Twin-column CaptureSMB: A novel cyclic process for protein A affinity chromatography

Journal of Chromatography A

Volumn 1389, Issue , 2015, Pages 85-95

  Angarita, Monica ^a   Müller Späth, Thomas ^a,b   Baur, Daniel ^a   Lievrouw, Roel ^c   Lissens, Geert ^c   Morbidelli, Massimo ^a  

^a ETH ZURICH   (Switzerland)

^b CHROMACON AG   (Switzerland)

^c JSR Micro NV Belgium   (Belgium)

Author keywords

Breakthrough curve; Monoclonal antibody; Periodic counter current chromatography; Protein A affinity chromatography; Sequential capture

Indexed keywords

AFFINITY CHROMATOGRAPHY; BATCH DATA PROCESSING; LIQUID CHROMATOGRAPHY; MONOCLONAL ANTIBODIES; QUALITY CONTROL; RESINS;

BREAK THROUGH CURVE; COUNTERCURRENT CHROMATOGRAPHY; ECONOMIC EVALUATIONS; MONOCLONAL ANTIBODIES (MAB); PERIODIC COUNTER-CURRENT CHROMATOGRAPHIES; PRODUCT CONCENTRATION; PROTEIN A; SEQUENTIAL CAPTURE;

COLUMN CHROMATOGRAPHY;

MONOCLONAL ANTIBODY; RESIN; BUFFER; STAPHYLOCOCCUS PROTEIN A;

AFFINITY CHROMATOGRAPHY; ANIMAL CELL; ANTIBODY TITER; ARTICLE; BATCH CHROMATOGRAPHY; BATCH PROCESS; BINDING AFFINITY; CHROMATOGRAPHY; CONTROLLED STUDY; COUNTER CURRENT CHROMATOGRAPHY; ECONOMIC EVALUATION; FLOW RATE; MANUFACTURING INDUSTRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN A AFFINITY CHROMATOGRAPHY; CHEMISTRY; DEVICES; ECONOMICS; PROCEDURES;

ANTIBODIES, MONOCLONAL; BUFFERS; CHROMATOGRAPHY, AFFINITY; STAPHYLOCOCCAL PROTEIN A;

EID: 84930377472     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2015.02.046     Document Type: Article

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