RFX6 Regulates Insulin Secretion by Modulating Ca2+ Homeostasis in Human β Cells

Cell Reports

Volumn 9, Issue 6, 2014, Pages 2206-2218

  Chandra, Vikash ^a   Albagli Curiel, Olivier ^a   Hastoy, Benoit ^b   Piccand, Julie ^c   Randriamampita, Clotilde ^d   Vaillant, Emmanuel ^e   Cavé, Hélène ^f   Busiah, Kanetee ^a,g   Froguel, Philippe ^e,h   Vaxillaire, Martine ^e   Rorsman, Patrik ^b   Polak, Michel ^a,g   Scharfmann, Raphael ^a  

^a INSERM   (France)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^d INSTITUT COCHIN   (France)

^e UNIV LILLE   (France)

^f HÔPITAL ROBERT DEBRÉ   (France)

^g HÔPITAL NECKER ENFANTS MALADES   (France)

^h HAMMERSMITH HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL; CALCIUM CHANNEL L TYPE; CALCIUM CHANNEL P TYPE; CALCIUM CHANNEL Q TYPE; CALCIUM CHANNEL T TYPE; MESSENGER RNA; NEUROGENIC DIFFERENTIATION FACTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR MAFB; TRANSCRIPTION FACTOR NKX2.2; TRANSCRIPTION FACTOR PAX6; TRANSCRIPTION FACTOR PDX 1; TRANSCRIPTION FACTOR RFX6; UNCLASSIFIED DRUG; CALCIUM; DNA BINDING PROTEIN; INSULIN; RFX6 PROTEIN, HUMAN;

AMINO ACID SEQUENCE; ARTICLE; CALCIUM CURRENT; CALCIUM HOMEOSTASIS; CELL DIFFERENTIATION; CONTROLLED STUDY; DEPOLARIZATION; DIABETES MELLITUS; DIMERIZATION; DOWN REGULATION; EXOCYTOSIS; FLOW CYTOMETRY; GAIN OF FUNCTION MUTATION; GENE EXPRESSION; GENETIC TRANSCRIPTION; HOMOZYGOSITY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; INSULIN RELEASE; MICROARRAY ANALYSIS; MISSENSE MUTATION; NEWBORN DISEASE; NUCLEAR LOCALIZATION SIGNAL; NUCLEOTIDE SEQUENCE; PANCREAS ISLET BETA CELL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN MOTIF; REAL TIME POLYMERASE CHAIN REACTION; SEQUENCE ALIGNMENT; CELL LINE; GENETICS; HOMEOSTASIS; METABOLISM;

CALCIUM; CALCIUM CHANNELS, L-TYPE; CELL LINE; DNA-BINDING PROTEINS; EXOCYTOSIS; HOMEOSTASIS; HUMANS; INSULIN; INSULIN-SECRETING CELLS; MUTATION, MISSENSE; TRANSCRIPTION FACTORS;

EID: 84919846983     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2014.11.010     Document Type: Article

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