-
1
-
-
77952016461
-
Continuous plug flow crystallization of pharmaceutical compounds
-
Alvarez AJ, Myerson AS. 2010. Continuous plug flow crystallization of pharmaceutical compounds. Cryst Growth Des 10:2219-2228.
-
(2010)
Cryst Growth Des
, vol.10
, pp. 2219-2228
-
-
Alvarez, A.J.1
Myerson, A.S.2
-
2
-
-
84930377472
-
Twin-column CaptureSMB: A novel cyclic process for protein A affinity chromatography
-
Angarita M, Müller-Späth T, Baur D, Lievrouw R, Lissens G, Morbidelli M. 2015. Twin-column CaptureSMB: A novel cyclic process for protein A affinity chromatography, J Chromatogr A 1389:85-95.
-
(2015)
J Chromatogr A
, vol.1389
, pp. 85-95
-
-
Angarita, M.1
Müller-Späth, T.2
Baur, D.3
Lievrouw, R.4
Lissens, G.5
Morbidelli, M.6
-
3
-
-
84907449797
-
Simulated moving bed strategies and designs: From established systems to the latest developments
-
Aniceto JPS, Silva CM. 2015. Simulated moving bed strategies and designs: From established systems to the latest developments. Sep Purif Rev 44:41-73.
-
(2015)
Sep Purif Rev
, vol.44
, pp. 41-73
-
-
Aniceto, J.P.S.1
Silva, C.M.2
-
4
-
-
0022730202
-
Large-scale cell culture in biotechnology
-
Arathoon WR, Birch JR. 1986. Large-scale cell culture in biotechnology. Science 232:1390-1395.
-
(1986)
Science
, vol.232
, pp. 1390-1395
-
-
Arathoon, W.R.1
Birch, J.R.2
-
5
-
-
36749023476
-
A continuous multicolumn countercurrent solvent gradient purification (MCSGP) process
-
Aumann L, Morbidelli M. 2007. A continuous multicolumn countercurrent solvent gradient purification (MCSGP) process. Biotechnol Bioeng 98:1043-1055.
-
(2007)
Biotechnol Bioeng
, vol.98
, pp. 1043-1055
-
-
Aumann, L.1
Morbidelli, M.2
-
6
-
-
84867397163
-
Quality by design: Impact of formulation variables and their interactions on quality attributes of a lyophilized monoclonal antibody
-
Awotwe-Otoo D, Agarabi C, Wu GK, Casey E, Read E, Lute S, Brorson KA, Khan MA, Shah RB. 2012. Quality by design: Impact of formulation variables and their interactions on quality attributes of a lyophilized monoclonal antibody. Int J Pharmaceutics 438:167-175.
-
(2012)
Int J Pharmaceutics
, vol.438
, pp. 167-175
-
-
Awotwe-Otoo, D.1
Agarabi, C.2
Wu, G.K.3
Casey, E.4
Read, E.5
Lute, S.6
Brorson, K.A.7
Khan, M.A.8
Shah, R.B.9
-
7
-
-
75649109719
-
Evaluation of viral inactivation efficacy of a continuous flow ultraviolet-C reactor (UVivatec)
-
Bae JE, Jeong EK, Lee JI, Lee JI, Kim IS, Kum J-S. 2009. Evaluation of viral inactivation efficacy of a continuous flow ultraviolet-C reactor (UVivatec). Kor J Microbiol Biotechnol 4:377-382.
-
(2009)
Kor J Microbiol Biotechnol
, vol.4
, pp. 377-382
-
-
Bae, J.E.1
Jeong, E.K.2
Lee, J.I.3
Lee, J.I.4
Kim, I.S.5
Kum, J.-S.6
-
9
-
-
0035125231
-
Continuous removal of protein aggregates by annular chromatography
-
Buchacher A, Iberer G, Jungbauer A, Schwinn H, Josic D. 2001. Continuous removal of protein aggregates by annular chromatography. Biotechnol Prog 17:140-149.
-
(2001)
Biotechnol Prog
, vol.17
, pp. 140-149
-
-
Buchacher, A.1
Iberer, G.2
Jungbauer, A.3
Schwinn, H.4
Josic, D.5
-
10
-
-
33846117881
-
Evaluation of radial chromatography versus axial chromatography, practical approach
-
Cabanne C, Raedts M, Zavadzky E, Santarelli X. 2007. Evaluation of radial chromatography versus axial chromatography, practical approach. J Chromatogr B, 845:191-199
-
(2007)
J Chromatogr B
, vol.845
, pp. 191-199
-
-
Cabanne, C.1
Raedts, M.2
Zavadzky, E.3
Santarelli, X.4
-
11
-
-
84856522368
-
In situ product recovery: Submerged membranes vs. external loop membranes
-
Carstensen F, Apel A, Wessling M. 2012. In situ product recovery: Submerged membranes vs. external loop membranes. J Membrane Sci 394:1-36.
-
(2012)
J Membrane Sci
, vol.394
, pp. 1-36
-
-
Carstensen, F.1
Apel, A.2
Wessling, M.3
-
12
-
-
80054831290
-
Protein concentration with single-pass tangential flow filtration (SPTFF)
-
Casey C, Gallos T, Alekseev Y, Ayturk E, Pearl S. 2011. Protein concentration with single-pass tangential flow filtration (SPTFF). J Membrane Sci 384:82-88.
-
(2011)
J Membrane Sci
, vol.384
, pp. 82-88
-
-
Casey, C.1
Gallos, T.2
Alekseev, Y.3
Ayturk, E.4
Pearl, S.5
-
13
-
-
84879258603
-
Very high density of Chinese hamster ovary cells in perfusion by ATF or TFF in WAVE bioreactor™. Part I: Effect of the cell density on the process
-
Clincke M-F., Mölleryd C, Zhang Y, Lindskog E, Walsh K, Chotteau V. 2013. Very high density of Chinese hamster ovary cells in perfusion by ATF or TFF in WAVE bioreactor™. Part I: Effect of the cell density on the process. Biotechnol Prog 29:754-767.
-
(2013)
Biotechnol Prog
, vol.29
, pp. 754-767
-
-
Clincke, M.-F.1
Mölleryd, C.2
Zhang, Y.3
Lindskog, E.4
Walsh, K.5
Chotteau, V.6
-
14
-
-
0030019157
-
Practical considerations in operation and scale-up of spin-filter based bioreactors for monoclonal antibody production
-
Deo YM, Mahadevan MD, Fuchs R. 1996. Practical considerations in operation and scale-up of spin-filter based bioreactors for monoclonal antibody production. Biotechnol Prog 12:57-64.
-
(1996)
Biotechnol Prog
, vol.12
, pp. 57-64
-
-
Deo, Y.M.1
Mahadevan, M.D.2
Fuchs, R.3
-
15
-
-
84857442266
-
Single pass tangential flow filtration to debottleneck downstream processing for therapeutic antibody production
-
Dizon-Maspat J, Bourret J, D'Agostini A, Li F. 2012. Single pass tangential flow filtration to debottleneck downstream processing for therapeutic antibody production. Biotechnol Bioeng 109:962-970.
-
(2012)
Biotechnol Bioeng
, vol.109
, pp. 962-970
-
-
Dizon-Maspat, J.1
Bourret, J.2
D'Agostini, A.3
Li, F.4
-
16
-
-
84930218144
-
Purification of monoclonal antibodies from clarified cell culture fluid using protein A capture continuous countercurrent tangential chromatography
-
Dutta AK, Tran T, Napadensky B, Teella A, Brookhart G, Ropp PA, Zhang AW, Tustian AD, Zydney AL, Shinkazh O. 2015. Purification of monoclonal antibodies from clarified cell culture fluid using protein A capture continuous countercurrent tangential chromatography. J Biotechnol. doi: 10.1016/j.jbiotec.2015.02.026.
-
(2015)
J Biotechnol
-
-
Dutta, A.K.1
Tran, T.2
Napadensky, B.3
Teella, A.4
Brookhart, G.5
Ropp, P.A.6
Zhang, A.W.7
Tustian, A.D.8
Zydney, A.L.9
Shinkazh, O.10
-
17
-
-
84897021272
-
Multi-stage aqueous two-phase extraction for the purification of monoclonal antibodies
-
Eggersgluess JK, Richter M, Dieterle M, Strube J. 2014. Multi-stage aqueous two-phase extraction for the purification of monoclonal antibodies. Chem Eng Tech 37:675-682.
-
(2014)
Chem Eng Tech
, vol.37
, pp. 675-682
-
-
Eggersgluess, J.K.1
Richter, M.2
Dieterle, M.3
Strube, J.4
-
19
-
-
61449212077
-
Viral clearance using monoliths
-
Etzel MR, Riordan WT. 2009. Viral clearance using monoliths. J Chromatog A 1216:2621-2624.
-
(2009)
J Chromatog A
, vol.1216
, pp. 2621-2624
-
-
Etzel, M.R.1
Riordan, W.T.2
-
20
-
-
84920134514
-
A membrane stirrer for product recovery and substrate feeding
-
Femmer T, Carstensen F, Wessling M. 2015. A membrane stirrer for product recovery and substrate feeding. Biotechnol Bioeng 112:331-338.
-
(2015)
Biotechnol Bioeng
, vol.112
, pp. 331-338
-
-
Femmer, T.1
Carstensen, F.2
Wessling, M.3
-
21
-
-
73449090754
-
CFD simulation of an internal spin-filter: Evidence of lateral migration and exchange flow through the mesh
-
Figueredo-Cardero A, Chico E, Castilho LR, Medronho RA. 2009. CFD simulation of an internal spin-filter: Evidence of lateral migration and exchange flow through the mesh. Cytotechnology 61:55-64.
-
(2009)
Cytotechnology
, vol.61
, pp. 55-64
-
-
Figueredo-Cardero, A.1
Chico, E.2
Castilho, L.R.3
Medronho, R.A.4
-
22
-
-
84874199746
-
Zonal rate model for axial and radial flow membrane chromatography. Part I: Knowledge transfer across operating conditions and scales
-
Ghosh P, Vahedipour K, Lin M, Vogel JH, Haynes CA, von Lieres E. 2013. Zonal rate model for axial and radial flow membrane chromatography. Part I: Knowledge transfer across operating conditions and scales. Biotechnol Bioeng 110:1129-1141.
-
(2013)
Biotechnol Bioeng
, vol.110
, pp. 1129-1141
-
-
Ghosh, P.1
Vahedipour, K.2
Lin, M.3
Vogel, J.H.4
Haynes, C.A.5
von Lieres, E.6
-
23
-
-
84864052659
-
Cation exchange surface-mediated denaturation of an aglycosylated immunoglobulin (IgG1)
-
Gillespie R, Nguyen T, Macneil S, Jones L, Crampton S, Vunnum S. 2012. Cation exchange surface-mediated denaturation of an aglycosylated immunoglobulin (IgG1). J Chromatog A 1251:101-110.
-
(2012)
J Chromatog A
, vol.1251
, pp. 101-110
-
-
Gillespie, R.1
Nguyen, T.2
Macneil, S.3
Jones, L.4
Crampton, S.5
Vunnum, S.6
-
24
-
-
84870662932
-
Periodic counter-current chromatography - design and operational considerations for integrated and continuous purification of proteins
-
Godawat R, Brower K, Jain S, Konstantinov K, Riske F, Warikoo V. 2012. Periodic counter-current chromatography - design and operational considerations for integrated and continuous purification of proteins. Biotechnol J 12:1496-1508.
-
(2012)
Biotechnol J
, vol.12
, pp. 1496-1508
-
-
Godawat, R.1
Brower, K.2
Jain, S.3
Konstantinov, K.4
Riske, F.5
Warikoo, V.6
-
26
-
-
84904277925
-
Unfolding of a model protein on ion exchange and mixed mode chromatography surfaces
-
Gospodarek AM, Hiser DE, O'Connell JP, Fernandez EJ. 2014. Unfolding of a model protein on ion exchange and mixed mode chromatography surfaces. J Chromatog A 1355:238-252.
-
(2014)
J Chromatog A
, vol.1355
, pp. 238-252
-
-
Gospodarek, A.M.1
Hiser, D.E.2
O'Connell, J.P.3
Fernandez, E.J.4
-
27
-
-
84907276157
-
Unfolding and aggregation of a glycosylated monoclonal antibody on a cation exchange column. Part II. Protein structure effects by hydrogen deuterium exchange mass spectrometry
-
Guo J, Carta G. 2014. Unfolding and aggregation of a glycosylated monoclonal antibody on a cation exchange column. Part II. Protein structure effects by hydrogen deuterium exchange mass spectrometry. J Chromatog A 1356:129-137.
-
(2014)
J Chromatog A
, vol.1356
, pp. 129-137
-
-
Guo, J.1
Carta, G.2
-
28
-
-
84901696090
-
Economics of recombinant antibody production processes at various scales: Industry-standard compared to continuous precipitation
-
Hammerschmidt N, Tscheliessnig A, Sommer R, Helk B, Jungbauer A. 2014. Economics of recombinant antibody production processes at various scales: Industry-standard compared to continuous precipitation. Biotechnol J 9:766-775.
-
(2014)
Biotechnol J
, vol.9
, pp. 766-775
-
-
Hammerschmidt, N.1
Tscheliessnig, A.2
Sommer, R.3
Helk, B.4
Jungbauer, A.5
-
29
-
-
0014661176
-
Spin-filter culture: The propagation of mammalian cells in suspension
-
Himmelfarb P, Thayer PS, Martin HE. 1969. Spin-filter culture: The propagation of mammalian cells in suspension. Science 164:555-557.
-
(1969)
Science
, vol.164
, pp. 555-557
-
-
Himmelfarb, P.1
Thayer, P.S.2
Martin, H.E.3
-
30
-
-
84925154997
-
Preparative crystallization of a single chain antibody using an aqueous two-phase system
-
Huettmann H, Berkemeyer M, Buchinger W, Jungbauer A. 2014. Preparative crystallization of a single chain antibody using an aqueous two-phase system. Biotechnol Bioeng 111:2192-2199.
-
(2014)
Biotechnol Bioeng
, vol.111
, pp. 2192-2199
-
-
Huettmann, H.1
Berkemeyer, M.2
Buchinger, W.3
Jungbauer, A.4
-
32
-
-
84906821537
-
Avoiding antibody aggregation during processing: Establishing hold times
-
Joshi V, Shivach T, Kumar V, Yadav N, Rathore A. 2014. Avoiding antibody aggregation during processing: Establishing hold times. Biotechnol J 9:1195-1205.
-
(2014)
Biotechnol J
, vol.9
, pp. 1195-1205
-
-
Joshi, V.1
Shivach, T.2
Kumar, V.3
Yadav, N.4
Rathore, A.5
-
33
-
-
84880510340
-
Continuous downstream processing of biopharmaceuticals
-
Jungbauer A. 2013. Continuous downstream processing of biopharmaceuticals. Trends Biotechnol 31:479-492.
-
(2013)
Trends Biotechnol
, vol.31
, pp. 479-492
-
-
Jungbauer, A.1
-
34
-
-
77953655955
-
Industrialization of mAb production technology: The bioprocessing industry at a crossroads
-
Kelley B. 2009. Industrialization of mAb production technology: The bioprocessing industry at a crossroads. mAbs 1:443-452.
-
(2009)
mAbs
, vol.1
, pp. 443-452
-
-
Kelley, B.1
-
35
-
-
84914701270
-
Understanding and modeling alternating tangential flow filtration for perfusion cell culture
-
Kelly W, Scully J, Zhang D, Feng G, Lavengood M, Condon J, Knighton J, Bhatia R. 2014. Understanding and modeling alternating tangential flow filtration for perfusion cell culture. Biotechnol Prog 30:1291-1300.
-
(2014)
Biotechnol Prog
, vol.30
, pp. 1291-1300
-
-
Kelly, W.1
Scully, J.2
Zhang, D.3
Feng, G.4
Lavengood, M.5
Condon, J.6
Knighton, J.7
Bhatia, R.8
-
37
-
-
33749260301
-
The "push-to-low" approach for optimization of high-density perfusion cultures of animal cells
-
Konstantinov K, Goudar C, Ng M, Meneses R, Thrift J, Chuppa S, Matanguihan C, Micheals J, Naveh D. 2006. The "push-to-low" approach for optimization of high-density perfusion cultures of animal cells. Adv Biochem Eng Biotechnol 101: 75-98.
-
(2006)
Adv Biochem Eng Biotechnol
, vol.101
, Issue.75
-
-
Konstantinov, K.1
Goudar, C.2
Ng, M.3
Meneses, R.4
Thrift, J.5
Chuppa, S.6
Matanguihan, C.7
Micheals, J.8
Naveh, D.9
-
38
-
-
84877597391
-
Online control of the twin-column countercurrent solvent gradient process for biochromatography
-
Krättli M, Steinebach F, Morbidelli M. 2013. Online control of the twin-column countercurrent solvent gradient process for biochromatography, J Chromatogr A 1293:51-59.
-
(2013)
J Chromatogr A
, vol.1293
, pp. 51-59
-
-
Krättli, M.1
Steinebach, F.2
Morbidelli, M.3
-
39
-
-
84891121113
-
Modeling and control of crystal shape in continuous protein crystallization
-
Kwon JS-I, Nayhouse M, Christofides PD, Orkoulas G. 2014. Modeling and control of crystal shape in continuous protein crystallization. Chem Eng Sci 107:47-57.
-
(2014)
Chem Eng Sci
, vol.107
, pp. 47-57
-
-
Kwon, J.-I.1
Nayhouse, M.2
Christofides, P.D.3
Orkoulas, G.4
-
40
-
-
35948998871
-
Continuous processes for the production of pharmaceutical intermediates and active pharmaceutical ingredients
-
LaPorte TL, Wang C. 2007. Continuous processes for the production of pharmaceutical intermediates and active pharmaceutical ingredients. Curr Opinion Drug Disc Develop 10:738-745.
-
(2007)
Curr Opinion Drug Disc Develop
, vol.10
, pp. 738-745
-
-
LaPorte, T.L.1
Wang, C.2
-
42
-
-
48449091706
-
Application of high-performance tangential flow filtration (HPTFF) to the purification of a human pharmaceutical antibody fragment expressed in Escherichia coli
-
Lebreton B, Brown A, van Reis A. 2008. Application of high-performance tangential flow filtration (HPTFF) to the purification of a human pharmaceutical antibody fragment expressed in Escherichia coli. Biotechnol Bioeng 100:964-974.
-
(2008)
Biotechnol Bioeng
, vol.100
, pp. 964-974
-
-
Lebreton, B.1
Brown, A.2
van Reis, A.3
-
43
-
-
20444370296
-
Design of a UV-C irradiation process for the inactivation of viruses in protein solutions
-
Li Q, Macdonald S, Bienek C, Foster PR, Macleod AJ. 2005. Design of a UV-C irradiation process for the inactivation of viruses in protein solutions. Biologicals 33:101-100.
-
(2005)
Biologicals
, vol.33
, pp. 100-101
-
-
Li, Q.1
Macdonald, S.2
Bienek, C.3
Foster, P.R.4
Macleod, A.J.5
-
44
-
-
84863298500
-
Recent advances in membrane bioreactors: Configuration development, pollutant elimination, and sludge reduction
-
Meng FG, Chae SR, Shin HS, Yang FL, Zhou ZB. 2012. Recent advances in membrane bioreactors: Configuration development, pollutant elimination, and sludge reduction. Env Engineering Sci 29:139-160.
-
(2012)
Env Engineering Sci
, vol.29
, pp. 139-160
-
-
Meng, F.G.1
Chae, S.R.2
Shin, H.S.3
Yang, F.L.4
Zhou, Z.B.5
-
45
-
-
77953045118
-
Analysis of viral clearance unit operations for monoclonal antibodies
-
Miesegaes G, Lute S, Brorson K. 2010. Analysis of viral clearance unit operations for monoclonal antibodies. Biotechnol Bioeng 106:238-246.
-
(2010)
Biotechnol Bioeng
, vol.106
, pp. 238-246
-
-
Miesegaes, G.1
Lute, S.2
Brorson, K.3
-
46
-
-
78149348184
-
Two step capture and purification of IgG(2) using a multicolumn solvent gradient purification (MCSGP)
-
Muller-Spath T, Aumann L, Strohlein G, Kommann H, Valax P, Delegrange L, Charbaut E, Baer G, Lamproye A, Johnck M, Schulte M, Morbidelli M. 2010a. Two step capture and purification of IgG(2) using a multicolumn solvent gradient purification (MCSGP). Biotechnol Bioeng 107:974-984.
-
(2010)
Biotechnol Bioeng
, vol.107
, pp. 974-984
-
-
Muller-Spath, T.1
Aumann, L.2
Strohlein, G.3
Kommann, H.4
Valax, P.5
Delegrange, L.6
Charbaut, E.7
Baer, G.8
Lamproye, A.9
Johnck, M.10
Schulte, M.11
Morbidelli, M.12
-
47
-
-
48649086491
-
Chromatographic separation of three monoclonal antibody variants using multicolumn countercurrent solvent gradient purification (MCSGP)
-
Muller-Spath T, Aumann L, Melter L, Ströhlein G, Morbidelli M. 2008. Chromatographic separation of three monoclonal antibody variants using multicolumn countercurrent solvent gradient purification (MCSGP). Biotechnol Bioeng 100:1166-1177.
-
(2008)
Biotechnol Bioeng
, vol.100
, pp. 1166-1177
-
-
Muller-Spath, T.1
Aumann, L.2
Melter, L.3
Ströhlein, G.4
Morbidelli, M.5
-
48
-
-
78149341322
-
Increasing the activity of monoclonal antibody therapeutics by continuous chromatography (MCSGP)
-
Muller-Spath T, Krattli M, Aumann L, Strohlein G, Morbidelli M. 2010b. Increasing the activity of monoclonal antibody therapeutics by continuous chromatography (MCSGP). Biotechnol Bioeng 107:652-662.
-
(2010)
Biotechnol Bioeng
, vol.107
, pp. 652-662
-
-
Muller-Spath, T.1
Krattli, M.2
Aumann, L.3
Strohlein, G.4
Morbidelli, M.5
-
49
-
-
84877250732
-
Continuous countercurrent tangential chromatography for monoclonal antibody purification
-
Napadensky B, Shinkazh O, Teella A, Zydney A. 2013. Continuous countercurrent tangential chromatography for monoclonal antibody purification. Sep Sci Technol 48:1289-1297.
-
(2013)
Sep Sci Technol
, vol.48
, pp. 1289-1297
-
-
Napadensky, B.1
Shinkazh, O.2
Teella, A.3
Zydney, A.4
-
50
-
-
84902667407
-
Equipment for large-scale mammalian cell culture
-
Ozturk SS. 2014. Equipment for large-scale mammalian cell culture. Adv Biochem Engng-Biotech 139:69-92.
-
(2014)
Adv Biochem Engng-Biotech
, vol.139
, pp. 69-92
-
-
Ozturk, S.S.1
-
51
-
-
80051798475
-
Effects of cell culture conditions on antibody N-linked glycosylation - What affects high mannose 5 glycoform
-
Pacis E, Yu M, Autsen J, Bayer R, Li F. 2011. Effects of cell culture conditions on antibody N-linked glycosylation - What affects high mannose 5 glycoform. Biotechnol Bioeng 108:2348-2358.
-
(2011)
Biotechnol Bioeng
, vol.108
, pp. 2348-2358
-
-
Pacis, E.1
Yu, M.2
Autsen, J.3
Bayer, R.4
Li, F.5
-
52
-
-
84890329089
-
Potential impact of membrane cascading on downstream processing of oligosaccharides
-
Patil NV, Janssen AEM, Boom RM. 2014. Potential impact of membrane cascading on downstream processing of oligosaccharides. Chem Eng Sci 106:86-98.
-
(2014)
Chem Eng Sci
, vol.106
, pp. 86-98
-
-
Patil, N.V.1
Janssen, A.E.M.2
Boom, R.M.3
-
53
-
-
84901327047
-
Continuous purification of active pharmaceutical ingredients using multistage organic solvent nanofiltration membrane cascade
-
Peeva L, da Silva Burgal J, Valtcheva I, Livingston AG. 2014. Continuous purification of active pharmaceutical ingredients using multistage organic solvent nanofiltration membrane cascade. Chem Eng Sci 116:183-194.
-
(2014)
Chem Eng Sci
, vol.116
, pp. 183-194
-
-
Peeva, L.1
da Silva Burgal, J.2
Valtcheva, I.3
Livingston, A.G.4
-
54
-
-
58149107461
-
Simulated moving bed chromatography for the separation of enantiomers
-
Rajendran A, Paredes G, Mazzotti M. 2009. Simulated moving bed chromatography for the separation of enantiomers. J Chromatog A 1216:709-738.
-
(2009)
J Chromatog A
, vol.1216
, pp. 709-738
-
-
Rajendran, A.1
Paredes, G.2
Mazzotti, M.3
-
55
-
-
84941071281
-
Continuous processing for production of biopharmaceuticals
-
Rathore AS, Agarwal H, Sharma AK, Pathak M, Muthukumar S. 2015. Continuous processing for production of biopharmaceuticals. Prep Biochem Biotechnol 45:836-849.
-
(2015)
Prep Biochem Biotechnol
, vol.45
, pp. 836-849
-
-
Rathore, A.S.1
Agarwal, H.2
Sharma, A.K.3
Pathak, M.4
Muthukumar, S.5
-
56
-
-
85052574511
-
Glimpses into the realm of freeze-drying: Classical issues and new ventures
-
In: Rey L, May JC, editors. . London: Informa Healthcare.
-
Rey I. 2010. Glimpses into the realm of freeze-drying: Classical issues and new ventures. In: Rey L, May JC, editors. Freeze drying/lyophilization of pharmaceutical and biological products. London: Informa Healthcare. p 1-28.
-
(2010)
Freeze drying/lyophilization of pharmaceutical and biological products
, pp. 1-28
-
-
Rey, I.1
-
57
-
-
79952608234
-
Purification of singly-pegylated alpha-lactalbumin using charged ultrafiltration membranes
-
Ruanjaikaen K, Zydney AL. 2011. Purification of singly-pegylated alpha-lactalbumin using charged ultrafiltration membranes. Biotechnol Bioeng 108:822-829.
-
(2011)
Biotechnol Bioeng
, vol.108
, pp. 822-829
-
-
Ruanjaikaen, K.1
Zydney, A.L.2
-
58
-
-
78751525301
-
Countercurrent tangential chromatography for large-scale protein purification
-
Shinkazh O, Kanani D, Barth M, Long M, Hussain D, Zydney AL. 2011. Countercurrent tangential chromatography for large-scale protein purification. Biotechnol Bioeng 108:582-591.
-
(2011)
Biotechnol Bioeng
, vol.108
, pp. 582-591
-
-
Shinkazh, O.1
Kanani, D.2
Barth, M.3
Long, M.4
Hussain, D.5
Zydney, A.L.6
-
59
-
-
79955877697
-
Challenges in the development of high protein concentration formulations
-
In: Shire SJ, Gombotz W, Bechtold Peters J, and Ya J, editors. . New York: Springer.
-
Shire SJ, Shahrokh Z, Liu J. 2010. Challenges in the development of high protein concentration formulations. In: Shire SJ, Gombotz W, Bechtold Peters J, and Ya J, editors. Current trends in monclonal antibody development and manufacturing. New York: Springer. p 131-147.
-
(2010)
Current trends in monclonal antibody development and manufacturing
, pp. 131-147
-
-
Shire, S.J.1
Shahrokh, Z.2
Liu, J.3
-
60
-
-
8144221045
-
Acoustic cell filter: A proven cell retention technology for perfusion of animal cell cultures
-
Shirgaonkar IZ, Lanthier S, Kamen A. 2004. Acoustic cell filter: A proven cell retention technology for perfusion of animal cell cultures. Biotechnol Adv 22:433-444.
-
(2004)
Biotechnol Adv
, vol.22
, pp. 433-444
-
-
Shirgaonkar, I.Z.1
Lanthier, S.2
Kamen, A.3
-
63
-
-
0036273097
-
Preparative continuous annular chromatography (P-CAC), a review
-
Uretschlager A, Jungbauer A. 2002. Preparative continuous annular chromatography (P-CAC), a review. Bioprocess Biosyst Eng 25:129-140.
-
(2002)
Bioprocess Biosyst Eng
, vol.25
, pp. 129-140
-
-
Uretschlager, A.1
Jungbauer, A.2
-
64
-
-
34248591731
-
Bioprocess membrane technology
-
Van Reis R, Zydney AL. 2007. Bioprocess membrane technology. J Membrane Sci 297:16-50.
-
(2007)
J Membrane Sci
, vol.297
, pp. 16-50
-
-
Van Reis, R.1
Zydney, A.L.2
-
65
-
-
0031576728
-
Simulated moving bed in the production of lysine
-
Van Walsem HJ, Thompson MC. 1997. Simulated moving bed in the production of lysine. J Biotechnol 59:127-132.
-
(1997)
J Biotechnol
, vol.59
, pp. 127-132
-
-
Van Walsem, H.J.1
Thompson, M.C.2
-
66
-
-
46649090963
-
Design and economics of industrial production of fructooligosaccharides
-
Vankova K, Onderkova Z, Antosova M, Polakovic M. 2008. Design and economics of industrial production of fructooligosaccharides. Chemical Papers 62:375-381.
-
(2008)
Chemical Papers
, vol.62
, pp. 375-381
-
-
Vankova, K.1
Onderkova, Z.2
Antosova, M.3
Polakovic, M.4
-
67
-
-
0037027815
-
Continuous annular chromatography: General characterization and application for the isolation of recombinant protein drugs
-
Vogel JH, Nguyen H, Pritschet M, Van Wegen R, Konstantinov K. 2002. Continuous annular chromatography: General characterization and application for the isolation of recombinant protein drugs. Biotechnol Bioeng 80:559-568.
-
(2002)
Biotechnol Bioeng
, vol.80
, pp. 559-568
-
-
Vogel, J.H.1
Nguyen, H.2
Pritschet, M.3
Van Wegen, R.4
Konstantinov, K.5
-
68
-
-
84868120447
-
Large-scale manufacturing platform for complex biopharmaceuticals
-
Vogel JH, Nguyen H, Giovanni R, Ignowski J, Garger S, Saigotra A, Tom J. 2012. Large-scale manufacturing platform for complex biopharmaceuticals. Biotechnol Bioeng 109:3049-3058.
-
(2012)
Biotechnol Bioeng
, vol.109
, pp. 3049-3058
-
-
Vogel, J.H.1
Nguyen, H.2
Giovanni, R.3
Ignowski, J.4
Garger, S.5
Saigotra, A.6
Tom, J.7
-
69
-
-
0037572331
-
Potential of cell retention techniques for large-scale high-density perfusion culture of suspended mammalian cells
-
Voisard D, Meuwly F, Ruffieux P-A., Baer G, Kadouri A. 2003. Potential of cell retention techniques for large-scale high-density perfusion culture of suspended mammalian cells. Biotechnol Bioeng 82:751-765.
-
(2003)
Biotechnol Bioeng
, vol.82
, pp. 751-765
-
-
Voisard, D.1
Meuwly, F.2
Ruffieux, P.-A.3
Baer, G.4
Kadouri, A.5
-
70
-
-
84868158860
-
Integrated continuous production of recombinant therapeutic proteins
-
Warikoo V, Godawat R. Brower K, Jain S, Cummings D, Simons S, Johnson T, Walther J, Yu M, Wright B, McLarty J, Karey K, Hwang C, Zhou W, Riske F, Konstantinov K. 2012. Integrated continuous production of recombinant therapeutic proteins. Biotechnol Bioeng 109:3018-3029.
-
(2012)
Biotechnol Bioeng
, vol.109
, pp. 3018-3029
-
-
Warikoo, V.1
Godawat, R.2
Brower, K.3
Jain, S.4
Cummings, D.5
Simons, S.6
Johnson, T.7
Walther, J.8
Yu, M.9
Wright, B.10
McLarty, J.11
Karey, K.12
Hwang, C.13
Zhou, W.14
Riske, F.15
Konstantinov, K.16
-
71
-
-
33745807268
-
Bioreactor systems for the production of biopharmaceuticals from animal cells
-
Warnock JN, Al-Rubeai M. 2006. Bioreactor systems for the production of biopharmaceuticals from animal cells. Biotechnol Appl Biochem 45:1-12.
-
(2006)
Biotechnol Appl Biochem
, vol.45
, pp. 1-12
-
-
Warnock, J.N.1
Al-Rubeai, M.2
-
72
-
-
84871722586
-
Anion exchange membrane adsorbers for flow-through polishing steps: Part II. Virus, host cell protein, DNA clearance, and antibody recovery
-
Weaver J, Husson SM, Murphy L, Wickramasinghe SR. 2013. Anion exchange membrane adsorbers for flow-through polishing steps: Part II. Virus, host cell protein, DNA clearance, and antibody recovery. Biotechnol Bioeng 110:500-510.
-
(2013)
Biotechnol Bioeng
, vol.110
, pp. 500-510
-
-
Weaver, J.1
Husson, S.M.2
Murphy, L.3
Wickramasinghe, S.R.4
-
73
-
-
84955658511
-
-
Apparatus and Method for Continuous Lyophilization. 2013
-
Weisselberg, E. 2013 Apparatus and Method for Continuous Lyophilization. 2013. U.S. Patent 8, 528, 225.
-
(2013)
-
-
Weisselberg, E.1
-
74
-
-
0034647042
-
A novel perfusion system for animal cell cultures by two step sequential sedimentation
-
Wen Z-H, Teng X-W, Chen F. 2000. A novel perfusion system for animal cell cultures by two step sequential sedimentation. J Biotechnol 79:1-11.
-
(2000)
J Biotechnol
, vol.79
, pp. 1-11
-
-
Wen, Z.-H.1
Teng, X.-W.2
Chen, F.3
-
76
-
-
80053090101
-
Towards protein crystallization as a process step in downstream processing of therapeutic antibodies: Screening and optimization at microbatch scale
-
Zang Y, Kammerer B, Eisenkolb M, Lohr K, Kiefer H. 2011. Towards protein crystallization as a process step in downstream processing of therapeutic antibodies: Screening and optimization at microbatch scale. PloS ONE 6:1-8.
-
(2011)
PloS ONE
, vol.6
, pp. 1-8
-
-
Zang, Y.1
Kammerer, B.2
Eisenkolb, M.3
Lohr, K.4
Kiefer, H.5
-
77
-
-
84901923819
-
Design and operation of continuous countercurrent chromatography in biotechnological production
-
Zobel S, Helling C, Ditz R, Strube J. 2014. Design and operation of continuous countercurrent chromatography in biotechnological production. Ind Eng Chem Res 53:9169-9185.
-
(2014)
Ind Eng Chem Res
, vol.53
, pp. 9169-9185
-
-
Zobel, S.1
Helling, C.2
Ditz, R.3
Strube, J.4
-
78
-
-
0000411067
-
High performance tangential flow filtration
-
In: Wang WK, editor. . New York: Marcel Dekker.
-
Zydney AL, van Reis R. 2001. High performance tangential flow filtration. In: Wang WK, editor. Membrane separations in biotechnology, 2nd ed. New York: Marcel Dekker. p 277-298.
-
(2001)
Membrane separations in biotechnology, 2nd ed
, pp. 277-298
-
-
Zydney, A.L.1
van Reis, R.2
|