N-acetylcysteine protects against cadmium-induced germ cell apoptosis by inhibiting endoplasmic reticulum stress in testes

Asian Journal of Andrology

Volumn 15, Issue 2, 2013, Pages 290-296

  Ji, Yan Li ^a   Wang, Hua ^a   Zhang, Cheng ^a   Zhang, Ying ^a   Zhao, Mei ^a   Chen, Yuan Hua ^a   Xu, De Xiang ^a  

^a ANHUI MEDICAL UNIVERSITY   (China)

Author keywords

antioxidant; apoptosis; cadmium; endoplasmic reticulum stress; N acetylcysteine (NAC); testis; unfolded protein response

Indexed keywords

ACETYLCYSTEINE; CADMIUM CHLORIDE; CCAAT ENHANCER BINDING PROTEIN; CHAPERONE; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INITIATION FACTOR 2ALPHA; PROTEIN KINASE R; STRESS ACTIVATED PROTEIN KINASE; X BOX BINDING PROTEIN 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; DRUG EFFECT; DRUG INHIBITION; ENDOPLASMIC RETICULUM STRESS; GERM CELL; GROWTH INHIBITION; MALE; MEDIATOR; MOUSE; NICK END LABELING; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; TESTIS; UNFOLDED PROTEIN RESPONSE;

ACETYLCYSTEINE; ANIMALS; ANTIOXIDANTS; APOPTOSIS; CADMIUM; ENDOPLASMIC RETICULUM STRESS; GLUTATHIONE; HEAT-SHOCK PROTEINS; HEME OXYGENASE-1; MALE; MEMBRANE PROTEINS; MICE; MODELS, BIOLOGICAL; RNA, MESSENGER; SPERMATOZOA; TESTIS; UNFOLDED PROTEIN RESPONSE;

EID: 84874624276     PISSN: 1008682X     EISSN: 17457262     Source Type: Journal    
DOI: 10.1038/aja.2012.129     Document Type: Article

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