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Volumn 62, Issue 12, 2013, Pages 4184-4191

Human insulin resistance is associated with increased plasma levels of 12a-hydroxylated bile acids

Author keywords

[No Author keywords available]

Indexed keywords

12ALPHA HYDROXYLATED BILE ACID; 3 HYDROXYBUTYRIC ACID; ACYLCARNITINE; BILE ACID; BILE ACID CONJUGATE; C PEPTIDE; CHENODEOXYCHOLIC ACID; CHOLIC ACID; DEOXYCHOLIC ACID; GLUCAGON; GLUCOSE; GLUTAMIC ACID; GLYCINE; GLYCOCHENODEOXYCHOLIC ACID; GLYCOCHOLIC ACID; GLYCODEOXYCHOLIC ACID; HEMOGLOBIN A1C; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYODEOXYCHOLIC ACID; INSULIN; LITHOCHOLIC ACID; METFORMIN; PROINSULIN; SULFONYLUREA; TAUROCHENODEOXYCHOLIC ACID; TAUROCHOLIC ACID; TAURODEOXYCHOLIC ACID; TAUROLITHOCHOLIC ACID; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; URSODEOXYCHOLIC ACID;

EID: 84891760775     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db13-0639     Document Type: Article
Times cited : (365)

References (42)
  • 1
    • 58249110568 scopus 로고    scopus 로고
    • Role of bile acids and bile acid receptors in metabolic regulation
    • Lefebvre P, Cariou B, Lien F, Kuipers F, Staels B. Role of bile acids and bile acid receptors in metabolic regulation. Physiol Rev 2009;89: 147-191
    • (2009) Physiol Rev , vol.89 , pp. 147-191
    • Lefebvre, P.1    Cariou, B.2    Lien, F.3    Kuipers, F.4    Staels, B.5
  • 2
    • 34548419344 scopus 로고    scopus 로고
    • Thematic review series: Adipocyte biology. Adipocyte stress: The endoplasmic reticulum and metabolic disease
    • Gregor MF, Hotamisligil GS. Thematic review series: adipocyte biology. Adipocyte stress: the endoplasmic reticulum and metabolic disease. J Lipid Res 2007;48:1905-1914
    • (2007) J Lipid Res , vol.48 , pp. 1905-1914
    • Gregor, M.F.1    Hotamisligil, G.S.2
  • 3
    • 84864861866 scopus 로고    scopus 로고
    • Bile acid receptors as targets for the treatment of dyslipidemia and cardiovascular disease
    • Porez G, Prawitt J, Gross B, Staels B. Bile acid receptors as targets for the treatment of dyslipidemia and cardiovascular disease. J Lipid Res 2012;53: 1723-1737
    • (2012) J Lipid Res , vol.53 , pp. 1723-1737
    • Porez, G.1    Prawitt, J.2    Gross, B.3    Staels, B.4
  • 4
    • 0036725044 scopus 로고    scopus 로고
    • Ursodeoxycholic acid in cholestatic liver disease: Mechanisms of action and therapeutic use revisited
    • Paumgartner G, Beuers U. Ursodeoxycholic acid in cholestatic liver disease: mechanisms of action and therapeutic use revisited. Hepatology 2002;36:525-531
    • (2002) Hepatology , vol.36 , pp. 525-531
    • Paumgartner, G.1    Beuers, U.2
  • 5
    • 0033611305 scopus 로고    scopus 로고
    • The continuing importance of bile acids in liver and intestinal disease
    • Hofmann AF. The continuing importance of bile acids in liver and intestinal disease. Arch Intern Med 1999;159:2647-2658
    • (1999) Arch Intern Med , vol.159 , pp. 2647-2658
    • Hofmann, A.F.1
  • 6
    • 84855850294 scopus 로고    scopus 로고
    • Bile acid sequestrants: More than simple resins
    • Out C, Groen AK, Brufau G. Bile acid sequestrants: more than simple resins. Curr Opin Lipidol 2012;23:43-55
    • (2012) Curr Opin Lipidol , vol.23 , pp. 43-55
    • Out, C.1    Groen, A.K.2    Brufau, G.3
  • 8
    • 69749127975 scopus 로고    scopus 로고
    • Serum bile acids are higher in humans with prior gastric bypass: Potential contribution to improved glucose and lipid metabolism
    • Patti ME, Houten SM, Bianco AC, et al. Serum bile acids are higher in humans with prior gastric bypass: potential contribution to improved glucose and lipid metabolism. Obesity (Silver Spring) 2009;17:1671-1677
    • (2009) Obesity (Silver Spring) , vol.17 , pp. 1671-1677
    • Patti, M.E.1    Houten, S.M.2    Bianco, A.C.3
  • 9
    • 77957002345 scopus 로고    scopus 로고
    • Intestinal adaptation after ileal interposition surgery increases bile acid recycling and protects against obesity-related comorbidities
    • Kohli R, Kirby M, Setchell KD, et al. Intestinal adaptation after ileal interposition surgery increases bile acid recycling and protects against obesity-related comorbidities. Am J Physiol Gastrointest Liver Physiol 2010;299:G652-G660
    • (2010) Am J Physiol Gastrointest Liver Physiol , vol.299
    • Kohli, R.1    Kirby, M.2    Setchell, K.D.3
  • 10
    • 0021739393 scopus 로고
    • Physicochemical properties of bile acids and their relationship to biological properties: An overview of the problem
    • Hofmann AF, Roda A. Physicochemical properties of bile acids and their relationship to biological properties: an overview of the problem. J Lipid Res 1984;25:1477-1489
    • (1984) J Lipid Res , vol.25 , pp. 1477-1489
    • Hofmann, A.F.1    Roda, A.2
  • 12
    • 84855427221 scopus 로고    scopus 로고
    • Impaired generation of 12-hydroxylated bile acids links hepatic insulin signaling with dyslipidemia
    • Haeusler RA, Pratt-Hyatt M, Welch CL, Klaassen CD, Accili D. Impaired generation of 12-hydroxylated bile acids links hepatic insulin signaling with dyslipidemia. Cell Metab 2012;15:65-74
    • (2012) Cell Metab , vol.15 , pp. 65-74
    • Haeusler, R.A.1    Pratt-Hyatt, M.2    Welch, C.L.3    Klaassen, C.D.4    Accili, D.5
  • 14
    • 46749094102 scopus 로고    scopus 로고
    • Hepatic insulin resistance directly promotes formation of cholesterol gallstones
    • Biddinger SB, Haas JT, Yu BB, et al. Hepatic insulin resistance directly promotes formation of cholesterol gallstones. Nat Med 2008;14:778-782
    • (2008) Nat Med , vol.14 , pp. 778-782
    • Biddinger, S.B.1    Haas, J.T.2    Yu, B.B.3
  • 15
    • 0021998704 scopus 로고
    • Altered bile acid metabolism in nonobese, spontaneously diabetic (NOD) mice
    • Uchida K, Makino S, Akiyoshi T. Altered bile acid metabolism in nonobese, spontaneously diabetic (NOD) mice. Diabetes 1985;34:79-83
    • (1985) Diabetes , vol.34 , pp. 79-83
    • Uchida, K.1    Makino, S.2    Akiyoshi, T.3
  • 16
    • 0030325454 scopus 로고    scopus 로고
    • Altered bile acid metabolism related to atherosclerosis in alloxan diabetic rats
    • Uchida K, Satoh T, Takase H, et al. Altered bile acid metabolism related to atherosclerosis in alloxan diabetic rats. J Atheroscler Thromb 1996;3:52-58
    • (1996) J Atheroscler Thromb , vol.3 , pp. 52-58
    • Uchida, K.1    Satoh, T.2    Takase, H.3
  • 17
    • 84862909056 scopus 로고    scopus 로고
    • Glucose and insulin induction of bile acid synthesis: Mechanisms and implication in diabetes and obesity
    • Li T, Francl JM, Boehme S, et al. Glucose and insulin induction of bile acid synthesis: mechanisms and implication in diabetes and obesity. J Biol Chem 2012;287:1861-1873
    • (2012) J Biol Chem , vol.287 , pp. 1861-1873
    • Li, T.1    Francl, J.M.2    Boehme, S.3
  • 18
    • 0041965752 scopus 로고    scopus 로고
    • Feeding natural hydrophilic bile acids inhibits intestinal cholesterol absorption: Studies in the gallstonesusceptible mouse
    • Wang DQ, Tazuma S, Cohen DE, Carey MC. Feeding natural hydrophilic bile acids inhibits intestinal cholesterol absorption: studies in the gallstonesusceptible mouse. Am J Physiol Gastrointest Liver Physiol 2003;285: G494-G502
    • (2003) Am J Physiol Gastrointest Liver Physiol , vol.285
    • Wang, D.Q.1    Tazuma, S.2    Cohen, D.E.3    Carey, M.C.4
  • 19
    • 0033591297 scopus 로고    scopus 로고
    • Identification of a nuclear receptor for bile acids
    • Makishima M, Okamoto AY, Repa JJ, et al. Identification of a nuclear receptor for bile acids. Science 1999;284:1362-1365
    • (1999) Science , vol.284 , pp. 1362-1365
    • Makishima, M.1    Okamoto, A.Y.2    Repa, J.J.3
  • 20
    • 0033591387 scopus 로고    scopus 로고
    • Bile acids: Natural ligands for an orphan nuclear receptor
    • Parks DJ, Blanchard SG, Bledsoe RK, et al. Bile acids: natural ligands for an orphan nuclear receptor. Science 1999;284:1365-1368
    • (1999) Science , vol.284 , pp. 1365-1368
    • Parks, D.J.1    Blanchard, S.G.2    Bledsoe, R.K.3
  • 21
    • 1842844418 scopus 로고    scopus 로고
    • The EGIR-risc study (the european group for the study of insulin resistance: Relationship between insulin sensitivity and cardiovascular disease risk): I. Methodology and objectives
    • Hills SA, Balkau B, Coppack SW, et al.; EGIR-RISC Study Group. The EGIR-RISC Study (the European Group for the Study of Insulin Resistance: Relationship between Insulin Sensitivity and Cardiovascular disease risk): I. Methodology and objectives. Diabetologia 2004;47:566-570
    • (2004) Diabetologia , vol.47 , pp. 566-570
    • Hills, S.A.1    Balkau, B.2    Coppack, S.W.3
  • 22
    • 80052083260 scopus 로고    scopus 로고
    • Body weight, not insulin sensitivity or secretion, may predict spontaneous weight changes in nondiabetic and prediabetic subjects: The RISC study
    • Rebelos E, Muscelli E, Natali A, et al.; RISC Study Investigators. Body weight, not insulin sensitivity or secretion, may predict spontaneous weight changes in nondiabetic and prediabetic subjects: the RISC study. Diabetes 2011;60:1938-1945
    • (2011) Diabetes , vol.60 , pp. 1938-1945
    • Rebelos, E.1    Muscelli, E.2    Natali, A.3
  • 23
    • 0031846461 scopus 로고    scopus 로고
    • How to measure insulin sensitivity
    • Ferrannini E, Mari A. How to measure insulin sensitivity. J Hypertens 1998; 16:895-906
    • (1998) J Hypertens , vol.16 , pp. 895-906
    • Ferrannini, E.1    Mari, A.2
  • 24
    • 82255181866 scopus 로고    scopus 로고
    • Influence of hyperinsulinemia and insulin resistance on in vivo b-cell function: Their role in human b-cell dysfunction
    • Mari A, Tura A, Natali A, et al.; RISC Investigators. Influence of hyperinsulinemia and insulin resistance on in vivo b-cell function: their role in human b-cell dysfunction. Diabetes 2011;60:3141-3147
    • (2011) Diabetes , vol.60 , pp. 3141-3147
    • Mari, A.1    Tura, A.2    Natali, A.3
  • 25
    • 66149119340 scopus 로고    scopus 로고
    • Fatty liver is associated with insulin resistance, risk of coronary heart disease, and early atherosclerosis in a large European population
    • Gastaldelli A, Kozakova M, Højlund K, et al.; RISC Investigators. Fatty liver is associated with insulin resistance, risk of coronary heart disease, and early atherosclerosis in a large European population. Hepatology 2009;49: 1537-1544
    • (2009) Hepatology , vol.49 , pp. 1537-1544
    • Gastaldelli, A.1    Kozakova, M.2    Højlund, K.3
  • 26
    • 84876575039 scopus 로고    scopus 로고
    • Early metabolic markers of the development of dysglycemia and type 2 diabetes and their physiological significance
    • Ferrannini E, Natali A, Camastra S, et al. Early metabolic markers of the development of dysglycemia and type 2 diabetes and their physiological significance. Diabetes 2013;62:1730-1737
    • (2013) Diabetes , vol.62 , pp. 1730-1737
    • Ferrannini, E.1    Natali, A.2    Camastra, S.3
  • 27
    • 0024318186 scopus 로고
    • Quantitative estimation of the hydrophilic-hydrophobic balance of mixed bile salt solutions
    • Heuman DM. Quantitative estimation of the hydrophilic-hydrophobic balance of mixed bile salt solutions. J Lipid Res 1989;30:719-730
    • (1989) J Lipid Res , vol.30 , pp. 719-730
    • Heuman, D.M.1
  • 28
    • 77957960122 scopus 로고    scopus 로고
    • Improved glycemic control with colesevelam treatment in patients with type 2 diabetes is not directly associated with changes in bile acid metabolism
    • Brufau G, Stellaard F, Prado K, et al. Improved glycemic control with colesevelam treatment in patients with type 2 diabetes is not directly associated with changes in bile acid metabolism. Hepatology 2010;52:1455-1464
    • (2010) Hepatology , vol.52 , pp. 1455-1464
    • Brufau, G.1    Stellaard, F.2    Prado, K.3
  • 29
    • 78649735772 scopus 로고    scopus 로고
    • Metabolic footprint of diabetes: A multiplatform metabolomics study in an epidemiological setting
    • Suhre K, Meisinger C, Döring A, et al. Metabolic footprint of diabetes: a multiplatform metabolomics study in an epidemiological setting. PLoS ONE 2010;5:e13953
    • (2010) PLoS ONE , vol.5
    • Suhre, K.1    Meisinger, C.2    Döring, A.3
  • 30
    • 70349430938 scopus 로고    scopus 로고
    • Bile acids: Regulation of synthesis
    • Chiang JY. Bile acids: regulation of synthesis. J Lipid Res 2009;50:1955-1966
    • (2009) J Lipid Res , vol.50 , pp. 1955-1966
    • Chiang, J.Y.1
  • 31
    • 66449085572 scopus 로고    scopus 로고
    • FGF15/FGFR4 integrates growth factor signaling with hepatic bile acid metabolism and insulin action
    • Shin DJ, Osborne TF. FGF15/FGFR4 integrates growth factor signaling with hepatic bile acid metabolism and insulin action. J Biol Chem 2009;284: 11110-11120
    • (2009) J Biol Chem , vol.284 , pp. 11110-11120
    • Shin, D.J.1    Osborne, T.F.2
  • 32
    • 77956244443 scopus 로고    scopus 로고
    • Hepatic FoxO1 ablation exacerbates lipid abnormalities during hyperglycemia
    • Haeusler RA, Han S, Accili D. Hepatic FoxO1 ablation exacerbates lipid abnormalities during hyperglycemia. J Biol Chem 2010;285:26861-26868
    • (2010) J Biol Chem , vol.285 , pp. 26861-26868
    • Haeusler, R.A.1    Han, S.2    Accili, D.3
  • 33
    • 27744518040 scopus 로고    scopus 로고
    • FoxO1 protects against pancreatic beta cell failure through NeuroD and MafA induction
    • Kitamura YI, Kitamura T, Kruse JP, et al. FoxO1 protects against pancreatic beta cell failure through NeuroD and MafA induction. Cell Metab 2005; 2:153-163
    • (2005) Cell Metab , vol.2 , pp. 153-163
    • Kitamura, Y.I.1    Kitamura, T.2    Kruse, J.P.3
  • 35
    • 0018868656 scopus 로고
    • Effects of bile salts on the plasma membranes of isolated rat hepatocytes
    • Billington D, Evans CE, Godfrey PP, Coleman R. Effects of bile salts on the plasma membranes of isolated rat hepatocytes. Biochem J 1980;188: 321-327
    • (1980) Biochem J , vol.188 , pp. 321-327
    • Billington, D.1    Evans, C.E.2    Godfrey, P.P.3    Coleman, R.4
  • 37
    • 20444471137 scopus 로고    scopus 로고
    • Bile acid induces hydrophobicity-dependent membrane alterations
    • Akare S, Martinez JD. Bile acid induces hydrophobicity-dependent membrane alterations. Biochim Biophys Acta 2005;1735:59-67
    • (2005) Biochim Biophys Acta , vol.1735 , pp. 59-67
    • Akare, S.1    Martinez, J.D.2
  • 38
    • 84861880073 scopus 로고    scopus 로고
    • Bile acids acutely stimulate insulin secretion of mouse b-cells via farnesoid X receptor activation and K(ATP) channel inhibition
    • Düfer M, Hörth K, Wagner R, et al. Bile acids acutely stimulate insulin secretion of mouse b-cells via farnesoid X receptor activation and K(ATP) channel inhibition. Diabetes 2012;61:1479-1489
    • (2012) Diabetes , vol.61 , pp. 1479-1489
    • Düfer, M.1    Hörth, K.2    Wagner, R.3
  • 40
    • 1542275425 scopus 로고    scopus 로고
    • The farnesoid X receptor controls gene expression in a ligand-and promoter-selective fashion
    • Lew JL, Zhao A, Yu J, et al. The farnesoid X receptor controls gene expression in a ligand-and promoter-selective fashion. J Biol Chem 2004;279: 8856-8861
    • (2004) J Biol Chem , vol.279 , pp. 8856-8861
    • Lew, J.L.1    Zhao, A.2    Yu, J.3
  • 41
    • 1842527650 scopus 로고    scopus 로고
    • Glucose regulates the expression of the farnesoid X receptor in liver
    • Duran-Sandoval D, Mautino G, Martin G, et al. Glucose regulates the expression of the farnesoid X receptor in liver. Diabetes 2004;53:890-898
    • (2004) Diabetes , vol.53 , pp. 890-898
    • Duran-Sandoval, D.1    Mautino, G.2    Martin, G.3
  • 42
    • 84875851816 scopus 로고    scopus 로고
    • Hepatic glucose sensing is required to preserve b cell glucose competence
    • Seyer P, Vallois D, Poitry-Yamate C, et al. Hepatic glucose sensing is required to preserve b cell glucose competence. J Clin Invest 2013;123:1662-1676
    • (2013) J Clin Invest , vol.123 , pp. 1662-1676
    • Seyer, P.1    Vallois, D.2    Poitry-Yamate, C.3


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