Probing Biased Signaling in Chemokine Receptors

Methods in Enzymology

Volumn 570, Issue , 2016, Pages 155-186

  Amarandi, Roxana Maria ^a,b   Hjortø, Gertrud Malene ^a   Rosenkilde, Mette Marie ^a   Karlshøj, Stefanie ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b ALEXANDRU IOAN CUZA UNIVERSITY OF IASI   (Romania)

Author keywords

7TMR; Bias; cAMP; Chemokine system; Chemotaxis; ERK; GPCR; GTP S; Internalization; IP3; Arrestin

Indexed keywords

BETA ARRESTIN; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CXCR3; CHEMOKINE RECEPTOR CXCR4; CHEMOKINE RECEPTOR CXCR7; CXCL9 CHEMOKINE; GUANINE NUCLEOTIDE BINDING PROTEIN; CHEMOKINE; CYCLIC AMP; G PROTEIN COUPLED RECEPTOR; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); LIGAND;

ACTIN POLYMERIZATION; ALLOSTERISM; ANTIGEN BINDING; APOPTOSIS; CELL MIGRATION; CELL SURFACE; CELL VIABILITY; DRUG DEVELOPMENT; ENDOPLASMIC RETICULUM; GENETIC TRANSCRIPTION; INTRACELLULAR SIGNALING; LEUKOCYTE MIGRATION; LIGAND BINDING; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; RECEPTOR DOWN REGULATION; T LYMPHOCYTE; ANIMAL; CHEMOTAXIS; DRUG EFFECTS; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; METABOLISM; MOLECULAR BIOLOGY; MOLECULARLY TARGETED THERAPY; PROCEDURES; SIGNAL TRANSDUCTION;

ANIMALS; BETA-ARRESTINS; CHEMOKINES; CHEMOTAXIS; CYCLIC AMP; ENZYME-LINKED IMMUNOSORBENT ASSAY; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); HUMANS; LIGANDS; MOLECULAR BIOLOGY; MOLECULAR TARGETED THERAPY; RECEPTORS, CHEMOKINE; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION;

EID: 84959084638     PISSN: 00766879     EISSN: 15577988     Source Type: Book Series    
DOI: 10.1016/bs.mie.2015.09.001     Document Type: Chapter

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