The CASTOR Proteins Are Arginine Sensors for the mTORC1 Pathway

Cell

Volumn 165, Issue 1, 2016, Pages 153-164

  Chantranupong, Lynne ^a,b,c   Scaria, Sonia M ^a,b,c   Saxton, Robert A ^a,b,c   Gygi, Melanie P ^d   Shen, Kuang ^a,b,c   Wyant, Gregory A ^a,b,c   Wang, Tim ^a,b,c   Harper, J Wade ^d   Gygi, Steven P ^d   Sabatini, David M ^a,b,c  

^a WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c KOCH INSTITUTE FOR INTEGRATIVE CANCER RESEARCH   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; CASTOR1 PROTEIN; CASTOR2 PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; PROTEIN; UNCLASSIFIED DRUG; CARRIER PROTEIN; CASTOR1 PROTEIN, HUMAN; CASTOR2 PROTEIN, HUMAN; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MULTIPROTEIN COMPLEX; TARGET OF RAPAMYCIN KINASE;

ARGININE SENSOR; ARTICLE; CELL LYSATE; CONTROLLED STUDY; CYTOLYSIS; DISSOCIATION CONSTANT; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; IN VITRO STUDY; MOLECULAR SENSOR; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; HEK293 CELL LINE; METABOLISM; PROTEIN MULTIMERIZATION;

ARGININE; CARRIER PROTEINS; HEK293 CELLS; HUMANS; MULTIPROTEIN COMPLEXES; PROTEIN MULTIMERIZATION; TOR SERINE-THREONINE KINASES;

EID: 84959880781     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2016.02.035     Document Type: Article

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