메뉴 건너뛰기




Volumn 51, Issue , 2016, Pages 106-116

Xenopus as a model system for studying pancreatic development and diabetes

Author keywords

Diabetes; Embryonic development; Monogenic diabetes; Pancreas; Xenopus

Indexed keywords

AGENESIS; DIABETES MELLITUS; FROG MODEL; GENETIC VARIABILITY; IN VIVO STUDY; NEXT GENERATION SEQUENCING; NONHUMAN; ORGANOGENESIS; PANCREAS; PANCREAS AGENESIS; PANCREAS DEVELOPMENT; REVIEW; XENOPUS; ABNORMALITIES; ANIMAL; DISEASE MODEL; EMBRYOLOGY; GENETICS; HUMAN; MUTATION; PATHOLOGY;

EID: 84960223506     PISSN: 10849521     EISSN: 10963634     Source Type: Journal    
DOI: 10.1016/j.semcdb.2016.01.005     Document Type: Review
Times cited : (10)

References (135)
  • 1
    • 79951648873 scopus 로고    scopus 로고
    • Pancreas organogenesis: from bud to plexus to gland
    • Pan F., Wright C. Pancreas organogenesis: from bud to plexus to gland. Dev. Dyn. 2011, 240:530-565.
    • (2011) Dev. Dyn. , vol.240 , pp. 530-565
    • Pan, F.1    Wright, C.2
  • 2
    • 77949878205 scopus 로고    scopus 로고
    • Cellular plasticity within the pancreas-lessons learned from development
    • Puri S., Hebrok M. Cellular plasticity within the pancreas-lessons learned from development. Dev. Cell 2010, 18:342-356.
    • (2010) Dev. Cell , vol.18 , pp. 342-356
    • Puri, S.1    Hebrok, M.2
  • 3
    • 84876800552 scopus 로고    scopus 로고
    • Control of cell identity in pancreas development and regeneration
    • Stanger B., Hebrok M. Control of cell identity in pancreas development and regeneration. Gastroenterology 2013, 144:1170-1179.
    • (2013) Gastroenterology , vol.144 , pp. 1170-1179
    • Stanger, B.1    Hebrok, M.2
  • 4
    • 84884590826 scopus 로고    scopus 로고
    • Nkx6: 1 is essential for maintaining the functional state of pancreatic beta cells
    • Taylor B., Liu F., Sander M. Nkx6: 1 is essential for maintaining the functional state of pancreatic beta cells. Cell Rep. 2013, 4:1262-1275.
    • (2013) Cell Rep. , vol.4 , pp. 1262-1275
    • Taylor, B.1    Liu, F.2    Sander, M.3
  • 5
    • 84858383401 scopus 로고    scopus 로고
    • Diabetes mellitus and the β cell: the last ten years
    • Ashcroft F., Rorsman P. Diabetes mellitus and the β cell: the last ten years. Cell 2012, 148:1160-1171.
    • (2012) Cell , vol.148 , pp. 1160-1171
    • Ashcroft, F.1    Rorsman, P.2
  • 6
    • 84891848143 scopus 로고    scopus 로고
    • Analysis of transcription factors key for mouse pancreatic development establishes NKX2-2 and MNX1 mutations as causes of neonatal diabetes in man
    • Flanagan S.E., De Franco E., Lango Allen H., Zerah M., Abdul-Rasoul M.M., Edge J.A., et al. Analysis of transcription factors key for mouse pancreatic development establishes NKX2-2 and MNX1 mutations as causes of neonatal diabetes in man. Cell Metab. 2014, 19:146-154.
    • (2014) Cell Metab. , vol.19 , pp. 146-154
    • Flanagan, S.E.1    De Franco, E.2    Lango Allen, H.3    Zerah, M.4    Abdul-Rasoul, M.M.5    Edge, J.A.6
  • 7
    • 41149084500 scopus 로고    scopus 로고
    • Clinical implications of a molecular genetic classification of monogenic beta-cell diabetes
    • Murphy R., Ellard S., Hattersley A. Clinical implications of a molecular genetic classification of monogenic beta-cell diabetes. Nat. Clin. Pract. Endocrinol. Metab. 2008, 4:200-213.
    • (2008) Nat. Clin. Pract. Endocrinol. Metab. , vol.4 , pp. 200-213
    • Murphy, R.1    Ellard, S.2    Hattersley, A.3
  • 8
    • 84896495361 scopus 로고    scopus 로고
    • Many faces of monogenic diabetes
    • Schwitzgebel V.M. Many faces of monogenic diabetes. J. Diabetes Invest. 2014, 5:121-133.
    • (2014) J. Diabetes Invest. , vol.5 , pp. 121-133
    • Schwitzgebel, V.M.1
  • 9
    • 77953263125 scopus 로고    scopus 로고
    • Monogenic forms of diabetes mellitus: an update
    • Vaxillaire M., Froguel P. Monogenic forms of diabetes mellitus: an update. Endocrinol. Nutr. 2009, 56:26-29.
    • (2009) Endocrinol. Nutr. , vol.56 , pp. 26-29
    • Vaxillaire, M.1    Froguel, P.2
  • 10
    • 80755145978 scopus 로고    scopus 로고
    • Neonatal diabetes: an expanding list of genes allows for improved diagnosis and treatment
    • Greeley S.A., Naylor R.N., Philipson L.H., Bell G.I. Neonatal diabetes: an expanding list of genes allows for improved diagnosis and treatment. Curr. Diabetes Rep. 2011, 11:519-532.
    • (2011) Curr. Diabetes Rep. , vol.11 , pp. 519-532
    • Greeley, S.A.1    Naylor, R.N.2    Philipson, L.H.3    Bell, G.I.4
  • 12
    • 34548611497 scopus 로고    scopus 로고
    • From endoderm to pancreas: a multistep journey
    • Spagnoli F.M. From endoderm to pancreas: a multistep journey. Cell Mol. Life Sci. 2007, 64:2378-2390.
    • (2007) Cell Mol. Life Sci. , vol.64 , pp. 2378-2390
    • Spagnoli, F.M.1
  • 13
    • 81055157765 scopus 로고    scopus 로고
    • Xenopus research: metamorphosed by genetics and genomics
    • Harland R., Grainger R. Xenopus research: metamorphosed by genetics and genomics. Trends Genet. 2011, 27:507-515.
    • (2011) Trends Genet. , vol.27 , pp. 507-515
    • Harland, R.1    Grainger, R.2
  • 14
    • 32544436264 scopus 로고    scopus 로고
    • Forgotten and novel aspects in pancreas development
    • Pieler T., Chen Y. Forgotten and novel aspects in pancreas development. Biol. Cell 2006, 98:79-88.
    • (2006) Biol. Cell , vol.98 , pp. 79-88
    • Pieler, T.1    Chen, Y.2
  • 15
    • 84892771868 scopus 로고    scopus 로고
    • Efficient RNA/Cas9-mediated genome editing in Xenopus tropicalis
    • Guo X., Zhang T., Hu Z., Zhang Y., Shi Z., Wang Q., et al. Efficient RNA/Cas9-mediated genome editing in Xenopus tropicalis. Development 2014, 141:707-714.
    • (2014) Development , vol.141 , pp. 707-714
    • Guo, X.1    Zhang, T.2    Hu, Z.3    Zhang, Y.4    Shi, Z.5    Wang, Q.6
  • 16
    • 84867904873 scopus 로고    scopus 로고
    • Efficient targeted gene disruption in Xenopus embryos using engineered transcription activator-like effector nucleases (TALENs)
    • Lei Y., Guo X., Liu Y., Cao Y., Deng Y., Chen X., et al. Efficient targeted gene disruption in Xenopus embryos using engineered transcription activator-like effector nucleases (TALENs). Proc. Natl. Acad. Sci. U. S. A. 2012, 109:17484-17489.
    • (2012) Proc. Natl. Acad. Sci. U. S. A. , vol.109 , pp. 17484-17489
    • Lei, Y.1    Guo, X.2    Liu, Y.3    Cao, Y.4    Deng, Y.5    Chen, X.6
  • 17
    • 84947283866 scopus 로고    scopus 로고
    • Xenopus pax6 mutants affect eye development and other organ systems, and have phenotypic similarities to human aniridia patients
    • Nakayama T., Fisher M., Nakajima K., Odeleye A.O., Zimmerman K.B., Fish M.B., et al. Xenopus pax6 mutants affect eye development and other organ systems, and have phenotypic similarities to human aniridia patients. Dev. Biol. 2015.
    • (2015) Dev. Biol.
    • Nakayama, T.1    Fisher, M.2    Nakajima, K.3    Odeleye, A.O.4    Zimmerman, K.B.5    Fish, M.B.6
  • 18
    • 84928017730 scopus 로고    scopus 로고
    • Targeted gene disruption in Xenopus laevis using CRISPR/Cas9
    • Wang F., Shi Z., Cui Y., Guo X., Shi Y.B., Chen Y. Targeted gene disruption in Xenopus laevis using CRISPR/Cas9. Cell Biosci. 2015, 5:15.
    • (2015) Cell Biosci. , vol.5 , pp. 15
    • Wang, F.1    Shi, Z.2    Cui, Y.3    Guo, X.4    Shi, Y.B.5    Chen, Y.6
  • 19
    • 0029027780 scopus 로고
    • Developmental biology of the pancreas
    • Slack J. Developmental biology of the pancreas. Development 1995, 121:1569-1580.
    • (1995) Development , vol.121 , pp. 1569-1580
    • Slack, J.1
  • 20
    • 84885792555 scopus 로고    scopus 로고
    • Pancreas organogenesis: from lineage determination to morphogenesis
    • Shih H., Wang A., Sander M. Pancreas organogenesis: from lineage determination to morphogenesis. Annu. Rev. Cell Dev. Biol. 2013, 29:81-105.
    • (2013) Annu. Rev. Cell Dev. Biol. , vol.29 , pp. 81-105
    • Shih, H.1    Wang, A.2    Sander, M.3
  • 21
    • 84865191296 scopus 로고    scopus 로고
    • Crosstalk between the developing pancreas and its blood vessels: an evolving dialogue
    • Villasenor A., Cleaver O. Crosstalk between the developing pancreas and its blood vessels: an evolving dialogue. Semin. Cell Dev. Biol. 2012, 23:685-692.
    • (2012) Semin. Cell Dev. Biol. , vol.23 , pp. 685-692
    • Villasenor, A.1    Cleaver, O.2
  • 22
    • 77954323314 scopus 로고    scopus 로고
    • The stunned beta cell: a brief history
    • Ferrannini E. The stunned beta cell: a brief history. Cell Metab. 2010, 11:349-352.
    • (2010) Cell Metab. , vol.11 , pp. 349-352
    • Ferrannini, E.1
  • 23
    • 84871941957 scopus 로고    scopus 로고
    • Diagnosis and classification of diabetes mellitus
    • American Diabetes Association Diagnosis and classification of diabetes mellitus. Diabetes Care 2014, 1(Suppl. 1):S67-S74.
    • (2014) Diabetes Care , vol.1 , pp. S67-S74
  • 24
    • 12344323484 scopus 로고    scopus 로고
    • Type 2 diabetes-a matter of beta-cell life and death?
    • Rhodes C. Type 2 diabetes-a matter of beta-cell life and death?. Science 2005, 307:380-384.
    • (2005) Science , vol.307 , pp. 380-384
    • Rhodes, C.1
  • 25
    • 78649468820 scopus 로고    scopus 로고
    • The genetics of type 2 diabetes: what have we learned from GWAS
    • Billings L., Florez J. The genetics of type 2 diabetes: what have we learned from GWAS. Ann. N. Y. Acad. Sci. 2010, 1212:59-77.
    • (2010) Ann. N. Y. Acad. Sci. , vol.1212 , pp. 59-77
    • Billings, L.1    Florez, J.2
  • 26
    • 84868337361 scopus 로고    scopus 로고
    • Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
    • Morris A.P., Voight B.F., Teslovich T.M., Ferreira T., Segre A.V., Steinthorsdottir V., et al. Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat. Genet. 2012, 44:981-990.
    • (2012) Nat. Genet. , vol.44 , pp. 981-990
    • Morris, A.P.1    Voight, B.F.2    Teslovich, T.M.3    Ferreira, T.4    Segre, A.V.5    Steinthorsdottir, V.6
  • 27
    • 84861914948 scopus 로고    scopus 로고
    • Maintenance of β-cell maturity and plasticity in the adult pancreas
    • Szabat M., Lynn F., Hoffman B., Kieffer T., Allan D., Johnson J. Maintenance of β-cell maturity and plasticity in the adult pancreas. Diabetes 2012, 61:1365-1371.
    • (2012) Diabetes , vol.61 , pp. 1365-1371
    • Szabat, M.1    Lynn, F.2    Hoffman, B.3    Kieffer, T.4    Allan, D.5    Johnson, J.6
  • 28
    • 84866389264 scopus 로고    scopus 로고
    • Pancreatic β cell dedifferentiation as a mechanism of diabetic β cell failure
    • Talchai S., Xuan H.V., Lin L., Sussel L., Accili D. Pancreatic β cell dedifferentiation as a mechanism of diabetic β cell failure. Cell 2012, 150:1223-1234.
    • (2012) Cell , vol.150 , pp. 1223-1234
    • Talchai, S.1    Xuan, H.V.2    Lin, L.3    Sussel, L.4    Accili, D.5
  • 29
    • 59749094454 scopus 로고    scopus 로고
    • Update of mutations in the genes encoding the pancreatic beta-cell K(ATP) channel subunits Kir6.2 (KCNJ11) and sulfonylurea receptor 1 (ABCC8) in diabetes mellitus and hyperinsulinism
    • Flanagan S.E., Clauin S., Bellanne-Chantelot C., de Lonlay P., Harries L.W., Gloyn A.L., et al. Update of mutations in the genes encoding the pancreatic beta-cell K(ATP) channel subunits Kir6.2 (KCNJ11) and sulfonylurea receptor 1 (ABCC8) in diabetes mellitus and hyperinsulinism. Hum. Mutat. 2009, 30:170-180.
    • (2009) Hum. Mutat. , vol.30 , pp. 170-180
    • Flanagan, S.E.1    Clauin, S.2    Bellanne-Chantelot, C.3    de Lonlay, P.4    Harries, L.W.5    Gloyn, A.L.6
  • 30
    • 24144467758 scopus 로고    scopus 로고
    • Activating mutations in Kir6.2 and neonatal diabetes: new clinical syndromes, new scientific insights, and new therapy
    • Hattersley A., Ashcroft F. Activating mutations in Kir6.2 and neonatal diabetes: new clinical syndromes, new scientific insights, and new therapy. Diabetes 2005, 54:2503-2513.
    • (2005) Diabetes , vol.54 , pp. 2503-2513
    • Hattersley, A.1    Ashcroft, F.2
  • 31
    • 10744222821 scopus 로고    scopus 로고
    • Permanent neonatal diabetes caused by glucokinase deficiency: inborn error of the glucose-insulin signaling pathway
    • Njølstad P.R., Sagen J.V., Bjørkhaug L., Odili S., Shehadeh N., Bakry D., et al. Permanent neonatal diabetes caused by glucokinase deficiency: inborn error of the glucose-insulin signaling pathway. Diabetes 2003, 52:2854-2860.
    • (2003) Diabetes , vol.52 , pp. 2854-2860
    • Njølstad, P.R.1    Sagen, J.V.2    Bjørkhaug, L.3    Odili, S.4    Shehadeh, N.5    Bakry, D.6
  • 32
    • 80054923598 scopus 로고    scopus 로고
    • Clinical characterization of a newly described neonatal diabetes syndrome caused by RFX6 mutations
    • Spiegel R., Dobbie A., Hartman C., de Vries L., Ellard S., Shalev S.A. Clinical characterization of a newly described neonatal diabetes syndrome caused by RFX6 mutations. Am. J. Med. Genet. A 2011, 155A:2821-2825.
    • (2011) Am. J. Med. Genet. A , vol.155A , pp. 2821-2825
    • Spiegel, R.1    Dobbie, A.2    Hartman, C.3    de Vries, L.4    Ellard, S.5    Shalev, S.A.6
  • 33
    • 77956799078 scopus 로고    scopus 로고
    • Genetic investigation in an Italian child with an unusual association of atrial septal defect, attributable to a new familial GATA4 gene mutation, and neonatal diabetes due to pancreatic agenesis
    • D'Amato E., Giacopelli F., Giannattasio A., D'Annunzio G., Bocciardi R., Musso M., et al. Genetic investigation in an Italian child with an unusual association of atrial septal defect, attributable to a new familial GATA4 gene mutation, and neonatal diabetes due to pancreatic agenesis. Diabetes Med. 2010, 27:1195-1200.
    • (2010) Diabetes Med. , vol.27 , pp. 1195-1200
    • D'Amato, E.1    Giacopelli, F.2    Giannattasio, A.3    D'Annunzio, G.4    Bocciardi, R.5    Musso, M.6
  • 34
    • 84874432333 scopus 로고    scopus 로고
    • GATA6 mutations cause a broad phenotypic spectrum of diabetes from pancreatic agenesis to adult-onset diabetes without exocrine insufficiency
    • De Franco E., Shaw-Smith C., Flanagan S.E., Shepherd M.H., Consortium I.N., Hattersley A.T., et al. GATA6 mutations cause a broad phenotypic spectrum of diabetes from pancreatic agenesis to adult-onset diabetes without exocrine insufficiency. Diabetes 2013, 62:993-997.
    • (2013) Diabetes , vol.62 , pp. 993-997
    • De Franco, E.1    Shaw-Smith, C.2    Flanagan, S.E.3    Shepherd, M.H.4    Consortium, I.N.5    Hattersley, A.T.6
  • 35
    • 84876800275 scopus 로고    scopus 로고
    • Two novel GATA6 mutations cause childhood-onset diabetes mellitus, pancreas malformation and congenital heart disease
    • Gong M., Simaite D., Kühnen P., Heldmann M., Spagnoli F., Blankenstein O., et al. Two novel GATA6 mutations cause childhood-onset diabetes mellitus, pancreas malformation and congenital heart disease. Horm. Res. Paediatr. 2013, 79:250-256.
    • (2013) Horm. Res. Paediatr. , vol.79 , pp. 250-256
    • Gong, M.1    Simaite, D.2    Kühnen, P.3    Heldmann, M.4    Spagnoli, F.5    Blankenstein, O.6
  • 37
    • 19944431807 scopus 로고    scopus 로고
    • Neonatal diabetes, with hypoplastic pancreas, intestinal atresia and gall bladder hypoplasia: search for the aetiology of a new autosomal recessive syndrome
    • Mitchell J., Punthakee Z., Lo B., Bernard C., Chong K., Newman C., et al. Neonatal diabetes, with hypoplastic pancreas, intestinal atresia and gall bladder hypoplasia: search for the aetiology of a new autosomal recessive syndrome. Diabetologia 2004, 47:2160-2167.
    • (2004) Diabetologia , vol.47 , pp. 2160-2167
    • Mitchell, J.1    Punthakee, Z.2    Lo, B.3    Bernard, C.4    Chong, K.5    Newman, C.6
  • 39
    • 76749108047 scopus 로고    scopus 로고
    • Rfx6 directs islet formation and insulin production in mice and humans
    • Smith S.B., Qu H.-Q., Taleb N., Kishimoto N.Y., Scheel D.W., Lu Y., et al. Rfx6 directs islet formation and insulin production in mice and humans. Nature 2010, 463:775-780.
    • (2010) Nature , vol.463 , pp. 775-780
    • Smith, S.B.1    Qu, H.-Q.2    Taleb, N.3    Kishimoto, N.Y.4    Scheel, D.W.5    Lu, Y.6
  • 43
    • 0031031571 scopus 로고    scopus 로고
    • Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence
    • Stoffers D.A., Zinkin N.T., Stanojevic V., Clarke W.L., Habener J.F. Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence. Nat. Genet. 1997, 15:106-110.
    • (1997) Nat. Genet. , vol.15 , pp. 106-110
    • Stoffers, D.A.1    Zinkin, N.T.2    Stanojevic, V.3    Clarke, W.L.4    Habener, J.F.5
  • 44
    • 0031253820 scopus 로고    scopus 로고
    • Early-onset type-II diabetes mellitus (MODY4) linked to IPF1
    • Stoffers D.A., Ferrer J., Clarke W.L., Habener J.F. Early-onset type-II diabetes mellitus (MODY4) linked to IPF1. Nat. Genet. 1997, 17:138-139.
    • (1997) Nat. Genet. , vol.17 , pp. 138-139
    • Stoffers, D.A.1    Ferrer, J.2    Clarke, W.L.3    Habener, J.F.4
  • 45
    • 10544249874 scopus 로고    scopus 로고
    • Mutations in the hepatocyte nuclear factor-1alpha gene in maturity-onset diabetes of the young (MODY3)
    • Yamagata K., Oda N., Kaisaki P., Menzel S., Furuta H., Vaxillaire M., et al. Mutations in the hepatocyte nuclear factor-1alpha gene in maturity-onset diabetes of the young (MODY3). Nature 1996, 384:455-458.
    • (1996) Nature , vol.384 , pp. 455-458
    • Yamagata, K.1    Oda, N.2    Kaisaki, P.3    Menzel, S.4    Furuta, H.5    Vaxillaire, M.6
  • 47
    • 0033853143 scopus 로고    scopus 로고
    • Development of the pancreas in Xenopus laevis
    • Kelly O., Melton D. Development of the pancreas in Xenopus laevis. Dev. Dyn. 2000, 218:615-627.
    • (2000) Dev. Dyn. , vol.218 , pp. 615-627
    • Kelly, O.1    Melton, D.2
  • 48
    • 66349124401 scopus 로고    scopus 로고
    • Identification of embryonic pancreatic genes using Xenopus DNA microarrays
    • Hayata T., Blitz I.L., Iwata N., Cho K.W. Identification of embryonic pancreatic genes using Xenopus DNA microarrays. Dev. Dyn. 2009, 238:1455-1466.
    • (2009) Dev. Dyn. , vol.238 , pp. 1455-1466
    • Hayata, T.1    Blitz, I.L.2    Iwata, N.3    Cho, K.W.4
  • 49
    • 0035881210 scopus 로고    scopus 로고
    • Endoderm specification and differentiation in Xenopus embryos
    • Horb M., Slack J. Endoderm specification and differentiation in Xenopus embryos. Dev. Biol. 2001, 236:330-343.
    • (2001) Dev. Biol. , vol.236 , pp. 330-343
    • Horb, M.1    Slack, J.2
  • 50
    • 55749083733 scopus 로고    scopus 로고
    • Sfrp5 coordinates foregut specification and morphogenesis by antagonizing both canonical and noncanonical Wnt11 signaling
    • Li Y., Rankin S., Sinner D., Kenny A., Krieg P., Zorn A. Sfrp5 coordinates foregut specification and morphogenesis by antagonizing both canonical and noncanonical Wnt11 signaling. Genes Dev. 2008, 22:3050-3063.
    • (2008) Genes Dev. , vol.22 , pp. 3050-3063
    • Li, Y.1    Rankin, S.2    Sinner, D.3    Kenny, A.4    Krieg, P.5    Zorn, A.6
  • 51
    • 34347341779 scopus 로고    scopus 로고
    • Repression of Wnt/β-catenin signaling in the anterior endoderm is essential for liver and pancreas development
    • McLin V., Rankin S., Zorn A. Repression of Wnt/β-catenin signaling in the anterior endoderm is essential for liver and pancreas development. Development 2007, 134:2207-2217.
    • (2007) Development , vol.134 , pp. 2207-2217
    • McLin, V.1    Rankin, S.2    Zorn, A.3
  • 52
    • 84877109100 scopus 로고    scopus 로고
    • Different thresholds of Wnt-Frizzled 7 signaling coordinate proliferation, morphogenesis and fate of endoderm progenitor cells
    • Zhang Z., Rankin S., Zorn A. Different thresholds of Wnt-Frizzled 7 signaling coordinate proliferation, morphogenesis and fate of endoderm progenitor cells. Dev. Biol. 2013, 378:1-12.
    • (2013) Dev. Biol. , vol.378 , pp. 1-12
    • Zhang, Z.1    Rankin, S.2    Zorn, A.3
  • 53
    • 0033562351 scopus 로고    scopus 로고
    • Anterior endomesoderm specification in Xenopus by Wnt/beta-catenin and TGF-beta signalling pathways
    • Zorn A., Butler K., Gurdon J. Anterior endomesoderm specification in Xenopus by Wnt/beta-catenin and TGF-beta signalling pathways. Dev. Biol. 1999, 209:282-297.
    • (1999) Dev. Biol. , vol.209 , pp. 282-297
    • Zorn, A.1    Butler, K.2    Gurdon, J.3
  • 54
    • 0026310556 scopus 로고
    • Early embryonic development of xenopus laevis
    • Academic Press, B.K. Kay, H.B. Peng (Eds.)
    • Keller R. Early embryonic development of xenopus laevis. Xenopus laevis: Practical Uses in Cell and Molecular Biology 1991, 61-113. Academic Press. B.K. Kay, H.B. Peng (Eds.).
    • (1991) Xenopus laevis: Practical Uses in Cell and Molecular Biology , pp. 61-113
    • Keller, R.1
  • 55
    • 70350225535 scopus 로고    scopus 로고
    • Vertebrate endoderm development and organ formation
    • Zorn A., Wells J. Vertebrate endoderm development and organ formation. Annu. Rev. Cell Dev. Biol. 2009, 25:221-251.
    • (2009) Annu. Rev. Cell Dev. Biol. , vol.25 , pp. 221-251
    • Zorn, A.1    Wells, J.2
  • 56
    • 0033972450 scopus 로고    scopus 로고
    • The xenopus tadpole gut: fate maps and morphogenetic movements
    • Chalmers A., Slack J. The xenopus tadpole gut: fate maps and morphogenetic movements. Development 2000, 127:381-392.
    • (2000) Development , vol.127 , pp. 381-392
    • Chalmers, A.1    Slack, J.2
  • 57
    • 33645912354 scopus 로고    scopus 로고
    • The RNA-binding protein, Vg1RBP, is required for pancreatic fate specification
    • Spagnoli F.M., Brivanlou A.H. The RNA-binding protein, Vg1RBP, is required for pancreatic fate specification. Dev. Biol. 2006, 292:442-456.
    • (2006) Dev. Biol. , vol.292 , pp. 442-456
    • Spagnoli, F.M.1    Brivanlou, A.H.2
  • 58
    • 41649118494 scopus 로고    scopus 로고
    • The Gata5 target, TGIF2, defines the pancreatic region by modulating BMP signals within the endoderm
    • Spagnoli F.M., Brivanlou A.H. The Gata5 target, TGIF2, defines the pancreatic region by modulating BMP signals within the endoderm. Development 2008, 135:451-461.
    • (2008) Development , vol.135 , pp. 451-461
    • Spagnoli, F.M.1    Brivanlou, A.H.2
  • 61
    • 0035694459 scopus 로고    scopus 로고
    • Fgf10 is essential for maintaining the proliferative capacity of epithelial progenitor cells during early pancreatic organogenesis
    • Bhushan A., Itoh N., Kato S., Thiery J., Czernichow P., Bellusci S., et al. Fgf10 is essential for maintaining the proliferative capacity of epithelial progenitor cells during early pancreatic organogenesis. Development 2001, 128:5109-5117.
    • (2001) Development , vol.128 , pp. 5109-5117
    • Bhushan, A.1    Itoh, N.2    Kato, S.3    Thiery, J.4    Czernichow, P.5    Bellusci, S.6
  • 62
    • 0001763783 scopus 로고
    • Epitheliomesenchymal interaction in pancreatic morphogenesis
    • Golosow N., Grobstein C. Epitheliomesenchymal interaction in pancreatic morphogenesis. Dev. Biol. 1962, 4:242-255.
    • (1962) Dev. Biol. , vol.4 , pp. 242-255
    • Golosow, N.1    Grobstein, C.2
  • 64
    • 0036730427 scopus 로고    scopus 로고
    • The role of the transcriptional regulator ptf1a in converting intestinal to pancreatic progenitors
    • Kawaguchi Y., Cooper B., Gannon M., Ray M., Macdonald R., Wright C. The role of the transcriptional regulator ptf1a in converting intestinal to pancreatic progenitors. Nat. Genet. 2002, 32:128-134.
    • (2002) Nat. Genet. , vol.32 , pp. 128-134
    • Kawaguchi, Y.1    Cooper, B.2    Gannon, M.3    Ray, M.4    Macdonald, R.5    Wright, C.6
  • 65
    • 0032860478 scopus 로고    scopus 로고
    • Pancreas dorsal lobe agenesis and abnormal islets of Langerhans in Hlxb9-deficient mice
    • Harrison K.A., Thaler J., Pfaff S.L., Gu H., Kehrl J.H. Pancreas dorsal lobe agenesis and abnormal islets of Langerhans in Hlxb9-deficient mice. Nat. Genet. 1999, 23:71-75.
    • (1999) Nat. Genet. , vol.23 , pp. 71-75
    • Harrison, K.A.1    Thaler, J.2    Pfaff, S.L.3    Gu, H.4    Kehrl, J.H.5
  • 66
    • 0032844643 scopus 로고    scopus 로고
    • Selective agenesis of the dorsal pancreas in mice lacking homeobox gene Hlxb9
    • Li H., Arber S., Jessell T., Edlund H. Selective agenesis of the dorsal pancreas in mice lacking homeobox gene Hlxb9. Nat. Genet. 1999, 23:67-70.
    • (1999) Nat. Genet. , vol.23 , pp. 67-70
    • Li, H.1    Arber, S.2    Jessell, T.3    Edlund, H.4
  • 67
    • 84883633934 scopus 로고    scopus 로고
    • Mutually exclusive signaling signatures define the hepatic and pancreatic progenitor cell lineage divergence
    • Rodríguez-Seguel E., Mah N., Naumann H., Pongrac I., Cerdá-Esteban N., Fontaine J., et al. Mutually exclusive signaling signatures define the hepatic and pancreatic progenitor cell lineage divergence. Genes Dev. 2013, 27:1932-1946.
    • (2013) Genes Dev. , vol.27 , pp. 1932-1946
    • Rodríguez-Seguel, E.1    Mah, N.2    Naumann, H.3    Pongrac, I.4    Cerdá-Esteban, N.5    Fontaine, J.6
  • 68
    • 69549119020 scopus 로고    scopus 로고
    • The tetraspanin Tm4sf3 is localized to the ventral pancreas and regulates fusion of the dorsal and ventral pancreatic buds
    • Jarikji Z., Horb L.D., Shariff F., Mandato C.A., Cho K.W., Horb M.E. The tetraspanin Tm4sf3 is localized to the ventral pancreas and regulates fusion of the dorsal and ventral pancreatic buds. Development 2009, 136:1791-1800.
    • (2009) Development , vol.136 , pp. 1791-1800
    • Jarikji, Z.1    Horb, L.D.2    Shariff, F.3    Mandato, C.A.4    Cho, K.W.5    Horb, M.E.6
  • 69
    • 84861899290 scopus 로고    scopus 로고
    • Homeoprotein hhex-induced conversion of intestinal to ventral pancreatic precursors results in the formation of giant pancreata in Xenopus embryos
    • Zhao H., Han D., Dawid I., Pieler T., Chen Y. Homeoprotein hhex-induced conversion of intestinal to ventral pancreatic precursors results in the formation of giant pancreata in Xenopus embryos. Proc. Natl. Acad. Sci. U. S. A. 2012, 109:8594-8599.
    • (2012) Proc. Natl. Acad. Sci. U. S. A. , vol.109 , pp. 8594-8599
    • Zhao, H.1    Han, D.2    Dawid, I.3    Pieler, T.4    Chen, Y.5
  • 70
    • 84977985950 scopus 로고    scopus 로고
    • Xenopus as a model for GI/pancreas disease
    • Salanga M.C., Horb M.E. Xenopus as a model for GI/pancreas disease. Curr. Pathobiol. Rep. 2015, 3:137-145.
    • (2015) Curr. Pathobiol. Rep. , vol.3 , pp. 137-145
    • Salanga, M.C.1    Horb, M.E.2
  • 71
    • 77955924794 scopus 로고    scopus 로고
    • BrunoL1 regulates endoderm proliferation through translational enhancement of cyclin A2 mRNA
    • Horb L.D., Horb M.E. BrunoL1 regulates endoderm proliferation through translational enhancement of cyclin A2 mRNA. Dev. Biol. 2010, 345:135-145.
    • (2010) Dev. Biol. , vol.345 , pp. 135-145
    • Horb, L.D.1    Horb, M.E.2
  • 72
    • 84876351067 scopus 로고    scopus 로고
    • Gene regulatory networks governing pancreas development
    • Arda H.E., Benitez C.M., Kim S.K. Gene regulatory networks governing pancreas development. Dev. Cell 2013, 25:5-13.
    • (2013) Dev. Cell , vol.25 , pp. 5-13
    • Arda, H.E.1    Benitez, C.M.2    Kim, S.K.3
  • 74
    • 0028149890 scopus 로고
    • Edlund H: insulin-promoter-factor 1 is required for pancreas development in mice
    • Jonsson J., Carlsson L., Edlund T. Edlund H: insulin-promoter-factor 1 is required for pancreas development in mice. Nature 1994, 371:606-609.
    • (1994) Nature , vol.371 , pp. 606-609
    • Jonsson, J.1    Carlsson, L.2    Edlund, T.3
  • 75
    • 0029868156 scopus 로고    scopus 로고
    • PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum
    • Offield M.F., Jetton T.L., Labosky P.A., Ray M., Stein R.W., Magnuson M.A., et al. PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum. Development 1996, 122:983-995.
    • (1996) Development , vol.122 , pp. 983-995
    • Offield, M.F.1    Jetton, T.L.2    Labosky, P.A.3    Ray, M.4    Stein, R.W.5    Magnuson, M.A.6
  • 76
    • 84881218353 scopus 로고    scopus 로고
    • Inactivation of specific β cell transcription factors in type 2 diabetes
    • Guo S., Dai C., Guo M., Taylor B., Harmon J., Sander M., et al. Inactivation of specific β cell transcription factors in type 2 diabetes. J. Clin. Invest. 2013, 123:3305-3316.
    • (2013) J. Clin. Invest. , vol.123 , pp. 3305-3316
    • Guo, S.1    Dai, C.2    Guo, M.3    Taylor, B.4    Harmon, J.5    Sander, M.6
  • 77
    • 84867162947 scopus 로고    scopus 로고
    • GATA believe it: new essential regulators of pancreas development
    • Rodriguez-Segui S., Akerman I., Ferrer J. GATA believe it: new essential regulators of pancreas development. J. Clin. Invest. 2012, 122:3469-3471.
    • (2012) J. Clin. Invest. , vol.122 , pp. 3469-3471
    • Rodriguez-Segui, S.1    Akerman, I.2    Ferrer, J.3
  • 78
    • 84873514082 scopus 로고    scopus 로고
    • Nkx6.1 controls a gene regulatory network required for establishing and maintaining pancreatic Beta cell identity
    • Schaffer A., Taylor B., Benthuysen J., Liu J., Thorel F., Yuan W., et al. Nkx6.1 controls a gene regulatory network required for establishing and maintaining pancreatic Beta cell identity. PLoS Genet. 2013, 9:e1003274.
    • (2013) PLoS Genet. , vol.9 , pp. e1003274
    • Schaffer, A.1    Taylor, B.2    Benthuysen, J.3    Liu, J.4    Thorel, F.5    Yuan, W.6
  • 79
    • 33744814639 scopus 로고    scopus 로고
    • Combined ectopic expression of Pdx1 and Ptf1a/p48 results in the stable conversion of posterior endoderm into endocrine and exocrine pancreatic tissue
    • Afelik S., Chen Y., Pieler T. Combined ectopic expression of Pdx1 and Ptf1a/p48 results in the stable conversion of posterior endoderm into endocrine and exocrine pancreatic tissue. Genes Dev. 2006, 20:1441-1446.
    • (2006) Genes Dev. , vol.20 , pp. 1441-1446
    • Afelik, S.1    Chen, Y.2    Pieler, T.3
  • 80
    • 84944051508 scopus 로고    scopus 로고
    • A gene regulatory network cooperatively controlled by Pdx1 and Sox9 governs lineage allocation of foregut progenitor cells
    • Shih H., Seymour P., Patel N., Xie R., Wang A., Liu P., et al. A gene regulatory network cooperatively controlled by Pdx1 and Sox9 governs lineage allocation of foregut progenitor cells. Cell Rep. 2015, 13:326-336.
    • (2015) Cell Rep. , vol.13 , pp. 326-336
    • Shih, H.1    Seymour, P.2    Patel, N.3    Xie, R.4    Wang, A.5    Liu, P.6
  • 81
    • 0034652287 scopus 로고    scopus 로고
    • Neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas
    • Gradwohl G., Dierich A., LeMeur M., Guillemot F. Neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas. PNAS 2000, 97:1607-1611.
    • (2000) PNAS , vol.97 , pp. 1607-1611
    • Gradwohl, G.1    Dierich, A.2    LeMeur, M.3    Guillemot, F.4
  • 82
    • 0036340074 scopus 로고    scopus 로고
    • Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors
    • Gu G., Dubauskaite J., Melton D. Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors. Development 2002, 129:2447-2457.
    • (2002) Development , vol.129 , pp. 2447-2457
    • Gu, G.1    Dubauskaite, J.2    Melton, D.3
  • 84
    • 34447521981 scopus 로고    scopus 로고
    • The transcription factors Nkx6.1 and Nkx6.2 possess equivalent activities in promoting β-cell fate specification in Pdx1+ pancreatic progenitor cells
    • Nelson S., Schaffer A., Sander M. The transcription factors Nkx6.1 and Nkx6.2 possess equivalent activities in promoting β-cell fate specification in Pdx1+ pancreatic progenitor cells. Development 2007, 134:2491-2500.
    • (2007) Development , vol.134 , pp. 2491-2500
    • Nelson, S.1    Schaffer, A.2    Sander, M.3
  • 85
    • 0031843386 scopus 로고    scopus 로고
    • Mice lacking the homeodomain transcription factor Nkx2: 2 have diabetes due to arrested differentiation of pancreatic beta cells
    • Sussel L., Kalamaras J., Hartigan-O'Connor D., Meneses J., Pedersen R., Rubenstein J., et al. Mice lacking the homeodomain transcription factor Nkx2: 2 have diabetes due to arrested differentiation of pancreatic beta cells. Development 1998, 125:2213-2221.
    • (1998) Development , vol.125 , pp. 2213-2221
    • Sussel, L.1    Kalamaras, J.2    Hartigan-O'Connor, D.3    Meneses, J.4    Pedersen, R.5    Rubenstein, J.6
  • 86
    • 0347722280 scopus 로고    scopus 로고
    • The concerted activities of Pax4 and Nkx2.2 are essential to initiate pancreatic beta-cell differentiation
    • Wang J., Elghazi L., Parker S., Kizilocak H., Asano M., Sussel L., et al. The concerted activities of Pax4 and Nkx2.2 are essential to initiate pancreatic beta-cell differentiation. Dev. Biol. 2004, 266:178-189.
    • (2004) Dev. Biol. , vol.266 , pp. 178-189
    • Wang, J.1    Elghazi, L.2    Parker, S.3    Kizilocak, H.4    Asano, M.5    Sussel, L.6
  • 87
    • 0032525981 scopus 로고    scopus 로고
    • β-Cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the β-cell phenotype and maturity onset diabetes
    • Ahlgren U., Jonsson J., Jonsson L., Simu K., Edlund H. β-Cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the β-cell phenotype and maturity onset diabetes. Genes Dev. 1998, 12:1763-1768.
    • (1998) Genes Dev. , vol.12 , pp. 1763-1768
    • Ahlgren, U.1    Jonsson, J.2    Jonsson, L.3    Simu, K.4    Edlund, H.5
  • 88
    • 33847217554 scopus 로고    scopus 로고
    • Temporal control of neurogenin3 activity in pancreas progenitors reveals competence windows for the generation of different endocrine cell types
    • Johansson K., Dursun U., Jordan N., Gu G., Beermann F., Gradwohl G., et al. Temporal control of neurogenin3 activity in pancreas progenitors reveals competence windows for the generation of different endocrine cell types. Dev. Cell 2007, 12:457-465.
    • (2007) Dev. Cell , vol.12 , pp. 457-465
    • Johansson, K.1    Dursun, U.2    Jordan, N.3    Gu, G.4    Beermann, F.5    Gradwohl, G.6
  • 89
    • 84857999240 scopus 로고    scopus 로고
    • Transient expression of Ngn3 in Xenopus endoderm promotes early and ectopic development of pancreatic beta and delta cells
    • Oropeza D., Horb M. Transient expression of Ngn3 in Xenopus endoderm promotes early and ectopic development of pancreatic beta and delta cells. Genesis 2012, 50:271-285.
    • (2012) Genesis , vol.50 , pp. 271-285
    • Oropeza, D.1    Horb, M.2
  • 90
    • 79551686759 scopus 로고    scopus 로고
    • Functional analysis of Rfx6 and mutant variants associated with neonatal diabetes
    • Pearl E.J., Jarikji Z., Horb M.E. Functional analysis of Rfx6 and mutant variants associated with neonatal diabetes. Dev. Biol. 2011, 351:135-145.
    • (2011) Dev. Biol. , vol.351 , pp. 135-145
    • Pearl, E.J.1    Jarikji, Z.2    Horb, M.E.3
  • 91
    • 0034121735 scopus 로고    scopus 로고
    • Adult insulin- and glucagon-producing cells differentiate from two independent cell lineages
    • Herrera P.L. Adult insulin- and glucagon-producing cells differentiate from two independent cell lineages. Development 2000, 127:2317-2322.
    • (2000) Development , vol.127 , pp. 2317-2322
    • Herrera, P.L.1
  • 92
    • 63349107909 scopus 로고    scopus 로고
    • Remodeling of insulin producing beta-cells during Xenopus laevis metamorphosis
    • Mukhi S., Horb M.E., Brown D.D. Remodeling of insulin producing beta-cells during Xenopus laevis metamorphosis. Dev. Biol. 2009, 328:384-391.
    • (2009) Dev. Biol. , vol.328 , pp. 384-391
    • Mukhi, S.1    Horb, M.E.2    Brown, D.D.3
  • 93
    • 48249117933 scopus 로고    scopus 로고
    • Remodeling the exocrine pancreas at metamorphosis in Xenopus laevis
    • Mukhi S., Mao J., Brown D.D. Remodeling the exocrine pancreas at metamorphosis in Xenopus laevis. Proc. Natl. Acad. Sci. U. S. A. 2008, 105:8962-8967.
    • (2008) Proc. Natl. Acad. Sci. U. S. A. , vol.105 , pp. 8962-8967
    • Mukhi, S.1    Mao, J.2    Brown, D.D.3
  • 94
    • 84876545846 scopus 로고    scopus 로고
    • Thyroid hormone promotes postnatal rat pancreatic beta-cell development and glucose-responsive insulin secretion through MA FA
    • Aguayo-Mazzucato C., Zavacki A.M., Marinelarena A., Hollister-Lock J., El Khattabi I., Marsili A., et al. Thyroid hormone promotes postnatal rat pancreatic beta-cell development and glucose-responsive insulin secretion through MA FA. Diabetes 2013, 62:1569-1580.
    • (2013) Diabetes , vol.62 , pp. 1569-1580
    • Aguayo-Mazzucato, C.1    Zavacki, A.M.2    Marinelarena, A.3    Hollister-Lock, J.4    El Khattabi, I.5    Marsili, A.6
  • 96
    • 84983134468 scopus 로고    scopus 로고
    • Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells
    • Rezania A., Bruin J., Arora P., Rubin A., Batushansky I., Asadi A., et al. Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells. Nat. Biotechnol. 2014, 32:1121-1133.
    • (2014) Nat. Biotechnol. , vol.32 , pp. 1121-1133
    • Rezania, A.1    Bruin, J.2    Arora, P.3    Rubin, A.4    Batushansky, I.5    Asadi, A.6
  • 97
    • 84871646985 scopus 로고    scopus 로고
    • Microarray analysis of Xenopus endoderm expressing Ptf1
    • Bilogan C., Horb M. Microarray analysis of Xenopus endoderm expressing Ptf1. Genesis 2012, 50:853-870.
    • (2012) Genesis , vol.50 , pp. 853-870
    • Bilogan, C.1    Horb, M.2
  • 98
    • 84878613700 scopus 로고    scopus 로고
    • Retinoic acid-activated Ndrg1a represses Wnt/β-catenin signaling to allow Xenopus pancreas, oesophagus, stomach, and duodenum specification
    • Zhang T., Guo X., Chen Y. Retinoic acid-activated Ndrg1a represses Wnt/β-catenin signaling to allow Xenopus pancreas, oesophagus, stomach, and duodenum specification. PLoS One 2013, 8:e65058.
    • (2013) PLoS One , vol.8 , pp. e65058
    • Zhang, T.1    Guo, X.2    Chen, Y.3
  • 99
    • 43549102666 scopus 로고    scopus 로고
    • Neonatal diabetes mellitus
    • Aguilar-Bryan L., Bryan J. Neonatal diabetes mellitus. Endocr. Rev. 2008, 29:265-291.
    • (2008) Endocr. Rev. , vol.29 , pp. 265-291
    • Aguilar-Bryan, L.1    Bryan, J.2
  • 101
    • 2342633204 scopus 로고    scopus 로고
    • Activating mutations in the gene encoding the ATP-sensitive potassium-channel subunit Kir6: 2 and permanent neonatal diabetes
    • Gloyn A., Pearson E., Antcliff J., Proks P., Bruining G., Slingerland A., et al. Activating mutations in the gene encoding the ATP-sensitive potassium-channel subunit Kir6: 2 and permanent neonatal diabetes. N. Engl. J. Med. 2004, 350:1838-1849.
    • (2004) N. Engl. J. Med. , vol.350 , pp. 1838-1849
    • Gloyn, A.1    Pearson, E.2    Antcliff, J.3    Proks, P.4    Bruining, G.5    Slingerland, A.6
  • 102
    • 77956373682 scopus 로고    scopus 로고
    • Homozygous mutations in NEUROD1 are responsible for a novel syndrome of permanent neonatal diabetes and neurological abnormalities
    • Rubio-Cabezas O., Minton J.A., Kantor I., Williams D., Ellard S., Hattersley A.T. Homozygous mutations in NEUROD1 are responsible for a novel syndrome of permanent neonatal diabetes and neurological abnormalities. Diabetes 2010, 59:2326-2331.
    • (2010) Diabetes , vol.59 , pp. 2326-2331
    • Rubio-Cabezas, O.1    Minton, J.A.2    Kantor, I.3    Williams, D.4    Ellard, S.5    Hattersley, A.T.6
  • 103
    • 0024471574 scopus 로고
    • XlHbox 8: a novel Xenopus homeoprotein restricted to a narrow band of endoderm
    • Wright C.V., Schnegelsberg P., De Robertis E.M. XlHbox 8: a novel Xenopus homeoprotein restricted to a narrow band of endoderm. Development 1989, 105:787-794.
    • (1989) Development , vol.105 , pp. 787-794
    • Wright, C.V.1    Schnegelsberg, P.2    De Robertis, E.M.3
  • 105
    • 34047181476 scopus 로고    scopus 로고
    • Differential ability of Ptf1a and Ptf1a-VP16 to convert stomach, duodenum and liver to pancreas
    • Jarikji Z.H., Vanamala S., Beck C.W., Wright C.V., Leach S.D., Horb M.E. Differential ability of Ptf1a and Ptf1a-VP16 to convert stomach, duodenum and liver to pancreas. Dev. Biol. 2007, 304:786-799.
    • (2007) Dev. Biol. , vol.304 , pp. 786-799
    • Jarikji, Z.H.1    Vanamala, S.2    Beck, C.W.3    Wright, C.V.4    Leach, S.D.5    Horb, M.E.6
  • 107
    • 84867174750 scopus 로고    scopus 로고
    • Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis
    • Xuan S., Borok M.J., Decker K.J., Battle M.A., Duncan S.A., Hale M.A., et al. Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis. J. Clin. Invest. 2012, 122:3516-3528.
    • (2012) J. Clin. Invest. , vol.122 , pp. 3516-3528
    • Xuan, S.1    Borok, M.J.2    Decker, K.J.3    Battle, M.A.4    Duncan, S.A.5    Hale, M.A.6
  • 108
    • 33747882568 scopus 로고    scopus 로고
    • Severe pancreas hypoplasia and multicystic renal dysplasia in two human fetuses carrying novel HNF1beta/MODY5 mutations
    • Haumaitre C., Fabre M., Cormier S., Baumann C., Delezoide A.-L., Cereghini S. Severe pancreas hypoplasia and multicystic renal dysplasia in two human fetuses carrying novel HNF1beta/MODY5 mutations. Hum. Mol. Genet. 2006, 15:2363-2375.
    • (2006) Hum. Mol. Genet. , vol.15 , pp. 2363-2375
    • Haumaitre, C.1    Fabre, M.2    Cormier, S.3    Baumann, C.4    Delezoide, A.-L.5    Cereghini, S.6
  • 109
    • 84891525794 scopus 로고    scopus 로고
    • TCF2/HNF-1beta mutations: 3 cases of fetal severe pancreatic agenesis or hypoplasia and multicystic renal dysplasia
    • Body-Bechou D., Loget P., D'Herve D., Le Fiblec B., Grebille A., Le Guern H., et al. TCF2/HNF-1beta mutations: 3 cases of fetal severe pancreatic agenesis or hypoplasia and multicystic renal dysplasia. Prenat. Diagn. 2014, 34:90-93.
    • (2014) Prenat. Diagn. , vol.34 , pp. 90-93
    • Body-Bechou, D.1    Loget, P.2    D'Herve, D.3    Le Fiblec, B.4    Grebille, A.5    Le Guern, H.6
  • 110
    • 0031453186 scopus 로고    scopus 로고
    • Mutation in hepatocyte nuclear factor-1 beta gene (TCF2) associated with MODY
    • Horikawa Y., Iwasaki N., Hara M., Furuta H., Hinokio Y., Cockburn B.N., et al. Mutation in hepatocyte nuclear factor-1 beta gene (TCF2) associated with MODY. Nat. Genet. 1997, 17:384-385.
    • (1997) Nat. Genet. , vol.17 , pp. 384-385
    • Horikawa, Y.1    Iwasaki, N.2    Hara, M.3    Furuta, H.4    Hinokio, Y.5    Cockburn, B.N.6
  • 111
    • 14844352445 scopus 로고    scopus 로고
    • GATA4, 5 and 6 mediate TGFbeta maintenance of endodermal gene expression in Xenopus embryos
    • Afouda B.A., Ciau-Uitz A., Patient R. GATA4, 5 and 6 mediate TGFbeta maintenance of endodermal gene expression in Xenopus embryos. Development 2005, 132:763-774.
    • (2005) Development , vol.132 , pp. 763-774
    • Afouda, B.A.1    Ciau-Uitz, A.2    Patient, R.3
  • 112
    • 50549100087 scopus 로고    scopus 로고
    • GATA4 and GATA5 are essential for heart and liver development in Xenopus embryos
    • Haworth K., Kotecha S., Mohun T., Latinkic B. GATA4 and GATA5 are essential for heart and liver development in Xenopus embryos. BMC Dev. Biol. 2008, 8:74.
    • (2008) BMC Dev. Biol. , vol.8 , pp. 74
    • Haworth, K.1    Kotecha, S.2    Mohun, T.3    Latinkic, B.4
  • 115
    • 0036091898 scopus 로고    scopus 로고
    • PAX6 mutation as a genetic factor common to aniridia and glucose intolerance
    • Yasuda T., Kajimoto Y., Fujitani Y., Watada H., Yamamoto S., Watarai T., et al. PAX6 mutation as a genetic factor common to aniridia and glucose intolerance. Diabetes 2002, 51:224-230.
    • (2002) Diabetes , vol.51 , pp. 224-230
    • Yasuda, T.1    Kajimoto, Y.2    Fujitani, Y.3    Watada, H.4    Yamamoto, S.5    Watarai, T.6
  • 117
    • 79953219761 scopus 로고    scopus 로고
    • Permanent neonatal diabetes and enteric anendocrinosis associated with biallelic mutations in NEUROG3
    • Rubio-Cabezas O., Jensen J., Hodgson M., Codner E., Ellard S., Serup P., et al. Permanent neonatal diabetes and enteric anendocrinosis associated with biallelic mutations in NEUROG3. Diabetes 2011, 60:1349-1353.
    • (2011) Diabetes , vol.60 , pp. 1349-1353
    • Rubio-Cabezas, O.1    Jensen, J.2    Hodgson, M.3    Codner, E.4    Ellard, S.5    Serup, P.6
  • 118
    • 73649093422 scopus 로고    scopus 로고
    • Rfx6 is an Ngn3-dependent winged helix transcription factor required for pancreatic islet cell development
    • Soyer J., Flasse L., Raffelsberger W., Beucher A., Orvain C., Peers B., et al. Rfx6 is an Ngn3-dependent winged helix transcription factor required for pancreatic islet cell development. Development 2010, 137:203-212.
    • (2010) Development , vol.137 , pp. 203-212
    • Soyer, J.1    Flasse, L.2    Raffelsberger, W.3    Beucher, A.4    Orvain, C.5    Peers, B.6
  • 119
    • 84893646612 scopus 로고    scopus 로고
    • Neonatal diabetes, gallbladder agenesis, duodenal atresia, and intestinal malrotation caused by a novel homozygous mutation in RFX6
    • Concepcion J.P., Reh C.S., Daniels M., Liu X., Paz V.P., Ye H., et al. Neonatal diabetes, gallbladder agenesis, duodenal atresia, and intestinal malrotation caused by a novel homozygous mutation in RFX6. Pediatr. Diabetes 2014, 15:67-72.
    • (2014) Pediatr. Diabetes , vol.15 , pp. 67-72
    • Concepcion, J.P.1    Reh, C.S.2    Daniels, M.3    Liu, X.4    Paz, V.P.5    Ye, H.6
  • 121
    • 0033198374 scopus 로고    scopus 로고
    • Pax 6: mastering eye morphogenesis and eye evolution
    • Gehring W.J., Ikeo K. Pax 6: mastering eye morphogenesis and eye evolution. Trends Genet. 1999, 15:371-377.
    • (1999) Trends Genet. , vol.15 , pp. 371-377
    • Gehring, W.J.1    Ikeo, K.2
  • 122
    • 25444528475 scopus 로고    scopus 로고
    • PAX6 mutations: genotype-phenotype correlations
    • Tzoulaki I., White I.M., Hanson I.M. PAX6 mutations: genotype-phenotype correlations. BMC Genet. 2005, 6:27.
    • (2005) BMC Genet. , vol.6 , pp. 27
    • Tzoulaki, I.1    White, I.M.2    Hanson, I.M.3
  • 123
    • 70449380707 scopus 로고    scopus 로고
    • Compound heterozygosity for mutations in PAX6 in a patient with complex brain anomaly, neonatal diabetes mellitus, and microophthalmia
    • Solomon B.D., Pineda-Alvarez D.E., Balog J.Z., Hadley D., Gropman A.L., Nandagopal R., et al. Compound heterozygosity for mutations in PAX6 in a patient with complex brain anomaly, neonatal diabetes mellitus, and microophthalmia. Am. J. Med. Genet. A 2009, 149A:2543-2546.
    • (2009) Am. J. Med. Genet. A , vol.149A , pp. 2543-2546
    • Solomon, B.D.1    Pineda-Alvarez, D.E.2    Balog, J.Z.3    Hadley, D.4    Gropman, A.L.5    Nandagopal, R.6
  • 124
    • 77956282569 scopus 로고    scopus 로고
    • The role of the KATP channel in glucose homeostasis in health and disease: more than meets the islet
    • McTaggart J., Clark R.H., Ashcroft F.M. The role of the KATP channel in glucose homeostasis in health and disease: more than meets the islet. J. Physiol. 2010, 588:3201-3209.
    • (2010) J. Physiol. , vol.588 , pp. 3201-3209
    • McTaggart, J.1    Clark, R.H.2    Ashcroft, F.M.3
  • 125
    • 79959696154 scopus 로고    scopus 로고
    • A conserved tryptophan at the membrane-water interface acts as a gatekeeper for Kir6.2/SUR1 channels and causes neonatal diabetes when mutated
    • Männikkö R., Stansfeld P.J., Ashcroft A.S., Hattersley A.T., Sansom M.S.P., Ellard S., et al. A conserved tryptophan at the membrane-water interface acts as a gatekeeper for Kir6.2/SUR1 channels and causes neonatal diabetes when mutated. J. Physiol. 2011, 589:3071-3083.
    • (2011) J. Physiol. , vol.589 , pp. 3071-3083
    • Männikkö, R.1    Stansfeld, P.J.2    Ashcroft, A.S.3    Hattersley, A.T.4    Sansom, M.S.P.5    Ellard, S.6
  • 126
    • 84884320370 scopus 로고    scopus 로고
    • Molecular mechanism of sulphonylurea block of K(ATP) channels carrying mutations that impair ATP inhibition and cause neonatal diabetes
    • Proks P., de Wet H., Ashcroft F.M. Molecular mechanism of sulphonylurea block of K(ATP) channels carrying mutations that impair ATP inhibition and cause neonatal diabetes. Diabetes 2013, 62:3909-3919.
    • (2013) Diabetes , vol.62 , pp. 3909-3919
    • Proks, P.1    de Wet, H.2    Ashcroft, F.M.3
  • 127
    • 84909602192 scopus 로고    scopus 로고
    • Sulfonylureas suppress the stimulatory action of Mg-nucleotides on Kir6.2/SUR1 but not Kir6.2/SUR2A KATP channels: a mechanistic study
    • Proks P., de Wet H., Ashcroft F.M. Sulfonylureas suppress the stimulatory action of Mg-nucleotides on Kir6.2/SUR1 but not Kir6.2/SUR2A KATP channels: a mechanistic study. J. Gen. Physiol. 2014, 144:469-486.
    • (2014) J. Gen. Physiol. , vol.144 , pp. 469-486
    • Proks, P.1    de Wet, H.2    Ashcroft, F.M.3
  • 128
    • 0027997185 scopus 로고
    • Coexpression of glucose transporters and glucokinase in Xenopus oocytes indicates that both glucose transport and phosphorylation determine glucose utilization
    • Morita H., Yano Y., Niswender K.D., May J.M., Whitesell R.R., Wu L., et al. Coexpression of glucose transporters and glucokinase in Xenopus oocytes indicates that both glucose transport and phosphorylation determine glucose utilization. J. Clin. Invest. 1994, 94:1373-1382.
    • (1994) J. Clin. Invest. , vol.94 , pp. 1373-1382
    • Morita, H.1    Yano, Y.2    Niswender, K.D.3    May, J.M.4    Whitesell, R.R.5    Wu, L.6
  • 129
    • 0041342009 scopus 로고    scopus 로고
    • Distinct molecular and morphogenetic properties of mutations in the human HNF1 gene that lead to defective kidney development
    • Bohn S., Thomas H., Guluzar T., Ellard S., Bingham C., Hattersley A., et al. Distinct molecular and morphogenetic properties of mutations in the human HNF1 gene that lead to defective kidney development. J. Am. Soc. Nephrol. 2003, 14:2033-2041.
    • (2003) J. Am. Soc. Nephrol. , vol.14 , pp. 2033-2041
    • Bohn, S.1    Thomas, H.2    Guluzar, T.3    Ellard, S.4    Bingham, C.5    Hattersley, A.6
  • 132
    • 84907499888 scopus 로고    scopus 로고
    • Recessive mutations in PCBD1 cause a new type of early-onset diabetes
    • Simaite D., Kofent J., Gong M., Rüschendorf F., Jia S., Arn P., et al. Recessive mutations in PCBD1 cause a new type of early-onset diabetes. Diabetes 2014, 63:3557-3564.
    • (2014) Diabetes , vol.63 , pp. 3557-3564
    • Simaite, D.1    Kofent, J.2    Gong, M.3    Rüschendorf, F.4    Jia, S.5    Arn, P.6
  • 134
    • 0347362797 scopus 로고    scopus 로고
    • Wolframin expression induces novel ion channel activity in endoplasmic reticulum membranes and increases intracellular calcium
    • Osman A.A., Saito M., Makepeace C., Permutt M.A., Schlesinger P., Mueckler M. Wolframin expression induces novel ion channel activity in endoplasmic reticulum membranes and increases intracellular calcium. J. Biol. Chem. 2003, 278:52755-52762.
    • (2003) J. Biol. Chem. , vol.278 , pp. 52755-52762
    • Osman, A.A.1    Saito, M.2    Makepeace, C.3    Permutt, M.A.4    Schlesinger, P.5    Mueckler, M.6
  • 135
    • 33744722778 scopus 로고    scopus 로고
    • A heterozygous activating mutation in the sulphonylurea receptor SUR1 (ABCC8) causes neonatal diabetes
    • Proks P., Arnold A.L., Bruining J., Girard C., Flanagan S.E., Larkin B., et al. A heterozygous activating mutation in the sulphonylurea receptor SUR1 (ABCC8) causes neonatal diabetes. Hum. Mol. Genet. 2006, 15:1793-1800.
    • (2006) Hum. Mol. Genet. , vol.15 , pp. 1793-1800
    • Proks, P.1    Arnold, A.L.2    Bruining, J.3    Girard, C.4    Flanagan, S.E.5    Larkin, B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.