HIF-1α and HIF-2α degradation is differentially regulated in nucleus pulposus cells of the intervertebral disc

Journal of Bone and Mineral Research

Volumn 27, Issue 2, 2012, Pages 401-412

  Fujita, Nobuyuki ^a,b,c   Chiba, Kazuhiro ^b   Shapiro, Irving M ^a   Risbud, Makarand V ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b KEIO UNIVERSITY   (Japan)

^c International University of Health and Welfare Mita Hospital   (Japan)

Author keywords

CARTILAGE; HIF; HYPOXIA; INTERVERTEBRAL DISC; NUCLEUS PULPOSUS; PROLYL HYDROXYLASE

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; PROLYL HYDROXYLASE 2; PROTEASOME; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CELL HYPOXIA; CONTROLLED STUDY; GAIN OF FUNCTION MUTATION; HUMAN; HUMAN CELL; INTERVERTEBRAL DISK; LOSS OF FUNCTION MUTATION; NONHUMAN; NUCLEUS PULPOSUS; OXYGEN TENSION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; STEADY STATE;

EID: 84856160786     PISSN: 08840431     EISSN: 15234681     Source Type: Journal    
DOI: 10.1002/jbmr.538     Document Type: Article

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