Countercurrent tangential chromatography for large-scale protein purification

Biotechnology and Bioengineering

Volumn 108, Issue 3, 2011, Pages 582-591

  Shinkazh, Oleg ^a   Kanani, Dharmesh ^b   Barth, Morgan ^b   Long, Matthew ^b   Hussain, Daniar ^c   Zydney, Andrew L ^b  

^a Chromatan Inc   (United States)

^b The Pennsylvania State University   (United States)

^c American Pioneer Ventures Ltd   (United States)

Author keywords

Chromatography; Disposable; Downstream processing; Hollow fiber membrane; Ion exchange; Microfiltration; Protein purification

Indexed keywords

ANION EXCHANGE RESINS; BOVINE SERUM ALBUMINS; CARDIO-VASCULAR DISEASE; COUNTER CURRENT; CRITICAL FLUX; DISPOSABLE; DOWNSTREAM-PROCESSING; FLOWTHROUGH; GENETIC DISORDERS; HIGH-RESOLUTION SEPARATIONS; HOLLOW FIBER; HOLLOW FIBER MEMBRANE MODULES; HOLLOW FIBER MEMBRANES; MODEL PROTEINS; PROTEIN PURIFICATION; PURIFICATION PROCESS; STATIC MIXERS; TARGET PROTEINS; THERAPEUTIC PROTEIN; TWO STAGE;

BODY FLUIDS; CELL CULTURE; DISEASES; FIBERS; ION EXCHANGE; IONS; MICROFILTRATION; PROTEINS; PURIFICATION; RESINS;

COLUMN CHROMATOGRAPHY;

RESIN;

ARTICLE; CELL CULTURE; CHROMATOGRAPHY; KINETICS; PROTEIN BINDING; PROTEIN PURIFICATION; SEPARATION TECHNIQUE;

ANIMALS; BIOTECHNOLOGY; CATTLE; CHROMATOGRAPHY, LIQUID; MYOGLOBIN; SERUM ALBUMIN, BOVINE;

BOVINAE;

EID: 78751525301     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.22960     Document Type: Article

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