PD-1, PD-L1 and PD-L2 gene expression on t-cells and natural killer cells declines in conjunction with a reduction in PD-1 protein during the intensive phase of tuberculosis treatment

PLoS ONE

Volumn 10, Issue 9, 2015, Pages

  Hassan, Syeda S ^a   Akram, Muhammad ^b   King, Elizabeth C ^a   Dockrell, Hazel M ^a   Cliff, Jacqueline M ^a  

^a LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^b Gulab Devi Hospital   (Pakistan)

Author keywords

[No Author keywords available]

Indexed keywords

GRANZYME B; PROGRAMMED DEATH 1 LIGAND 1; PROGRAMMED DEATH 1 LIGAND 2; PROGRAMMED DEATH 1 RECEPTOR; TUBERCULOSTATIC AGENT;

ADULT; ANTIBIOTIC THERAPY; AREA UNDER THE CURVE; CD3+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL SURFACE; CELLULAR DISTRIBUTION; CLINICAL ARTICLE; COMPARATIVE STUDY; CONFERENCE PAPER; CONTROLLED STUDY; DISEASE ASSOCIATION; DOWN REGULATION; EX VIVO STUDY; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOMODULATION; IMMUNOREGULATION; LATENT TUBERCULOSIS; LIGAND BINDING; MALE; MOLECULAR DYNAMICS; NATURAL KILLER CELL; OUTCOME ASSESSMENT; PERIPHERAL BLOOD MONONUCLEAR CELL; PROTEIN EXPRESSION; RECEIVER OPERATING CHARACTERISTIC; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; T LYMPHOCYTE; TUBERCULOSIS TREATMENT INTENSIVE PHASE; AGED; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; IMMUNOPHENOTYPING; LYMPHOCYTE COUNT; METABOLISM; MIDDLE AGED; MYCOBACTERIUM TUBERCULOSIS; T LYMPHOCYTE SUBPOPULATION; TUBERCULOSIS; YOUNG ADULT;

ADULT; AGED; ANTIGENS, CD274; ANTITUBERCULAR AGENTS; DOWN-REGULATION; FEMALE; GENE EXPRESSION REGULATION; HUMANS; IMMUNOPHENOTYPING; KILLER CELLS, NATURAL; LYMPHOCYTE COUNT; MALE; MIDDLE AGED; MYCOBACTERIUM TUBERCULOSIS; PROGRAMMED CELL DEATH 1 LIGAND 2 PROTEIN; PROGRAMMED CELL DEATH 1 RECEPTOR; T-LYMPHOCYTE SUBSETS; TUBERCULOSIS; YOUNG ADULT;

EID: 84945120679     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0137646     Document Type: Conference Paper

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