IGF-1 rescues human intervertebral annulus cells from in vitro stress-induced premature senescence

Growth Factors

Volumn 26, Issue 4, 2008, Pages 220-225

  Gruber, Helen E ^a   Hoelscher, Gretchen L ^a   Ingram, Jane A ^a   Bethea, Synthia ^a   Hanley, Edward N ^a  

^a CAROLINAS MEDICAL CENTER   (United States)

Author keywords

Cell senescence; Disc degeneration; Growth factors; IGF 1; Intervertebral disc; Senescence associated galactosidase

Indexed keywords

BETA GALACTOSIDASE; HYDROGEN PEROXIDE; SOMATOMEDIN C;

ANNULUS CELL; ARTICLE; BONE CELL; CELL AGING; CELL CULTURE; CELL STRESS; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; INTERVERTEBRAL DISK; PREMATURE AGING; PRIORITY JOURNAL; PROTEIN FUNCTION; SENESCENCE;

BETA-GALACTOSIDASE; CELL AGING; CELL CULTURE TECHNIQUES; CELLS, CULTURED; HUMANS; HYDROGEN PEROXIDE; IMMUNOHISTOCHEMISTRY; INSULIN-LIKE GROWTH FACTOR I; INTERVERTEBRAL DISK; OXIDANTS; OXIDATIVE STRESS; SPINAL DISEASES;

EID: 59749099570     PISSN: 08977194     EISSN: 10292292     Source Type: Journal    
DOI: 10.1080/08977190802273814     Document Type: Article

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