Investigating the role of DNA damage in tobacco smoking-induced spine degeneration

Spine Journal

Volumn 14, Issue 3, 2014, Pages 416-423

  Nasto, Luigi A ^a,b   Ngo, Kevin ^a   Leme, Adriana S ^a   Robinson, Andria R ^a   Dong, Qing ^a   Roughley, Peter ^c   Usas, Arvydas ^d   Sowa, Gwendolyn A ^a   Pola, Enrico ^b   Kang, James ^a   Niedernhofer, Laura J ^a,e   Shapiro, Steven ^a   Vo, Nam V ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b CATHOLIC UNIVERSITY   (Italy)

^c SHRINERS HOSPITAL FOR CHILDREN   (Canada)

^d UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^e SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Aggrecan; DNA damage repair; Intervertebral disc degeneration; Matrix metalloproteinases; Matrix proteoglycans; Tobacco smoking

Indexed keywords

AGGRECAN; PROTEOGLYCAN;

ADVERSE EFFECTS; ANIMAL; C57BL MOUSE; DISEASE MODEL; DNA DAMAGE; FEMALE; INTERVERTEBRAL DISC DEGENERATION; INTERVERTEBRAL DISK; MALE; METABOLISM; MICRO-COMPUTED TOMOGRAPHY; MOUSE; PATHOPHYSIOLOGY; PHYSIOLOGY; RADIOGRAPHY; RISK FACTOR; SMOKING;

AGGRECANS; ANIMALS; DISEASE MODELS, ANIMAL; DNA DAMAGE; FEMALE; INTERVERTEBRAL DISC; INTERVERTEBRAL DISC DEGENERATION; MALE; MICE; MICE, INBRED C57BL; PROTEOGLYCANS; RISK FACTORS; SMOKING; X-RAY MICROTOMOGRAPHY;

EID: 84894425812     PISSN: 15299430     EISSN: 18781632     Source Type: Journal    
DOI: 10.1016/j.spinee.2013.08.034     Document Type: Article

References (41)

1. D. Borenstein Epidemiology, etiology, diagnostic evaluation, and treatment of low back pain Curr Opin Rheumatol 4 1992 226 232
2. L.G. Hart, R.A. Deyo, and D.C. Cherkin Physician office visits for low back pain. Frequency, clinical evaluation, and treatment patterns from a U.S. national survey Spine 20 1995 11 19
3. K. Luoma, H. Riihimäki, and R. Luukkonen et al. Low back pain in relation to lumbar disc degeneration Spine 25 2000 487 492
4. K.M. Cheung, D. Samartzis, J. Karppinen, and K.D. Luk Are "patterns" of lumbar disc degeneration associated with low back pain? New insights based on skipped level disc pathology Spine 37 2012 E430 E438
5. E.I. de Schepper, J. Damen, and J.B. van Meurs et al. The association between lumbar disc degeneration and low back pain: the influence of age, gender, and individual radiographic features Spine 35 2010 531 536
6. M.O. Erkintalo, J.J. Salminen, and A.M. Alanen et al. Development of degenerative changes in the lumbar intervertebral disk: results of a prospective MR imaging study in adolescents with and without low-back pain Radiology 196 1995 529 533
7. H. Paajanen, M. Erkintalo, and T. Kuusela et al. Magnetic resonance study of disc degeneration in young low-back pain patients Spine 14 1989 982 985
8. M.W. van Tulder, W.J. Assendelft, B.W. Koes, and L.M. Bouter Spinal radiographic findings and nonspecific low back pain. A systematic review of observational studies Spine 22 1997 427 434
9. T. Videman, M.C. Battié, and K. Gill et al. Magnetic resonance imaging findings and their relationships in the thoracic and lumbar spine. Insights into the etiopathogenesis of spinal degeneration Spine 20 1995 928 935
10. M.C. Battie, T. Videman, and E. Parent Lumbar disc degeneration: epidemiology and genetic influences Spine 29 2004 2679 2690
11. L. Ala-Kokko Genetic risk factors for lumbar disc disease Ann Med 34 2002 42 47
12. T. Videman, S. Sarna, and M.C. Battié et al. The long-term effects of physical loading and exercise lifestyles on back-related symptoms, disability, and spinal pathology among men Spine 20 1995 699 709
13. M.C. Battié, T. Videman, and K. Gill et al. 1991 Volvo Award in clinical sciences. Smoking and lumbar intervertebral disc degeneration: an MRI study of identical twins Spine 16 1991 1015 1021
14. R.A. Deyo, and J.E. Bass Lifestyle and low-back pain. The influence of smoking and obesity Spine 14 1989 501 506
15. Centers for Disease Control and Prevention Cigarette smoking among adults - United States, 2007 MMWR Morb Mortal Wkly Rep 57 2008 1221 1226
16. Centers for Disease Control and Prevention Disparities in secondhand smoke exposure - United States, 1988-1994 and 1999-2004 MMWR Morb Mortal Wkly Rep 57 2008 744 747
17. J.W. Frymoyer, M.H. Pope, and M.C. Costanza et al. Epidemiologic studies of low-back pain Spine 5 1980 419 423
18. E. Viikari-Juntura, R. Martikainen, and R. Luukkonen et al. Longitudinal study on work related and individual risk factors affecting radiating neck pain Occup Environ Med 58 2001 345 352
19. D. Wang, L.A. Nasto, and P. Roughley et al. Spine degeneration in a murine model of chronic human tobacco smokers Osteoarthritis Cartilage 20 2012 896 905
20. H.B. El-Zawawy, C.S. Gill, R.W. Wright, and L.J. Sandell Smoking delays chondrogenesis in a mouse model of closed tibial fracture healing J Orthop Res 24 2006 2150 2158
21. S.W. Ueng, S.S. Lee, and S.S. Lin et al. Hyperbaric oxygen therapy mitigates the adverse effect of cigarette smoking on the bone healing of tibial lengthening: an experimental study on rabbits J Trauma 47 1999 752 759
22. T. Ogawa, H. Matsuzaki, and H. Uei et al. Alteration of gene expression in intervertebral disc degeneration of passive cigarette-smoking rats: separate quantitation in separated nucleus pulposus and annulus fibrosus Pathobiology 72 2005 146 151
23. K.S. Ramos, and B. Moorthy Bioactivation of polycyclic aromatic hydrocarbon carcinogens within the vascular wall: implications for human atherogenesis Drug Metab Rev 37 2005 595 610
24. N. Vo, H.Y. Seo, and A. Robinson et al. Accelerated aging of intervertebral discs in a mouse model of progeria J Orthop Res 28 2010 1600 1607
25. R.D. Hautamaki, D.K. Kobayashi, R.M. Senior, and S.D. Shapiro Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice Science 277 1997 2002 2004
26. A.M. Houghton, P.A. Quintero, and D.L. Perkins et al. Elastin fragments drive disease progression in a murine model of emphysema J Clin Invest 116 2006 753 759
27. S.S. Lindblad, P. Mydel, and I.M. Jonsson et al. Smoking and nicotine exposure delay development of collagen-induced arthritis in mice Arthritis Res Ther 11 2009 R88
28. L.A. Nasto, H.Y. Seo, and A.T. Robinson et al. Issls Prize Winner: inhibition of Nf-kb activity ameliorates age-associated disc degeneration in a mouse model of accelerated aging Spine 37 2012 1819 1825
29. R.W. Farndale, D.J. Buttle, and A.J. Barrett Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylmethylene blue Biochim Biophys Acta 883 1986 173 177
30. D. Wang, N.V. Vo, and G.A. Sowa et al. Bupivacaine decreases cell viability and matrix protein synthesis in an intervertebral disc organ model system Spine J 11 2011 139 146
31. L. Gilbertson, S.H. Ahn, and P.N. Teng et al. The effects of recombinant human bone morphogenetic protein-2, recombinant human bone morphogenetic protein-12, and adenoviral bone morphogenetic protein-12 on matrix synthesis in human annulus fibrosis and nucleus pulposus cells Spine J 8 2008 449 456
32. L. Haglund, J. Ouellet, and P. Roughley Variation in chondroadherin abundance and fragmentation in the human scoliotic disc Spine 34 2009 1513 1518
33. E.R. Lee, L. Lamplugh, and M.A. Davoli et al. Enzymes active in the areas undergoing cartilage resorption during the development of the secondary ossification center in the tibiae of rats ages 0-21 days: I. Two groups of proteinases cleave the core protein of aggrecan Dev Dyn 222 2001 52 70
34. E.R. Lee, L. Lamplugh, and C.P. Leblond et al. Immunolocalization of the cleavage of the aggrecan core protein at the Asn341-Phe342 bond, as an indicator of the location of the metalloproteinases active in the lysis of the rat growth plate Anat Rec 252 1998 117 132
35. M.L. Bouxsein, S.K. Boyd, and B.A. Christiansen et al. Guidelines for assessment of bone microstructure in rodents using micro-computed tomography J Bone Miner Res 25 2010 1468 1486
36. P.J. Roughley, M. Alini, and J. Antoniou The role of proteoglycans in aging, degeneration and repair of the intervertebral disc Biochem Soc Trans 30 2002 869 874
37. A.G. Rodriguez, A.E. Rodriguez-Soto, and A.J. Burghardt et al. Morphology of the human vertebral endplate J Orthop Res 30 2012 280 287
38. L.I. Kauppila Ingrowth of blood vessels in disc degeneration. Angiographic and histological studies of cadaveric spines J Bone Joint Surg Am 77 1995 26 31
39. R. Ali, C.L. Le Maitre, and S.M. Richardson et al. Connective tissue growth factor expression in human intervertebral disc: implications for angiogenesis in intervertebral disc degeneration Biotech Histochem 83 2008 239 245
40. X. Xu, and B. Li Exposure-response relationship between passive smoking and adult pulmonary function Am J Respir Crit Care Med 151 1995 41 46
41. 2012 Surgeon General's Report - Preventing tobacco use among youth and young adults. Centers for Disease Control and Prevention. 2012. (Books and Documents). PMID: 22876391.