-
1
-
-
79951648873
-
Pancreas organogenesis: from bud to plexus to gland
-
Pan F., Wright C. Pancreas organogenesis: from bud to plexus to gland. Dev. Dyn. 2011, 240:530-565.
-
(2011)
Dev. Dyn.
, vol.240
, pp. 530-565
-
-
Pan, F.1
Wright, C.2
-
2
-
-
77949878205
-
Cellular plasticity within the pancreas-lessons learned from development
-
Puri S., Hebrok M. Cellular plasticity within the pancreas-lessons learned from development. Dev. Cell 2010, 18:342-356.
-
(2010)
Dev. Cell
, vol.18
, pp. 342-356
-
-
Puri, S.1
Hebrok, M.2
-
3
-
-
84876800552
-
Control of cell identity in pancreas development and regeneration
-
Stanger B., Hebrok M. Control of cell identity in pancreas development and regeneration. Gastroenterology 2013, 144:1170-1179.
-
(2013)
Gastroenterology
, vol.144
, pp. 1170-1179
-
-
Stanger, B.1
Hebrok, M.2
-
4
-
-
84884590826
-
Nkx6: 1 is essential for maintaining the functional state of pancreatic beta cells
-
Taylor B., Liu F., Sander M. Nkx6: 1 is essential for maintaining the functional state of pancreatic beta cells. Cell Rep. 2013, 4:1262-1275.
-
(2013)
Cell Rep.
, vol.4
, pp. 1262-1275
-
-
Taylor, B.1
Liu, F.2
Sander, M.3
-
5
-
-
84858383401
-
Diabetes mellitus and the β cell: the last ten years
-
Ashcroft F., Rorsman P. Diabetes mellitus and the β cell: the last ten years. Cell 2012, 148:1160-1171.
-
(2012)
Cell
, vol.148
, pp. 1160-1171
-
-
Ashcroft, F.1
Rorsman, P.2
-
6
-
-
84891848143
-
Analysis of transcription factors key for mouse pancreatic development establishes NKX2-2 and MNX1 mutations as causes of neonatal diabetes in man
-
Flanagan S.E., De Franco E., Lango Allen H., Zerah M., Abdul-Rasoul M.M., Edge J.A., et al. Analysis of transcription factors key for mouse pancreatic development establishes NKX2-2 and MNX1 mutations as causes of neonatal diabetes in man. Cell Metab. 2014, 19:146-154.
-
(2014)
Cell Metab.
, vol.19
, pp. 146-154
-
-
Flanagan, S.E.1
De Franco, E.2
Lango Allen, H.3
Zerah, M.4
Abdul-Rasoul, M.M.5
Edge, J.A.6
-
7
-
-
41149084500
-
Clinical implications of a molecular genetic classification of monogenic beta-cell diabetes
-
Murphy R., Ellard S., Hattersley A. Clinical implications of a molecular genetic classification of monogenic beta-cell diabetes. Nat. Clin. Pract. Endocrinol. Metab. 2008, 4:200-213.
-
(2008)
Nat. Clin. Pract. Endocrinol. Metab.
, vol.4
, pp. 200-213
-
-
Murphy, R.1
Ellard, S.2
Hattersley, A.3
-
8
-
-
84896495361
-
Many faces of monogenic diabetes
-
Schwitzgebel V.M. Many faces of monogenic diabetes. J. Diabetes Invest. 2014, 5:121-133.
-
(2014)
J. Diabetes Invest.
, vol.5
, pp. 121-133
-
-
Schwitzgebel, V.M.1
-
9
-
-
77953263125
-
Monogenic forms of diabetes mellitus: an update
-
Vaxillaire M., Froguel P. Monogenic forms of diabetes mellitus: an update. Endocrinol. Nutr. 2009, 56:26-29.
-
(2009)
Endocrinol. Nutr.
, vol.56
, pp. 26-29
-
-
Vaxillaire, M.1
Froguel, P.2
-
10
-
-
80755145978
-
Neonatal diabetes: an expanding list of genes allows for improved diagnosis and treatment
-
Greeley S.A., Naylor R.N., Philipson L.H., Bell G.I. Neonatal diabetes: an expanding list of genes allows for improved diagnosis and treatment. Curr. Diabetes Rep. 2011, 11:519-532.
-
(2011)
Curr. Diabetes Rep.
, vol.11
, pp. 519-532
-
-
Greeley, S.A.1
Naylor, R.N.2
Philipson, L.H.3
Bell, G.I.4
-
11
-
-
66349091034
-
Xenopus pancreas development
-
Pearl E.J., Bilogan C.K., Mukhi S., Brown D.D., Horb M.E. Xenopus pancreas development. Dev. Dyn. 2009, 238:1271-1286.
-
(2009)
Dev. Dyn.
, vol.238
, pp. 1271-1286
-
-
Pearl, E.J.1
Bilogan, C.K.2
Mukhi, S.3
Brown, D.D.4
Horb, M.E.5
-
12
-
-
34548611497
-
From endoderm to pancreas: a multistep journey
-
Spagnoli F.M. From endoderm to pancreas: a multistep journey. Cell Mol. Life Sci. 2007, 64:2378-2390.
-
(2007)
Cell Mol. Life Sci.
, vol.64
, pp. 2378-2390
-
-
Spagnoli, F.M.1
-
13
-
-
81055157765
-
Xenopus research: metamorphosed by genetics and genomics
-
Harland R., Grainger R. Xenopus research: metamorphosed by genetics and genomics. Trends Genet. 2011, 27:507-515.
-
(2011)
Trends Genet.
, vol.27
, pp. 507-515
-
-
Harland, R.1
Grainger, R.2
-
14
-
-
32544436264
-
Forgotten and novel aspects in pancreas development
-
Pieler T., Chen Y. Forgotten and novel aspects in pancreas development. Biol. Cell 2006, 98:79-88.
-
(2006)
Biol. Cell
, vol.98
, pp. 79-88
-
-
Pieler, T.1
Chen, Y.2
-
15
-
-
84892771868
-
Efficient RNA/Cas9-mediated genome editing in Xenopus tropicalis
-
Guo X., Zhang T., Hu Z., Zhang Y., Shi Z., Wang Q., et al. Efficient RNA/Cas9-mediated genome editing in Xenopus tropicalis. Development 2014, 141:707-714.
-
(2014)
Development
, vol.141
, pp. 707-714
-
-
Guo, X.1
Zhang, T.2
Hu, Z.3
Zhang, Y.4
Shi, Z.5
Wang, Q.6
-
16
-
-
84867904873
-
Efficient targeted gene disruption in Xenopus embryos using engineered transcription activator-like effector nucleases (TALENs)
-
Lei Y., Guo X., Liu Y., Cao Y., Deng Y., Chen X., et al. Efficient targeted gene disruption in Xenopus embryos using engineered transcription activator-like effector nucleases (TALENs). Proc. Natl. Acad. Sci. U. S. A. 2012, 109:17484-17489.
-
(2012)
Proc. Natl. Acad. Sci. U. S. A.
, vol.109
, pp. 17484-17489
-
-
Lei, Y.1
Guo, X.2
Liu, Y.3
Cao, Y.4
Deng, Y.5
Chen, X.6
-
17
-
-
84947283866
-
Xenopus pax6 mutants affect eye development and other organ systems, and have phenotypic similarities to human aniridia patients
-
Nakayama T., Fisher M., Nakajima K., Odeleye A.O., Zimmerman K.B., Fish M.B., et al. Xenopus pax6 mutants affect eye development and other organ systems, and have phenotypic similarities to human aniridia patients. Dev. Biol. 2015.
-
(2015)
Dev. Biol.
-
-
Nakayama, T.1
Fisher, M.2
Nakajima, K.3
Odeleye, A.O.4
Zimmerman, K.B.5
Fish, M.B.6
-
18
-
-
84928017730
-
Targeted gene disruption in Xenopus laevis using CRISPR/Cas9
-
Wang F., Shi Z., Cui Y., Guo X., Shi Y.B., Chen Y. Targeted gene disruption in Xenopus laevis using CRISPR/Cas9. Cell Biosci. 2015, 5:15.
-
(2015)
Cell Biosci.
, vol.5
, pp. 15
-
-
Wang, F.1
Shi, Z.2
Cui, Y.3
Guo, X.4
Shi, Y.B.5
Chen, Y.6
-
19
-
-
0029027780
-
Developmental biology of the pancreas
-
Slack J. Developmental biology of the pancreas. Development 1995, 121:1569-1580.
-
(1995)
Development
, vol.121
, pp. 1569-1580
-
-
Slack, J.1
-
20
-
-
84885792555
-
Pancreas organogenesis: from lineage determination to morphogenesis
-
Shih H., Wang A., Sander M. Pancreas organogenesis: from lineage determination to morphogenesis. Annu. Rev. Cell Dev. Biol. 2013, 29:81-105.
-
(2013)
Annu. Rev. Cell Dev. Biol.
, vol.29
, pp. 81-105
-
-
Shih, H.1
Wang, A.2
Sander, M.3
-
21
-
-
84865191296
-
Crosstalk between the developing pancreas and its blood vessels: an evolving dialogue
-
Villasenor A., Cleaver O. Crosstalk between the developing pancreas and its blood vessels: an evolving dialogue. Semin. Cell Dev. Biol. 2012, 23:685-692.
-
(2012)
Semin. Cell Dev. Biol.
, vol.23
, pp. 685-692
-
-
Villasenor, A.1
Cleaver, O.2
-
22
-
-
77954323314
-
The stunned beta cell: a brief history
-
Ferrannini E. The stunned beta cell: a brief history. Cell Metab. 2010, 11:349-352.
-
(2010)
Cell Metab.
, vol.11
, pp. 349-352
-
-
Ferrannini, E.1
-
23
-
-
84871941957
-
Diagnosis and classification of diabetes mellitus
-
American Diabetes Association Diagnosis and classification of diabetes mellitus. Diabetes Care 2014, 1(Suppl. 1):S67-S74.
-
(2014)
Diabetes Care
, vol.1
, pp. S67-S74
-
-
-
24
-
-
12344323484
-
Type 2 diabetes-a matter of beta-cell life and death?
-
Rhodes C. Type 2 diabetes-a matter of beta-cell life and death?. Science 2005, 307:380-384.
-
(2005)
Science
, vol.307
, pp. 380-384
-
-
Rhodes, C.1
-
25
-
-
78649468820
-
The genetics of type 2 diabetes: what have we learned from GWAS
-
Billings L., Florez J. The genetics of type 2 diabetes: what have we learned from GWAS. Ann. N. Y. Acad. Sci. 2010, 1212:59-77.
-
(2010)
Ann. N. Y. Acad. Sci.
, vol.1212
, pp. 59-77
-
-
Billings, L.1
Florez, J.2
-
26
-
-
84868337361
-
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
-
Morris A.P., Voight B.F., Teslovich T.M., Ferreira T., Segre A.V., Steinthorsdottir V., et al. Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat. Genet. 2012, 44:981-990.
-
(2012)
Nat. Genet.
, vol.44
, pp. 981-990
-
-
Morris, A.P.1
Voight, B.F.2
Teslovich, T.M.3
Ferreira, T.4
Segre, A.V.5
Steinthorsdottir, V.6
-
27
-
-
84861914948
-
Maintenance of β-cell maturity and plasticity in the adult pancreas
-
Szabat M., Lynn F., Hoffman B., Kieffer T., Allan D., Johnson J. Maintenance of β-cell maturity and plasticity in the adult pancreas. Diabetes 2012, 61:1365-1371.
-
(2012)
Diabetes
, vol.61
, pp. 1365-1371
-
-
Szabat, M.1
Lynn, F.2
Hoffman, B.3
Kieffer, T.4
Allan, D.5
Johnson, J.6
-
28
-
-
84866389264
-
Pancreatic β cell dedifferentiation as a mechanism of diabetic β cell failure
-
Talchai S., Xuan H.V., Lin L., Sussel L., Accili D. Pancreatic β cell dedifferentiation as a mechanism of diabetic β cell failure. Cell 2012, 150:1223-1234.
-
(2012)
Cell
, vol.150
, pp. 1223-1234
-
-
Talchai, S.1
Xuan, H.V.2
Lin, L.3
Sussel, L.4
Accili, D.5
-
29
-
-
59749094454
-
Update of mutations in the genes encoding the pancreatic beta-cell K(ATP) channel subunits Kir6.2 (KCNJ11) and sulfonylurea receptor 1 (ABCC8) in diabetes mellitus and hyperinsulinism
-
Flanagan S.E., Clauin S., Bellanne-Chantelot C., de Lonlay P., Harries L.W., Gloyn A.L., et al. Update of mutations in the genes encoding the pancreatic beta-cell K(ATP) channel subunits Kir6.2 (KCNJ11) and sulfonylurea receptor 1 (ABCC8) in diabetes mellitus and hyperinsulinism. Hum. Mutat. 2009, 30:170-180.
-
(2009)
Hum. Mutat.
, vol.30
, pp. 170-180
-
-
Flanagan, S.E.1
Clauin, S.2
Bellanne-Chantelot, C.3
de Lonlay, P.4
Harries, L.W.5
Gloyn, A.L.6
-
30
-
-
24144467758
-
Activating mutations in Kir6.2 and neonatal diabetes: new clinical syndromes, new scientific insights, and new therapy
-
Hattersley A., Ashcroft F. Activating mutations in Kir6.2 and neonatal diabetes: new clinical syndromes, new scientific insights, and new therapy. Diabetes 2005, 54:2503-2513.
-
(2005)
Diabetes
, vol.54
, pp. 2503-2513
-
-
Hattersley, A.1
Ashcroft, F.2
-
31
-
-
10744222821
-
Permanent neonatal diabetes caused by glucokinase deficiency: inborn error of the glucose-insulin signaling pathway
-
Njølstad P.R., Sagen J.V., Bjørkhaug L., Odili S., Shehadeh N., Bakry D., et al. Permanent neonatal diabetes caused by glucokinase deficiency: inborn error of the glucose-insulin signaling pathway. Diabetes 2003, 52:2854-2860.
-
(2003)
Diabetes
, vol.52
, pp. 2854-2860
-
-
Njølstad, P.R.1
Sagen, J.V.2
Bjørkhaug, L.3
Odili, S.4
Shehadeh, N.5
Bakry, D.6
-
32
-
-
80054923598
-
Clinical characterization of a newly described neonatal diabetes syndrome caused by RFX6 mutations
-
Spiegel R., Dobbie A., Hartman C., de Vries L., Ellard S., Shalev S.A. Clinical characterization of a newly described neonatal diabetes syndrome caused by RFX6 mutations. Am. J. Med. Genet. A 2011, 155A:2821-2825.
-
(2011)
Am. J. Med. Genet. A
, vol.155A
, pp. 2821-2825
-
-
Spiegel, R.1
Dobbie, A.2
Hartman, C.3
de Vries, L.4
Ellard, S.5
Shalev, S.A.6
-
33
-
-
77956799078
-
Genetic investigation in an Italian child with an unusual association of atrial septal defect, attributable to a new familial GATA4 gene mutation, and neonatal diabetes due to pancreatic agenesis
-
D'Amato E., Giacopelli F., Giannattasio A., D'Annunzio G., Bocciardi R., Musso M., et al. Genetic investigation in an Italian child with an unusual association of atrial septal defect, attributable to a new familial GATA4 gene mutation, and neonatal diabetes due to pancreatic agenesis. Diabetes Med. 2010, 27:1195-1200.
-
(2010)
Diabetes Med.
, vol.27
, pp. 1195-1200
-
-
D'Amato, E.1
Giacopelli, F.2
Giannattasio, A.3
D'Annunzio, G.4
Bocciardi, R.5
Musso, M.6
-
34
-
-
84874432333
-
GATA6 mutations cause a broad phenotypic spectrum of diabetes from pancreatic agenesis to adult-onset diabetes without exocrine insufficiency
-
De Franco E., Shaw-Smith C., Flanagan S.E., Shepherd M.H., Consortium I.N., Hattersley A.T., et al. GATA6 mutations cause a broad phenotypic spectrum of diabetes from pancreatic agenesis to adult-onset diabetes without exocrine insufficiency. Diabetes 2013, 62:993-997.
-
(2013)
Diabetes
, vol.62
, pp. 993-997
-
-
De Franco, E.1
Shaw-Smith, C.2
Flanagan, S.E.3
Shepherd, M.H.4
Consortium, I.N.5
Hattersley, A.T.6
-
35
-
-
84876800275
-
Two novel GATA6 mutations cause childhood-onset diabetes mellitus, pancreas malformation and congenital heart disease
-
Gong M., Simaite D., Kühnen P., Heldmann M., Spagnoli F., Blankenstein O., et al. Two novel GATA6 mutations cause childhood-onset diabetes mellitus, pancreas malformation and congenital heart disease. Horm. Res. Paediatr. 2013, 79:250-256.
-
(2013)
Horm. Res. Paediatr.
, vol.79
, pp. 250-256
-
-
Gong, M.1
Simaite, D.2
Kühnen, P.3
Heldmann, M.4
Spagnoli, F.5
Blankenstein, O.6
-
36
-
-
84655167736
-
GATA6 haploinsufficiency causes pancreatic agenesis in humans
-
Lango Allen H., Flanagan S.E., Shaw-Smith C., De Franco E., Akerman I., Caswell R., et al. GATA6 haploinsufficiency causes pancreatic agenesis in humans. Nat. Genet. 2012, 44:20-22.
-
(2012)
Nat. Genet.
, vol.44
, pp. 20-22
-
-
Lango Allen, H.1
Flanagan, S.E.2
Shaw-Smith, C.3
De Franco, E.4
Akerman, I.5
Caswell, R.6
-
37
-
-
19944431807
-
Neonatal diabetes, with hypoplastic pancreas, intestinal atresia and gall bladder hypoplasia: search for the aetiology of a new autosomal recessive syndrome
-
Mitchell J., Punthakee Z., Lo B., Bernard C., Chong K., Newman C., et al. Neonatal diabetes, with hypoplastic pancreas, intestinal atresia and gall bladder hypoplasia: search for the aetiology of a new autosomal recessive syndrome. Diabetologia 2004, 47:2160-2167.
-
(2004)
Diabetologia
, vol.47
, pp. 2160-2167
-
-
Mitchell, J.1
Punthakee, Z.2
Lo, B.3
Bernard, C.4
Chong, K.5
Newman, C.6
-
38
-
-
9644255692
-
Mutations in PTF1A cause pancreatic and cerebellar agenesis
-
Sellick G.S., Barker K.T., Stolte-Dijkstra I., Fleischmann C., Coleman R.J., Garrett C., et al. Mutations in PTF1A cause pancreatic and cerebellar agenesis. Nat. Genet. 2004, 36:1301-1305.
-
(2004)
Nat. Genet.
, vol.36
, pp. 1301-1305
-
-
Sellick, G.S.1
Barker, K.T.2
Stolte-Dijkstra, I.3
Fleischmann, C.4
Coleman, R.J.5
Garrett, C.6
-
39
-
-
76749108047
-
Rfx6 directs islet formation and insulin production in mice and humans
-
Smith S.B., Qu H.-Q., Taleb N., Kishimoto N.Y., Scheel D.W., Lu Y., et al. Rfx6 directs islet formation and insulin production in mice and humans. Nature 2010, 463:775-780.
-
(2010)
Nature
, vol.463
, pp. 775-780
-
-
Smith, S.B.1
Qu, H.-Q.2
Taleb, N.3
Kishimoto, N.Y.4
Scheel, D.W.5
Lu, Y.6
-
40
-
-
84891347416
-
Recessive mutations in a distal PTF1A enhancer cause isolated pancreatic agenesis
-
Weedon M.N., Cebola I., Patch A.-M., Flanagan S.E., De Franco E., Caswell R., et al. Recessive mutations in a distal PTF1A enhancer cause isolated pancreatic agenesis. Nat. Genet. 2014, 46:61-64.
-
(2014)
Nat. Genet.
, vol.46
, pp. 61-64
-
-
Weedon, M.N.1
Cebola, I.2
Patch, A.-M.3
Flanagan, S.E.4
De Franco, E.5
Caswell, R.6
-
41
-
-
0141787919
-
Agenesis of human pancreas due to decreased half-life of insulin promoter factor 1
-
Schwitzgebel V.M., Mamin A., Brun T., Ritz-Laser B., Zaiko M., Maret A., et al. Agenesis of human pancreas due to decreased half-life of insulin promoter factor 1. J. Clin. Endocrinol. Metab. 2003, 88:4398-4406.
-
(2003)
J. Clin. Endocrinol. Metab.
, vol.88
, pp. 4398-4406
-
-
Schwitzgebel, V.M.1
Mamin, A.2
Brun, T.3
Ritz-Laser, B.4
Zaiko, M.5
Maret, A.6
-
42
-
-
84904752669
-
GATA4 mutations are a cause of neonatal and childhood-onset diabetes
-
Shaw-Smith C., De Franco E., Lango Allen H., Batlle M., Flanagan S.E., Borowiec M., et al. GATA4 mutations are a cause of neonatal and childhood-onset diabetes. Diabetes 2014, 63:2888-2894.
-
(2014)
Diabetes
, vol.63
, pp. 2888-2894
-
-
Shaw-Smith, C.1
De Franco, E.2
Lango Allen, H.3
Batlle, M.4
Flanagan, S.E.5
Borowiec, M.6
-
43
-
-
0031031571
-
Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence
-
Stoffers D.A., Zinkin N.T., Stanojevic V., Clarke W.L., Habener J.F. Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence. Nat. Genet. 1997, 15:106-110.
-
(1997)
Nat. Genet.
, vol.15
, pp. 106-110
-
-
Stoffers, D.A.1
Zinkin, N.T.2
Stanojevic, V.3
Clarke, W.L.4
Habener, J.F.5
-
44
-
-
0031253820
-
Early-onset type-II diabetes mellitus (MODY4) linked to IPF1
-
Stoffers D.A., Ferrer J., Clarke W.L., Habener J.F. Early-onset type-II diabetes mellitus (MODY4) linked to IPF1. Nat. Genet. 1997, 17:138-139.
-
(1997)
Nat. Genet.
, vol.17
, pp. 138-139
-
-
Stoffers, D.A.1
Ferrer, J.2
Clarke, W.L.3
Habener, J.F.4
-
45
-
-
10544249874
-
Mutations in the hepatocyte nuclear factor-1alpha gene in maturity-onset diabetes of the young (MODY3)
-
Yamagata K., Oda N., Kaisaki P., Menzel S., Furuta H., Vaxillaire M., et al. Mutations in the hepatocyte nuclear factor-1alpha gene in maturity-onset diabetes of the young (MODY3). Nature 1996, 384:455-458.
-
(1996)
Nature
, vol.384
, pp. 455-458
-
-
Yamagata, K.1
Oda, N.2
Kaisaki, P.3
Menzel, S.4
Furuta, H.5
Vaxillaire, M.6
-
47
-
-
0033853143
-
Development of the pancreas in Xenopus laevis
-
Kelly O., Melton D. Development of the pancreas in Xenopus laevis. Dev. Dyn. 2000, 218:615-627.
-
(2000)
Dev. Dyn.
, vol.218
, pp. 615-627
-
-
Kelly, O.1
Melton, D.2
-
48
-
-
66349124401
-
Identification of embryonic pancreatic genes using Xenopus DNA microarrays
-
Hayata T., Blitz I.L., Iwata N., Cho K.W. Identification of embryonic pancreatic genes using Xenopus DNA microarrays. Dev. Dyn. 2009, 238:1455-1466.
-
(2009)
Dev. Dyn.
, vol.238
, pp. 1455-1466
-
-
Hayata, T.1
Blitz, I.L.2
Iwata, N.3
Cho, K.W.4
-
49
-
-
0035881210
-
Endoderm specification and differentiation in Xenopus embryos
-
Horb M., Slack J. Endoderm specification and differentiation in Xenopus embryos. Dev. Biol. 2001, 236:330-343.
-
(2001)
Dev. Biol.
, vol.236
, pp. 330-343
-
-
Horb, M.1
Slack, J.2
-
50
-
-
55749083733
-
Sfrp5 coordinates foregut specification and morphogenesis by antagonizing both canonical and noncanonical Wnt11 signaling
-
Li Y., Rankin S., Sinner D., Kenny A., Krieg P., Zorn A. Sfrp5 coordinates foregut specification and morphogenesis by antagonizing both canonical and noncanonical Wnt11 signaling. Genes Dev. 2008, 22:3050-3063.
-
(2008)
Genes Dev.
, vol.22
, pp. 3050-3063
-
-
Li, Y.1
Rankin, S.2
Sinner, D.3
Kenny, A.4
Krieg, P.5
Zorn, A.6
-
51
-
-
34347341779
-
Repression of Wnt/β-catenin signaling in the anterior endoderm is essential for liver and pancreas development
-
McLin V., Rankin S., Zorn A. Repression of Wnt/β-catenin signaling in the anterior endoderm is essential for liver and pancreas development. Development 2007, 134:2207-2217.
-
(2007)
Development
, vol.134
, pp. 2207-2217
-
-
McLin, V.1
Rankin, S.2
Zorn, A.3
-
52
-
-
84877109100
-
Different thresholds of Wnt-Frizzled 7 signaling coordinate proliferation, morphogenesis and fate of endoderm progenitor cells
-
Zhang Z., Rankin S., Zorn A. Different thresholds of Wnt-Frizzled 7 signaling coordinate proliferation, morphogenesis and fate of endoderm progenitor cells. Dev. Biol. 2013, 378:1-12.
-
(2013)
Dev. Biol.
, vol.378
, pp. 1-12
-
-
Zhang, Z.1
Rankin, S.2
Zorn, A.3
-
53
-
-
0033562351
-
Anterior endomesoderm specification in Xenopus by Wnt/beta-catenin and TGF-beta signalling pathways
-
Zorn A., Butler K., Gurdon J. Anterior endomesoderm specification in Xenopus by Wnt/beta-catenin and TGF-beta signalling pathways. Dev. Biol. 1999, 209:282-297.
-
(1999)
Dev. Biol.
, vol.209
, pp. 282-297
-
-
Zorn, A.1
Butler, K.2
Gurdon, J.3
-
54
-
-
0026310556
-
Early embryonic development of xenopus laevis
-
Academic Press, B.K. Kay, H.B. Peng (Eds.)
-
Keller R. Early embryonic development of xenopus laevis. Xenopus laevis: Practical Uses in Cell and Molecular Biology 1991, 61-113. Academic Press. B.K. Kay, H.B. Peng (Eds.).
-
(1991)
Xenopus laevis: Practical Uses in Cell and Molecular Biology
, pp. 61-113
-
-
Keller, R.1
-
55
-
-
70350225535
-
Vertebrate endoderm development and organ formation
-
Zorn A., Wells J. Vertebrate endoderm development and organ formation. Annu. Rev. Cell Dev. Biol. 2009, 25:221-251.
-
(2009)
Annu. Rev. Cell Dev. Biol.
, vol.25
, pp. 221-251
-
-
Zorn, A.1
Wells, J.2
-
56
-
-
0033972450
-
The xenopus tadpole gut: fate maps and morphogenetic movements
-
Chalmers A., Slack J. The xenopus tadpole gut: fate maps and morphogenetic movements. Development 2000, 127:381-392.
-
(2000)
Development
, vol.127
, pp. 381-392
-
-
Chalmers, A.1
Slack, J.2
-
57
-
-
33645912354
-
The RNA-binding protein, Vg1RBP, is required for pancreatic fate specification
-
Spagnoli F.M., Brivanlou A.H. The RNA-binding protein, Vg1RBP, is required for pancreatic fate specification. Dev. Biol. 2006, 292:442-456.
-
(2006)
Dev. Biol.
, vol.292
, pp. 442-456
-
-
Spagnoli, F.M.1
Brivanlou, A.H.2
-
58
-
-
41649118494
-
The Gata5 target, TGIF2, defines the pancreatic region by modulating BMP signals within the endoderm
-
Spagnoli F.M., Brivanlou A.H. The Gata5 target, TGIF2, defines the pancreatic region by modulating BMP signals within the endoderm. Development 2008, 135:451-461.
-
(2008)
Development
, vol.135
, pp. 451-461
-
-
Spagnoli, F.M.1
Brivanlou, A.H.2
-
59
-
-
80053332023
-
Pancreatic mesenchyme regulates epithelial organogenesis throughout development
-
Landsman L., Nijagal A., Whitchurch T., Vanderlaan R., Zimmer W., Mackenzie T., et al. Pancreatic mesenchyme regulates epithelial organogenesis throughout development. PLoS Biol. 2011, 9:e1001143.
-
(2011)
PLoS Biol.
, vol.9
, pp. e1001143
-
-
Landsman, L.1
Nijagal, A.2
Whitchurch, T.3
Vanderlaan, R.4
Zimmer, W.5
Mackenzie, T.6
-
60
-
-
34248171703
-
Control of beta-cell differentiation by the pancreatic mesenchyme
-
Attali M., Stetsyuk V., Basmaciogullari A., Aiello V., Zanta-Boussif M., Duvillie B., et al. Control of beta-cell differentiation by the pancreatic mesenchyme. Diabetes 2007, 56:1248-1258.
-
(2007)
Diabetes
, vol.56
, pp. 1248-1258
-
-
Attali, M.1
Stetsyuk, V.2
Basmaciogullari, A.3
Aiello, V.4
Zanta-Boussif, M.5
Duvillie, B.6
-
61
-
-
0035694459
-
Fgf10 is essential for maintaining the proliferative capacity of epithelial progenitor cells during early pancreatic organogenesis
-
Bhushan A., Itoh N., Kato S., Thiery J., Czernichow P., Bellusci S., et al. Fgf10 is essential for maintaining the proliferative capacity of epithelial progenitor cells during early pancreatic organogenesis. Development 2001, 128:5109-5117.
-
(2001)
Development
, vol.128
, pp. 5109-5117
-
-
Bhushan, A.1
Itoh, N.2
Kato, S.3
Thiery, J.4
Czernichow, P.5
Bellusci, S.6
-
62
-
-
0001763783
-
Epitheliomesenchymal interaction in pancreatic morphogenesis
-
Golosow N., Grobstein C. Epitheliomesenchymal interaction in pancreatic morphogenesis. Dev. Biol. 1962, 4:242-255.
-
(1962)
Dev. Biol.
, vol.4
, pp. 242-255
-
-
Golosow, N.1
Grobstein, C.2
-
63
-
-
13444257370
-
Lack of tcf2/vhnf1 in mice leads to pancreas agenesis
-
Haumaitre C., Barbacci E., Jenny M., Ott M.O., Gradwohl G. Lack of tcf2/vhnf1 in mice leads to pancreas agenesis. Proc. Natl. Acad. Sci. U. S. A. 2005, 102:1490-1495.
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 1490-1495
-
-
Haumaitre, C.1
Barbacci, E.2
Jenny, M.3
Ott, M.O.4
Gradwohl, G.5
-
64
-
-
0036730427
-
The role of the transcriptional regulator ptf1a in converting intestinal to pancreatic progenitors
-
Kawaguchi Y., Cooper B., Gannon M., Ray M., Macdonald R., Wright C. The role of the transcriptional regulator ptf1a in converting intestinal to pancreatic progenitors. Nat. Genet. 2002, 32:128-134.
-
(2002)
Nat. Genet.
, vol.32
, pp. 128-134
-
-
Kawaguchi, Y.1
Cooper, B.2
Gannon, M.3
Ray, M.4
Macdonald, R.5
Wright, C.6
-
65
-
-
0032860478
-
Pancreas dorsal lobe agenesis and abnormal islets of Langerhans in Hlxb9-deficient mice
-
Harrison K.A., Thaler J., Pfaff S.L., Gu H., Kehrl J.H. Pancreas dorsal lobe agenesis and abnormal islets of Langerhans in Hlxb9-deficient mice. Nat. Genet. 1999, 23:71-75.
-
(1999)
Nat. Genet.
, vol.23
, pp. 71-75
-
-
Harrison, K.A.1
Thaler, J.2
Pfaff, S.L.3
Gu, H.4
Kehrl, J.H.5
-
66
-
-
0032844643
-
Selective agenesis of the dorsal pancreas in mice lacking homeobox gene Hlxb9
-
Li H., Arber S., Jessell T., Edlund H. Selective agenesis of the dorsal pancreas in mice lacking homeobox gene Hlxb9. Nat. Genet. 1999, 23:67-70.
-
(1999)
Nat. Genet.
, vol.23
, pp. 67-70
-
-
Li, H.1
Arber, S.2
Jessell, T.3
Edlund, H.4
-
67
-
-
84883633934
-
Mutually exclusive signaling signatures define the hepatic and pancreatic progenitor cell lineage divergence
-
Rodríguez-Seguel E., Mah N., Naumann H., Pongrac I., Cerdá-Esteban N., Fontaine J., et al. Mutually exclusive signaling signatures define the hepatic and pancreatic progenitor cell lineage divergence. Genes Dev. 2013, 27:1932-1946.
-
(2013)
Genes Dev.
, vol.27
, pp. 1932-1946
-
-
Rodríguez-Seguel, E.1
Mah, N.2
Naumann, H.3
Pongrac, I.4
Cerdá-Esteban, N.5
Fontaine, J.6
-
68
-
-
69549119020
-
The tetraspanin Tm4sf3 is localized to the ventral pancreas and regulates fusion of the dorsal and ventral pancreatic buds
-
Jarikji Z., Horb L.D., Shariff F., Mandato C.A., Cho K.W., Horb M.E. The tetraspanin Tm4sf3 is localized to the ventral pancreas and regulates fusion of the dorsal and ventral pancreatic buds. Development 2009, 136:1791-1800.
-
(2009)
Development
, vol.136
, pp. 1791-1800
-
-
Jarikji, Z.1
Horb, L.D.2
Shariff, F.3
Mandato, C.A.4
Cho, K.W.5
Horb, M.E.6
-
69
-
-
84861899290
-
Homeoprotein hhex-induced conversion of intestinal to ventral pancreatic precursors results in the formation of giant pancreata in Xenopus embryos
-
Zhao H., Han D., Dawid I., Pieler T., Chen Y. Homeoprotein hhex-induced conversion of intestinal to ventral pancreatic precursors results in the formation of giant pancreata in Xenopus embryos. Proc. Natl. Acad. Sci. U. S. A. 2012, 109:8594-8599.
-
(2012)
Proc. Natl. Acad. Sci. U. S. A.
, vol.109
, pp. 8594-8599
-
-
Zhao, H.1
Han, D.2
Dawid, I.3
Pieler, T.4
Chen, Y.5
-
70
-
-
84977985950
-
Xenopus as a model for GI/pancreas disease
-
Salanga M.C., Horb M.E. Xenopus as a model for GI/pancreas disease. Curr. Pathobiol. Rep. 2015, 3:137-145.
-
(2015)
Curr. Pathobiol. Rep.
, vol.3
, pp. 137-145
-
-
Salanga, M.C.1
Horb, M.E.2
-
71
-
-
77955924794
-
BrunoL1 regulates endoderm proliferation through translational enhancement of cyclin A2 mRNA
-
Horb L.D., Horb M.E. BrunoL1 regulates endoderm proliferation through translational enhancement of cyclin A2 mRNA. Dev. Biol. 2010, 345:135-145.
-
(2010)
Dev. Biol.
, vol.345
, pp. 135-145
-
-
Horb, L.D.1
Horb, M.E.2
-
72
-
-
84876351067
-
Gene regulatory networks governing pancreas development
-
Arda H.E., Benitez C.M., Kim S.K. Gene regulatory networks governing pancreas development. Dev. Cell 2013, 25:5-13.
-
(2013)
Dev. Cell
, vol.25
, pp. 5-13
-
-
Arda, H.E.1
Benitez, C.M.2
Kim, S.K.3
-
74
-
-
0028149890
-
Edlund H: insulin-promoter-factor 1 is required for pancreas development in mice
-
Jonsson J., Carlsson L., Edlund T. Edlund H: insulin-promoter-factor 1 is required for pancreas development in mice. Nature 1994, 371:606-609.
-
(1994)
Nature
, vol.371
, pp. 606-609
-
-
Jonsson, J.1
Carlsson, L.2
Edlund, T.3
-
75
-
-
0029868156
-
PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum
-
Offield M.F., Jetton T.L., Labosky P.A., Ray M., Stein R.W., Magnuson M.A., et al. PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum. Development 1996, 122:983-995.
-
(1996)
Development
, vol.122
, pp. 983-995
-
-
Offield, M.F.1
Jetton, T.L.2
Labosky, P.A.3
Ray, M.4
Stein, R.W.5
Magnuson, M.A.6
-
76
-
-
84881218353
-
Inactivation of specific β cell transcription factors in type 2 diabetes
-
Guo S., Dai C., Guo M., Taylor B., Harmon J., Sander M., et al. Inactivation of specific β cell transcription factors in type 2 diabetes. J. Clin. Invest. 2013, 123:3305-3316.
-
(2013)
J. Clin. Invest.
, vol.123
, pp. 3305-3316
-
-
Guo, S.1
Dai, C.2
Guo, M.3
Taylor, B.4
Harmon, J.5
Sander, M.6
-
77
-
-
84867162947
-
GATA believe it: new essential regulators of pancreas development
-
Rodriguez-Segui S., Akerman I., Ferrer J. GATA believe it: new essential regulators of pancreas development. J. Clin. Invest. 2012, 122:3469-3471.
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 3469-3471
-
-
Rodriguez-Segui, S.1
Akerman, I.2
Ferrer, J.3
-
78
-
-
84873514082
-
Nkx6.1 controls a gene regulatory network required for establishing and maintaining pancreatic Beta cell identity
-
Schaffer A., Taylor B., Benthuysen J., Liu J., Thorel F., Yuan W., et al. Nkx6.1 controls a gene regulatory network required for establishing and maintaining pancreatic Beta cell identity. PLoS Genet. 2013, 9:e1003274.
-
(2013)
PLoS Genet.
, vol.9
, pp. e1003274
-
-
Schaffer, A.1
Taylor, B.2
Benthuysen, J.3
Liu, J.4
Thorel, F.5
Yuan, W.6
-
79
-
-
33744814639
-
Combined ectopic expression of Pdx1 and Ptf1a/p48 results in the stable conversion of posterior endoderm into endocrine and exocrine pancreatic tissue
-
Afelik S., Chen Y., Pieler T. Combined ectopic expression of Pdx1 and Ptf1a/p48 results in the stable conversion of posterior endoderm into endocrine and exocrine pancreatic tissue. Genes Dev. 2006, 20:1441-1446.
-
(2006)
Genes Dev.
, vol.20
, pp. 1441-1446
-
-
Afelik, S.1
Chen, Y.2
Pieler, T.3
-
80
-
-
84944051508
-
A gene regulatory network cooperatively controlled by Pdx1 and Sox9 governs lineage allocation of foregut progenitor cells
-
Shih H., Seymour P., Patel N., Xie R., Wang A., Liu P., et al. A gene regulatory network cooperatively controlled by Pdx1 and Sox9 governs lineage allocation of foregut progenitor cells. Cell Rep. 2015, 13:326-336.
-
(2015)
Cell Rep.
, vol.13
, pp. 326-336
-
-
Shih, H.1
Seymour, P.2
Patel, N.3
Xie, R.4
Wang, A.5
Liu, P.6
-
81
-
-
0034652287
-
Neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas
-
Gradwohl G., Dierich A., LeMeur M., Guillemot F. Neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas. PNAS 2000, 97:1607-1611.
-
(2000)
PNAS
, vol.97
, pp. 1607-1611
-
-
Gradwohl, G.1
Dierich, A.2
LeMeur, M.3
Guillemot, F.4
-
82
-
-
0036340074
-
Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors
-
Gu G., Dubauskaite J., Melton D. Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors. Development 2002, 129:2447-2457.
-
(2002)
Development
, vol.129
, pp. 2447-2457
-
-
Gu, G.1
Dubauskaite, J.2
Melton, D.3
-
83
-
-
34247183601
-
MafB is required for islet β cell maturation
-
Artner I., Blanchi B., Raum J., Guo M., Kaneko T., Cordes S., et al. MafB is required for islet β cell maturation. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:3853-3858.
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 3853-3858
-
-
Artner, I.1
Blanchi, B.2
Raum, J.3
Guo, M.4
Kaneko, T.5
Cordes, S.6
-
84
-
-
34447521981
-
The transcription factors Nkx6.1 and Nkx6.2 possess equivalent activities in promoting β-cell fate specification in Pdx1+ pancreatic progenitor cells
-
Nelson S., Schaffer A., Sander M. The transcription factors Nkx6.1 and Nkx6.2 possess equivalent activities in promoting β-cell fate specification in Pdx1+ pancreatic progenitor cells. Development 2007, 134:2491-2500.
-
(2007)
Development
, vol.134
, pp. 2491-2500
-
-
Nelson, S.1
Schaffer, A.2
Sander, M.3
-
85
-
-
0031843386
-
Mice lacking the homeodomain transcription factor Nkx2: 2 have diabetes due to arrested differentiation of pancreatic beta cells
-
Sussel L., Kalamaras J., Hartigan-O'Connor D., Meneses J., Pedersen R., Rubenstein J., et al. Mice lacking the homeodomain transcription factor Nkx2: 2 have diabetes due to arrested differentiation of pancreatic beta cells. Development 1998, 125:2213-2221.
-
(1998)
Development
, vol.125
, pp. 2213-2221
-
-
Sussel, L.1
Kalamaras, J.2
Hartigan-O'Connor, D.3
Meneses, J.4
Pedersen, R.5
Rubenstein, J.6
-
86
-
-
0347722280
-
The concerted activities of Pax4 and Nkx2.2 are essential to initiate pancreatic beta-cell differentiation
-
Wang J., Elghazi L., Parker S., Kizilocak H., Asano M., Sussel L., et al. The concerted activities of Pax4 and Nkx2.2 are essential to initiate pancreatic beta-cell differentiation. Dev. Biol. 2004, 266:178-189.
-
(2004)
Dev. Biol.
, vol.266
, pp. 178-189
-
-
Wang, J.1
Elghazi, L.2
Parker, S.3
Kizilocak, H.4
Asano, M.5
Sussel, L.6
-
87
-
-
0032525981
-
β-Cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the β-cell phenotype and maturity onset diabetes
-
Ahlgren U., Jonsson J., Jonsson L., Simu K., Edlund H. β-Cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the β-cell phenotype and maturity onset diabetes. Genes Dev. 1998, 12:1763-1768.
-
(1998)
Genes Dev.
, vol.12
, pp. 1763-1768
-
-
Ahlgren, U.1
Jonsson, J.2
Jonsson, L.3
Simu, K.4
Edlund, H.5
-
88
-
-
33847217554
-
Temporal control of neurogenin3 activity in pancreas progenitors reveals competence windows for the generation of different endocrine cell types
-
Johansson K., Dursun U., Jordan N., Gu G., Beermann F., Gradwohl G., et al. Temporal control of neurogenin3 activity in pancreas progenitors reveals competence windows for the generation of different endocrine cell types. Dev. Cell 2007, 12:457-465.
-
(2007)
Dev. Cell
, vol.12
, pp. 457-465
-
-
Johansson, K.1
Dursun, U.2
Jordan, N.3
Gu, G.4
Beermann, F.5
Gradwohl, G.6
-
89
-
-
84857999240
-
Transient expression of Ngn3 in Xenopus endoderm promotes early and ectopic development of pancreatic beta and delta cells
-
Oropeza D., Horb M. Transient expression of Ngn3 in Xenopus endoderm promotes early and ectopic development of pancreatic beta and delta cells. Genesis 2012, 50:271-285.
-
(2012)
Genesis
, vol.50
, pp. 271-285
-
-
Oropeza, D.1
Horb, M.2
-
90
-
-
79551686759
-
Functional analysis of Rfx6 and mutant variants associated with neonatal diabetes
-
Pearl E.J., Jarikji Z., Horb M.E. Functional analysis of Rfx6 and mutant variants associated with neonatal diabetes. Dev. Biol. 2011, 351:135-145.
-
(2011)
Dev. Biol.
, vol.351
, pp. 135-145
-
-
Pearl, E.J.1
Jarikji, Z.2
Horb, M.E.3
-
91
-
-
0034121735
-
Adult insulin- and glucagon-producing cells differentiate from two independent cell lineages
-
Herrera P.L. Adult insulin- and glucagon-producing cells differentiate from two independent cell lineages. Development 2000, 127:2317-2322.
-
(2000)
Development
, vol.127
, pp. 2317-2322
-
-
Herrera, P.L.1
-
92
-
-
63349107909
-
Remodeling of insulin producing beta-cells during Xenopus laevis metamorphosis
-
Mukhi S., Horb M.E., Brown D.D. Remodeling of insulin producing beta-cells during Xenopus laevis metamorphosis. Dev. Biol. 2009, 328:384-391.
-
(2009)
Dev. Biol.
, vol.328
, pp. 384-391
-
-
Mukhi, S.1
Horb, M.E.2
Brown, D.D.3
-
93
-
-
48249117933
-
Remodeling the exocrine pancreas at metamorphosis in Xenopus laevis
-
Mukhi S., Mao J., Brown D.D. Remodeling the exocrine pancreas at metamorphosis in Xenopus laevis. Proc. Natl. Acad. Sci. U. S. A. 2008, 105:8962-8967.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 8962-8967
-
-
Mukhi, S.1
Mao, J.2
Brown, D.D.3
-
94
-
-
84876545846
-
Thyroid hormone promotes postnatal rat pancreatic beta-cell development and glucose-responsive insulin secretion through MA FA
-
Aguayo-Mazzucato C., Zavacki A.M., Marinelarena A., Hollister-Lock J., El Khattabi I., Marsili A., et al. Thyroid hormone promotes postnatal rat pancreatic beta-cell development and glucose-responsive insulin secretion through MA FA. Diabetes 2013, 62:1569-1580.
-
(2013)
Diabetes
, vol.62
, pp. 1569-1580
-
-
Aguayo-Mazzucato, C.1
Zavacki, A.M.2
Marinelarena, A.3
Hollister-Lock, J.4
El Khattabi, I.5
Marsili, A.6
-
95
-
-
84910673362
-
Generation of functional human pancreatic β cells in vitro
-
Pagliuca F., Millman J., Gürtler M., Segel M., Van Dervort A., Ryu J., et al. Generation of functional human pancreatic β cells in vitro. Cell 2014, 159:428-439.
-
(2014)
Cell
, vol.159
, pp. 428-439
-
-
Pagliuca, F.1
Millman, J.2
Gürtler, M.3
Segel, M.4
Van Dervort, A.5
Ryu, J.6
-
96
-
-
84983134468
-
Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells
-
Rezania A., Bruin J., Arora P., Rubin A., Batushansky I., Asadi A., et al. Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells. Nat. Biotechnol. 2014, 32:1121-1133.
-
(2014)
Nat. Biotechnol.
, vol.32
, pp. 1121-1133
-
-
Rezania, A.1
Bruin, J.2
Arora, P.3
Rubin, A.4
Batushansky, I.5
Asadi, A.6
-
97
-
-
84871646985
-
Microarray analysis of Xenopus endoderm expressing Ptf1
-
Bilogan C., Horb M. Microarray analysis of Xenopus endoderm expressing Ptf1. Genesis 2012, 50:853-870.
-
(2012)
Genesis
, vol.50
, pp. 853-870
-
-
Bilogan, C.1
Horb, M.2
-
98
-
-
84878613700
-
Retinoic acid-activated Ndrg1a represses Wnt/β-catenin signaling to allow Xenopus pancreas, oesophagus, stomach, and duodenum specification
-
Zhang T., Guo X., Chen Y. Retinoic acid-activated Ndrg1a represses Wnt/β-catenin signaling to allow Xenopus pancreas, oesophagus, stomach, and duodenum specification. PLoS One 2013, 8:e65058.
-
(2013)
PLoS One
, vol.8
, pp. e65058
-
-
Zhang, T.1
Guo, X.2
Chen, Y.3
-
100
-
-
33751089560
-
Functional analysis of six Kir6.2 (KCNJ11) mutations causing neonatal diabetes
-
Girard C.A., Shimomura K., Proks P., Absalom N., Castano L., Perez de Nanclares G., et al. Functional analysis of six Kir6.2 (KCNJ11) mutations causing neonatal diabetes. Pflugers Arch. 2006, 453:323-332.
-
(2006)
Pflugers Arch.
, vol.453
, pp. 323-332
-
-
Girard, C.A.1
Shimomura, K.2
Proks, P.3
Absalom, N.4
Castano, L.5
Perez de Nanclares, G.6
-
101
-
-
2342633204
-
Activating mutations in the gene encoding the ATP-sensitive potassium-channel subunit Kir6: 2 and permanent neonatal diabetes
-
Gloyn A., Pearson E., Antcliff J., Proks P., Bruining G., Slingerland A., et al. Activating mutations in the gene encoding the ATP-sensitive potassium-channel subunit Kir6: 2 and permanent neonatal diabetes. N. Engl. J. Med. 2004, 350:1838-1849.
-
(2004)
N. Engl. J. Med.
, vol.350
, pp. 1838-1849
-
-
Gloyn, A.1
Pearson, E.2
Antcliff, J.3
Proks, P.4
Bruining, G.5
Slingerland, A.6
-
102
-
-
77956373682
-
Homozygous mutations in NEUROD1 are responsible for a novel syndrome of permanent neonatal diabetes and neurological abnormalities
-
Rubio-Cabezas O., Minton J.A., Kantor I., Williams D., Ellard S., Hattersley A.T. Homozygous mutations in NEUROD1 are responsible for a novel syndrome of permanent neonatal diabetes and neurological abnormalities. Diabetes 2010, 59:2326-2331.
-
(2010)
Diabetes
, vol.59
, pp. 2326-2331
-
-
Rubio-Cabezas, O.1
Minton, J.A.2
Kantor, I.3
Williams, D.4
Ellard, S.5
Hattersley, A.T.6
-
103
-
-
0024471574
-
XlHbox 8: a novel Xenopus homeoprotein restricted to a narrow band of endoderm
-
Wright C.V., Schnegelsberg P., De Robertis E.M. XlHbox 8: a novel Xenopus homeoprotein restricted to a narrow band of endoderm. Development 1989, 105:787-794.
-
(1989)
Development
, vol.105
, pp. 787-794
-
-
Wright, C.V.1
Schnegelsberg, P.2
De Robertis, E.M.3
-
104
-
-
84942162894
-
Human pancreas development
-
Jennings R., Berry A., Strutt J., Gerrard D., Hanley N. Human pancreas development. Development 2015, 142:3126-3137.
-
(2015)
Development
, vol.142
, pp. 3126-3137
-
-
Jennings, R.1
Berry, A.2
Strutt, J.3
Gerrard, D.4
Hanley, N.5
-
105
-
-
34047181476
-
Differential ability of Ptf1a and Ptf1a-VP16 to convert stomach, duodenum and liver to pancreas
-
Jarikji Z.H., Vanamala S., Beck C.W., Wright C.V., Leach S.D., Horb M.E. Differential ability of Ptf1a and Ptf1a-VP16 to convert stomach, duodenum and liver to pancreas. Dev. Biol. 2007, 304:786-799.
-
(2007)
Dev. Biol.
, vol.304
, pp. 786-799
-
-
Jarikji, Z.H.1
Vanamala, S.2
Beck, C.W.3
Wright, C.V.4
Leach, S.D.5
Horb, M.E.6
-
106
-
-
84867152330
-
GATA4 and GATA6 control mouse pancreas organogenesis
-
Carrasco M., Delgado I., Soria B., Martin F., Rojas A. GATA4 and GATA6 control mouse pancreas organogenesis. J. Clin. Invest. 2012, 122:3504-3515.
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 3504-3515
-
-
Carrasco, M.1
Delgado, I.2
Soria, B.3
Martin, F.4
Rojas, A.5
-
107
-
-
84867174750
-
Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis
-
Xuan S., Borok M.J., Decker K.J., Battle M.A., Duncan S.A., Hale M.A., et al. Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis. J. Clin. Invest. 2012, 122:3516-3528.
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 3516-3528
-
-
Xuan, S.1
Borok, M.J.2
Decker, K.J.3
Battle, M.A.4
Duncan, S.A.5
Hale, M.A.6
-
108
-
-
33747882568
-
Severe pancreas hypoplasia and multicystic renal dysplasia in two human fetuses carrying novel HNF1beta/MODY5 mutations
-
Haumaitre C., Fabre M., Cormier S., Baumann C., Delezoide A.-L., Cereghini S. Severe pancreas hypoplasia and multicystic renal dysplasia in two human fetuses carrying novel HNF1beta/MODY5 mutations. Hum. Mol. Genet. 2006, 15:2363-2375.
-
(2006)
Hum. Mol. Genet.
, vol.15
, pp. 2363-2375
-
-
Haumaitre, C.1
Fabre, M.2
Cormier, S.3
Baumann, C.4
Delezoide, A.-L.5
Cereghini, S.6
-
109
-
-
84891525794
-
TCF2/HNF-1beta mutations: 3 cases of fetal severe pancreatic agenesis or hypoplasia and multicystic renal dysplasia
-
Body-Bechou D., Loget P., D'Herve D., Le Fiblec B., Grebille A., Le Guern H., et al. TCF2/HNF-1beta mutations: 3 cases of fetal severe pancreatic agenesis or hypoplasia and multicystic renal dysplasia. Prenat. Diagn. 2014, 34:90-93.
-
(2014)
Prenat. Diagn.
, vol.34
, pp. 90-93
-
-
Body-Bechou, D.1
Loget, P.2
D'Herve, D.3
Le Fiblec, B.4
Grebille, A.5
Le Guern, H.6
-
110
-
-
0031453186
-
Mutation in hepatocyte nuclear factor-1 beta gene (TCF2) associated with MODY
-
Horikawa Y., Iwasaki N., Hara M., Furuta H., Hinokio Y., Cockburn B.N., et al. Mutation in hepatocyte nuclear factor-1 beta gene (TCF2) associated with MODY. Nat. Genet. 1997, 17:384-385.
-
(1997)
Nat. Genet.
, vol.17
, pp. 384-385
-
-
Horikawa, Y.1
Iwasaki, N.2
Hara, M.3
Furuta, H.4
Hinokio, Y.5
Cockburn, B.N.6
-
111
-
-
14844352445
-
GATA4, 5 and 6 mediate TGFbeta maintenance of endodermal gene expression in Xenopus embryos
-
Afouda B.A., Ciau-Uitz A., Patient R. GATA4, 5 and 6 mediate TGFbeta maintenance of endodermal gene expression in Xenopus embryos. Development 2005, 132:763-774.
-
(2005)
Development
, vol.132
, pp. 763-774
-
-
Afouda, B.A.1
Ciau-Uitz, A.2
Patient, R.3
-
112
-
-
50549100087
-
GATA4 and GATA5 are essential for heart and liver development in Xenopus embryos
-
Haworth K., Kotecha S., Mohun T., Latinkic B. GATA4 and GATA5 are essential for heart and liver development in Xenopus embryos. BMC Dev. Biol. 2008, 8:74.
-
(2008)
BMC Dev. Biol.
, vol.8
, pp. 74
-
-
Haworth, K.1
Kotecha, S.2
Mohun, T.3
Latinkic, B.4
-
113
-
-
0033749652
-
A role for GATA5 in Xenopus endoderm specification
-
Weber H., Symes C.E., Walmsley M.E., Rodaway A.R., Patient R.K. A role for GATA5 in Xenopus endoderm specification. Development 2000, 127:4345-4360.
-
(2000)
Development
, vol.127
, pp. 4345-4360
-
-
Weber, H.1
Symes, C.E.2
Walmsley, M.E.3
Rodaway, A.R.4
Patient, R.K.5
-
114
-
-
33746093870
-
Mutant neurogenin-3 in congenital malabsorptive diarrhea
-
Wang J., Cortina G., Wu S.V., Tran R., Cho J.-H., Tsai M.-J., et al. Mutant neurogenin-3 in congenital malabsorptive diarrhea. N. Engl. J. Med. 2006, 355:270-280.
-
(2006)
N. Engl. J. Med.
, vol.355
, pp. 270-280
-
-
Wang, J.1
Cortina, G.2
Wu, S.V.3
Tran, R.4
Cho, J.-H.5
Tsai, M.-J.6
-
115
-
-
0036091898
-
PAX6 mutation as a genetic factor common to aniridia and glucose intolerance
-
Yasuda T., Kajimoto Y., Fujitani Y., Watada H., Yamamoto S., Watarai T., et al. PAX6 mutation as a genetic factor common to aniridia and glucose intolerance. Diabetes 2002, 51:224-230.
-
(2002)
Diabetes
, vol.51
, pp. 224-230
-
-
Yasuda, T.1
Kajimoto, Y.2
Fujitani, Y.3
Watada, H.4
Yamamoto, S.5
Watarai, T.6
-
116
-
-
34247519644
-
Mutant neurogenin-3 in congenital malabsorptive diarrhea
-
Jensen J., Rosenberg L., Hecksher-Sørensen J., Serup P. Mutant neurogenin-3 in congenital malabsorptive diarrhea. N. Engl. J. Med. 2006, 356:1781-1782.
-
(2006)
N. Engl. J. Med.
, vol.356
, pp. 1781-1782
-
-
Jensen, J.1
Rosenberg, L.2
Hecksher-Sørensen, J.3
Serup, P.4
-
117
-
-
79953219761
-
Permanent neonatal diabetes and enteric anendocrinosis associated with biallelic mutations in NEUROG3
-
Rubio-Cabezas O., Jensen J., Hodgson M., Codner E., Ellard S., Serup P., et al. Permanent neonatal diabetes and enteric anendocrinosis associated with biallelic mutations in NEUROG3. Diabetes 2011, 60:1349-1353.
-
(2011)
Diabetes
, vol.60
, pp. 1349-1353
-
-
Rubio-Cabezas, O.1
Jensen, J.2
Hodgson, M.3
Codner, E.4
Ellard, S.5
Serup, P.6
-
118
-
-
73649093422
-
Rfx6 is an Ngn3-dependent winged helix transcription factor required for pancreatic islet cell development
-
Soyer J., Flasse L., Raffelsberger W., Beucher A., Orvain C., Peers B., et al. Rfx6 is an Ngn3-dependent winged helix transcription factor required for pancreatic islet cell development. Development 2010, 137:203-212.
-
(2010)
Development
, vol.137
, pp. 203-212
-
-
Soyer, J.1
Flasse, L.2
Raffelsberger, W.3
Beucher, A.4
Orvain, C.5
Peers, B.6
-
119
-
-
84893646612
-
Neonatal diabetes, gallbladder agenesis, duodenal atresia, and intestinal malrotation caused by a novel homozygous mutation in RFX6
-
Concepcion J.P., Reh C.S., Daniels M., Liu X., Paz V.P., Ye H., et al. Neonatal diabetes, gallbladder agenesis, duodenal atresia, and intestinal malrotation caused by a novel homozygous mutation in RFX6. Pediatr. Diabetes 2014, 15:67-72.
-
(2014)
Pediatr. Diabetes
, vol.15
, pp. 67-72
-
-
Concepcion, J.P.1
Reh, C.S.2
Daniels, M.3
Liu, X.4
Paz, V.P.5
Ye, H.6
-
121
-
-
0033198374
-
Pax 6: mastering eye morphogenesis and eye evolution
-
Gehring W.J., Ikeo K. Pax 6: mastering eye morphogenesis and eye evolution. Trends Genet. 1999, 15:371-377.
-
(1999)
Trends Genet.
, vol.15
, pp. 371-377
-
-
Gehring, W.J.1
Ikeo, K.2
-
122
-
-
25444528475
-
PAX6 mutations: genotype-phenotype correlations
-
Tzoulaki I., White I.M., Hanson I.M. PAX6 mutations: genotype-phenotype correlations. BMC Genet. 2005, 6:27.
-
(2005)
BMC Genet.
, vol.6
, pp. 27
-
-
Tzoulaki, I.1
White, I.M.2
Hanson, I.M.3
-
123
-
-
70449380707
-
Compound heterozygosity for mutations in PAX6 in a patient with complex brain anomaly, neonatal diabetes mellitus, and microophthalmia
-
Solomon B.D., Pineda-Alvarez D.E., Balog J.Z., Hadley D., Gropman A.L., Nandagopal R., et al. Compound heterozygosity for mutations in PAX6 in a patient with complex brain anomaly, neonatal diabetes mellitus, and microophthalmia. Am. J. Med. Genet. A 2009, 149A:2543-2546.
-
(2009)
Am. J. Med. Genet. A
, vol.149A
, pp. 2543-2546
-
-
Solomon, B.D.1
Pineda-Alvarez, D.E.2
Balog, J.Z.3
Hadley, D.4
Gropman, A.L.5
Nandagopal, R.6
-
124
-
-
77956282569
-
The role of the KATP channel in glucose homeostasis in health and disease: more than meets the islet
-
McTaggart J., Clark R.H., Ashcroft F.M. The role of the KATP channel in glucose homeostasis in health and disease: more than meets the islet. J. Physiol. 2010, 588:3201-3209.
-
(2010)
J. Physiol.
, vol.588
, pp. 3201-3209
-
-
McTaggart, J.1
Clark, R.H.2
Ashcroft, F.M.3
-
125
-
-
79959696154
-
A conserved tryptophan at the membrane-water interface acts as a gatekeeper for Kir6.2/SUR1 channels and causes neonatal diabetes when mutated
-
Männikkö R., Stansfeld P.J., Ashcroft A.S., Hattersley A.T., Sansom M.S.P., Ellard S., et al. A conserved tryptophan at the membrane-water interface acts as a gatekeeper for Kir6.2/SUR1 channels and causes neonatal diabetes when mutated. J. Physiol. 2011, 589:3071-3083.
-
(2011)
J. Physiol.
, vol.589
, pp. 3071-3083
-
-
Männikkö, R.1
Stansfeld, P.J.2
Ashcroft, A.S.3
Hattersley, A.T.4
Sansom, M.S.P.5
Ellard, S.6
-
126
-
-
84884320370
-
Molecular mechanism of sulphonylurea block of K(ATP) channels carrying mutations that impair ATP inhibition and cause neonatal diabetes
-
Proks P., de Wet H., Ashcroft F.M. Molecular mechanism of sulphonylurea block of K(ATP) channels carrying mutations that impair ATP inhibition and cause neonatal diabetes. Diabetes 2013, 62:3909-3919.
-
(2013)
Diabetes
, vol.62
, pp. 3909-3919
-
-
Proks, P.1
de Wet, H.2
Ashcroft, F.M.3
-
127
-
-
84909602192
-
Sulfonylureas suppress the stimulatory action of Mg-nucleotides on Kir6.2/SUR1 but not Kir6.2/SUR2A KATP channels: a mechanistic study
-
Proks P., de Wet H., Ashcroft F.M. Sulfonylureas suppress the stimulatory action of Mg-nucleotides on Kir6.2/SUR1 but not Kir6.2/SUR2A KATP channels: a mechanistic study. J. Gen. Physiol. 2014, 144:469-486.
-
(2014)
J. Gen. Physiol.
, vol.144
, pp. 469-486
-
-
Proks, P.1
de Wet, H.2
Ashcroft, F.M.3
-
128
-
-
0027997185
-
Coexpression of glucose transporters and glucokinase in Xenopus oocytes indicates that both glucose transport and phosphorylation determine glucose utilization
-
Morita H., Yano Y., Niswender K.D., May J.M., Whitesell R.R., Wu L., et al. Coexpression of glucose transporters and glucokinase in Xenopus oocytes indicates that both glucose transport and phosphorylation determine glucose utilization. J. Clin. Invest. 1994, 94:1373-1382.
-
(1994)
J. Clin. Invest.
, vol.94
, pp. 1373-1382
-
-
Morita, H.1
Yano, Y.2
Niswender, K.D.3
May, J.M.4
Whitesell, R.R.5
Wu, L.6
-
129
-
-
0041342009
-
Distinct molecular and morphogenetic properties of mutations in the human HNF1 gene that lead to defective kidney development
-
Bohn S., Thomas H., Guluzar T., Ellard S., Bingham C., Hattersley A., et al. Distinct molecular and morphogenetic properties of mutations in the human HNF1 gene that lead to defective kidney development. J. Am. Soc. Nephrol. 2003, 14:2033-2041.
-
(2003)
J. Am. Soc. Nephrol.
, vol.14
, pp. 2033-2041
-
-
Bohn, S.1
Thomas, H.2
Guluzar, T.3
Ellard, S.4
Bingham, C.5
Hattersley, A.6
-
130
-
-
12944309912
-
The mutated human gene encoding hepatocyte nuclear factor 1beta inhibits kidney formation in developing Xenopus embryos
-
Wild W., Pogge von Strandmann E., Nastos A., Senkel S., Lingott-Frieg A., Bulman M., et al. The mutated human gene encoding hepatocyte nuclear factor 1beta inhibits kidney formation in developing Xenopus embryos. Proc. Natl. Acad. Sci. U. S. A. 2000, 97:4695-4700.
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 4695-4700
-
-
Wild, W.1
Pogge von Strandmann, E.2
Nastos, A.3
Senkel, S.4
Lingott-Frieg, A.5
Bulman, M.6
-
131
-
-
84896816867
-
Mutations in PCBD1 cause hypomagnesemia and renal magnesium wasting
-
Ferre S., dB J.H., Ferreira P., Germann R., de Klerk J., Lavrijsen M., et al. Mutations in PCBD1 cause hypomagnesemia and renal magnesium wasting. J. Am. Soc. Nephrol. 2014, 25:574-586.
-
(2014)
J. Am. Soc. Nephrol.
, vol.25
, pp. 574-586
-
-
Ferre, S.1
dB, J.H.2
Ferreira, P.3
Germann, R.4
de Klerk, J.5
Lavrijsen, M.6
-
132
-
-
84907499888
-
Recessive mutations in PCBD1 cause a new type of early-onset diabetes
-
Simaite D., Kofent J., Gong M., Rüschendorf F., Jia S., Arn P., et al. Recessive mutations in PCBD1 cause a new type of early-onset diabetes. Diabetes 2014, 63:3557-3564.
-
(2014)
Diabetes
, vol.63
, pp. 3557-3564
-
-
Simaite, D.1
Kofent, J.2
Gong, M.3
Rüschendorf, F.4
Jia, S.5
Arn, P.6
-
133
-
-
84886645129
-
Mutations in SLC2A2 gene reveal hGLUT2 function in pancreatic β cell development
-
Michau A., Guillemain G., Grosfeld A., Vuillaumier-Barrot S., Grand T., Keck M., et al. Mutations in SLC2A2 gene reveal hGLUT2 function in pancreatic β cell development. J. Biol. Chem. 2013, 288:31080-31092.
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 31080-31092
-
-
Michau, A.1
Guillemain, G.2
Grosfeld, A.3
Vuillaumier-Barrot, S.4
Grand, T.5
Keck, M.6
-
134
-
-
0347362797
-
Wolframin expression induces novel ion channel activity in endoplasmic reticulum membranes and increases intracellular calcium
-
Osman A.A., Saito M., Makepeace C., Permutt M.A., Schlesinger P., Mueckler M. Wolframin expression induces novel ion channel activity in endoplasmic reticulum membranes and increases intracellular calcium. J. Biol. Chem. 2003, 278:52755-52762.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 52755-52762
-
-
Osman, A.A.1
Saito, M.2
Makepeace, C.3
Permutt, M.A.4
Schlesinger, P.5
Mueckler, M.6
-
135
-
-
33744722778
-
A heterozygous activating mutation in the sulphonylurea receptor SUR1 (ABCC8) causes neonatal diabetes
-
Proks P., Arnold A.L., Bruining J., Girard C., Flanagan S.E., Larkin B., et al. A heterozygous activating mutation in the sulphonylurea receptor SUR1 (ABCC8) causes neonatal diabetes. Hum. Mol. Genet. 2006, 15:1793-1800.
-
(2006)
Hum. Mol. Genet.
, vol.15
, pp. 1793-1800
-
-
Proks, P.1
Arnold, A.L.2
Bruining, J.3
Girard, C.4
Flanagan, S.E.5
Larkin, B.6
|