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Volumn 12, Issue 1, 1996, Pages 57-64

Practical considerations in operation and scale-up of spin-filter based bioreactors for monoclonal antibody production

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; FERMENTATION; FOULING; MATHEMATICAL MODELS; MONOCLONAL ANTIBODIES; SCANNING ELECTRON MICROSCOPY;

EID: 0030019157     PISSN: 87567938     EISSN: None     Source Type: Journal    
DOI: 10.1021/bp950079p     Document Type: Article
Times cited : (78)

References (11)
  • 1
    • 11944254486 scopus 로고
    • Spin-filter perfusion system for high density cell culture: Production of recombinant urinary type plasminogen activator in CHO cells
    • Avgerinos, G. C.; Drapeau, D.; Socolow, J. S.; Mao, J.; Hsiao, K.; Broeze, R. J. Spin-filter perfusion system for high density cell culture: Production of recombinant urinary type plasminogen activator in CHO cells. Bio / Technology 1990, 8, 54-58.
    • (1990) Bio / Technology , vol.8 , pp. 54-58
    • Avgerinos, G.C.1    Drapeau, D.2    Socolow, J.S.3    Mao, J.4    Hsiao, K.5    Broeze, R.J.6
  • 2
    • 0029104088 scopus 로고
    • In pursuit of the optimal fed-batch process for monoclonal antibody production
    • Bibila, T. A.; Robinson, D. K. In pursuit of the optimal fed-batch process for monoclonal antibody production. Biotechnol. Prog. 1995, 11, 1-13.
    • (1995) Biotechnol. Prog. , vol.11 , pp. 1-13
    • Bibila, T.A.1    Robinson, D.K.2
  • 4
    • 0026173338 scopus 로고
    • Influence of the screen material on the fouling of spin-filters
    • Esclade, L. R. J.; Carrel, S.; Peringer, P. Influence of the screen material on the fouling of spin-filters. Biotechnol. Bioeng. 1991, 38, 159-168.
    • (1991) Biotechnol. Bioeng. , vol.38 , pp. 159-168
    • Esclade, L.R.J.1    Carrel, S.2    Peringer, P.3
  • 5
    • 0014661176 scopus 로고
    • Spin-filter culture: The propagation of mammalian cells in suspension
    • Himmelfarb, P.; Thayer, P. S.; Martin, H. E. Spin-filter culture: The propagation of mammalian cells in suspension. Science 1969, 164, 555-557.
    • (1969) Science , vol.164 , pp. 555-557
    • Himmelfarb, P.1    Thayer, P.S.2    Martin, H.E.3
  • 8
    • 0019785505 scopus 로고
    • Large scale rotating filter perfusion system for high density growth of mammalian suspension cultures
    • Tolbert, W. R.; Feder, J.; Kimes, R. S. Large scale rotating filter perfusion system for high density growth of mammalian suspension cultures. In Vitro 1981, 17, 885-890.
    • (1981) In Vitro , vol.17 , pp. 885-890
    • Tolbert, W.R.1    Feder, J.2    Kimes, R.S.3
  • 9
    • 0023082297 scopus 로고
    • Use of a rotating wire cage for retention of animal cells in a perfusion fermenter
    • Varecka, R.; Scheirer, W. Use of a rotating wire cage for retention of animal cells in a perfusion fermenter. Dev. Biol. Stand. 1987, 66, 269-272.
    • (1987) Dev. Biol. Stand. , vol.66 , pp. 269-272
    • Varecka, R.1    Scheirer, W.2
  • 10
    • 0026737391 scopus 로고
    • Mammalian cell retention in a spin-filter perfusion bioreactor
    • Yabannavar, V. M.; Singh, V.; Connelly, N. V. Mammalian cell retention in a spin-filter perfusion bioreactor. Biotechnol. Bioeng. 1992, 40, 925-933.
    • (1992) Biotechnol. Bioeng. , vol.40 , pp. 925-933
    • Yabannavar, V.M.1    Singh, V.2    Connelly, N.V.3
  • 11
    • 0027976952 scopus 로고
    • Scale up of spin-filter perfusion bioreactor for mammalian cell retention
    • Yabannavar, V. M.; Singh, V.; Connelly, N. V. Scale up of spin-filter perfusion bioreactor for mammalian cell retention. Biotechnol. Bioeng. 1994, 43, 159-164.
    • (1994) Biotechnol. Bioeng. , vol.43 , pp. 159-164
    • Yabannavar, V.M.1    Singh, V.2    Connelly, N.V.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.