-
4
-
-
20944450486
-
Insulin resistance in non-diabetic patients with non-Alcoholic fatty liver disease: Sites and mechanisms
-
Bugianesi E, Gastaldelli A, Vanni E., et al. Insulin resistance in non-diabetic patients with non-Alcoholic fatty liver disease: sites and mechanisms. Diabetologia. 2005; 48: 634-642
-
(2005)
Diabetologia
, vol.48
, pp. 634-642
-
-
Bugianesi, E.1
Gastaldelli, A.2
Vanni, E.3
-
6
-
-
10644220306
-
Prevalence of hepatic steatosis in an urban population in the United States: Impact of ethnicity
-
Browning JD, Szczepaniak LS, Dobbins R., et al. Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity. Hepatology. 2004; 40: 1387-1395
-
(2004)
Hepatology
, vol.40
, pp. 1387-1395
-
-
Browning, J.D.1
Szczepaniak, L.S.2
Dobbins, R.3
-
7
-
-
0037221394
-
Determinants of the association of overweight with elevated serum alanine aminotransferase activity in the United States
-
Ruhl CE, Everhart JE. Determinants of the association of overweight with elevated serum alanine aminotransferase activity in the United States. Gastroenterology. 2003; 124: 71-79
-
(2003)
Gastroenterology
, vol.124
, pp. 71-79
-
-
Ruhl, C.E.1
Everhart, J.E.2
-
8
-
-
0037129380
-
Nonalcoholic fatty liver disease
-
Angulo P. Nonalcoholic fatty liver disease. N Engl J Med. 2002; 346: 1221-1231
-
(2002)
N Engl J Med
, vol.346
, pp. 1221-1231
-
-
Angulo, P.1
-
9
-
-
84951103456
-
Contribution of beta-cell dysfunction and insulin resistance to cirrhosis-Associated diabetes: Role of severity of liver disease
-
Grancini V, Trombetta M, Lunati ME., et al. Contribution of beta-cell dysfunction and insulin resistance to cirrhosis-Associated diabetes: role of severity of liver disease. J Hepatol. 2015; 63(6):1484-1490
-
(2015)
J Hepatol
, vol.63
, Issue.6
, pp. 1484-1490
-
-
Grancini, V.1
Trombetta, M.2
Lunati, M.E.3
-
10
-
-
0025002079
-
Liver pathology in morbidly obese patients with and without diabetes
-
Silverman JF, OBrien KF, Long S., et al. Liver pathology in morbidly obese patients with and without diabetes. Am J Gastroenterol. 1990; 85: 1349-1355
-
(1990)
Am J Gastroenterol
, vol.85
, pp. 1349-1355
-
-
Silverman, J.F.1
O'Brien, K.F.2
Long, S.3
-
11
-
-
0038142845
-
Nonalcoholic fatty liver disease: An underrecognized cause of cryptogenic cirrhosis
-
Clark JM, Diehl AM. Nonalcoholic fatty liver disease: an underrecognized cause of cryptogenic cirrhosis. Jama. 2003; 289: 3000-3004
-
(2003)
Jama
, vol.289
, pp. 3000-3004
-
-
Clark, J.M.1
Diehl, A.M.2
-
12
-
-
77957375969
-
Risk of cardiovascular disease in patients with nonalcoholic fatty liver disease
-
Targher G, Day CP, Bonora E. Risk of cardiovascular disease in patients with nonalcoholic fatty liver disease. N Engl J Med. 2010; 363: 1341-1350
-
(2010)
N Engl J Med
, vol.363
, pp. 1341-1350
-
-
Targher, G.1
Day, C.P.2
Bonora, E.3
-
13
-
-
0035195908
-
Postprandial triglyceride-rich lipoprotein metabolism and insulin sensitivity in nonalcoholic steatohepatitis patients
-
Cassader M, Gambino R, Musso G., et al. Postprandial triglyceride-rich lipoprotein metabolism and insulin sensitivity in nonalcoholic steatohepatitis patients. Lipids. 2001; 36: 1117-1124
-
(2001)
Lipids
, vol.36
, pp. 1117-1124
-
-
Cassader, M.1
Gambino, R.2
Musso, G.3
-
14
-
-
84927796763
-
Evidence of NAFLD progression from steatosis to fibrosing-steatohepatitis using paired biopsies: Implications for prognosis and clinical management
-
McPherson S, Hardy T, Henderson E., et al. Evidence of NAFLD progression from steatosis to fibrosing-steatohepatitis using paired biopsies: implications for prognosis and clinical management. J Hepatol. 2015; 62: 1148-1155
-
(2015)
J Hepatol
, vol.62
, pp. 1148-1155
-
-
McPherson, S.1
Hardy, T.2
Henderson, E.3
-
15
-
-
84924938800
-
Fibrosis progression in nonalcoholic fatty liver vs nonalcoholic steatohepatitis: A systematic review and meta-Analysis of paired-biopsy studies
-
e1-9; quiz e39-40
-
Singh S, Allen AM, Wang Z., et al. Fibrosis progression in nonalcoholic fatty liver vs nonalcoholic steatohepatitis: a systematic review and meta-Analysis of paired-biopsy studies. Clin Gastroenterol Hepatol. 2015; 13: 643-54.e1-9; quiz e39-40
-
(2015)
Clin Gastroenterol Hepatol
, vol.13
, pp. 643-654
-
-
Singh, S.1
Allen, A.M.2
Wang, Z.3
-
16
-
-
0035856949
-
Insulin signalling and the regulation of glucose and lipid metabolism
-
Saltiel AR, Kahn CR. Insulin signalling and the regulation of glucose and lipid metabolism. Nature. 2001; 414: 799-806
-
(2001)
Nature
, vol.414
, pp. 799-806
-
-
Saltiel, A.R.1
Kahn, C.R.2
-
17
-
-
33645449883
-
The hyperbolic equilibrium between insulin sensitivity and secretion
-
Pacini G. The hyperbolic equilibrium between insulin sensitivity and secretion. Nutr Metab Cardiovasc Dis. 2006; 16 (Suppl 1): S22-7
-
(2006)
Nutr Metab Cardiovasc Dis
, vol.16
, pp. S22-S27
-
-
Pacini, G.1
-
19
-
-
33748312093
-
Dual role of transcription factor FoxO1 in controlling hepatic insulin sensitivity and lipid metabolism
-
Matsumoto M, Han S, Kitamura T., et al. Dual role of transcription factor FoxO1 in controlling hepatic insulin sensitivity and lipid metabolism. J Clin Invest. 2006; 116: 2464-2472
-
(2006)
J Clin Invest
, vol.116
, pp. 2464-2472
-
-
Matsumoto, M.1
Han, S.2
Kitamura, T.3
-
20
-
-
0036251153
-
SREBPs: Activators of the complete program of cholesterol and fatty acid synthesis in the liver
-
Horton JD, Goldstein JL, Brown MS. SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. J Clin Invest. 2002; 109: 1125-1131
-
(2002)
J Clin Invest
, vol.109
, pp. 1125-1131
-
-
Horton, J.D.1
Goldstein, J.L.2
Brown, M.S.3
-
21
-
-
45749114635
-
Increased expression and activity of the transcription factor FOXO1 in nonalcoholic steatohepatitis
-
Valenti L, Rametta R, Dongiovanni P., et al. Increased expression and activity of the transcription factor FOXO1 in nonalcoholic steatohepatitis. Diabetes. 2008; 57: 1355-1362
-
(2008)
Diabetes
, vol.57
, pp. 1355-1362
-
-
Valenti, L.1
Rametta, R.2
Dongiovanni, P.3
-
22
-
-
34548349302
-
Impaired regulation of hepatic glucose production in mice lacking the forkhead transcription factor foxo1 in liver
-
Matsumoto M, Pocai A, Rossetti L., et al. Impaired regulation of hepatic glucose production in mice lacking the forkhead transcription factor foxo1 in liver. Cell Metab. 2007; 6: 208-216
-
(2007)
Cell Metab
, vol.6
, pp. 208-216
-
-
Matsumoto, M.1
Pocai, A.2
Rossetti, L.3
-
23
-
-
20144365700
-
Nuclear trapping of the forkhead transcription factor FoxO1 via Sirt-dependent deacetylation promotes expression of glucogenetic genes
-
Frescas D, Valenti L, Accili D. Nuclear trapping of the forkhead transcription factor FoxO1 via Sirt-dependent deacetylation promotes expression of glucogenetic genes. J Biol Chem. 2005; 280: 20589-20595
-
(2005)
J Biol Chem
, vol.280
, pp. 20589-20595
-
-
Frescas, D.1
Valenti, L.2
Accili, D.3
-
24
-
-
80455135061
-
Dissociation of the glucose and lipid regulatory functions of FoxO1 by targeted knockin of acetylation-defective alleles in mice
-
Banks AS, Kim-Muller JY, Mastracci TL., et al. Dissociation of the glucose and lipid regulatory functions of FoxO1 by targeted knockin of acetylation-defective alleles in mice. Cell Metab. 2011; 14: 587-597
-
(2011)
Cell Metab
, vol.14
, pp. 587-597
-
-
Banks, A.S.1
Kim-Muller, J.Y.2
Mastracci, T.L.3
-
25
-
-
84921859850
-
Modulation of SIRT1-Foxo1 signaling axis by resveratrol: Implications in skeletal muscle aging and insulin resistance
-
Sin TK, Yung BY, Siu PM. Modulation of SIRT1-Foxo1 signaling axis by resveratrol: implications in skeletal muscle aging and insulin resistance. Cell Physiol Biochem. 2015; 35: 541-552
-
(2015)
Cell Physiol Biochem
, vol.35
, pp. 541-552
-
-
Sin, T.K.1
Yung, B.Y.2
Siu, P.M.3
-
26
-
-
84894327806
-
Increased de novo lipogenesis is a distinct characteristic of individuals with nonalcoholic fatty liver disease
-
Lambert JE, Ramos-Roman MA, Browning JD., et al. Increased de novo lipogenesis is a distinct characteristic of individuals with nonalcoholic fatty liver disease. Gastroenterology. 2014; 146: 726-735
-
(2014)
Gastroenterology
, vol.146
, pp. 726-735
-
-
Lambert, J.E.1
Ramos-Roman, M.A.2
Browning, J.D.3
-
27
-
-
14644426519
-
Complementary roles of IRS-1 and IRS-2 in the hepatic regulation of metabolism
-
Taniguchi CM, Ueki K, Kahn R. Complementary roles of IRS-1 and IRS-2 in the hepatic regulation of metabolism. J Clin Invest. 2005; 115: 718-727
-
(2005)
J Clin Invest
, vol.115
, pp. 718-727
-
-
Taniguchi, C.M.1
Ueki, K.2
Kahn, R.3
-
28
-
-
70350417158
-
Akt2 is required for hepatic lipid accumulation in models of insulin resistance
-
Leavens KF, Easton RM, Shulman GI., et al. Akt2 is required for hepatic lipid accumulation in models of insulin resistance. Cell Metab. 2009; 10: 405-418
-
(2009)
Cell Metab
, vol.10
, pp. 405-418
-
-
Leavens, K.F.1
Easton, R.M.2
Shulman, G.I.3
-
29
-
-
2342483040
-
SREBPs suppress IRS-2-mediated insulin signalling in the liver
-
Ide T, Shimano H, Yahagi N., et al. SREBPs suppress IRS-2-mediated insulin signalling in the liver. Nat Cell Biol. 2004; 6: 351-357
-
(2004)
Nat Cell Biol
, vol.6
, pp. 351-357
-
-
Ide, T.1
Shimano, H.2
Yahagi, N.3
-
30
-
-
84880255942
-
Increased insulin receptor substrate 2 expression is associated with steatohepatitis and altered lipid metabolism in obese subjects
-
Rametta R, Mozzi E, Dongiovanni P., et al. Increased insulin receptor substrate 2 expression is associated with steatohepatitis and altered lipid metabolism in obese subjects. Int J Obes (Lond). 2013; 37: 986-992
-
(2013)
Int J Obes (Lond)
, vol.37
, pp. 986-992
-
-
Rametta, R.1
Mozzi, E.2
Dongiovanni, P.3
-
31
-
-
33747047885
-
Targeting foxo1 in mice using antisense oligonucleotide improves hepatic and peripheral insulin action
-
Samuel VT, Choi CS, Phillips TG., et al. Targeting foxo1 in mice using antisense oligonucleotide improves hepatic and peripheral insulin action. Diabetes. 2006; 55: 2042-2050
-
(2006)
Diabetes
, vol.55
, pp. 2042-2050
-
-
Samuel, V.T.1
Choi, C.S.2
Phillips, T.G.3
-
32
-
-
77952575909
-
PTEN in non-Alcoholic fatty liver disease/non-Alcoholic steatohepatitis and cancer
-
Peyrou M, Bourgoin L, Foti M. PTEN in non-Alcoholic fatty liver disease/non-Alcoholic steatohepatitis and cancer. Dig Dis. 2010; 28: 236-246
-
(2010)
Dig Dis
, vol.28
, pp. 236-246
-
-
Peyrou, M.1
Bourgoin, L.2
Foti, M.3
-
33
-
-
84882245596
-
Inhibition of Notch uncouples Akt activation from hepatic lipid accumulation by decreasing mTorc1 stability
-
Pajvani UB, Qiang L, Kangsamaksin T., et al. Inhibition of Notch uncouples Akt activation from hepatic lipid accumulation by decreasing mTorc1 stability. Nat Med. 2013; 19: 1054-1060
-
(2013)
Nat Med
, vol.19
, pp. 1054-1060
-
-
Pajvani, U.B.1
Qiang, L.2
Kangsamaksin, T.3
-
34
-
-
79961173038
-
Inhibition of Notch signaling ameliorates insulin resistance in a FoxO1-dependent manner
-
Pajvani UB, Shawber CJ, Samuel VT., et al. Inhibition of Notch signaling ameliorates insulin resistance in a FoxO1-dependent manner. Nat Med. 2011; 17: 961-967
-
(2011)
Nat Med
, vol.17
, pp. 961-967
-
-
Pajvani, U.B.1
Shawber, C.J.2
Samuel, V.T.3
-
35
-
-
84891762279
-
Hepatic notch signaling correlates with insulin resistance and nonalcoholic fatty liver disease
-
Valenti L, Mendoza RM, Rametta R., et al. Hepatic notch signaling correlates with insulin resistance and nonalcoholic fatty liver disease. Diabetes. 2013; 62: 4052-4062
-
(2013)
Diabetes
, vol.62
, pp. 4052-4062
-
-
Valenti, L.1
Mendoza, R.M.2
Rametta, R.3
-
36
-
-
84867702988
-
Roles of hepatic progenitor cells activation, ductular reaction proliferation and Notch signaling in morbid obesity
-
Liew PL, Wang W, Lee YC., et al. Roles of hepatic progenitor cells activation, ductular reaction proliferation and Notch signaling in morbid obesity. Hepatogastroenterology. 2012; 59: 1921-1927
-
(2012)
Hepatogastroenterology
, vol.59
, pp. 1921-1927
-
-
Liew, P.L.1
Wang, W.2
Lee, Y.C.3
-
37
-
-
84945465558
-
Altered bile acid metabolome in patients with nonalcoholic steatohepatitis
-
Ferslew BC, Xie G, Johnston CK., et al. Altered bile acid metabolome in patients with nonalcoholic steatohepatitis. Dig Dis Sci. 2015;60(11):3318-3328
-
(2015)
Dig Dis Sci
, vol.60
, Issue.11
, pp. 3318-3328
-
-
Ferslew, B.C.1
Xie, G.2
Johnston, C.K.3
-
38
-
-
84909990520
-
Bile acids, obesity, and the metabolic syndrome
-
Ma H, Patti ME. Bile acids, obesity, and the metabolic syndrome. Best Pract Res Clin Gastroenterol. 2014; 28: 573-583
-
(2014)
Best Pract Res Clin Gastroenterol
, vol.28
, pp. 573-583
-
-
Ma, H.1
Patti, M.E.2
-
39
-
-
84891760775
-
Human insulin resistance is associated with increased plasma levels of 12alpha-hydroxylated bile acids
-
Haeusler RA, Astiarraga B, Camastra S., et al. Human insulin resistance is associated with increased plasma levels of 12alpha-hydroxylated bile acids. Diabetes. 2013; 62: 4184-4191
-
(2013)
Diabetes
, vol.62
, pp. 4184-4191
-
-
Haeusler, R.A.1
Astiarraga, B.2
Camastra, S.3
-
40
-
-
84855427221
-
Impaired generation of 12-hydroxylated bile acids links hepatic insulin signaling with dyslipidemia
-
Haeusler RA, Pratt-Hyatt M, Welch CL., et al. Impaired generation of 12-hydroxylated bile acids links hepatic insulin signaling with dyslipidemia. Cell Metab. 2012; 15: 65-74
-
(2012)
Cell Metab
, vol.15
, pp. 65-74
-
-
Haeusler, R.A.1
Pratt-Hyatt, M.2
Welch, C.L.3
-
41
-
-
84921487729
-
Transmembrane 6 superfamily member 2 gene variant disentangles nonalcoholic steatohepatitis from cardiovascular disease
-
Dongiovanni P, Petta S, Maglio C., et al. Transmembrane 6 superfamily member 2 gene variant disentangles nonalcoholic steatohepatitis from cardiovascular disease. Hepatology. 2015; 61: 506-514
-
(2015)
Hepatology
, vol.61
, pp. 506-514
-
-
Dongiovanni, P.1
Petta, S.2
Maglio, C.3
-
42
-
-
51349083814
-
Risk of severe liver disease in nonalcoholic fatty liver disease with normal aminotransferase levels: A role for insulin resistance and diabetes
-
Fracanzani AL, Valenti L, Bugianesi E., et al. Risk of severe liver disease in nonalcoholic fatty liver disease with normal aminotransferase levels: a role for insulin resistance and diabetes. Hepatology. 2008; 48: 792-798
-
(2008)
Hepatology
, vol.48
, pp. 792-798
-
-
Fracanzani, A.L.1
Valenti, L.2
Bugianesi, E.3
-
43
-
-
84928209634
-
Fibrosis stage is the strongest predictor for disease-specific mortality in NAFLD after up to 33 years of follow-up
-
Ekstedt M, Hagstrom H, Nasr P., et al. Fibrosis stage is the strongest predictor for disease-specific mortality in NAFLD after up to 33 years of follow-up. Hepatology. 2015; 61: 1547-1554
-
(2015)
Hepatology
, vol.61
, pp. 1547-1554
-
-
Ekstedt, M.1
Hagstrom, H.2
Nasr, P.3
-
44
-
-
84938057875
-
Liver fibrosis, but no other histologic features, is associated with long-Term outcomes of patients with nonalcoholic fatty liver disease
-
e10
-
Angulo P, Kleiner DE, Dam-Larsen S., et al. Liver fibrosis, but no other histologic features, is associated with long-Term outcomes of patients with nonalcoholic fatty liver disease. Gastroenterology. 2015; 149: 389-97 e10
-
(2015)
Gastroenterology
, vol.149
, pp. 389-397
-
-
Angulo, P.1
Kleiner, D.E.2
Dam-Larsen, S.3
-
45
-
-
0036207720
-
Apolipoprotein synthesis in nonalcoholic steatohepatitis
-
Charlton M, Sreekumar R, Rasmussen D., et al. Apolipoprotein synthesis in nonalcoholic steatohepatitis. Hepatology. 2002; 35: 898-904
-
(2002)
Hepatology
, vol.35
, pp. 898-904
-
-
Charlton, M.1
Sreekumar, R.2
Rasmussen, D.3
-
46
-
-
34250356015
-
Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis
-
Yamaguchi K, Yang L, McCall S., et al. Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis. Hepatology. 2007; 45: 1366-1374
-
(2007)
Hepatology
, vol.45
, pp. 1366-1374
-
-
Yamaguchi, K.1
Yang, L.2
McCall, S.3
-
47
-
-
38649111018
-
Alterations in adipose tissue and hepatic lipid kinetics in obese men and women with nonalcoholic fatty liver disease
-
Fabbrini E, Mohammed BS, Magkos F., et al. Alterations in adipose tissue and hepatic lipid kinetics in obese men and women with nonalcoholic fatty liver disease. Gastroenterology. 2008; 134: 424-431
-
(2008)
Gastroenterology
, vol.134
, pp. 424-431
-
-
Fabbrini, E.1
Mohammed, B.S.2
Magkos, F.3
-
48
-
-
0036300538
-
Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IkappaB-Alpha
-
Itani SI, Ruderman NB, Schmieder F., et al. Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IkappaB-Alpha. Diabetes. 2002; 51: 2005-2011
-
(2002)
Diabetes
, vol.51
, pp. 2005-2011
-
-
Itani, S.I.1
Ruderman, N.B.2
Schmieder, F.3
-
49
-
-
77956022194
-
Inhibition of de novo ceramide synthesis reverses diet-induced insulin resistance and enhances whole-body oxygen consumption
-
Ussher JR, Koves TR, Cadete VJ., et al. Inhibition of de novo ceramide synthesis reverses diet-induced insulin resistance and enhances whole-body oxygen consumption. Diabetes. 2010; 59: 2453-2464
-
(2010)
Diabetes
, vol.59
, pp. 2453-2464
-
-
Ussher, J.R.1
Koves, T.R.2
Cadete, V.J.3
-
50
-
-
5644231992
-
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
-
Ozcan U, Cao Q, Yilmaz E., et al. Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science. 2004; 306: 457-461
-
(2004)
Science
, vol.306
, pp. 457-461
-
-
Ozcan, U.1
Cao, Q.2
Yilmaz, E.3
-
51
-
-
0142091454
-
Ceramide disables 3-phosphoinositide binding to the pleckstrin homology domain of protein kinase B (PKB)/Akt by a PKCzeta-dependent mechanism
-
Powell DJ, Hajduch E, Kular G., et al. Ceramide disables 3-phosphoinositide binding to the pleckstrin homology domain of protein kinase B (PKB)/Akt by a PKCzeta-dependent mechanism. Mol Cell Biol. 2003; 23: 7794-7808
-
(2003)
Mol Cell Biol
, vol.23
, pp. 7794-7808
-
-
Powell, D.J.1
Hajduch, E.2
Kular, G.3
-
52
-
-
3543029821
-
Mechanism of hepatic insulin resistance in non-Alcoholic fatty liver disease
-
Samuel VT, Liu ZX, Qu X., et al. Mechanism of hepatic insulin resistance in non-Alcoholic fatty liver disease. J Biol Chem. 2004; 279: 32345-32353
-
(2004)
J Biol Chem
, vol.279
, pp. 32345-32353
-
-
Samuel, V.T.1
Liu, Z.X.2
Qu, X.3
-
53
-
-
38649124615
-
Activation and dysregulation of the unfolded protein response in nonalcoholic fatty liver disease
-
Puri P, Mirshahi F, Cheung O., et al. Activation and dysregulation of the unfolded protein response in nonalcoholic fatty liver disease. Gastroenterology. 2008; 134: 568-576
-
(2008)
Gastroenterology
, vol.134
, pp. 568-576
-
-
Puri, P.1
Mirshahi, F.2
Cheung, O.3
-
54
-
-
0036302288
-
Expanding the natural history of nonalcoholic steatohepatitis: From cryptogenic cirrhosis to hepatocellular carcinoma
-
Bugianesi E, Leone N, Vanni E., et al. Expanding the natural history of nonalcoholic steatohepatitis: from cryptogenic cirrhosis to hepatocellular carcinoma. Gastroenterology. 2002; 123: 134-140
-
(2002)
Gastroenterology
, vol.123
, pp. 134-140
-
-
Bugianesi, E.1
Leone, N.2
Vanni, E.3
-
55
-
-
10644268512
-
IRS-2 mediates the antiapoptotic effect of insulin in neonatal hepatocytes
-
Valverde AM, Fabregat I, Burks DJ., et al. IRS-2 mediates the antiapoptotic effect of insulin in neonatal hepatocytes. Hepatology. 2004; 40: 1285-1294
-
(2004)
Hepatology
, vol.40
, pp. 1285-1294
-
-
Valverde, A.M.1
Fabregat, I.2
Burks, D.J.3
-
56
-
-
0036165809
-
Tumor necrosis factor alpha promoter polymorphisms and insulin resistance in nonalcoholic fatty liver disease
-
Valenti L, Fracanzani AL, Dongiovanni P., et al. Tumor necrosis factor alpha promoter polymorphisms and insulin resistance in nonalcoholic fatty liver disease. Gastroenterology. 2002; 122: 274-280
-
(2002)
Gastroenterology
, vol.122
, pp. 274-280
-
-
Valenti, L.1
Fracanzani, A.L.2
Dongiovanni, P.3
-
57
-
-
77149168465
-
Genetic variants regulating insulin receptor signalling are associated with the severity of liver damage in patients with non-Alcoholic fatty liver disease
-
Dongiovanni P, Valenti L, Rametta R., et al. Genetic variants regulating insulin receptor signalling are associated with the severity of liver damage in patients with non-Alcoholic fatty liver disease. Gut. 2010; 59: 267-273
-
(2010)
Gut
, vol.59
, pp. 267-273
-
-
Dongiovanni, P.1
Valenti, L.2
Rametta, R.3
-
58
-
-
84939200165
-
Genetic factors in the pathogenesis of nonalcoholic fatty liver and steatohepatitis
-
Dongiovanni P, Romeo S, Valenti L. Genetic factors in the pathogenesis of nonalcoholic fatty liver and steatohepatitis. Biomed Res Int. 2015; 2015: 460190
-
(2015)
Biomed Res Int
, vol.2015
, pp. 460190
-
-
Dongiovanni, P.1
Romeo, S.2
Valenti, L.3
-
59
-
-
84887553152
-
PNPLA3 I148M polymorphism and progressive liver disease
-
Dongiovanni P, Donati B, Fares R., et al. PNPLA3 I148M polymorphism and progressive liver disease. World J Gastroenterol. 2013; 19: 6969-6978
-
(2013)
World J Gastroenterol
, vol.19
, pp. 6969-6978
-
-
Dongiovanni, P.1
Donati, B.2
Fares, R.3
-
60
-
-
84886298620
-
Non-Alcoholic steatohepatitis: A microbiota-driven disease
-
Moschen AR, Kaser S, Tilg H. Non-Alcoholic steatohepatitis: a microbiota-driven disease. Trends Endocrinol Metab. 2013; 24: 537-545
-
(2013)
Trends Endocrinol Metab
, vol.24
, pp. 537-545
-
-
Moschen, A.R.1
Kaser, S.2
Tilg, H.3
-
61
-
-
70349570846
-
The immunopathogenesis of alcoholic and nonalcoholic steatohepatitis: Two triggers for one disease?
-
Valenti L, Fracanzani AL, Fargion S. The immunopathogenesis of alcoholic and nonalcoholic steatohepatitis: two triggers for one disease? Semin Immunopathol. 2009; 31: 359-369
-
(2009)
Semin Immunopathol
, vol.31
, pp. 359-369
-
-
Valenti, L.1
Fracanzani, A.L.2
Fargion, S.3
-
62
-
-
43049095235
-
Mechanism of mitochondrial glutathione-dependent hepatocellular susceptibility to TNF despite NF-kappaB activation
-
Mari M, Colell A, Morales A., et al. Mechanism of mitochondrial glutathione-dependent hepatocellular susceptibility to TNF despite NF-kappaB activation. Gastroenterology. 2008; 134: 1507-1520
-
(2008)
Gastroenterology
, vol.134
, pp. 1507-1520
-
-
Mari, M.1
Colell, A.2
Morales, A.3
-
63
-
-
0035084699
-
Nonalcoholic steatohepatitis: Association of insulin resistance and mitochondrial abnormalities
-
Sanyal AJ, Campbell-Sargent C, Mirshahi F., et al. Nonalcoholic steatohepatitis: association of insulin resistance and mitochondrial abnormalities. Gastroenterology. 2001; 120: 1183-1192
-
(2001)
Gastroenterology
, vol.120
, pp. 1183-1192
-
-
Sanyal, A.J.1
Campbell-Sargent, C.2
Mirshahi, F.3
-
64
-
-
18144444592
-
Defective hepatic mitochondrial respiratory chain in patients with nonalcoholic steatohepatitis
-
Perez-Carreras M, Del Hoyo P, Martin MA., et al. Defective hepatic mitochondrial respiratory chain in patients with nonalcoholic steatohepatitis. Hepatology. 2003; 38: 999-1007
-
(2003)
Hepatology
, vol.38
, pp. 999-1007
-
-
Perez-Carreras, M.1
Del Hoyo, P.2
Martin, M.A.3
-
65
-
-
32044453080
-
Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response
-
Zhang K, Shen X, Wu J., et al. Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response. Cell. 2006; 124: 587-599
-
(2006)
Cell
, vol.124
, pp. 587-599
-
-
Zhang, K.1
Shen, X.2
Wu, J.3
-
66
-
-
84924230659
-
Cellular and molecular functions of hepatic stellate cells in inflammatory responses and liver immunology
-
Weiskirchen R, Tacke F. Cellular and molecular functions of hepatic stellate cells in inflammatory responses and liver immunology. Hepatobiliary Surg Nutr. 2014; 3: 344-363
-
(2014)
Hepatobiliary Surg Nutr
, vol.3
, pp. 344-363
-
-
Weiskirchen, R.1
Tacke, F.2
-
67
-
-
84903996547
-
PNPLA3 has retinyl-palmitate lipase activity in human hepatic stellate cells
-
Pirazzi C, Valenti L, Motta BM., et al. PNPLA3 has retinyl-palmitate lipase activity in human hepatic stellate cells. Hum Mol Genet. 2014; 23: 4077-4085
-
(2014)
Hum Mol Genet
, vol.23
, pp. 4077-4085
-
-
Pirazzi, C.1
Valenti, L.2
Motta, B.M.3
-
68
-
-
84902657591
-
Role of gut microbiota and Toll-like receptors in nonalcoholic fatty liver disease
-
Miura K, Ohnishi H. Role of gut microbiota and Toll-like receptors in nonalcoholic fatty liver disease. World J Gastroenterol. 2014; 20: 7381-7391
-
(2014)
World J Gastroenterol
, vol.20
, pp. 7381-7391
-
-
Miura, K.1
Ohnishi, H.2
-
69
-
-
63349085247
-
Hepatocellular carcinomas in patients with metabolic syndrome often develop without significant liver fibrosis: A pathological analysis
-
Paradis V, Zalinski S, Chelbi E., et al. Hepatocellular carcinomas in patients with metabolic syndrome often develop without significant liver fibrosis: a pathological analysis. Hepatology. 2009; 49: 851-859
-
(2009)
Hepatology
, vol.49
, pp. 851-859
-
-
Paradis, V.1
Zalinski, S.2
Chelbi, E.3
-
70
-
-
84927615859
-
Hepatocellular carcinoma in nonalcoholic fatty liver: Role of environmental and genetic factors
-
Dongiovanni P, Romeo S, Valenti L. Hepatocellular carcinoma in nonalcoholic fatty liver: role of environmental and genetic factors. World J Gastroenterol. 2014; 20: 12945-12955
-
(2014)
World J Gastroenterol
, vol.20
, pp. 12945-12955
-
-
Dongiovanni, P.1
Romeo, S.2
Valenti, L.3
-
71
-
-
84919615360
-
Metformin: From mechanisms of action to therapies
-
Foretz M, Guigas B, Bertrand L., et al. Metformin: from mechanisms of action to therapies. Cell Metab. 2014; 20: 953-966
-
(2014)
Cell Metab
, vol.20
, pp. 953-966
-
-
Foretz, M.1
Guigas, B.2
Bertrand, L.3
-
72
-
-
84862517200
-
Impact of current treatments on liver disease, glucose metabolism and cardiovascular risk in non-Alcoholic fatty liver disease (NAFLD): A systematic review and meta-Analysis of randomised trials
-
Musso G, Cassader M, Rosina F., et al. Impact of current treatments on liver disease, glucose metabolism and cardiovascular risk in non-Alcoholic fatty liver disease (NAFLD): a systematic review and meta-Analysis of randomised trials. Diabetologia. 2012; 55: 885-904
-
(2012)
Diabetologia
, vol.55
, pp. 885-904
-
-
Musso, G.1
Cassader, M.2
Rosina, F.3
-
73
-
-
1642296465
-
Metformin in the treatment of patients with non-Alcoholic steatohepatitis
-
Uygun A, Kadayifci A, Isik AT., et al. Metformin in the treatment of patients with non-Alcoholic steatohepatitis. Aliment Pharmacol Ther. 2004; 19 (5): 537-544
-
(2004)
Aliment Pharmacol Ther
, vol.19
, Issue.5
, pp. 537-544
-
-
Uygun, A.1
Kadayifci, A.2
Isik, A.T.3
-
74
-
-
19144365586
-
A randomized controlled trial of metformin versus Vitamin E or prescriptive diet in nonalcoholic fatty liver disease
-
Bugianesi E, Gentilcore E, Manini R., et al. A randomized controlled trial of metformin versus vitamin E or prescriptive diet in nonalcoholic fatty liver disease. Am J Gastroenterol. 2005; 100 (5): 1082-1090
-
(2005)
Am J Gastroenterol
, vol.100
, Issue.5
, pp. 1082-1090
-
-
Bugianesi, E.1
Gentilcore, E.2
Manini, R.3
-
75
-
-
37549047166
-
Metformin is effective in achieving biochemical response in patients with nonalcoholic fatty liver disease (NAFLD) not responding to lifestyle interventions
-
Duseja A, Das A, Dhiman RK., et al. Metformin is effective in achieving biochemical response in patients with nonalcoholic fatty liver disease (NAFLD) not responding to lifestyle interventions. Ann Hepatol. 2007; 6 (4): 222-226
-
(2007)
Ann Hepatol
, vol.6
, Issue.4
, pp. 222-226
-
-
Duseja, A.1
Das, A.2
Dhiman, R.K.3
-
76
-
-
70350662659
-
Metformin in patients with non-Alcoholic fatty liver disease: A randomized, controlled trial
-
Haukeland JW, Konopski Z, Eggesbo HB., et al. Metformin in patients with non-Alcoholic fatty liver disease: a randomized, controlled trial. Scand J Gastroenterol. 2009; 44 (7): 853-860
-
(2009)
Scand J Gastroenterol
, vol.44
, Issue.7
, pp. 853-860
-
-
Haukeland, J.W.1
Konopski, Z.2
Eggesbo, H.B.3
-
77
-
-
77955470801
-
Metformin versus dietary treatment in nonalcoholic hepatic steatosis: A randomized study
-
Garinis GA, Fruci B, Mazza A., et al. Metformin versus dietary treatment in nonalcoholic hepatic steatosis: a randomized study. Int J Obes. 2010; 34 (8): 1255-1264
-
(2010)
Int J Obes
, vol.34
, Issue.8
, pp. 1255-1264
-
-
Garinis, G.A.1
Fruci, B.2
Mazza, A.3
-
78
-
-
14944359845
-
A pilot study of Vitamin E versus Vitamin E and pioglitazone for the treatment of nonalcoholic steatohepatitis
-
Sanyal AJ, Mofrad PS, Contos MJ., et al. A pilot study of vitamin E versus vitamin E and pioglitazone for the treatment of nonalcoholic steatohepatitis. Clin Gastroenterol Hepatol. 2004; 2 (12): 1107-1115
-
(2004)
Clin Gastroenterol Hepatol
, vol.2
, Issue.12
, pp. 1107-1115
-
-
Sanyal, A.J.1
Mofrad, P.S.2
Contos, M.J.3
-
79
-
-
33751545838
-
A placebo-controlled trial of pioglitazone in subjects with nonalcoholic steatohepatitis
-
Belfort R, Harrison SA, Brown K., et al. A placebo-controlled trial of pioglitazone in subjects with nonalcoholic steatohepatitis. N Engl J Med. 2006; 355 (22): 2297-2307
-
(2006)
N Engl J Med
, vol.355
, Issue.22
, pp. 2297-2307
-
-
Belfort, R.1
Harrison, S.A.2
Brown, K.3
-
80
-
-
53049101877
-
Randomized, placebo-controlled trial of pioglitazone in nondiabetic subjects with nonalcoholic steatohepatitis
-
Aithal GP, Thomas JA, Kaye PV., et al. Randomized, placebo-controlled trial of pioglitazone in nondiabetic subjects with nonalcoholic steatohepatitis. Gastroenterology. 2008; 135 (4): 1176-1184
-
(2008)
Gastroenterology
, vol.135
, Issue.4
, pp. 1176-1184
-
-
Aithal, G.P.1
Thomas, J.A.2
Kaye, P.V.3
-
81
-
-
45549091794
-
Clinical trial: Insulin-sensitizing agents may reduce consequences of insulin resistance in individuals with non-Alcoholic steatohepatitis
-
Idilman R, Mizrak D, Corapcioglu D., et al. Clinical trial: insulin-sensitizing agents may reduce consequences of insulin resistance in individuals with non-Alcoholic steatohepatitis. Aliment Pharmacol Ther. 2008; 28 (2): 200-208
-
(2008)
Aliment Pharmacol Ther
, vol.28
, Issue.2
, pp. 200-208
-
-
Idilman, R.1
Mizrak, D.2
Corapcioglu, D.3
-
82
-
-
46349088361
-
Rosiglitazone for nonalcoholic steatohepatitis: One-year results of the randomized placebo-controlled Fatty Liver Improvement with Rosiglitazone Therapy (FLIRT) Trial
-
Ratziu V, Giral P, Jacqueminet S., et al. Rosiglitazone for nonalcoholic steatohepatitis: one-year results of the randomized placebo-controlled Fatty Liver Improvement with Rosiglitazone Therapy (FLIRT) Trial. Gastroenterology. 2008; 135 (1): 100-110
-
(2008)
Gastroenterology
, vol.135
, Issue.1
, pp. 100-110
-
-
Ratziu, V.1
Giral, P.2
Jacqueminet, S.3
-
83
-
-
74349125502
-
Efficacy of insulin-sensitizing agents in nonalcoholic fatty liver disease
-
Omer Z, Cetinkalp S, Akyildiz M., et al. Efficacy of insulin-sensitizing agents in nonalcoholic fatty liver disease. Eur J Gastroenterol Hepatol. 2010; 22 (1): 18-23
-
(2010)
Eur J Gastroenterol Hepatol
, vol.22
, Issue.1
, pp. 18-23
-
-
Omer, Z.1
Cetinkalp, S.2
Akyildiz, M.3
-
84
-
-
77951874018
-
Pioglitazone, Vitamin E, or placebo for nonalcoholic steatohepatitis
-
Sanyal AJ, Chalasani N, Kowdley KV., et al. Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis. N Engl J Med. 2010; 362 (18): 1675-1685
-
(2010)
N Engl J Med
, vol.362
, Issue.18
, pp. 1675-1685
-
-
Sanyal, A.J.1
Chalasani, N.2
Kowdley, K.V.3
-
85
-
-
0033927667
-
Cellular mechanisms of insulin resistance
-
Shulman GI. Cellular mechanisms of insulin resistance. J Clin Invest. 2000; 106: 171-176
-
(2000)
J Clin Invest
, vol.106
, pp. 171-176
-
-
Shulman, G.I.1
-
86
-
-
84945185644
-
Comparative effectiveness of pharmacological interventions for non-Alcoholic steatohepatitis: A systematic review and network meta-Analysis
-
Singh S, Khera R, Allen AM., et al. Comparative effectiveness of pharmacological interventions for non-Alcoholic steatohepatitis: a systematic review and network meta-Analysis. Hepatology. 2015;62(5):1417-1432
-
(2015)
Hepatology
, vol.62
, Issue.5
, pp. 1417-1432
-
-
Singh, S.1
Khera, R.2
Allen, A.M.3
-
87
-
-
84860375795
-
Thiazolidinediones and PPARgamma agonists: Time for a reassessment
-
Cariou B, Charbonnel B, Staels B. Thiazolidinediones and PPARgamma agonists: time for a reassessment. Trends Endocrinol Metab. 2012; 23: 205-215
-
(2012)
Trends Endocrinol Metab
, vol.23
, pp. 205-215
-
-
Cariou, B.1
Charbonnel, B.2
Staels, B.3
-
88
-
-
84859157277
-
Roles of PPARs in NAFLD: Potential therapeutic targets
-
Tailleux A, Wouters K, Staels B. Roles of PPARs in NAFLD: potential therapeutic targets. Biochim Biophys Acta. 2012; 1821: 809-818
-
(2012)
Biochim Biophys Acta
, vol.1821
, pp. 809-818
-
-
Tailleux, A.1
Wouters, K.2
Staels, B.3
-
89
-
-
84929266699
-
Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-Alcoholic steatohepatitis (FLINT): A multicentre, randomised, placebo-controlled trial
-
Neuschwander-Tetri BA, Loomba R, Sanyal AJ., et al. Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-Alcoholic steatohepatitis (FLINT): a multicentre, randomised, placebo-controlled trial. Lancet. 2015; 385: 956-965
-
(2015)
Lancet
, vol.385
, pp. 956-965
-
-
Neuschwander-Tetri, B.A.1
Loomba, R.2
Sanyal, A.J.3
-
90
-
-
84893649359
-
New peroxisome proliferator-Activated receptor agonists: Potential treatments for atherogenic dyslipidemia and non-Alcoholic fatty liver disease
-
Sahebkar A, Chew GT, Watts GF. New peroxisome proliferator-Activated receptor agonists: potential treatments for atherogenic dyslipidemia and non-Alcoholic fatty liver disease. Expert Opin Pharmacother. 2014; 15: 493-503
-
(2014)
Expert Opin Pharmacother
, vol.15
, pp. 493-503
-
-
Sahebkar, A.1
Chew, G.T.2
Watts, G.F.3
-
91
-
-
78649633125
-
Hepatic insulin resistance is associated with increased apoptosis and fibrogenesis in nonalcoholic steatohepatitis and chronic hepatitis C
-
Garcia-Monzon C, Lo Iacono O, Mayoral R., et al. Hepatic insulin resistance is associated with increased apoptosis and fibrogenesis in nonalcoholic steatohepatitis and chronic hepatitis C. J Hepatol. 2011; 54: 142-152
-
(2011)
J Hepatol
, vol.54
, pp. 142-152
-
-
Garcia-Monzon, C.1
Lo Iacono, O.2
Mayoral, R.3
-
93
-
-
0345655291
-
Insulin resistance is associated with chronic hepatitis C virus infection and fibrosis progression [corrected]
-
Hui JM, Sud A, Farrell GC., et al. Insulin resistance is associated with chronic hepatitis C virus infection and fibrosis progression [corrected]. Gastroenterology. 2003; 125: 1695-1704
-
(2003)
Gastroenterology
, vol.125
, pp. 1695-1704
-
-
Hui, J.M.1
Sud, A.2
Farrell, G.C.3
-
94
-
-
84868203343
-
Sustained virological response prevents the development of insulin resistance in patients with chronic hepatitis C
-
Aghemo A, Prati GM, Rumi MG., et al. Sustained virological response prevents the development of insulin resistance in patients with chronic hepatitis C. Hepatology. 2012; 56: 1681-1687
-
(2012)
Hepatology
, vol.56
, pp. 1681-1687
-
-
Aghemo, A.1
Prati, G.M.2
Rumi, M.G.3
-
95
-
-
40149089262
-
Hepatitis C virus core protein upregulates serine phosphorylation of insulin receptor substrate-1 and impairs the downstream akt/protein kinase B signaling pathway for insulin resistance
-
Banerjee S, Saito K, Ait-Goughoulte M., et al. Hepatitis C virus core protein upregulates serine phosphorylation of insulin receptor substrate-1 and impairs the downstream akt/protein kinase B signaling pathway for insulin resistance. J Virol. 2008; 82: 2606-2612
-
(2008)
J Virol
, vol.82
, pp. 2606-2612
-
-
Banerjee, S.1
Saito, K.2
Ait-Goughoulte, M.3
-
96
-
-
43549124805
-
Insulin resistance and diabetes increase fibrosis in the liver of patients with genotype 1 HCV infection
-
Petta S, Camma C, Di Marco V., et al. Insulin resistance and diabetes increase fibrosis in the liver of patients with genotype 1 HCV infection. Am J Gastroenterol. 2008; 103: 1136-1144
-
(2008)
Am J Gastroenterol
, vol.103
, pp. 1136-1144
-
-
Petta, S.1
Camma, C.2
Di Marco, V.3
-
97
-
-
0034802171
-
High glucose and hyperinsulinemia stimulate connective tissue growth factor expression: A potential mechanism involved in progression to fibrosis in nonalcoholic steatohepatitis
-
Paradis V, Perlemuter G, Bonvoust F., et al. High glucose and hyperinsulinemia stimulate connective tissue growth factor expression: a potential mechanism involved in progression to fibrosis in nonalcoholic steatohepatitis. Hepatology. 2001; 34: 738-744
-
(2001)
Hepatology
, vol.34
, pp. 738-744
-
-
Paradis, V.1
Perlemuter, G.2
Bonvoust, F.3
-
98
-
-
33646529840
-
Relationship between steatosis, inflammation, and fibrosis in chronic hepatitis C: A meta-Analysis of individual patient data
-
Leandro G, Mangia A, Hui J., et al. Relationship between steatosis, inflammation, and fibrosis in chronic hepatitis C: a meta-Analysis of individual patient data. Gastroenterology. 2006; 130: 1636-1642
-
(2006)
Gastroenterology
, vol.130
, pp. 1636-1642
-
-
Leandro, G.1
Mangia, A.2
Hui, J.3
-
99
-
-
79960824576
-
Impact of insulin resistance on sustained response in HCV patients treated with pegylated interferon and ribavirin: A meta-Analysis
-
Deltenre P, Louvet A, Lemoine M., et al. Impact of insulin resistance on sustained response in HCV patients treated with pegylated interferon and ribavirin: a meta-Analysis. J Hepatol. 2011; 55: 1187-1194
-
(2011)
J Hepatol
, vol.55
, pp. 1187-1194
-
-
Deltenre, P.1
Louvet, A.2
Lemoine, M.3
-
100
-
-
46349099383
-
Pioglitazone in chronic hepatitis C not responding to pegylated interferon-Alpha and ribavirin
-
Overbeck K., et al. Pioglitazone in chronic hepatitis C not responding to pegylated interferon-Alpha and ribavirin. J Hepatol. 2008; 49 (2): 295-298
-
(2008)
J Hepatol
, vol.49
, Issue.2
, pp. 295-298
-
-
Overbeck, K.1
-
101
-
-
77950602195
-
Pioglitazone improves virological response to peginterferon alpha-2b/ribavirin combination therapy in hepatitis C genotype 4 patients with insulin resistance
-
Khattab M., et al. Pioglitazone improves virological response to peginterferon alpha-2b/ribavirin combination therapy in hepatitis C genotype 4 patients with insulin resistance. Liver Int. 2010; 30 (3): 447-454
-
(2010)
Liver Int
, vol.30
, Issue.3
, pp. 447-454
-
-
Khattab, M.1
-
102
-
-
84857891323
-
Pioglitazone decreases hepatitis C viral load in overweight, treatment naive, genotype 4 infected-patients: A pilot study
-
Chojkier M., et al. Pioglitazone decreases hepatitis C viral load in overweight, treatment naive, genotype 4 infected-patients: a pilot study. PLoS One. 2012; 7 (3): e31516
-
(2012)
PLoS One
, vol.7
, Issue.3
, pp. e31516
-
-
Chojkier, M.1
-
103
-
-
84864348299
-
Chronic hepatitis C genotype 1 patients with insulin resistance treated with pioglitazone and peginterferon alpha-2a plus ribavirin
-
Harrison SA., et al. Chronic hepatitis C genotype 1 patients with insulin resistance treated with pioglitazone and peginterferon alpha-2a plus ribavirin. Hepatology. 2012; 56 (2): 464-473
-
(2012)
Hepatology
, vol.56
, Issue.2
, pp. 464-473
-
-
Harrison, S.A.1
-
104
-
-
72549104493
-
Treatment of insulin resistance with metformin in naive genotype 1 chronic hepatitis C patients receiving peginterferon alfa-2a plus ribavirin
-
Romero-Gomez M., et al. Treatment of insulin resistance with metformin in naive genotype 1 chronic hepatitis C patients receiving peginterferon alfa-2a plus ribavirin. Hepatology. 2009; 50 (6): 1702-1708
-
(2009)
Hepatology
, vol.50
, Issue.6
, pp. 1702-1708
-
-
Romero-Gomez, M.1
-
105
-
-
84934279409
-
Efficacy of adding metformin to pegylated interferon and ribavirin in treatment naive patients with chronic hepatitis C: A randomized double-blind controlled trial
-
Sharifi AH., et al. Efficacy of adding metformin to pegylated interferon and ribavirin in treatment naive patients with chronic hepatitis C: a randomized double-blind controlled trial. Middle East J Dig Dis. 2014; 6 (1): 13-17
-
(2014)
Middle East J Dig Dis
, vol.6
, Issue.1
, pp. 13-17
-
-
Sharifi, A.H.1
-
106
-
-
58249083392
-
Metabolic syndrome increases the risk of liver cirrhosis in chronic hepatitis B
-
Wong GL, Wong VW, Choi PC., et al. Metabolic syndrome increases the risk of liver cirrhosis in chronic hepatitis B. Gut. 2009; 58: 111-117
-
(2009)
Gut
, vol.58
, pp. 111-117
-
-
Wong, G.L.1
Wong, V.W.2
Choi, P.C.3
-
107
-
-
84884978594
-
Patatin-like phospholipase domain-containing 3 I148M affects liver steatosis in patients with chronic hepatitis B
-
Vigano M, Valenti L, Lampertico P., et al. Patatin-like phospholipase domain-containing 3 I148M affects liver steatosis in patients with chronic hepatitis B. Hepatology. 2013; 58: 1245-1252
-
(2013)
Hepatology
, vol.58
, pp. 1245-1252
-
-
Vigano, M.1
Valenti, L.2
Lampertico, P.3
-
108
-
-
84945484423
-
Insulin resistance in clinical and experimental alcoholic liver disease
-
Carr RM, Correnti J. Insulin resistance in clinical and experimental alcoholic liver disease. Ann N Y Acad Sci. 2015;1353(1):1-20
-
(2015)
Ann N y Acad Sci
, vol.1353
, Issue.1
, pp. 1-20
-
-
Carr, R.M.1
Correnti, J.2
-
109
-
-
15544382574
-
Diabetes increases the risk of hepatocellular carcinoma in the United States: A population based case control study
-
Davila JA, Morgan RO, Shaib Y., et al. Diabetes increases the risk of hepatocellular carcinoma in the United States: a population based case control study. Gut. 2005; 54: 533-539
-
(2005)
Gut
, vol.54
, pp. 533-539
-
-
Davila, J.A.1
Morgan, R.O.2
Shaib, Y.3
-
111
-
-
84934285880
-
Systematic review: Preventive and therapeutic applications of metformin in liver disease
-
Bhat A, Sebastiani G, Bhat M. Systematic review: preventive and therapeutic applications of metformin in liver disease. World J Hepatol. 2015; 7: 1652-1659
-
(2015)
World J Hepatol
, vol.7
, pp. 1652-1659
-
-
Bhat, A.1
Sebastiani, G.2
Bhat, M.3
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