Early life exposure to fructose alters maternal, fetal and neonatal hepatic gene expression and leads to sex-dependent changes in lipid metabolism in rat offspring

PLoS ONE

Volumn 10, Issue 11, 2015, Pages

  Clayton, Zoe E ^a,c   Vickers, Mark H ^a   Bernal, Angelica ^a   Yap, Cassandra ^a,d   Sloboda, Deborah M ^b  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

^b MCMASTER UNIVERSITY   (Canada)

^c UNIVERSITY OF SYDNEY   (Australia)

^d UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CRYOPYRIN; FRUCTOKINASE; FRUCTOSE; INTERLEUKIN 1BETA; MESSENGER RNA; TRIACYLGLYCEROL; CIRCADIAN RHYTHM SIGNALING PROTEIN; FATTY ACID; GLYCOGEN;

ADULT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALORIC INTAKE; CONTROLLED STUDY; DIETARY INTAKE; ENDOPLASMIC RETICULUM STRESS; FATTY ACID METABOLISM; FEMALE; FETUS; GENE EXPRESSION PROFILING; GLYCOGEN ANALYSIS; GLYCOGEN LIVER LEVEL; HEXOSE TRANSPORT; LIPID METABOLISM; LIPOGENESIS; LIVER CELL DAMAGE; LIVER LEVEL; MALE; NEWBORN; NONHUMAN; PERINATAL PERIOD; PROGENY; RAT; REAL TIME POLYMERASE CHAIN REACTION; TRIACYLGLYCEROL LIVER LEVEL; ANIMAL; BLOOD; BODY WEIGHT; DRUG EFFECTS; EMBRYOLOGY; FOLLOW UP; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; LIVER; MATERNAL NUTRITION; METABOLISM; PREGNANCY; PRENATAL EXPOSURE; RANDOMIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEX DIFFERENCE; TIME FACTOR; WISTAR RAT;

ANIMALS; ANIMALS, NEWBORN; BODY WEIGHT; CIRCADIAN RHYTHM SIGNALING PEPTIDES AND PROTEINS; ENDOPLASMIC RETICULUM STRESS; FATTY ACIDS, NONESTERIFIED; FEMALE; FOLLOW-UP STUDIES; FRUCTOSE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GLYCOGEN; LIPID METABOLISM; LIVER; MALE; MATERNAL NUTRITIONAL PHYSIOLOGICAL PHENOMENA; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RANDOM ALLOCATION; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEX FACTORS; TIME FACTORS;

EID: 84955489537     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0141962     Document Type: Article

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