High mechanical strain of primary intervertebral disc cells promotes secretion of inflammatory factors associated with disc degeneration and pain

Arthritis Research and Therapy

Volumn 16, Issue 1, 2014, Pages

  Gawri, Rahul ^a   Rosenzweig, Derek H ^a   Krock, Emerson ^a   Ouellet, Jean A ^a   Stone, Laura S ^a,b   Quinn, Thomas M ^a   Haglund, Lisbet ^a,c  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c MONTREAL GENERAL HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; GROWTH FACTOR; INTERLEUKIN 15; INTERLEUKIN 6; INTERLEUKIN 8; MONOCYTE CHEMOTACTIC PROTEIN 1; MONOCYTE CHEMOTACTIC PROTEIN 3; NERVE GROWTH FACTOR; SILASTIC; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA; CULTURE MEDIUM;

ANNULUS FIBROSUS; ARTICLE; CELL DEATH; CELL ISOLATION; CONTROLLED STUDY; DISCOGENIC PAIN; DISEASE ASSOCIATION; DISEASE COURSE; HUMAN; HUMAN CELL; INFLAMMATION; INTERVERTEBRAL DISK; INTERVERTEBRAL DISK DEGENERATION; NERVE CELL DIFFERENTIATION; NERVE SPROUTING; NEURITE; NUCLEUS PULPOSUS; PC12 CELL; PHEOCHROMOCYTOMA CELL; PROTEIN EXPRESSION; UPREGULATION; ANIMAL; COMPLICATION; CULTURE MEDIUM; MECHANICAL STRESS; METABOLISM; PAIN; PATHOPHYSIOLOGY; PC12 CELL LINE; PHARMACOLOGY; RAT; REAL TIME POLYMERASE CHAIN REACTION; YOUNG ADULT;

ANIMALS; CULTURE MEDIA, CONDITIONED; HUMANS; INFLAMMATION; INTERVERTEBRAL DISC; INTERVERTEBRAL DISC DEGENERATION; PAIN; PC12 CELLS; RATS; REAL-TIME POLYMERASE CHAIN REACTION; STRESS, MECHANICAL; YOUNG ADULT;

EID: 84892715888     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/ar4449     Document Type: Article

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