-
1
-
-
0018822167
-
Insulin resistance in soleus muscle from obese zucker rats Involvement of several defective sites
-
Crettaz M, Prentki M, Zaninetti D, Jeanrenaud B: Insulin resistance in soleus muscle from obese zucker rats. Involvement of several defective sites. Biochem J 1980; 186: 525-534.
-
(1980)
Biochem J
, vol.186
, pp. 525-534
-
-
Crettaz, M.1
Prentki, M.2
Zaninetti, D.3
Jeanrenaud, B.4
-
2
-
-
27744507722
-
Insulin resistance and muscle strength in olDer persons
-
Abbatecola AM, Ferrucci L, Ceda G, Russo CR, Lauretani F, Bandinelli S, Barbieri M, Valenti G, Paolisso G: Insulin resistance and muscle strength in olDer persons. J Gerontol A Biol Sci Med Sci 2005; 60: 1278-1282.
-
(2005)
J Gerontol A Biol Sci Med Sci
, vol.60
, pp. 1278-1282
-
-
Abbatecola, A.M.1
Ferrucci, L.2
Ceda, G.3
Russo, C.R.4
Lauretani, F.5
Bandinelli, S.6
Barbieri, M.7
Valenti, G.8
Paolisso, G.9
-
3
-
-
0018571214
-
Insulin deficiency and insulin resistance interaction in diabetes: Estimation of their relative contribution by feedback analysis from basal plasma insulin and glucose concentrations
-
Turner RC, Holman RR, Matthews D, Hockaday TD, Peto J: Insulin deficiency and insulin resistance interaction in diabetes: Estimation of their relative contribution by feedback analysis from basal plasma insulin and glucose concentrations. Metabolism 1979; 28: 1086-1096.
-
(1979)
Metabolism
, vol.28
, pp. 1086-1096
-
-
Turner, R.C.1
Holman, R.R.2
Matthews, D.3
Hockaday, T.D.4
Peto, J.5
-
4
-
-
33745267713
-
Prevalence of type 2 diabetes mellitus of chinese populations in mainland china, hong kong, and taiwan
-
Wong KC, Wang Z: Prevalence of type 2 diabetes mellitus of chinese populations in mainland china, hong kong, and taiwan. Diabetes Res Clin Pract 2006; 73: 126-134.
-
(2006)
Diabetes Res Clin Pract
, vol.73
, pp. 126-134
-
-
Wong, K.C.1
Wang, Z.2
-
5
-
-
77954162737
-
The economic burden of diabetes
-
Dall TM, Zhang Y, Chen YJ, Quick WW, Yang WG, Fogli J: The economic burden of diabetes. Health Aff (Millwood) 2010; 29: 297-303.
-
(2010)
Health Aff (Millwood)
, vol.29
, pp. 297-303
-
-
Dall, T.M.1
Zhang, Y.2
Chen, Y.J.3
Quick, W.W.4
Yang, W.G.5
Fogli, J.6
-
6
-
-
84906793931
-
Differences in skeletal and non-skeletal factors in a diverse sample of men with and without type 2 diabetes mellitus
-
Akeroyd JM, Suarez EA, Bartali B, Chiu GR, Yang M, Schwartz AV, Araujo AB: Differences in skeletal and non-skeletal factors in a diverse sample of men with and without type 2 diabetes mellitus. J Diabetes Complications 2014
-
(2014)
J Diabetes Complications
-
-
Akeroyd, J.M.1
Suarez, E.A.2
Bartali, B.3
Chiu, G.R.4
Yang, M.5
Schwartz, A.V.6
Araujo, A.B.7
-
7
-
-
80455143206
-
Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans
-
Timmers S, Konings E, Bilet L, Houtkooper RH, Van de Weijer T, Goossens GH, Hoeks J, Van Der Krieken S, Ryu D, Kersten S, Moonen-Kornips E, Hesselink MK, Kunz I, Schrauwen-HinDerling VB, Blaak EE, Auwerx J, Schrauwen P: Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans. Cell Metab 2011; 14: 612-622.
-
(2011)
Cell Metab
, vol.14
, pp. 612-622
-
-
Timmers, S.1
Konings, E.2
Bilet, L.3
Houtkooper, R.H.4
Van De Weijer, T.5
Goossens, G.H.6
Hoeks, J.7
Van Der Krieken, S.8
Ryu, D.9
Kersten, S.10
Moonen-Kornips, E.11
Hesselink, M.K.12
Kunz, I.13
Schrauwen-Hinderling, V.B.14
Blaak, E.E.15
Auwerx, J.16
Schrauwen, P.17
-
8
-
-
0028869749
-
Effects of strength and endurance training on thigh and leg muscle mass and composition in elDerly women
-
Sipila S, Suominen H: Effects of strength and endurance training on thigh and leg muscle mass and composition in elDerly women. J Appl Physiol (1985) 1995; 78: 334-340.
-
(1985)
J Appl Physiol
, vol.1995
, Issue.78
, pp. 334-340
-
-
Sipila, S.1
Suominen, H.2
-
9
-
-
0842310044
-
Strength training increases insulin-mediated glucose uptake, glut4 content, and insulin signaling in skeletal muscle in patients with type 2 diabetes
-
Holten MK, Zacho M, Gaster M, Juel C, Wojtaszewski JF, Dela F: Strength training increases insulin-mediated glucose uptake, glut4 content, and insulin signaling in skeletal muscle in patients with type 2 diabetes. Diabetes 2004; 53: 294-305.
-
(2004)
Diabetes
, vol.53
, pp. 294-305
-
-
Holten, M.K.1
Zacho, M.2
Gaster, M.3
Juel, C.4
Wojtaszewski, J.F.5
Dela, F.6
-
11
-
-
0141566914
-
Invited review: Aging and sarcopenia
-
Doherty TJ: Invited review: Aging and sarcopenia. J Appl Physiol (1985) 2003; 95: 1717-1727.
-
(1985)
J Appl Physiol
, vol.2003
, Issue.95
, pp. 1717-1727
-
-
Doherty, T.J.1
-
12
-
-
33846676157
-
Physical activity in u.S. Adults with diabetes and at risk for developing diabetes 2003
-
Morrato EH, Hill JO, Wyatt HR, Ghushchyan V, SulliVan PW: Physical activity in u.S. Adults with diabetes and at risk for developing diabetes, 2003. Diabetes Care 2007; 30: 203-209.
-
(2007)
Diabetes Care
, vol.30
, pp. 203-209
-
-
Morrato, E.H.1
Hill, J.O.2
Wyatt, H.R.3
Ghushchyan, V.4
Sullivan, P.W.5
-
13
-
-
84905176929
-
Short-term calorie restriction improves glucose homeostasis in old rats: Involvement of ampk
-
Pires RC, Souza EE, Vanzela EC, Ribeiro RA, Silva-Santos JC, Carneiro EM, Boschero AC, Amaral ME: Short-term calorie restriction improves glucose homeostasis in old rats: Involvement of ampk. Appl Physiol Nutr Metab 2014; 39: 895-901.
-
(2014)
Appl Physiol Nutr Metab
, vol.39
, pp. 895-901
-
-
Pires, R.C.1
Souza, E.E.2
Vanzela, E.C.3
Ribeiro, R.A.4
Silva-Santos, J.C.5
Carneiro, E.M.6
Boschero, A.C.7
Amaral, M.E.8
-
14
-
-
33746419647
-
Effect of calorie restriction with or without exercise on insulin sensitivity, beta-cell function, fat cell size, and ectopic lipid in overweight subjects
-
Larson-Meyer DE, Heilbronn LK, Redman LM, Newcomer BR, Frisard MI, Anton S, Smith SR, Alfonso A, Ravussin E: Effect of calorie restriction with or without exercise on insulin sensitivity, beta-cell function, fat cell size, and ectopic lipid in overweight subjects. Diabetes Care 2006; 29: 1337-1344.
-
(2006)
Diabetes Care
, vol.29
, pp. 1337-1344
-
-
Larson-Meyer, D.E.1
Heilbronn, L.K.2
Redman, L.M.3
Newcomer, B.R.4
Frisard, M.I.5
Anton, S.6
Smith, S.R.7
Alfonso, A.8
Ravussin, E.9
-
15
-
-
33845399894
-
Resveratrol improves mitochondrial function and protects against metabolic disease by activating sirt1 and pgc-1alpha
-
Lagouge M, Argmann C, Gerhart-Hines Z, Meziane H, Lerin C, Daussin F, Messadeq N, Milne J, Lambert P, Elliott P, Geny B, Laakso M, Puigserver P, Auwerx J: Resveratrol improves mitochondrial function and protects against metabolic disease by activating sirt1 and pgc-1alpha. Cell 2006; 127: 1109-1122.
-
(2006)
Cell
, vol.127
, pp. 1109-1122
-
-
Lagouge, M.1
Argmann, C.2
Gerhart-Hines, Z.3
Meziane, H.4
Lerin, C.5
Daussin, F.6
Messadeq, N.7
Milne, J.8
Lambert, P.9
Elliott, P.10
Geny, B.11
Laakso, M.12
Puigserver, P.13
Auwerx, J.14
-
16
-
-
48349110303
-
A low dose of dietary resveratrol partially mimics caloric restriction and retards aging parameters in mice
-
Barger JL, Kayo T, Vann JM, Arias EB, Wang J, Hacker TA, Wang Y, RaeDerstorff D, Morrow JD, Leeuwenburgh C, Allison DB, Saupe KW, Cartee GD, Weindruch R, Prolla TA: A low dose of dietary resveratrol partially mimics caloric restriction and retards aging parameters in mice. PLoS One 2008; 3: e2264.
-
(2008)
PLoS One
, vol.3
, pp. e2264
-
-
Barger, J.L.1
Kayo, T.2
Vann, J.M.3
Arias, E.B.4
Wang, J.5
Hacker, T.A.6
Wang, Y.7
Raederstorff, D.8
Morrow, J.D.9
Leeuwenburgh, C.10
Allison, D.B.11
Saupe, K.W.12
Cartee, G.D.13
Weindruch, R.14
Prolla, T.A.15
-
17
-
-
79961004321
-
Signalling by insulin and igf receptors: Supporting acts and new players
-
Siddle K: Signalling by insulin and igf receptors: Supporting acts and new players. J Mol Endocrinol 2011; 47: R1-10.
-
(2011)
J Mol Endocrinol
, vol.47
, pp. R1-10
-
-
Siddle, K.1
-
18
-
-
84907413305
-
Defect of insulin signal in peripheral tissues: Important role of ceramide
-
Hage Hassan R, Bourron O, Hajduch E: Defect of insulin signal in peripheral tissues: Important role of ceramide. World J Diabetes 2014; 5: 244-257.
-
(2014)
World J Diabetes
, vol.5
, pp. 244-257
-
-
Hage Hassan, R.1
Bourron, O.2
Hajduch, E.3
-
19
-
-
0035044213
-
Clinical review 125: The insulin receptor and its cellular targets
-
Kido Y, Nakae J, Accili D: Clinical review 125: The insulin receptor and its cellular targets. J Clin Endocrinol Metab 2001; 86: 972-979.
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 972-979
-
-
Kido, Y.1
Nakae, J.2
Accili, D.3
-
20
-
-
84866122780
-
Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins irs1 and irs2
-
Copps KD, White MF: Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins irs1 and irs2. Diabetologia 2012; 55: 2565-2582.
-
(2012)
Diabetologia
, vol.55
, pp. 2565-2582
-
-
Copps, K.D.1
White, M.F.2
-
21
-
-
84911863692
-
Mechanistic target of rapamycin (mtor): A point of convergence in the action of insulin/igf-1 and g protein-coupled receptor agonists in pancreatic cancer cells
-
Rozengurt E: Mechanistic target of rapamycin (mtor): A point of convergence in the action of insulin/igf-1 and g protein-coupled receptor agonists in pancreatic cancer cells. Front Physiol 2014; 5: 357.
-
(2014)
Front Physiol
, vol.5
, pp. 357
-
-
Rozengurt, E.1
-
22
-
-
13844312400
-
Phosphorylation and regulation of akt/pkb by the rictor-mtor complex
-
Sarbassov DD, Guertin DA, Ali SM, Sabatini DM: Phosphorylation and regulation of akt/pkb by the rictor-mtor complex. Science 2005; 307: 1098-1101.
-
(2005)
Science
, vol.307
, pp. 1098-1101
-
-
Sarbassov, D.D.1
Guertin, D.A.2
Ali, S.M.3
Sabatini, D.M.4
-
23
-
-
79953216041
-
Evidence for direct activation of mtorc2 kinase activity by phosphatidylinositol 3, 4, 5-trisphosphate
-
Gan X, Wang J, Su B, Wu D: Evidence for direct activation of mtorc2 kinase activity by phosphatidylinositol 3, 4, 5-trisphosphate. J Biol Chem 2011; 286: 10998-11002.
-
(2011)
J Biol Chem
, vol.286
, pp. 10998-11002
-
-
Gan, X.1
Wang, J.2
Su, B.3
Wu, D.4
-
24
-
-
77956244443
-
Hepatic foxo1 ablation exacerbates lipid abnormalities during hyperglycemia
-
Haeusler RA, Han S, Accili D: Hepatic foxo1 ablation exacerbates lipid abnormalities during hyperglycemia. J Biol Chem 2010; 285: 26861-26868.
-
(2010)
J Biol Chem
, vol.285
, pp. 26861-26868
-
-
Haeusler, R.A.1
Han, S.2
Accili, D.3
-
25
-
-
84874677456
-
Independent and combined effects of acute physiological hyperglycaemia and hyperinsulinaemia on metabolic gene expression in human skeletal muscle
-
Tsintzas K, Norton L, Chokkalingam K, Nizamani N, Cooper S, Stephens F, Billeter R, Bennett A: Independent and combined effects of acute physiological hyperglycaemia and hyperinsulinaemia on metabolic gene expression in human skeletal muscle. Clin Sci (Lond) 2013; 124: 675-684.
-
(2013)
Clin Sci (Lond)
, vol.124
, pp. 675-684
-
-
Tsintzas, K.1
Norton, L.2
Chokkalingam, K.3
Nizamani, N.4
Cooper, S.5
Stephens, F.6
Billeter, R.7
Bennett, A.8
-
26
-
-
0036203155
-
Prolonged glucose infusion into conscious rats inhibits early steps in insulin signalling and induces translocation of glut4 and protein kinase c in skeletal muscle
-
Houdali B, Nguyen V, Ammon HP, Haap M, Schechinger W, Machicao F, Rett K, Haring HU, Schleicher ED: Prolonged glucose infusion into conscious rats inhibits early steps in insulin signalling and induces translocation of glut4 and protein kinase c in skeletal muscle. Diabetologia 2002; 45: 356-368.
-
(2002)
Diabetologia
, vol.45
, pp. 356-368
-
-
Houdali, B.1
Nguyen, V.2
Ammon, H.P.3
Haap, M.4
Schechinger, W.5
Machicao, F.6
Rett, K.7
Haring, H.U.8
Schleicher, E.D.9
-
27
-
-
0036788293
-
Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes
-
Kelley DE, He J, Menshikova EV, Ritov VB: Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes. Diabetes 2002; 51: 2944-2950.
-
(2002)
Diabetes
, vol.51
, pp. 2944-2950
-
-
Kelley, D.E.1
He, J.2
Menshikova, E.V.3
Ritov, V.B.4
-
28
-
-
0038025371
-
Mitochondrial dysfunction in the elDerly: Possible role in insulin resistance
-
Petersen KF, Befroy D, Dufour S, Dziura J, Ariyan C, Rothman DL, DiPietro L, Cline GW, Shulman GI: Mitochondrial dysfunction in the elDerly: Possible role in insulin resistance. Science 2003; 300: 1140-1142.
-
(2003)
Science
, vol.300
, pp. 1140-1142
-
-
Petersen, K.F.1
Befroy, D.2
Dufour, S.3
Dziura, J.4
Ariyan, C.5
Rothman, D.L.6
Dipietro, L.7
Cline, G.W.8
Shulman, G.I.9
-
29
-
-
79751496044
-
Berberine improves glucose metabolism in diabetic rats by inhibition of hepatic gluconeogenesis
-
Xia X, Yan J, Shen Y, Tang K, Yin J, Zhang Y, Yang D, Liang H, Ye J, Weng J: Berberine improves glucose metabolism in diabetic rats by inhibition of hepatic gluconeogenesis. PLoS One 2011; 6: e16556.
-
(2011)
PLoS One
, vol.6
, pp. e16556
-
-
Xia, X.1
Yan, J.2
Shen, Y.3
Tang, K.4
Yin, J.5
Zhang, Y.6
Yang, D.7
Liang, H.8
Ye, J.9
Weng, J.10
-
30
-
-
84871426886
-
The ubiquitin ligase mul1 induces mitophagy in skeletal muscle in response to muscle-wasting stimuli
-
Lokireddy S, Wijesoma IW, Teng S, Bonala S, Gluckman PD, McFarlane C, Sharma M, Kambadur R: The ubiquitin ligase mul1 induces mitophagy in skeletal muscle in response to muscle-wasting stimuli. Cell Metab 2012; 16: 613-624.
-
(2012)
Cell Metab
, vol.16
, pp. 613-624
-
-
Lokireddy, S.1
Wijesoma, I.W.2
Teng, S.3
Bonala, S.4
Gluckman, P.D.5
McFarlane, C.6
Sharma, M.7
Kambadur, R.8
-
31
-
-
84890564793
-
Hepatitis c virus dysregulates glucose homeostasis by a dual mechanism involving induction of pgc1alpha and dephosphorylation of foxo1
-
Bernsmeier C, Calabrese D, Heim MH, Duong HT: Hepatitis c virus dysregulates glucose homeostasis by a dual mechanism involving induction of pgc1alpha and dephosphorylation of foxo1. J Viral Hepat 2014; 21: 9-18.
-
(2014)
J Viral Hepat
, vol.21
, pp. 9-18
-
-
Bernsmeier, C.1
Calabrese, D.2
Heim, M.H.3
Duong, H.T.4
-
32
-
-
84858334561
-
Pgc-1alpha encoded by the ppargc1a gene regulates oxidative energy metabolism in equine skeletal muscle during exercise
-
Eivers SS, McGivney BA, Gu J, MacHugh DE, Katz LM, Hill EW: Pgc-1alpha encoded by the ppargc1a gene regulates oxidative energy metabolism in equine skeletal muscle during exercise. Anim Genet 2012; 43: 153-162.
-
(2012)
Anim Genet
, vol.43
, pp. 153-162
-
-
Eivers, S.S.1
McGivney, B.A.2
Gu, J.3
MacHugh, D.E.4
Katz, L.M.5
Hill, E.W.6
-
33
-
-
84863549071
-
Foxo1 in the ventromedial hypothalamus regulates energy balance
-
Kim KW, Donato J, Jr., Berglund ED, Choi YH, Kohno D, Elias CF, Depinho RA, Elmquist JK: Foxo1 in the ventromedial hypothalamus regulates energy balance. J Clin Invest 2012; 122: 2578-2589.
-
(2012)
J Clin Invest
, vol.122
, pp. 2578-2589
-
-
Kim, K.W.1
Donato, J.2
Berglund, E.D.3
Choi, Y.H.4
Kohno, D.5
Elias, C.F.6
Depinho, R.A.7
Elmquist, J.K.8
-
34
-
-
78049448761
-
Mapk phosphatase-3 promotes hepatic gluconeogenesis through dephosphorylation of forkhead box o1 in mice
-
Wu Z, Jiao P, Huang X, Feng B, Feng Y, Yang S, Hwang P, Du J, Nie Y, Xiao G, Xu H: Mapk phosphatase-3 promotes hepatic gluconeogenesis through dephosphorylation of forkhead box o1 in mice. J Clin Invest 2010; 120: 3901-3911.
-
(2010)
J Clin Invest
, vol.120
, pp. 3901-3911
-
-
Wu, Z.1
Jiao, P.2
Huang, X.3
Feng, B.4
Feng, Y.5
Yang, S.6
Hwang, P.7
Du, J.8
Nie, Y.9
Xiao, G.10
Xu, H.11
-
35
-
-
84903385943
-
Foxo1-dependent up-regulation of map kinase phosphatase 3 (mkp-3) mediates glucocorticoid-induced hepatic lipid accumulation in mice
-
Feng B, He Q, Xu H: Foxo1-dependent up-regulation of map kinase phosphatase 3 (mkp-3) mediates glucocorticoid-induced hepatic lipid accumulation in mice. Mol Cell Endocrinol 2014; 393: 46-55.
-
(2014)
Mol Cell Endocrinol
, vol.393
, pp. 46-55
-
-
Feng, B.1
He, Q.2
Xu, H.3
-
36
-
-
84879559745
-
Hepatic erk activity plays a role in energy metabolism
-
Jiao P, Feng B, Li Y, He Q, Xu H: Hepatic erk activity plays a role in energy metabolism. Mol Cell Endocrinol 2013; 375: 157-166.
-
(2013)
Mol Cell Endocrinol
, vol.375
, pp. 157-166
-
-
Jiao, P.1
Feng, B.2
Li, Y.3
He, Q.4
Xu, H.5
-
37
-
-
77249156847
-
Interdependence of ampk and sirt1 for metabolic adaptation to fasting and exercise in skeletal muscle
-
Canto C, Jiang LQ, Deshmukh AS, Mataki C, Coste A, Lagouge M, Zierath JR, Auwerx J: Interdependence of ampk and sirt1 for metabolic adaptation to fasting and exercise in skeletal muscle. Cell Metab 2010; 11: 213-219.
-
(2010)
Cell Metab
, vol.11
, pp. 213-219
-
-
Canto, C.1
Jiang, L.Q.2
Deshmukh, A.S.3
Mataki, C.4
Coste, A.5
Lagouge, M.6
Zierath, J.R.7
Auwerx, J.8
-
38
-
-
66649100810
-
Muscle-specific overexpression of heparin-binding epiDermal growth factor-like growth factor increases peripheral glucose disposal and insulin sensitivity
-
Fukatsu Y, Noguchi T, Hosooka T, Ogura T, Kotani K, Abe T, Shibakusa T, Inoue K, Sakai M, Tobimatsu K, Inagaki K, Yoshioka T, Matsuo M, Nakae J, Matsuki Y, Hiramatsu R, Kaku K, Okamura H, Fushiki T, Kasuga M: Muscle-specific overexpression of heparin-binding epiDermal growth factor-like growth factor increases peripheral glucose disposal and insulin sensitivity. Endocrinology 2009; 150: 2683-2691.
-
(2009)
Endocrinology
, vol.150
, pp. 2683-2691
-
-
Fukatsu, Y.1
Noguchi, T.2
Hosooka, T.3
Ogura, T.4
Kotani, K.5
Abe, T.6
Shibakusa, T.7
Inoue, K.8
Sakai, M.9
Tobimatsu, K.10
Inagaki, K.11
Yoshioka, T.12
Matsuo, M.13
Nakae, J.14
Matsuki, Y.15
Hiramatsu, R.16
Kaku, K.17
Okamura, H.18
Fushiki, T.19
Kasuga, M.20
more..
-
39
-
-
33749338109
-
Insulin regulation of skeletal muscle pdk4 mrna expression is impaired in acute insulin-resistant states
-
Kim YI, Lee FN, Choi WS, Lee S, Youn JH: Insulin regulation of skeletal muscle pdk4 mrna expression is impaired in acute insulin-resistant states. Diabetes 2006; 55: 2311-2317.
-
(2006)
Diabetes
, vol.55
, pp. 2311-2317
-
-
Kim, Y.I.1
Lee, F.N.2
Choi, W.S.3
Lee, S.4
Youn, J.H.5
-
40
-
-
84860545805
-
The role of foxo and ppar transcription factors in diet-mediated inhibition of pdc activation and carbohydrate oxidation during exercise in humans and the role of pharmacological activation of pdc in overriding these changes
-
Constantin-Teodosiu D, Constantin D, Stephens F, Laithwaite D, Greenhaff PL: The role of foxo and ppar transcription factors in diet-mediated inhibition of pdc activation and carbohydrate oxidation during exercise in humans and the role of pharmacological activation of pdc in overriding these changes. Diabetes 2012; 61: 1017-1024.
-
(2012)
Diabetes
, vol.61
, pp. 1017-1024
-
-
Constantin-Teodosiu, D.1
Constantin, D.2
Stephens, F.3
Laithwaite, D.4
Greenhaff, P.L.5
-
41
-
-
0141719702
-
Small molecule activators of sirtuins extend saccharomyces cerevisiae lifespan
-
Howitz KT, Bitterman KJ, Cohen HY, Lamming DW, Lavu S, Wood JG, Zipkin RE, Chung P, Kisielewski A, Zhang LL, Scherer B, Sinclair DA: Small molecule activators of sirtuins extend saccharomyces cerevisiae lifespan. Nature 2003; 425: 191-196.
-
(2003)
Nature
, vol.425
, pp. 191-196
-
-
Howitz, K.T.1
Bitterman, K.J.2
Cohen, H.Y.3
Lamming, D.W.4
Lavu, S.5
Wood, J.G.6
Zipkin, R.E.7
Chung, P.8
Kisielewski, A.9
Zhang, L.L.10
Scherer, B.11
Sinclair, D.A.12
-
42
-
-
33751072349
-
Resveratrol improves health and survival of mice on a high-calorie diet
-
Baur JA, Pearson KJ, Price NL, Jamieson HA, Lerin C, Kalra A, Prabhu VV, Allard JS, Lopez-Lluch G, Lewis K, Pistell PJ, Poosala S, Becker KG, Boss O, Gwinn D, Wang M, Ramaswamy S, Fishbein KW, Spencer RG, Lakatta EG, Le Couteur D, Shaw RJ, Navas P, Puigserver P, Ingram DK, de Cabo R, Sinclair DA: Resveratrol improves health and survival of mice on a high-calorie diet. Nature 2006; 444: 337-342.
-
(2006)
Nature
, vol.444
, pp. 337-342
-
-
Baur, J.A.1
Pearson, K.J.2
Price, N.L.3
Jamieson, H.A.4
Lerin, C.5
Kalra, A.6
Prabhu, V.V.7
Allard, J.S.8
Lopez-Lluch, G.9
Lewis, K.10
Pistell, P.J.11
Poosala, S.12
Becker, K.G.13
Boss, O.14
Gwinn, D.15
Wang, M.16
Ramaswamy, S.17
Fishbein, K.W.18
Spencer, R.G.19
Lakatta, E.G.20
Le Couteur, D.21
Shaw, R.J.22
Navas, P.23
Puigserver, P.24
Ingram, D.K.25
De Cabo, R.26
Sinclair, D.A.27
more..
-
43
-
-
84902330009
-
Modulating effect of sirt1 activation induced by resveratrol on foxo1-associated apoptotic signalling in senescent heart
-
Sin TK, Yu AP, Yung BY, Yip SP, Chan LW, Wong CS, Ying M, Rudd JA, Siu PM: Modulating effect of sirt1 activation induced by resveratrol on foxo1-associated apoptotic signalling in senescent heart. J Physiol 2014; 592: 2535-2548.
-
(2014)
J Physiol
, vol.592
, pp. 2535-2548
-
-
Sin, T.K.1
Yu, A.P.2
Yung, B.Y.3
Yip, S.P.4
Chan, L.W.5
Wong, C.S.6
Ying, M.7
Rudd, J.A.8
Siu, P.M.9
-
44
-
-
84880926594
-
Effects of resveratrol and sirt1 on pgc-1alpha activity and mitochondrial biogenesis: A reevaluation
-
Higashida K, Kim SH, Jung SR, Asaka M, Holloszy JO, Han DH: Effects of resveratrol and sirt1 on pgc-1alpha activity and mitochondrial biogenesis: A reevaluation. PLoS Biol 2013; 11: e1001603.
-
(2013)
PLoS Biol
, vol.11
, pp. e1001603
-
-
Higashida, K.1
Kim, S.H.2
Jung, S.R.3
Asaka, M.4
Holloszy, J.O.5
Han, D.H.6
-
45
-
-
79961092644
-
Long-term supplementation with resveratrol alleviates oxidative stress but does not attenuate sarcopenia in aged mice
-
Jackson JR, Ryan MJ, Alway SE: Long-term supplementation with resveratrol alleviates oxidative stress but does not attenuate sarcopenia in aged mice. J Gerontol A Biol Sci Med Sci 2011; 66: 751-764.
-
(2011)
J Gerontol A Biol Sci Med Sci
, vol.66
, pp. 751-764
-
-
Jackson, J.R.1
Ryan, M.J.2
Alway, S.E.3
-
46
-
-
79955441995
-
Hypoglycemic effect of resveratrol in type 2 diabetic model db/db mice and its actions in cultured l6 myotubes and rin-5f pancreatic beta-cells
-
Minakawa M, Kawano A, Miura Y, Yagasaki K: Hypoglycemic effect of resveratrol in type 2 diabetic model db/db mice and its actions in cultured l6 myotubes and rin-5f pancreatic beta-cells. J Clin Biochem Nutr 2011; 48: 237-244.
-
(2011)
J Clin Biochem Nutr
, vol.48
, pp. 237-244
-
-
Minakawa, M.1
Kawano, A.2
Miura, Y.3
Yagasaki, K.4
-
47
-
-
84899550705
-
Effects of resveratrol in patients with type 2 diabetes mellitus on skeletal muscle sirt1 expression and energy expenditure
-
Goh KP, Lee HY, Lau DP, Supaat W, Chan YH, Koh AF: Effects of resveratrol in patients with type 2 diabetes mellitus on skeletal muscle sirt1 expression and energy expenditure. Int J Sport Nutr Exerc Metab 2014; 24: 2-13.
-
(2014)
Int J Sport Nutr Exerc Metab
, vol.24
, pp. 2-13
-
-
Goh, K.P.1
Lee, H.Y.2
Lau, D.P.3
Supaat, W.4
Chan, Y.H.5
Koh, A.F.6
-
48
-
-
78049356035
-
Insulin and resveratrol act synergistically, preventing cardiac dysfunction in diabetes, but the adVantage of resveratrol in diabetics with acute heart attack is antagonized by insulin
-
Huang JP, Huang SS, Deng JY, Chang CC, Day YJ, Hung LM: Insulin and resveratrol act synergistically, preventing cardiac dysfunction in diabetes, but the adVantage of resveratrol in diabetics with acute heart attack is antagonized by insulin. Free Radic Biol Med 2010; 49: 1710-1721.
-
(2010)
Free Radic Biol Med
, vol.49
, pp. 1710-1721
-
-
Huang, J.P.1
Huang, S.S.2
Deng, J.Y.3
Chang, C.C.4
Day, Y.J.5
Hung, L.M.6
-
49
-
-
84884770604
-
A small volatile bacterial molecule triggers mitochondrial dysfunction in murine skeletal muscle
-
Tzika AA, Constantinou C, Bandyopadhaya A, Psychogios N, Lee S, Mindrinos M, Martyn JA, Tompkins RG, Rahme LG: A small volatile bacterial molecule triggers mitochondrial dysfunction in murine skeletal muscle. PLoS One 2013; 8: e74528.
-
(2013)
PLoS One
, vol.8
, pp. e74528
-
-
Tzika, A.A.1
Constantinou, C.2
Bandyopadhaya, A.3
Psychogios, N.4
Lee, S.5
Mindrinos, M.6
Martyn, J.A.7
Tompkins, R.G.8
Rahme, L.G.9
-
50
-
-
84863062486
-
Suppression of free fatty acid-induced insulin resistance by phytopolyphenols in c2c12 mouse skeletal muscle cells
-
Deng YT, Chang TW, Lee MS, Lin JK: Suppression of free fatty acid-induced insulin resistance by phytopolyphenols in c2c12 mouse skeletal muscle cells. J Agric Food Chem 2012; 60: 1059-1066.
-
(2012)
J Agric Food Chem
, vol.60
, pp. 1059-1066
-
-
Deng, Y.T.1
Chang, T.W.2
Lee, M.S.3
Lin, J.K.4
-
51
-
-
84891685859
-
Myocardial loss of irs1 and irs2 causes heart failure and is controlled by p38alpha mapk during insulin resistance
-
Qi Y, Xu Z, Zhu Q, Thomas C, Kumar R, Feng H, Dostal DE, White MF, Baker KM, Guo S: Myocardial loss of irs1 and irs2 causes heart failure and is controlled by p38alpha mapk during insulin resistance. Diabetes 2013; 62: 3887-3900.
-
(2013)
Diabetes
, vol.62
, pp. 3887-3900
-
-
Qi, Y.1
Xu, Z.2
Zhu, Q.3
Thomas, C.4
Kumar, R.5
Feng, H.6
Dostal, D.E.7
White, M.F.8
Baker, K.M.9
Guo, S.10
-
52
-
-
80052910300
-
Resveratrol improves insulin sensitivity, reduces oxidative stress and activates the akt pathway in type 2 diabetic patients
-
Brasnyo P, Molnar GA, Mohas M, Marko L, Laczy B, Cseh J, Mikolas E, Szijarto IA, Merei A, Halmai R, Meszaros LG, Sumegi B, Wittmann I: Resveratrol improves insulin sensitivity, reduces oxidative stress and activates the akt pathway in type 2 diabetic patients. Br J Nutr 2011; 106: 383-389.
-
(2011)
Br J Nutr
, vol.106
, pp. 383-389
-
-
Brasnyo, P.1
Molnar, G.A.2
Mohas, M.3
Marko, L.4
Laczy, B.5
Cseh, J.6
Mikolas, E.7
Szijarto, I.A.8
Merei, A.9
Halmai, R.10
Meszaros, L.G.11
Sumegi, B.12
Wittmann, I.13
-
53
-
-
79951726016
-
Phosphoinositide 3-kinase as a novel functional target for the regulation of the insulin signaling pathway by sirt1
-
Frojdo S, Durand C, Molin L, Carey AL, El-Osta A, Kingwell BA, Febbraio MA, Solari F, Vidal H, Pirola L: Phosphoinositide 3-kinase as a novel functional target for the regulation of the insulin signaling pathway by sirt1. Mol Cell Endocrinol 2011; 335: 166-176.
-
(2011)
Mol Cell Endocrinol
, vol.335
, pp. 166-176
-
-
Frojdo, S.1
Durand, C.2
Molin, L.3
Carey, A.L.4
El-Osta, A.5
Kingwell, B.A.6
Febbraio, M.A.7
Solari, F.8
Vidal, H.9
Pirola, L.10
-
54
-
-
80555142897
-
Sirt1 enhances skeletal muscle insulin sensitivity in mice during caloric restriction
-
Schenk S, McCurdy CE, Philp A, Chen MZ, Holliday MJ, Bandyopadhyay GK, Osborn O, Baar K, Olefsky JM: Sirt1 enhances skeletal muscle insulin sensitivity in mice during caloric restriction. J Clin Invest 2011; 121: 4281-4288.
-
(2011)
J Clin Invest
, vol.121
, pp. 4281-4288
-
-
Schenk, S.1
McCurdy, C.E.2
Philp, A.3
Chen, M.Z.4
Holliday, M.J.5
Bandyopadhyay, G.K.6
Osborn, O.7
Baar, K.8
Olefsky, J.M.9
-
55
-
-
79960620082
-
The deacetylase sirt1 promotes membrane localization and activation of akt and pdk1 during tumorigenesis and cardiac hypertrophy
-
Sundaresan NR, Pillai VB, Wolfgeher D, Samant S, VasudeVan P, Parekh V, Raghuraman H, Cunningham JM, Gupta M, Gupta MP: The deacetylase sirt1 promotes membrane localization and activation of akt and pdk1 during tumorigenesis and cardiac hypertrophy. Sci Signal 2011; 4: ra46.
-
(2011)
Sci Signal
, vol.4
, pp. ra46
-
-
Sundaresan, N.R.1
Pillai, V.B.2
Wolfgeher, D.3
Samant, S.4
Vasudevan, P.5
Parekh, V.6
Raghuraman, H.7
Cunningham, J.M.8
Gupta, M.9
Gupta, M.P.10
-
56
-
-
79957815888
-
P300 acetyltransferase activity differentially regulates the localization and activity of the foxo homologues in skeletal muscle
-
Senf SM, Sandesara PB, Reed SA, Judge AR: P300 acetyltransferase activity differentially regulates the localization and activity of the foxo homologues in skeletal muscle. Am J Physiol Cell Physiol 2011; 300: C1490-1501.
-
(2011)
Am J Physiol Cell Physiol
, vol.300
, pp. C1490-1501
-
-
Senf, S.M.1
Sandesara, P.B.2
Reed, S.A.3
Judge, A.R.4
-
57
-
-
84855812532
-
Resveratrol prevents dexamethasone-induced expression of the muscle atrophy-related ubiquitin ligases atrogin-1 and murf1 in cultured myotubes through a sirt1-dependent mechanism
-
Alamdari N, Aversa Z, Castillero E, Gurav A, Petkova V, Tizio S, Hasselgren PO: Resveratrol prevents dexamethasone-induced expression of the muscle atrophy-related ubiquitin ligases atrogin-1 and murf1 in cultured myotubes through a sirt1-dependent mechanism. Biochem Biophys Res Commun 2012; 417: 528-533.
-
(2012)
Biochem Biophys Res Commun
, vol.417
, pp. 528-533
-
-
Alamdari, N.1
Aversa, Z.2
Castillero, E.3
Gurav, A.4
Petkova, V.5
Tizio, S.6
Hasselgren, P.O.7
-
58
-
-
84886241944
-
(-)-epicatechin rich cocoa mediated modulation of oxidative stress regulators in skeletal muscle of heart failure and type 2 diabetes patients
-
Ramirez-Sanchez I, Taub PR, Ciaraldi TP, Nogueira L, Coe T, Perkins G, Hogan M, Maisel AS, Henry RR, Ceballos G, Villarreal F: (-)-epicatechin rich cocoa mediated modulation of oxidative stress regulators in skeletal muscle of heart failure and type 2 diabetes patients. Int J Cardiol 2013; 168: 3982-3990.
-
(2013)
Int J Cardiol
, vol.168
, pp. 3982-3990
-
-
Ramirez-Sanchez, I.1
Taub, P.R.2
Ciaraldi, T.P.3
Nogueira, L.4
Coe, T.5
Perkins, G.6
Hogan, M.7
Maisel, A.S.8
Henry, R.R.9
Ceballos, G.10
Villarreal, F.11
-
59
-
-
84898482864
-
Cross talk between angiotensin-(1-7)/mas axis and sirtuins in adipose tissue and metabolism of high-fat feed mice
-
Oliveira Andrade JM, Paraiso AF, Garcia ZM, Ferreira AV, Sinisterra RD, Sousa FB, Guimaraes AL, de Paula AM, Campagnole-Santos MJ, dos Santos RA, Santos SH: Cross talk between angiotensin-(1-7)/mas axis and sirtuins in adipose tissue and metabolism of high-fat feed mice. Peptides 2014; 55: 158-165.
-
(2014)
Peptides
, vol.55
, pp. 158-165
-
-
Oliveira Andrade, J.M.1
Paraiso, A.F.2
Garcia, Z.M.3
Ferreira, A.V.4
Sinisterra, R.D.5
Sousa, F.B.6
Guimaraes, A.L.7
De Paula, A.M.8
Campagnole-Santos, M.J.9
Dos Santos, R.A.10
Santos, S.H.11
-
60
-
-
84860477354
-
Sirt1 is required for ampk activation and the beneficial effects of resveratrol on mitochondrial function
-
Price NL, Gomes AP, Ling AJ, Duarte FV, Martin-Montalvo A, North BJ, Agarwal B, Ye L, Ramadori G, Teodoro JS, Hubbard BP, Varela AT, Davis JG, Varamini B, Hafner A, Moaddel R, Rolo AP, Coppari R, Palmeira CM, de Cabo R, Baur JA, Sinclair DA: Sirt1 is required for ampk activation and the beneficial effects of resveratrol on mitochondrial function. Cell Metab 2012; 15: 675-690.
-
(2012)
Cell Metab
, vol.15
, pp. 675-690
-
-
Price, N.L.1
Gomes, A.P.2
Ling, A.J.3
Duarte, F.V.4
Martin-Montalvo, A.5
North, B.J.6
Agarwal, B.7
Ye, L.8
Ramadori, G.9
Teodoro, J.S.10
Hubbard, B.P.11
Varela, A.T.12
Davis, J.G.13
Varamini, B.14
Hafner, A.15
Moaddel, R.16
Rolo, A.P.17
Coppari, R.18
Palmeira, C.M.19
De Cabo, R.20
Baur, J.A.21
Sinclair, D.A.22
more..
-
61
-
-
84859154631
-
Effects of chronic calorie restriction or dietary resveratrol supplementation on insulin sensitivity markers in a primate, microcebus murinus
-
Marchal J, Blanc S, Epelbaum J, Aujard F, Pifferi F: Effects of chronic calorie restriction or dietary resveratrol supplementation on insulin sensitivity markers in a primate, microcebus murinus. PLoS One 2012; 7: e34289.
-
(2012)
PLoS One
, vol.7
, pp. e34289
-
-
Marchal, J.1
Blanc, S.2
Epelbaum, J.3
Aujard, F.4
Pifferi, F.5
-
62
-
-
84867580794
-
Acute exposure to resveratrol inhibits ampk activity in human skeletal muscle cells
-
Skrobuk P, von Kraemer S, Semenova MM, Zitting A, Koistinen HA: Acute exposure to resveratrol inhibits ampk activity in human skeletal muscle cells. Diabetologia 2012; 55: 3051-3060.
-
(2012)
Diabetologia
, vol.55
, pp. 3051-3060
-
-
Skrobuk, P.1
Von Kraemer, S.2
Semenova, M.M.3
Zitting, A.4
Koistinen, H.A.5
|