Prolonged upright posture induces degenerative changes in intervertebral discs in rat lumbar spine

Spine

Volumn 33, Issue 19, 2008, Pages 2052-2058

  Liang, Qian Qian ^a   Zhou, Quan ^a,b   Zhang, Min ^a   Hou, Wei ^a   Cui, Xue Jun ^a   Li, Chen Guang ^a   Li, Tian Fang ^a,b   Shi, Qi ^a   Wang, Yong Jun ^a  

^a SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

Animal model; Degeneration; Extracellular matrix; Lumbar

Indexed keywords

AGGRECAN; COLLAGEN TYPE 10; COLLAGEN TYPE 2; COLLAGENASE 3; DISINTEGRIN; MESSENGER RNA; METALLOPROTEINASE; WATER; ADAM PROTEIN; ADAMTS 5 PROTEIN, RAT; ADAMTS-5 PROTEIN, RAT; AGC1 PROTEIN, RAT; BIOLOGICAL MARKER; COL2A1 PROTEIN, RAT;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARTILAGE; CONTROLLED STUDY; DOWN REGULATION; FOOD; FORELIMB; HINDLIMB; HISTOLOGY; IMMUNOHISTOCHEMISTRY; INTERVERTEBRAL DISK; INTERVERTEBRAL DISK DEGENERATION; LIMB AMPUTATION; LUMBAR SPINE; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN STRUCTURE; RAT; REAL TIME POLYMERASE CHAIN REACTION; RNA ISOLATION; STANDING; TAIL; UPREGULATION; ANIMAL; BODY POSTURE; DISEASE MODEL; GENE EXPRESSION; GENETICS; INTERVERTEBRAL DISK HERNIA; MECHANICAL STRESS; METABOLISM; PATHOLOGY; SPRAGUE DAWLEY RAT; WEIGHT BEARING;

ADAM PROTEINS; AGGRECANS; ANIMALS; BIOLOGICAL MARKERS; COLLAGEN TYPE II; COLLAGEN TYPE X; DISEASE MODELS, ANIMAL; FORELIMB; GENE EXPRESSION; INTERVERTEBRAL DISK; INTERVERTEBRAL DISK DISPLACEMENT; MALE; MATRIX METALLOPROTEINASE 13; POSTURE; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; STRESS, MECHANICAL; TAIL; UP-REGULATION; WEIGHT-BEARING;

EID: 55449106580     PISSN: 03622436     EISSN: 15281159     Source Type: Journal    
DOI: 10.1097/BRS.0b013e318183f949     Document Type: Article

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