Severe global cerebral ischemia-induced programmed necrosis of hippocampal CA1 neurons in rat is prevented by 3-methyladenine: A widely used inhibitor of autophagy

Journal of Neuropathology and Experimental Neurology

Volumn 70, Issue 4, 2011, Pages 314-322

  Wang, Jin Ye ^a,b   Xia, Qiang ^a   Chu, Ke Tan ^a   Pan, Jie ^a   Sun, Li Na ^a   Zeng, Bin ^a   Zhu, Yu Jin ^a   Wang, Qian ^a   Wang, Kai ^b   Luo, Ben Yan ^a  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b ANHUI MEDICAL UNIVERSITY   (China)

Author keywords

3 Methyladenine; Apoptosis; Autophagy; CA1; Cathepsin B; Global ischemia reperfusion injury; Programmed necrosis

Indexed keywords

3 METHYLADENINE; CASPASE 3; CATHEPSIN B;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHAGY; BRAIN ISCHEMIA; BRAIN NERVE CELL; CELL STRUCTURE; CONTROLLED STUDY; DISEASE SEVERITY; ELECTRON MICROSCOPY; ENZYME ACTIVATION; GLOBAL CEREBRAL ISCHEMIA; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MALE; NERVE CELL NECROSIS; NEUROPROTECTION; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; WESTERN BLOTTING;

ADENINE; ANIMALS; AUTOPHAGY; BLOTTING, WESTERN; BRAIN ISCHEMIA; CA1 REGION, HIPPOCAMPAL; CASPASE 3; CATHEPSIN B; CELL COUNT; CELL DEATH; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; MALE; MICROSCOPY, ELECTRON, TRANSMISSION; NECROSIS; NEURONS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 79953221421     PISSN: 00223069     EISSN: 15546578     Source Type: Journal    
DOI: 10.1097/NEN.0b013e31821352bd     Document Type: Article

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