modified vaccinia Ankara delivering the tumor antigen 5T4 (TroVax) induces immune responses which correlate with disease control: A phase I/II trial
    • PMID: 16740766
    • Harrop R, Connolly N, Redchenko I, Valle J, Saunders M, Ryan MG, Myers KA, Drury N, Kingsman SM, Hawkins RE, Carroll MW. Vaccination of colorectal cancer patients with modified vaccinia Ankara delivering the tumor antigen 5T4 (TroVax) induces immune responses which correlate with disease control: a phase I/II trial. Clin Cancer Res 2006; 12: 3416-3424 [PMID: 16740766]
    • (2006) Clin Cancer Res , vol.12 , pp. 3416-3424
    • Harrop, R.1    Connolly, N.2    Redchenko, I.3    Valle, J.4    Saunders, M.5    Ryan, M.G.6    Myers, K.A.7    Drury, N.8    Kingsman Hawkins, S.M.R.E.9    Carroll, M.W.10
  • 199
    • 0018246525 scopus 로고
    • The smallpox vaccination strain MVA: Marker genetic structure experience gained with the parenteral vaccination and behavior in organisms with a debilitated defence mechanism (author's transl)
    • PMID: 219640
    • Mayr A, Stickl H, Müller HK, Danner K, Singer H. [The smallpox vaccination strain MVA: marker, genetic structure, experience gained with the parenteral vaccination and behavior in organisms with a debilitated defence mechanism (author's transl)]. Zentralbl Bakteriol B 1978; 167: 375-390 [PMID: 219640]
    • (1978) Zentralbl Bakteriol B , vol.167 , pp. 375-390
    • Mayr, A.1    Stickl, H.2    Müller, H.K.3    Danner, K.4    Singer, H.5
  • 200
    • 0026442276 scopus 로고
    • Nonreplicating vaccinia vector efficiently expresses recombinant genes
    • PMID: 1438287
    • Sutter G, Moss B. Nonreplicating vaccinia vector efficiently expresses recombinant genes. Proc Natl Acad Sci USA 1992; 89: 10847-10851 [PMID: 1438287]
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 10847-10851
    • Sutter, G.1    Moss, B.2
  • 202
    • 34748832365 scopus 로고    scopus 로고
    • An accelerated vaccine schedule with a poly-antigenic hepatitis C virus MVA-based candidate vaccine induces potent, long lasting and in vivo cross-reactive T cell responses
    • PMID: 17875349
    • Fournillier A, Gerossier E, Evlashev A, Schmitt D, Simon B, Chatel L, Martin P, Silvestre N, Balloul JM, Barry R, Inchauspé G. An accelerated vaccine schedule with a poly-antigenic hepatitis C virus MVA-based candidate vaccine induces potent, long lasting and in vivo cross-reactive T cell responses. Vaccine 2007; 25: 7339-7353 [PMID: 17875349]
    • (2007) Vaccine , vol.25 , pp. 7339-7353
    • Fournillier, A.1    Gerossier, E.2    Evlashev, A.3    Schmitt, D.4    Simon, B.5    Chatel, L.6    Martin, P.7    Silvestre, N.8    Balloul, J.M.9    Barry, R.10    Inchauspé, G.11
  • 204
    • 0037213842 scopus 로고    scopus 로고
    • DNA immunization with hepatitis C virus (HCV) polycistronic genes or immunization by HCV DNA priming-recombinant canarypox virus boosting induces immune responses and protection from recombinant HCV-vaccinia virus infection in HLA-A2.1-transgenic mice
    • PMID: 12477843
    • Pancholi P, Perkus M, Tricoche N, Liu Q, Prince AM. DNA immunization with hepatitis C virus (HCV) polycistronic genes or immunization by HCV DNA priming-recombinant canarypox virus boosting induces immune responses and protection from recombinant HCV-vaccinia virus infection in HLA-A2.1-transgenic mice. J Virol 2003; 77: 382-390 [PMID: 12477843]
    • (2003) J Virol , vol.77 , pp. 382-390
    • Pancholi, P.1    Perkus, M.2    Tricoche, N.3    Liu, Q.4    Prince, A.M.5
  • 205
    • 0033914296 scopus 로고    scopus 로고
    • DNA prime-canarypox boost with polycistronic hepatitis C virus (HCV) genes generates potent immune responses to HCV structural and nonstructural proteins
    • PMID: 10882577
    • Pancholi P, Liu Q, Tricoche N, Zhang P, Perkus ME, Prince AM. DNA prime-canarypox boost with polycistronic hepatitis C virus (HCV) genes generates potent immune responses to HCV structural and nonstructural proteins. J Infect Dis 2000; 182: 18-27 [PMID: 10882577]
    • (2000) J Infect Dis , vol.182 , pp. 18-27
    • Pancholi, P.1    Liu, Q.2    Tricoche, N.3    Zhang, P.4    Perkus, M.E.5    Prince, A.M.6
  • 206
    • 0024307665 scopus 로고
    • Cloning and expression of foreign genes in vaccinia virus, using a host range selection system
    • PMID: 2547999
    • Perkus ME, Limbach K, Paoletti E. Cloning and expression of foreign genes in vaccinia virus, using a host range selection system. J Virol 1989; 63: 3829-3836 [PMID: 2547999]
    • (1989) J Virol , vol.63 , pp. 3829-3836
    • Perkus, M.E.1    Limbach, K.2    Paoletti, E.3
  • 207
    • 55249088800 scopus 로고    scopus 로고
    • Evidence for protection against chronic hepatitis C virus infection in chimpanzees by immunization with replicating recombinant vaccinia virus
    • PMID: 18753204
    • Youn JW, Hu YW, Tricoche N, Pfahler W, Shata MT, Dreux M, Cosset FL, Folgori A, Lee DH, Brotman B, Prince AM. Evidence for protection against chronic hepatitis C virus infection in chimpanzees by immunization with replicating recombinant vaccinia virus. J Virol 2008; 82: 10896-10905 [PMID: 18753204]
    • (2008) J Virol , vol.82 , pp. 10896-10905
    • Youn, J.W.1    Hu, Y.W.2    Tricoche, N.3    Pfahler, W.4    Shata, M.T.5    Dreux, M.6    Cosset, F.L.7    Folgori, A.8    Lee, D.H.9    Brotman, B.10    Prince, A.M.11
  • 208
    • 0036293243 scopus 로고    scopus 로고
    • Global control of hepatitis B virus infection
    • PMID: 12127351
    • Kao JH, Chen DS. Global control of hepatitis B virus infection. Lancet Infect Dis 2002; 2: 395-403 [PMID: 12127351]
    • (2002) Lancet Infect Dis , vol.2 , pp. 395-403
    • Kao, J.H.1    Chen, D.S.2
  • 211
    • 0031977996 scopus 로고    scopus 로고
    • Hepatitis C virus structural proteins assemble into viruslike particles in insect cells
    • PMID: 9557666
    • Baumert TF, Ito S, Wong DT, Liang TJ. Hepatitis C virus structural proteins assemble into viruslike particles in insect cells. J Virol 1998; 72: 3827-3836 [PMID: 9557666]
    • (1998) J Virol , vol.72 , pp. 3827-3836
    • Baumert, T.F.1    Ito, S.2    Wong, D.T.3    Liang, T.J.4
  • 213
    • 0037974714 scopus 로고    scopus 로고
    • Immunization with hepatitis C virus-like particles protects mice from recombinant hepatitis C virus-vaccinia infection
    • PMID: 12748380
    • Murata K, Lechmann M, Qiao M, Gunji T, Alter HJ, Liang TJ. Immunization with hepatitis C virus-like particles protects mice from recombinant hepatitis C virus-vaccinia infection. Proc Natl Acad Sci USA 2003; 100: 6753-6758 [PMID: 12748380]
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 6753-6758
    • Murata, K.1    Lechmann, M.2    Qiao, M.3    Gunji, T.4    Alter, H.J.5    Liang, T.J.6
  • 214
    • 2942643933 scopus 로고    scopus 로고
    • Immunization with hepatitis C virus-like particles induces humoral and cellular immune responses in nonhuman primates
    • PMID: 15194776
    • Jeong SH, Qiao M, Nascimbeni M, Hu Z, Rehermann B, Murthy K, Liang TJ. Immunization with hepatitis C virus-like particles induces humoral and cellular immune responses in nonhuman primates. J Virol 2004; 78: 6995-7003 [PMID: 15194776]
    • (2004) J Virol , vol.78 , pp. 6995-7003
    • Jeong, S.H.1    Qiao, M.2    Nascimbeni, M.3    Hu, Z.4    Rehermann, B.5    Murthy, K.6    Liang, T.J.7
  • 217
    • 0034766336 scopus 로고    scopus 로고
    • Oral immunization with HCV-NS3-transformed Salmonella: Induction of HCV-specific CTL in a transgenic mouse model
    • PMID: 11677208
    • Wedemeyer H, Gagneten S, Davis A, Bartenschlager R, Feinstone S, Rehermann B. Oral immunization with HCV-NS3-transformed Salmonella: induction of HCV-specific CTL in a transgenic mouse model. Gastroenterology 2001; 121: 1158-1166 [PMID: 11677208]
    • (2001) Gastroenterology , vol.121 , pp. 1158-1166
    • Wedemeyer, H.1    Gagneten, S.2    Davis, A.3    Bartenschlager, R.4    Feinstone, S.5    Rehermann, B.6
  • 218
    • 79955087105 scopus 로고    scopus 로고
    • Oral immunization with attenuated Salmonella carrying a co-expression plasmid encoding the core and E2 proteins of hepatitis C virus capable of inducing cellular immune responses and neutralizing antibodies in mice
    • PMID: 21396407
    • Cao J, Chen Z, Ren Y, Luo Y, Cao M, Lu W, Zhao P, Qi Z. Oral immunization with attenuated Salmonella carrying a co-expression plasmid encoding the core and E2 proteins of hepatitis C virus capable of inducing cellular immune responses and neutralizing antibodies in mice. Vaccine 2011; 29: 3714-3723 [PMID: 21396407]
    • (2011) Vaccine , vol.29 , pp. 3714-3723
    • Cao, J.1    Chen, Z.2    Ren, Y.3    Luo, Y.4    Cao, M.5    Lu, W.6    Zhao, P.7    Qi, Z.8
  • 219
    • 43149083669 scopus 로고    scopus 로고
    • Open-label trial of therapeutic immunization with oral V-5 Immunitor (V5) vaccine in patients with chronic hepatitis C
    • PMID: 18455842
    • Batdelger D, Dandii D, Jirathitikal V, Bourinbaiar AS. Open-label trial of therapeutic immunization with oral V-5 Immunitor (V5) vaccine in patients with chronic hepatitis C. Vaccine 2008; 26: 2733-2737 [PMID: 18455842]
    • (2008) Vaccine , vol.26 , pp. 2733-2737
    • Batdelger, D.1    Dandii, D.2    Jirathitikal, V.3    Bourinbaiar, A.S.4
  • 220
    • 0034531322 scopus 로고    scopus 로고
    • Development of a plant-derived subunit vaccine candidate against hepatitis C virus
    • PMID: 11205105
    • Nemchinov LG, Liang TJ, Rifaat MM, Mazyad HM, Hadidi A, Keith JM. Development of a plant-derived subunit vaccine candidate against hepatitis C virus. Arch Virol 2000; 145: 2557-2573 [PMID: 11205105]
    • (2000) Arch Virol , vol.145 , pp. 2557-2573
    • Nemchinov, L.G.1    Liang, T.J.2    Rifaat, M.M.3    Mazyad, H.M.4    Hadidi, A.5    Keith, J.M.6
  • 221
    • 77950968711 scopus 로고    scopus 로고
    • In vitro stability of Cucumber mosaic virus nanoparticles carrying a Hepatitis C virus-derived epitope under simulated gastrointestinal conditions and in vivo efficacy of an edible vaccine
    • PMID: 20132840
    • Nuzzaci M, Vitti A, Condelli V, Lanorte MT, Tortorella C, Boscia D, Piazzolla P, Piazzolla G. In vitro stability of Cucumber mosaic virus nanoparticles carrying a Hepatitis C virus-derived epitope under simulated gastrointestinal conditions and in vivo efficacy of an edible vaccine. J Virol Methods 2010; 165: 211-215 [PMID: 20132840]
    • (2010) J Virol Methods , vol.165 , pp. 211-215
    • Nuzzaci, M.1    Vitti, A.2    Condelli, V.3    Lanorte, M.T.4    Tortorella, C.5    Boscia, D.6    Piazzolla, P.7    Piazzolla, G.8
  • 222
    • 67349209526 scopus 로고    scopus 로고
    • Chimeric hepatitis B and C viruses envelope proteins can form subviral particles: Implications for the design of new vaccine strategies
    • PMID: 19356608
    • Patient R, Hourioux C, Vaudin P, Pagès JC, Roingeard P. Chimeric hepatitis B and C viruses envelope proteins can form subviral particles: implications for the design of new vaccine strategies. N Biotechnol 2009; 25: 226-234 [PMID: 19356608]
    • (2009) N Biotechnol , vol.25 , pp. 226-234
    • Patient, R.1    Hourioux, C.2    Vaudin, P.3    Pagès, J.C.4    Roingeard, P.5
  • 223
    • 0032944906 scopus 로고    scopus 로고
    • Hepatitis C virus core protein fused to hepatitis B virus core antigen for serological diagnosis of both hepatitis C and hepatitis B infections by ELISA
    • PMID: 9892392
    • Wu CL, Leu TS, Chang TT, Shiau AL. Hepatitis C virus core protein fused to hepatitis B virus core antigen for serological diagnosis of both hepatitis C and hepatitis B infections by ELISA. J Med Virol 1999; 57: 104-110 [PMID: 9892392]
    • (1999) J Med Virol , vol.57 , pp. 104-110
    • Wu, C.L.1    Leu, T.S.2    Chang, T.T.3    Shiau, A.L.4
  • 226
    • 84876114944 scopus 로고    scopus 로고
    • Chimeric hepatitis B virus/hepatitis C virus envelope proteins elicit broadly neutralizing antibodies and constitute a potential bivalent prophylactic vaccine
    • PMID: 23150224
    • Beaumont E, Patient R, Hourioux C, Dimier-Poisson I, Roingeard P. Chimeric hepatitis B virus/hepatitis C virus envelope proteins elicit broadly neutralizing antibodies and constitute a potential bivalent prophylactic vaccine. Hepatology 2013; 57: 1303-1313 [PMID: 23150224]
    • (2013) Hepatology , vol.57 , pp. 1303-1313
    • Beaumont, E.1    Patient, R.2    Hourioux, C.3    Dimier-Poisson, I.4    Roingeard, P.5
  • 227
    • 0033848911 scopus 로고    scopus 로고
    • Vaccination of chimpanzees with plasmid DNA encoding the hepatitis C virus (HCV) envelope E2 protein modified the infection after challenge with homologous monoclonal HCV
    • PMID: 10960458
    • Forns X, Payette PJ, Ma X, Satterfield W, Eder G, Mushahwar IK, Govindarajan S, Davis HL, Emerson SU, Purcell RH, Bukh J. Vaccination of chimpanzees with plasmid DNA encoding the hepatitis C virus (HCV) envelope E2 protein modified the infection after challenge with homologous monoclonal HCV. Hepatology 2000; 32: 618-625 [PMID: 10960458]
    • (2000) Hepatology , vol.32 , pp. 618-625
    • Forns, X.1    Payette, P.J.2    Ma, X.3    Satterfield, W.4    Eder, G.5    Mushahwar, I.K.6    Govindarajan, S.7    Davis, H.L.8    Emerson, S.U.9    Purcell, R.H.10    Bukh, J.11


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.