-
1
-
-
0029950724
-
The morphogenesis of the pancreatic mesenchyme is uncoupled from that of the pancreatic epithelium in IPF1/PDX1-deficient mice
-
Ahlgren, U., Jonsson, J., Edlund, H., The morphogenesis of the pancreatic mesenchyme is uncoupled from that of the pancreatic epithelium in IPF1/PDX1-deficient mice. Development 122 (1996), 1409–1416.
-
(1996)
Development
, vol.122
, pp. 1409-1416
-
-
Ahlgren, U.1
Jonsson, J.2
Edlund, H.3
-
2
-
-
0031260579
-
Sonic hedgehog directs specialised mesoderm differentiation in the intestine and pancreas
-
Apelqvist, A., Ahlgren, U., Edlund, H., Sonic hedgehog directs specialised mesoderm differentiation in the intestine and pancreas. Curr. Biol. 7 (1997), 801–804.
-
(1997)
Curr. Biol.
, vol.7
, pp. 801-804
-
-
Apelqvist, A.1
Ahlgren, U.2
Edlund, H.3
-
3
-
-
0033606972
-
Notch signalling controls pancreatic cell differentiation
-
Apelqvist, A., Li, H., Sommer, L., Beatus, P., Anderson, D.J., Honjo, T., Hrabe de Angelis, M., Lendahl, U., Edlund, H., Notch signalling controls pancreatic cell differentiation. Nature 400 (1999), 877–881.
-
(1999)
Nature
, vol.400
, pp. 877-881
-
-
Apelqvist, A.1
Li, H.2
Sommer, L.3
Beatus, P.4
Anderson, D.J.5
Honjo, T.6
Hrabe de Angelis, M.7
Lendahl, U.8
Edlund, H.9
-
4
-
-
34248171703
-
Control of beta-cell differentiation by the pancreatic mesenchyme
-
Attali, M., Stetsyuk, V., Basmaciogullari, A., Aiello, V., Zanta-Boussif, M.A., Duvillie, B., Scharfmann, R., Control of beta-cell differentiation by the pancreatic mesenchyme. Diabetes 56 (2007), 1248–1258.
-
(2007)
Diabetes
, vol.56
, pp. 1248-1258
-
-
Attali, M.1
Stetsyuk, V.2
Basmaciogullari, A.3
Aiello, V.4
Zanta-Boussif, M.A.5
Duvillie, B.6
Scharfmann, R.7
-
5
-
-
65249128642
-
Notch signaling as gatekeeper of rat acinar-to-beta-cell conversion in vitro
-
Baeyens, L., Bonne, S., Bos, T., Rooman, I., Peleman, C., Lahoutte, T., German, M., Heimberg, H., Bouwens, L., Notch signaling as gatekeeper of rat acinar-to-beta-cell conversion in vitro. Gastroenterology 136 (2009), 1750–1760.
-
(2009)
Gastroenterology
, vol.136
, pp. 1750-1760
-
-
Baeyens, L.1
Bonne, S.2
Bos, T.3
Rooman, I.4
Peleman, C.5
Lahoutte, T.6
German, M.7
Heimberg, H.8
Bouwens, L.9
-
6
-
-
52749088737
-
HES-1 is involved in adaptation of adult human beta-cells to proliferation in vitro
-
Bar, Y., Russ, H.A., Knoller, S., Ouziel-Yahalom, L., Efrat, S., HES-1 is involved in adaptation of adult human beta-cells to proliferation in vitro. Diabetes 57 (2008), 2413–2420.
-
(2008)
Diabetes
, vol.57
, pp. 2413-2420
-
-
Bar, Y.1
Russ, H.A.2
Knoller, S.3
Ouziel-Yahalom, L.4
Efrat, S.5
-
7
-
-
0041856137
-
Functional, persistent, and extended liver to pancreas transdifferentiation
-
Ber, I., Shternhall, K., Perl, S., Ohanuna, Z., Goldberg, I., Barshack, I., Benvenisti-Zarum, L., Meivar-Levy, I., Ferber, S., Functional, persistent, and extended liver to pancreas transdifferentiation. J. Biol. Chem. 278 (2003), 31950–31957.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 31950-31957
-
-
Ber, I.1
Shternhall, K.2
Perl, S.3
Ohanuna, Z.4
Goldberg, I.5
Barshack, I.6
Benvenisti-Zarum, L.7
Meivar-Levy, I.8
Ferber, S.9
-
8
-
-
33645236232
-
PTF1 is an organ-specific and Notch-independent basic helix-loop-helix complex containing the mammalian Suppressor of Hairless (RBP-J) or its paralogue, RBP-L
-
Beres, T.M., Masui, T., Swift, G.H., Shi, L., Henke, R.M., MacDonald, R.J., PTF1 is an organ-specific and Notch-independent basic helix-loop-helix complex containing the mammalian Suppressor of Hairless (RBP-J) or its paralogue, RBP-L. Mol. Cell. Biol. 26 (2006), 117–130.
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 117-130
-
-
Beres, T.M.1
Masui, T.2
Swift, G.H.3
Shi, L.4
Henke, R.M.5
MacDonald, R.J.6
-
9
-
-
0035694459
-
Fgf10 is essential for maintaining the proliferative capacity of epithelial progenitor cells during early pancreatic organogenesis
-
Bhushan, A., Itoh, N., Kato, S., Thiery, J.P., Czernichow, P., Bellusci, S., Scharfmann, R., Fgf10 is essential for maintaining the proliferative capacity of epithelial progenitor cells during early pancreatic organogenesis. Development 128 (2001), 5109–5117.
-
(2001)
Development
, vol.128
, pp. 5109-5117
-
-
Bhushan, A.1
Itoh, N.2
Kato, S.3
Thiery, J.P.4
Czernichow, P.5
Bellusci, S.6
Scharfmann, R.7
-
10
-
-
0034608816
-
In vitro cultivation of human islets from expanded ductal tissue
-
Bonner-Weir, S., Taneja, M., Weir, G.C., Tatarkiewicz, K., Song, K.H., Sharma, A., O'Neil, J.J., In vitro cultivation of human islets from expanded ductal tissue. Proc. Natl. Acad. Sci. USA 97 (2000), 7999–8004.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 7999-8004
-
-
Bonner-Weir, S.1
Taneja, M.2
Weir, G.C.3
Tatarkiewicz, K.4
Song, K.H.5
Sharma, A.6
O'Neil, J.J.7
-
11
-
-
62949210744
-
Small molecules efficiently direct endodermal differentiation of mouse and human embryonic stem cells
-
Borowiak, M., Maehr, R., Chen, S., Chen, A.E., Tang, W., Fox, J.L., Schreiber, S.L., Melton, D.A., Small molecules efficiently direct endodermal differentiation of mouse and human embryonic stem cells. Cell Stem Cell 4 (2009), 348–358.
-
(2009)
Cell Stem Cell
, vol.4
, pp. 348-358
-
-
Borowiak, M.1
Maehr, R.2
Chen, S.3
Chen, A.E.4
Tang, W.5
Fox, J.L.6
Schreiber, S.L.7
Melton, D.A.8
-
12
-
-
1342263517
-
Hex homeobox gene-dependent tissue positioning is required for organogenesis of the ventral pancreas
-
Bort, R., Martinez-Barbera, J.P., Beddington, R.S., Zaret, K.S., Hex homeobox gene-dependent tissue positioning is required for organogenesis of the ventral pancreas. Development 131 (2004), 797–806.
-
(2004)
Development
, vol.131
, pp. 797-806
-
-
Bort, R.1
Martinez-Barbera, J.P.2
Beddington, R.S.3
Zaret, K.S.4
-
13
-
-
33845540482
-
Pancreatic islet production of vascular endothelial growth factor—a is essential for islet vascularization, revascularization, and function
-
Brissova, M., Shostak, A., Shiota, M., Wiebe, P.O., Poffenberger, G., Kantz, J., Chen, Z., Carr, C., Jerome, W.G., Chen, J., et al. Pancreatic islet production of vascular endothelial growth factor—a is essential for islet vascularization, revascularization, and function. Diabetes 55 (2006), 2974–2985.
-
(2006)
Diabetes
, vol.55
, pp. 2974-2985
-
-
Brissova, M.1
Shostak, A.2
Shiota, M.3
Wiebe, P.O.4
Poffenberger, G.5
Kantz, J.6
Chen, Z.7
Carr, C.8
Jerome, W.G.9
Chen, J.10
-
14
-
-
42449086826
-
Regulated beta-cell regeneration in the adult mouse pancreas
-
Cano, D.A., Rulifson, I.C., Heiser, P.W., Swigart, L.B., Pelengaris, S., German, M., Evan, G.I., Bluestone, J.A., Hebrok, M., Regulated beta-cell regeneration in the adult mouse pancreas. Diabetes 57 (2008), 958–966.
-
(2008)
Diabetes
, vol.57
, pp. 958-966
-
-
Cano, D.A.1
Rulifson, I.C.2
Heiser, P.W.3
Swigart, L.B.4
Pelengaris, S.5
German, M.6
Evan, G.I.7
Bluestone, J.A.8
Hebrok, M.9
-
15
-
-
64049085356
-
Acute pancreatitis markedly accelerates pancreatic cancer progression in mice expressing oncogenic Kras
-
Carriere, C., Young, A.L., Gunn, J.R., Longnecker, D.S., Korc, M., Acute pancreatitis markedly accelerates pancreatic cancer progression in mice expressing oncogenic Kras. Biochem. Biophys. Res. Commun. 82 (2009), 561–565.
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.82
, pp. 561-565
-
-
Carriere, C.1
Young, A.L.2
Gunn, J.R.3
Longnecker, D.S.4
Korc, M.5
-
16
-
-
65249093055
-
Polycomb protein Ezh2 regulates pancreatic beta-cell Ink4a/Arf expression and regeneration in diabetes mellitus
-
Chen, H., Gu, X., Su, I.H., Bottino, R., Contreras, J.L., Tarakhovsky, A., Kim, S.K., Polycomb protein Ezh2 regulates pancreatic beta-cell Ink4a/Arf expression and regeneration in diabetes mellitus. Genes Dev. 23 (2009), 975–985.
-
(2009)
Genes Dev.
, vol.23
, pp. 975-985
-
-
Chen, H.1
Gu, X.2
Su, I.H.3
Bottino, R.4
Contreras, J.L.5
Tarakhovsky, A.6
Kim, S.K.7
-
17
-
-
55549098894
-
Bmp2 signaling regulates the hepatic versus pancreatic fate decision
-
Chung, W.S., Shin, C.H., Stainier, D.Y., Bmp2 signaling regulates the hepatic versus pancreatic fate decision. Dev. Cell 15 (2008), 738–748.
-
(2008)
Dev. Cell
, vol.15
, pp. 738-748
-
-
Chung, W.S.1
Shin, C.H.2
Stainier, D.Y.3
-
18
-
-
33744920617
-
Molecular control of cell cycle progression in the pancreatic beta-cell
-
Cozar-Castellano, I., Fiaschi-Taesch, N., Bigatel, T.A., Takane, K.K., Garcia-Ocaña, A., Vasavada, R., Stewart, A.F., Molecular control of cell cycle progression in the pancreatic beta-cell. Endocr. Rev. 27 (2006), 356–370.
-
(2006)
Endocr. Rev.
, vol.27
, pp. 356-370
-
-
Cozar-Castellano, I.1
Fiaschi-Taesch, N.2
Bigatel, T.A.3
Takane, K.K.4
Garcia-Ocaña, A.5
Vasavada, R.6
Stewart, A.F.7
-
19
-
-
28644448149
-
Efficient differentiation of human embryonic stem cells to definitive endoderm
-
D'Amour, K.A., Agulnick, A.D., Eliazer, S., Kelly, O.G., Kroon, E., Baetge, E.E., Efficient differentiation of human embryonic stem cells to definitive endoderm. Nat. Biotechnol. 23 (2005), 1534–1541.
-
(2005)
Nat. Biotechnol.
, vol.23
, pp. 1534-1541
-
-
D'Amour, K.A.1
Agulnick, A.D.2
Eliazer, S.3
Kelly, O.G.4
Kroon, E.5
Baetge, E.E.6
-
20
-
-
33750846133
-
Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells
-
D'Amour, K.A., Bang, A.G., Eliazer, S., Kelly, O.G., Agulnick, A.D., Smart, N.G., Moorman, M.A., Kroon, E., Carpenter, M.K., Baetge, E.E., Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells. Nat. Biotechnol. 24 (2006), 1392–1401.
-
(2006)
Nat. Biotechnol.
, vol.24
, pp. 1392-1401
-
-
D'Amour, K.A.1
Bang, A.G.2
Eliazer, S.3
Kelly, O.G.4
Agulnick, A.D.5
Smart, N.G.6
Moorman, M.A.7
Kroon, E.8
Carpenter, M.K.9
Baetge, E.E.10
-
21
-
-
64649105053
-
TCF7L2 regulates late events in insulin secretion from pancreatic islet beta-cells
-
da Silva Xavier, G., Loder, M.K., McDonald, A., Tarasov, A.I., Carzaniga, R., Kronenberger, K., Barg, S., Rutter, G.A., TCF7L2 regulates late events in insulin secretion from pancreatic islet beta-cells. Diabetes 58 (2009), 894–905.
-
(2009)
Diabetes
, vol.58
, pp. 894-905
-
-
da Silva Xavier, G.1
Loder, M.K.2
McDonald, A.3
Tarasov, A.I.4
Carzaniga, R.5
Kronenberger, K.6
Barg, S.7
Rutter, G.A.8
-
22
-
-
57749116315
-
Notch and Kras reprogram pancreatic acinar cells to ductal intraepithelial neoplasia
-
De La O, J.-P., Emerson, L.L., Goodman, J.L., Froebe, S.C., Illum, B.E., Curtis, A.B., Murtaugh, L.C., Notch and Kras reprogram pancreatic acinar cells to ductal intraepithelial neoplasia. Proc. Natl. Acad. Sci. USA 105 (2008), 18907–18912.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 18907-18912
-
-
De La O, J.-P.1
Emerson, L.L.2
Goodman, J.L.3
Froebe, S.C.4
Illum, B.E.5
Curtis, A.B.6
Murtaugh, L.C.7
-
23
-
-
34147190365
-
Preexisting pancreatic acinar cells contribute to acinar cell, but not islet beta cell, regeneration
-
Desai, B.M., Oliver-Krasinski, J., De Leon, D.D., Farzad, C., Hong, N., Leach, S.D., Stoffers, D.A., Preexisting pancreatic acinar cells contribute to acinar cell, but not islet beta cell, regeneration. J. Clin. Invest. 117 (2007), 971–977.
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 971-977
-
-
Desai, B.M.1
Oliver-Krasinski, J.2
De Leon, D.D.3
Farzad, C.4
Hong, N.5
Leach, S.D.6
Stoffers, D.A.7
-
24
-
-
0035072545
-
A bipotential precursor population for pancreas and liver within the embryonic endoderm
-
Deutsch, G., Jung, J., Zheng, M., Lóra, J., Zaret, K.S., A bipotential precursor population for pancreas and liver within the embryonic endoderm. Development 128 (2001), 871–881.
-
(2001)
Development
, vol.128
, pp. 871-881
-
-
Deutsch, G.1
Jung, J.2
Zheng, M.3
Lóra, J.4
Zaret, K.S.5
-
25
-
-
65249121864
-
Bmi-1 regulates the Ink4a/Arf locus to control pancreatic beta-cell proliferation
-
Dhawan, S., Tschen, S.I., Bhushan, A., Bmi-1 regulates the Ink4a/Arf locus to control pancreatic beta-cell proliferation. Genes Dev. 23 (2009), 906–911.
-
(2009)
Genes Dev.
, vol.23
, pp. 906-911
-
-
Dhawan, S.1
Tschen, S.I.2
Bhushan, A.3
-
26
-
-
2342510386
-
Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation
-
Dor, Y., Brown, J., Martinez, O.I., Melton, D.A., Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation. Nature 429 (2004), 41–46.
-
(2004)
Nature
, vol.429
, pp. 41-46
-
-
Dor, Y.1
Brown, J.2
Martinez, O.I.3
Melton, D.A.4
-
27
-
-
33846964532
-
Beta cells occur naturally in extrahepatic bile ducts of mice
-
Dutton, J.R., Chillingworth, N.L., Eberhard, D., Brannon, C.R., Hornsey, M.A., Tosh, D., Slack, J.M., Beta cells occur naturally in extrahepatic bile ducts of mice. J. Cell Sci. 120 (2007), 239–245.
-
(2007)
J. Cell Sci.
, vol.120
, pp. 239-245
-
-
Dutton, J.R.1
Chillingworth, N.L.2
Eberhard, D.3
Brannon, C.R.4
Hornsey, M.A.5
Tosh, D.6
Slack, J.M.7
-
28
-
-
33644774753
-
The mesenchyme controls the timing of pancreatic beta-cell differentiation
-
Duvillié, B., Attali, M., Bounacer, A., Ravassard, P., Basmaciogullari, A., Scharfmann, R., The mesenchyme controls the timing of pancreatic beta-cell differentiation. Diabetes 55 (2006), 582–589.
-
(2006)
Diabetes
, vol.55
, pp. 582-589
-
-
Duvillié, B.1
Attali, M.2
Bounacer, A.3
Ravassard, P.4
Basmaciogullari, A.5
Scharfmann, R.6
-
29
-
-
55549101898
-
Origin of pancreatic endocrine cells from biliary duct epithelium
-
Eberhard, D., Tosh, D., Slack, J.M., Origin of pancreatic endocrine cells from biliary duct epithelium. Cell. Mol. Life Sci. 65 (2008), 3467–3480.
-
(2008)
Cell. Mol. Life Sci.
, vol.65
, pp. 3467-3480
-
-
Eberhard, D.1
Tosh, D.2
Slack, J.M.3
-
30
-
-
16844375322
-
Vascular function and sphingosine-1-phosphate regulate development of the dorsal pancreatic mesenchyme
-
Edsbagge, J., Johansson, J.K., Esni, F., Luo, Y., Radice, G.L., Semb, H., Vascular function and sphingosine-1-phosphate regulate development of the dorsal pancreatic mesenchyme. Development 132 (2005), 1085–1092.
-
(2005)
Development
, vol.132
, pp. 1085-1092
-
-
Edsbagge, J.1
Johansson, J.K.2
Esni, F.3
Luo, Y.4
Radice, G.L.5
Semb, H.6
-
31
-
-
4444277786
-
Notch inhibits Ptf1 function and acinar cell differentiation in developing mouse and zebrafish pancreas
-
Esni, F., Ghosh, B., Biankin, A.V., Lin, J.W., Albert, M.A., Yu, X., MacDonald, R.J., Civin, C.I., Real, F.X., Pack, M.A., et al. Notch inhibits Ptf1 function and acinar cell differentiation in developing mouse and zebrafish pancreas. Development 131 (2004), 4213–4224.
-
(2004)
Development
, vol.131
, pp. 4213-4224
-
-
Esni, F.1
Ghosh, B.2
Biankin, A.V.3
Lin, J.W.4
Albert, M.A.5
Yu, X.6
MacDonald, R.J.7
Civin, C.I.8
Real, F.X.9
Pack, M.A.10
-
32
-
-
0034068602
-
Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia
-
Ferber, S., Halkin, A., Cohen, H., Ber, I., Einav, Y., Goldberg, I., Barshack, I., Seijffers, R., Kopolovic, J., Kaiser, N., Karasik, A., Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia. Nat. Med. 6 (2000), 568–572.
-
(2000)
Nat. Med.
, vol.6
, pp. 568-572
-
-
Ferber, S.1
Halkin, A.2
Cohen, H.3
Ber, I.4
Einav, Y.5
Goldberg, I.6
Barshack, I.7
Seijffers, R.8
Kopolovic, J.9
Kaiser, N.10
Karasik, A.11
-
33
-
-
33745214464
-
Ectopic pancreas formation in Hes1 -knockout mice reveals plasticity of endodermal progenitors of the gut, bile duct, and pancreas
-
Fukuda, A., Kawaguchi, Y., Furuyama, K., Kodama, S., Horiguchi, M., Kuhara, T., Koizumi, M., Boyer, D.F., Fujimoto, K., Doi, R., et al. Ectopic pancreas formation in Hes1 -knockout mice reveals plasticity of endodermal progenitors of the gut, bile duct, and pancreas. J. Clin. Invest. 116 (2006), 1484–1493.
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 1484-1493
-
-
Fukuda, A.1
Kawaguchi, Y.2
Furuyama, K.3
Kodama, S.4
Horiguchi, M.5
Kuhara, T.6
Koizumi, M.7
Boyer, D.F.8
Fujimoto, K.9
Doi, R.10
-
34
-
-
0043268785
-
Characterization of endocrine progenitor cells and critical factors for their differentiation in human adult pancreatic cell culture
-
Gao, R., Ustinov, J., Pulkkinen, M.A., Lundin, K., Korsgren, O., Otonkoski, T., Characterization of endocrine progenitor cells and critical factors for their differentiation in human adult pancreatic cell culture. Diabetes 52 (2003), 2007–2015.
-
(2003)
Diabetes
, vol.52
, pp. 2007-2015
-
-
Gao, R.1
Ustinov, J.2
Pulkkinen, M.A.3
Lundin, K.4
Korsgren, O.5
Otonkoski, T.6
-
35
-
-
58049204234
-
Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development
-
Gao, N., LeLay, J., Vatamaniuk, M.Z., Rieck, S., Friedman, J.R., Kaestner, K.H., Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development. Genes Dev. 22 (2008), 3435–3448.
-
(2008)
Genes Dev.
, vol.22
, pp. 3435-3448
-
-
Gao, N.1
LeLay, J.2
Vatamaniuk, M.Z.3
Rieck, S.4
Friedman, J.R.5
Kaestner, K.H.6
-
36
-
-
0033954474
-
Hepatocyte growth factor overexpression in the islet of transgenic mice increases beta cell proliferation, enhances islet mass, and induces mild hypoglycemia
-
Garcia-Ocaña, A., Takane, K.K., Syed, M.A., Philbrick, W.M., Vasavada, R.C., Stewart, A.F., Hepatocyte growth factor overexpression in the islet of transgenic mice increases beta cell proliferation, enhances islet mass, and induces mild hypoglycemia. J. Biol. Chem. 275 (2000), 1226–1232.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 1226-1232
-
-
Garcia-Ocaña, A.1
Takane, K.K.2
Syed, M.A.3
Philbrick, W.M.4
Vasavada, R.C.5
Stewart, A.F.6
-
37
-
-
4444235281
-
Proendocrine genes coordinate the pancreatic islet differentiation program in vitro
-
Gasa, R., Mrejen, C., Leachman, N., Otten, M., Barnes, M., Wang, J., Chakrabarti, S., Mirmira, R., German, M., Proendocrine genes coordinate the pancreatic islet differentiation program in vitro. Proc. Natl. Acad. Sci. USA 101 (2004), 13245–13250.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 13245-13250
-
-
Gasa, R.1
Mrejen, C.2
Leachman, N.3
Otten, M.4
Barnes, M.5
Wang, J.6
Chakrabarti, S.7
Mirmira, R.8
German, M.9
-
38
-
-
9644266753
-
Beta cell replication is the primary mechanism for maintaining postnatal beta cell mass
-
Georgia, S., Bhushan, A., Beta cell replication is the primary mechanism for maintaining postnatal beta cell mass. J. Clin. Invest. 114 (2004), 963–968.
-
(2004)
J. Clin. Invest.
, vol.114
, pp. 963-968
-
-
Georgia, S.1
Bhushan, A.2
-
39
-
-
33845513370
-
p27 Regulates the transition of beta-cells from quiescence to proliferation
-
Georgia, S., Bhushan, A., p27 Regulates the transition of beta-cells from quiescence to proliferation. Diabetes 55 (2006), 2950–2956.
-
(2006)
Diabetes
, vol.55
, pp. 2950-2956
-
-
Georgia, S.1
Bhushan, A.2
-
40
-
-
58549093915
-
Developmental biology of the pancreas: a comprehensive review
-
Gittes, G.K., Developmental biology of the pancreas: a comprehensive review. Dev. Biol. 326 (2009), 4–35.
-
(2009)
Dev. Biol.
, vol.326
, pp. 4-35
-
-
Gittes, G.K.1
-
41
-
-
0030041280
-
Lineage-specific morphogenesis in the developing pancreas: role of mesenchymal factors
-
Gittes, G.K., Galante, P.E., Hanahan, D., Rutter, W.J., Debase, H.T., Lineage-specific morphogenesis in the developing pancreas: role of mesenchymal factors. Development 122 (1996), 439–447.
-
(1996)
Development
, vol.122
, pp. 439-447
-
-
Gittes, G.K.1
Galante, P.E.2
Hanahan, D.3
Rutter, W.J.4
Debase, H.T.5
-
42
-
-
0034652287
-
neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas
-
Gradwohl, G., Dierich, A., LeMeur, M., Guillemot, F., neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas. Proc. Natl. Acad. Sci. USA 97 (2000), 1607–1611.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 1607-1611
-
-
Gradwohl, G.1
Dierich, A.2
LeMeur, M.3
Guillemot, F.4
-
43
-
-
32544451924
-
Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes
-
Grant, S.F., Thorleifsson, G., Reynisdottir, I., Benediktsson, R., Manolescu, A., Sainz, J., Helgason, A., Stefansson, H., Emilsson, V., Helgadottir, A., et al. Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes. Nat. Genet. 38 (2006), 320–323.
-
(2006)
Nat. Genet.
, vol.38
, pp. 320-323
-
-
Grant, S.F.1
Thorleifsson, G.2
Reynisdottir, I.3
Benediktsson, R.4
Manolescu, A.5
Sainz, J.6
Helgason, A.7
Stefansson, H.8
Emilsson, V.9
Helgadottir, A.10
-
44
-
-
0036340074
-
Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors
-
Gu, G., Dubauskaite, J., Melton, D.A., Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors. Development 129 (2002), 2447–2457.
-
(2002)
Development
, vol.129
, pp. 2447-2457
-
-
Gu, G.1
Dubauskaite, J.2
Melton, D.A.3
-
45
-
-
33847419143
-
Chronic pancreatitis is essential for induction of pancreatic ductal adenocarcinoma by K-Ras oncogenes in adult mice
-
Guerra, C., Schuhmacher, A.J., Cañamero, M., Grippo, P.J., Verdaguer, L., Pérez-Gallego, L., Dubus, P., Sandgren, E.P., Barbacid, M., Chronic pancreatitis is essential for induction of pancreatic ductal adenocarcinoma by K-Ras oncogenes in adult mice. Cancer Cell 11 (2007), 291–302.
-
(2007)
Cancer Cell
, vol.11
, pp. 291-302
-
-
Guerra, C.1
Schuhmacher, A.J.2
Cañamero, M.3
Grippo, P.J.4
Verdaguer, L.5
Pérez-Gallego, L.6
Dubus, P.7
Sandgren, E.P.8
Barbacid, M.9
-
46
-
-
34147173677
-
Expansion of adult beta-cell mass in response to increased metabolic demand is dependent on HNF-4alpha
-
Gupta, R.K., Gao, N., Gorski, R.K., White, P., Hardy, O.T., Rafiq, K., Brestelli, J.E., Chen, G., Stoeckert, C.J. Jr., Kaestner, K.H., Expansion of adult beta-cell mass in response to increased metabolic demand is dependent on HNF-4alpha. Genes Dev. 21 (2007), 756–769.
-
(2007)
Genes Dev.
, vol.21
, pp. 756-769
-
-
Gupta, R.K.1
Gao, N.2
Gorski, R.K.3
White, P.4
Hardy, O.T.5
Rafiq, K.6
Brestelli, J.E.7
Chen, G.8
Stoeckert, C.J.9
Kaestner, K.H.10
-
47
-
-
0042665560
-
Activated Notch1 prevents differentiation of pancreatic acinar cells and attenuate endocrine development
-
Hald, J., Hjorth, J.P., German, M.S., Madsen, O.D., Serup, P., Jensen, J., Activated Notch1 prevents differentiation of pancreatic acinar cells and attenuate endocrine development. Dev. Biol. 260 (2003), 426–437.
-
(2003)
Dev. Biol.
, vol.260
, pp. 426-437
-
-
Hald, J.1
Hjorth, J.P.2
German, M.S.3
Madsen, O.D.4
Serup, P.5
Jensen, J.6
-
48
-
-
0141593480
-
Fgf10 maintains notch activation, stimulates proliferation, and blocks differentiation of pancreatic epithelial cells
-
Hart, A., Papadopoulou, S., Edlund, H., Fgf10 maintains notch activation, stimulates proliferation, and blocks differentiation of pancreatic epithelial cells. Dev. Dyn. 228 (2003), 185–193.
-
(2003)
Dev. Dyn.
, vol.228
, pp. 185-193
-
-
Hart, A.1
Papadopoulou, S.2
Edlund, H.3
-
49
-
-
2642589990
-
Notochord repression of endodermal Sonic hedgehog permits pancreas development
-
Hebrok, M., Kim, S.K., Melton, D.A., Notochord repression of endodermal Sonic hedgehog permits pancreas development. Genes Dev. 12 (1998), 1705–1713.
-
(1998)
Genes Dev.
, vol.12
, pp. 1705-1713
-
-
Hebrok, M.1
Kim, S.K.2
Melton, D.A.3
-
50
-
-
0033636981
-
Regulation of pancreas development by hedgehog signaling
-
Hebrok, M., Kim, S.K., St Jacques, B., McMahon, A.P., Melton, D.A., Regulation of pancreas development by hedgehog signaling. Development 127 (2000), 4905–4913.
-
(2000)
Development
, vol.127
, pp. 4905-4913
-
-
Hebrok, M.1
Kim, S.K.2
St Jacques, B.3
McMahon, A.P.4
Melton, D.A.5
-
51
-
-
33745084564
-
Stabilization of beta-catenin impacts pancreas growth
-
Heiser, P.W., Lau, J., Taketo, M.M., Herrera, P.L., Hebrok, M., Stabilization of beta-catenin impacts pancreas growth. Development 133 (2006), 2023–2032.
-
(2006)
Development
, vol.133
, pp. 2023-2032
-
-
Heiser, P.W.1
Lau, J.2
Taketo, M.M.3
Herrera, P.L.4
Hebrok, M.5
-
52
-
-
0036842027
-
Expression patterns of Wnts, Frizzleds, sFRPs, and misexpression in transgenic mice suggesting a role for Wnts in pancreas and foregut pattern formation
-
Heller, R.S., Dichmann, D.S., Jensen, J., Miller, C., Wong, G., Madsen, O.D., Serup, P., Expression patterns of Wnts, Frizzleds, sFRPs, and misexpression in transgenic mice suggesting a role for Wnts in pancreas and foregut pattern formation. Dev. Dyn. 225 (2002), 260–270.
-
(2002)
Dev. Dyn.
, vol.225
, pp. 260-270
-
-
Heller, R.S.1
Dichmann, D.S.2
Jensen, J.3
Miller, C.4
Wong, G.5
Madsen, O.D.6
Serup, P.7
-
53
-
-
0037191099
-
Recapitulation of embryonic neuroendocrine differentiation in adult human pancreatic duct cells expressing neurogenin 3
-
Heremans, Y., Van De Casteele, M., Veld, P., Gradwohl, G., Serup, P., Madsen, O., Pipeleers, D., Heimberg, H., Recapitulation of embryonic neuroendocrine differentiation in adult human pancreatic duct cells expressing neurogenin 3. J. Cell Biol. 159 (2002), 303–312.
-
(2002)
J. Cell Biol.
, vol.159
, pp. 303-312
-
-
Heremans, Y.1
Van De Casteele, M.2
Veld, P.3
Gradwohl, G.4
Serup, P.5
Madsen, O.6
Pipeleers, D.7
Heimberg, H.8
-
54
-
-
58149378342
-
Carbonic anhydrase II-positive pancreatic cells are progenitors for both endocrine and exocrine pancreas after birth
-
Inada, A., Nienaber, C., Katsuta, H., Fujitani, Y., Levine, J., Morita, R., Sharma, A., Bonner-Weir, S., Carbonic anhydrase II-positive pancreatic cells are progenitors for both endocrine and exocrine pancreas after birth. Proc. Natl. Acad. Sci. USA 105 (2008), 19915–19919.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 19915-19919
-
-
Inada, A.1
Nienaber, C.2
Katsuta, H.3
Fujitani, Y.4
Levine, J.5
Morita, R.6
Sharma, A.7
Bonner-Weir, S.8
-
55
-
-
30544438811
-
An endothelial-mesenchymal relay pathway regulates early phases of pancreas development
-
Jacquemin, P., Yoshitomi, H., Kashima, Y., Rousseau, G.G., Lemaigre, F.P., Zaret, K.S., An endothelial-mesenchymal relay pathway regulates early phases of pancreas development. Dev. Biol. 290 (2006), 189–199.
-
(2006)
Dev. Biol.
, vol.290
, pp. 189-199
-
-
Jacquemin, P.1
Yoshitomi, H.2
Kashima, Y.3
Rousseau, G.G.4
Lemaigre, F.P.5
Zaret, K.S.6
-
56
-
-
67650874081
-
Cancer statistics, 2009
-
Jemal, A., Siegel, R., Ward, E., Hao, Y., Xu, J., Thun, M.J., Cancer statistics, 2009. CA Cancer J. Clin. 59 (2009), 225–249.
-
(2009)
CA Cancer J. Clin.
, vol.59
, pp. 225-249
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Hao, Y.4
Xu, J.5
Thun, M.J.6
-
57
-
-
18544404101
-
Control of endodermal endocrine development by Hes-1
-
Jensen, J., Pedersen, E.E., Galante, P., Hald, J., Heller, R.S., Ishibashi, M., Kageyama, R., Guillemot, F., Serup, P., Madsen, O.D., Control of endodermal endocrine development by Hes-1. Nat. Genet. 24 (2000), 36–44.
-
(2000)
Nat. Genet.
, vol.24
, pp. 36-44
-
-
Jensen, J.1
Pedersen, E.E.2
Galante, P.3
Hald, J.4
Heller, R.S.5
Ishibashi, M.6
Kageyama, R.7
Guillemot, F.8
Serup, P.9
Madsen, O.D.10
-
58
-
-
15744400264
-
Recapitulation of elements of embryonic development in adult mouse pancreatic regeneration
-
Jensen, J.N., Cameron, E., Garay, M.V., Starkey, T.W., Gianani, R., Jensen, J., Recapitulation of elements of embryonic development in adult mouse pancreatic regeneration. Gastroenterology 128 (2005), 728–741.
-
(2005)
Gastroenterology
, vol.128
, pp. 728-741
-
-
Jensen, J.N.1
Cameron, E.2
Garay, M.V.3
Starkey, T.W.4
Gianani, R.5
Jensen, J.6
-
59
-
-
33847217554
-
Temporal control of neurogenin3 activity in pancreas progenitors reveals competence windows for the generation of different endocrine cell types
-
Johansson, K.A., Dursun, U., Jordan, N., Gu, G., Beermann, F., Gradwohl, G., Grapin-Botton, A., Temporal control of neurogenin3 activity in pancreas progenitors reveals competence windows for the generation of different endocrine cell types. Dev. Cell 12 (2007), 457–465.
-
(2007)
Dev. Cell
, vol.12
, pp. 457-465
-
-
Johansson, K.A.1
Dursun, U.2
Jordan, N.3
Gu, G.4
Beermann, F.5
Gradwohl, G.6
Grapin-Botton, A.7
-
60
-
-
0028149890
-
Insulin-promoter-factor 1 is required for pancreas development in mice
-
Jonsson, J., Carlsson, L., Edlund, T., Edlund, H., Insulin-promoter-factor 1 is required for pancreas development in mice. Nature 371 (1994), 606–609.
-
(1994)
Nature
, vol.371
, pp. 606-609
-
-
Jonsson, J.1
Carlsson, L.2
Edlund, T.3
Edlund, H.4
-
61
-
-
15944417831
-
PDX-1/VP16 fusion protein, together with NeuroD or Ngn3, markedly induces insulin gene transcription and ameliorates glucose tolerance
-
Kaneto, H., Nakatani, Y., Miyatsuka, T., Matsuoka, T.A., Matsuhisa, M., Hori, M., Yamasaki, Y., PDX-1/VP16 fusion protein, together with NeuroD or Ngn3, markedly induces insulin gene transcription and ameliorates glucose tolerance. Diabetes 54 (2005), 1009–1022.
-
(2005)
Diabetes
, vol.54
, pp. 1009-1022
-
-
Kaneto, H.1
Nakatani, Y.2
Miyatsuka, T.3
Matsuoka, T.A.4
Matsuhisa, M.5
Hori, M.6
Yamasaki, Y.7
-
62
-
-
38449099624
-
Menin controls growth of pancreatic beta-cells in pregnant mice and promotes gestational diabetes mellitus
-
Karnik, S.K., Chen, H., McLean, G.W., Heit, J.J., Gu, X., Zhang, A.Y., Fontaine, M., Yen, M.H., Kim, S.K., Menin controls growth of pancreatic beta-cells in pregnant mice and promotes gestational diabetes mellitus. Science 318 (2007), 806–809.
-
(2007)
Science
, vol.318
, pp. 806-809
-
-
Karnik, S.K.1
Chen, H.2
McLean, G.W.3
Heit, J.J.4
Gu, X.5
Zhang, A.Y.6
Fontaine, M.7
Yen, M.H.8
Kim, S.K.9
-
63
-
-
0036730427
-
The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors
-
Kawaguchi, Y., Cooper, B., Gannon, M., Ray, M., MacDonald, R.J., Wright, C.V., The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors. Nat. Genet. 32 (2002), 128–134.
-
(2002)
Nat. Genet.
, vol.32
, pp. 128-134
-
-
Kawaguchi, Y.1
Cooper, B.2
Gannon, M.3
Ray, M.4
MacDonald, R.J.5
Wright, C.V.6
-
64
-
-
0032573227
-
Pancreas development is promoted by cyclopamine, a hedgehog signaling inhibitor
-
Kim, S.K., Melton, D.A., Pancreas development is promoted by cyclopamine, a hedgehog signaling inhibitor. Proc. Natl. Acad. Sci. USA 95 (1998), 13036–13041.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 13036-13041
-
-
Kim, S.K.1
Melton, D.A.2
-
65
-
-
0033869726
-
Activin receptor patterning of foregut organogenesis
-
Kim, S.K., Hebrok, M., Li, E., Oh, S.P., Schrewe, H., Harmon, E.B., Lee, J.S., Melton, D.A., Activin receptor patterning of foregut organogenesis. Genes Dev. 14 (2000), 1866–1871.
-
(2000)
Genes Dev.
, vol.14
, pp. 1866-1871
-
-
Kim, S.K.1
Hebrok, M.2
Li, E.3
Oh, S.P.4
Schrewe, H.5
Harmon, E.B.6
Lee, J.S.7
Melton, D.A.8
-
66
-
-
0038413922
-
NeuroD-betacellulin gene therapy induces islet neogenesis in the liver and reverses diabetes in mice
-
Kojima, H., Fujimiya, M., Matsumura, K., Younan, P., Imaeda, H., Maeda, M., Chan, L., NeuroD-betacellulin gene therapy induces islet neogenesis in the liver and reverses diabetes in mice. Nat. Med. 9 (2003), 596–603.
-
(2003)
Nat. Med.
, vol.9
, pp. 596-603
-
-
Kojima, H.1
Fujimiya, M.2
Matsumura, K.3
Younan, P.4
Imaeda, H.5
Maeda, M.6
Chan, L.7
-
67
-
-
0032417268
-
The bHLH protein PTF1-p48 is essential for the formation of the exocrine and the correct spatial organization of the endocrine pancreas
-
Krapp, A., Knöfler, M., Ledermann, B., Bürki, K., Berney, C., Zoerkler, N., Hagenbüchle, O., Wellauer, P.K., The bHLH protein PTF1-p48 is essential for the formation of the exocrine and the correct spatial organization of the endocrine pancreas. Genes Dev. 12 (1998), 3752–3763.
-
(1998)
Genes Dev.
, vol.12
, pp. 3752-3763
-
-
Krapp, A.1
Knöfler, M.2
Ledermann, B.3
Bürki, K.4
Berney, C.5
Zoerkler, N.6
Hagenbüchle, O.7
Wellauer, P.K.8
-
68
-
-
33749187810
-
p16INK4a induces an age-dependent decline in islet regenerative potential
-
Krishnamurthy, J., Ramsey, M.R., Ligon, K.L., Torrice, C., Koh, A., Bonner-Weir, S., Sharpless, N.E., p16INK4a induces an age-dependent decline in islet regenerative potential. Nature 443 (2006), 453–457.
-
(2006)
Nature
, vol.443
, pp. 453-457
-
-
Krishnamurthy, J.1
Ramsey, M.R.2
Ligon, K.L.3
Torrice, C.4
Koh, A.5
Bonner-Weir, S.6
Sharpless, N.E.7
-
69
-
-
41849151748
-
Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo
-
Kroon, E., Martinson, L.A., Kadoya, K., Bang, A.G., Kelly, O.G., Eliazer, S., Young, H., Richardson, M., Smart, N.G., Cunningham, J., et al. Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo. Nat. Biotechnol. 26 (2008), 443–452.
-
(2008)
Nat. Biotechnol.
, vol.26
, pp. 443-452
-
-
Kroon, E.1
Martinson, L.A.2
Kadoya, K.3
Bang, A.G.4
Kelly, O.G.5
Eliazer, S.6
Young, H.7
Richardson, M.8
Smart, N.G.9
Cunningham, J.10
-
70
-
-
0037706944
-
Signals from lateral plate mesoderm instruct endoderm toward a pancreatic fate
-
Kumar, M., Jordan, N., Melton, D., Grapin-Botton, A., Signals from lateral plate mesoderm instruct endoderm toward a pancreatic fate. Dev. Biol. 259 (2003), 109–122.
-
(2003)
Dev. Biol.
, vol.259
, pp. 109-122
-
-
Kumar, M.1
Jordan, N.2
Melton, D.3
Grapin-Botton, A.4
-
71
-
-
17644387563
-
Cyclins D2 and D1 are essential for postnatal pancreatic beta-cell growth
-
Kushner, J.A., Ciemerych, M.A., Sicinska, E., Wartschow, L.M., Teta, M., Long, S.Y., Sicinski, P., White, M.F., Cyclins D2 and D1 are essential for postnatal pancreatic beta-cell growth. Mol. Cell. Biol. 25 (2005), 3752–3762.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 3752-3762
-
-
Kushner, J.A.1
Ciemerych, M.A.2
Sicinska, E.3
Wartschow, L.M.4
Teta, M.5
Long, S.Y.6
Sicinski, P.7
White, M.F.8
-
72
-
-
0034212390
-
Notch gene expression during pancreatic organogenesis
-
Lammert, E., Brown, J., Melton, D.A., Notch gene expression during pancreatic organogenesis. Mech. Dev. 94 (2000), 199–203.
-
(2000)
Mech. Dev.
, vol.94
, pp. 199-203
-
-
Lammert, E.1
Brown, J.2
Melton, D.A.3
-
73
-
-
0035913986
-
Induction of pancreatic differentiation by signals from blood vessels
-
Lammert, E., Cleaver, O., Melton, D., Induction of pancreatic differentiation by signals from blood vessels. Science 294 (2001), 564–567.
-
(2001)
Science
, vol.294
, pp. 564-567
-
-
Lammert, E.1
Cleaver, O.2
Melton, D.3
-
74
-
-
0037665295
-
Role of VEGF-A in vascularization of pancreatic islets
-
Lammert, E., Gu, G., McLaughlin, M., Brown, D., Brekken, R., Murtaugh, L.C., Gerber, H.P., Ferrara, N., Melton, D.A., Role of VEGF-A in vascularization of pancreatic islets. Curr. Biol. 13 (2003), 1070–1074.
-
(2003)
Curr. Biol.
, vol.13
, pp. 1070-1074
-
-
Lammert, E.1
Gu, G.2
McLaughlin, M.3
Brown, D.4
Brekken, R.5
Murtaugh, L.C.6
Gerber, H.P.7
Ferrara, N.8
Melton, D.A.9
-
75
-
-
34547525676
-
Sox9 coordinates a transcriptional network in pancreatic progenitor cells
-
Lynn, F.C., Smith, S.B., Wilson, M.E., Yang, K.Y., Nekrep, N., German, M.S., Sox9 coordinates a transcriptional network in pancreatic progenitor cells. Proc. Natl. Acad. Sci. USA 104 (2007), 10500–10505.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 10500-10505
-
-
Lynn, F.C.1
Smith, S.B.2
Wilson, M.E.3
Yang, K.Y.4
Nekrep, N.5
German, M.S.6
-
76
-
-
70349437501
-
Generation of pluripotent stem cells from patients with type 1 diabetes
-
Maehr, R., Chen, S., Snitow, M., Ludwig, T., Yagasaki, L., Goland, R., Leibel, R.L., Melton, D.A., Generation of pluripotent stem cells from patients with type 1 diabetes. Proc. Natl. Acad. Sci. USA 106 (2009), 15768–15773.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 15768-15773
-
-
Maehr, R.1
Chen, S.2
Snitow, M.3
Ludwig, T.4
Yagasaki, L.5
Goland, R.6
Leibel, R.L.7
Melton, D.A.8
-
77
-
-
23944453381
-
Dorsal pancreas agenesis in retinoic acid-deficient Raldh2 mutant mice
-
Martín, M., Gallego-Llamas, J., Ribes, V., Kedinger, M., Niederreither, K., Chambon, P., Dollé, P., Gradwohl, G., Dorsal pancreas agenesis in retinoic acid-deficient Raldh2 mutant mice. Dev. Biol. 284 (2005), 399–411.
-
(2005)
Dev. Biol.
, vol.284
, pp. 399-411
-
-
Martín, M.1
Gallego-Llamas, J.2
Ribes, V.3
Kedinger, M.4
Niederreither, K.5
Chambon, P.6
Dollé, P.7
Gradwohl, G.8
-
78
-
-
0041970072
-
Members of the large Maf transcription family regulate insulin gene transcription in islet beta cells
-
Matsuoka, T.A., Zhao, L., Artner, I., Jarrett, H.W., Friedman, D., Means, A., Stein, R., Members of the large Maf transcription family regulate insulin gene transcription in islet beta cells. Mol. Cell. Biol. 23 (2003), 6049–6062.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 6049-6062
-
-
Matsuoka, T.A.1
Zhao, L.2
Artner, I.3
Jarrett, H.W.4
Friedman, D.5
Means, A.6
Stein, R.7
-
79
-
-
24944441782
-
Pancreatic epithelial plasticity mediated by acinar cell transdifferentiation and generation of nestin-positive intermediates
-
Means, A.L., Meszoely, I.M., Suzuki, K., Miyamoto, Y., Rustgi, A.K., Coffey, R.J. Jr., Wright, C.V., Stoffers, D.A., Leach, S.D., Pancreatic epithelial plasticity mediated by acinar cell transdifferentiation and generation of nestin-positive intermediates. Development 132 (2005), 3767–3776.
-
(2005)
Development
, vol.132
, pp. 3767-3776
-
-
Means, A.L.1
Meszoely, I.M.2
Suzuki, K.3
Miyamoto, Y.4
Rustgi, A.K.5
Coffey, R.J.6
Wright, C.V.7
Stoffers, D.A.8
Leach, S.D.9
-
80
-
-
27244437951
-
Lineage tracing and characterization of insulin-secreting cells generated from adult pancreatic acinar cells
-
Minami, K., Okuno, M., Miyawaki, K., Okumachi, A., Ishizaki, K., Oyama, K., Kawaguchi, M., Ishizuka, N., Iwanaga, T., Seino, S., Lineage tracing and characterization of insulin-secreting cells generated from adult pancreatic acinar cells. Proc. Natl. Acad. Sci. USA 102 (2005), 15116–15121.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 15116-15121
-
-
Minami, K.1
Okuno, M.2
Miyawaki, K.3
Okumachi, A.4
Ishizaki, K.5
Oyama, K.6
Kawaguchi, M.7
Ishizuka, N.8
Iwanaga, T.9
Seino, S.10
-
81
-
-
0031916664
-
Follistatin regulates the relative proportions of endocrine versus exocrine tissue during pancreatic development
-
Miralles, F., Czernichow, P., Scharfmann, R., Follistatin regulates the relative proportions of endocrine versus exocrine tissue during pancreatic development. Development 125 (1998), 1017–1024.
-
(1998)
Development
, vol.125
, pp. 1017-1024
-
-
Miralles, F.1
Czernichow, P.2
Scharfmann, R.3
-
82
-
-
10744223624
-
Notch mediates TGF alpha-induced changes in epithelial differentiation during pancreatic tumorigenesis
-
Miyamoto, Y., Maitra, A., Ghosh, B., Zechner, U., Argani, P., Iacobuzio-Donahue, C.A., Sriuranpong, V., Iso, T., Meszoely, I.M., Wolfe, M.S., et al. Notch mediates TGF alpha-induced changes in epithelial differentiation during pancreatic tumorigenesis. Cancer Cell 3 (2003), 565–576.
-
(2003)
Cancer Cell
, vol.3
, pp. 565-576
-
-
Miyamoto, Y.1
Maitra, A.2
Ghosh, B.3
Zechner, U.4
Argani, P.5
Iacobuzio-Donahue, C.A.6
Sriuranpong, V.7
Iso, T.8
Meszoely, I.M.9
Wolfe, M.S.10
-
83
-
-
0141534119
-
Ectopically expressed PDX-1 in liver initiates endocrine and exocrine pancreas differentiation but causes dysmorphogenesis
-
Miyatsuka, T., Kaneto, H., Kajimoto, Y., Hirota, S., Arakawa, Y., Fujitani, Y., Umayahara, Y., Watada, H., Yamasaki, Y., Magnuson, M.A., et al. Ectopically expressed PDX-1 in liver initiates endocrine and exocrine pancreas differentiation but causes dysmorphogenesis. Biochem. Biophys. Res. Commun. 310 (2003), 1017–1025.
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.310
, pp. 1017-1025
-
-
Miyatsuka, T.1
Kaneto, H.2
Kajimoto, Y.3
Hirota, S.4
Arakawa, Y.5
Fujitani, Y.6
Umayahara, Y.7
Watada, H.8
Yamasaki, Y.9
Magnuson, M.A.10
-
84
-
-
33744813002
-
Persistent expression of PDX-1 in the pancreas causes acinar-to-ductal metaplasia through Stat3 activation
-
Miyatsuka, T., Kaneto, H., Shiraiwa, T., Matsuoka, T.A., Yamamoto, K., Kato, K., Nakamura, Y., Akira, S., Takeda, K., Kajimoto, Y., et al. Persistent expression of PDX-1 in the pancreas causes acinar-to-ductal metaplasia through Stat3 activation. Genes Dev. 20 (2006), 1435–1440.
-
(2006)
Genes Dev.
, vol.20
, pp. 1435-1440
-
-
Miyatsuka, T.1
Kaneto, H.2
Shiraiwa, T.3
Matsuoka, T.A.4
Yamamoto, K.5
Kato, K.6
Nakamura, Y.7
Akira, S.8
Takeda, K.9
Kajimoto, Y.10
-
85
-
-
16244406880
-
Retinoic acid generated by Raldh2 in mesoderm is required for mouse dorsal endodermal pancreas development
-
Molotkov, A., Molotkova, N., Duester, G., Retinoic acid generated by Raldh2 in mesoderm is required for mouse dorsal endodermal pancreas development. Dev. Dyn. 232 (2005), 950–957.
-
(2005)
Dev. Dyn.
, vol.232
, pp. 950-957
-
-
Molotkov, A.1
Molotkova, N.2
Duester, G.3
-
86
-
-
76649105065
-
Beta-catenin blocks Kras-dependent reprogramming of acini into pancreatic cancer precursor lesions in mice
-
Morris, J.P., Cano, D.A., Sekine, S., Wang, S.C., Hebrok, M., Beta-catenin blocks Kras-dependent reprogramming of acini into pancreatic cancer precursor lesions in mice. J. Clin. Invest. 120 (2010), 508–520.
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 508-520
-
-
Morris, J.P.1
Cano, D.A.2
Sekine, S.3
Wang, S.C.4
Hebrok, M.5
-
87
-
-
74049139927
-
Preparing for the first breath: genetic and cellular mechanisms in the development of the vertebrate respiratory system
-
Morrisey, E.E., Hogan, B.L.M., Preparing for the first breath: genetic and cellular mechanisms in the development of the vertebrate respiratory system. Dev. Cell 18 (2010), 8–23.
-
(2010)
Dev. Cell
, vol.18
, pp. 8-23
-
-
Morrisey, E.E.1
Hogan, B.L.M.2
-
88
-
-
45849093670
-
The what, where, when and how of Wnt/beta-catenin signaling in pancreas development
-
Murtaugh, L.C., The what, where, when and how of Wnt/beta-catenin signaling in pancreas development. Organogenesis 4 (2008), 81–86.
-
(2008)
Organogenesis
, vol.4
, pp. 81-86
-
-
Murtaugh, L.C.1
-
89
-
-
0344736673
-
Notch signaling controls multiple steps of pancreatic differentiation
-
Murtaugh, L.C., Stanger, B.Z., Kwan, K.M., Melton, D.A., Notch signaling controls multiple steps of pancreatic differentiation. Proc. Natl. Acad. Sci. USA 100 (2003), 14920–14925.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 14920-14925
-
-
Murtaugh, L.C.1
Stanger, B.Z.2
Kwan, K.M.3
Melton, D.A.4
-
90
-
-
52449122255
-
Conditional ablation of Notch signaling in pancreatic development
-
Nakhai, H., Siveke, J.T., Klein, B., Mendoza-Torres, L., Mazur, P.K., Algül, H., Radtke, F., Strobl, L., Zimber-Strobl, U., Schmid, R.M., Conditional ablation of Notch signaling in pancreatic development. Development 135 (2008), 2757–2765.
-
(2008)
Development
, vol.135
, pp. 2757-2765
-
-
Nakhai, H.1
Siveke, J.T.2
Klein, B.3
Mendoza-Torres, L.4
Mazur, P.K.5
Algül, H.6
Radtke, F.7
Strobl, L.8
Zimber-Strobl, U.9
Schmid, R.M.10
-
91
-
-
33644537403
-
The vascular basement membrane: a niche for insulin gene expression and Beta cell proliferation
-
Nikolova, G., Jabs, N., Konstantinova, I., Domogatskaya, A., Tryggvason, K., Sorokin, L., Fässler, R., Gu, G., Gerber, H.P., Ferrara, N., et al. The vascular basement membrane: a niche for insulin gene expression and Beta cell proliferation. Dev. Cell 10 (2006), 397–405.
-
(2006)
Dev. Cell
, vol.10
, pp. 397-405
-
-
Nikolova, G.1
Jabs, N.2
Konstantinova, I.3
Domogatskaya, A.4
Tryggvason, K.5
Sorokin, L.6
Fässler, R.7
Gu, G.8
Gerber, H.P.9
Ferrara, N.10
-
92
-
-
34848887156
-
Recovery from diabetes in mice by beta cell regeneration
-
Nir, T., Melton, D.A., Dor, Y., Recovery from diabetes in mice by beta cell regeneration. J. Clin. Invest. 117 (2007), 2553–2561.
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 2553-2561
-
-
Nir, T.1
Melton, D.A.2
Dor, Y.3
-
93
-
-
33646194560
-
A switch from MafB to MafA expression accompanies differentiation to pancreatic beta-cells
-
Nishimura, W., Kondo, T., Salameh, T., El Khattabi, I., Dodge, R., Bonner-Weir, S., Sharma, A., A switch from MafB to MafA expression accompanies differentiation to pancreatic beta-cells. Dev. Biol. 293 (2006), 526–539.
-
(2006)
Dev. Biol.
, vol.293
, pp. 526-539
-
-
Nishimura, W.1
Kondo, T.2
Salameh, T.3
El Khattabi, I.4
Dodge, R.5
Bonner-Weir, S.6
Sharma, A.7
-
94
-
-
0344063697
-
FGF10 signaling maintains the pancreatic progenitor cell state revealing a novel role of Notch in organ development
-
Norgaard, G.A., Jensen, J.N., Jensen, J., FGF10 signaling maintains the pancreatic progenitor cell state revealing a novel role of Notch in organ development. Dev. Biol. 264 (2003), 323–338.
-
(2003)
Dev. Biol.
, vol.264
, pp. 323-338
-
-
Norgaard, G.A.1
Jensen, J.N.2
Jensen, J.3
-
95
-
-
70449625611
-
New strategies to generate induced pluripotent stem cells
-
O'Malley, J., Woltjen, K., Kaji, K., New strategies to generate induced pluripotent stem cells. Curr. Opin. Biotechnol. 20 (2009), 516–521.
-
(2009)
Curr. Opin. Biotechnol.
, vol.20
, pp. 516-521
-
-
O'Malley, J.1
Woltjen, K.2
Kaji, K.3
-
96
-
-
0029868156
-
PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum
-
Offield, M.F., Jetton, T.L., Labosky, P.A., Ray, M., Stein, R.W., Magnuson, M.A., Hogan, B.L., Wright, C.V., PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum. Development 122 (1996), 983–995.
-
(1996)
Development
, vol.122
, pp. 983-995
-
-
Offield, M.F.1
Jetton, T.L.2
Labosky, P.A.3
Ray, M.4
Stein, R.W.5
Magnuson, M.A.6
Hogan, B.L.7
Wright, C.V.8
-
97
-
-
0027384997
-
IPF1, a homeodomain-containing transactivator of the insulin gene
-
Ohlsson, H., Karlsson, K., Edlund, T., IPF1, a homeodomain-containing transactivator of the insulin gene. EMBO J. 12 (1993), 4251–4259.
-
(1993)
EMBO J.
, vol.12
, pp. 4251-4259
-
-
Ohlsson, H.1
Karlsson, K.2
Edlund, T.3
-
99
-
-
50549089957
-
Disease-specific induced pluripotent stem cells
-
Park, I.H., Arora, N., Huo, H., Maherali, N., Ahfeldt, T., Shimamura, A., Lensch, M.W., Cowan, C., Hochedlinger, K., Daley, G.Q., Disease-specific induced pluripotent stem cells. Cell 134 (2008), 877–886.
-
(2008)
Cell
, vol.134
, pp. 877-886
-
-
Park, I.H.1
Arora, N.2
Huo, H.3
Maherali, N.4
Ahfeldt, T.5
Shimamura, A.6
Lensch, M.W.7
Cowan, C.8
Hochedlinger, K.9
Daley, G.Q.10
-
100
-
-
0026573783
-
Adaptation of islets of Langerhans to pregnancy: increased islet cell proliferation and insulin secretion correlates with the onset of placental lactogen secretion
-
Parsons, J.A., Brelje, T.C., Sorenson, R.L., Adaptation of islets of Langerhans to pregnancy: increased islet cell proliferation and insulin secretion correlates with the onset of placental lactogen secretion. Endocrinology 130 (1992), 1459–1466.
-
(1992)
Endocrinology
, vol.130
, pp. 1459-1466
-
-
Parsons, J.A.1
Brelje, T.C.2
Sorenson, R.L.3
-
101
-
-
33751209187
-
Hedgehog/Ras interactions regulate early stages of pancreatic cancer
-
Pasca di Magliano, M., Sekine, S., Ermilov, A., Ferris, J., Dlugosz, A.A., Hebrok, M., Hedgehog/Ras interactions regulate early stages of pancreatic cancer. Genes Dev. 20 (2006), 3161–3173.
-
(2006)
Genes Dev.
, vol.20
, pp. 3161-3173
-
-
Pasca di Magliano, M.1
Sekine, S.2
Ermilov, A.3
Ferris, J.4
Dlugosz, A.A.5
Hebrok, M.6
-
102
-
-
0033602021
-
Analysis of pancreatic development using a cell lineage label
-
Percival, A.C., Slack, J.M., Analysis of pancreatic development using a cell lineage label. Exp. Cell Res. 247 (1999), 123–132.
-
(1999)
Exp. Cell Res.
, vol.247
, pp. 123-132
-
-
Percival, A.C.1
Slack, J.M.2
-
103
-
-
34249322654
-
Dynamics of embryonic pancreas development using real-time imaging
-
Puri, S., Hebrok, M., Dynamics of embryonic pancreas development using real-time imaging. Dev. Biol. 306 (2007), 82–93.
-
(2007)
Dev. Biol.
, vol.306
, pp. 82-93
-
-
Puri, S.1
Hebrok, M.2
-
104
-
-
0034100823
-
Reversal of insulin-dependent diabetes using islets generated in vitro from pancreatic stem cells
-
Ramiya, V.K., Maraist, M., Arfors, K.E., Schatz, D.A., Peck, A.B., Cornelius, J.G., Reversal of insulin-dependent diabetes using islets generated in vitro from pancreatic stem cells. Nat. Med. 6 (2000), 278–282.
-
(2000)
Nat. Med.
, vol.6
, pp. 278-282
-
-
Ramiya, V.K.1
Maraist, M.2
Arfors, K.E.3
Schatz, D.A.4
Peck, A.B.5
Cornelius, J.G.6
-
105
-
-
0032937751
-
Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in beta-islet cell hyperplasia
-
Rane, S.G., Dubus, P., Mettus, R.V., Galbreath, E.J., Boden, G., Reddy, E.P., Barbacid, M., Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in beta-islet cell hyperplasia. Nat. Genet. 22 (1999), 44–52.
-
(1999)
Nat. Genet.
, vol.22
, pp. 44-52
-
-
Rane, S.G.1
Dubus, P.2
Mettus, R.V.3
Galbreath, E.J.4
Boden, G.5
Reddy, E.P.6
Barbacid, M.7
-
106
-
-
66649128739
-
Adaptive beta-cell proliferation is severely restricted with advanced age
-
Rankin, M.M., Kushner, J.A., Adaptive beta-cell proliferation is severely restricted with advanced age. Diabetes 58 (2009), 1365–1372.
-
(2009)
Diabetes
, vol.58
, pp. 1365-1372
-
-
Rankin, M.M.1
Kushner, J.A.2
-
107
-
-
0024354234
-
Role of periductal and ductular epithelial cells of the adult rat pancreas in pancreatic hepatocyte lineage. A change in the differentiation commitment
-
Rao, M.S., Dwivedi, R.S., Yeldandi, A.V., Subbarao, V., Tan, X.D., Usman, M.I., Thangada, S., Nemali, M.R., Kumar, S., Scarpelli, D.G., et al. Role of periductal and ductular epithelial cells of the adult rat pancreas in pancreatic hepatocyte lineage. A change in the differentiation commitment. Am. J. Pathol. 134 (1989), 1069–1086.
-
(1989)
Am. J. Pathol.
, vol.134
, pp. 1069-1086
-
-
Rao, M.S.1
Dwivedi, R.S.2
Yeldandi, A.V.3
Subbarao, V.4
Tan, X.D.5
Usman, M.I.6
Thangada, S.7
Nemali, M.R.8
Kumar, S.9
Scarpelli, D.G.10
-
108
-
-
0035423751
-
Distinct mesodermal signals, including BMPs from the septum transversum mesenchyme, are required in combination for hepatogenesis from the endoderm
-
Rossi, J.M., Dunn, N.R., Hogan, B.L., Zaret, K.S., Distinct mesodermal signals, including BMPs from the septum transversum mesenchyme, are required in combination for hepatogenesis from the endoderm. Genes Dev. 15 (2001), 1998–2009.
-
(2001)
Genes Dev.
, vol.15
, pp. 1998-2009
-
-
Rossi, J.M.1
Dunn, N.R.2
Hogan, B.L.3
Zaret, K.S.4
-
109
-
-
34547516561
-
Wnt signaling regulates pancreatic beta cell proliferation
-
Rulifson, I.C., Karnik, S.K., Heiser, P.W., ten Berge, D., Chen, H., Gu, X., Taketo, M.M., Nusse, R., Hebrok, M., Kim, S.K., Wnt signaling regulates pancreatic beta cell proliferation. Proc. Natl. Acad. Sci. USA 104 (2007), 6247–6252.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 6247-6252
-
-
Rulifson, I.C.1
Karnik, S.K.2
Heiser, P.W.3
ten Berge, D.4
Chen, H.5
Gu, X.6
Taketo, M.M.7
Nusse, R.8
Hebrok, M.9
Kim, S.K.10
-
110
-
-
0034524101
-
Homeobox gene Nkx6.1 lies downstream of Nkx2.2 in the major pathway of beta-cell formation in the pancreas
-
Sander, M., Sussel, L., Conners, J., Scheel, D., Kalamaras, J., Dela Cruz, F., Schwitzgebel, V., Hayes-Jordan, A., German, M., Homeobox gene Nkx6.1 lies downstream of Nkx2.2 in the major pathway of beta-cell formation in the pancreas. Development 127 (2000), 5533–5540.
-
(2000)
Development
, vol.127
, pp. 5533-5540
-
-
Sander, M.1
Sussel, L.2
Conners, J.3
Scheel, D.4
Kalamaras, J.5
Dela Cruz, F.6
Schwitzgebel, V.7
Hayes-Jordan, A.8
German, M.9
-
111
-
-
20344394437
-
Cell-replacement therapy for diabetes: Generating functional insulin-producing tissue from adult human liver cells
-
Sapir, T., Shternhall, K., Meivar-Levy, I., Blumenfeld, T., Cohen, H., Skutelsky, E., Eventov-Friedman, S., Barshack, I., Goldberg, I., Pri-Chen, S., et al. Cell-replacement therapy for diabetes: Generating functional insulin-producing tissue from adult human liver cells. Proc. Natl. Acad. Sci. USA 102 (2005), 7964–7969.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 7964-7969
-
-
Sapir, T.1
Shternhall, K.2
Meivar-Levy, I.3
Blumenfeld, T.4
Cohen, H.5
Skutelsky, E.6
Eventov-Friedman, S.7
Barshack, I.8
Goldberg, I.9
Pri-Chen, S.10
-
112
-
-
0033825383
-
Expression of neurogenin3 reveals an islet cell precursor population in the pancreas
-
Schwitzgebel, V.M., Scheel, D.W., Conners, J.R., Kalamaras, J., Lee, J.E., Anderson, D.J., Sussel, L., Johnson, J.D., German, M.S., Expression of neurogenin3 reveals an islet cell precursor population in the pancreas. Development 127 (2000), 3533–3542.
-
(2000)
Development
, vol.127
, pp. 3533-3542
-
-
Schwitzgebel, V.M.1
Scheel, D.W.2
Conners, J.R.3
Kalamaras, J.4
Lee, J.E.5
Anderson, D.J.6
Sussel, L.7
Johnson, J.D.8
German, M.S.9
-
113
-
-
58149511982
-
Four-dimensional realistic modeling of pancreatic organogenesis
-
Setty, Y., Cohen, I.R., Dor, Y., Harel, D., Four-dimensional realistic modeling of pancreatic organogenesis. Proc. Natl. Acad. Sci. USA 105 (2008), 20374–20379.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 20374-20379
-
-
Setty, Y.1
Cohen, I.R.2
Dor, Y.3
Harel, D.4
-
114
-
-
33846910410
-
SOX9 is required for maintenance of the pancreatic progenitor cell pool
-
Seymour, P.A., Freude, K.K., Tran, M.N., Mayes, E.E., Jensen, J., Kist, R., Scherer, G., Sander, M., SOX9 is required for maintenance of the pancreatic progenitor cell pool. Proc. Natl. Acad. Sci. USA 104 (2007), 1865–1870.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 1865-1870
-
-
Seymour, P.A.1
Freude, K.K.2
Tran, M.N.3
Mayes, E.E.4
Jensen, J.5
Kist, R.6
Scherer, G.7
Sander, M.8
-
115
-
-
53649102798
-
A dosage-dependent requirement for Sox9 in pancreatic endocrine cell formation
-
Seymour, P.A., Freude, K.K., Dubois, C.L., Shih, H.P., Patel, N.A., Sander, M., A dosage-dependent requirement for Sox9 in pancreatic endocrine cell formation. Dev. Biol. 323 (2008), 19–30.
-
(2008)
Dev. Biol.
, vol.323
, pp. 19-30
-
-
Seymour, P.A.1
Freude, K.K.2
Dubois, C.L.3
Shih, H.P.4
Patel, N.A.5
Sander, M.6
-
116
-
-
33749070784
-
International trial of the Edmonton protocol for islet transplantation
-
Shapiro, A.M., Ricordi, C., Hering, B.J., Auchincloss, H., Lindblad, R., Robertson, R.P., Secchi, A., Brendel, M.D., Berney, T., Brennan, D.C., et al. International trial of the Edmonton protocol for islet transplantation. N. Engl. J. Med. 355 (2006), 1318–1330.
-
(2006)
N. Engl. J. Med.
, vol.355
, pp. 1318-1330
-
-
Shapiro, A.M.1
Ricordi, C.2
Hering, B.J.3
Auchincloss, H.4
Lindblad, R.5
Robertson, R.P.6
Secchi, A.7
Brendel, M.D.8
Berney, T.9
Brennan, D.C.10
-
117
-
-
0033009460
-
The homeodomain protein IDX-1 increases after an early burst of proliferation during pancreatic regeneration
-
Sharma, A., Zangen, D.H., Reitz, P., Taneja, M., Lissauer, M.E., Miller, C.P., Weir, G.C., Habener, J.F., Bonner-Weir, S., The homeodomain protein IDX-1 increases after an early burst of proliferation during pancreatic regeneration. Diabetes 48 (1999), 507–513.
-
(1999)
Diabetes
, vol.48
, pp. 507-513
-
-
Sharma, A.1
Zangen, D.H.2
Reitz, P.3
Taneja, M.4
Lissauer, M.E.5
Miller, C.P.6
Weir, G.C.7
Habener, J.F.8
Bonner-Weir, S.9
-
118
-
-
71649092364
-
Pancreatic exocrine duct cells give rise to insulin-producing beta cells during embryogenesis but not after birth
-
Solar, M., Cardalda, C., Houbracken, I., Martín, M., Maestro, M.A., De Medts, N., Xu, X., Grau, V., Heimberg, H., Bouwens, L., Ferrer, J., Pancreatic exocrine duct cells give rise to insulin-producing beta cells during embryogenesis but not after birth. Dev. Cell 17 (2009), 849–860.
-
(2009)
Dev. Cell
, vol.17
, pp. 849-860
-
-
Solar, M.1
Cardalda, C.2
Houbracken, I.3
Martín, M.4
Maestro, M.A.5
De Medts, N.6
Xu, X.7
Grau, V.8
Heimberg, H.9
Bouwens, L.10
Ferrer, J.11
-
119
-
-
67650246360
-
Sox17 regulates organ lineage segregation of ventral foregut progenitor cells
-
Spence, J.R., Lange, A.W., Lin, S.C., Kaestner, K.H., Lowy, A.M., Kim, I., Whitsett, J.A., Wells, J.M., Sox17 regulates organ lineage segregation of ventral foregut progenitor cells. Dev. Cell 17 (2009), 62–74.
-
(2009)
Dev. Cell
, vol.17
, pp. 62-74
-
-
Spence, J.R.1
Lange, A.W.2
Lin, S.C.3
Kaestner, K.H.4
Lowy, A.M.5
Kim, I.6
Whitsett, J.A.7
Wells, J.M.8
-
120
-
-
0031253820
-
Early-onset type-II diabetes mellitus (MODY4) linked to IPF1
-
Stoffers, D.A., Ferrer, J., Clarke, W.L., Habener, J.F., Early-onset type-II diabetes mellitus (MODY4) linked to IPF1. Nat. Genet. 17 (1997), 138–139.
-
(1997)
Nat. Genet.
, vol.17
, pp. 138-139
-
-
Stoffers, D.A.1
Ferrer, J.2
Clarke, W.L.3
Habener, J.F.4
-
121
-
-
0346727348
-
Conversion of biliary system to pancreatic tissue in Hes1-deficient mice
-
Sumazaki, R., Shiojiri, N., Isoyama, S., Masu, M., Keino-Masu, K., Osawa, M., Nakauchi, H., Kageyama, R., Matsui, A., Conversion of biliary system to pancreatic tissue in Hes1-deficient mice. Nat. Genet. 36 (2004), 83–87.
-
(2004)
Nat. Genet.
, vol.36
, pp. 83-87
-
-
Sumazaki, R.1
Shiojiri, N.2
Isoyama, S.3
Masu, M.4
Keino-Masu, K.5
Osawa, M.6
Nakauchi, H.7
Kageyama, R.8
Matsui, A.9
-
122
-
-
0031843386
-
Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic beta cells
-
Sussel, L., Kalamaras, J., Hartigan-O'Connor, D.J., Meneses, J.J., Pedersen, R.A., Rubenstein, J.L., German, M.S., Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic beta cells. Development 125 (1998), 2213–2221.
-
(1998)
Development
, vol.125
, pp. 2213-2221
-
-
Sussel, L.1
Kalamaras, J.2
Hartigan-O'Connor, D.J.3
Meneses, J.J.4
Pedersen, R.A.5
Rubenstein, J.L.6
German, M.S.7
-
123
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
Takahashi, K., Yamanaka, S., Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126 (2006), 663–676.
-
(2006)
Cell
, vol.126
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
124
-
-
36248966518
-
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
-
Takahashi, K., Tanabe, K., Ohnuki, M., Narita, M., Ichisaka, T., Tomoda, K., Yamanaka, S., Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131 (2007), 861–872.
-
(2007)
Cell
, vol.131
, pp. 861-872
-
-
Takahashi, K.1
Tanabe, K.2
Ohnuki, M.3
Narita, M.4
Ichisaka, T.5
Tomoda, K.6
Yamanaka, S.7
-
125
-
-
24144473869
-
Very slow turnover of beta-cells in aged adult mice
-
Teta, M., Long, S.Y., Wartschow, L.M., Rankin, M.M., Kushner, J.A., Very slow turnover of beta-cells in aged adult mice. Diabetes 54 (2005), 2557–2567.
-
(2005)
Diabetes
, vol.54
, pp. 2557-2567
-
-
Teta, M.1
Long, S.Y.2
Wartschow, L.M.3
Rankin, M.M.4
Kushner, J.A.5
-
126
-
-
34247644369
-
Growth and regeneration of adult beta cells does not involve specialized progenitors
-
Teta, M., Rankin, M.M., Long, S.Y., Stein, G.M., Kushner, J.A., Growth and regeneration of adult beta cells does not involve specialized progenitors. Dev. Cell 12 (2007), 817–826.
-
(2007)
Dev. Cell
, vol.12
, pp. 817-826
-
-
Teta, M.1
Rankin, M.M.2
Long, S.Y.3
Stein, G.M.4
Kushner, J.A.5
-
127
-
-
14844333138
-
Distinct populations of endoderm cells converge to generate the embryonic liver bud and ventral foregut tissues
-
Tremblay, K.D., Zaret, K.S., Distinct populations of endoderm cells converge to generate the embryonic liver bud and ventral foregut tissues. Dev. Biol. 280 (2005), 87–99.
-
(2005)
Dev. Biol.
, vol.280
, pp. 87-99
-
-
Tremblay, K.D.1
Zaret, K.S.2
-
128
-
-
66649084335
-
Age-dependent decline in beta-cell proliferation restricts the capacity of beta-cell regeneration in mice
-
Tschen, S.I., Dhawan, S., Gurlo, T., Bhushan, A., Age-dependent decline in beta-cell proliferation restricts the capacity of beta-cell regeneration in mice. Diabetes 58 (2009), 1312–1320.
-
(2009)
Diabetes
, vol.58
, pp. 1312-1320
-
-
Tschen, S.I.1
Dhawan, S.2
Gurlo, T.3
Bhushan, A.4
-
129
-
-
0034686028
-
Targeted expression of placental lactogen in the beta cells of transgenic mice results in beta cell proliferation, islet mass augmentation, and hypoglycemia
-
Vasavada, R.C., Garcia-Ocaña, A., Zawalich, W.S., Sorenson, R.L., Dann, P., Syed, M., Ogren, L., Talamantes, F., Stewart, A.F., Targeted expression of placental lactogen in the beta cells of transgenic mice results in beta cell proliferation, islet mass augmentation, and hypoglycemia. J. Biol. Chem. 275 (2000), 15399–15406.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 15399-15406
-
-
Vasavada, R.C.1
Garcia-Ocaña, A.2
Zawalich, W.S.3
Sorenson, R.L.4
Dann, P.5
Syed, M.6
Ogren, L.7
Talamantes, F.8
Stewart, A.F.9
-
130
-
-
67649995217
-
Dynamic signaling network for the specification of embryonic pancreas and liver progenitors
-
Wandzioch, E., Zaret, K.S., Dynamic signaling network for the specification of embryonic pancreas and liver progenitors. Science 324 (2009), 1707–1710.
-
(2009)
Science
, vol.324
, pp. 1707-1710
-
-
Wandzioch, E.1
Zaret, K.S.2
-
131
-
-
33846316025
-
Adenovirus transduction is required for the correction of diabetes using Pdx-1 or Neurogenin-3 in the liver
-
Wang, A.Y., Ehrhardt, A., Xu, H., Kay, M.A., Adenovirus transduction is required for the correction of diabetes using Pdx-1 or Neurogenin-3 in the liver. Mol. Ther. 15 (2007), 255–263.
-
(2007)
Mol. Ther.
, vol.15
, pp. 255-263
-
-
Wang, A.Y.1
Ehrhardt, A.2
Xu, H.3
Kay, M.A.4
-
132
-
-
50949114536
-
PANIC-ATTAC: a mouse model for inducible and reversible beta-cell ablation
-
Wang, Z.V., Mu, J., Schraw, T.D., Gautron, L., Elmquist, J.K., Zhang, B.B., Brownlee, M., Scherer, P.E., PANIC-ATTAC: a mouse model for inducible and reversible beta-cell ablation. Diabetes 57 (2008), 2137–2148.
-
(2008)
Diabetes
, vol.57
, pp. 2137-2148
-
-
Wang, Z.V.1
Mu, J.2
Schraw, T.D.3
Gautron, L.4
Elmquist, J.K.5
Zhang, B.B.6
Brownlee, M.7
Scherer, P.E.8
-
133
-
-
67649865643
-
Sustained Neurog3 expression in hormone-expressing islet cells is required for endocrine maturation and function
-
Wang, S., Jensen, J.N., Seymour, P.A., Hsu, W., Dor, Y., Sander, M., Magnuson, M.A., Serup, P., Gu, G., Sustained Neurog3 expression in hormone-expressing islet cells is required for endocrine maturation and function. Proc. Natl. Acad. Sci. USA 106 (2009), 9715–9720.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 9715-9720
-
-
Wang, S.1
Jensen, J.N.2
Seymour, P.A.3
Hsu, W.4
Dor, Y.5
Sander, M.6
Magnuson, M.A.7
Serup, P.8
Gu, G.9
-
134
-
-
70350330155
-
Towards better understanding of the contributions of overwork and glucotoxicity to the beta-cell inadequacy of type 2 diabetes
-
Weir, G.C., Marselli, L., Marchetti, P., Katsuta, H., Jung, M.H., Bonner-Weir, S., Towards better understanding of the contributions of overwork and glucotoxicity to the beta-cell inadequacy of type 2 diabetes. Diabetes Obes. Metab. 11:Suppl 4 (2009), 82–90.
-
(2009)
Diabetes Obes. Metab.
, vol.11
, pp. 82-90
-
-
Weir, G.C.1
Marselli, L.2
Marchetti, P.3
Katsuta, H.4
Jung, M.H.5
Bonner-Weir, S.6
-
135
-
-
0034093614
-
Early mouse endoderm is patterned by soluble factors from adjacent germ layers
-
Wells, J.M., Melton, D.A., Early mouse endoderm is patterned by soluble factors from adjacent germ layers. Development 127 (2000), 1563–1572.
-
(2000)
Development
, vol.127
, pp. 1563-1572
-
-
Wells, J.M.1
Melton, D.A.2
-
136
-
-
62349089109
-
Pancreatic cancer: translating lessons from mouse models and hereditary syndromes
-
Wescott, M.P., Rustgi, A.K., Pancreatic cancer: translating lessons from mouse models and hereditary syndromes. Cancer Prev. Res. 1 (2008), 503–506.
-
(2008)
Cancer Prev. Res.
, vol.1
, pp. 503-506
-
-
Wescott, M.P.1
Rustgi, A.K.2
-
137
-
-
0037213587
-
Gene expression cascades in pancreatic development
-
Wilson, M.E., Scheel, D., German, M.S., Gene expression cascades in pancreatic development. Mech. Dev. 120 (2003), 65–80.
-
(2003)
Mech. Dev.
, vol.120
, pp. 65-80
-
-
Wilson, M.E.1
Scheel, D.2
German, M.S.3
-
138
-
-
38749108893
-
Beta cells can be generated from endogenous progenitors in injured adult mouse pancreas
-
Xu, X., D'Hoker, J., Stangé, G., Bonné, S., De Leu, N., Xiao, X., Van de Casteele, M., Mellitzer, G., Ling, Z., Pipeleers, D., et al. Beta cells can be generated from endogenous progenitors in injured adult mouse pancreas. Cell 132 (2008), 197–207.
-
(2008)
Cell
, vol.132
, pp. 197-207
-
-
Xu, X.1
D'Hoker, J.2
Stangé, G.3
Bonné, S.4
De Leu, N.5
Xiao, X.6
Van de Casteele, M.7
Mellitzer, G.8
Ling, Z.9
Pipeleers, D.10
-
139
-
-
61749094740
-
Neurogenin3 is sufficient for transdetermination of hepatic progenitor cells into neo-islets in vivo but not transdifferentiation of hepatocytes
-
Yechoor, V., Liu, V., Espiritu, C., Paul, A., Oka, K., Kojima, H., Chan, L., Neurogenin3 is sufficient for transdetermination of hepatic progenitor cells into neo-islets in vivo but not transdifferentiation of hepatocytes. Dev. Cell 16 (2009), 358–373.
-
(2009)
Dev. Cell
, vol.16
, pp. 358-373
-
-
Yechoor, V.1
Liu, V.2
Espiritu, C.3
Paul, A.4
Oka, K.5
Kojima, H.6
Chan, L.7
-
140
-
-
1342263524
-
Endothelial cell interactions initiate dorsal pancreas development by selectively inducing the transcription factor Ptf1a
-
Yoshitomi, H., Zaret, K.S., Endothelial cell interactions initiate dorsal pancreas development by selectively inducing the transcription factor Ptf1a. Development 131 (2004), 807–817.
-
(2004)
Development
, vol.131
, pp. 807-817
-
-
Yoshitomi, H.1
Zaret, K.S.2
-
141
-
-
34250893048
-
A multipotent progenitor domain guides pancreatic organogenesis
-
Zhou, Q., Law, A.C., Rajagopal, J., Anderson, W.J., Gray, P.A., Melton, D.A., A multipotent progenitor domain guides pancreatic organogenesis. Dev. Cell 13 (2007), 103–114.
-
(2007)
Dev. Cell
, vol.13
, pp. 103-114
-
-
Zhou, Q.1
Law, A.C.2
Rajagopal, J.3
Anderson, W.J.4
Gray, P.A.5
Melton, D.A.6
-
142
-
-
53349178722
-
In vivo reprogramming of adult pancreatic exocrine cells to beta-cells
-
Zhou, Q., Brown, J., Kanarek, A., Rajagopal, J., Melton, D.A., In vivo reprogramming of adult pancreatic exocrine cells to beta-cells. Nature 455 (2008), 627–632.
-
(2008)
Nature
, vol.455
, pp. 627-632
-
-
Zhou, Q.1
Brown, J.2
Kanarek, A.3
Rajagopal, J.4
Melton, D.A.5
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