Impaired generation of 12-hydroxylated bile acids links hepatic insulin signaling with dyslipidemia

Cell Metabolism

Volumn 15, Issue 1, 2012, Pages 65-74

  Haeusler, Rebecca A ^a   Pratt Hyatt, Matthew ^b   Welch, Carrie L ^a   Klaassen, Curtis D ^b   Accili, Domenico ^a  

^a Howard Hughes Medical Institute   (United States)

^b UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

12 HYDROXYLATED BILE ACID DERIVATIVE; BILE ACID; CHOLESTEROL; CYTOCHROME P450; CYTOCHROME P450 8B1; GLUCOSE; INSULIN; LIPID; TRANSCRIPTION FACTOR FKHR; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILE ACID METABOLISM; CHOLESTEROL SYNTHESIS; CONTROLLED STUDY; DIABETES MELLITUS; DIET; DYSLIPIDEMIA; GENE EXPRESSION; HOMEOSTASIS; MALE; METABOLIC SYNDROME X; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; BILE ACIDS AND SALTS; DIABETES MELLITUS, TYPE 2; DYSLIPIDEMIAS; FORKHEAD TRANSCRIPTION FACTORS; GLUCOSE; HYDROXYLATION; INSULIN; ISOXAZOLES; LIPID METABOLISM; LIVER; MALE; METABOLOME; MICE; MICE, KNOCKOUT; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SIGNAL TRANSDUCTION; STEROID 12-ALPHA-HYDROXYLASE; TRIGLYCERIDES;

MUS;

EID: 84855427221     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2011.11.010     Document Type: Article

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