-
1
-
-
84891163628
-
Role of cytokines in intervertebral disc degeneration: pain and disc content
-
Risbud M.V., Shapiro I.M. Role of cytokines in intervertebral disc degeneration: pain and disc content. Nat Rev Rheumatol 2014, 10(1):44-56.
-
(2014)
Nat Rev Rheumatol
, vol.10
, Issue.1
, pp. 44-56
-
-
Risbud, M.V.1
Shapiro, I.M.2
-
2
-
-
84926420130
-
Stem cell therapy for intervertebral disc regeneration: obstacles and solutions
-
Sakai D., Andersson G.B. Stem cell therapy for intervertebral disc regeneration: obstacles and solutions. Nat Rev Rheumatol 2015, 11(4):243-256.
-
(2015)
Nat Rev Rheumatol
, vol.11
, Issue.4
, pp. 243-256
-
-
Sakai, D.1
Andersson, G.B.2
-
3
-
-
33750537050
-
Microendoscopic discectomy for lumbar disc herniation: surgical technique and outcome in 873 consecutive cases
-
Wu X., Zhuang S., Mao Z., Chen H. Microendoscopic discectomy for lumbar disc herniation: surgical technique and outcome in 873 consecutive cases. Spine (Phila Pa 1976) 2006, 31(23):2689-2694.
-
(2006)
Spine (Phila Pa 1976)
, vol.31
, Issue.23
, pp. 2689-2694
-
-
Wu, X.1
Zhuang, S.2
Mao, Z.3
Chen, H.4
-
4
-
-
38649132004
-
Surgical results of anterior corpectomy in the aged patients with cervical myelopathy
-
Lu J., Wu X., Li Y., Kong X. Surgical results of anterior corpectomy in the aged patients with cervical myelopathy. Eur Spine J 2008, 17(1):129-135.
-
(2008)
Eur Spine J
, vol.17
, Issue.1
, pp. 129-135
-
-
Lu, J.1
Wu, X.2
Li, Y.3
Kong, X.4
-
5
-
-
84871051576
-
Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010
-
Vos T., Flaxman A.D., Naghavi M., Lozano R., Michaud C., Ezzati M., et al. Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 2012, 380(9859):2163-2196.
-
(2012)
Lancet
, vol.380
, Issue.9859
, pp. 2163-2196
-
-
Vos, T.1
Flaxman, A.D.2
Naghavi, M.3
Lozano, R.4
Michaud, C.5
Ezzati, M.6
-
6
-
-
84908087752
-
Intervertebral disc regeneration: do nutrients lead the way
-
Huang Y.C., Urban J.P., Luk K.D. Intervertebral disc regeneration: do nutrients lead the way. Nat Rev Rheumatol 2014, 10(9):561-566.
-
(2014)
Nat Rev Rheumatol
, vol.10
, Issue.9
, pp. 561-566
-
-
Huang, Y.C.1
Urban, J.P.2
Luk, K.D.3
-
7
-
-
84926415990
-
Gene therapy approaches to regenerating the musculoskeletal system
-
Evans C.H., Huard J. Gene therapy approaches to regenerating the musculoskeletal system. Nat Rev Rheumatol 2015, 11(4):234-242.
-
(2015)
Nat Rev Rheumatol
, vol.11
, Issue.4
, pp. 234-242
-
-
Evans, C.H.1
Huard, J.2
-
8
-
-
78650866043
-
Degeneration and regeneration of the intervertebral disc: lessons from development
-
Smith L.J., Nerurkar N.L., Choi K.S., Harfe B.D., Elliott D.M. Degeneration and regeneration of the intervertebral disc: lessons from development. Dis Model Mech 2011, 4(1):31-41.
-
(2011)
Dis Model Mech
, vol.4
, Issue.1
, pp. 31-41
-
-
Smith, L.J.1
Nerurkar, N.L.2
Choi, K.S.3
Harfe, B.D.4
Elliott, D.M.5
-
9
-
-
84862855802
-
Ex vivo observation of human intervertebral disc tissue and cells isolated from degenerated intervertebral discs
-
Ciapetti G., Granchi D., Devescovi V., Leonardi E., Greggi T., Di S.M., et al. Ex vivo observation of human intervertebral disc tissue and cells isolated from degenerated intervertebral discs. Eur Spine J 2012, 21(Suppl 1):S10-S19.
-
(2012)
Eur Spine J
, vol.21
, pp. S10-S19
-
-
Ciapetti, G.1
Granchi, D.2
Devescovi, V.3
Leonardi, E.4
Greggi, T.5
Di, S.M.6
-
10
-
-
0036216444
-
Expression of chondrocyte markers by cells of normal and degenerate intervertebral discs
-
Sive J.I., Baird P., Jeziorsk M., Watkins A., Hoyland J.A., Freemont A.J. Expression of chondrocyte markers by cells of normal and degenerate intervertebral discs. Mol Pathol 2002, 55(2):91-97.
-
(2002)
Mol Pathol
, vol.55
, Issue.2
, pp. 91-97
-
-
Sive, J.I.1
Baird, P.2
Jeziorsk, M.3
Watkins, A.4
Hoyland, J.A.5
Freemont, A.J.6
-
11
-
-
33845360165
-
Programmed cell death in intervertebral disc degeneration
-
Zhao C.Q., Jiang L.S., Dai L.Y. Programmed cell death in intervertebral disc degeneration. Apoptosis 2006, 11(12):2079-2088.
-
(2006)
Apoptosis
, vol.11
, Issue.12
, pp. 2079-2088
-
-
Zhao, C.Q.1
Jiang, L.S.2
Dai, L.Y.3
-
12
-
-
0035890099
-
Mechanisms of age-related decline in insulin-like growth factor-I dependent proteoglycan synthesis in rat intervertebral disc cells
-
Okuda S., Myoui A., Ariga K., Nakase T., Yonenobu K., Yoshikawa H. Mechanisms of age-related decline in insulin-like growth factor-I dependent proteoglycan synthesis in rat intervertebral disc cells. Spine (Phila Pa 1976) 2001, 26(22):2421-2426.
-
(2001)
Spine (Phila Pa 1976)
, vol.26
, Issue.22
, pp. 2421-2426
-
-
Okuda, S.1
Myoui, A.2
Ariga, K.3
Nakase, T.4
Yonenobu, K.5
Yoshikawa, H.6
-
13
-
-
0037218780
-
Age-related changes in expression of transforming growth factor-beta and receptors in cells of intervertebral discs
-
Matsunaga S., Nagano S., Onishi T., Morimoto N., Suzuki S., Komiya S. Age-related changes in expression of transforming growth factor-beta and receptors in cells of intervertebral discs. J Neurosurg 2003, 98(1 Suppl):63-67.
-
(2003)
J Neurosurg
, vol.98
, Issue.1
, pp. 63-67
-
-
Matsunaga, S.1
Nagano, S.2
Onishi, T.3
Morimoto, N.4
Suzuki, S.5
Komiya, S.6
-
14
-
-
84904702784
-
Cellular senescence: from physiology to pathology
-
Munoz-Espin D., Serrano M. Cellular senescence: from physiology to pathology. Nat Rev Mol Cell Biol 2014, 15(7):482-496.
-
(2014)
Nat Rev Mol Cell Biol
, vol.15
, Issue.7
, pp. 482-496
-
-
Munoz-Espin, D.1
Serrano, M.2
-
15
-
-
84901288438
-
The role of senescent cells in ageing
-
van Deursen J.M. The role of senescent cells in ageing. Nature 2014, 509(7501):439-446.
-
(2014)
Nature
, vol.509
, Issue.7501
, pp. 439-446
-
-
van Deursen, J.M.1
-
16
-
-
84933050555
-
Forging a signature of in vivo senescence
-
Sharpless N.E., Sherr C.J. Forging a signature of in vivo senescence. Nat Rev Cancer 2015, 15(7):397-408.
-
(2015)
Nat Rev Cancer
, vol.15
, Issue.7
, pp. 397-408
-
-
Sharpless, N.E.1
Sherr, C.J.2
-
17
-
-
33748521288
-
Senescence in human intervertebral discs
-
Roberts S., Evans E.H., Kletsas D., Jaffray D.C., Eisenstein S.M. Senescence in human intervertebral discs. Eur Spine J 2006, 15(Suppl 3):S312-S316.
-
(2006)
Eur Spine J
, vol.15
, pp. S312-S316
-
-
Roberts, S.1
Evans, E.H.2
Kletsas, D.3
Jaffray, D.C.4
Eisenstein, S.M.5
-
18
-
-
67651083411
-
Senescence mechanisms of nucleus pulposus chondrocytes in human intervertebral discs
-
Kim K.W., Chung H.N., Ha K.Y., Lee J.S., Kim Y.Y. Senescence mechanisms of nucleus pulposus chondrocytes in human intervertebral discs. Spine J 2009, 9(8):658-666.
-
(2009)
Spine J
, vol.9
, Issue.8
, pp. 658-666
-
-
Kim, K.W.1
Chung, H.N.2
Ha, K.Y.3
Lee, J.S.4
Kim, Y.Y.5
-
19
-
-
33846652876
-
Senescence in cells of the aging and degenerating intervertebral disc: immunolocalization of senescence-associated beta-galactosidase in human and sand rat discs
-
Gruber H.E., Ingram J.A., Norton H.J., Hanley E.N. Senescence in cells of the aging and degenerating intervertebral disc: immunolocalization of senescence-associated beta-galactosidase in human and sand rat discs. Spine (Phila Pa 1976) 2007, 32(3):321-327.
-
(2007)
Spine (Phila Pa 1976)
, vol.32
, Issue.3
, pp. 321-327
-
-
Gruber, H.E.1
Ingram, J.A.2
Norton, H.J.3
Hanley, E.N.4
-
20
-
-
13944270339
-
Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors
-
Campisi J. Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors. Cell 2005, 120(4):513-522.
-
(2005)
Cell
, vol.120
, Issue.4
, pp. 513-522
-
-
Campisi, J.1
-
21
-
-
77954563804
-
Senescent cells as a source of inflammatory factors for tumor progression
-
Davalos A.R., Coppe J.P., Campisi J., Desprez P.Y. Senescent cells as a source of inflammatory factors for tumor progression. Cancer Metastasis Rev 2010, 29(2):273-283.
-
(2010)
Cancer Metastasis Rev
, vol.29
, Issue.2
, pp. 273-283
-
-
Davalos, A.R.1
Coppe, J.P.2
Campisi, J.3
Desprez, P.Y.4
-
22
-
-
67749114451
-
Senescent cells in the intervertebral disc: numbers and mechanisms
-
Kletsas D. Senescent cells in the intervertebral disc: numbers and mechanisms. Spine J 2009, 9(8):677-678.
-
(2009)
Spine J
, vol.9
, Issue.8
, pp. 677-678
-
-
Kletsas, D.1
-
23
-
-
67650383738
-
Aging and osteoarthritis: the role of chondrocyte senescence and aging changes in the cartilage matrix
-
Loeser R.F. Aging and osteoarthritis: the role of chondrocyte senescence and aging changes in the cartilage matrix. Osteoarthritis Cartilage 2009, 17(8):971-979.
-
(2009)
Osteoarthritis Cartilage
, vol.17
, Issue.8
, pp. 971-979
-
-
Loeser, R.F.1
-
24
-
-
34249788140
-
Accelerated cellular senescence in degenerate intervertebral discs: a possible role in the pathogenesis of intervertebral disc degeneration
-
Le M.C.L., Freemont A.J., Hoyland J.A. Accelerated cellular senescence in degenerate intervertebral discs: a possible role in the pathogenesis of intervertebral disc degeneration. Arthritis Res Ther 2007, 9(3):R45.
-
(2007)
Arthritis Res Ther
, vol.9
, Issue.3
, pp. R45
-
-
Le, M.C.L.1
Freemont, A.J.2
Hoyland, J.A.3
-
25
-
-
59749099570
-
IGF-1 rescues human intervertebral annulus cells from in vitro stress-induced premature senescence
-
Gruber H.E., Hoelscher G.L., Ingram J.A., Bethea S., Hanley E.N. IGF-1 rescues human intervertebral annulus cells from in vitro stress-induced premature senescence. Growth Factors 2008, 26(4):220-225.
-
(2008)
Growth Factors
, vol.26
, Issue.4
, pp. 220-225
-
-
Gruber, H.E.1
Hoelscher, G.L.2
Ingram, J.A.3
Bethea, S.4
Hanley, E.N.5
-
26
-
-
77957688083
-
Enhancement of intervertebral disc cell senescence by WNT/beta-catenin signaling-induced matrix metalloproteinase expression
-
Hiyama A., Sakai D., Risbud M.V., Tanaka M., Arai F., Abe K., et al. Enhancement of intervertebral disc cell senescence by WNT/beta-catenin signaling-induced matrix metalloproteinase expression. Arthritis Rheum 2010, 62(10):3036-3047.
-
(2010)
Arthritis Rheum
, vol.62
, Issue.10
, pp. 3036-3047
-
-
Hiyama, A.1
Sakai, D.2
Risbud, M.V.3
Tanaka, M.4
Arai, F.5
Abe, K.6
-
27
-
-
63649096684
-
Increased cell senescence is associated with decreased cell proliferation in vivo in the degenerating human annulus
-
Gruber H.E., Ingram J.A., Davis D.E., Hanley E.N. Increased cell senescence is associated with decreased cell proliferation in vivo in the degenerating human annulus. Spine J 2009, 9(3):210-215.
-
(2009)
Spine J
, vol.9
, Issue.3
, pp. 210-215
-
-
Gruber, H.E.1
Ingram, J.A.2
Davis, D.E.3
Hanley, E.N.4
-
28
-
-
84894451272
-
In vitro lifespan and senescence mechanisms of human nucleus pulposus chondrocytes
-
Jeong S.W., Lee J.S., Kim K.W. In vitro lifespan and senescence mechanisms of human nucleus pulposus chondrocytes. Spine J 2014, 14(3):499-504.
-
(2014)
Spine J
, vol.14
, Issue.3
, pp. 499-504
-
-
Jeong, S.W.1
Lee, J.S.2
Kim, K.W.3
-
29
-
-
50549099313
-
Caveolin-1 expression and stress-induced premature senescence in human intervertebral disc degeneration
-
Heathfield S.K., Le M.C.L., Hoyland J.A. Caveolin-1 expression and stress-induced premature senescence in human intervertebral disc degeneration. Arthritis Res Ther 2008, 10(4):R87.
-
(2008)
Arthritis Res Ther
, vol.10
, Issue.4
, pp. R87
-
-
Heathfield, S.K.1
Le, M.C.L.2
Hoyland, J.A.3
-
30
-
-
0034753182
-
Cell cluster formation in degenerate lumbar intervertebral discs is associated with increased disc cell proliferation
-
Johnson W.E., Eisenstein S.M., Roberts S. Cell cluster formation in degenerate lumbar intervertebral discs is associated with increased disc cell proliferation. Connect Tissue Res 2001, 42(3):197-207.
-
(2001)
Connect Tissue Res
, vol.42
, Issue.3
, pp. 197-207
-
-
Johnson, W.E.1
Eisenstein, S.M.2
Roberts, S.3
-
31
-
-
70450270932
-
Disc cell clusters in pathological human intervertebral discs are associated with increased stress protein immunostaining
-
Sharp C.A., Roberts S., Evans H., Brown S.J. Disc cell clusters in pathological human intervertebral discs are associated with increased stress protein immunostaining. Eur Spine J 2009, 18(11):1587-1594.
-
(2009)
Eur Spine J
, vol.18
, Issue.11
, pp. 1587-1594
-
-
Sharp, C.A.1
Roberts, S.2
Evans, H.3
Brown, S.J.4
-
32
-
-
14644410453
-
The signals and pathways activating cellular senescence
-
Ben-Porath I., Weinberg R.A. The signals and pathways activating cellular senescence. Int J Biochem Cell Biol 2005, 37(5):961-976.
-
(2005)
Int J Biochem Cell Biol
, vol.37
, Issue.5
, pp. 961-976
-
-
Ben-Porath, I.1
Weinberg, R.A.2
-
33
-
-
84889565689
-
Senescence is a developmental mechanism that contributes to embryonic growth and patterning
-
Storer M., Mas A., Robert-Moreno A., Pecoraro M., Ortells M.C., Di G.V., et al. Senescence is a developmental mechanism that contributes to embryonic growth and patterning. Cell 2013, 155(5):1119-1130.
-
(2013)
Cell
, vol.155
, Issue.5
, pp. 1119-1130
-
-
Storer, M.1
Mas, A.2
Robert-Moreno, A.3
Pecoraro, M.4
Ortells, M.C.5
Di, G.V.6
-
34
-
-
28844502298
-
Vertebral endplate architecture and vascularization: application of micro-computerized tomography, a vascular tracer, and immunocytochemistry in analyses of disc degeneration in the aging sand rat
-
Gruber H.E., Ashraf N., Kilburn J., Williams C., Norton H.J., Gordon B.E., et al. Vertebral endplate architecture and vascularization: application of micro-computerized tomography, a vascular tracer, and immunocytochemistry in analyses of disc degeneration in the aging sand rat. Spine (Phila Pa 1976) 2005, 30(23):2593-2600.
-
(2005)
Spine (Phila Pa 1976)
, vol.30
, Issue.23
, pp. 2593-2600
-
-
Gruber, H.E.1
Ashraf, N.2
Kilburn, J.3
Williams, C.4
Norton, H.J.5
Gordon, B.E.6
-
35
-
-
84902659050
-
Significance of hypoxia in the physiological function of intervertebral disc cells
-
Chen J.W., Li B., Yang Y.H., Jiang S.D., Jiang L.S. Significance of hypoxia in the physiological function of intervertebral disc cells. Crit Rev Eukaryot Gene Expr 2014, 24(3):193-204.
-
(2014)
Crit Rev Eukaryot Gene Expr
, vol.24
, Issue.3
, pp. 193-204
-
-
Chen, J.W.1
Li, B.2
Yang, Y.H.3
Jiang, S.D.4
Jiang, L.S.5
-
36
-
-
33748756124
-
TonEBP/OREBP is a regulator of nucleus pulposus cell function and survival in the intervertebral disc
-
Tsai T.T., Danielson K.G., Guttapalli A., Oguz E., Albert T.J., Shapiro I.M., et al. TonEBP/OREBP is a regulator of nucleus pulposus cell function and survival in the intervertebral disc. J Biol Chem 2006, 281(35):25416-25424.
-
(2006)
J Biol Chem
, vol.281
, Issue.35
, pp. 25416-25424
-
-
Tsai, T.T.1
Danielson, K.G.2
Guttapalli, A.3
Oguz, E.4
Albert, T.J.5
Shapiro, I.M.6
-
37
-
-
38749098170
-
Expression of acid-sensing ion channel 3 (ASIC3) in nucleus pulposus cells of the intervertebral disc is regulated by p75NTR and ERK signaling
-
Uchiyama Y., Cheng C.C., Danielson K.G., Mochida J., Albert T.J., Shapiro I.M., et al. Expression of acid-sensing ion channel 3 (ASIC3) in nucleus pulposus cells of the intervertebral disc is regulated by p75NTR and ERK signaling. J Bone Miner Res 2007, 22(12):1996-2006.
-
(2007)
J Bone Miner Res
, vol.22
, Issue.12
, pp. 1996-2006
-
-
Uchiyama, Y.1
Cheng, C.C.2
Danielson, K.G.3
Mochida, J.4
Albert, T.J.5
Shapiro, I.M.6
-
38
-
-
33645562103
-
Effects of mechanical loading on intervertebral disc metabolism in vivo
-
Iatridis J.C., MacLean J.J., Roughley P.J., Alini M. Effects of mechanical loading on intervertebral disc metabolism in vivo. J Bone Joint Surg Am 2006, 88(Suppl 2):41-46.
-
(2006)
J Bone Joint Surg Am
, vol.88
, pp. 41-46
-
-
Iatridis, J.C.1
MacLean, J.J.2
Roughley, P.J.3
Alini, M.4
-
39
-
-
78149283241
-
Leg amputation accelerates senescence of rat lumbar intervertebral discs
-
Xing Q.J., Liang Q.Q., Bian Q., Ding D.F., Cui X.J., Shi Q., et al. Leg amputation accelerates senescence of rat lumbar intervertebral discs. Spine (Phila Pa 1976) 2010, 35(23):E1253-E1261.
-
(2010)
Spine (Phila Pa 1976)
, vol.35
, Issue.23
, pp. E1253-E1261
-
-
Xing, Q.J.1
Liang, Q.Q.2
Bian, Q.3
Ding, D.F.4
Cui, X.J.5
Shi, Q.6
-
40
-
-
84883871280
-
Dynamic pressurization induces transition of notochordal cells to a mature phenotype while retaining production of important patterning ligands from development
-
Purmessur D., Guterl C.C., Cho S.K., Cornejo M.C., Lam Y.W., Ballif B.A., et al. Dynamic pressurization induces transition of notochordal cells to a mature phenotype while retaining production of important patterning ligands from development. Arthritis Res Ther 2013, 15(5):R122.
-
(2013)
Arthritis Res Ther
, vol.15
, Issue.5
, pp. R122
-
-
Purmessur, D.1
Guterl, C.C.2
Cho, S.K.3
Cornejo, M.C.4
Lam, Y.W.5
Ballif, B.A.6
-
41
-
-
84958115255
-
SIRT1 plays a protective role in intervertebral disc degeneration in a puncture-induced rodent model
-
Xia X., Guo J., Lu F., Jiang J. SIRT1 plays a protective role in intervertebral disc degeneration in a puncture-induced rodent model. Spine (Phila Pa 1976) 2015, 40(9):E515-E524.
-
(2015)
Spine (Phila Pa 1976)
, vol.40
, Issue.9
, pp. E515-E524
-
-
Xia, X.1
Guo, J.2
Lu, F.3
Jiang, J.4
-
42
-
-
84908664978
-
Oxidative stress participates in age-related changes in rat lumbar intervertebral discs
-
Hou G., Lu H., Chen M., Yao H., Zhao H. Oxidative stress participates in age-related changes in rat lumbar intervertebral discs. Arch Gerontol Geriatr 2014, 59(3):665-669.
-
(2014)
Arch Gerontol Geriatr
, vol.59
, Issue.3
, pp. 665-669
-
-
Hou, G.1
Lu, H.2
Chen, M.3
Yao, H.4
Zhao, H.5
-
43
-
-
84878203794
-
Mitochondrial-derived reactive oxygen species (ROS) play a causal role in aging-related intervertebral disc degeneration
-
Nasto L.A., Robinson A.R., Ngo K., Clauson C.L., Dong Q., St C.C., et al. Mitochondrial-derived reactive oxygen species (ROS) play a causal role in aging-related intervertebral disc degeneration. J Orthop Res 2013, 31(7):1150-1157.
-
(2013)
J Orthop Res
, vol.31
, Issue.7
, pp. 1150-1157
-
-
Nasto, L.A.1
Robinson, A.R.2
Ngo, K.3
Clauson, C.L.4
Dong, Q.5
St, C.C.6
-
44
-
-
84904559661
-
Accelerated premature stress-induced senescence of young annulus fibrosus cells of rats by high glucose-induced oxidative stress
-
Park J.S., Park J.B., Park I.J., Park E.Y. Accelerated premature stress-induced senescence of young annulus fibrosus cells of rats by high glucose-induced oxidative stress. Int Orthop 2014, 38(6):1311-1320.
-
(2014)
Int Orthop
, vol.38
, Issue.6
, pp. 1311-1320
-
-
Park, J.S.1
Park, J.B.2
Park, I.J.3
Park, E.Y.4
-
45
-
-
84875214991
-
Apoptosis, senescence, and autophagy in rat nucleus pulposus cells: implications for diabetic intervertebral disc degeneration
-
Jiang L., Zhang X., Zheng X., Ru A., Ni X., Wu Y., et al. Apoptosis, senescence, and autophagy in rat nucleus pulposus cells: implications for diabetic intervertebral disc degeneration. J Orthop Res 2013, 31(5):692-702.
-
(2013)
J Orthop Res
, vol.31
, Issue.5
, pp. 692-702
-
-
Jiang, L.1
Zhang, X.2
Zheng, X.3
Ru, A.4
Ni, X.5
Wu, Y.6
-
46
-
-
84862997587
-
Spine degeneration in a murine model of chronic human tobacco smokers
-
Wang D., Nasto L.A., Roughley P., Leme A.S., Houghton A.M., Usas A., et al. Spine degeneration in a murine model of chronic human tobacco smokers. Osteoarthritis Cartilage 2012, 20(8):896-905.
-
(2012)
Osteoarthritis Cartilage
, vol.20
, Issue.8
, pp. 896-905
-
-
Wang, D.1
Nasto, L.A.2
Roughley, P.3
Leme, A.S.4
Houghton, A.M.5
Usas, A.6
-
47
-
-
84894425812
-
Investigating the role of DNA damage in tobacco smoking-induced spine degeneration
-
Nasto L.A., Ngo K., Leme A.S., Robinson A.R., Dong Q., Roughley P., et al. Investigating the role of DNA damage in tobacco smoking-induced spine degeneration. Spine J 2014, 14(3):416-423.
-
(2014)
Spine J
, vol.14
, Issue.3
, pp. 416-423
-
-
Nasto, L.A.1
Ngo, K.2
Leme, A.S.3
Robinson, A.R.4
Dong, Q.5
Roughley, P.6
-
48
-
-
84860442850
-
The association of lumbar intervertebral disc degeneration on magnetic resonance imaging with body mass index in overweight and obese adults: a population-based study
-
Samartzis D., Karppinen J., Chan D., Luk K.D., Cheung K.M. The association of lumbar intervertebral disc degeneration on magnetic resonance imaging with body mass index in overweight and obese adults: a population-based study. Arthritis Rheum 2012, 64(5):1488-1496.
-
(2012)
Arthritis Rheum
, vol.64
, Issue.5
, pp. 1488-1496
-
-
Samartzis, D.1
Karppinen, J.2
Chan, D.3
Luk, K.D.4
Cheung, K.M.5
-
49
-
-
34548506785
-
Heritability of low back pain and the role of disc degeneration
-
Battie M.C., Videman T., Levalahti E., Gill K., Kaprio J. Heritability of low back pain and the role of disc degeneration. Pain 2007, 131(3):272-280.
-
(2007)
Pain
, vol.131
, Issue.3
, pp. 272-280
-
-
Battie, M.C.1
Videman, T.2
Levalahti, E.3
Gill, K.4
Kaprio, J.5
-
50
-
-
39049091805
-
Telomerase, senescence and ageing
-
Shawi M., Autexier C. Telomerase, senescence and ageing. Mech Ageing Dev 2008, 129(1-2):3-10.
-
(2008)
Mech Ageing Dev
, vol.129
, Issue.1-2
, pp. 3-10
-
-
Shawi, M.1
Autexier, C.2
-
51
-
-
14844362721
-
ISSLS prize winner: a study of diffusion in human lumbar discs: a serial magnetic resonance imaging study documenting the influence of the endplate on diffusion in normal and degenerate discs
-
Rajasekaran S., Babu J.N., Arun R., Armstrong B.R., Shetty A.P., Murugan S. ISSLS prize winner: a study of diffusion in human lumbar discs: a serial magnetic resonance imaging study documenting the influence of the endplate on diffusion in normal and degenerate discs. Spine (Phila Pa 1976) 2004, 29(23):2654-2667.
-
(2004)
Spine (Phila Pa 1976)
, vol.29
, Issue.23
, pp. 2654-2667
-
-
Rajasekaran, S.1
Babu, J.N.2
Arun, R.3
Armstrong, B.R.4
Shetty, A.P.5
Murugan, S.6
-
52
-
-
80053183939
-
Intervertebral disk nutrition: a review of factors influencing concentrations of nutrients and metabolites
-
Grunhagen T., Shirazi-Adl A., Fairbank J.C., Urban J.P. Intervertebral disk nutrition: a review of factors influencing concentrations of nutrients and metabolites. Orthop Clin North Am 2011, 42(4):465-477.
-
(2011)
Orthop Clin North Am
, vol.42
, Issue.4
, pp. 465-477
-
-
Grunhagen, T.1
Shirazi-Adl, A.2
Fairbank, J.C.3
Urban, J.P.4
-
53
-
-
33646010313
-
Nucleus pulposus cells express HIF-1 alpha under normoxic culture conditions: a metabolic adaptation to the intervertebral disc microenvironment
-
Risbud M.V., Guttapalli A., Stokes D.G., Hawkins D., Danielson K.G., Schaer T.P., et al. Nucleus pulposus cells express HIF-1 alpha under normoxic culture conditions: a metabolic adaptation to the intervertebral disc microenvironment. J Cell Biochem 2006, 98(1):152-159.
-
(2006)
J Cell Biochem
, vol.98
, Issue.1
, pp. 152-159
-
-
Risbud, M.V.1
Guttapalli, A.2
Stokes, D.G.3
Hawkins, D.4
Danielson, K.G.5
Schaer, T.P.6
-
54
-
-
84856160786
-
HIF-1alpha and HIF-2alpha degradation is differentially regulated in nucleus pulposus cells of the intervertebral disc
-
Fujita N., Chiba K., Shapiro I.M., Risbud M.V. HIF-1alpha and HIF-2alpha degradation is differentially regulated in nucleus pulposus cells of the intervertebral disc. J Bone Miner Res 2012, 27(2):401-412.
-
(2012)
J Bone Miner Res
, vol.27
, Issue.2
, pp. 401-412
-
-
Fujita, N.1
Chiba, K.2
Shapiro, I.M.3
Risbud, M.V.4
-
55
-
-
44249119586
-
The influence of serum, glucose and oxygen on intervertebral disc cell growth in vitro: implications for degenerative disc disease
-
Johnson W.E., Stephan S., Roberts S. The influence of serum, glucose and oxygen on intervertebral disc cell growth in vitro: implications for degenerative disc disease. Arthritis Res Ther 2008, 10(2):R46.
-
(2008)
Arthritis Res Ther
, vol.10
, Issue.2
, pp. R46
-
-
Johnson, W.E.1
Stephan, S.2
Roberts, S.3
-
56
-
-
33847385469
-
In situ oxygen utilization in the rat intervertebral disc
-
Lee D.C., Adams C.S., Albert T.J., Shapiro I.M., Evans S.M., Koch C.J. In situ oxygen utilization in the rat intervertebral disc. J Anat 2007, 210(3):294-303.
-
(2007)
J Anat
, vol.210
, Issue.3
, pp. 294-303
-
-
Lee, D.C.1
Adams, C.S.2
Albert, T.J.3
Shapiro, I.M.4
Evans, S.M.5
Koch, C.J.6
-
57
-
-
14844350606
-
Growth factors and treatment of intervertebral disc degeneration
-
Masuda K., Oegema T.R., An H.S. Growth factors and treatment of intervertebral disc degeneration. Spine (Phila Pa 1976) 2004, 29(23):2757-2769.
-
(2004)
Spine (Phila Pa 1976)
, vol.29
, Issue.23
, pp. 2757-2769
-
-
Masuda, K.1
Oegema, T.R.2
An, H.S.3
-
58
-
-
0029049874
-
Effect of disk maturation on diffusion of low-molecular-weight gadolinium complexes: an experimental study in rabbits
-
Ibrahim M.A., Haughton V.M., Hyde J.S. Effect of disk maturation on diffusion of low-molecular-weight gadolinium complexes: an experimental study in rabbits. AJNR Am J Neuroradiol 1995, 16(6):1307-1311.
-
(1995)
AJNR Am J Neuroradiol
, vol.16
, Issue.6
, pp. 1307-1311
-
-
Ibrahim, M.A.1
Haughton, V.M.2
Hyde, J.S.3
-
59
-
-
84905400560
-
Mechanical loading of the intervertebral disc: from the macroscopic to the cellular level
-
Neidlinger-Wilke C., Galbusera F., Pratsinis H., Mavrogonatou E., Mietsch A., Kletsas D., et al. Mechanical loading of the intervertebral disc: from the macroscopic to the cellular level. Eur Spine J 2014, 23(Suppl 3):S333-S343.
-
(2014)
Eur Spine J
, vol.23
, pp. S333-S343
-
-
Neidlinger-Wilke, C.1
Galbusera, F.2
Pratsinis, H.3
Mavrogonatou, E.4
Mietsch, A.5
Kletsas, D.6
-
60
-
-
84930822168
-
Mechanics and biology in intervertebral disc degeneration: a vicious circle
-
Vergroesen P.P., Kingma I., Emanuel K.S., Hoogendoorn R.J., Welting T.J., van Royen B.J., et al. Mechanics and biology in intervertebral disc degeneration: a vicious circle. Osteoarthritis Cartilage 2015, 23(7):1057-1070.
-
(2015)
Osteoarthritis Cartilage
, vol.23
, Issue.7
, pp. 1057-1070
-
-
Vergroesen, P.P.1
Kingma, I.2
Emanuel, K.S.3
Hoogendoorn, R.J.4
Welting, T.J.5
van Royen, B.J.6
-
61
-
-
4844225379
-
Anabolic and catabolic mRNA levels of the intervertebral disc vary with the magnitude and frequency of in vivo dynamic compression
-
Maclean J.J., Lee C.R., Alini M., Iatridis J.C. Anabolic and catabolic mRNA levels of the intervertebral disc vary with the magnitude and frequency of in vivo dynamic compression. J Orthop Res 2004, 22(6):1193-1200.
-
(2004)
J Orthop Res
, vol.22
, Issue.6
, pp. 1193-1200
-
-
Maclean, J.J.1
Lee, C.R.2
Alini, M.3
Iatridis, J.C.4
-
62
-
-
0742269711
-
Biological response of the intervertebral disc to dynamic loading
-
Walsh A.J., Lotz J.C. Biological response of the intervertebral disc to dynamic loading. J Biomech 2004, 37(3):329-337.
-
(2004)
J Biomech
, vol.37
, Issue.3
, pp. 329-337
-
-
Walsh, A.J.1
Lotz, J.C.2
-
63
-
-
68849089477
-
In vivo remodeling of intervertebral discs in response to short- and long-term dynamic compression
-
Wuertz K., Godburn K., MacLean J.J., Barbir A., Donnelly J.S., Roughley P.J., et al. In vivo remodeling of intervertebral discs in response to short- and long-term dynamic compression. J Orthop Res 2009, 27(9):1235-1242.
-
(2009)
J Orthop Res
, vol.27
, Issue.9
, pp. 1235-1242
-
-
Wuertz, K.1
Godburn, K.2
MacLean, J.J.3
Barbir, A.4
Donnelly, J.S.5
Roughley, P.J.6
-
64
-
-
84883161140
-
Region specific response of intervertebral disc cells to complex dynamic loading: an organ culture study using a dynamic torsion-compression bioreactor
-
Chan S.C., Walser J., Kappeli P., Shamsollahi M.J., Ferguson S.J., Gantenbein-Ritter B. Region specific response of intervertebral disc cells to complex dynamic loading: an organ culture study using a dynamic torsion-compression bioreactor. PLoS One 2013, 8(8):e72489.
-
(2013)
PLoS One
, vol.8
, Issue.8
-
-
Chan, S.C.1
Walser, J.2
Kappeli, P.3
Shamsollahi, M.J.4
Ferguson, S.J.5
Gantenbein-Ritter, B.6
-
65
-
-
79960340632
-
Complex loading affects intervertebral disc mechanics and biology
-
Walter B.A., Korecki C.L., Purmessur D., Roughley P.J., Michalek A.J., Iatridis J.C. Complex loading affects intervertebral disc mechanics and biology. Osteoarthritis Cartilage 2011, 19(8):1011-1018.
-
(2011)
Osteoarthritis Cartilage
, vol.19
, Issue.8
, pp. 1011-1018
-
-
Walter, B.A.1
Korecki, C.L.2
Purmessur, D.3
Roughley, P.J.4
Michalek, A.J.5
Iatridis, J.C.6
-
66
-
-
0035216307
-
Intervertebral disc herniation: studies on a porcine model exposed to highly repetitive flexion/extension motion with compressive force
-
Callaghan J.P., McGill S.M. Intervertebral disc herniation: studies on a porcine model exposed to highly repetitive flexion/extension motion with compressive force. Clin Biomech (Bristol, Avon) 2001, 16(1):28-37.
-
(2001)
Clin Biomech (Bristol, Avon)
, vol.16
, Issue.1
, pp. 28-37
-
-
Callaghan, J.P.1
McGill, S.M.2
-
67
-
-
55449106580
-
Prolonged upright posture induces degenerative changes in intervertebral discs in rat lumbar spine
-
Liang Q.Q., Zhou Q., Zhang M., Hou W., Cui X.J., Li C.G., et al. Prolonged upright posture induces degenerative changes in intervertebral discs in rat lumbar spine. Spine (Phila Pa 1976) 2008, 33(19):2052-2058.
-
(2008)
Spine (Phila Pa 1976)
, vol.33
, Issue.19
, pp. 2052-2058
-
-
Liang, Q.Q.1
Zhou, Q.2
Zhang, M.3
Hou, W.4
Cui, X.J.5
Li, C.G.6
-
68
-
-
77956911828
-
The influence of torsion on disc herniation when combined with flexion
-
Veres S.P., Robertson P.A., Broom N.D. The influence of torsion on disc herniation when combined with flexion. Eur Spine J 2010, 19(9):1468-1478.
-
(2010)
Eur Spine J
, vol.19
, Issue.9
, pp. 1468-1478
-
-
Veres, S.P.1
Robertson, P.A.2
Broom, N.D.3
-
69
-
-
27744457462
-
The influence of static axial torque in combined loading on intervertebral joint failure mechanics using a porcine model
-
Drake J.D., Aultman C.D., McGill S.M., Callaghan J.P. The influence of static axial torque in combined loading on intervertebral joint failure mechanics using a porcine model. Clin Biomech (Bristol, Avon) 2005, 20(10):1038-1045.
-
(2005)
Clin Biomech (Bristol, Avon)
, vol.20
, Issue.10
, pp. 1038-1045
-
-
Drake, J.D.1
Aultman, C.D.2
McGill, S.M.3
Callaghan, J.P.4
-
70
-
-
84902298640
-
How healthy discs herniate: a biomechanical and microstructural study investigating the combined effects of compression rate and flexion
-
Wade K.R., Robertson P.A., Thambyah A., Broom N.D. How healthy discs herniate: a biomechanical and microstructural study investigating the combined effects of compression rate and flexion. Spine (Phila Pa 1976) 2014, 39(13):1018-1028.
-
(2014)
Spine (Phila Pa 1976)
, vol.39
, Issue.13
, pp. 1018-1028
-
-
Wade, K.R.1
Robertson, P.A.2
Thambyah, A.3
Broom, N.D.4
-
71
-
-
84907855721
-
Acute mechanical injury of the human intervertebral disc: link to degeneration and pain
-
discussion 110-1
-
Alkhatib B., Rosenzweig D.H., Krock E., Roughley P.J., Beckman L., Steffen T., et al. Acute mechanical injury of the human intervertebral disc: link to degeneration and pain. Eur Cell Mater 2014, 28:98-110. discussion 110-1.
-
(2014)
Eur Cell Mater
, vol.28
, pp. 98-110
-
-
Alkhatib, B.1
Rosenzweig, D.H.2
Krock, E.3
Roughley, P.J.4
Beckman, L.5
Steffen, T.6
-
72
-
-
84892715888
-
High mechanical strain of primary intervertebral disc cells promotes secretion of inflammatory factors associated with disc degeneration and pain
-
Gawri R., Rosenzweig D.H., Krock E., Ouellet J.A., Stone L.S., Quinn T.M., et al. High mechanical strain of primary intervertebral disc cells promotes secretion of inflammatory factors associated with disc degeneration and pain. Arthritis Res Ther 2014, 16(1):R21.
-
(2014)
Arthritis Res Ther
, vol.16
, Issue.1
, pp. R21
-
-
Gawri, R.1
Rosenzweig, D.H.2
Krock, E.3
Ouellet, J.A.4
Stone, L.S.5
Quinn, T.M.6
-
73
-
-
58249144848
-
Inflammatory signaling and cellular senescence
-
Ren J.L., Pan J.S., Lu Y.P., Sun P., Han J. Inflammatory signaling and cellular senescence. Cell Signal 2009, 21(3):378-383.
-
(2009)
Cell Signal
, vol.21
, Issue.3
, pp. 378-383
-
-
Ren, J.L.1
Pan, J.S.2
Lu, Y.P.3
Sun, P.4
Han, J.5
-
74
-
-
8644230190
-
Degenerative mechanics of the lumbar spine
-
Niosi C.A., Oxland T.R. Degenerative mechanics of the lumbar spine. Spine J 2004, 4(6 Suppl):202S-208S.
-
(2004)
Spine J
, vol.4
, Issue.6
, pp. 202S-208S
-
-
Niosi, C.A.1
Oxland, T.R.2
-
75
-
-
81255134289
-
Effect of orientation and targeted extracellular matrix degradation on the shear mechanical properties of the annulus fibrosus
-
Jacobs N.T., Smith L.J., Han W.M., Morelli J., Yoder J.H., Elliott D.M. Effect of orientation and targeted extracellular matrix degradation on the shear mechanical properties of the annulus fibrosus. J Mech Behav Biomed Mater 2011, 4(8):1611-1619.
-
(2011)
J Mech Behav Biomed Mater
, vol.4
, Issue.8
, pp. 1611-1619
-
-
Jacobs, N.T.1
Smith, L.J.2
Han, W.M.3
Morelli, J.4
Yoder, J.H.5
Elliott, D.M.6
-
76
-
-
84872831222
-
Genotoxic stress accelerates age-associated degenerative changes in intervertebral discs
-
Nasto L.A., Wang D., Robinson A.R., Clauson C.L., Ngo K., Dong Q., et al. Genotoxic stress accelerates age-associated degenerative changes in intervertebral discs. Mech Ageing Dev 2013, 134(1-2):35-42.
-
(2013)
Mech Ageing Dev
, vol.134
, Issue.1-2
, pp. 35-42
-
-
Nasto, L.A.1
Wang, D.2
Robinson, A.R.3
Clauson, C.L.4
Ngo, K.5
Dong, Q.6
-
77
-
-
84918554285
-
Extracellular osmolarity regulates matrix homeostasis in the intervertebral disc and articular cartilage: evolving role of TonEBP
-
Johnson Z.I., Shapiro I.M., Risbud M.V. Extracellular osmolarity regulates matrix homeostasis in the intervertebral disc and articular cartilage: evolving role of TonEBP. Matrix Biol 2014, 40:10-16.
-
(2014)
Matrix Biol
, vol.40
, pp. 10-16
-
-
Johnson, Z.I.1
Shapiro, I.M.2
Risbud, M.V.3
-
78
-
-
67650577141
-
High osmolality activates the G1 and G2 cell cycle checkpoints and affects the DNA integrity of nucleus pulposus intervertebral disc cells triggering an enhanced DNA repair response
-
Mavrogonatou E., Kletsas D. High osmolality activates the G1 and G2 cell cycle checkpoints and affects the DNA integrity of nucleus pulposus intervertebral disc cells triggering an enhanced DNA repair response. DNA Repair (Amst) 2009, 8(8):930-943.
-
(2009)
DNA Repair (Amst)
, vol.8
, Issue.8
, pp. 930-943
-
-
Mavrogonatou, E.1
Kletsas, D.2
-
79
-
-
58949103806
-
Characterization of intervertebral disc aging: longitudinal analysis of a rabbit model by magnetic resonance imaging, histology, and gene expression
-
Sowa G., Vadala G., Studer R., Kompel J., Iucu C., Georgescu H., et al. Characterization of intervertebral disc aging: longitudinal analysis of a rabbit model by magnetic resonance imaging, histology, and gene expression. Spine (Phila Pa 1976) 2008, 33(17):1821-1828.
-
(2008)
Spine (Phila Pa 1976)
, vol.33
, Issue.17
, pp. 1821-1828
-
-
Sowa, G.1
Vadala, G.2
Studer, R.3
Kompel, J.4
Iucu, C.5
Georgescu, H.6
-
80
-
-
43049163718
-
Free radicals and senescence
-
Lu T., Finkel T. Free radicals and senescence. Exp Cell Res 2008, 314(9):1918-1922.
-
(2008)
Exp Cell Res
, vol.314
, Issue.9
, pp. 1918-1922
-
-
Lu, T.1
Finkel, T.2
-
81
-
-
84888857607
-
Autophagy is activated in compression-induced cell degeneration and is mediated by reactive oxygen species in nucleus pulposus cells exposed to compression
-
Ma K.G., Shao Z.W., Yang S.H., Wang J., Wang B.C., Xiong L.M., et al. Autophagy is activated in compression-induced cell degeneration and is mediated by reactive oxygen species in nucleus pulposus cells exposed to compression. Osteoarthritis Cartilage 2013, 21(12):2030-2038.
-
(2013)
Osteoarthritis Cartilage
, vol.21
, Issue.12
, pp. 2030-2038
-
-
Ma, K.G.1
Shao, Z.W.2
Yang, S.H.3
Wang, J.4
Wang, B.C.5
Xiong, L.M.6
-
82
-
-
84862793462
-
Role of mitochondrial pathway in compression-induced apoptosis of nucleus pulposus cells
-
Ding F., Shao Z.W., Yang S.H., Wu Q., Gao F., Xiong L.M. Role of mitochondrial pathway in compression-induced apoptosis of nucleus pulposus cells. Apoptosis 2012, 17(6):579-590.
-
(2012)
Apoptosis
, vol.17
, Issue.6
, pp. 579-590
-
-
Ding, F.1
Shao, Z.W.2
Yang, S.H.3
Wu, Q.4
Gao, F.5
Xiong, L.M.6
-
83
-
-
84899452308
-
Telomeres, oxidative stress and inflammatory factors: partners in cellular senescence
-
Correia-Melo C., Hewitt G., Passos J.F. Telomeres, oxidative stress and inflammatory factors: partners in cellular senescence. Longev Healthspan 2014, 3(1):1.
-
(2014)
Longev Healthspan
, vol.3
, Issue.1
, pp. 1
-
-
Correia-Melo, C.1
Hewitt, G.2
Passos, J.F.3
-
84
-
-
84887459924
-
Redox control of the senescence regulator interleukin-1alpha and the secretory phenotype
-
McCarthy D.A., Clark R.R., Bartling T.R., Trebak M., Melendez J.A. Redox control of the senescence regulator interleukin-1alpha and the secretory phenotype. J Biol Chem 2013, 288(45):32149-32159.
-
(2013)
J Biol Chem
, vol.288
, Issue.45
, pp. 32149-32159
-
-
McCarthy, D.A.1
Clark, R.R.2
Bartling, T.R.3
Trebak, M.4
Melendez, J.A.5
-
85
-
-
84881399206
-
A complex secretory program orchestrated by the inflammasome controls paracrine senescence
-
Acosta J.C., Banito A., Wuestefeld T., Georgilis A., Janich P., Morton J.P., et al. A complex secretory program orchestrated by the inflammasome controls paracrine senescence. Nat Cell Biol 2013, 15(8):978-990.
-
(2013)
Nat Cell Biol
, vol.15
, Issue.8
, pp. 978-990
-
-
Acosta, J.C.1
Banito, A.2
Wuestefeld, T.3
Georgilis, A.4
Janich, P.5
Morton, J.P.6
-
86
-
-
84887345656
-
A complex interaction between Wnt signaling and TNF-alpha in nucleus pulposus cells
-
Hiyama A., Yokoyama K., Nukaga T., Sakai D., Mochida J. A complex interaction between Wnt signaling and TNF-alpha in nucleus pulposus cells. Arthritis Res Ther 2013, 15(6):R189.
-
(2013)
Arthritis Res Ther
, vol.15
, Issue.6
, pp. R189
-
-
Hiyama, A.1
Yokoyama, K.2
Nukaga, T.3
Sakai, D.4
Mochida, J.5
-
87
-
-
34248357202
-
Microarray analysis of laser capture microdissected-anulus cells from the human intervertebral disc
-
Gruber H.E., Mougeot J.L., Hoelscher G., Ingram J.A., Hanley E.N. Microarray analysis of laser capture microdissected-anulus cells from the human intervertebral disc. Spine (Phila Pa 1976) 2007, 32(11):1181-1187.
-
(2007)
Spine (Phila Pa 1976)
, vol.32
, Issue.11
, pp. 1181-1187
-
-
Gruber, H.E.1
Mougeot, J.L.2
Hoelscher, G.3
Ingram, J.A.4
Hanley, E.N.5
-
88
-
-
77649122081
-
Senescent vs. non-senescent cells in the human annulus in vivo: cell harvest with laser capture microdissection and gene expression studies with microarray analysis
-
Gruber H.E., Hoelscher G.L., Ingram J.A., Zinchenko N., Hanley E.N. Senescent vs. non-senescent cells in the human annulus in vivo: cell harvest with laser capture microdissection and gene expression studies with microarray analysis. BMC Biotechnol 2010, 10:5.
-
(2010)
BMC Biotechnol
, vol.10
, pp. 5
-
-
Gruber, H.E.1
Hoelscher, G.L.2
Ingram, J.A.3
Zinchenko, N.4
Hanley, E.N.5
-
89
-
-
84889802479
-
The cytokine and chemokine expression profile of nucleus pulposus cells: implications for degeneration and regeneration of the intervertebral disc
-
Phillips K.L., Chiverton N., Michael A.L., Cole A.A., Breakwell L.M., Haddock G., et al. The cytokine and chemokine expression profile of nucleus pulposus cells: implications for degeneration and regeneration of the intervertebral disc. Arthritis Res Ther 2013, 15(6):R213.
-
(2013)
Arthritis Res Ther
, vol.15
, Issue.6
, pp. R213
-
-
Phillips, K.L.1
Chiverton, N.2
Michael, A.L.3
Cole, A.A.4
Breakwell, L.M.5
Haddock, G.6
-
90
-
-
84860326883
-
Support of concept that migrating progenitor cells from stem cell niches contribute to normal regeneration of the adult mammal intervertebral disc: a descriptive study in the New Zealand white rabbit
-
Henriksson H.B., Svala E., Skioldebrand E., Lindahl A., Brisby H. Support of concept that migrating progenitor cells from stem cell niches contribute to normal regeneration of the adult mammal intervertebral disc: a descriptive study in the New Zealand white rabbit. Spine (Phila Pa 1976) 2012, 37(9):722-732.
-
(2012)
Spine (Phila Pa 1976)
, vol.37
, Issue.9
, pp. 722-732
-
-
Henriksson, H.B.1
Svala, E.2
Skioldebrand, E.3
Lindahl, A.4
Brisby, H.5
-
91
-
-
84930381177
-
Migration of bone marrow-derived cells for endogenous repair in a new tail-looping disc degeneration model in the mouse: a pilot study
-
Sakai D., Nishimura K., Tanaka M., Nakajima D., Grad S., Alini M., et al. Migration of bone marrow-derived cells for endogenous repair in a new tail-looping disc degeneration model in the mouse: a pilot study. Spine J 2015, 15(6):1356-1365.
-
(2015)
Spine J
, vol.15
, Issue.6
, pp. 1356-1365
-
-
Sakai, D.1
Nishimura, K.2
Tanaka, M.3
Nakajima, D.4
Grad, S.5
Alini, M.6
-
92
-
-
84957849205
-
Viability, growth kinetics and stem cell markers of single and clustered cells in human intervertebral discs: implications for regenerative therapies
-
Turner S., Balain B., Caterson B., Morgan C., Roberts S. Viability, growth kinetics and stem cell markers of single and clustered cells in human intervertebral discs: implications for regenerative therapies. Eur Spine J 2014, 23(11):2462-2472.
-
(2014)
Eur Spine J
, vol.23
, Issue.11
, pp. 2462-2472
-
-
Turner, S.1
Balain, B.2
Caterson, B.3
Morgan, C.4
Roberts, S.5
-
93
-
-
84930516015
-
The inflammatory milieu of the degenerate disc: is mesenchymal stem cell-based therapy for intervertebral disc repair a feasible approach?
-
Krock E., Rosenzweig D.H., Haglund L. The inflammatory milieu of the degenerate disc: is mesenchymal stem cell-based therapy for intervertebral disc repair a feasible approach?. Curr Stem Cell Res Ther 2015, 10(4):317-328.
-
(2015)
Curr Stem Cell Res Ther
, vol.10
, Issue.4
, pp. 317-328
-
-
Krock, E.1
Rosenzweig, D.H.2
Haglund, L.3
-
94
-
-
34248326042
-
Nucleus pulposus cellular longevity by telomerase gene therapy
-
Chung S.A., Wei A.Q., Connor D.E., Webb G.C., Molloy T., Pajic M., et al. Nucleus pulposus cellular longevity by telomerase gene therapy. Spine (Phila Pa 1976) 2007, 32(11):1188-1196.
-
(2007)
Spine (Phila Pa 1976)
, vol.32
, Issue.11
, pp. 1188-1196
-
-
Chung, S.A.1
Wei, A.Q.2
Connor, D.E.3
Webb, G.C.4
Molloy, T.5
Pajic, M.6
-
95
-
-
80053100194
-
Extending the activities of human nucleus pulposus cells with recombinant adeno-associated virus vector-mediated human telomerase reverse transcriptase gene transfer
-
Wu J., Wang D., Zhang C., Wang C., Zhang Y., Xin H., et al. Extending the activities of human nucleus pulposus cells with recombinant adeno-associated virus vector-mediated human telomerase reverse transcriptase gene transfer. Tissue Eng Part A 2011, 17(19-20):2407-2415.
-
(2011)
Tissue Eng Part A
, vol.17
, Issue.19-20
, pp. 2407-2415
-
-
Wu, J.1
Wang, D.2
Zhang, C.3
Wang, C.4
Zhang, Y.5
Xin, H.6
-
96
-
-
84859582048
-
Overexpression of hTERT extends replicative capacity of human nucleus pulposus cells, and protects against serum starvation-induced apoptosis and cell cycle arrest
-
Liang W., Ye D., Dai L., Shen Y., Xu J. Overexpression of hTERT extends replicative capacity of human nucleus pulposus cells, and protects against serum starvation-induced apoptosis and cell cycle arrest. J Cell Biochem 2012, 113(6):2112-2121.
-
(2012)
J Cell Biochem
, vol.113
, Issue.6
, pp. 2112-2121
-
-
Liang, W.1
Ye, D.2
Dai, L.3
Shen, Y.4
Xu, J.5
-
97
-
-
84888055764
-
Prolonged expansion of human nucleus pulposus cells expressing human telomerase reverse transcriptase mediated by lentiviral vector
-
Wu J., Wang D., Ruan D., He Q., Zhang Y., Wang C., et al. Prolonged expansion of human nucleus pulposus cells expressing human telomerase reverse transcriptase mediated by lentiviral vector. J Orthop Res 2014, 32(1):159-166.
-
(2014)
J Orthop Res
, vol.32
, Issue.1
, pp. 159-166
-
-
Wu, J.1
Wang, D.2
Ruan, D.3
He, Q.4
Zhang, Y.5
Wang, C.6
-
98
-
-
58149508954
-
Synergistic role of c-Myc and ERK1/2 in the mitogenic response to TGF beta-1 in cultured rat nucleus pulposus cells
-
Nakai T., Mochida J., Sakai D. Synergistic role of c-Myc and ERK1/2 in the mitogenic response to TGF beta-1 in cultured rat nucleus pulposus cells. Arthritis Res Ther 2008, 10(6):R140.
-
(2008)
Arthritis Res Ther
, vol.10
, Issue.6
, pp. R140
-
-
Nakai, T.1
Mochida, J.2
Sakai, D.3
-
99
-
-
79955047394
-
Accelerated epithelial cell senescence in IPF and the inhibitory role of SIRT6 in TGF-beta-induced senescence of human bronchial epithelial cells
-
Minagawa S., Araya J., Numata T., Nojiri S., Hara H., Yumino Y., et al. Accelerated epithelial cell senescence in IPF and the inhibitory role of SIRT6 in TGF-beta-induced senescence of human bronchial epithelial cells. Am J Physiol Lung Cell Mol Physiol 2011, 300(3):L391-L401.
-
(2011)
Am J Physiol Lung Cell Mol Physiol
, vol.300
, Issue.3
, pp. L391-L401
-
-
Minagawa, S.1
Araya, J.2
Numata, T.3
Nojiri, S.4
Hara, H.5
Yumino, Y.6
-
100
-
-
79951780686
-
The relationship between the Wnt/beta-catenin and TGF-beta/BMP signals in the intervertebral disc cell
-
Hiyama A., Sakai D., Tanaka M., Arai F., Nakajima D., Abe K., et al. The relationship between the Wnt/beta-catenin and TGF-beta/BMP signals in the intervertebral disc cell. J Cell Physiol 2011, 226(5):1139-1148.
-
(2011)
J Cell Physiol
, vol.226
, Issue.5
, pp. 1139-1148
-
-
Hiyama, A.1
Sakai, D.2
Tanaka, M.3
Arai, F.4
Nakajima, D.5
Abe, K.6
-
101
-
-
69249124009
-
Premature senescence of highly proliferative endothelial progenitor cells is induced by tumor necrosis factor-alpha via the p38 mitogen-activated protein kinase pathway
-
Zhang Y., Herbert B.S., Rajashekhar G., Ingram D.A., Yoder M.C., Clauss M., et al. Premature senescence of highly proliferative endothelial progenitor cells is induced by tumor necrosis factor-alpha via the p38 mitogen-activated protein kinase pathway. FASEB J 2009, 23(5):1358-1365.
-
(2009)
FASEB J
, vol.23
, Issue.5
, pp. 1358-1365
-
-
Zhang, Y.1
Herbert, B.S.2
Rajashekhar, G.3
Ingram, D.A.4
Yoder, M.C.5
Clauss, M.6
-
102
-
-
39049119345
-
P38 MAPK inhibition in nucleus pulposus cells: a potential target for treating intervertebral disc degeneration
-
Studer R.K., Aboka A.M., Gilbertson L.G., Georgescu H., Sowa G., Vo N., et al. p38 MAPK inhibition in nucleus pulposus cells: a potential target for treating intervertebral disc degeneration. Spine (Phila Pa 1976) 2007, 32(25):2827-2833.
-
(2007)
Spine (Phila Pa 1976)
, vol.32
, Issue.25
, pp. 2827-2833
-
-
Studer, R.K.1
Aboka, A.M.2
Gilbertson, L.G.3
Georgescu, H.4
Sowa, G.5
Vo, N.6
-
103
-
-
46449096413
-
P38 MAPK inhibition modulates rabbit nucleus pulposus cell response to IL-1
-
Studer R.K., Gilbertson L.G., Georgescu H., Sowa G., Vo N., Kang J.D. p38 MAPK inhibition modulates rabbit nucleus pulposus cell response to IL-1. J Orthop Res 2008, 26(7):991-998.
-
(2008)
J Orthop Res
, vol.26
, Issue.7
, pp. 991-998
-
-
Studer, R.K.1
Gilbertson, L.G.2
Georgescu, H.3
Sowa, G.4
Vo, N.5
Kang, J.D.6
-
104
-
-
84928243456
-
The Achilles' heel of senescent cells: from transcriptome to senolytic drugs
-
Zhu Y., Tchkonia T., Pirtskhalava T., Gower A.C., Ding H., Giorgadze N., et al. The Achilles' heel of senescent cells: from transcriptome to senolytic drugs. Aging Cell 2015, 14(4):644-658.
-
(2015)
Aging Cell
, vol.14
, Issue.4
, pp. 644-658
-
-
Zhu, Y.1
Tchkonia, T.2
Pirtskhalava, T.3
Gower, A.C.4
Ding, H.5
Giorgadze, N.6
-
105
-
-
84892772553
-
The transpedicular approach for the study of intervertebral disc regeneration strategies: in vivo characterization
-
Vadala G., De Strobel F., Bernardini M., Denaro L., D'Avella D., Denaro V. The transpedicular approach for the study of intervertebral disc regeneration strategies: in vivo characterization. Eur Spine J 2013, 22(Suppl 6):S972-S978.
-
(2013)
Eur Spine J
, vol.22
, pp. S972-S978
-
-
Vadala, G.1
De Strobel, F.2
Bernardini, M.3
Denaro, L.4
D'Avella, D.5
Denaro, V.6
-
106
-
-
84877855262
-
Combined anti-inflammatory and anti-AGE drug treatments have a protective effect on intervertebral discs in mice with diabetes
-
Illien-Junger S., Grosjean F., Laudier D.M., Vlassara H., Striker G.E., Iatridis J.C. Combined anti-inflammatory and anti-AGE drug treatments have a protective effect on intervertebral discs in mice with diabetes. PLoS One 2013, 8(5):e64302.
-
(2013)
PLoS One
, vol.8
, Issue.5
-
-
Illien-Junger, S.1
Grosjean, F.2
Laudier, D.M.3
Vlassara, H.4
Striker, G.E.5
Iatridis, J.C.6
-
107
-
-
84861821882
-
The impact of discography on the surgical decision in patients with chronic low back pain
-
Berg S., Isberg B., Josephson A., Fallman M. The impact of discography on the surgical decision in patients with chronic low back pain. Spine J 2012, 12(4):283-291.
-
(2012)
Spine J
, vol.12
, Issue.4
, pp. 283-291
-
-
Berg, S.1
Isberg, B.2
Josephson, A.3
Fallman, M.4
-
108
-
-
84861946126
-
Intradiscal pulsed radiofrequency application following provocative discography for the management of degenerative disc disease and concordant pain: a pilot study
-
Rohof O. Intradiscal pulsed radiofrequency application following provocative discography for the management of degenerative disc disease and concordant pain: a pilot study. Pain Pract 2012, 12(5):342-349.
-
(2012)
Pain Pract
, vol.12
, Issue.5
, pp. 342-349
-
-
Rohof, O.1
-
109
-
-
84882973099
-
The precision, accuracy and validity of detecting posterior ligamentous complex injuries of the thoracic and lumbar spine: a critical appraisal of the literature
-
van Middendorp J.J., Patel A.A., Schuetz M., Joaquim A.F. The precision, accuracy and validity of detecting posterior ligamentous complex injuries of the thoracic and lumbar spine: a critical appraisal of the literature. Eur Spine J 2013, 22(3):461-474.
-
(2013)
Eur Spine J
, vol.22
, Issue.3
, pp. 461-474
-
-
van Middendorp, J.J.1
Patel, A.A.2
Schuetz, M.3
Joaquim, A.F.4
-
110
-
-
84888007595
-
Adjacent segment disease in the lumbar spine following different treatment interventions
-
Radcliff K.E., Kepler C.K., Jakoi A., Sidhu G.S., Rihn J., Vaccaro A.R., et al. Adjacent segment disease in the lumbar spine following different treatment interventions. Spine J 2013, 13(10):1339-1349.
-
(2013)
Spine J
, vol.13
, Issue.10
, pp. 1339-1349
-
-
Radcliff, K.E.1
Kepler, C.K.2
Jakoi, A.3
Sidhu, G.S.4
Rihn, J.5
Vaccaro, A.R.6
-
111
-
-
84908507230
-
Comparison of adjacent segment disease after minimally invasive or open transforaminal lumbar interbody fusion
-
Yee T.J., Terman S.W., La Marca F., Park P. Comparison of adjacent segment disease after minimally invasive or open transforaminal lumbar interbody fusion. J Clin Neurosci 2014, 21(10):1796-1801.
-
(2014)
J Clin Neurosci
, vol.21
, Issue.10
, pp. 1796-1801
-
-
Yee, T.J.1
Terman, S.W.2
La Marca, F.3
Park, P.4
-
112
-
-
84926684490
-
Circumferential dynamic stabilization of the lumbar spine: a biomechanical analysis
-
Kafer W., Cakir B., Midderhoff S., Reichel H., Wilke H.J. Circumferential dynamic stabilization of the lumbar spine: a biomechanical analysis. Eur Spine J 2014, 23(11):2330-2339.
-
(2014)
Eur Spine J
, vol.23
, Issue.11
, pp. 2330-2339
-
-
Kafer, W.1
Cakir, B.2
Midderhoff, S.3
Reichel, H.4
Wilke, H.J.5
|