메뉴 건너뛰기




Volumn 19, Issue 4, 2014, Pages 555-566

Autophagy and apoptosis: Where do they meet?

Author keywords

Apoptosis; Autophagy; Bcl 2; Beclin 1; BH3 only proteins; Crosstalk

Indexed keywords

BECLIN 1; BIM PROTEIN; CALPAIN; CASPASE; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; PROTEIN NOXA; PUMA PROTEIN; X LINKED INHIBITOR OF APOPTOSIS; APOPTOSIS REGULATORY PROTEIN;

EID: 84896390397     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-014-0967-2     Document Type: Article
Times cited : (502)

References (100)
  • 1
    • 34548188741 scopus 로고    scopus 로고
    • Self-eating and self-killing: Crosstalk between autophagy and apoptosis
    • 1:CAS:528:DC%2BD2sXpsVartb8%3D 17717517 10.1038/nrm2239
    • Maiuri MC, Zalckvar E, Kimchi A, Kroemer G (2007) Self-eating and self-killing: crosstalk between autophagy and apoptosis. Nat Rev Mol Cell Biol 8:741-752
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 741-752
    • Maiuri, M.C.1    Zalckvar, E.2    Kimchi, A.3    Kroemer, G.4
  • 2
    • 67549142261 scopus 로고    scopus 로고
    • Life and death partners: Apoptosis, autophagy and the cross-talk between them
    • 1:CAS:528:DC%2BD1MXnsV2qs7o%3D 19325568 10.1038/cdd.2009.33
    • Eisenberg-Lerner A, Bialik S, Simon HU, Kimchi A (2009) Life and death partners: apoptosis, autophagy and the cross-talk between them. Cell Death Differ 16:966-975
    • (2009) Cell Death Differ , vol.16 , pp. 966-975
    • Eisenberg-Lerner, A.1    Bialik, S.2    Simon, H.U.3    Kimchi, A.4
  • 3
    • 4344594807 scopus 로고    scopus 로고
    • Apoptosis, autophagy, and more
    • 1:CAS:528:DC%2BD2cXmvFemu78%3D 15325581 10.1016/j.biocel.2004.04.011
    • Lockshin RA, Zakeri Z (2004) Apoptosis, autophagy, and more. Int J Biochem Cell Biol 36:2405-2419
    • (2004) Int J Biochem Cell Biol , vol.36 , pp. 2405-2419
    • Lockshin, R.A.1    Zakeri, Z.2
  • 4
    • 84871250128 scopus 로고    scopus 로고
    • Sphingolipids: Regulators of crosstalk between apoptosis and autophagy
    • 1:CAS:528:DC%2BC3sXhtF2htbw%3D 3520539 23152582 10.1194/jlr.R031278
    • Young MM, Kester M, Wang HG (2013) Sphingolipids: regulators of crosstalk between apoptosis and autophagy. J Lipid Res 54:5-19
    • (2013) J Lipid Res , vol.54 , pp. 5-19
    • Young, M.M.1    Kester, M.2    Wang, H.G.3
  • 5
    • 84868197448 scopus 로고    scopus 로고
    • Programmed cell death pathways in cancer: A review of apoptosis, autophagy and programmed necrosis
    • 1:CAS:528:DC%2BC38XhsFygur3O 23030059 10.1111/j.1365-2184.2012.00845.x
    • Ouyang L, Shi Z, Zhao S, Wang FT, Zhou TT, Liu B et al (2012) Programmed cell death pathways in cancer: a review of apoptosis, autophagy and programmed necrosis. Cell Prolif 45:487-498
    • (2012) Cell Prolif , vol.45 , pp. 487-498
    • Ouyang, L.1    Shi, Z.2    Zhao, S.3    Wang, F.T.4    Zhou, T.T.5    Liu, B.6
  • 7
    • 78650666886 scopus 로고    scopus 로고
    • Astrocyte elevated gene-1 induces protective autophagy
    • 1:CAS:528:DC%2BC3MXitleh 3009793 21127263 10.1073/pnas.1009479107
    • Bhutia SK, Kegelman TP, Das SK, Azab B, Su ZZ, Lee SG et al (2010) Astrocyte elevated gene-1 induces protective autophagy. Proc Natl Acad Sci USA 107:22243-22248
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 22243-22248
    • Bhutia, S.K.1    Kegelman, T.P.2    Das, S.K.3    Azab, B.4    Su, Z.Z.5    Lee, S.G.6
  • 8
    • 0029900295 scopus 로고    scopus 로고
    • The tumor necrosis factor ligand and receptor families
    • 1:CAS:528:DyaK28XksVOmsb4%3D 8637518 10.1056/NEJM199606273342607
    • Bazzoni F, Beutler B (1996) The tumor necrosis factor ligand and receptor families. N Engl J Med 334:1717-1725
    • (1996) N Engl J Med , vol.334 , pp. 1717-1725
    • Bazzoni, F.1    Beutler, B.2
  • 9
    • 68949178567 scopus 로고    scopus 로고
    • Looking beyond death: A morphogenetic role for the TNF signalling pathway
    • 1:CAS:528:DC%2BD1MXovFegu7Y%3D 19494121 10.1242/jcs.044487
    • Mathew SJ, Haubert D, Krönke M, Leptin M (2009) Looking beyond death: a morphogenetic role for the TNF signalling pathway. J Cell Sci 122:1939-1946
    • (2009) J Cell Sci , vol.122 , pp. 1939-1946
    • Mathew, S.J.1    Haubert, D.2    Krönke, M.3    Leptin, M.4
  • 10
    • 84871426027 scopus 로고    scopus 로고
    • The roles of FADD in extrinsic apoptosis and necroptosis
    • 1:CAS:528:DC%2BC38XhsFyitL3K 23010170 10.5483/BMBRep.2012.45.9.186
    • Lee EW, Seo J, Jeong M, Lee S, Song J (2012) The roles of FADD in extrinsic apoptosis and necroptosis. BMB Rep 45:496-508
    • (2012) BMB Rep , vol.45 , pp. 496-508
    • Lee, E.W.1    Seo, J.2    Jeong, M.3    Lee, S.4    Song, J.5
  • 11
    • 84863272549 scopus 로고    scopus 로고
    • The role of TRADD in death receptor signaling
    • 1:CAS:528:DC%2BC38Xlt1aqt74%3D 3679287 22333735 10.4161/cc.11.5.19300
    • Pobezinskaya YL, Liu Z (2012) The role of TRADD in death receptor signaling. Cell Cycle 11:871-886
    • (2012) Cell Cycle , vol.11 , pp. 871-886
    • Pobezinskaya, Y.L.1    Liu, Z.2
  • 14
    • 84870206960 scopus 로고    scopus 로고
    • Mitochondria: Master regulators of danger signalling
    • 1:CAS:528:DC%2BC38Xhslagsr7L 23175281 10.1038/nrm3479
    • Galluzzi L, Kepp O, Kroemer G (2012) Mitochondria: master regulators of danger signalling. Nat Rev Mol Cell Biol 13:780-788
    • (2012) Nat Rev Mol Cell Biol , vol.13 , pp. 780-788
    • Galluzzi, L.1    Kepp, O.2    Kroemer, G.3
  • 15
    • 48849090371 scopus 로고    scopus 로고
    • Bcl-2 family proteins: The sentinels of the mitochondrial apoptosis pathway
    • 10.1002/iub.51
    • Wong WW, Puthalakath H (2008) Bcl-2 family proteins: the sentinels of the mitochondrial apoptosis pathway. IUBMB Life 60:339-390
    • (2008) IUBMB Life , vol.60 , pp. 339-390
    • Wong, W.W.1    Puthalakath, H.2
  • 16
    • 84875876273 scopus 로고    scopus 로고
    • Apoptosome structure, assembly, and procaspase activation
    • 1:CAS:528:DC%2BC3sXlt1CjtLo%3D 23561633 10.1016/j.str.2013.02.024
    • Yuan S, Akey CW (2013) Apoptosome structure, assembly, and procaspase activation. Structure 21:501-515
    • (2013) Structure , vol.21 , pp. 501-515
    • Yuan, S.1    Akey, C.W.2
  • 17
    • 77956680686 scopus 로고    scopus 로고
    • Survivin and IAP proteins in cell-death mechanisms
    • 1:CAS:528:DC%2BC3cXhtVaqsbnN 3198835 20704571 10.1042/BJ20100814
    • Altieri DC (2010) Survivin and IAP proteins in cell-death mechanisms. Biochem J 430:199-205
    • (2010) Biochem J , vol.430 , pp. 199-205
    • Altieri, D.C.1
  • 18
    • 80054025654 scopus 로고    scopus 로고
    • The role of Atg proteins in autophagosome formation
    • 1:CAS:528:DC%2BC3MXhsFyqtbnF 21801009 10.1146/annurev-cellbio-092910- 154005
    • Mizushima N, Yoshimori T, Ohsumi Y (2011) The role of Atg proteins in autophagosome formation. Annu Rev Cell Dev Biol 27:107-132
    • (2011) Annu Rev Cell Dev Biol , vol.27 , pp. 107-132
    • Mizushima, N.1    Yoshimori, T.2    Ohsumi, Y.3
  • 19
    • 70349919804 scopus 로고    scopus 로고
    • Coordination of membrane events during autophagy by multiple class III PI3-kinase complexes
    • 1:CAS:528:DC%2BD1MXht1Srt7bO 2753151 19797076 10.1083/jcb.200907014
    • Simonsen A, Tooze SA (2009) Coordination of membrane events during autophagy by multiple class III PI3-kinase complexes. J Cell Biol 186:773-782
    • (2009) J Cell Biol , vol.186 , pp. 773-782
    • Simonsen, A.1    Tooze, S.A.2
  • 20
    • 77953543377 scopus 로고    scopus 로고
    • The Beclin1-VPS34 complex - At the crossroads of autophagy and beyond
    • 10.1016/j.tcb.2010.03.002
    • Funderbur SF, Wang QJ, Yue Z (2010) The Beclin1-VPS34 complex - at the crossroads of autophagy and beyond. Trends Cell Biol 20:355-362
    • (2010) Trends Cell Biol , vol.20 , pp. 355-362
    • Funderbur, S.F.1    Wang, Q.J.2    Yue, Z.3
  • 21
    • 51049118332 scopus 로고    scopus 로고
    • The Atg8 and Atg12 ubiquitin-like conjugation systems in macroautophagy
    • 1:CAS:528:DC%2BD1cXhtVGgt7jL 2529362 18704115 10.1038/embor.2008.163
    • Geng J, Klionsky DJ (2008) The Atg8 and Atg12 ubiquitin-like conjugation systems in macroautophagy. EMBO Rep 9:859-864
    • (2008) EMBO Rep , vol.9 , pp. 859-864
    • Geng, J.1    Klionsky, D.J.2
  • 22
    • 0034329418 scopus 로고    scopus 로고
    • LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
    • 1:CAS:528:DC%2BD3cXovFaiurk%3D 305793 11060023 10.1093/emboj/19.21.5720
    • Kabeya Y, Mizushima N, Ueno T, Yamamoto A, Kirisako T, Noda T, Kominami E et al (2000) LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J 19:5720-5728
    • (2000) EMBO J , vol.19 , pp. 5720-5728
    • Kabeya, Y.1    Mizushima, N.2    Ueno, T.3    Yamamoto, A.4    Kirisako, T.5    Noda, T.6    Kominami, E.7
  • 23
    • 67650264633 scopus 로고    scopus 로고
    • Atg32 is a mitochondrial protein that confers selectivity during mitophagy
    • 1:CAS:528:DC%2BD1MXpsV2msbY%3D 2746076 19619495 10.1016/j.devcel.2009.06. 014
    • Kanki T, Wang K, Cao Y, Baba M, Klionsky DJ (2009) Atg32 is a mitochondrial protein that confers selectivity during mitophagy. Dev Cell 17:98-109
    • (2009) Dev Cell , vol.17 , pp. 98-109
    • Kanki, T.1    Wang, K.2    Cao, Y.3    Baba, M.4    Klionsky, D.J.5
  • 24
    • 47149089713 scopus 로고    scopus 로고
    • Dynein-dependent movement of autophagosomes mediates efficient encounters with lysosomes
    • 1:CAS:528:DC%2BD1MXhsVyhs77E 18388399 10.1247/csf.08005
    • Kimura S, Noda T, Yoshimori T (2008) Dynein-dependent movement of autophagosomes mediates efficient encounters with lysosomes. Cell Struct Funct 33:109-122
    • (2008) Cell Struct Funct , vol.33 , pp. 109-122
    • Kimura, S.1    Noda, T.2    Yoshimori, T.3
  • 25
    • 0021679848 scopus 로고
    • Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation
    • 1:CAS:528:DyaL2MXhvVyjug%3D%3D 6093263 10.1126/science.6093263
    • Tsujimoto Y, Finger LR, Yunis J, Nowell PC, Croce CM (1984) Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation. Science 226:1097-1099
    • (1984) Science , vol.226 , pp. 1097-1099
    • Tsujimoto, Y.1    Finger, L.R.2    Yunis, J.3    Nowell, P.C.4    Croce, C.M.5
  • 26
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
    • 1:CAS:528:DyaK3sXms1eqtbs%3D 8358790 10.1016/0092-8674(93)90509-O
    • Oltvai ZN, Milliman CL, Korsmeyer SJ (1993) Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 74:609-619
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3
  • 27
    • 33745957572 scopus 로고    scopus 로고
    • Proapoptotic multidomain Bcl-2/Bax family proteins: Mechanisms, physiological roles, and therapeutic opportunities
    • 1:CAS:528:DC%2BD28XmvFaitb4%3D 16729025 10.1038/sj.cdd.4401975
    • Reed JC (2006) Proapoptotic multidomain Bcl-2/Bax family proteins: mechanisms, physiological roles, and therapeutic opportunities. Cell Death Differ 13:1378-1386
    • (2006) Cell Death Differ , vol.13 , pp. 1378-1386
    • Reed, J.C.1
  • 29
    • 78751655392 scopus 로고    scopus 로고
    • Bcl-2 and Bcl-xL play important roles in the crosstalk between autophagy and apoptosis
    • 1:CAS:528:DC%2BC3MXhvFGmsLg%3D 21182587 10.1111/j.1742-4658.2010.07965.x
    • Zhou F, Yang Y, Xing D (2011) Bcl-2 and Bcl-xL play important roles in the crosstalk between autophagy and apoptosis. FEBS J 278:403-413
    • (2011) FEBS J , vol.278 , pp. 403-413
    • Zhou, F.1    Yang, Y.2    Xing, D.3
  • 30
    • 25144457455 scopus 로고    scopus 로고
    • Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy
    • 1:CAS:528:DC%2BD2MXhtVOrurbP 16179260 10.1016/j.cell.2005.07.002
    • Pattingre S, Tassa A, Qu X, Garuti R, Liang XH, Mizushima N et al (2005) Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy. Cell 122:927-939
    • (2005) Cell , vol.122 , pp. 927-939
    • Pattingre, S.1    Tassa, A.2    Qu, X.3    Garuti, R.4    Liang, X.H.5    Mizushima, N.6
  • 31
    • 34547689505 scopus 로고    scopus 로고
    • Molecular basis of Bcl-xL's target recognition versatility revealed by the structure of Bcl-xL in complex with the BH3 domain of Beclin-1
    • 1:CAS:528:DC%2BD2sXovFeqsr8%3D 17659302 10.1016/j.jmb.2007.06.069
    • Feng W, Huang S, Wu H, Zhang M (2007) Molecular basis of Bcl-xL's target recognition versatility revealed by the structure of Bcl-xL in complex with the BH3 domain of Beclin-1. J Mol Biol 372:223-235
    • (2007) J Mol Biol , vol.372 , pp. 223-235
    • Feng, W.1    Huang, S.2    Wu, H.3    Zhang, M.4
  • 32
    • 34249037565 scopus 로고    scopus 로고
    • Crystal structure of the Bcl-xL-Beclin 1 peptide complex: Beclin 1 is a novel BH3-only protein
    • 1:CAS:528:DC%2BD2sXksVShsLk%3D 17337444 10.1074/jbc.M700492200
    • Oberstein A, Jeffrey PD, Shi Y (2007) Crystal structure of the Bcl-xL-Beclin 1 peptide complex: beclin 1 is a novel BH3-only protein. J Biol Chem 282:13123-13132
    • (2007) J Biol Chem , vol.282 , pp. 13123-13132
    • Oberstein, A.1    Jeffrey, P.D.2    Shi, Y.3
  • 33
    • 84864667633 scopus 로고    scopus 로고
    • Bcl-2:beclin-1 complex: Multiple, mechanisms regulating autophagy/apoptosis toggle switch
    • 1:CAS:528:DC%2BC38Xks1Kjtbw%3D 3304572 22485198
    • Marquez RT, Xu L (2012) Bcl-2:beclin-1 complex: multiple, mechanisms regulating autophagy/apoptosis toggle switch. Am J Cancer Res 2:214-221
    • (2012) Am J Cancer Res , vol.2 , pp. 214-221
    • Marquez, R.T.1    Xu, L.2
  • 34
    • 48249092267 scopus 로고    scopus 로고
    • Bcl-2 family members: Dual regulators of apoptosis and autophagy
    • 1:CAS:528:DC%2BD1cXpsVCktrY%3D 2749577 18497563
    • Levine B, Sinha S, Kroemer G (2008) Bcl-2 family members: dual regulators of apoptosis and autophagy. Autophagy 4:600-606
    • (2008) Autophagy , vol.4 , pp. 600-606
    • Levine, B.1    Sinha, S.2    Kroemer, G.3
  • 35
    • 76349114046 scopus 로고    scopus 로고
    • Antagonism of Beclin 1-dependent autophagy by BCL-2 at the endoplasmic reticulum requires NAF-1
    • 1:CAS:528:DC%2BD1MXhsFWjtL%2FE 2830692 20010695 10.1038/emboj.2009.369
    • Chang NC, Nguyen M, Germain M, Shore GC (2010) Antagonism of Beclin 1-dependent autophagy by BCL-2 at the endoplasmic reticulum requires NAF-1. EMBO J 29:606-618
    • (2010) EMBO J , vol.29 , pp. 606-618
    • Chang, N.C.1    Nguyen, M.2    Germain, M.3    Shore, G.C.4
  • 36
    • 79953796695 scopus 로고    scopus 로고
    • Mitochondrial BCL-2 inhibits AMBRA1-induced autophagy
    • 1:CAS:528:DC%2BC3MXisVOntrk%3D 3094111 21358617 10.1038/emboj.2011.49
    • Strappazzon F, Vietri-Rudan M, Campello S, Nazio F, Florenzano F, Fimia GM et al (2011) Mitochondrial BCL-2 inhibits AMBRA1-induced autophagy. EMBO J 30:1195-1208
    • (2011) EMBO J , vol.30 , pp. 1195-1208
    • Strappazzon, F.1    Vietri-Rudan, M.2    Campello, S.3    Nazio, F.4    Florenzano, F.5    Fimia, G.M.6
  • 37
    • 53549089861 scopus 로고    scopus 로고
    • Dual role of JNK1-mediated phosphorylation of Bcl-2 in autophagy and apoptosis regulation
    • 1:CAS:528:DC%2BD1cXht12rurnM 2677707 18769111
    • Wei Y, Sinha S, Levine B (2008) Dual role of JNK1-mediated phosphorylation of Bcl-2 in autophagy and apoptosis regulation. Autophagy 4:949-951
    • (2008) Autophagy , vol.4 , pp. 949-951
    • Wei, Y.1    Sinha, S.2    Levine, B.3
  • 38
    • 61849102389 scopus 로고    scopus 로고
    • DAP-kinase-mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl-xL and induction of autophagy
    • 1:CAS:528:DC%2BD1MXhtFOqt7k%3D 2658558 19180116 10.1038/embor.2008.246
    • Zalckvar E, Berissi H, Mizrachy L, Idelchuk Y, Koren I, Eisenstein M et al (2009) DAP-kinase-mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl-xL and induction of autophagy. EMBO Rep 10:285-292
    • (2009) EMBO Rep , vol.10 , pp. 285-292
    • Zalckvar, E.1    Berissi, H.2    Mizrachy, L.3    Idelchuk, Y.4    Koren, I.5    Eisenstein, M.6
  • 39
    • 73649124551 scopus 로고    scopus 로고
    • Death associated protein kinase (DAPK) and signal transduction: Blebbing in programmed cell death
    • 1:CAS:528:DC%2BC3cXhs1Gmsw%3D%3D 19878312 10.1111/j.1742-4658.2009.07412. x
    • Bovellan M, Fritzsche M, Stevens C, Charras G (2010) Death associated protein kinase (DAPK) and signal transduction: blebbing in programmed cell death. FEBS J 277:58-65
    • (2010) FEBS J , vol.277 , pp. 58-65
    • Bovellan, M.1    Fritzsche, M.2    Stevens, C.3    Charras, G.4
  • 40
    • 78649242978 scopus 로고    scopus 로고
    • HMGB1: A novel Beclin 1-binding protein active in autophagy
    • 1:CAS:528:DC%2BC3cXhs1WltrbM 20935509 10.4161/auto.6.8.13651
    • Kang R, Livesey KM, Zeh HJ, Loze MT, Tang D (2010) HMGB1: a novel Beclin 1-binding protein active in autophagy. Autophagy 6:1209-1211
    • (2010) Autophagy , vol.6 , pp. 1209-1211
    • Kang, R.1    Livesey, K.M.2    Zeh, H.J.3    Loze, M.T.4    Tang, D.5
  • 41
  • 42
    • 77957106729 scopus 로고    scopus 로고
    • HMGB1 release and redox regulates autophagy and apoptosis in cancer cells
    • 1:CAS:528:DC%2BC3cXos1aitLg%3D 2945431 20622903 10.1038/onc.2010.261
    • Tang D, Kang R, Cheh CW, Livesey KM, Liang X, Schapiro NE et al (2010) HMGB1 release and redox regulates autophagy and apoptosis in cancer cells. Oncogene 29:5299-5310
    • (2010) Oncogene , vol.29 , pp. 5299-5310
    • Tang, D.1    Kang, R.2    Cheh, C.W.3    Livesey, K.M.4    Liang, X.5    Schapiro, N.E.6
  • 43
    • 34248998801 scopus 로고    scopus 로고
    • Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1
    • 1:CAS:528:DC%2BD2sXlt1KksLc%3D 1868901 17446862 10.1038/sj.emboj.7601689
    • Maiuri MC, Le Toumelin G, Criollo A, Rain JC, Gautier F, Juin P et al (2007) Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1. EMBO J 26:2527-2539
    • (2007) EMBO J , vol.26 , pp. 2527-2539
    • Maiuri, M.C.1    Le Toumelin, G.2    Criollo, A.3    Rain, J.C.4    Gautier, F.5    Juin, P.6
  • 44
    • 74249109983 scopus 로고    scopus 로고
    • Apoptosis blocks Beclin 1-dependent autophagosome synthesis: An effect rescued by Bcl-xL
    • 1:CAS:528:DC%2BC3cXjt12iug%3D%3D 2894406 19713971 10.1038/cdd.2009.121
    • Luo S, Rubinsztein DC (2010) Apoptosis blocks Beclin 1-dependent autophagosome synthesis: an effect rescued by Bcl-xL. Cell Death Differ 17:268-277
    • (2010) Cell Death Differ , vol.17 , pp. 268-277
    • Luo, S.1    Rubinsztein, D.C.2
  • 45
    • 67650219052 scopus 로고    scopus 로고
    • Nix directly binds to GABARAP: A possible crosstalk between apoptosis and autophagy
    • 1:CAS:528:DC%2BD1MXpvFCisr4%3D 19363302 10.4161/auto.5.5.8494
    • Schwarten M, Mohrlüder J, Ma P, Stoldt M, Thielmann Y, Stangler T et al (2009) Nix directly binds to GABARAP: a possible crosstalk between apoptosis and autophagy. Autophagy 5:690-698
    • (2009) Autophagy , vol.5 , pp. 690-698
    • Schwarten, M.1    Mohrlüder, J.2    Ma, P.3    Stoldt, M.4    Thielmann, Y.5    Stangler, T.6
  • 46
    • 66349121718 scopus 로고    scopus 로고
    • Hypoxia induced autophagy is mediated through hypoxia inducible factor induction of BNIP3 and BNIP3L via their BH3 domains
    • 1:CAS:528:DC%2BD1MXlvFSqu70%3D 2682037 19273585 10.1128/MCB.00166-09
    • Bellot G, Garcia-Medina R, Gounon P, Chiche J, Roux D, Pouyssegur J et al (2009) Hypoxia induced autophagy is mediated through hypoxia inducible factor induction of BNIP3 and BNIP3L via their BH3 domains. Mol Cell Biol 29:2570-2581
    • (2009) Mol Cell Biol , vol.29 , pp. 2570-2581
    • Bellot, G.1    Garcia-Medina, R.2    Gounon, P.3    Chiche, J.4    Roux, D.5    Pouyssegur, J.6
  • 47
    • 67549101188 scopus 로고    scopus 로고
    • Role of BNIP3 and NIX in cell death, autophagy, and mitophagy
    • 1:CAS:528:DC%2BD1MXnsV2qs7Y%3D 2768230 19229244 10.1038/cdd.2009.16
    • Zhang J, Ney PA (2009) Role of BNIP3 and NIX in cell death, autophagy, and mitophagy. Cell Death Differ 16:939-946
    • (2009) Cell Death Differ , vol.16 , pp. 939-946
    • Zhang, J.1    Ney, P.A.2
  • 48
    • 79953306808 scopus 로고    scopus 로고
    • Oncogenic Ras-induced expression of Noxa and Beclin-1 promotes autophagic cell death and limits clonogenic survival
    • 1:CAS:528:DC%2BC3MXks1Wqtrw%3D 21353614 10.1016/j.molcel.2011.02.009
    • Elgendy M, Sheridan C, Brumatti G, Martin SJ (2011) Oncogenic Ras-induced expression of Noxa and Beclin-1 promotes autophagic cell death and limits clonogenic survival. Mol Cell 42:23-35
    • (2011) Mol Cell , vol.42 , pp. 23-35
    • Elgendy, M.1    Sheridan, C.2    Brumatti, G.3    Martin, S.J.4
  • 49
    • 1542353401 scopus 로고    scopus 로고
    • Control of apoptosis by p53
    • 1:CAS:528:DC%2BD3sXpsFOmsrk%3D 14663481 10.1038/sj.onc.1207116
    • Fridman JS, Lowe SW (2003) Control of apoptosis by p53. Oncogene 22:9030-9040
    • (2003) Oncogene , vol.22 , pp. 9030-9040
    • Fridman, J.S.1    Lowe, S.W.2
  • 50
    • 33745885329 scopus 로고    scopus 로고
    • DRAM, a p53-induced modulator of autophagy, is critical for apoptosis
    • 1:CAS:528:DC%2BD28Xns1Cgt7w%3D 16839881 10.1016/j.cell.2006.05.034
    • Crighton D, Wilkinson S, O'Prey J, Syed N, Smith P, Harrison PR et al (2006) DRAM, a p53-induced modulator of autophagy, is critical for apoptosis. Cell 126:121-134
    • (2006) Cell , vol.126 , pp. 121-134
    • Crighton, D.1    Wilkinson, S.2    O'Prey, J.3    Syed, N.4    Smith, P.5    Harrison, P.R.6
  • 52
    • 67650745428 scopus 로고    scopus 로고
    • PUMA- and Bax-induced autophagy contributes to apoptosis
    • 1:CAS:528:DC%2BD1MXoslOiur8%3D 2711052 19300452 10.1038/cdd.2009.28
    • Yee KS, Wilkinson S, James J, Ryan KM, Vousden KH (2009) PUMA- and Bax-induced autophagy contributes to apoptosis. Cell Death Differ 16:1135-1145
    • (2009) Cell Death Differ , vol.16 , pp. 1135-1145
    • Yee, K.S.1    Wilkinson, S.2    James, J.3    Ryan, K.M.4    Vousden, K.H.5
  • 53
    • 84864942148 scopus 로고    scopus 로고
    • Bim inhibits autophagy by recruiting Beclin 1 to microtubules
    • 1:CAS:528:DC%2BC38Xptlais7o%3D 3419265 22742832 10.1016/j.molcel.2012.05. 040
    • Luo S, Garcia-Arencibia M, Zhao R, Puri C, Toh PP, Sadiq O et al (2012) Bim inhibits autophagy by recruiting Beclin 1 to microtubules. Mol Cell 47:359-370
    • (2012) Mol Cell , vol.47 , pp. 359-370
    • Luo, S.1    Garcia-Arencibia, M.2    Zhao, R.3    Puri, C.4    Toh, P.P.5    Sadiq, O.6
  • 54
    • 84882448234 scopus 로고    scopus 로고
    • XIAP inhibits autophagy via XIAP-Mdm2-p53 signalling
    • 1:CAS:528:DC%2BC3sXptValtbc%3D 23749209 10.1038/emboj.2013.133
    • Huang X, Wu Z, Mei Y, Wu M (2013) XIAP inhibits autophagy via XIAP-Mdm2-p53 signalling. EMBO J 32:2204-2216
    • (2013) EMBO J , vol.32 , pp. 2204-2216
    • Huang, X.1    Wu, Z.2    Mei, Y.3    Wu, M.4
  • 55
    • 78649251041 scopus 로고    scopus 로고
    • The in vitro cleavage of the hAtg proteins by cell death proteases
    • 1:CAS:528:DC%2BC3cXhs1WltrjO 21121091 10.4161/auto.6.8.13337
    • Norman JM, Cohen GM, Bampton ET (2010) The in vitro cleavage of the hAtg proteins by cell death proteases. Autophagy 6:1042-1056
    • (2010) Autophagy , vol.6 , pp. 1042-1056
    • Norman, J.M.1    Cohen, G.M.2    Bampton, E.T.3
  • 56
    • 0036160679 scopus 로고    scopus 로고
    • Mammalian target of rapamycin (mTOR): Pro- and anti-apoptotic
    • 1:CAS:528:DC%2BD38XitFegtr8%3D 11840159 10.1038/sj.cdd.4400978
    • Castedo M, Ferri KF, Kroemer G (2002) Mammalian target of rapamycin (mTOR): pro- and anti-apoptotic. Cell Death Differ 9:99-100
    • (2002) Cell Death Differ , vol.9 , pp. 99-100
    • Castedo, M.1    Ferri, K.F.2    Kroemer, G.3
  • 57
    • 43249124698 scopus 로고    scopus 로고
    • PRAS40 and PRR5-like protein are new mTOR interactors that regulate apoptosis
    • 2075366 18030348 10.1371/journal.pone.0001217
    • Thedieck K, Polak P, Kim ML, Molle KD, Cohen A, Jenö P et al (2007) PRAS40 and PRR5-like protein are new mTOR interactors that regulate apoptosis. PLoS One 2:e1217
    • (2007) PLoS One , vol.2 , pp. 1217
    • Thedieck, K.1    Polak, P.2    Kim, M.L.3    Molle, K.D.4    Cohen, A.5    Jenö, P.6
  • 58
    • 84875252908 scopus 로고    scopus 로고
    • MTOR inhibitor RAD001 (everolimus) induces apoptotic, not autophagic cell death, in human nasopharyngeal carcinoma cells
    • 1:CAS:528:DC%2BC3sXmtV2isL8%3D 23426850
    • Cai Y, Xia Q, Su Q, Luo R, Sun Y, Shi Y et al (2013) mTOR inhibitor RAD001 (everolimus) induces apoptotic, not autophagic cell death, in human nasopharyngeal carcinoma cells. Int J Mol Med 31:904-912
    • (2013) Int J Mol Med , vol.31 , pp. 904-912
    • Cai, Y.1    Xia, Q.2    Su, Q.3    Luo, R.4    Sun, Y.5    Shi, Y.6
  • 59
    • 84879843923 scopus 로고    scopus 로고
    • Inhibition of autophagy enhances apoptosis induced by the PI3 K/AKT/mTor inhibitor NVP-BEZ235 in renal cell carcinoma cells
    • 1:CAS:528:DC%2BC3sXhtVeitbnK 23086777 10.1002/cbf.2917
    • Li H, Jin X, Zhang Z, Xing Y, Kong X (2013) Inhibition of autophagy enhances apoptosis induced by the PI3 K/AKT/mTor inhibitor NVP-BEZ235 in renal cell carcinoma cells. Cell Biochem Funct 31:427-433
    • (2013) Cell Biochem Funct , vol.31 , pp. 427-433
    • Li, H.1    Jin, X.2    Zhang, Z.3    Xing, Y.4    Kong, X.5
  • 60
    • 57749089665 scopus 로고    scopus 로고
    • Caspase-mediated cleavage of ATG6/Beclin-1 links apoptosis to autophagy in HeLa cells
    • 1:CAS:528:DC%2BD1cXhsFCmsLvJ 18842334 10.1016/j.canlet.2008.09.004
    • Cho DH, Jo YK, Hwang JJ, Lee YM, Roh SA, Kim JC (2009) Caspase-mediated cleavage of ATG6/Beclin-1 links apoptosis to autophagy in HeLa cells. Cancer Lett 274:95-100
    • (2009) Cancer Lett , vol.274 , pp. 95-100
    • Cho, D.H.1    Jo, Y.K.2    Hwang, J.J.3    Lee, Y.M.4    Roh, S.A.5    Kim, J.C.6
  • 61
    • 79953230490 scopus 로고    scopus 로고
    • Beclin 1 cleavage by caspase-3 inactivates autophagy and promotes apoptosis
    • 1:CAS:528:DC%2BC3cXosleltb8%3D 21203962 10.1007/s13238-010-0048-4
    • Zhu Y, Zhao L, Liu L, Gao P, Tian W, Wang X et al (2010) Beclin 1 cleavage by caspase-3 inactivates autophagy and promotes apoptosis. Protein Cell 1:468-477
    • (2010) Protein Cell , vol.1 , pp. 468-477
    • Zhu, Y.1    Zhao, L.2    Liu, L.3    Gao, P.4    Tian, W.5    Wang, X.6
  • 62
    • 78649636176 scopus 로고    scopus 로고
    • Caspase-mediated cleavage of Beclin-1 inactivates Beclin-1-induced autophagy and enhances apoptosis by promoting the release of proapoptotic factors from mitochondria
    • 1:STN:280:DC%2BC3M3jtVKmtA%3D%3D 3032505 21364619 10.1038/cddis.2009.16
    • Wirawan E, Vande Walle L, Kersse K, Cornelis S, Claerhout S, Vanoverberghe I et al (2010) Caspase-mediated cleavage of Beclin-1 inactivates Beclin-1-induced autophagy and enhances apoptosis by promoting the release of proapoptotic factors from mitochondria. Cell Death Dis 1:e18
    • (2010) Cell Death Dis , vol.1 , pp. 18
    • Wirawan, E.1    Vande Walle, L.2    Kersse, K.3    Cornelis, S.4    Claerhout, S.5    Vanoverberghe, I.6
  • 63
    • 84865155931 scopus 로고    scopus 로고
    • Proteolysis of Ambra1 during apoptosis has a role in the inhibition of the autophagic pro-survival response
    • 1:CAS:528:DC%2BC38Xht1WltbzJ 3422474 22441670 10.1038/cdd.2012.27
    • Pagliarini V, Wirawan E, Romagnoli A, Ciccosanti F, Lisi G, Lippens S et al (2012) Proteolysis of Ambra1 during apoptosis has a role in the inhibition of the autophagic pro-survival response. Cell Death Differ 19:1495-1504
    • (2012) Cell Death Differ , vol.19 , pp. 1495-1504
    • Pagliarini, V.1    Wirawan, E.2    Romagnoli, A.3    Ciccosanti, F.4    Lisi, G.5    Lippens, S.6
  • 64
    • 84866098743 scopus 로고    scopus 로고
    • Dismantling the autophagic arsenal when it is time to die: Concerted AMBRA1 degradation by caspases and calpains
    • 1:CAS:528:DC%2BC38XhsFChtL7F 22575990 10.4161/auto.20671
    • Corazzari M, Fimia GM, Piacentini M (2012) Dismantling the autophagic arsenal when it is time to die: concerted AMBRA1 degradation by caspases and calpains. Autophagy 8:1255-1257
    • (2012) Autophagy , vol.8 , pp. 1255-1257
    • Corazzari, M.1    Fimia, G.M.2    Piacentini, M.3
  • 65
    • 79960022338 scopus 로고    scopus 로고
    • UV irradiation resistance-associated gene suppresses apoptosis by interference with Bax activation
    • 1:CAS:528:DC%2BC3MXmtlelsrk%3D 3128967 21597469 10.1038/embor.2011.79
    • Yin X, Cao L, Kang R, Yang M, Wang Z, Peng Y et al (2011) UV irradiation resistance-associated gene suppresses apoptosis by interference with Bax activation. EMBO Rep 12:727-734
    • (2011) EMBO Rep , vol.12 , pp. 727-734
    • Yin, X.1    Cao, L.2    Kang, R.3    Yang, M.4    Wang, Z.5    Peng, Y.6
  • 66
    • 33749162486 scopus 로고    scopus 로고
    • Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis
    • 1:CAS:528:DC%2BD28XhtVWqsLfP 16998475 10.1038/ncb1482
    • Yousefi S, Perozzo R, Schmid I, Ziemiecki A, Schaffner T, Scapozza L et al (2006) Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis. Nat Cell Biol 8:1124-1132
    • (2006) Nat Cell Biol , vol.8 , pp. 1124-1132
    • Yousefi, S.1    Perozzo, R.2    Schmid, I.3    Ziemiecki, A.4    Schaffner, T.5    Scapozza, L.6
  • 67
    • 77951761420 scopus 로고    scopus 로고
    • Mechanism of autophagy to apoptosis switch triggered in prostate cancer cells by antitumor cytokine melanoma differentiation-associated gene 7/interleukin-24
    • 1:CAS:528:DC%2BC3cXltlens7g%3D 2874885 20406981 10.1158/0008-5472.CAN-09- 3647
    • Bhutia SK, Dash R, Das SK, Azab B, Su ZZ, Lee SG et al (2010) Mechanism of autophagy to apoptosis switch triggered in prostate cancer cells by antitumor cytokine melanoma differentiation-associated gene 7/interleukin-24. Cancer Res 70:3667-3676
    • (2010) Cancer Res , vol.70 , pp. 3667-3676
    • Bhutia, S.K.1    Dash, R.2    Das, S.K.3    Azab, B.4    Su, Z.Z.5    Lee, S.G.6
  • 68
    • 69649090647 scopus 로고    scopus 로고
    • Caspase cleavage of Atg4D stimulates GABARAP-L1 processing and triggers mitochondrial targeting and apoptosis
    • 1:CAS:528:DC%2BD1MXpvFGlsrs%3D 2704886 19549685 10.1242/jcs.046250
    • Betin VM, Lane JD (2009) Caspase cleavage of Atg4D stimulates GABARAP-L1 processing and triggers mitochondrial targeting and apoptosis. J Cell Sci 122(Pt 14):2554-2566
    • (2009) J Cell Sci , vol.122 , Issue.PART 14 , pp. 2554-2566
    • Betin, V.M.1    Lane, J.D.2
  • 69
    • 84862280415 scopus 로고    scopus 로고
    • A cryptic mitochondrial targeting motif in Atg4D links caspase cleavage with mitochondrial import and oxidative stress
    • 1:CAS:528:DC%2BC38Xht1art73J 3405841 22441018 10.4161/auto.19227
    • Betin VM, MacVicar TD, Parsons SF, Anstee DJ, Lane JD (2012) A cryptic mitochondrial targeting motif in Atg4D links caspase cleavage with mitochondrial import and oxidative stress. Autophagy 8:664-676
    • (2012) Autophagy , vol.8 , pp. 664-676
    • Betin, V.M.1    Macvicar, T.D.2    Parsons, S.F.3    Anstee, D.J.4    Lane, J.D.5
  • 70
    • 83455225635 scopus 로고    scopus 로고
    • The autophagy protein Atg12 associates with antiapoptotic Bcl-2 family members to promote mitochondrial apoptosis
    • 1:CAS:528:DC%2BC3MXhs1Sktb7F 22152474 10.1016/j.molcel.2011.10.014
    • Rubinstein AD, Eisenstein M, Ber Y, Bialik S, Kimchi A (2011) The autophagy protein Atg12 associates with antiapoptotic Bcl-2 family members to promote mitochondrial apoptosis. Mol Cell 44:698-709
    • (2011) Mol Cell , vol.44 , pp. 698-709
    • Rubinstein, A.D.1    Eisenstein, M.2    Ber, Y.3    Bialik, S.4    Kimchi, A.5
  • 71
    • 77955637249 scopus 로고    scopus 로고
    • ATG12 conjugation to ATG3 regulates mitochondrial homeostasis and cell death
    • 10.1016/j.cell.2010.07.018
    • Radoshevich L, Murrow L, Chen N, Fernandez E, Roy S, Fung C et al (2010) ATG12 conjugation to ATG3 regulates mitochondrial homeostasis and cell death. Cell 42:590-600
    • (2010) Cell , vol.42 , pp. 590-600
    • Radoshevich, L.1    Murrow, L.2    Chen, N.3    Fernandez, E.4    Roy, S.5    Fung, C.6
  • 72
    • 55949083821 scopus 로고    scopus 로고
    • FADD and caspase-8 control the outcome of autophagic signaling in proliferating T cells
    • 1:CAS:528:DC%2BD1cXhtleks77N 2575479 18946037 10.1073/pnas.0808597105
    • Bell BD, Leverrier S, Weist BM, Newton RH, Arechiga AF, Luhrs KA et al (2008) FADD and caspase-8 control the outcome of autophagic signaling in proliferating T cells. Proc Natl Acad Sci USA 105:16677-16682
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 16677-16682
    • Bell, B.D.1    Leverrier, S.2    Weist, B.M.3    Newton, R.H.4    Arechiga, A.F.5    Luhrs, K.A.6
  • 73
    • 20144381544 scopus 로고    scopus 로고
    • Essential roles of Atg5 and FADD in autophagic cell death: Dissection of autophagic cell death into vacuole formation and cell death
    • 1:CAS:528:DC%2BD2MXktlClsbw%3D 15778222 10.1074/jbc.M413934200
    • Pyo JO, Jang MH, Kwon YK, Lee HJ, Jun JI, Woo HN et al (2005) Essential roles of Atg5 and FADD in autophagic cell death: dissection of autophagic cell death into vacuole formation and cell death. J Biol Chem 280:20722-20729
    • (2005) J Biol Chem , vol.280 , pp. 20722-20729
    • Pyo, J.O.1    Jang, M.H.2    Kwon, Y.K.3    Lee, H.J.4    Jun, J.I.5    Woo, H.N.6
  • 74
    • 70449529788 scopus 로고    scopus 로고
    • FLIP-mediated autophagy regulation in cell death control
    • 1:CAS:528:DC%2BD1MXhtlCnu73J 2802862 19838173 10.1038/ncb1980
    • Lee JS, Li Q, Lee JY, Lee SH, Jeong JH, Lee HR et al (2009) FLIP-mediated autophagy regulation in cell death control. Nat Cell Biol 11:1355-1362
    • (2009) Nat Cell Biol , vol.11 , pp. 1355-1362
    • Lee, J.S.1    Li, Q.2    Lee, J.Y.3    Lee, S.H.4    Jeong, J.H.5    Lee, H.R.6
  • 75
    • 84865128914 scopus 로고    scopus 로고
    • Cleavage of Atg3 protein by caspase-8 regulates autophagy during receptor-activated cell death
    • 1:CAS:528:DC%2BC38XptFWitbg%3D 22644571 10.1007/s10495-012-0735-0
    • Oral O, Oz-Arslan D, Itah Z, Naghavi A, Deveci R, Karacali S et al (2012) Cleavage of Atg3 protein by caspase-8 regulates autophagy during receptor-activated cell death. Apoptosis 17:810-820
    • (2012) Apoptosis , vol.17 , pp. 810-820
    • Oral, O.1    Oz-Arslan, D.2    Itah, Z.3    Naghavi, A.4    Deveci, R.5    Karacali, S.6
  • 77
    • 65549085701 scopus 로고    scopus 로고
    • Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling
    • 1:CAS:528:DC%2BD1MXosVClt7o%3D 19427028 10.1016/j.cell.2009.03.015
    • Jin Z, Li Y, Pitti R, Lawrence D, Pham VC, Lill JR et al (2009) Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling. Cell 137:721-735
    • (2009) Cell , vol.137 , pp. 721-735
    • Jin, Z.1    Li, Y.2    Pitti, R.3    Lawrence, D.4    Pham, V.C.5    Lill, J.R.6
  • 78
    • 84888363061 scopus 로고    scopus 로고
    • P62/sequestosome-1 upregulation promotes ABT-263-induced caspase-8 aggregation/activation on the autophagosome
    • 1:CAS:528:DC%2BC3sXhvV2ru7bE 24121507 10.1074/jbc.M113.518134
    • Huang S, Okamoto K, Yu C, Sinicrope FA (2013) p62/sequestosome-1 upregulation promotes ABT-263-induced caspase-8 aggregation/activation on the autophagosome. J Biol Chem 288(47):33654-33666
    • (2013) J Biol Chem , vol.288 , Issue.47 , pp. 33654-33666
    • Huang, S.1    Okamoto, K.2    Yu, C.3    Sinicrope, F.A.4
  • 79
    • 84868150657 scopus 로고    scopus 로고
    • Albumin prevents reactive oxygen species-induced mitochondrial damage, autophagy, and apoptosis during serum starvation
    • 1:CAS:528:DC%2BC38XhsVOnsb7E 22983605 10.1007/s10495-012-0758-6
    • Liu SY, Chen CL, Yang TT, Huang WC, Hsieh CY, Shen WJ et al (2012) Albumin prevents reactive oxygen species-induced mitochondrial damage, autophagy, and apoptosis during serum starvation. Apoptosis 17:1156-1169
    • (2012) Apoptosis , vol.17 , pp. 1156-1169
    • Liu, S.Y.1    Chen, C.L.2    Yang, T.T.3    Huang, W.C.4    Hsieh, C.Y.5    Shen, W.J.6
  • 80
    • 77957654940 scopus 로고    scopus 로고
    • Autophagic degradation of active caspase-8: A crosstalk mechanism between autophagy and apoptosis
    • 1:CAS:528:DC%2BC3cXhtl2ksr7F 3039736 20724831 10.4161/auto.6.7.13038
    • Hou W, Han J, Lu C, Goldstein LA, Rabinowich H (2010) Autophagic degradation of active caspase-8: a crosstalk mechanism between autophagy and apoptosis. Autophagy 6:891-900
    • (2010) Autophagy , vol.6 , pp. 891-900
    • Hou, W.1    Han, J.2    Lu, C.3    Goldstein, L.A.4    Rabinowich, H.5
  • 81
    • 84859480341 scopus 로고    scopus 로고
    • Autophagosomal membrane serves as platform for intracellular death-inducing signaling complex (iDISC)-mediated caspase-8 activation and apoptosis
    • 1:CAS:528:DC%2BC38XltVyrsrc%3D 3320995 22362782 10.1074/jbc.M111.309104
    • Young MM, Takahashi Y, Khan O, Park S, Hori T, Yun J et al (2012) Autophagosomal membrane serves as platform for intracellular death-inducing signaling complex (iDISC)-mediated caspase-8 activation and apoptosis. J Biol Chem 287:12455-12468
    • (2012) J Biol Chem , vol.287 , pp. 12455-12468
    • Young, M.M.1    Takahashi, Y.2    Khan, O.3    Park, S.4    Hori, T.5    Yun, J.6
  • 82
    • 84866104515 scopus 로고    scopus 로고
    • Metabolic stress in autophagy and cell death pathways
    • 3428762 22952396 10.1101/cshperspect.a008763
    • Altman BJ, Rathmell JC (2012) Metabolic stress in autophagy and cell death pathways. Cold Spring Harb Perspect Biol 4:a008763
    • (2012) Cold Spring Harb Perspect Biol , vol.4 , pp. 008763
    • Altman, B.J.1    Rathmell, J.C.2
  • 84
    • 84891645827 scopus 로고    scopus 로고
    • In vitro and in vivo antitumor effects of Peanut agglutinin through induction of apoptotic and autophagic cell death
    • Mukhopadhyay S, Panda PK, Behera B, Das CK, Hassan MK, Das DN et al (2013) In vitro and in vivo antitumor effects of Peanut agglutinin through induction of apoptotic and autophagic cell death. Food Chem Toxicol 64C:369-377
    • (2013) Food Chem Toxicol , vol.64 C , pp. 369-377
    • Mukhopadhyay, S.1    Panda, P.K.2    Behera, B.3    Das, C.K.4    Hassan, M.K.5    Das, D.N.6
  • 85
    • 78649725645 scopus 로고    scopus 로고
    • Mda-7/IL-24: A unique member of the IL-10 gene family promoting cancer-targeted toxicity
    • 1:CAS:528:DC%2BC3cXhsFamt73P 3164830 20926331 10.1016/j.cytogfr.2010.08. 004
    • Dash R, Bhutia SK, Azab B, Su ZZ, Quinn BA, Kegelmen TP et al (2010) mda-7/IL-24: a unique member of the IL-10 gene family promoting cancer-targeted toxicity. Cytokine Growth Factor Rev 21:381-391
    • (2010) Cytokine Growth Factor Rev , vol.21 , pp. 381-391
    • Dash, R.1    Bhutia, S.K.2    Azab, B.3    Su, Z.Z.4    Quinn, B.A.5    Kegelmen, T.P.6
  • 86
    • 50349098812 scopus 로고    scopus 로고
    • Involvement of protective autophagy in TRAIL resistance of apoptosis-defective tumor cells
    • 1:CAS:528:DC%2BD1cXotF2ktrc%3D 2443661 18375389 10.1074/jbc.M710169200
    • Han J, Hou W, Goldstein LA, Lu C, Stolz DB, Yin XM, Rabinowich H (2008) Involvement of protective autophagy in TRAIL resistance of apoptosis-defective tumor cells. J Biol Chem 283:19665-19677
    • (2008) J Biol Chem , vol.283 , pp. 19665-19677
    • Han, J.1    Hou, W.2    Goldstein, L.A.3    Lu, C.4    Stolz, D.B.5    Yin, X.M.6    Rabinowich, H.7
  • 87
    • 84883133349 scopus 로고    scopus 로고
    • Relevance of cancer initiating/stem cells in carcinogenesis and therapy resistance in oral cancer
    • 1:CAS:528:DC%2BC3sXhtFCqsb7P 23876628 10.1016/j.oraloncology.2013.06.010
    • Sinha N, Mukhopadhyay S, Das DN, Panda PK, Bhutia SK (2013) Relevance of cancer initiating/stem cells in carcinogenesis and therapy resistance in oral cancer. Oral Oncol 49:854-862
    • (2013) Oral Oncol , vol.49 , pp. 854-862
    • Sinha, N.1    Mukhopadhyay, S.2    Das, D.N.3    Panda, P.K.4    Bhutia, S.K.5
  • 88
    • 82955170653 scopus 로고    scopus 로고
    • Addition of a histone deacetylase inhibitor redirects tamoxifen-treated breast cancer cells into apoptosis, which is opposed by the induction of autophagy
    • 1:CAS:528:DC%2BC3MXht1yktL%2FN 3760725 21298336 10.1007/s10549-011-1364-y
    • Thomas S, Thurn KT, Bicaku E, Marchion DC, Münster PN (2011) Addition of a histone deacetylase inhibitor redirects tamoxifen-treated breast cancer cells into apoptosis, which is opposed by the induction of autophagy. Breast Cancer Res Treat 130:437-447
    • (2011) Breast Cancer Res Treat , vol.130 , pp. 437-447
    • Thomas, S.1    Thurn, K.T.2    Bicaku, E.3    Marchion, D.C.4    Münster, P.N.5
  • 89
    • 69949106925 scopus 로고    scopus 로고
    • The double-edged sword of autophagy modulation in cancer
    • 2737083 19706824 10.1158/1078-0432.CCR-07-5023
    • White E, DiPaola RS (2009) The double-edged sword of autophagy modulation in cancer. Clin Cancer Res 15:5308-5316
    • (2009) Clin Cancer Res , vol.15 , pp. 5308-5316
    • White, E.1    Dipaola, R.S.2
  • 90
    • 34648823750 scopus 로고    scopus 로고
    • Autophagy signaling in cancer and its potential as novel target to improve anticancer therapy
    • 1:CAS:528:DC%2BD2sXhtFWhs7zI 10.1016/j.drup.2007.05.001
    • Moretti L, Yang ES, Kim KW, Lu B (2007) Autophagy signaling in cancer and its potential as novel target to improve anticancer therapy. Drug Resist Updates 10:135-143
    • (2007) Drug Resist Updates , vol.10 , pp. 135-143
    • Moretti, L.1    Yang, E.S.2    Kim, K.W.3    Lu, B.4
  • 91
    • 70349969648 scopus 로고    scopus 로고
    • Apoptosis and autophagy: Targeting autophagy signalling in cancer cells - 'Trick or treats'?
    • 1:CAS:528:DC%2BD1MXhtlWrtLnL 19788415 10.1111/j.1742-4658.2009.07332.x
    • Corcelle EA, Puustinen P, Jäättelä M (2009) Apoptosis and autophagy: targeting autophagy signalling in cancer cells - 'Trick or treats'? FEBS J 276:6084-6096
    • (2009) FEBS J , vol.276 , pp. 6084-6096
    • Corcelle, E.A.1    Puustinen, P.2    Jäättelä, M.3
  • 92
    • 43949093441 scopus 로고    scopus 로고
    • Anti-cancer agent siramesine is a lysosomotropic detergent that induces cytoprotective autophagosome accumulation
    • 1:CAS:528:DC%2BD1cXntFynurk%3D 18305408
    • Ostenfeld MS, Høyer-Hansen M, Bastholm L, Fehrenbacher N, Olsen OD, Groth-Pedersen L et al (2008) Anti-cancer agent siramesine is a lysosomotropic detergent that induces cytoprotective autophagosome accumulation. Autophagy 4:487-499
    • (2008) Autophagy , vol.4 , pp. 487-499
    • Ostenfeld, M.S.1    Høyer-Hansen, M.2    Bastholm, L.3    Fehrenbacher, N.4    Olsen, O.D.5    Groth-Pedersen, L.6
  • 93
    • 33947497050 scopus 로고    scopus 로고
    • Differential effects of endoplasmic reticulum stress-induced autophagy on cell survival
    • 1:CAS:528:DC%2BD2sXhsFKgsLs%3D 17135238 10.1074/jbc.M609267200
    • Ding WX, Ni HM, Gao W, Hou YF, Melan MA, Chen X et al (2007) Differential effects of endoplasmic reticulum stress-induced autophagy on cell survival. J Biol Chem 282:4702-4710
    • (2007) J Biol Chem , vol.282 , pp. 4702-4710
    • Ding, W.X.1    Ni, H.M.2    Gao, W.3    Hou, Y.F.4    Melan, M.A.5    Chen, X.6
  • 94
    • 48249156591 scopus 로고    scopus 로고
    • Autophagy: An emerging target for cancer therapy
    • 18362515
    • Høyer-Hansen M, Jäättelä M (2008) Autophagy: an emerging target for cancer therapy. Autophagy 4:574-580
    • (2008) Autophagy , vol.4 , pp. 574-580
    • Høyer-Hansen, M.1    Jäättelä, M.2
  • 95
    • 84862500391 scopus 로고    scopus 로고
    • Apoptosis, necrosis and autophagy are influenced by metabolic energy sources in cultured rat spermatocytes
    • 22484449 10.1007/s10495-012-0709-2
    • Bustamante-Marín X, Quiroga C, Lavandero S, Reyes JG, Moreno RD (2012) Apoptosis, necrosis and autophagy are influenced by metabolic energy sources in cultured rat spermatocytes. Apoptosis 17:539-550
    • (2012) Apoptosis , vol.17 , pp. 539-550
    • Bustamante-Marín, X.1    Quiroga, C.2    Lavandero, S.3    Reyes, J.G.4    Moreno, R.D.5
  • 96
    • 50949097371 scopus 로고    scopus 로고
    • Crosstalk between autophagy and apoptosis in heart disease
    • 1:CAS:528:DC%2BD1cXptlKnurs%3D 18703786 10.1161/CIRCRESAHA.108.175448
    • Nishida K, Yamaguchi O, Otsu K (2008) Crosstalk between autophagy and apoptosis in heart disease. Circ Res 103:343-351
    • (2008) Circ Res , vol.103 , pp. 343-351
    • Nishida, K.1    Yamaguchi, O.2    Otsu, K.3
  • 97
    • 61849140067 scopus 로고    scopus 로고
    • When apoptosis meets autophagy: Deciding cell fate after trauma and sepsis
    • 1:CAS:528:DC%2BD1MXjt1ahu7o%3D 2814429 19231289 10.1016/j.molmed.2009.01. 002
    • Hsieh YC, Athar M, Chaudry IH (2009) When apoptosis meets autophagy: deciding cell fate after trauma and sepsis. Trends Mol Med 15:129-138
    • (2009) Trends Mol Med , vol.15 , pp. 129-138
    • Hsieh, Y.C.1    Athar, M.2    Chaudry, I.H.3
  • 98
    • 79955964504 scopus 로고    scopus 로고
    • Depletion of Beclin-1 due to proteolytic cleavage by caspases in the Alzheimer's disease brain
    • 1:CAS:528:DC%2BC3MXmtFCktbk%3D 3066274 21081164 10.1016/j.nbd.2010.11.003
    • Rohn TT, Wirawan E, Brown RJ, Harris JR, Masliah E, Vandenabeele P (2011) Depletion of Beclin-1 due to proteolytic cleavage by caspases in the Alzheimer's disease brain. Neurobiol Dis 43:68-78
    • (2011) Neurobiol Dis , vol.43 , pp. 68-78
    • Rohn, T.T.1    Wirawan, E.2    Brown, R.J.3    Harris, J.R.4    Masliah, E.5    Vandenabeele, P.6
  • 99
    • 33746691954 scopus 로고    scopus 로고
    • Autophagy is involved in T cell death after binding of HIV envelope proteins to CXCR4
    • 1:CAS:528:DC%2BD28XnvF2mt74%3D 1523410 16886061 10.1172/JCI26185
    • Espert L, Denizot M, Grimaldi M, Robert-Hebmann V, Gay B, Varbanov M et al (2006) Autophagy is involved in T cell death after binding of HIV envelope proteins to CXCR4. J Clin Invest 116:2161-2172
    • (2006) J Clin Invest , vol.116 , pp. 2161-2172
    • Espert, L.1    Denizot, M.2    Grimaldi, M.3    Robert-Hebmann, V.4    Gay, B.5    Varbanov, M.6
  • 100
    • 0032870475 scopus 로고    scopus 로고
    • Autophagy is activated by apoptotic signalling in sympathetic neurons: An alternative mechanism of death execution
    • 1:CAS:528:DyaK1MXmtFOltLg%3D 10576889 10.1006/mcne.1999.0780
    • Xue L, Fletcher G, Tolkovsky A (1999) Autophagy is activated by apoptotic signalling in sympathetic neurons: an alternative mechanism of death execution. Mol Cell Neurosci 14:180-198
    • (1999) Mol Cell Neurosci , vol.14 , pp. 180-198
    • Xue, L.1    Fletcher, G.2    Tolkovsky, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.