Autophagy is activated in compression-induced cell degeneration and is mediated by reactive oxygen species in nucleus pulposus cells exposed to compression

Osteoarthritis and Cartilage

Volumn 21, Issue 12, 2013, Pages 2030-2038

  Ma, K G ^a   Shao, Z W ^a   Yang, S H ^a   Wang, J ^a   Wang, B C ^a   Xiong, L M ^a   Wu, Q ^a   Chen, S F ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Apoptosis; Autophagy; Compression; Intervertebral disc; Nucleus pulposus cells; Reactive oxygen species

Indexed keywords

3 METHYLADENINE; CHLOROQUINE; DANSYLCADAVERINE; LIPOCORTIN 5; PROPIDIUM IODIDE; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; APOPTOSIS; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CELL DEGENERATION; CELL PROLIFERATION; CELL STRUCTURE; CELL VIABILITY; COMPRESSION; CONTROLLED STUDY; FLUORESCENCE IMAGING; IMMUNOFLUORESCENCE; IN VITRO STUDY; INTERVERTEBRAL DISK DEGENERATION; MALE; NONHUMAN; NUCLEUS PULPOSUS; PATHOGENESIS; PRIORITY JOURNAL; RAT; TRANSMISSION ELECTRON MICROSCOPY; WESTERN BLOTTING;

APOPTOSIS; AUTOPHAGY; COMPRESSION; INTERVERTEBRAL DISC; NUCLEUS PULPOSUS CELLS; REACTIVE OXYGEN SPECIES;

ADENINE; ANIMALS; APOPTOSIS; AUTOPHAGY; BLOTTING, WESTERN; CELLS, CULTURED; CHLOROQUINE; IMMUNOHISTOCHEMISTRY; INTERVERTEBRAL DISC; INTERVERTEBRAL DISC DEGENERATION; MICROSCOPY, ELECTRON, TRANSMISSION; RATS; REACTIVE OXYGEN SPECIES; STRESS, MECHANICAL;

EID: 84888857607     PISSN: 10634584     EISSN: 15229653     Source Type: Journal    
DOI: 10.1016/j.joca.2013.10.002     Document Type: Article

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