Kaposi's sarcoma-associated herpesvirus-encoded G protein-coupled receptor ORF74 constitutively activates p44/p42 MAPK and Akt via Gi and phospholipase C-dependent signaling pathways

Journal of Virology

Volumn 76, Issue 4, 2002, Pages 1744-1752

  Smit, Martine J ^a   Verzijl, Dennis ^a   Casarosa, Paola ^a   Navis, Marjon ^a   Timmerman, Henk ^a   Leurs, Rob ^a  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR; G PROTEIN COUPLED RECEPTOR; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOLIPASE C; PROTEIN KINASE B; PROTEIN KINASE C; PROTEIN ORF74; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANIMAL CELL; APOPTOSIS; ARTICLE; CARCINOGENESIS; CELL PROLIFERATION; CELL STRAIN COS7; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN HERPESVIRUS 8; KAPOSI SARCOMA; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALS; CERCOPITHECUS AETHIOPS; COS CELLS; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, NEOPLASTIC; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; HERPESVIRUS 8, HUMAN; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHOLIPASE C; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, CELL SURFACE; RECEPTORS, CHEMOKINE; SIGNAL TRANSDUCTION; TRANSFECTION; VIRAL PROTEINS;

EID: 0036146194     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.76.4.1744-1752.2002     Document Type: Article

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