Effects of di(n-butyl) and monobutyl phthalate on steroidogenesis pathways in the murine Leydig tumor cell line MLTC-1

Environmental Toxicology and Pharmacology

Volumn 36, Issue 2, 2013, Pages 332-338

  Chen, Xi ^a   Zhou, Qing Hong ^a   Leng, Ling ^a   Chen, Xu ^b   Sun, Zeng Rong ^a   Tang, Nai Jun ^a  

^a TIANJIN MEDICAL UNIVERSITY   (China)

^b Tianjin Center Gynecology and Obstetrical Hospital   (China)

Author keywords

3 Hydroxysteroid dehydrogenase; Di(n butyl) phthalate; Insulin like hormone 3; Monobutyl phthalate; P450 side chain cleavage enzyme; Testosterone

Indexed keywords

3(OR 17)BETA HYDROXYSTEROID DEHYDROGENASE; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); CYTOCHROME P450; DI (N BUTYL)PHTHALATE; INSULIN LIKE HORMONE 3; MESSENGER RNA; PEPTIDE HORMONE; PHTHALIC ACID; PHTHALIC ACID BUTYL ESTER; STEROID 17ALPHA MONOOXYGENASE; UNCLASSIFIED DRUG;

ARTICLE; CELL VIABILITY; CHEMICAL ANALYSIS; CONCENTRATION (PARAMETERS); GENE EXPRESSION; IN VITRO STUDY; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; REPRODUCTIVE TOXICITY; STEROIDOGENESIS; TESTOSTERONE RELEASE; TESTOSTERONE SYNTHESIS; TRANSCRIPTION REGULATION; TRANSLATION REGULATION;

3Β-HYDROXYSTEROID DEHYDROGENASE; DI(N-BUTYL) PHTHALATE; INSULIN-LIKE HORMONE 3; MONOBUTYL PHTHALATE; P450 SIDE-CHAIN CLEAVAGE ENZYME; TESTOSTERONE;

3-HYDROXYSTEROID DEHYDROGENASES; ANIMALS; CELL LINE, TUMOR; CELL SURVIVAL; CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME; DIBUTYL PHTHALATE; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; INSULIN; LEYDIG CELL TUMOR; MALE; MICE; PHTHALIC ACIDS; PROTEINS; RNA, MESSENGER; TESTICULAR NEOPLASMS; TESTOSTERONE; TIME FACTORS;

MURINAE;

EID: 84878417988     PISSN: 13826689     EISSN: 18727077     Source Type: Journal    
DOI: 10.1016/j.etap.2013.04.013     Document Type: Article

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