Enhancement of intervertebral disc cell senescence by WNT/β-catenin signaling-induced matrix metalloproteinase expression

Arthritis and Rheumatism

Volumn 62, Issue 10, 2010, Pages 3036-3047

  Hiyama, Akihiko ^a   Sakai, Daisuke ^a   Risbud, Makarand V ^b   Tanaka, Masahiro ^a   Arai, Fumiyuki ^a   Abe, Koichiro ^a   Mochida, Joji ^a  

^a TOKAI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGGRECAN; BETA CATENIN; BETA GALACTOSIDASE; BONE MORPHOGENETIC PROTEIN; LITHIUM CHLORIDE; MATRIX METALLOPROTEINASE; MESSENGER RNA; TRANSFORMING GROWTH FACTOR BETA; WNT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL AGING; CELL CYCLE ARREST; CELL PROLIFERATION; CONTROLLED STUDY; FEMALE; GENE ACTIVATION; GENETIC TRANSFECTION; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; INTERVERTEBRAL DISK; INTERVERTEBRAL DISK DEGENERATION; MICROARRAY ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; NUCLEUS PULPOSUS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; BETA CATENIN; CELL AGING; CELL CYCLE; CELLS, CULTURED; FEMALE; INTERVERTEBRAL DISK; INTERVERTEBRAL DISK DEGENERATION; LUMBAR VERTEBRAE; MATRIX METALLOPROTEINASES; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; WNT PROTEINS;

EID: 77957688083     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.27599     Document Type: Article

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