Remodeling the exocrine pancreas at metamorphosis in Xenopus laevis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 26, 2008, Pages 8962-8967

  Mukhi, Sandeep ^a   Mao, Jinzhe ^b   Brown, Donald D ^a  

^a GEOPHYSICAL LABORATORY   (United States)

^b CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

Author keywords

Dedifferentiation; Gene expression; Thyroid hormone; Thyroid hormone receptor dominant negative

Indexed keywords

MESSENGER RNA; THYROID HORMONE; TRANSCRIPTION FACTOR HES 1; TRANSCRIPTION FACTOR PDX 1; ZYMOGEN GRANULE; GREEN FLUORESCENT PROTEIN; LIOTHYRONINE; PANCREATIC ELASTASE; XENOPUS PROTEIN;

ACINAR CELL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE; HES 1 GENE; MALE; METAMORPHOSIS; NONHUMAN; NOTCH1 GENE; PANCREAS; PDX 1 GENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; XENOPUS LAEVIS; ANIMAL; BIOLOGICAL MODEL; CELL DEDIFFERENTIATION; CYTOLOGY; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; LARVA; METABOLISM; PANCREAS DUCT; RAT; TRANSGENE;

ANURA; VERTEBRATA; XENOPUS LAEVIS;

ANIMALS; CELL DEDIFFERENTIATION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GREEN FLUORESCENT PROTEINS; LARVA; METAMORPHOSIS, BIOLOGICAL; MODELS, GENETIC; PANCREAS, EXOCRINE; PANCREATIC DUCTS; PANCREATIC ELASTASE; RATS; TRANSGENES; TRIIODOTHYRONINE; XENOPUS LAEVIS; XENOPUS PROTEINS;

EID: 48249117933     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0803569105     Document Type: Article

References (45)

1. Leloup J, Buscaglia M (1977) Triiodothyronine: Metamorphosis hormone of the amphibians. C R Acad Sci 284:2261-2263.
2. Dodd MHI, Dodd JM (1976) The Biology of Metamorphosis (Academic, New York).
3. Schreiber AM, Das B, Huang H, Marsh-Armstrong N, Brown DD (2001) Diverse developmental programs of Xenopus laevis metamorphosis are inhibited by a dominant negative thyroid hormone receptor. Proc Natl Acad Sci USA 98:10739-10744.
4. Marsh-Armstrong N, Cai L, Brown DD (2004) Thyroid hormone controls the development of connections between the spinal cord and limbs during Xenopus laevis metamorphosis. Proc Natl Acad Sci USA 101:165-170.
5. Das B, Schreiber AM, Huang H, Brown DD (2002) Multiple thyroid hormone-induced muscle growth and death programs during metamorphosis in Xenopus laevis. Proc Natl Acad Sci USA 99:12230-12235.
6. Cai L, Brown DD (2004) Expression of type II iodothyronine deiodinase marks the time that a tissue responds to thyroid hormone-induced metamorphosis in Xenopus laevis. Dev Biol 266:87-95.
7. Brown DD, et al. (2005) Thyroid hormone controls multiple independent programs required for limb development in Xenopus laevis metamorphosis. Proc Natl Acad Sci USA 102:12455-12458.
8. Horb ME, Slack JM (2002) Expression of amylase and other pancreatic genes in Xenopus. Mech Dev 113:153-157.
9. Bollin E, Jr, Carlson CA, Kim KH (1973) Anuran pancreas development during thyroxine-induced metamorphosis of Rana catesbeiana: RNA metabolism during the regressive phase of pancreas development. Dev Biol 31:185-191.
10. Milano EG, Chimenti C (1995) Morphogenesis of the pancreas of Bufo bufo during metamorphosis. Gen Comp Endocrinol 97:239-249.
11. Leone F, Lambert-Gardini S, Sartori C, Scapin S (1976) Ultrastructural analysis of some functional aspects of Xenopus laevis pancreas during development and metamorphosis. J Embryol Exp Morphol 36:711-724.
12. Shi YB, Brown DD (1990) Developmental and thyroid hormone-dependent regulation of pancreatic genes in Xenopus laevis. Genes Dev 4:1107-1113.
13. Lin JW, et al. (2004) Differential requirement for ptf1a in endocrine and exocrine lineages of developing zebrafish pancreas. Dev Biol 270:474-486.
14. Guz Y, et al. (1995) Expression of murine STF-1, a putative insulin gene transcription factor, in β-cells of pancreas, duodenal epithelium, and pancreatic exocrine and endocrine progenitors during ontogeny. Development 121:11-18.
15. Habener JF, Stoffers DA (1998) A newly discovered role of transcription factors involved in pancreas development and the pathogenesis of diabetes mellitus. Proc Assoc Am Physicians 110:12-21.
16. Murtaugh LC, Stanger BZ, Kwan KM, Melton DA (2003) Notch signaling controls multiple steps of pancreatic differentiation. Proc Natl Acad Sci USA 100:14920-14925.
17. Hald J, et al. (2003) Activated Notch1 prevents differentiation of pancreatic acinar cells and attenuate endocrine development. Dev Biol 260:426-437.
18. Esni F, et al. (2004) Notch inhibits Ptf1 function and acinar cell differentiation in developing mouse and zebrafish pancreas. Development 131:4213-4224.
19. Ghosh B, Leach SD (2006) Interactions between Hairy/Enhancer of Split-related proteins and the pancreatic transcription factor Ptf1-p48 modulate function of the PTF1 transcriptional complex. Biochem J 393:679-685.
20. Egerbacher M, Bock P (1997) Morphology of the pancreatic duct system in mammals. Microsc Res Tech 37:407-417.
21. Lohr M, et al. (2001) Immortalized bovine pancreatic duct cells become tumorigenic after transfection with mutant k-ras. Virchows Arch 438:581-590.
22. Janes RG (1937) Studies on the amphibian digestive system II. Comparative histology of the pancreas, following early larval development, in certain species of anura. J Morphol 61:581-611.
23. Race JJ, Robinson C, Terry RJ (1966) The influence of thyroxine on the normal development of pancreas in Rana pipens larvae. J Exp Zool 162:181-192.
24. Jarikji ZH, et al. (2007) Differential ability of Ptf1a and Ptf1a-VP16 to convert stomach, duodenum, and liver to pancreas. Dev Biol 304:786-799.
25. Afelik S, Chen Y, Pieler T (2006) Combined ectopic expression of Pdx1 and Ptf1a/p48 results in the stable conversion of posterior endoderm into endocrine and exocrine pancreatic tissue. Genes Dev 20:1441-1446.
26. Cockell M, Stevenson BJ, Strubin M, Hagenbuchle O, Wellauer PK (1989) Identification of a cell-specific DNA-binding activity that interacts with a transcriptional activator of genes expressed in the acinar pancreas. Mol Cell Biol 9:2464-2476.
27. Jensen J, et al. (2000) Control of endodermal endocrine development by Hes-1. Nat Genet 24:36-44.
28. Habener JF, Kemp DM, Thomas MK (2005) Minireview: Transcriptional regulation in pancreatic development. Endocrinology 146:1025-1034.
29. Apelqvist A, et al. (1999) Notch signaling controls pancreatic cell differentiation. Nature 400:877-881.
30. Wang RN, Kloppel G, Bouwens L (1995) Duct- to islet-cell differentiation and islet growth in the pancreas of duct-ligated adult rats. Diabetologia 38:1405-1411.
31. Tezel E, et al. (2004) REG I as a marker for human pancreatic acinoductular cells. Hepatogastroenterology 51:91-96.
32. Strobel O, et al. (2007) β-Cell transdifferentiation does not contribute to preneoplastic/ metaplastic ductal lesions of the pancreas by genetic lineage tracing in vivo. Proc Natl Acad Sci USA 104:4419-4424.
33. Jensen JN, et al. (2005) Recapitulation of elements of embryonic development in adult mouse pancreatic regeneration. Gastroenterology 128:728-741.
34. Means AL, et al. (2005) Pancreatic epithelial plasticity mediated by acinar cell trans-differentiation and generation of nestin-positive intermediates. Development 132:3767-3776.
35. Schreiber AM, Cai L, Brown DD (2005) Remodeling of the intestine during metamorphosis of Xenopus laevis. Proc Natl Acad Sci USA 102:3720-3725.
36. Rooman I, et al. (2006) Expression of the Notch signaling pathway and effect on exocrine cell proliferation in adult rat pancreas. Am J Pathol 169:1206-1214.
37. Sawey ET, Johnson JA, Crawford HC (2007) Matrix metalloproteinase 7 controls pancreatic acinar cell transdifferentiation by activating the Notch signaling pathway. Proc Natl Acad Sci USA 104:19327-19332.
38. Lardon J, Bouwens L (2005) Metaplasia in the pancreas. Differentiation 73:278-286.
39. Beck CW, Slack JM (1999) Gut-specific expression using mammalian promoters in transgenic Xenopus laevis. Mech Dev 88:221-227.
40. Kruse F, Rose SD, Swift GH, Hammer RE, MacDonald RJ (1993) An endocrine-specific element is an integral component of an exocrine-specific pancreatic enhancer. Genes Dev 7:774-786.
41. Kroll KL, Amaya E (1996) Transgenic Xenopus embryos from sperm nuclear transplantations reveal FGF signaling requirements during gastrulation. Development 122:3173-3183.
42. Huang H, Marsh-Armstrong N, Brown DD (1999) Metamorphosis is inhibited in transgenic Xenopus laevis tadpoles that overexpress type III deiodinase. Proc Natl Acad Sci USA 96:962-967.
43. Smolich BD, Tarkington SK, Saha MS, Stathakis DG, Grainger RM (1993) Characterization of Xenopus laevis γ-crystallin-encoding genes. Gene 128:189-195.
44. Nieuwkoop PD, Faber J (1956) Normal tables of Xenopus laevis (Daudin) (North Holland, Amsterdam).
45. Berry DL, Schwartzman RA, Brown DD (1998) The expression pattern of thyroid hormone response genes in the tadpole tail identifies multiple resorption programs. Dev Biol 203:12-23.