DBP-induced endoplasmic reticulum stress in male germ cells causes autophagy, which has a cytoprotective role against apoptosis in vitro and in vivo

Toxicology Letters

Volumn 245, Issue , 2016, Pages 86-98

  Zhang, Guowei ^a   Liu, Kaijun ^a   Ling, Xi ^a   Wang, Zhi ^a   Zou, Peng ^a   Wang, Xiaogang ^a   Gao, Jianfang ^a   Yin, Li ^a   Zhang, Xi ^a   Liu, Jinyi ^a   Ao, Lin ^a   Cao, Jia ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Autophagy; Dibutyl phthalate; Endoplasmic reticulum stress; Reproductive toxicity

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; GLUCOSE REGULATED PROTEIN 78; INITIATION FACTOR 2ALPHA; PHTHALIC ACID DIBUTYL ESTER; BIOLOGICAL MARKER; PLASTICIZER; SMALL INTERFERING RNA;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHAGY; CELL DAMAGE; CELL PROTECTION; DOSE RESPONSE; ENDOPLASMIC RETICULUM STRESS; GENE SILENCING; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; REPRODUCTIVE TOXICITY; SPERMATOCYTE; TESTIS ATROPHY; ANIMAL; CALCIUM SIGNALING; CELL CULTURE; CELL SURVIVAL; DRUG EFFECTS; GERM CELL; SPRAGUE DAWLEY RAT;

ANIMALS; APOPTOSIS; AUTOPHAGY; BIOMARKERS; CALCIUM SIGNALING; CELL SURVIVAL; CELLS, CULTURED; DIBUTYL PHTHALATE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOPLASMIC RETICULUM STRESS; GENE SILENCING; GERM CELLS; MALE; MICE; PLASTICIZERS; RATS; RATS, SPRAGUE-DAWLEY; RNA, SMALL INTERFERING; SPERMATOCYTES;

EID: 84957593420     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2016.01.016     Document Type: Article

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