-
1
-
-
10644220306
-
Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity
-
PID: 15565570
-
Browning JD, Szczepaniak LS, Dobbins R, et al. Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity. Hepatology. 2004;40:1387–1395.
-
(2004)
Hepatology
, vol.40
, pp. 1387-1395
-
-
Browning, J.D.1
Szczepaniak, L.S.2
Dobbins, R.3
-
2
-
-
84861591910
-
The diagnosis and management of non-alcoholic fatty liver disease: practice guideline by the American Gastroenterological Association, American Association for the Study of Liver Diseases, and American College of Gastroenterology
-
PID: 22656328
-
Chalasani N, Younossi Z, Lavine JE, et al. The diagnosis and management of non-alcoholic fatty liver disease: practice guideline by the American Gastroenterological Association, American Association for the Study of Liver Diseases, and American College of Gastroenterology. Gastroenterology. 2012;142:1592–1609.
-
(2012)
Gastroenterology
, vol.142
, pp. 1592-1609
-
-
Chalasani, N.1
Younossi, Z.2
Lavine, J.E.3
-
3
-
-
65649124573
-
Bile-acid-induced cell injury and protection
-
COI: 1:CAS:528:DC%2BD1MXpsFCgs7o%3D, PID: 19360911
-
Perez MJ, Briz O. Bile-acid-induced cell injury and protection. World J Gastroenterol. 2009;15:1677–1689.
-
(2009)
World J Gastroenterol
, vol.15
, pp. 1677-1689
-
-
Perez, M.J.1
Briz, O.2
-
4
-
-
84909996208
-
Alcoholic and non-alcoholic steatohepatitis
-
COI: 1:CAS:528:DC%2BC2cXhsFCitrrE, PID: 25217800
-
Neuman MG, French SW, French BA, et al. Alcoholic and non-alcoholic steatohepatitis. Exp Mol Pathol. 2014;97:492–510.
-
(2014)
Exp Mol Pathol
, vol.97
, pp. 492-510
-
-
Neuman, M.G.1
French, S.W.2
French, B.A.3
-
5
-
-
79960081870
-
Profiling circulating and urinary bile acids in patients with biliary obstruction before and after biliary stenting
-
COI: 1:CAS:528:DC%2BC3MXps1Cgs7Y%3D, PID: 21760958
-
Trottier J, Bialek A, Caron P, Straka RJ, Milkiewicz P, Barbier O. Profiling circulating and urinary bile acids in patients with biliary obstruction before and after biliary stenting. PLoS One. 2011;6:e22094.
-
(2011)
PLoS One
, vol.6
, pp. 22094
-
-
Trottier, J.1
Bialek, A.2
Caron, P.3
Straka, R.J.4
Milkiewicz, P.5
Barbier, O.6
-
6
-
-
84879604697
-
Intestinal microbiota in patients with nonalcoholic fatty liver disease
-
COI: 1:CAS:528:DC%2BC3sXhtVaisr%2FN, PID: 23401313
-
Mouzaki M, Comelli EM, Arendt BM, et al. Intestinal microbiota in patients with nonalcoholic fatty liver disease. Hepatology. 2013;58:120–127.
-
(2013)
Hepatology
, vol.58
, pp. 120-127
-
-
Mouzaki, M.1
Comelli, E.M.2
Arendt, B.M.3
-
7
-
-
33244467651
-
Bile salt biotransformations by human intestinal bacteria
-
COI: 1:CAS:528:DC%2BD28XhtlaitL8%3D, PID: 16299351
-
Ridlon JM, Kang DJ, Hylemon PB. Bile salt biotransformations by human intestinal bacteria. J Lipid Res. 2006;47:241–259.
-
(2006)
J Lipid Res
, vol.47
, pp. 241-259
-
-
Ridlon, J.M.1
Kang, D.J.2
Hylemon, P.B.3
-
8
-
-
0033470181
-
Bile acids: the good, the bad, and the ugly
-
COI: 1:CAS:528:DyaK1MXhvVOmt78%3D, PID: 11390813
-
Hofmann AF. Bile acids: the good, the bad, and the ugly. News Physiol Sci. 1999;14:24–29.
-
(1999)
News Physiol Sci
, vol.14
, pp. 24-29
-
-
Hofmann, A.F.1
-
9
-
-
84861198882
-
FXR and PXR: potential therapeutic targets in cholestasis
-
COI: 1:CAS:528:DC%2BC38XntFahurw%3D, PID: 21801835
-
Jonker JW, Liddle C, Downes M. FXR and PXR: potential therapeutic targets in cholestasis. J Steroid Biochem Mol Biol. 2012;130:147–158.
-
(2012)
J Steroid Biochem Mol Biol
, vol.130
, pp. 147-158
-
-
Jonker, J.W.1
Liddle, C.2
Downes, M.3
-
10
-
-
78650325228
-
The relationship between postprandial bile acid concentration, GLP-1, PYY and ghrelin
-
COI: 1:CAS:528:DC%2BC3MXhs1als74%3D
-
Roberts RE, Glicksman C, Alaghband-Zadeh J, Sherwood RA, Akuji N, le Roux CW. The relationship between postprandial bile acid concentration, GLP-1, PYY and ghrelin. Clin Endocrinol. 2011;74:67–72.
-
(2011)
Clin Endocrinol
, vol.74
, pp. 67-72
-
-
Roberts, R.E.1
Glicksman, C.2
Alaghband-Zadeh, J.3
Sherwood, R.A.4
Akuji, N.5
le Roux, C.W.6
-
11
-
-
84880664792
-
Efficacy and safety of the farnesoid X receptor agonist obeticholic acid in patients with type 2 diabetes and nonalcoholic fatty liver disease
-
COI: 1:CAS:528:DC%2BC3sXhtlyrsr3O, PID: 23727264
-
Mudaliar S, Henry RR, Sanyal AJ, et al. Efficacy and safety of the farnesoid X receptor agonist obeticholic acid in patients with type 2 diabetes and nonalcoholic fatty liver disease. Gastroenterology. 2013;145:574–582.
-
(2013)
Gastroenterology
, vol.145
, pp. 574-582
-
-
Mudaliar, S.1
Henry, R.R.2
Sanyal, A.J.3
-
12
-
-
84876146580
-
Free fatty acids repress small heterodimer partner (SHP) activation and adiponectin counteracts bile acid-induced liver injury in superobese patients with nonalcoholic steatohepatitis
-
COI: 1:CAS:528:DC%2BC3sXlslygtrY%3D, PID: 23299969
-
Bechmann LP, Kocabayoglu P, Sowa JP, et al. Free fatty acids repress small heterodimer partner (SHP) activation and adiponectin counteracts bile acid-induced liver injury in superobese patients with nonalcoholic steatohepatitis. Hepatology. 2013;57:1394–1406.
-
(2013)
Hepatology
, vol.57
, pp. 1394-1406
-
-
Bechmann, L.P.1
Kocabayoglu, P.2
Sowa, J.P.3
-
13
-
-
81855206575
-
Variations in ATP-binding cassette transporter regulation during the progression of human nonalcoholic fatty liver disease
-
COI: 1:CAS:528:DC%2BC3MXhsFCru7%2FN, PID: 21878559
-
Hardwick RN, Fisher CD, Canet MJ, Scheffer GL, Cherrington NJ. Variations in ATP-binding cassette transporter regulation during the progression of human nonalcoholic fatty liver disease. Drug Metab Dispos Biol Fate Chem. 2011;39:2395–2402.
-
(2011)
Drug Metab Dispos Biol Fate Chem
, vol.39
, pp. 2395-2402
-
-
Hardwick, R.N.1
Fisher, C.D.2
Canet, M.J.3
Scheffer, G.L.4
Cherrington, N.J.5
-
14
-
-
84929138347
-
Altered morphine glucuronide and bile acid disposition in patients with non-alcoholic steatohepatitis
-
COI: 1:CAS:528:DC%2BC2MXkvFCmtbk%3D, PID: 25669174
-
Ferslew BC, Johnston CK, Tsakalozou E, et al. Altered morphine glucuronide and bile acid disposition in patients with non-alcoholic steatohepatitis. Clin Pharmacol Ther. 2015;97:419–427.
-
(2015)
Clin Pharmacol Ther
, vol.97
, pp. 419-427
-
-
Ferslew, B.C.1
Johnston, C.K.2
Tsakalozou, E.3
-
15
-
-
84881478751
-
Dysregulated bile acid synthesis, metabolism and excretion in a high fat-cholesterol diet-induced fibrotic steatohepatitis in rats
-
COI: 1:CAS:528:DC%2BC3sXht1Gjs77E, PID: 23824403
-
Jia X, Naito H, Yetti H, et al. Dysregulated bile acid synthesis, metabolism and excretion in a high fat-cholesterol diet-induced fibrotic steatohepatitis in rats. Dig Dis Sci. 2013;58:2212–2222.
-
(2013)
Dig Dis Sci
, vol.58
, pp. 2212-2222
-
-
Jia, X.1
Naito, H.2
Yetti, H.3
-
16
-
-
84898824175
-
Interactions between the intestinal microbiome and liver diseases
-
COI: 1:CAS:528:DC%2BC2cXmslWqsLc%3D, PID: 24440671
-
Schnabl B, Brenner DA. Interactions between the intestinal microbiome and liver diseases. Gastroenterology. 2014;146:1513–1524.
-
(2014)
Gastroenterology
, vol.146
, pp. 1513-1524
-
-
Schnabl, B.1
Brenner, D.A.2
-
17
-
-
84901697873
-
Colonic inflammation and secondary bile acids in alcoholic cirrhosis
-
COI: 1:CAS:528:DC%2BC2cXhtFalur7O, PID: 24699327
-
Kakiyama G, Hylemon PB, Zhou H, et al. Colonic inflammation and secondary bile acids in alcoholic cirrhosis. Am J Physiol Gastrointest Liver Physiol. 2014;306:G929–G937.
-
(2014)
Am J Physiol Gastrointest Liver Physiol
, vol.306
, pp. 929-937
-
-
Kakiyama, G.1
Hylemon, P.B.2
Zhou, H.3
-
18
-
-
79951792246
-
Plasma metabolomic profile in nonalcoholic fatty liver disease
-
COI: 1:CAS:528:DC%2BC3MXit1Gru7w%3D, PID: 20423748
-
Kalhan SC, Guo L, Edmison J, et al. Plasma metabolomic profile in nonalcoholic fatty liver disease. Metab Clin Exp. 2011;60:404–413.
-
(2011)
Metab Clin Exp
, vol.60
, pp. 404-413
-
-
Kalhan, S.C.1
Guo, L.2
Edmison, J.3
-
19
-
-
20044374023
-
Design and validation of a histological scoring system for nonalcoholic fatty liver disease
-
PID: 15915461
-
Kleiner DE, Brunt EM, Van Natta M, et al. Design and validation of a histological scoring system for nonalcoholic fatty liver disease. Hepatology. 2005;41:1313–1321.
-
(2005)
Hepatology
, vol.41
, pp. 1313-1321
-
-
Kleiner, D.E.1
Brunt, E.M.2
Van Natta, M.3
-
20
-
-
0026559473
-
Gallbladder emptying stimuli in obese and normal-weight subjects
-
COI: 1:STN:280:DyaK383jsVCmsA%3D%3D, PID: 1568719
-
Stone BG, Ansel HJ, Peterson FJ, Gebhard RL. Gallbladder emptying stimuli in obese and normal-weight subjects. Hepatology. 1992;15:795–798.
-
(1992)
Hepatology
, vol.15
, pp. 795-798
-
-
Stone, B.G.1
Ansel, H.J.2
Peterson, F.J.3
Gebhard, R.L.4
-
21
-
-
84922653598
-
Profiling of serum bile acids in a healthy Chinese population using UPLC-MS/MS
-
COI: 1:CAS:528:DC%2BC2MXmt1Ortg%3D%3D, PID: 25581415
-
Xie G, Wang Y, Wang X, et al. Profiling of serum bile acids in a healthy Chinese population using UPLC-MS/MS. J Proteome Res. 2015;14:850–859.
-
(2015)
J Proteome Res
, vol.14
, pp. 850-859
-
-
Xie, G.1
Wang, Y.2
Wang, X.3
-
22
-
-
84857650587
-
Metabolomic profiling of 17 bile acids in serum from patients with primary biliary cirrhosis and primary sclerosing cholangitis: a pilot study
-
COI: 1:CAS:528:DC%2BC38Xjs1Gqsbw%3D, PID: 22169272
-
Trottier J, Bialek A, Caron P, et al. Metabolomic profiling of 17 bile acids in serum from patients with primary biliary cirrhosis and primary sclerosing cholangitis: a pilot study. Dig Liver Dis. 2012;44:303–310.
-
(2012)
Dig Liver Dis
, vol.44
, pp. 303-310
-
-
Trottier, J.1
Bialek, A.2
Caron, P.3
-
23
-
-
84866183656
-
Targeted profiling of circulating and hepatic bile acids in human, mouse, and rat using a UPLC-MRM-MS-validated method
-
COI: 1:CAS:528:DC%2BC38XhtlOmtLbE, PID: 22822028
-
Garcia-Canaveras JC, Donato MT, Castell JV, Lahoz A. Targeted profiling of circulating and hepatic bile acids in human, mouse, and rat using a UPLC-MRM-MS-validated method. J Lipid Res. 2012;53:2231–2241.
-
(2012)
J Lipid Res
, vol.53
, pp. 2231-2241
-
-
Garcia-Canaveras, J.C.1
Donato, M.T.2
Castell, J.V.3
Lahoz, A.4
-
24
-
-
84863502669
-
Disruption of phospholipid and bile acid homeostasis in mice with nonalcoholic steatohepatitis
-
COI: 1:CAS:528:DC%2BC38XpvVegtbc%3D, PID: 22290395
-
Tanaka N, Matsubara T, Krausz KW, Patterson AD, Gonzalez FJ. Disruption of phospholipid and bile acid homeostasis in mice with nonalcoholic steatohepatitis. Hepatology. 2012;56:118–129.
-
(2012)
Hepatology
, vol.56
, pp. 118-129
-
-
Tanaka, N.1
Matsubara, T.2
Krausz, K.W.3
Patterson, A.D.4
Gonzalez, F.J.5
-
25
-
-
43449094989
-
Bile acid levels are increased in the liver of patients with steatohepatitis
-
COI: 1:CAS:528:DC%2BD1cXlsFOisr0%3D, PID: 18467911
-
Aranha MM, Cortez-Pinto H, Costa A, et al. Bile acid levels are increased in the liver of patients with steatohepatitis. Eur J Gastroenterol Hepatol. 2008;20:519–525.
-
(2008)
Eur J Gastroenterol Hepatol
, vol.20
, pp. 519-525
-
-
Aranha, M.M.1
Cortez-Pinto, H.2
Costa, A.3
-
26
-
-
0037790917
-
The enzymes, regulation, and genetics of bile acid synthesis
-
COI: 1:CAS:528:DC%2BD3sXntFSgtLw%3D, PID: 12543708
-
Russell DW. The enzymes, regulation, and genetics of bile acid synthesis. Annu Rev Biochem. 2003;72:137–174.
-
(2003)
Annu Rev Biochem
, vol.72
, pp. 137-174
-
-
Russell, D.W.1
-
27
-
-
84875066303
-
Decreased hepatotoxic bile acid composition and altered synthesis in progressive human nonalcoholic fatty liver disease
-
COI: 1:CAS:528:DC%2BC3sXktlKks7o%3D, PID: 23391614
-
Lake AD, Novak P, Shipkova P, et al. Decreased hepatotoxic bile acid composition and altered synthesis in progressive human nonalcoholic fatty liver disease. Toxicol Appl Pharmacol. 2013;268:132–140.
-
(2013)
Toxicol Appl Pharmacol
, vol.268
, pp. 132-140
-
-
Lake, A.D.1
Novak, P.2
Shipkova, P.3
-
28
-
-
33644867569
-
Regulation of antibacterial defense in the small intestine by the nuclear bile acid receptor
-
COI: 1:CAS:528:DC%2BD28XivFWitr8%3D, PID: 16473946
-
Inagaki T, Moschetta A, Lee YK, et al. Regulation of antibacterial defense in the small intestine by the nuclear bile acid receptor. Proc Natl Acad Sci USA. 2006;103:3920–3925.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 3920-3925
-
-
Inagaki, T.1
Moschetta, A.2
Lee, Y.K.3
-
29
-
-
69149083245
-
TGR5-mediated bile acid sensing controls glucose homeostasis
-
COI: 1:CAS:528:DC%2BD1MXhsVChtLnM, PID: 19723493
-
Thomas C, Gioiello A, Noriega L, et al. TGR5-mediated bile acid sensing controls glucose homeostasis. Cell Metab. 2009;10:167–177.
-
(2009)
Cell Metab
, vol.10
, pp. 167-177
-
-
Thomas, C.1
Gioiello, A.2
Noriega, L.3
-
30
-
-
31444454037
-
Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation
-
COI: 1:CAS:528:DC%2BD28XntFWmuw%3D%3D, PID: 16400329
-
Watanabe M, Houten SM, Mataki C, et al. Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation. Nature. 2006;439:484–489.
-
(2006)
Nature
, vol.439
, pp. 484-489
-
-
Watanabe, M.1
Houten, S.M.2
Mataki, C.3
-
31
-
-
0032919402
-
Toxic bile salts induce rodent hepatocyte apoptosis via direct activation of Fas
-
COI: 1:CAS:528:DyaK1MXjsl2lsQ%3D%3D, PID: 9884343
-
Faubion WA, Guicciardi ME, Miyoshi H, et al. Toxic bile salts induce rodent hepatocyte apoptosis via direct activation of Fas. J Clin Investig. 1999;103:137–145.
-
(1999)
J Clin Investig
, vol.103
, pp. 137-145
-
-
Faubion, W.A.1
Guicciardi, M.E.2
Miyoshi, H.3
-
32
-
-
0031950282
-
Ursodeoxycholic acid may inhibit deoxycholic acid-induced apoptosis by modulating mitochondrial transmembrane potential and reactive oxygen species production
-
COI: 1:CAS:528:DyaK1cXis1Wksbw%3D, PID: 9562975
-
Rodrigues CM, Fan G, Wong PY, Kren BT, Steer CJ. Ursodeoxycholic acid may inhibit deoxycholic acid-induced apoptosis by modulating mitochondrial transmembrane potential and reactive oxygen species production. Mol Med. 1998;4:165–178.
-
(1998)
Mol Med
, vol.4
, pp. 165-178
-
-
Rodrigues, C.M.1
Fan, G.2
Wong, P.Y.3
Kren, B.T.4
Steer, C.J.5
-
33
-
-
0027227827
-
Glycochenodeoxycholate-induced lethal hepatocellular injury in rat hepatocytes. Role of ATP depletion and cytosolic free calcium
-
COI: 1:CAS:528:DyaK3sXlsFOns7Y%3D, PID: 8325981
-
Spivey JR, Bronk SF, Gores GJ. Glycochenodeoxycholate-induced lethal hepatocellular injury in rat hepatocytes. Role of ATP depletion and cytosolic free calcium. J Clin Investig. 1993;92:17–24.
-
(1993)
J Clin Investig
, vol.92
, pp. 17-24
-
-
Spivey, J.R.1
Bronk, S.F.2
Gores, G.J.3
-
34
-
-
0032525819
-
A novel role for ursodeoxycholic acid in inhibiting apoptosis by modulating mitochondrial membrane perturbation
-
COI: 1:CAS:528:DyaK1cXktVSiu74%3D, PID: 9637713
-
Rodrigues CM, Fan G, Ma X, Kren BT, Steer CJ. A novel role for ursodeoxycholic acid in inhibiting apoptosis by modulating mitochondrial membrane perturbation. J Clin Investig. 1998;101:2790–2799.
-
(1998)
J Clin Investig
, vol.101
, pp. 2790-2799
-
-
Rodrigues, C.M.1
Fan, G.2
Ma, X.3
Kren, B.T.4
Steer, C.J.5
-
35
-
-
11844262660
-
Bile acids as carcinogens in human gastrointestinal cancers
-
COI: 1:CAS:528:DC%2BD2MXis1Wluw%3D%3D, PID: 15652226
-
Bernstein H, Bernstein C, Payne CM, Dvorakova K, Garewal H. Bile acids as carcinogens in human gastrointestinal cancers. Mutat Res. 2005;589:47–65.
-
(2005)
Mutat Res
, vol.589
, pp. 47-65
-
-
Bernstein, H.1
Bernstein, C.2
Payne, C.M.3
Dvorakova, K.4
Garewal, H.5
-
36
-
-
84861197159
-
Hepatocellular carcinoma in non-alcoholic fatty liver disease: an emerging menace
-
PID: 22326465
-
Baffy G, Brunt EM, Caldwell SH. Hepatocellular carcinoma in non-alcoholic fatty liver disease: an emerging menace. J Hepatol. 2012;56:1384–1391.
-
(2012)
J Hepatol
, vol.56
, pp. 1384-1391
-
-
Baffy, G.1
Brunt, E.M.2
Caldwell, S.H.3
-
37
-
-
34948867745
-
Overweight, obesity and risk of liver cancer: a meta-analysis of cohort studies
-
COI: 1:STN:280:DC%2BD2srovFSjsg%3D%3D, PID: 17700568
-
Larsson SC, Wolk A. Overweight, obesity and risk of liver cancer: a meta-analysis of cohort studies. Br J Cancer. 2007;97:1005–1008.
-
(2007)
Br J Cancer
, vol.97
, pp. 1005-1008
-
-
Larsson, S.C.1
Wolk, A.2
-
38
-
-
34247578216
-
Obesity and the risk of gallbladder cancer: a meta-analysis
-
COI: 1:STN:280:DC%2BD2s3mt1Ghsw%3D%3D, PID: 17375043
-
Larsson SC, Wolk A. Obesity and the risk of gallbladder cancer: a meta-analysis. Br J Cancer. 2007;96:1457–1461.
-
(2007)
Br J Cancer
, vol.96
, pp. 1457-1461
-
-
Larsson, S.C.1
Wolk, A.2
-
39
-
-
0017234466
-
Promoting effect of sodium deoxycholate on colon adenocarcinomas in germfree rats
-
COI: 1:STN:280:DyaE287ks1Kqug%3D%3D, PID: 1255778
-
Reddy BS, Narasawa T, Weisburger JH, Wynder EL. Promoting effect of sodium deoxycholate on colon adenocarcinomas in germfree rats. J Natl Cancer Inst. 1976;56:441–442.
-
(1976)
J Natl Cancer Inst
, vol.56
, pp. 441-442
-
-
Reddy, B.S.1
Narasawa, T.2
Weisburger, J.H.3
Wynder, E.L.4
-
40
-
-
79958243702
-
Role of nuclear receptor SHP in metabolism and cancer
-
Zhang Y, Hagedorn CH, Wang L. Role of nuclear receptor SHP in metabolism and cancer. Biochim Biophys Acta. 1812;2011:893–908.
-
(1812)
Biochim Biophys Acta
, vol.2011
, pp. 893-908
-
-
Zhang, Y.1
Hagedorn, C.H.2
Wang, L.3
|